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https://www.readbyqxmd.com/read/28226419/evaluation-of-risk-factors-for-clostridium-difficile-infection-in-hematopoietic-stem-cell-transplant-recipients
#1
Tonya L Scardina, Elena Kang Martinez, Neelam Balasubramanian, Mary Fox-Geiman, Scott E Smith, Jorge P Parada
STUDY OBJECTIVES: The primary objective was to determine the impact of hematologic malignancies and/or conditioning regimens on the risk of developing Clostridium difficile infection (CDI) in patients undergoing hematopoietic stem cell transplantation (HSCT). Secondary objectives were to determine if traditional CDI risk factors applied to patients undergoing HSCT and to determine the presence of CDI markers of severity of illness among this patient population. DESIGN: Single-center, retrospective, case-control study...
February 22, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28222946/is-the-intake-of-selective-serotonin-reuptake-inhibitors-associated-with-an-increased-risk-of-dental-implant-failure
#2
B R Chrcanovic, J Kisch, T Albrektsson, A Wennerberg
The aim of this retrospective study was to investigate the association between the intake of selective serotonin reuptake inhibitors (SSRIs) and the risk of dental implant failure. Patients were included if they were taking SSRIs only and no other medication, did not present any other systemic condition or compromising habits (bruxism, smoking, snuff), and complied with the use of prophylactic antibiotics for implant surgery. The multivariate generalized estimating equation (GEE) method and multilevel mixed-effects parametric survival analysis were used to test the association between SSRI exposure (predictor variable) and the risk of implant failure (outcome variable), adjusting for several potential confounders (other variables)...
February 17, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28221851/virulence-of-trypanosoma-cruzi-in-a%C3%A3-ai-euterpe-oleraceae-martius-pulp-following-mild-heat-treatment
#3
Rodrigo Labello Barbosa, Karen Signori Pereira, Viviane Liotti Dias, Flávio Luis Schmidt, Delma Pegolo Alves, Ana Maria Aparecida Guaraldo, Luiz Augusto Corrêa Passos
Outbreaks of acute Chagas disease (ACD) in northern Brazil can be caused by the ingestion of unprocessed açai pulp contaminated with Trypanosoma cruzi . The aim of this study was to determine the minimum thermal process required to inactivate T. cruzi in açai pulp. Trypomastigotes (100,000) of T. cruzi Y strain were added to 0.15 M NaCl or açai pulp and continuously mixed while being heat treated at 37 to 49°C for up to 1 h. When necessary, parasites were separated from açai pulp by forced sieving. Inocula were administrated intraperitoneally in inbred immunodeficient C...
October 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28220309/transseptal-suturing-technique-in-septoplasty-impact-on-bacteremia-and-nosocomial-colonization
#4
Onur Ismi, Cengiz Ozcan, Yusuf Vayısoğlu, Candan Öztürk, Sebahat Aslan Tek, Kemal Görür
Although effects of Merocel(®) nasal packs and silicone splints on nasal flora alterations and bacteremia formation after septoplasty were assessed before, the effect of transseptal suturing technique has not been studied yet. The objective of this study is to compare nasal flora alterations and bacteremia occurrence rates between Merocel packs, silicone splints, and transseptal suturing technique in septoplasty. Ninety patients were divided into three groups randomly: Merocel packing (Group M), silicone splint (Group S), and transseptal suturing without packing (Group T)...
February 20, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28218999/assessment-of-morbidity-and-mortality-associated-with-eus-guided-fna-for-pancreatic-cystic-lesions-a-system-review-and-meta-analysis
#5
REVIEW
Huiyun Zhu, Fei Jiang, Jianwei Zhu, Yiqi Du, Zhendong Jin, Zhaoshen Li
BACKGROUND AND AIM: With increased availability of imaging technology, detection of pancreatic cystic lesions (PCLs) is on the rise. Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) improves the diagnosis accuracy of PCLs. Systematic evaluation of morbidity and mortality associated with EUS-FNA for PCLs has not been performed. We conducted a systematic review and meta-analysis of morbidity and mortality associated with EUS-FNA. METHODS: A literature search for relevant English-language articles was conducted on PubMed and EMBASE databases...
