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Deep endometriosis

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https://www.readbyqxmd.com/read/27905697/management-of-infertile-women-with-pelvic-endometriosis-a-literature-review
#1
Elisabeth Guinard, Pierre Collinet, Catherine Lefebvre, Geoffroy Robin, Chrystele Rubod
INTRODUCTION: Endometriosis is a condition that affects women's fertility. Several mechanisms are involved in this process: anatomical changes, mechanical, immune or inflammatory factors, ovarian reserve alterations. There are different types of strategies to treat endometriosis-related infertility: medical treatment, surgical treatment and / or techniques of medically assisted procreation. EVIDENCE ACQUISITION: We tried to consider various therapeutic strategies depending on the stage of the disease in order to offer appropriate management to patients with endometriosis who wish to become pregnant: we reviewed 58 articles between 1985 to 2016 searching in medline using the key words "endometriosis and infertility" and "infertility and endometriosis treatment"...
December 1, 2016: Minerva Ginecologica
https://www.readbyqxmd.com/read/27899313/prognostic-factors-for-assisted-reproductive-technology-in-women-with-endometriosis-related-infertility
#2
Chloé Maignien, Pietro Santulli, Vanessa Gayet, Marie-Christine Lafay-Pillet, Diane Korb, Mathilde Bourdon, Louis Marcellin, Dominique de Ziegler, Charles Chapron
BACKGROUND: Assisted reproductive technology is one of the therapeutic options offered for managing endometriosis-associated infertility. Yet, published data on assisted reproductive technology outcome in women affected by endometriosis are conflicting and the determinant factors for pregnancy chances unclear. OBJECTIVE: To evaluate assisted reproductive technology outcomes in a series of 359 endometriosis patients, to identify prognostic factors and determine if there is an impact of the endometriosis phenotype...
November 26, 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27897974/delayed-coloanal-anastomosis-for-rectovaginal-fistula-after-colorectal-resection-for-deep-endometriosis
#3
Gaetano Gallo, Alberto Realis Luc, Roberta Tutino, Giuseppe Clerico, Mario Trompetto
AIM: The deep infiltrating endometriosis, defined as a subperitoneal infiltration of endometrial implants of ≥ 5 mm involving not only the colorectal tract but also rectovaginal septum, vagina and bladder often requires a challenging surgery. Endometriosis nodes of the rectovaginal septum, if symptomatic, need a resection of the involved colorectal tract with colorectal or coloanal anastomosis. Unfortunately in these cases is not uncommon the possibility of a postoperative rectovaginal fistula (RVF), caused by the weakness of the septum that must be skeletonized to completely remove the endometriosis nodes...
November 28, 2016: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/27887713/magnetic-resonance-imaging-correlation-to-intraoperative-findings%C3%A2-of-deeply-infiltrative-endometriosis
#4
Traci E Ito, Elias D Abi Khalil, Myles Taffel, Gaby N Moawad
OBJECTIVE: To show characteristics of deeply infiltrative endometriosis (DIE) on magnetic resonance imaging (MRI) and how they correlate with intraoperative findings. DESIGN: Overview of still and dynamic MRI images of four different patients with DIE. We then used videos from their surgeries to highlight the appearance of endometriosis corresponding to these images (educational video). SETTING: University hospital. PATIENT(S): Four different patients with DIE were included in this video...
November 22, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27885759/transanal-minimally-invasive-rectal-resection-for-deep-endometriosis-a-promising-technique
#5
Stijn L Vlek, Marit C I Lier, Thomas W A Koedam, Ingeborg Melgers, Judith J M L Dekker, Jaap H Bonjer, Velja Mijatovic, Jurriaan B Tuynman
AIM: Surgical management of patients with deep endometriosis (DE) of the rectum is difficult. Inflammation and subsequent adhesions due to DE impede access to the lower pelvis and may lead to complications during laparoscopic low anterior resection (LAR). Transanal minimally invasive surgery (TAMIS) is an alternative to an abdominal approach with potential advantages. The aim of this study was to provide a description of the TAMIS technique and to present the perioperative results of TAMIS and of conventional LAR in patients with DE...
November 25, 2016: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/27872758/thrombosis-of-iliac-vessels-a-rare-complication-of-endometriosis-case-report-and-review-of-literature
#6
Rita Chiaramonte, Salvatore Castorina, Emilio Giovanni Castorina, Alessandra Panarello, Salvatore Alessandro Maria Antoci
A young women presented with iliac vein thrombosis, as extrapelvic endometriosis complication. Endometriosis mass had a subfascial position at the level of external oblique muscle and extended to the iliac vein. This paper reviewed the literature on endometriosis cases localized into striated muscles and cases of deep vein thrombosis due to this disease. There are not similar cases in the literature. The diagnostic role of ultrasound, in obtaining the definitive histological diagnosis, may be further enhanced through Elasticity Imaging Techniques and ultrasound-guided biopsy...
