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https://www.readbyqxmd.com/read/27911432/-eye-lid-hygiene-in-chronic-allergic-blepharoconjunctivitis-patients-before-laser-refractive-surgery
#1
S V Yanchenko, A V Malyshev, S N Sakhnov, N V Fedotova, O Yu Orekhova
AIM: To evaluate the effectiveness of eyelid hygiene in patients with chronic allergic blepharoconjunctivitis (ABC) as a part of their preparation for laser refractive surgery. MATERIAL AND METHODS: The study involved 32 patients (12 males and 20 females aged 25-42 years) with refractive errors, namely, compound myopic astigmatism (23 patients) and hyperopic astigmatism (9 patients) suffering from chronic ABC and secondary dry eye syndrome (DES). All the patients initially received a standard treatment for ABC and DES, that is olopatodin hydrochloride instillations - 1 mg/ml 2 times daily, preservative-free hyaluronic acid preparation - 1 mg/ml 3 times daily, and polyacrylic acid and dexpanthenol gel at night for one month...
2016: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/27911425/-biometric-parameters-of-vitrectomized-eyes
#2
S V Asatryan, V K Surguch, S I Kharlap, T A Shchegoleva
AIM: To analyze changes in various biometric parameters after vitrectomy. MATERIAL AND METHODS: A total of 50 patients (50 eyes) were followed up. All of them underwent vitrectomy for idiopathic epiretinal fibrosis and macular hole. In addition to the standard ophthalmic examination, we performed a combined ultrasound study and ultrasound biomicroscopy before and after the surgery (at 2-3 weeks and 6 months). Variation statistics was applied to assess the results using the SPSS Statistica 20 software...
2016: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/27911420/-role-of-immunological-factors-in-the-development-of-myopic-choroidal-neovascularization
#3
A G Shchuko, N V Zaitseva, T N Yur'eva, E R Chernykh, I M Mikhalevich, A V Grigor'eva
AIM: To study the concentration of cytokines in the aqueous humor of the anterior chamber in patients with myopic choroidal neovascularization (mCNV) and to compare the results to their ophthalmic status. MATERIAL AND METHODS: A total of 19 patients (19 eyes) with mCNV treated with intravitreal ranibizumab were included in the study. The control group consisted of 15 patients (15 eyes) with myopia who had cataract surgery. Age, sex, and refractive error distribution were similar to that in the study group...
2016: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/27905334/the-opportunistic-screening-of-refractive-errors-in-school-going-children-by-pediatrician-using-enhanced-br%C3%A3-ckner-test
#4
Piyush Jain, Mihir T Kothari, Vaibhav Gode
AIM: The aim of this study was to compare the results of enhanced Brückner test (EBT) performed by a pediatrician and an experienced pediatric ophthalmologist. SUBJECTS AND METHODS: In this prospective double-masked cohort study, a pediatrician and a pediatric ophthalmologist performed the EBT in a classroom of a school in semi-dark lighting condition using a direct ophthalmoscope. The results of the test were compared using 2 × 2 Bayesian table and kappa statistics...
October 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27898445/pathologic-myopia
#5
Kyoko Ohno-Matsui
Pathologic myopia (PM) is the only myopia that causes the loss of best-corrected visual acuity. The main reason for best-corrected visual acuity loss is complications specific to PM, such as myopic maculopathy, myopic traction maculopathy, and myopic optic neuropathy (or glaucoma). The meta-analyses of the PM study group (META-PM study) made a classification system for myopic maculopathy. On the basis of this study, PM has been defined as eyes having atrophic changes equal to or more severe than diffuse atrophy...
November 2016: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/27896533/characteristics-of-higher-order-aberrations-and-anterior-segment-tomography-in-patients-with-pathologic-myopia
#6
Kaori Kasahara, Naoyuki Maeda, Takashi Fujikado, Makoto Tomita, Muka Moriyama, Mutsumi Fuchihata, Kyoko Ohno-Matsui
PURPOSE: To investigate prospectively the characteristics in the higher-order aberrations and anterior segment tomography in patients with pathologic myopia. METHODS: One hundred and twelve consecutive highly myopic patients (mean age 43.4 ± 9.3 years, spherical equivalent of refractive error ≥8 D and an axial length ≥26.5 mm) were studied. Thirty-seven emmetropic individuals (mean age 37.0 ± 14.5 years, spherical equivalent of refractive error ≤ ±1 D) were analyzed as controls...
