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https://www.readbyqxmd.com/read/28087492/multi-antibiotic-resistant-and-putative-virulence-gene-signatures-in-enterococcus-species-isolated-from-pig-farms-environment
#1
Abeni Beshiru, Isoken H Igbinosa, Faith I Omeje, Abraham G Ogofure, Martin M Eyong, Etinosa O Igbinosa
The continuous misuse of antimicrobials in food animals both orally and subcutaneously as therapeutic and prophylactic agents to bacterial infections could be detrimental and contribute to the dissemination of resistant clones in livestock production. The present study was carried out to determine the antibiogram and virulence gene characteristics of Enterococcus species from pig farms. A total of 300 faecal samples were obtained from two pig farms in Benin City between February and July, 2016. Standard culture-based and polymerase chain reaction (PCR) assay were adopted in the detection and characterization of the Enterococcus species...
January 10, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28075032/-microbiological-findings-and-antibacterial-therapy-in-stevens-johnson-syndrome-toxic-epidermal-necrolysis-patients-from-a-swedish-burn-center
#2
Ilaria Tocco-Tussardi, Fredrik Huss, Benjamin Presman
BACKGROUND: Superimposed infections/sepsis are the major cause of morbidity/mortality in Stevens-Johnson syndrome/Toxic Epidermal Necrolysis (SJS/TEN). It is a delicate balance between avoiding new pharmaceuticals and prophylactically treat an incipient infection. The objective of this study was to investigate the rates and types of infection-microbials and antibiotics involved in SJS/TEN patients. METHODS: Microbiology and clinical data were collected for SJS/TEN patients admitted to our Burn Centre from January 2010 through January 2016...
January 11, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28072612/prophylactic-antibiotics-for-enucleation-and-evisceration-a-retrospective-study-and-systematic-literature-review
#3
Brett Pariseau, Barry Fox, Jonathan Dutton
PURPOSE: To report surgical site infection (SSI) rates of eviscerations and enucleations with implants performed without perioperative intravenous (IV) antibiotics or postoperative oral antibiotics, and to give SSI prevention recommendations. METHODS: A single-center retrospective chart review was performed after obtaining institutional review board approval. Charts were found by Current Procedural Terminology codes. Demographics, surgical indication, procedure, implant, antibiotic use, and postoperative course were recorded...
January 6, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28071948/current-practice-of-antibiotic-prophylaxis-during-elective-laparoscopic-cholecystectomy
#4
Caw Macano, E A Griffiths, R S Vohra
INTRODUCTION Current guidelines do not recommend antibiotic prophylaxis in elective laparoscopic cholecystectomy. Despite this, there is wide variation in antibiotic prophylaxis during cholecystectomy in population-based studies. The aim of this survey was to establish the current rationale for antibiotic prophylaxis in elective laparoscopic cholecystectomy. METHODS A short questionnaire was designed and disseminated across collaborators for a population-based study investigating outcomes following cholecystectomy and via the Association of Upper Gastrointestinal Surgeons, Researchgate and Surginet membership...
January 10, 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/28071145/bacteriophages-and-their-derivatives-for-the-treatment-and-control-of-food-producing-animal-infections
#5
Carla Carvalho, Ana Rita Costa, Filipe Silva, Ana Oliveira
Nowadays, the world is facing an increasing emergence of antibiotic resistant bacteria. Simultaneously, the banning of some existing antibiotics and the lack of development of new antimicrobials have created an urgent need to find new alternatives against animal infections. Bacteriophages (phages) are naturally occurring predators of bacteria, ubiquitous in the environment, with high host specificity and harmless to animals. For these reasons, phages and their derivatives are being considered valuable antimicrobial alternatives and an opportunity to reduce the current use of antibiotics in agri-food production, increasing animal productivity and providing environmental protection...
January 10, 2017: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/28067086/-prospective-randomized-study-regarding-the-effect-of-the-preoperative-antibiotic-and-chlorhexidine-rinse-on-wound-healing-after-mandibular-third-molar-surgery
#6
István Kaposvári, Kinga Körmöczi, Zsuzsa Beáta László, Ferenc Oberna, Ferenc Horváth, Árpád Joób-Fancsaly
INTRODUCTION AND AIM: The study compares the antibiotic prophylaxis combined with postoperative antibiotic therapy to preoperative chlorhexidine rinse combined with postoperative antibiotic therapy in preventing complications after surgical removal of a mandibular third molar. METHOD: 71 healthy patients in four groups were enrolled in the study: I. prophylactic dose of 2000 mg of amoxicillin clavulanate, continued with amoxicillin clavulanate postoperatively; II...
