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Deep endometriosis

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https://www.readbyqxmd.com/read/29678755/colorectal-anastomotic-stenosis-lesson-learned-after-1643-colorectal-resections-for-deep-infiltrating-endometriosis
#1
Elisa Bertocchi, Giuliano Barugola, Marco Benini, Paolo Bocus, Roberto Rossini, Marcello Ceccaroni, Giacomo Ruffo
STUDY OBJECTIVE: To evaluate incidence, risk factors, and treatment of colorectal anastomotic stenosis in patients who underwent rectosigmoid resection for deep infiltrating endometriosis (DIE). DESIGN: A retrospective analysis of prospective database (Canadian Task Force classification III). SETTING: Public Medical Center PATIENTS: All women who underwent laparoscopic rectosigmoid resections for DIE between January 2002 and December 2016...
April 17, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29675360/deep-infiltrating-endometriosis-mr-imaging-with-surgical-correlation
#2
REVIEW
Xue Tang, Rennan Ling, Jingshan Gong, Dongdong Mei, Yan Luo, Minge Li, Jianmin Xu, Liguo Ma
In this pictorial review, MR imaging findings of deep infiltrating endometriosis (DIE) are illustrated together with surgical correlation. DIE can appear as irregular nodules or plaques with similar signal intensity to muscle on both T1-weighted and T2-weighted images. Hemorrhage foci and strands or stellate margins are also often noted. Restriction of diffusion can be seen on diffusion-weighted image. Fibrosis and adhesions often result in morphologic changes, such as alimentary tract tortuosity, irregular or nodular thickening of uterosacral ligaments, and partial or complete obliteration of the pouch of Douglas...
March 2018: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/29666722/postmenopausal-deep-infiltrating-endometriosis-of-the-colon-rare-location-and-novel-medical-therapy
#3
Benjamin M Snyder, Joseph W Beets, Bruce A Lessey, Samuel R W Horton, Gary A Abrams
We report an uncommon case of deep infiltrating endometriosis of the colon presenting as iron deficiency anemia nine years after hysterectomy with bilateral salpingo-oophorectomy. The endometrial implant was found at the hepatic flexure, an exceedingly rare location for endometriosis invasion with no cases distinctly reported in the literature. Additionally, the presentation of gastrointestinal endometriosis as iron deficiency anemia is not well documented in the literature. Instead of surgery, we prescribed a novel medical therapeutic approach using conjugated estrogen-bazedoxifene to antagonize the proliferative effects of estrogen on endometrial tissue...
2018: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/29664797/functional-outcomes-after-rectal-resection-for-deep-infiltrating-pelvic-endometriosis-long-term-results
#4
Suna Erdem, Sara Imboden, Andrea Papadia, Susanne Lanz, Michael D Mueller, Beat Gloor, Mathias Worni
BACKGROUND: Curative management of deep infiltrating endometriosis requires complete removal of all endometriotic implants. Surgical approach to rectal involvement has become a topic of debate given potential postoperative bowel dysfunction and complications. OBJECTIVE: This study aims to assess long-term postoperative evacuation and incontinence outcomes after laparoscopic segmental rectal resection for deep infiltrating endometriosis involving the rectal wall...
April 16, 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29656149/total-laparoscopic-ureteroneocystostomy-for-ureteral-endometriosis-a-single-center-experience-of-160-consecutive-patients
#5
Marcello Ceccaroni, Matteo Ceccarello, Giuseppe Caleffi, Roberto Clarizia, Stefano Scarperi, Mauro Pastorello, Alberto Molinari, Giacomo Ruffo, Stefano Cavalleri
STUDY OBJECTIVE: To investigate the efficacy of laparoscopic ureteroneocystostomy in patients with deep infiltrating endometriosis (DIE) with ureteral, parametrial, and bowel involvement. DESIGN: Prospective study (Canadian Task Force classification II-2). SETTING: Tertiary referral center for endometriosis care. PATIENTS: One hundred and sixty patients with DIE underwent laparoscopic radical eradication and ureteroneocystostomy between January 2009 and December 2016...