November 28, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/27874105/patterns-in-longitudinal-growth-of-refraction-in-southern-chinese-children-cluster-and-principal-component-analysis
#7
Yanxian Chen, Billy Heung Wing Chang, Xiaohu Ding, Mingguang He
In the present study we attempt to use hypothesis-independent analysis in investigating the patterns in refraction growth in Chinese children, and to explore the possible risk factors affecting the different components of progression, as defined by Principal Component Analysis (PCA). A total of 637 first-born twins in Guangzhou Twin Eye Study with 6-year annual visits (baseline age 7-15 years) were available in the analysis. Cluster 1 to 3 were classified after a partitioning clustering, representing stable, slow and fast progressing groups of refraction respectively...
November 22, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27867659/ganglion-cell-inner-plexiform-layer-peripapillary-retinal-nerve-fiber-layer-and-macular-thickness-in-eyes-with-myopic-%C3%AE-zone-parapapillary-atrophy
#8
Jin-Woo Kwon, Jin A Choi, Jung-Sub Kim, Tae Yoon La
Purpose. To assess the correlations of myopic β-zone parapapillary atrophy (β-PPA) with the optic nerve head (ONH) and retina. Methods. We selected 27 myopic patients who showed prominent β-PPA in one eye and no β-PPA in the other eye. We studied their macula, macular ganglion cell-inner plexiform layer (mGCIPL), peripapillary retinal nerve fiber layer (pRNFL) thickness, and ONH parameters using optical coherence tomography. Results. The average of five out of six sectors and minimum values of mGCIPL thicknesses in eyes with prominent β-PPA discs were significantly less than those of the control eyes...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27860316/prevalence-of-myopic-retinopathy-in-rural-central-india
#9
Jost B Jonas, Vinay Nangia, Rajesh Gupta, Krishna Bhojwani, Prabhat Nangia, Songhomitra Panda-Jonas
PURPOSE: The aim of this study was to determine the prevalence of myopic retinopathy (MR) in rural Central India. METHODS: The population-based Central India Eye and Medical Study included 4711 subjects (aged 30+ years). The participants underwent a detailed eye examination, including fundus photography. Myopic retinopathy was defined according to the Pathologic Myopia Study Group. RESULTS: Readable fundus photographs were available on 4561 (96...
November 17, 2016: Acta Ophthalmologica
https://www.readbyqxmd.com/read/27853350/intravitreal-aflibercept-for-the-treatment-of-choroidal-neovascularization-associated-with-pathologic-myopia-a-pilot-study
#10
Andrii R Korol, Oleg S Zadorozhnyy, Volodymyr O Naumenko, Taras B Kustryn, Nataliya V Pasyechnikova
PURPOSE: To determine the efficacy of intravitreal aflibercept injections for the treatment of patients with choroidal neovascularization (CNV) associated with pathologic myopia. METHODS: In this uncontrolled, prospective cohort study, 31 eyes of 30 consecutive patients affected by CNV associated with pathologic myopia were treated with intravitreal aflibercept (2 mg) as needed following two initial monthly doses and observed over a 12-month follow-up period. The primary endpoint was change in best-corrected visual acuity (BCVA) at month 12, while central retinal thickness (CRT) on optical coherence tomography (OCT), neovascularization activity on fluorescein angiography, the number of aflibercept injections administered, and safety were examined as secondary endpoints...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27852402/-changes-of-ocular-biological-parameters-and-lumican-expression-in-the-monocularly-deprivation-myopic-model-of-mutant-lumican-transgenic-mice
#11
M S Sun, Y Z Song, F J Zhang, J Tao, Y B Liu
Objective: To investigate ocular changes in the monocularly deprivation myopic model of mutant Lumican transgenic mice. Comparing influences on biological parameters and sclera development between Lumican transgenic and form deprivation mice, and to prepare for further study of pathogenesis of pathological myopia (PM). Methods: Experimental research. Lumican transgenic mice and wild mice were monocularly lid-sutured at ten days after birth. All eyes were divided into 6 groups, group A(32 eyes): control eyes in transgenic mice; group B(34 eyes): sutured eyes in transgenic mice; group C(34 eyes): fellow eyes in transgenic mice; group D(28 eyes): control eyes in wild mice; group E(32 eyes): sutured eyes in wild mice; group F(32 eyes): fellow eyes in wild mice...
