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Embodiment

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https://www.readbyqxmd.com/read/28530128/in-vivo-endocrine-secretion-of-prostacyclin-following-expression-of-a-cox-1-pgis-fusion-protein-in-the-salivary-glands-of-rats-via-non-viral-gene-therapy
#1
Zhimin Wang, Raymond L Benza, Lee Zourelias, Angela Sanguino, Ramaz Geguchadze, Kelly J Shields, Changgong Wu, Kristin B Highland, Michael J Passineau
Pulmonary arterial hypertension is a progressive disease that culminates in right heart failure and death. Prostacyclin(PGI2) and its derivatives are effective treatments for PAH when administered as continuous parenteral infusions. This treatment paradigm requires medical sophistication, and patients are at risk for complications from an indewelling catheter; drug interruptions may result in rebound pulmonary hypertension and death. We hypothesized that the salivary gland can be repurposed into an endogenous production site for circulating PGI2 through the expression of a fusion protein embodying cyclooxygenase-1(Cox1) and prostacyclin synthase(PGIS) domains...
May 20, 2017: Human Gene Therapy
https://www.readbyqxmd.com/read/28529234/-in-utter-fearlessness-of-the-reigning-disease-imagined-immunities-and-the-outbreak-narratives-of-charles-brockden-brown
#2
Nicholas E Miller
With an increased focus on the intersection of literature and medicine, contagion has become something of a scholarly buzzword in early American studies: it serves metaphorically to demarcate the postcolonial other, demonstrates the transmissibility of revolutionary rhetoric, highlights the instability of republican government, and embodies fears of racial mixture. In this essay, I shift the emphasis from a discourse of contagion (often associated with a fear of the foreign) to a discourse of immunity (a fear associated with foreign immunities) in order to demonstrate a more affirmative biopolitics in Charles Brockden Brown's 1790s outbreak narratives...
2017: Literature and Medicine
https://www.readbyqxmd.com/read/28527327/nursing-work-and-sensory-experiences-of-hospital-design-a-before-and-after-qualitative-study-following-a-move-to-all-single-room-inpatient-accommodation
#3
S Donetto, C Penfold, J Anderson, G Robert, J Maben
The embodied experience of nursing practice is rarely studied. Drawing on data from an internationally relevant larger study conducted in 2013-14, here we explore the sensory dimension of the embodied experiences of nursing staff working on two acute NHS hospital wards before and after a move to all-single room inpatient accommodation. We undertook a secondary analysis of 25 interviews with nursing staff (12 before and 13 after the move with half [13/25] using photographs taken by participants) from a mixed-method before-and-after study...
May 17, 2017: Health & Place
https://www.readbyqxmd.com/read/28525782/the-performativity-of-numbers-in-illness-management-the-case-of-swedish-rheumatology
#4
Anna Essén, Eivor Oborn
While there is a proliferation of numerical data in healthcare, little attention has been paid to the role of numbers in constituting the healthcare reality they are intended to depict. This study explores the performativity of numbers in the microlevel management of rheumatoid disease. We draw on a study of patients' and physicians' use of the numbers in the Swedish Rheumatology Quality Registry, conducted between 2009 and 2014. We show how the numbers performed by constructing the disease across time, and by framing action...
May 10, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28525781/sleep-waves-and-recovery-from-drug-and-alcohol-dependence-towards-a-rhythm-analysis-of-sleep-in-residential-treatment
#5
Robert Meadows, Sarah Nettleton, Joanne Neale
This paper reports on a study of sleep amongst men and women who are living in residential rehabilitation centres in the UK and who are receiving support for their recovery from addiction to alcohol and other forms of substance use. Conceptually and methodologically, the paper draws on the work of the French sociologist Lefebvre and, in particular, his rhythmanalysis. We argue that this approach offers a useful way of exploring sleep in terms of biological, experiential, temporal, spatial and social rhythms...
