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https://www.readbyqxmd.com/read/29772064/impact-of-inter-patient-variability-on-organ-dose-estimates-according-to-mird-schema-uncertainty-and-variance-based-sensitivity-analysis
#1
Alexandra Zvereva, Florian Kamp, Helmut Schlattl, Maria Zankl, Katia Parodi
PURPOSE: Variance-based sensitivity analysis (SA) is described and applied to the radiation dosimetry model proposed by the Committee on Medical Internal Radiation Dose (MIRD) for the organ-level absorbed dose calculations in nuclear medicine. The uncertainties in the dose coefficients thus calculated are also evaluated. METHODS: A Monte Carlo approach was used to compute first-order and total-effect SA indices, which rank the input factors according to their influence on the uncertainty in the output organ doses...
May 17, 2018: Medical Physics
https://www.readbyqxmd.com/read/29746907/oscillatory-networks-of-high-level-mental-alignment-a-perspective-taking-meg-study
#2
R A Seymour, H Wang, G Rippon, K Kessler
Mentally imagining another's perspective is a high-level social process, reliant on manipulating internal representations of the self in an embodied manner. Recently Wang et al. (2016) showed that theta-band (3-7Hz) brain oscillations within the right temporo-parietal junction (rTPJ) and brain regions coding for motor/body schema contribute to the process of perspective-taking. Using a similar paradigm, we set out to unravel the extended functional brain network in detail. Increasing the angle between self and other perspective was accompanied by longer reaction times and increases in theta power within rTPJ, right lateral pre-frontal cortex (PFC) and right anterior cingulate cortex (ACC)...
May 7, 2018: NeuroImage
https://www.readbyqxmd.com/read/29624596/embodied-pain-in-fibromyalgia-disturbed-somatorepresentations-and-increased-plasticity-of-the-body-schema
#3
Endika Martínez, Zigor Aira, Itsaso Buesa, Ibane Aizpurua, Diego Rada, Jon Jatsu Azkue
Fibromyalgia syndrome (FMS) is a highly prevalent, chronic musculoskeletal condition characterized by widespread pain and evoked pain at tender points. This study evaluated various aspects of body awareness in a sample of 14 women with FMS and 13 healthy controls, such as plasticity of the body schema, body esteem, and interoceptive awareness. To this end, the Rubber Hand Illusion (RHI), the Body Esteem Scale (BES), and the Body Perception Questionnaire (BPQ) were used, respectively. Consistent with increased plasticity of the body schema, FMS patients scored higher, with large or very large effect sizes, across all three domains evaluated in the RHI paradigm, namely proprioceptive drift and perceived ownership and motor control over the rubber hand...
2018: PloS One
https://www.readbyqxmd.com/read/29567546/body-image-related-negative-interpretation-bias-in-anorexia-nervosa
#4
Timo Brockmeyer, Alisa Anderle, Hagen Schmidt, Stephanie Febry, Wally Wünsch-Leiteritz, Andreas Leiteritz, Hans-Christoph Friederich
A distorted body image and pronounced body dissatisfaction are hallmarks of anorexia nervosa (AN) that typically result in dietary restraint and compensatory behaviours. Cognitive biases such as negative interpretation bias are considered key maintaining factors of these maladaptive cognitions and behaviours. However, little attention has been paid to empirical tests whether negative interpretation bias exists in AN and to what degree it is associated with symptom severity. Participants in the present study were 40 women with AN and 40 healthy women with no history of an eating disorder...
March 14, 2018: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/29557815/shame-and-defectiveness-beliefs-in-treatment-seeking-patients-with-body-dysmorphic-disorder
#5
Hilary Weingarden, Ashley M Shaw, Katharine A Phillips, Sabine Wilhelm
Shame is a distressing emotion experienced when individuals judge themselves in a broadly negative and critical manner. Clinical descriptions of body dysmorphic disorder (BDD) emphasize the centrality of shame, yet research on shame in BDD remains scarce. This study is the largest investigation of shame in clinically diagnosed individuals with BDD, and it is the first to examine whether shame changes with treatment. Eighty-three adults with BDD were treated with 14 weeks of open-label escitalopram. Shame was measured using the Young Schema Questionnaire-Short Form...