November 11, 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/27852401/-distribution-and-compensation-mechanism-of-aberrations-between-anterior-and-posterior-surface-of-the-cornea-in-myopia-and-myopic-astigmatism-eyes
#12
X J Li, Y Wang, Y N Wu, W J Wu, C J Yu, L L Xu
Objective: To study the compensation mechanism of aberrations between anterior and posterior corneal surface, and to investigate the correlations between corneal aberrations and K values, intraocular pressure and central corneal thickness. Methods: One hundred and sixty-one subjects (300 eyes) with myopia and myopic astigmatism were recruited randomly. Corneal aberrations (anterior, posterior and total) in three different optical zones (2 mm, 4 mm, and 6 mm) centered on the corneal vertex were assessed with a corneal topographer (Sirius)...
November 11, 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/27847624/prevalence-of-outer-retinal-tubulation-in-eyes-with-choroidal-neovascularization
#13
Richard Geraldo Giachetti Filho, Leandro Cabral Zacharias, Thaís Vera Monteiro, Rony Carlos Preti, Sérgio Gianoti Pimentel
BACKGROUND: Outer retinal tubulations (ORTs) are branching tubular structures located in the outer nuclear layer of the retina. The goal of this study is to determine the prevalence of ORTs observed in eyes with choroidal neovascularization (CNV) undergoing treatment with anti-angiogenic intravitreous injection (IVI) with anti-VEGF (vascular endothelial growth factor) at the Ophthalmology Department of a tertiary hospital in São Paulo, Brazil. METHODS: This is a descriptive study based on medical charts and Spectral-domain Optical Coherence Tomography (Sd-OCT) scans of 142 patients (158 eyes) treated between 2012 and 2014 with IVI of anti-VEGF for CNV...
2016: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/27846047/optic-nerve-head-histopathology-in-high-axial-myopia
#14
Jost B Jonas, Kyoko Ohno-Matsui, Songhomitra Panda-Jonas
PURPOSE: To describe particularities of the optic nerve head of axially highly myopic eyes. METHODS: Measurements were obtained from enucleated globes and from population-based studies. RESULTS: Morphologic optic disc particularities in high axial myopia included enlarged disc size (secondary macrodisc), widening and temporal translocation of the papillary Bruch's membrane (BM) opening, parapapillary gamma and delta zone, elongation and thinning of lamina cribrosa and peripapillary scleral flange, steeper translamina cribrosa pressure gradient, decreased peripapillary choroid thickness, longer distance between peripapillary arterial circle and optic disc, optic cup flattening, presumably a stretching of the lamina cribrosa pores, and peripapillary intrachoroidal cavitations...
November 11, 2016: Journal of Glaucoma
https://www.readbyqxmd.com/read/27832275/genome-wide-scleral-micro-and-messenger-rna-regulation-during-myopia-development-in-the-mouse
#15
Ravikanth Metlapally, Han Na Park, Ranjay Chakraborty, Kevin K Wang, Christopher C Tan, Jacob G Light, Machelle T Pardue, Christine F Wildsoet
Purpose: MicroRNA (miRNAs) have been previously implicated in scleral remodeling in normal eye growth. They have the potential to be therapeutic targets for prevention/retardation of exaggerated eye growth in myopia by modulating scleral matrix remodeling. To explore this potential, genome-wide miRNA and messenger RNA (mRNA) scleral profiles in myopic and control eyes from mice were studied. Methods: C57BL/6J mice (n = 7; P28) reared under a 12L:12D cycle were form-deprived (FD) unilaterally for 2 weeks...