May 6, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28523984/christopher-eccleston-embodied-the-psychology-of-physical-sensation-eccleston-christopher-embodied-the-psychology-of-physical-sensation-oxford-uk-oxford-university-press-2016-271-pp-isbn-9780198727903-%C3%A2-29-99-paperback
#6
https://www.readbyqxmd.com/read/28522968/the-effect-of-visual-spatial-and-temporal-manipulations-on-embodiment-and-action
#7
Natasha Ratcliffe, Roger Newport
The feeling of owning and controlling the body relies on the integration and interpretation of sensory input from multiple sources with respect to existing representations of the bodily self. Illusion paradigms involving multisensory manipulations have demonstrated that while the senses of ownership and agency are strongly related, these two components of bodily experience may be dissociable and differentially affected by alterations to sensory input. Importantly, however, much of the current literature has focused on the application of sensory manipulations to external objects or virtual representations of the self that are visually incongruent with the viewer's own body and which are not part of the existing body representation...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28521007/computing-the-social-brain-connectome-across-systems-and-states
#8
Daniel Alcalá-López, Jonathan Smallwood, Elizabeth Jefferies, Frank Van Overwalle, Kai Vogeley, Rogier B Mars, Bruce I Turetsky, Angela R Laird, Peter T Fox, Simon B Eickhoff, Danilo Bzdok
Social skills probably emerge from the interaction between different neural processing levels. However, social neuroscience is fragmented into highly specialized, rarely cross-referenced topics. The present study attempts a systematic reconciliation by deriving a social brain definition from neural activity meta-analyses on social-cognitive capacities. The social brain was characterized by meta-analytic connectivity modeling evaluating coactivation in task-focused brain states and physiological fluctuations evaluating correlations in task-free brain states...
May 18, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28517983/personalised-medicine-and-the-economy-of-biotechnological-promise
#9
Steve Sturdy
Rather than seek to distinguish hype from legitimate promise, it may be more helpful to think about personalised medicine as embodying a promissory economy which serves both to mobilize resources for research and - partly at least - to determine the ends to which that research is directed. Personalised medicine is a development of the larger promissory economy of medical biotechnology. As such, it systematically conflates public benefit with the pursuit of commercial and especially pharmaceutical interests...
April 2017: New Bioethics: a Multidisciplinary Journal of Biotechnology and the Body
https://www.readbyqxmd.com/read/28514873/unpacking-community-mobility-a-preliminary-study-into-the-embodied-experiences-of-stroke-survivors
#10
Christa S Nanninga, Louise Meijering, Klaas Postema, Marleen C Schönherr, Ant T Lettinga
PURPOSE: To enrich the discussion on mobility in stroke rehabilitation by translating theoretical repertoires of mobility from the context of geography to rehabilitation. METHOD: Qualitative research methodology was applied, and included in-depth interviews with stroke survivors. RESULTS: This study revealed: (a) social and material differences in clinical, private and public places; (b) ambivalences and shifting tensions in bodily, family and community life; (c) differences in access to resources to be used for mobility...
May 17, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28514788/embodied-pain-grasping-a-thorny-problem
#11
Michael K Nicholas, Claire Ashton-James
No abstract text is available yet for this article.
June 2017: Pain
https://www.readbyqxmd.com/read/28514384/-innovative-endoscopic-technologies-in-multi-field-medical-facility
#12
O E Karpov, P S Vetshev, A S Maady, K I Alekseev, A S Osipov, I V Vasiliev
The modern clinical practice is characterized by intensive introduction of innovative technologies for improving treatment and diagnostic procedures, minimizing their impact on the patient, complications rate and economic reasons. One of the priorities in this area is both diagnostic and therapeutic endoscopy. The degree of practical use of innovative endoscopic technologies depends on not only the quality of care, but also their economic reasons. Endoscopic treatment has become the method of choice for gastrointestional bleeding, extraction of foreign bodies, obstructive jaundice, polyps of the gastrointestinal tract, achalasia, esophageal strictures, etc...
2017: Khirurgiia
https://www.readbyqxmd.com/read/28513203/automating-the-incremental-evolution-of-controllers-for-physical-robots
#13
Andrés Faíña, Lars Toft Jacobsen, Sebastian Risi
Evolutionary robotics is challenged with some key problems that must be solved, or at least mitigated extensively, before it can fulfill some of its promises to deliver highly autonomous and adaptive robots. The reality gap and the ability to transfer phenotypes from simulation to reality constitute one such problem. Another lies in the embodiment of the evolutionary processes, which links to the first, but focuses on how evolution can act on real agents and occur independently from simulation, that is, going from being, as Eiben, Kernbach, & Haasdijk [2012, p...
May 17, 2017: Artificial Life
https://www.readbyqxmd.com/read/28513182/-it-just-opens-up-their-world-autism-empathy-and-the-therapeutic-effects-of-equine-interactions
#14
Roslyn Malcolm, Stefan Ecks, Martyn Pickersgill
Experiences of autism-spectrum disorder are now increasingly studied by social scientists. Human-animal relations have also become a major focus of social inquiry in recent years. Examining horse-assisted therapy for autistic spectrum disorders, this is the first paper that brings these fields together. Drawing on participant observation and interviews at a UK horse therapy Centre, this article examines how staff and the parents of riders account for the successes and limitations of equine therapy. To the respondents, horses 'open up' autistic children and make possible interactions that seemed impossible before...