March 19, 2018: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/29504685/imagining-with-the-body-in-analytical-psychology-movement-as-active-imagination-an-interdisciplinary-perspective-from-philosophy-and-neuroscience
#6
Ana Deligiannis
This article explores how the body and imagination operate as pathways of knowledge through the use of Movement as Active Imagination in clinical practice. This method activates the transcendent function, thus encouraging new therapeutic responses. A philosophical perspective (Spinoza, Nietzsche, Merleau-Ponty) and some concepts from neuroscience (embodied cognition, somatic markers, image schema, mirror neurons, neuronal plasticity) will accompany us throughout this work, illustrated with a clinical vignette...
April 2018: Journal of Analytical Psychology
https://www.readbyqxmd.com/read/29499580/-body-schema-multisensory-integration-and-developmental-disorders
#7
Annika Reinersmann, Thomas Lücke
Our body is both, the object experiencing the world and the subject of our self- experience. As an object, the body provides sensory information via the bodily surface, which is processed and integrated into a coherent representation of the body, the body schema. This representation is considered to form a crucial structure underlying bodily self-identification. The process of integrating multimodal information into a coherent body representation has received extensive research interest with the aim to further clarify its neuronal correlates and functioning in health and disease...
April 2018: Fortschritte der Neurologie-Psychiatrie
https://www.readbyqxmd.com/read/29485300/space-perception-movement-and-insight-attuning-to-the-space-of-everyday-life-after-major-weight-loss
#8
Eli Natvik, Karen Synne Groven, Målfrid Råheim, Eva Gjengedal, Shaun Gallagher
Physiotherapists are well placed to help people adjust and engage meaningfully with the world following major weight loss. Recent research indicates that the body size a patient has lived with for years can continue to affect movement and perception even after largescale weight loss. This article explores this discrepancy in depth from the perspective of phenomenology and space perception and through the concepts of body image, body schema, and affordances. It draws on an empirical example in which a nautical engineer described his lived experience of returning to work following bariatric surgery and the discrepancies he experienced while adjusting to his new situation, particularly when moving his smaller body around the ship's engine room, previously inaccessible to him...
February 27, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29469020/changes-in-nutritional-state-and-dysphagia-in-stroke-patients-monitored-during-a-14-d-period-in-a-burkina-faso-hospital-setting
#9
Jeoffray Diendéré, Athanase Millogo, Pierre-Marie Preux, Pierre Jésus, Jean-Claude Desport
INTRODUCTION: Dysphagia and undernourishment are common in cerebrovascular accident (stroke) patients in developed countries. Despite the dietary transition, there is little information available in Africa on this topic. This study aims to assess the prevalence of undernourishment and dysphagia in stroke patients in two Burkina Faso teaching hospitals at a starting point (D0), on the eighth day, and on the 14th (D14) and to specify factors related to undernourishment at day 14. METHODOLOGY: The nutritional state of the patients was assessed using body mass index, triceps skinfold thickness, and mid-upper arm circumference...
April 2018: Nutrition
https://www.readbyqxmd.com/read/29433958/an-ontology-driven-clinical-decision-support-system-iddap-for-infectious-disease-diagnosis-and-antibiotic-prescription
#10
Ying Shen, Kaiqi Yuan, Daoyuan Chen, Joël Colloc, Min Yang, Yaliang Li, Kai Lei
BACKGROUND: The available antibiotic decision-making systems were developed from a physician's perspective. However, because infectious diseases are common, many patients desire access to knowledge via a search engine. Although the use of antibiotics should, in principle, be subject to a doctor's advice, many patients take them without authorization, and some people cannot easily or rapidly consult a doctor. In such cases, a reliable antibiotic prescription support system is needed. METHODS AND RESULTS: This study describes the construction and optimization of the sensitivity and specificity of a decision support system named IDDAP, which is based on ontologies for infectious disease diagnosis and antibiotic therapy...