February 20, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28215612/postoperative-infections-after-excision-of-neurogenic-heterotopic-ossifications-at-the-hip-risk-factors-and-causative-organisms
#6
L Gatin, F Genêt, A Dinh, P Denormandie
BACKGROUND: Neurogenic heterotopic ossification (NHO) is usually treated by surgical excision. Post-operativeinfection (POI) is a possible complication, whose epidemiology, causative organisms, and risk factors are poorly known.We therefore conducted a case-control study to 1) identify the risk factors for POI after surgical excision of NHO at the hip, 2) determine the frequency of POI, 3) and identify the causative organisms. HYPOTHESIS: Risk factors for POI after NHO excision at the hip can be identified...
February 16, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28213455/question-2-does-prophylactic-nystatin-prevent-invasive-fungal-infections-in-immunocompetent-critically-ill-children-on-broad-spectrum-antibiotics
#7
Matthew Beake, James Fraser
No abstract text is available yet for this article.
March 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28212436/antibody-deficiency-in-patients-with-frequent-exacerbations-of-chronic-obstructive-pulmonary-disease-copd
#8
Brian N McCullagh, Alejandro P Comellas, Zuhair K Ballas, John D Newell, M Bridget Zimmerman, Antoine E Azar
Chronic Obstructive Pulmonary Disease is the third leading cause of death in the US, and is associated with periodic exacerbations, which account for the largest proportion of health care utilization, and lead to significant morbidity, mortality, and worsening lung function. A subset of patients with COPD have frequent exacerbations, occurring 2 or more times per year. Despite many interventions to reduce COPD exacerbations, there is a significant lack of knowledge in regards to their mechanisms and predisposing factors...
2017: PloS One
https://www.readbyqxmd.com/read/28210086/prognostic-factors-associated-with-mortality-in-patients-with-gastric-fundal-variceal-bleeding
#9
Keishi Komori, Masaru Kubokawa, Eikichi Ihara, Kazuya Akahoshi, Kazuhiko Nakamura, Kenta Motomura, Akihide Masumoto
AIM: To determine the prognostic factors associated with mortality in patients with gastric fundal variceal (GFV) bleeding. METHODS: In total, 42 patients were endoscopically diagnosed with GFV bleeding from January 2000 to March 2014. We retrospectively reviewed the patients' medical records and assessed their history, etiology of liver cirrhosis, disease conditions, treatment options for GFV bleeding, medications administered before and after onset of GFV bleeding, blood test results (hemoglobin, albumin, and bilirubin concentrations), and imaging results (including computed tomography and abdominal ultrasonography)...
January 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28199275/assessing-the-cost-of-prophylactic-antibiotic-use-after-cleft-lip-and-lip-adhesion-procedures
#10
Kimberly M Daniels, Michael D Lappi, Susan Flath Sporn, Catherine Noonan Caillouette, Ronald Heald, John G Meara
The purpose of this study was to understand the true cost of administering prophylactic antibiotics postoperatively to patients undergoing cleft lip and lip adhesion procedures for which the rate of infection is historically low. Using time-driven activity-based costing (TDABC) methodologies, the plastic surgery department of one hospital created a process map with related time intervals and personnel cost rates for administering the antibiotic. The cost for each provider, based on standard salary information, was multiplied by the time required to complete his or her stage of the process, and this outcome was added to the supply costs...