January 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28063606/-assessment-of-antibiotic-use-and-impact-of-an-intervention-intended-to-modify-the-prescribing-behavior-in-surgical-prophylaxis-in-6hospitals-in-the-metropolitan-area-of-monterrey-mexico
#7
Gerardo Del Carmen Palacios-Saucedo, Mauricio de la Garza-Camargo, Evangelina Briones-Lara, Sandra Carmona-González, Ricardo García-Cabello, Luis Arturo Islas-Esparza, Gustavo Saldaña-Flores, Juan Roberto González-Cano, Román González-Ruvalcaba, Francisco Javier Valadez-Botello, Gerardo Enrique Muñoz-Maldonado, Carlos Alberto Montero-Cantú, Rita Delia Díaz-Ramos, Fortino Solórzano-Santos
BACKGROUND: Improper use of antibiotics increases antimicrobial resistance. OBJECTIVE: Evaluate the use of antibiotics and the impact of an intervention designed to improve antibiotic prescription for surgical prophylaxis in 6 hospitals of Monterrey, Mexico. MATERIAL AND METHODS: Design: A prospective multicenter survey and a pretest-postest experimental study. Phase 1: Survey to evaluate the use of antibiotics through an especially designed guide...
January 4, 2017: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/28063174/oral-supplementation-of-trans-cinnamaldehyde-reduces-uropathogenic-escherichia-coli-colonization-in-a-mouse-model
#8
Amoolya Narayanan, Muhammed Shafeekh Muyyarikkandy, Shankumar Mooyottu, Kumar Venkitanarayanan, Mary Anne Roshni Amalaradjou
Urinary tract infections (UTIs) in the United States result in more than 7 million hospital visits per year. Uropathogenic E. coli (UPEC) is responsible for more than 80% of UTIs. Although antibiotics are the drug of choice to control UTIs, their repeated use has resulted in the emergence of antibiotic resistant UPEC. Thus, there is a need for effective alternate strategies to control UPEC infections. This study investigated the efficacy of trans-cinnamaldehye (TC), a food-grade molecule present in cinnamon, in reducing UPEC colonization and pathogenesis in the lower UTI...
January 7, 2017: Letters in Applied Microbiology
https://www.readbyqxmd.com/read/28060097/assessment-of-nasal-carriage-of-staphylococcus-aureus-and-axillar-flora-in-patients-with-acromegaly
#9
Ramazan Gen, Elif Şahin Horasan, Ümit Çinkir, Kerem Sezer, Esen Akbay
PURPOSE: Recent study showed that patients with acromegaly have typical skin findings including increased sebum secretion, decreased transepidermal water loss, more alkaline, and colder skin surface correlated with serum growth hormone and insulin-like growth factor 1 levels. Different anatomic localizations and texture of the skin differ in bacterial concentrations.Nasal carriage of Staphylococcus aureus and axillar flora in patients with acromegaly was compared with normal population with regard to duration of acromegaly as well as the growth hormone and insulin-like growth factor 1 levels...
January 5, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28054929/rare-complication-of-stomas-peristomal-necrotizing-fasciitis
#10
Kivanc Derya Peker, Burak M Ilhan
INTRODUCTION: A stoma formation is a frequently performed procedure in patients undergoing colorectal surgery. Although stoma formation is a simple process, it should be performed with caution. The aim of this study was to attract physicians' attention to this rare disease and also to identify the surgical and medical treatment options for peristomal necrotizing fasciitis as a rare complication. MATERIALS AND METHODS: Risk factors including age, sex, additional diseases, previous surgical procedures, source of infection, physical findings, and vital signs of 14 patients with peristomal necrotizing fasciitis over a period of 10 years from 2005 to 2015 were retrospectively evaluated...
