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https://www.readbyqxmd.com/read/28530591/optimization-of-an-organic-yogurt-based-on-sensorial-nutritional-and-functional-perspectives
#1
Ariadne Roberto Karnopp, Katherine Guimarães Oliveira, Eriel Forville de Andrade, Bruna Mara Postingher, Daniel Granato
The effects of purple grape juice (PGJ), grape skin flour (GSF), and oligofructose (OLI) on proximate composition, total phenolic content (TPC), antioxidant activity (AA), sensory, physicochemical, and textural properties of yogurts were analyzed using response surface methodology. Multiple regression models were proposed and results showed that PGJ increased the viscosity, AA, and TPC, while GSF increased the ash and total fiber contents of yogurts. GSF and OLI increased the hardness and consistency. A simultaneous optimization was performed to maximize TPC, ash and fibers contents, and sensory acceptance: a yogurt containing 1...
October 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28528097/protein-digestomic-analysis-reveals-the-bioactivity-of-deer-antler-velvet-in-simulated-gastrointestinal-digestion
#2
Yang Yu, Yan Jin, Fangjun Wang, Jiaze Yan, Yanxia Qi, Mingliang Ye
Proteins are the most prominent bioactive component in deer antler velvet. The aim of the present study was to track the fate of protein of antler velvet by protein digestomics. The peptide profile identified by LC-MS/MS and the in vitro bioactivity of antler velvet aqueous extract (AAE) were investigated in simulated gastrointestinal digestion. A total of 23, 387 and 417 peptides in AAE, gastric and pancreatic digests were identified using LC-MS/MS, respectively. Collagens, the predominant proteins, released 34 peptides in gastric digests and 146 peptides in pancreatic digests...
June 2017: Food Research International
https://www.readbyqxmd.com/read/28521835/adult-autoimmune-enteropathy-presenting-initially-with-acquired-acrodermatitis-enteropathica-a-case-report
#3
Erina Lie, Sarah Sung, Steven Hoseong Yang
BACKGROUND: Acrodermatitis enteropathica (AE) is a rare dermatitis secondary to zinc deficiency most commonly seen as an inherited disease in infants. In the last decade, increased number of reports have been published on the acquired form that presents in adulthood. Unlike its inherited counterpart, acquired AE (AAE) is often secondary to underlying pathologic or iatrogenic etiologies that interfere with nutritional absorption, such as inflammatory bowel disease or alcoholism. Various gastrointestinal pathologies have been associated with AAE, but there is currently no report on its association with adult autoimmune enteropathy (AIE), a rare gastrointestinal disorder commonly seen in infants, with limited cases reported in adults...
May 18, 2017: BMC Dermatology
https://www.readbyqxmd.com/read/28493955/molecular-diversity-analysis-drought-related-marker-traits-association-mapping-and-discovery-of-excellent-alleles-for-100-day-old-plants-by-est-ssrs-in-cassava-germplasms-manihot-esculenta-cranz
#4
Bin Wang, Xin Guo, Pingjuan Zhao, Mengbin Ruan, Xiaoling Yu, Liangping Zou, Yiling Yang, Xiao Li, Deli Deng, Jixiang Xiao, Yiwei Xiao, Chunji Hu, Xue Wang, Xiaolin Wang, Wenquan Wang, Ming Peng
Cassava is the third largest food crop of the world and has strong ability of drought tolerance. In order to evaluate the molecular diversity and to discover novel alleles for drought tolerance in cassava germplasms, we examined a total of 107 abiotic stress related expressed sequence tags-simple sequence repeat (EST-SSR) markers in 134 cassava genotypes coming from planting regions worldwide and performed drought related marker-traits association mapping. As results, we successfully amplified 98 of 107 markers in 97 polymorphic loci and 279 alleles, with 2...
2017: PloS One
https://www.readbyqxmd.com/read/28458157/anti-inflammatory-and-anti-oxidant-effects-of-cardamom-elettaria-repens-sonn-baill-and-its-phytochemical-analysis-by-4d-gcxgc-tof-ms
#5
Hemanth Kumar Kandikattu, P Rachitha, G V Jayashree, K Krupashree, M Sukhith, Abdul Majid, Narayanappa Amruta, Farhath Khanum
Elleteria repens is a large cardamom used in the culinary preparations. In the present study, we have evaluated in vitro antioxidant and free radical scavenging activities E. repens hexane extract (ERH) exhibited DPPH and metal chelating activity with IC50 values of 464±28.3μg/ml, 199±7.2μg/ml whereas the reducing power and antioxidant activities are found to be 289±14.6 AAE/mg, 468±22.7 GAE/mg. The observed antioxidant activities could be correlated with metabolites such as polyphenol, flavonoid, and terpenoid group of compounds identified in hexane fraction of E...