April 12, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29619523/-mushroom-cap-sign-in-deep-rectosigmoid-endometriosis
#6
REVIEW
Noelia Arévalo, Ramiro Méndez
No abstract text is available yet for this article.
April 4, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29609193/female-sexual-function-in-women-with-suspected-deep-infiltrating-endometriosis
#7
Ryane Vieira Lima, Ana Maria Gomes Pereira, Fernando Bray Beraldo, Cláudia Gazzo, João Alfredo Martins, Reginaldo Guedes Coelho Lopes
OBJECTIVE:  To evaluate the quality of the sexual function of women with suspected deep infiltrating endometriosis. METHODS:  A cross-sectional, observational and prospective study was conducted between May 2015 and August 2016, in which 67 patients with deep infiltrating endometriosis, suspected or diagnosed, were assessed for epidemiological and clinical characteristics, such as pain level through a visual analog scale (VAS), features of deep infiltrating endometriosis lesions and score on the Female Sexual Function Index (FSFI) before the onset of treatment...
March 2018: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/29587615/25-hydroxyvitamin-d-serum-levels-and-endometriosis-results-of-a-case-control-study
#8
Laura Buggio, Edgardo Somigliana, Mara Nicoletta Pizzi, Dhouha Dridi, Elena Roncella, Paolo Vercellini
The immunomodulatory, anti-inflammatory, and antiproliferative properties of vitamin D have laid the basis for a possible function of this prohormone in the pathogenesis of endometriosis. The aim of this case-control study was to investigate vitamin D status, by measuring 25-hydroxyvitamin D [25(OH)D] serum levels, in women with and without endometriosis. Only Italian women of Caucasian origin aged between 18 and 45 years were deemed eligible. Enrollment was limited to the period October to May. Cases and controls were matched for month of recruitment and secondarily for age and parity...
January 1, 2018: Reproductive Sciences
https://www.readbyqxmd.com/read/29551300/-first-line-management-without-ivf-of-infertility-related-to-endometriosis-result-of-medical-therapy-results-of-ovarian-superovulation-results-of-intrauterine-insemination-cngof-has-endometriosis-guidelines
#9
J Boujenah, P Santulli, E Mathieu-d'Argent, C Decanter, C Chauffour, P Poncelet
INTRODUCTION: Using the structured methodology of French guidelines (HAS-CNGOF), the aim of this chapter was to formulate good practice points (GPP), in relation to optimal non-ART management of endometriosis related to infertility, based on the best available evidence in the literature. MATERIALS AND METHODS: This guideline was produced by a group of experts in the field including a thorough systematic search of the literature (from January 1980 to March 2017)...
March 15, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29551299/-nerve-sparing-techniques-in-deep-endometriosis-surgery-to-prevent-urinary-or-digestive-functional-disorders-techniques-and-results-cngof-has-endometriosis-guidelines
#10
B Rabischong, R Botchorishvili, N Bourdel, S Curinier, S Campagne-Loiseau, J L Pouly, M Canis
OBJECTIVES: To evaluate the feasibility and functional urinary and digestive results of nerve sparing techniques in endometriosis surgery. METHODS: A research on the medline/pubmed database using specific keywords (nerve sparing, endometriosis, pelvic nerves) identified 7 publications among about 50 whose purpose was to describe the feasibility, the techniques and the functional results of nerve preservation in this indication. Among them there are: 2 uncontrolled retrospective studies, 3 prospective non-randomized studies, a meta-analysis and a review of the literature...
March 15, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29548620/-epidemiology-and-diagnosis-strategy-cngof-has-endometriosis-guidelines
#11
A Fauconnier, B Borghese, C Huchon, I Thomassin-Naggara, C-A Philip, T Gauthier, N Bourdel, A Denouel, A Torre, P Collinet, M Canis, X Fritel
Based on the best evidence available, we have provided guidelines for clinical practice to target the nature of endometriosis as a disease, the consequences of its natural history on management, and the clinical and imaging evaluation of the disease according to the level of care (primary care, specialized or referral). The frequency of endometriosis is unknown in the general population; endometriosis requires management when it causes symptoms (pain, infertility) or when it affect the function of an organ...