May 17, 2017: Anthropology & Medicine
https://www.readbyqxmd.com/read/28509654/clinical-reasoning-embodied-meaning-making-in-physiotherapy
#15
Anoop Chowdhury, Wenche Schrøder Bjorbækmo
This article examines physiotherapists' lived experience of practicing physiotherapy in primary care, focusing on clinical reasoning and decision-making in the case of a patient we call Eva. The material presented derives from a larger study involving two women participants, both with a protracted history of neck and shoulder pain. A total of eight sessions, all of them conducted by the first author, a professional physiotherapist, in his own practice room, were videotaped, after which the first author transcribed the sessions and added reflective notes...
May 16, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/28506123/jack-d-a-mobile-social-networking-application-and-gender-performance-a-site-of-exclusion-within-a-site-of-inclusion
#16
Michael D Bartone
User-generated smartphone applications have created a new level of virtual connectivity for gay males, one in which users can create profiles and meet other users as nearby or as faraway as possible. For those within close proximity, the other users can be considered their "virtual neighbors." While the applications are theoretically designed to be places of inclusion and not exclusion, where any gay male with economic means can download an application, many profiles have been created, which exclude other users...
May 16, 2017: Journal of Homosexuality
https://www.readbyqxmd.com/read/28502406/steering-the-conversation-a-linguistic-exploration-of-natural-language-interactions-with-a-digital-assistant-during-simulated-driving
#17
David R Large, Leigh Clark, Annie Quandt, Gary Burnett, Lee Skrypchuk
Given the proliferation of 'intelligent' and 'socially-aware' digital assistants embodying everyday mobile technology - and the undeniable logic that utilising voice-activated controls and interfaces in cars reduces the visual and manual distraction of interacting with in-vehicle devices - it appears inevitable that next generation vehicles will be embodied by digital assistants and utilise spoken language as a method of interaction. From a design perspective, defining the language and interaction style that a digital driving assistant should adopt is contingent on the role that they play within the social fabric and context in which they are situated...
September 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28501552/taking-turns-across-channels-conversation-analytic-tools-in-animal-communication
#18
REVIEW
Marlen Fröhlich
To advance bridging the gulf between the fields of linguistics and animal communication, interest has recently been drawn to turn-taking behaviour in social interaction. While vocal turn-taking is the major form of conservational language usage in humans, recent studies on great apes has shown that they engage in a bodily form, gestural turn-taking, to achieve mutual communicative goals. However, most studies on turn-taking behaviour neglected the fact that signals are perceived and produced in a multimodal format...
May 10, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28497113/toward-a-cure-does-host-immunity-play-a-role
#19
Jielin Zhang, Clyde S Crumpacker
Three decades of research on human immunodeficiency virus (HIV) and AIDS reveal that the human body has developed through evolution a genome immune system embodying epigenetic regulation against pathogenic nucleic acid invasion. In HIV infection, this epigenetic regulation plays a cardinal role in HIV RNA production that silences HIV transcription at a molecular (RNA) level, controls viral load at a cellular (biological) level, and governs the viremic stage of AIDS at the clinical (patient) level. Even though the human genome is largely similar among humans and HIV is a single viral species, human hosts show significant differences in viral RNA levels, ranging from cell to organ to individual and expressed as elite controllers, posttreatment controllers, and patients with AIDS...
March 2017: MSphere
https://www.readbyqxmd.com/read/28495391/engaging-women-with-an-embodied-conversational-agent-to-deliver-mindfulness-and-lifestyle-recommendations-a-feasibility-randomized-control-trial
#20
Paula M Gardiner, Kelly D McCue, Lily M Negash, Teresa Cheng, Laura F White, Leanne Yinusa-Nyahkoon, Brian W Jack, Timothy W Bickmore
OBJECTIVE: This randomized controlled trial evaluates the feasibility of using an Embodied Conversational Agent (ECA) to teach lifestyle modifications to urban women. METHODS: Women were randomized to either 1) an ECA (content included: mindfulness, stress management, physical activity, and healthy eating) or 2) patient education sheets mirroring same content plus a meditation CD/MP3 once a day for one month. General outcome measures included: number of stress management techniques used, physical activity levels, and eating patterns...
April 26, 2017: Patient Education and Counseling
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