July 2016: Journal of Healthcare Management / American College of Healthcare Executives
https://www.readbyqxmd.com/read/28197380/the-influence-of-gut-decontamination-prophylactic-antibiotics-on-acute-graft-versus-host-disease-and-survival-following-allogeneic-hematopoietic-stem-cell-transplantation
#11
Bertrand Routy, Caroline Letendre, David Enot, Maxime Chénard-Poirier, Vikram Mehraj, Noémie Charbonneau Séguin, Khaled Guenda, Kathia Gagnon, Paul-Louis Woerther, David Ghez, Silvy Lachance
The intestinal microbiota plays a key role in the pathogenesis of acute graft-versus-host disease (aGVHD). High-dose conditioning regimens given prior to allogeneic hematopoietic stem cell transplantation (aHSCT) modulate the composition of gut microbiota and damage the gut epithelial barrier, resulting in increased systemic inflammation. We assessed whether gut decontamination with antibiotics (ATB) prior to aHSCT influenced the frequency of aGVHD and mortality in 500 patients from two Canadian centers between 2005 and 2012...
2017: Oncoimmunology
https://www.readbyqxmd.com/read/28195985/prosthetic-joint-infections-in-patients-undergoing-carpal-tunnel-release
#12
Wenjing Zeng, Deborah Paul, Thomas Kemp, John Elfar
INTRODUCTION: Little information is available regarding the rate of prosthetic joint infections (PJIs) in patients undergoing carpal tunnel release (CTR) without antibiotic prophylaxis. Hand surgeons should be aware of patients' history of arthroplasty. METHODS: All patients who underwent CTR at our institution between 2012 and 2014 were identified and their charts were reviewed to identify those who had a history of total hip, knee, and/or shoulder arthroplasty...
March 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28192644/perioperative-antibiotics-for-prevention-of-acute-endophthalmitis-after-cataract-surgery
#13
REVIEW
Emily W Gower, Kristina Lindsley, Samantha E Tulenko, Afshan A Nanji, Ilya Leyngold, Peter J McDonnell
BACKGROUND: Endophthalmitis is a severe inflammation of the anterior or posterior (or both) chambers of the eye that may be sterile or associated with infection. It is a potentially vision-threatening complication of cataract surgery. Prophylactic measures for endophthalmitis are targeted against various sources of infection. OBJECTIVES: To evaluate the effects of perioperative antibiotic prophylaxis for endophthalmitis following cataract surgery compared with no prophylaxis or other form of prophylaxis...
February 13, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28190612/-long-term-infectious-risks-after-splenectomy-a-retrospective-cohort-study-with-up-to-10-years-follow-up
#14
E Meriglier, M Puyade, M Carretier, F Roblot, P Roblot
INTRODUCTION: Although most infections occur within the first 2 years after splenectomy, the relatively short follow-up reported in many studies may underestimate the frequency of infections. The objective of the study was to determine the incidence of infective outcomes and factors associated with infection after splenectomy by studying a group of patients who underwent splenectomy over a 10-year period. METHODS: A retrospective and monocentric study of patients who underwent splenectomy between January 1st, 1997 and December 31st, 2004 in a French university hospital...
February 9, 2017: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/28188364/a-survey-of-pulmonary-arteriovenous-malformation-screening-management-and-follow-up-in-hereditary-hemorrhagic-telangiectasia-centers-of-excellence
#15
Jeffrey Forris Beecham Chick, Shilpa N Reddy, Reed E Pyeritz, Scott O Trerotola
PURPOSE: To determine current practice regarding screening, management, and follow-up of pulmonary arteriovenous malformations (PAVMs), particularly those with feeding arteries <3 mm in diameter, in those patients with hereditary hemorrhagic telangiectasia (HHT) at HHT Centers of Excellence. MATERIALS AND METHODS: A 32-question survey focusing on PAVM screening, management, and follow-up was sent to 147 participants at HHT Centers worldwide. RESULTS: Thirty-three responses were received (22%); 60% from interventional radiologists and 20% from pulmonologists; 67% from the USA, 21% European, and 6% Asian...