March 13, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29547736/the-presence-of-kras-ppp2r1a-and-arid1a-mutations-in-101-chinese-samples-with-ovarian-endometriosis
#12
Yang Zou, Jiang-Yan Zhou, Jiu-Bai Guo, Li-Qun Wang, Yong Luo, Zi-Yu Zhang, Fa-Ying Liu, Jun Tan, Feng Wang, Ou-Ping Huang
Endometriosis is a potential premalignant disorder. The underlying molecular aberrations, however, are not fully understood. A recent exome sequencing study found that 25% (10/39) of deep infiltrating endometriosis harbored cancer driver gene mutations. However, it is unclear whether these mutations also exist in ovarian endometriosis. Here, a total of 101 ovarian endometriosis samples were analyzed for the presence of these gene mutations, including KRAS, PPP2R1A, PIK3CA and ARID1A. In addition, 6 other cancer-associated genes (BRAF, NRAS, HRAS, ERK1, ERK2 and PTEN) were also analyzed...
March 9, 2018: Mutation Research
https://www.readbyqxmd.com/read/29545217/combined-transvaginal-transabdominal-pelvic-ultrasonography-accurately-predicts-the-3-dimensions-of-deep-infiltrating-bowel-endometriosis-measured-after-surgery-a-prospective-study-in-a-specialized-center-diagnostic-value-of-tv-ta-us-for-bowel-die
#13
Alessandra Di Giovanni, Lucia Casarella, Marina Coppola, Domenico Iuzzolino, Marianna Rasile, Mario Malzoni
STUDY OBJECTIVE: To assess sensitivity and accuracy of combined transvaginal/transabdominal ultrasonography for evaluation of deep infiltrating bowel endometriosis nodules measured after surgery. DESIGN: A prospective study (Canadian Task Force classification II.1). SETTING: A Center for Advanced Endoscopic Gynecologic Surgery from January 2014 to December 2016. PATIENTS: All women undergoing laparoscopic surgery and scheduled for segmental resection for clinically suspected bowel endometriosis...
March 12, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29545114/surgical-treatment-of-different-types-of-endometriosis-comparison-of-major-society-guidelines-and-preferred-clinical-algorithms
#14
REVIEW
Rosanne M Kho, Marina Paula Andres, Giuliano Moysés Borrelli, Joao Siufi Neto, Alan Zanluchi, Mauricio Simões Abrão
Treatment options for patients with different types of endometriosis - superficial, ovarian, or deep - vary depending on the clinical presentation. New findings in the recent years regarding the role of preoperative imaging, efficacy of medical therapy, and effect of surgery on ovarian reserve have changed the way we understand the disease and subsequently the way we treat our patients. Practicing clinicians frequently refer to published recommendations from major societies for treatment guidelines. This paper aims to present and compare the varying major society guidelines on the indications and best surgical treatment approach for the management of the different types of endometriosis...
February 16, 2018: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29544710/-deeply-infiltrating-endometriosis-and-infertility-cngof-has-endometriosis-guidelines
#15
E Mathieu d'Argent, J Cohen, C Chauffour, J L Pouly, J Boujenah, C Poncelet, C Decanter, P Santulli
Deeply infiltrating endometriosis is a severe form of the disease, defined by endometriotic tissue peritoneal infiltration. The disease may involve the rectovaginal septum, uterosacral ligaments, digestive tract or bladder. Deeply infiltrating endometriosis is responsible for disabling pain and infertility. The purpose of these recommendations is to answer the following question: in case of deeply infiltrating endometriosis associated infertility, what is the best therapeutic strategy? First-line surgery and then in vitro fertilization (IVF) in case of persistent infertility or first-line IVF, without surgery? After exhaustive literature analysis, we suggest the following recommendations: studies focusing on spontaneous fertility of infertile patients with deeply infiltrating endometriosis found spontaneous pregnancy rates about 10%...