March 2018: Artificial Intelligence in Medicine
https://www.readbyqxmd.com/read/29430771/factors-associated-with-romantic-relationship-formation-difficulties-in-women-with-breast-cancer
#11
L-K Shaw, K A Sherman, J Fitness, E Elder
OBJECTIVE: Many un-partnered women report difficulty in forming romantic relationships after breast cancer, characterized by high dating-related anxiety and low perceived interpersonal competence. This study examined the relationship between poor body image (appearance investment and body dissatisfaction) and self-compassion, and women's ability to form romantic relationships post-breast cancer. METHODS: Women (N = 152) diagnosed with breast cancer, who were either un-partnered and expressed interest in romantic dating, or who had commenced a relationship post-diagnosis, completed an online survey...
April 2018: Psycho-oncology
https://www.readbyqxmd.com/read/29427866/laterality-recognition-of-images-motor-performance-and-aspects-related-to-pain-in-participants-with-and-without-wrist-hand-disorders-an-observational-cross-sectional-study
#12
René Pelletier, Johanne Higgins, Daniel Bourbonnais
OBJECTIVE: Musculoskeletal disorders are associated with altered sensory, proprioceptive and cognitive processes. Sensory processes affect the internal cortical representation of the body in space, the body schema, which in turn influences motor control. The purpose of this study was to determine if participants with wrist/hand disorders had impaired performance on a task associated with the body schema, the Left/Right Judgement Task (LRJT) and secondly how LRJT performance, motor performance, disability, pain and related aspects are associated...
June 2018: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/29371410/intra-individual-comparison-of-tc-99m-mdp-bone-scan-and-the-psma-ligand-tc-99m-mip-1427-in-patients-with-osseous-metastasized-prostate-cancer
#13
Hendrik Rathke, Ali Afshar-Oromieh, Frederik L Giesel, Christophe Kremer, Paul Flechsig, Sabine Haufe, Walter Mier, Tim Holland-Letz, Maximilian de Bucourt, Thomas Armor, John Babich, Uwe Haberkorn, Clemens Kratochwil
To evaluate the detection rate of bone metastases obtained with the PSMA targeting tracer 99m Tc-MIP-1427 as opposed to the conventional bone scan with 99m Tc-MDP in a collective of advanced stage patients with known osseous metastasized prostate cancer. Methods: 21 Patients with known metastatic disease were staged with both, conventional bone scan and PSMA-ligand scintigraphy, within a time-frame of <10 days. Imaging included planar whole-body scans and SPECT or SPECT/CT with two bed positions 3 h after injection of either 500-750 MBq 99m Tc-MIP-1427 or 600-750 MBq 99m Tc-MDP...
January 25, 2018: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29371141/the-impact-of-childhood-sexual-abuse-on-women-s-sexual-health-a-comprehensive-review
#14
REVIEW
Carey S Pulverman, Chelsea D Kilimnik, Cindy M Meston
INTRODUCTION: Childhood sexual abuse (CSA) has been identified as a potent risk factor for sexual dysfunction. Certain characteristics of the abuse experience, such as repeated abuse, appear to affect the risk of developing sexual dysfunction. Despite the robust findings that CSA can be detrimental to sexual function, there is little consensus on the exact mechanisms that lead to these difficulties. AIM: To summarize the most up-to-date research on the relation between CSA and women's sexual function...
April 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29362698/attentional-biases-toward-body-images-in-males-at-high-risk-of-muscle-dysmorphia
#15
Xinhong Jin, Yahong Jin, Shi Zhou, Shun-Nan Yang, Shuzhi Chang, Hui Li
Objective: Although research on muscle dysmorphia (MD), a body dysmorphic disorder subtype, has recently increased, the causes and mechanisms underlying this disorder remain unclear. Results from studies examining disorders associated with body image suggest the involvement of self-schema in biasing attention toward specific body information. The present study examined whether individuals at higher risk of MD also display attentional biases toward specific types of body images. Methods: The validated Chinese version of the Muscle Appearance Satisfaction Scale was used to distinguish men at higher and lower risk of MD...