November 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27830201/corneal-biomechanics-after-small-incision-lenticule-extraction-versus-q-value-guided-femtosecond-laser-assisted-in-situ-keratomileusis
#16
Jun Zhang, Li Zheng, Xia Zhao, Yang Xu, Shu Chen
PURPOSE: The aim of this study was to compare the changes in corneal biomechanical properties following small-incision lenticule extraction (SMILE) versus Q-value-guided femtosecond laser-assisted in situ keratomileusis (Q-FS-LASIK). METHODS: In this prospective comparative study, patients with a sphere plus cylinder measurement of less than -10.00 D and cylinder measurement of less than -5.00 D were included in the study. A total of 160 patients (160 eyes) with myopia and myopic astigmatism were divided into the two groups, with 80 patients (80 eyes) allocated to SMILE and 80 patients (80 eyes) allocated to Q-FS-LASIK...
December 2016: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/27824385/corneal-scheimpflug-densitometry-following-photorefractive-keratectomy-in-myopic-eyes
#17
Marie Boulze-Pankert, Romuald Dariel, Louis Hoffart
PURPOSE: To evaluate the modification of corneal optical densitometry following photorefractive keratectomy (PRK) using Scheimpflug topography. METHODS: Corneal densitometry (0 to 100 grayscale units [GSU]), pachymetry, and keratometry were evaluated using a rotating Scheimpflug camera (Pentacam HR; Oculus Optikgeräte, GmbH, Wetzlar, Germany) at baseline and 1 and 3 months following PRK in myopic patients. Subjective refraction, uncorrected distance visual acuity, corrected distance visual acuity, and corneal haze (0 to 4 on common subjective scale) were evaluated preoperatively at baseline, 1 month, and 3 months...
November 1, 2016: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/27820633/retinal-microvasculature-alteration-in-high-myopia
#18
Ye Yang, Jianhua Wang, Hong Jiang, Xiaoling Yang, Limiao Feng, Liang Hu, Liang Wang, Fan Lu, Meixiao Shen
Purpose: To investigate the retinal vascular network alterations in highly myopic eyes. Methods: Thirty-three highly myopic eyes from 21 subjects and 47 mildly myopic or emmetropic eyes from 24 healthy control subjects were enrolled. Optical coherence tomography angiography (OCTA) was used to image the superficial, deep, and whole retinal vascular plexuses at the macular region. Highly myopic eye images were analyzed after adjusting the ocular magnification using Bennett's formula...
November 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27818207/validation-of-guidelines-for-undercorrection-of-intra-ocular-lens-iol-power-in-children
#19
Virender Sachdeva, Sushma Katukuri, Ramesh Kekunnaya, Merle Fernandes, Mohammed Hasnat Ali
INTRODUCTION: Initial undercorrection of intra-ocular lens (IOL power) is a common practice in children undergoing pediatric cataract surgery. However, long term refractive status of these children is largely unknown. The purpose of this study is to analyze the long-term refractive status of these children. DESIGN: Retrospective observational study METHODS: We analyzed records of children (< 7 yrs) who underwent cataract surgery where a primary IOL implantation was performed and had completed follow-up upto atleast 7 years of age...
November 3, 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/27818204/retinal-microvascular-network-and-microcirculation-assessments-in-high-myopia
#20
Min Li, Ye Yang, Hong Jiang, Giovanni Gregori, Luiz Roisman, Fang Zheng, Bilian Ke, Dongyi Qu, Jianhua Wang
PURPOSE: To investigate the changes of the retinal microvascular network and microcirculation in high myopia. DESIGN: A cross-sectional, matched, comparative clinical study. PARTICIPANTS: Twenty eyes of twenty subjects with non-pathological high myopia (28 ± 5 Years) with a refractive error of -6.31 ± 1.23 Diopters (mean ± standard deviation) and twenty eyes of twenty age- and gender-matched control subjects (30 ± 6 years) with a refractive error of -1...
November 3, 2016: American Journal of Ophthalmology
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