December 2016: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/28051247/supplementation-with-high-titer-cranberry-extract-anthocran%C3%A2-for-the-prevention-of-recurrent-urinary-tract-infections-in-elderly-men-suffering-from-moderate-prostatic-hyperplasia-a-pilot-study
#11
A Ledda, G Belcaro, M Dugall, B Feragalli, A Riva, S Togni, L Giacomelli
OBJECTIVE: Recently, cranberry extracts have been tested as a nutritional supplementation in the prevention of lower urinary tract symptoms (LUTS) as well as recurrent urinary tract infections (UTIs) in subjects at risk, with mixed results. However, evidence of efficacy should be considered only for well-characterized and standardized products in a more selected study population. Moreover, the efficacy of these interventions in elderly must be further investigated. The aim of this pilot, registry study was to evaluate the prophylactic effects of an oral supplementation containing a highly concentrated and standardized cranberry extract reproducing the natural total profile of cranberry fruits, in elderly men with benign prostatic hyperplasia (BPH), suffering from recurrent UTIs, over a 2-months follow-up...
December 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28050817/phosphatidylcholine-coatings-deliver-local-antimicrobials-and-reduce-infection-in-a-murine-model-a-preliminary-study
#12
Michael A Harris, Karen E Beenken, Mark S Smeltzer, Warren O Haggard, J Amber Jennings
BACKGROUND: Phosphatidylcholine coatings have been shown to elute antibiotics for several days. A recently developed biofilm inhibitor, cis-2-decenoic acid (C2DA), has been shown to exhibit synergistic activity with several common antibiotics. This study aims to evaluate the effectiveness of C2DA and amikacin dual drug delivery from a phosphatidylcholine coating. QUESTIONS/PURPOSES: (1) What are the in vitro elution profiles of amikacin and C2DA from phosphatidylcholine-coated coupons in incubated phosphate-buffered saline? (2) Does the presence of C2DA in eluate samples lower the amount of amikacin needed for bacterial inhibition in overnight bacterial turbidity assays? (3) Does addition of amikacin and C2DA result in decreased colony-forming units (CFUs) on wire implants and bone when compared with phosphatidylcholine coatings alone in a mouse model of periprosthetic joint infection? METHODS: Effects of loading concentrations were assessed during 7-day in vitro elution studies for coatings containing all mixtures of 0%, 5%, 15%, and 25% wt of amikacin and C2DA (n = 4) through quantitative high-performance liquid chromatography concentration determination and plotting concentration eluted over time...
January 3, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28043507/t-cell-cytokine-responses-in-peripheral-blood-mononuclear-cells-from-patients-with-multidrug-resistant-tuberculosis-following-stimulation-with-proteins-purified-from-mycobacterium-tuberculosis-mdr-clinical-isolates
#13
Alireza Hadizadeh Tasbiti, Shamsi Yari, Mostafa Ghanei, Seyed Davar Siadat, Amir Amanzadeh, Payam Tabarsi, Keyvan Saeedfar, Ahmadreza Bahrmand
OBJECTIVE: Tuberculosis (TB) is a devastating disease that remains a major health threat worldwide. The appearance of Mycobacterium tuberculosis strains resistance to current antibiotics is a growing problem, both in the third world and in developed countries. Completion of genomic sequencing of M. tuberculosis provides a strong foundation for subsequent identification of proteins to aid the understanding of protein function and the discovery of new drug targets or a TB vaccine. This study employed a proteomics approach to identify proteins from antibiotic resistant M...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28042365/variations-in-strategies-to-prevent-ventriculostomy-related-infections-a-practice-survey
#14
Ariane Lewis, Barry M Czeisler, Aaron S Lord
BACKGROUND AND PURPOSE: The ideal strategy to prevent infections in patients with external ventricular drains (EVDs) is unclear. METHODS: We conducted a cross-sectional survey of members of the Neurocritical Care Society on infection prevention practices for patients with EVDs between April and July 2015. RESULTS: The survey was completed by 52 individuals (5% response rate). Catheter selection, use of prolonged prophylactic systemic antibiotics (PPSAs), cerebrospinal fluid (CSF) collection policies, location of EVD placement, and performance of routine EVD exchanges varied...
January 2017: Neurohospitalist
https://www.readbyqxmd.com/read/28042262/dentists-knowledge-and-practice-regarding-prevention-of-infective-endocarditis
#15
Soukaina Ryalat, Yazan Hassona, Mohammad Al-Shayyab, Mais Abo-Ghosh, Faleh Sawair
OBJECTIVES: The objective of this study is to assess the knowledge and practice of dentists from Jordan, regarding prevention of infective endocarditis (IE) in dental practice. MATERIALS AND METHODS: A sample of Jordanian dentists was interviewed regarding their IE knowledge and practice using a validated and pretested survey instrument. RESULTS: Most of the dentists have encountered a patient with IE who needed prophylactic antibiotic (PA) and have prescribed antibiotics to prevent IE...