March 12, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29544709/-performances-and-place-of-sonography-in-the-diagnostic-of-endometriosis-cngof-has-endometriosis-guidelines
#16
C-A Philip, G Dubernard
Endometriosis is difficult to diagnose clinically. Transvaginal sonography (TVS) is a procedure that is known to be operator-dependent, which mean that published evidences has to be balanced with the level of the sonographer that produced the data. The objective of this publication was to assess the performances of the sonography in the diagnosis of endometriosis in order to establish the French national recommendations. We searched the MEDLINE database for publication from January 2000 to September 2017 using keywords associated with endometriosis and sonography...
March 12, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29540335/-definition-description-clinicopathological-features-pathogenesis-and-natural-history-of-endometriosis-cngof-has-endometriosis-guidelines
#17
B Borghese, P Santulli, L Marcellin, C Chapron
Endometriosis and adenomyosis are histologically defined. The frequency of endometriosis cannot be precisely estimated in the general population. Endometriosis is considered a disease when it causes pain and/or infertility. Endometriosis is a heterogeneous disease with three well-recognized subtypes that are often associated with each other: superficial endometriosis (SUP), ovarian endometrioma (OMA), and deep infiltrating endometriosis (DIE). DIE is frequently multifocal and mainly affects the following structures: the uterosacral ligaments, the posterior vaginal cul-de-sac, the bladder, the ureters, and the digestive tract (rectum, recto-sigmoid junction, appendix)...
March 11, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29540333/-diagnostic-performance-of-mr-imaging-coloscan-and-mri-ct-enterography-for-the-diagnosis-of-pelvic-endometriosis-cngof-has-endometriosis-guidelines
#18
I Thomassin-Naggara, S Bendifallah, P Rousset, M Bazot, M Ballester, E Darai
Diagnostic performance of MR imaging for the diagnosis of pelvic endometriosis are good. Even if some differences of performances exists according the location considered, the risk of misdiagnosis is lower than 10% for trained teams (NP2). The performance of pelvic MR imaging and surgery are quite similar to diagnose endometrioma (sensitivity and specificity>90%). A negative pelvic MR imaging allows to exclude deep pelvic endometriosis with a performance similar to surgery but a positive MR imaging is less accurate than surgery because of a high number of false positives (23%)...
March 11, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29540112/enhanced-ugt1a1-gene-and-protein-expression-in-endometriotic-lesions
#19
Carla A Piccinato, Rosa M Neme, Natália Torres, Elivane da Silva Victor, Heloísa F Brudniewski, Júlio C Rosa E Silva, Rui A Ferriani
The cellular function in endometriosis lesions depends on a highly estrogenic milieu. Lately, it is becoming evident that, besides the circulating levels of estrogens, the balance of synthesis versus inactivation (metabolism) of estrogens by intralesion steroid-metabolizing enzymes also determines the local net estrogen availability. In order to extend the knowledge of the role of estrogen-metabolizing enzymes in endometriosis, we investigated the gene and protein expression of a key uridine diphospho-glucuronosyltransferase (UGT) for estrogen glucuronidation, UGT1A1, in eutopic endometrial samples obtained from nonaffected and endometriosis-affected women and also from endometriotic lesions...
January 1, 2018: Reproductive Sciences
https://www.readbyqxmd.com/read/29534879/-surgical-management-of-deep-endometriosis-with-colorectal-involvement-cngof-has-endometriosis-guidelines
#20
M Ballester, H Roman
Deep endometriosis with colorectal involvement is considered one of the most severe forms of the disease due to its impact on patients' quality of life and fertility but also by the difficulties encountered by the clinicians when proposing a therapeutic strategy. Although the literature is very rich, evidence based medicine remains poor explaining the great heterogeneity concerning the management of such patients. Surgery therefore remains a therapeutic option. It improves the intensity of gynecological, digestive and general symptoms and the quality of life...
March 2018: Gynecologie, Obstetrique, Fertilite & Senologie
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