February 10, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28182174/eye-injuries-from-pencil-lead-three-cases
#16
Ceyhun Arıcı, Osman Şevki Arslan, Burcu Görgülü, Rengin Yıldırım, Umut Onur
Corneal stromal and/or penetrating ocular injuries from pencils and pencil lead are more common in childhood and may lead to intraocular infection or severe intraocular sterile inflammatory reaction. Herein we report 3 children with ocular trauma due to pencil lead injuries. The first case had corneal stromal injury caused by a pencil. In the second case, a pencil perforated the cornea and contacted the iris. In the third case, pencil lead perforated both the cornea and iris and reached the vitreous through the lens zonules...
January 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28179620/effectiveness-of-antibiotic-use-management-in-tianjin-2011-2013-a-quasi-experimental-study
#17
Hai-Hong Zhang, Yue Du, Wei Liu, Shi-Duo Song, Wen Zhao, Guo-Wei Huang, He-Sheng Wang
BACKGROUND In this study we investigated changes in the status of antibiotic use in Tianjin since the implementation of the Antibiotic Stewardship Program (ASP) (2011-2013), as well as existing problems, strategies, and outcomes to promote rational clinical antibiotic use. MATERIAL AND METHODS A quasi-experimental study was performed to investigate situations of antibiotic use in secondary and tertiary general hospitals in Tianjin from April 2011 to 2013. Five major indicators were analyzed: percentage of antibiotic use in inpatient cases (%), antibacterial use density (AUD), proportion of prophylactic antibiotic application for type I surgical incision, compliance rate of medication administration 0...
February 9, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28163520/penetrating-anterior-skull-base-fracture-inflicted-by-a-cow-s-horn
#18
Adomas Bunevicius, Karolis Bareikis, Laimutis Kalasauskas, Arimantas Tamasauskas
Farm workers are at increased risk for animal-inflicted head injuries that are associated with significant morbidity and occasionally may be fatal. These injuries may cause permanent eye damage with or without concomitant skull base fracture. Here, we present a male farmer who suffered a cow attack that resulted in perforating orbital injury with comminuted frontobasal cranial fracture caused by a cow's horn. The next day, the patient developed nasal and orbital cerebrospinal fluid (CSF) leak. Computed Tomography cisternography revealed CSF leakage to frontal and maxillary sinuses...
December 2016: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28162966/over-the-counter-antibiotics-in-saudi-arabia-an-urgent-call-for-policy-makers
#19
Sharafaldeen Bin Nafisah, Salahaldin Bin Nafesa, Aliyah H Alamery, Mazen A Alhumaid, Haitham M AlMuhaidib, Fahad A Al-Eidan
Antibiotics over-consumption is a pandemic that has a tremendous cost on the overwhelmed healthcare system. The accessibility of antibiotics coupled with the misconception of public toward those drugs both of which implicated in the use and misuse of antibiotics. The aim of this study was to investigate the perception of the community toward antibiotics, its purpose and harmfulness, in addition to the accessibility of those drugs as over the counter and without prescriptions. We also investigated the behavior toward antibiotic prescriptions when perceived unnecessary...
February 2, 2017: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/28161927/optimal-duration-for-the-use-of-0-5-levofloxacineye-drops-before-vitreoretinal-surgery
#20
Xiaoxin Li, Xiaoling Liang, Luosheng Tang, Junjun Zhang, Lijun Shen, Guanfang Su, Xiaorong Li
PURPOSE: To investigate various regimens of prophylactic antibiotic therapy for vitreoretinal surgery. DESIGN: This study compared different prophylactic therapies with 0.5% levofloxacin eye drops. METHODS: Two hundred nine patients from 7 hospitals scheduled to undergo vitreoretinal surgery were randomized into 3 groups to receive 0.5% levofloxacin eye drops for 1 day (6 times/d), 2 days (3 times/d), or 3 days (3 times/d) before surgery (groups 1D, 2D, and 3D, respectively)...
January 2017: Asia-Pacific Journal of Ophthalmology
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