January 2017: Journal of Advanced Research
https://www.readbyqxmd.com/read/27861710/endometriosis-and-uterine-malformations-infertility-may-increase-severity-of-endometriosis
#7
Jeremy Boujenah, Eleonora Salakos, Mélodie Pinto, Joanna Shore, Christophe Sifer, Christophe Poncelet, Alexandre Bricou
INTRODUCTION: The aim of our study was to compare the stage and severity of endometriosis in fertile and infertile women with congenital uterine malformations. MATERIAL AND METHODS: We performed an observational study from September 2007 to December 2015 in a tertiary care university hospital and assisted reproductive technology center. A total of 52 patients with surgically proven uterine malformations were included. We compared 41 infertile patients with uterine malformations with 11 fertile patients with uterine malformation...
October 13, 2016: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/27836223/combined-effect-of-vascular-endothelial-growth-factor-and-its-receptor-polymorphisms-in-endometriosis-a-case-control-study
#8
Jéssica Vilarinho Cardoso, Maurício Simões Abrão, Rosane Vianna-Jorge, Renato Ferrari, Plínio Tostes Berardo, Daniel Escorsim Machado, Jamila Alessandra Perini
OBJECTIVE: Endometriosis is a multifactorial gynecological disease, whose pathogenesis is crucially dependent on angiogenesis, which is signaled via vascular endothelial growth factor (VEGF) and its receptor (VEGFR2). We hypothesize that single nucleotide polymorphisms (SNPs) in VEGF and VEGFR2 genes may influence the onset and/or the progression of endometriosis. The main aim of this study was to investigate the contribution of VEGF and VEGFR2 SNPs as risk factors for endometriosis, as well as their association with endometriosis symptoms...
October 29, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27832323/deep-pelvic-endometriosis-a-radiologist-s-guide-to-key-imaging-features-with-clinical-and-histopathologic-review
#9
REVIEW
Ayeh Darvishzadeh, Wendaline McEachern, Thomas K Lee, Priya Bhosale, Ali Shirkhoda, Christine Menias, Chandana Lall
While endometriosis typically affects the ovaries, deep infiltrating endometriosis can affect the gastrointestinal tract, urinary tract, and deep pelvis, awareness of which is important for radiologists. Symptoms are nonspecific and can range from chronic abdominal and deep pelvic pain to nausea, vomiting, diarrhea, constipation, hematuria, and rectal bleeding. Ultrasound and computed tomography may show nonspecific soft-tissue density masses causing bowel obstruction and hydronephrosis. This constellation of presenting symptoms and imaging evidence is easily mistaken for other pathologies including infectious gastroenteritis, diverticulitis, appendicitis, and malignancy, which may lead to unnecessary surgery or mismanagement...
November 10, 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27821707/the-cannabinoid-receptor-cb1-contributes-to-the-development-of-ectopic-lesions-in-a-mouse-model-of-endometriosis
#10
Ana-Maria Sanchez, Federica Quattrone, Maria Pannese, Adele Ulisse, Massimo Candiani, Javier Diaz-Alonso, Guillermo Velasco, Paola Panina-Bordignon
STUDY QUESTION: Does signaling via the cannabinoid (CB1) receptor play a role in the pathogenesis of endometriosis in a mouse model? SUMMARY ANSWER: Mice treated with a CB1 agonist developed larger ectopic lesions, while less severe lesions developed in the absence of functional CB1 expression. WHAT IS KNOWN ALREADY: The expression of components of the endocannabinoid system has been demonstrated in both mouse and human uteri. CB1 receptors are expressed in human epithelial and stromal cell lines derived from eutopic endometrium and deep infiltrating endometriosis nodules...
November 7, 2016: Human Reproduction
https://www.readbyqxmd.com/read/27821656/gel-sonovaginography-a-new-way-of-evaluating-a-variety-of-local-vaginal-and-cervical-disorders
#11
Mala Sibal
Gel sonovaginography is a new way of assessing local cervical and vaginal disorders, in which regular transvaginal sonography is known to have limitations. In gel sonovaginography, 20 mL of ultrasound gel is instilled into the vagina, followed by examination with a transvaginal transducer. In a study involving 28 women with known or suspected disorders such as cervical and vaginal cancer, cervical polyps, vaginal septa, and deep infiltrating endometriosis, a substantial improvement in visualization and assessment of local lesions and structures was noted with gel sonovaginography...
December 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/27817837/estrogen-progestins-and-progestins-for-the-management-of-endometriosis
#12
REVIEW
Paolo Vercellini, Laura Buggio, Nicola Berlanda, Giussy Barbara, Edgardo Somigliana, Silvano Bosari
Endometriosis is characterized by frequent recurrences of symptoms and lesions even after extirpative surgery. Because medical therapies control but do not cure the disease, long periods of pharmacologic management may be needed until pregnancy desire or, sometimes, physiologic menopause. Hormonal drugs suppress ovulation and menstruation and have similar beneficial effects against pain. However, only estrogen-progestins and progestins have safety/tolerability/cost profiles that allow long-term use. These compounds induce atrophy of eutopic and ectopic endometrium, have antiinflammatory and proapoptotic properties, and can be delivered via different modalities, including oral, transdermal, subcutaneous, intramuscular, vaginal, and intrauterine routes...