October 2016: European Journal of Dentistry
https://www.readbyqxmd.com/read/28029082/probiotics-in-curing-allergic-and-inflammatory-conditions-research-progress-and-futuristic-vision
#16
Kuldeep Dhama, Shyma K Latheef, Ashok Kumar Munjal, Rekha Khandia, Hari Abdul Samad, Hafiz M N Iqbal, Sunil K Joshi
BACKGROUND: Probiotics constitute the viable and beneficial microbes, which offer a dietary means to sustain the balance of gastro-intestinal (GI) microflora. Owing to their multiple health benefits, these have recently gained wide attention among researchers for exploring their potential in safeguarding the health of humans and animals. Probiotics could also modulate host-immune responses, thereby help in counteracting the immunological dysfunctions. Probiotics can inhibit the systemic invasion of pathogens entering through the GI mucosa/ oral cavity and have been found to possess effective prophylactic and therapeutic utilities against various infectious pathogens as well as non-infectious diseases and disorders...
December 26, 2016: Recent Patents on Inflammation & Allergy Drug Discovery
https://www.readbyqxmd.com/read/28025009/peri-operative-care-for-patients-undergoing-lymphaticovenular-anastomosis-a-systematic-review
#17
REVIEW
Harm Winters, Hanneke J P Tielemans, Philippe N Sprangers, Dietmar J O Ulrich
BACKGROUND: Lymphaticovenular anastomosis (LVA) is a supermicrosurgical procedure that involves the anastomosis of a functional lymphatic channel to a venule. Although peri-operative care might be an important contributor to the success of this technique, evidence about optimal peri-operative care seems limited. This review aims to summarize the peri-operative methods used by authors reporting on LVA. METHODS: A systematic search of the literature was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines...
November 27, 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28012329/total-hip-arthroplasty-for-femoral-neck-fracture-with-pyoderma-gangrenosum-patient-a-case-report
#18
Guo Rong She, Jun Yuan Chen, Zi Qi Zhou, Zhen Gang Zha, Ning Liu
INTRODUCTION: Pyoderma gangrenosum is a rare inflammatory aseptic, ulcerative neutrophilic dermatosis which manifest as skin recurrent, painful ulcers. PRESENTATION OF CASE: A 65-year-old man with pyoderma gangrenosum underwent left total hip arthroplasty because of femoral neck fractures. Glucocorticoid, antibiotic, anticoagulant drug, etc. were given in perioperative period. Complication of pyoderma gangrenosum was prevented successfully in perioperative period...
December 9, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28011997/do-salivary-bypass-tubes-lower-the-incidence-of-pharyngocutaneous-fistula-following-total-laryngectomy-a-retrospective-analysis-of-predictive-factors-using-multivariate-analysis
#19
Robert W A Hone, Eqramur Rahman, Gentle Wong, Yvette Annan, Victoria Alexander, Ali Al-Lami, Kiran Varadharajan, Michael Parker, Ricard Simo, Lisa Pitkin, Alasdair Mace, Enyinnaya Ofo, Alistair Balfour, Iain J Nixon
Salivary bypass tubes (SBT) are increasingly used to prevent pharyngocutaneous fistula (PCF) following laryngectomy and pharyngolaryngectomy. There is minimal evidence as to their efficacy and literature is limited. The aim of the study was to determine if SBT prevent PCF. The study was a multicentre retrospective case control series (level of evidence 3b). Patients who underwent laryngectomy or pharyngolaryngectomy for cancer or following cancer treatment between 2011 and 2014 were included in the study...
December 23, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28007104/dose-and-administration-of-intracameral-moxifloxacin-for-prophylaxis-of-postoperative-endophthalmitis
#20
Steve A Arshinoff, Milad Modabber
PURPOSE: To review current and past practices of intracameral antibiotic administration for infection prophylaxis in cataract surgery; to review the benefits and liabilities of available prophylactic drugs, dosage determination, and administration protocols; and to devise an optimum dose and administration protocol for intracameral moxifloxacin. SETTING: Humber River Hospital and the University of Toronto, Toronto, Ontario, Canada. DESIGN: Retrospective evaluation of treatment modality...
December 2016: Journal of Cataract and Refractive Surgery
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