2018: PeerJ
https://www.readbyqxmd.com/read/29356610/restoring-body-image-after-cancer-rebic-results-of-a-randomized-controlled-trial
#16
Mary Jane Esplen, Jiahui Wong, Ellen Warner, Brenda Toner
Purpose This study aimed to test a group psychosocial intervention focused on improving disturbances of body image (BI), sexual functioning, and quality of life in breast cancer (BC) survivors. Methods A prospective, randomized controlled trial was conducted to assess the efficacy of an 8-week group intervention in women after BC treatment. The manual-based intervention combined two powerful ingredients: expressive guided-imagery exercises integrated within a model of group-therapy principles. The intervention facilitates exploration of identity, the development of new self-schemas, and personal growth...
March 10, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29282089/evaluation-of-a-software-module-for-adaptive-treatment-planning-and-re-irradiation
#17
Anne Richter, Stefan Weick, Thomas Krieger, Florian Exner, Sonja Kellner, Bülent Polat, Michael Flentje
BACKGROUND: The aim of this work is to validate the Dynamic Planning Module in terms of usability and acceptance in the treatment planning workflow. METHODS: The Dynamic Planning Module was used for decision making whether a plan adaptation was necessary within one course of radiation therapy. The Module was also used for patients scheduled for re-irradiation to estimate the dose in the pretreated region and calculate the accumulated dose to critical organs at risk...
December 28, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/29272995/primary-care-challenges-of-an-obscure-case-of-alice-in-wonderland-syndrome-in-a-patient-with-severe-malaria-in-a-resource-constrained-setting-a-case-report
#18
Benjamin Momo Kadia, Cyril Jabea Ekabe, Ettamba Agborndip
BACKGROUND: "Alice in Wonderland" syndrome (AIWS) is a rare neurological abnormality characterized by distortions of visual perceptions, body schema and experience of time. AIWS has been reported in patients with various infections such as infectious mononucleosis, H1N1 influenza, Cytomegalovirus encephalitis, and typhoid encephalopathy. However, AIWS occurring in a patient with severe malaria is less familiar and could pose serious primary care challenges in a low-income context...
December 22, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29226463/which-limb-is-it-responses-to-vibrotactile-stimulation-in-early-infancy
#19
Eszter Somogyi, Lisa Jacquey, Tobias Heed, Matej Hoffmann, Jeffrey J Lockman, Lionel Granjon, Jacqueline Fagard, J Kevin O'Regan
This study focuses on how the body schema develops during the first months of life, by investigating infants' motor responses to localized vibrotactile stimulation on their limbs. Vibrotactile stimulation was provided by small buzzers that were attached to the infants' four limbs one at a time. Four age groups were compared cross-sectionally (3-, 4-, 5-, and 6-month-olds). We show that before they actually reach for the buzzer, which, according to previous studies, occurs around 7-8 months of age, infants demonstrate emerging knowledge about their body's configuration by producing specific movement patterns associated with the stimulated body area...
December 11, 2017: British Journal of Developmental Psychology
https://www.readbyqxmd.com/read/29201910/body-schema-illusions-a-study-of-the-link-between-the-rubber-hand-and-kinesthetic-mirror-illusions-through-individual-differences
#20
Morgane Metral, Corentin Gonthier, Marion Luyat, Michel Guerraz
Background: The well-known rubber hand paradigm induces an illusion by having participants feel the touch applied to a fake hand. In parallel, the kinesthetic mirror illusion elicits illusions of movement by moving the reflection of a participant's arm. Experimental manipulation of sensory inputs leads to emergence of these multisensory illusions. There are strong conceptual similarities between these two illusions, suggesting that they rely on the same neurophysiological mechanisms, but this relationship has never been investigated...
2017: BioMed Research International
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