December 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27778641/progesterone-resistance-in-endometriosis-is-modulated-by-the-altered-expression-of-microrna-29c-and-fkbp4
#13
Niraj R Joshi, Eduardo H Miyadahira, Yalda Afshar, Jae-Wook Jeong, Steven L Young, Bruce A Lessey, Paulo C Serafini, Asgerally T Fazleabas
CONTEXT: Endometriosis results in aberrant gene expression in the eutopic endometrium(EuE) and subsequent progesterone(P) resistance. MicroRNA(miR) microarray data in a baboon model of endometriosis showed an increased expression of miR-29c. OBJECTIVES: To explore the role of miR-29c in P resistance in a subset of women with endometriosis. DESIGN: MiR-29c expression was analyzed in the endometrium of baboons and women with or without endometriosis...
October 25, 2016: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27770245/new-adverse-obstetrics-outcomes-associated-with-endometriosis-a-retrospective-cohort-study
#14
Luca Mannini, Flavia Sorbi, Ivo Noci, Viola Ghizzoni, Federica Perelli, Mariarosaria Di Tommaso, Alberto Mattei, Massimiliano Fambrini
PURPOSE: The main aim of this study was to evaluate the incidence of endometriosis and intrahepatic cholestasis (ICP) and induction of labor in pregnant women with endometriosis compared with women without endometriosis. The secondary aim was to confirm increased incidence of already known endometriosis-related pregnancy complications in these patients. METHODS: This is a retrospective cohort study performed at a tertiary hospital between January 2009 and December 2014 to compare obstetrics outcome between women with endometriosis and women without endometriosis...
October 21, 2016: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/27770131/incarceration-of-the-gravid-uterus
#15
Kelsey L Shnaekel, Michael P Wendel, Nader Z Rabie, Everett F Magann
Objective: The aim of this review was to describe the risk factors, clinical and radiographic criteria, and management of this rare complication of pregnancy. Methods: A PubMed, Web of Science, and CINAHL search was undertaken with no limitations on the number of years searched. Results: There were 60 articles identified, with 53 articles being the basis of this review. Multiple risk factors have been suggested in the literature including retroverted uterus in the first trimester, deep sacral concavity with an overlying sacral promontory, endometriosis, previous abdominal or pelvic surgery, pelvic or uterine adhesions, ovarian cysts, leiomyomas, multifetal gestation, uterine anomalies, uterine prolapse, and uterine incarceration in a prior pregnancy...
October 2016: Obstetrical & Gynecological Survey
https://www.readbyqxmd.com/read/27718502/pelvic-floor-muscle-dysfunction-at-3d-4d-transperineal-ultrasound-in-patients-with-deep-infiltrating-endometriosis-a-pilot-study
#16
Diego Raimondo, Aly Youssef, Mohamed Mabrouk, Simona Del Forno, Valentina Martelli, Gianluigi Pilu, Nicola Rizzo, Letizia Zannoni, Roberto Paradisi, Renato Seracchioli
OBJECTIVE: Pelvic floor muscle (PFM) dysfunction seems to play an important role in the pathophysiology of pain in women with with pelvic pain syndromes, including deep infiltrating endometriosis (DIE). The aim of the study was to evaluate static and dynamic morphometry of PFM in women affected by DIE, in comparison to asymptomatic control women, using three-dimensional (3D) and four-dimensional (4D) transperineal ultrasound. METHODS: A pilot, prospective study was conducted between March 2015 and November 2015, at our tertiary center...
October 8, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27710968/endometriotic-pain-is-associated-with-adenomyosis-but-not-with-the-compartments-affected-by-deep-infiltrating-endometriosis
#17
Maria Francesca Perelló, Maria Ángeles Martínez-Zamora, Ximena Torres, Jordina Munrós, Juan Balasch Cortina, Francisco Carmona
BACKGROUND: The identification of presurgical clinical markers may be helpful to allow the staging of endometriosis severity. It has been suggested that pain characteristics orientate the gynecologist about the anatomical involvement of endometriosis. The study was performed to analyze the correlation between pain symptoms and the anatomical location of endometriosis. METHODS: One hundred fifty-five consecutive patients with a complete removal of deep infiltrating endometriosis (DIE) were included...
October 7, 2016: Gynecologic and Obstetric Investigation
https://www.readbyqxmd.com/read/27693682/moose-antler-sign-a-sign-of-deep-endometriosis-infiltrating-bowel
#18
Vincent Della Zazzera, Harbinder Benning, Karine Lortie, Sukhbir Singh
No abstract text is available yet for this article.
September 28, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27679347/laparoscopic-bowel-resection-for-deep-infiltrating-endometriosis-the-care-experience
#19
P Hengrasmee, A Lam
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27679279/comparison-of-complete-and-incomplete-excision-of-deep-infiltrating-endometriosis
#20
J Ding, K Hua, Q Cao, F Lu
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
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