April 27, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28454566/apoptosis-induced-effects-of-extract-from-artemisia-annua-linn%C3%A3-by-modulating-pten-p53-pdk1-akt-signal-pathways-through-pten-p53-independent-manner-in-hct116-colon-cancer-cells
#6
Eun Ji Kim, Guen Tae Kim, Bo Min Kim, Eun Gyeong Lim, Sang-Yong Kim, Young Min Kim
BACKGROUND: The extracts from Artemisia annua Linné (AAE) has been known to possess various functions including anti-bacterial, anti-virus and anti-oxidant effects. However, the mechanism of those effects of AAE is not well known. Pursuantly, we determined the apoptotic effects of extract of AAE in HCT116 cell. In this study, we suggested that AAE may exert cancer cell apoptosis through PTEN/PDK1/Akt/p53signal pathway and mitochondria-mediated apoptotic proteins. METHODS: We measured 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, lactate dehydrogenase (LDH) assay, Hoechst 33342 staining, Annexin V-PI staining, Mitopotential assay, immunofluorescence (IF) and Western blotting...
April 28, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28453259/direct-in-situ-mass-specific-absorption-spectra-of-biomass-burning-particles-generated-from-smoldering-hard-and-softwoods
#7
James G Radney, Rian You, Michael R Zachariah, Christopher D Zangmeister
Particles from smoldering biomass burning (BB) represent a major source of carbonaceous aerosol in the terrestrial atmosphere. In this study, mass specific absorption spectra of laboratory-generated smoldering wood particles (SWP) from 3 hardwood and 3 softwood species were measured in situ. Absorption data spanning from λ = 500 to 840 nm were collected using a photoacoustic spectrometer coupled to a supercontinuum laser with a tunable wavelength and bandwidth filter. SWP were size- (electrical mobility) and mass-selected prior to optical characterization allowing data to be reported as mass-specific absorption cross sections (MAC)...
May 4, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28446201/anticonvulsant-effects-of-antiaris-toxicaria-aqueous-extract-investigation-using-animal-models-of-temporal-lobe-epilepsy
#8
Priscilla Kolibea Mante, Donatus Wewura Adongo, Eric Woode
BACKGROUND: Antiaris toxicaria has previously shown anticonvulsant activity in acute animal models of epilepsy. The aqueous extract (AAE) was further investigated for activity in kindling with pentylenetetrazole and administration of pilocarpine and kainic acid which mimic temporal lobe epilepsy in various animal species. RESULTS: ICR mice and Sprague-Dawley rats were pre-treated with AAE (200-800 mg kg(-1)) and convulsive episodes induced using pentylenetetrazole, pilocarpine and kainic acid...
April 26, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28437266/gelfoam-interposition-minimizes-risk-of-fistula-and-postoperative-bleeding-in-modified-furlow-palatoplasty
#9
Jing Li, Patrick A Gerety, James Johnston, Jesse A Taylor
Failure to accomplish a tension-free, watertight closure predisposes the palatoplasty patient to fistula formation. Perioperative bleeding also places the patient at risk for adverse airway events (AAE). This study introduces the incorporation of a hemostatic gelatin sponge (Gelfoam) into layered palatoplasty to minimize adverse postoperative bleeding and fistula formation. A retrospective chart review was performed to identify subjects who underwent Furlow palatoplasty with insertion of Gelfoam from 2010 to 2015...
April 21, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28383798/survival-of-an-aggregatibacter-actinomycetemcomitans-quorum-sensing-luxs-mutant-in-the-mouths-of-rhesus-monkeys-insights-into-ecological-adaptation
#10
Senthil Kumar Velusamy, Vandana Sampathkumar, Dipti Godboley, Daniel H Fine
Experiments were designed to explore a prominent autoinducer-2 (AI-2) producing gene (luxS) related to colonization and survival of Aggregatibacter actinomycetemcomitans, a low abundance member of the indigenous flora, that forms a key component of the dysbiotic flora in localized aggressive periodontitis. The luxS gene was disrupted in a primate strain of A. actinomycetemcomitans prior to implantation into the oral cavity of Rhesus monkeys (Rh). The colonization efficiency of the luxS mutant (RhAa-VS4) was compared to the parental wild-type strain (RhAa3) (positive control) and a ltxA mutant (RhAa-VS2) (negative control)...
April 6, 2017: Molecular Oral Microbiology
https://www.readbyqxmd.com/read/28375142/crystal-structure-and-rna-binding-properties-of-an-hfq-homolog-from-the-deep-branching-aquificae-conservation-of-the-lateral-rna-binding-mode
#11
Kimberly A Stanek, Jennifer Patterson-West, Peter S Randolph, Cameron Mura
The host factor Hfq, as the bacterial branch of the Sm family, is an RNA-binding protein involved in the post-transcriptional regulation of mRNA expression and turnover. Hfq facilitates pairing between small regulatory RNAs (sRNAs) and their corresponding mRNA targets by binding both RNAs and bringing them into close proximity. Hfq homologs self-assemble into homo-hexameric rings with at least two distinct surfaces that bind RNA. Recently, another binding site, dubbed the `lateral rim', has been implicated in sRNA·mRNA annealing; the RNA-binding properties of this site appear to be rather subtle, and its degree of evolutionary conservation is unknown...
April 1, 2017: Acta Crystallographica. Section D, Structural Biology
https://www.readbyqxmd.com/read/28359331/in-vitro-antioxidant-and-%C3%AE-glucosidase-inhibitory-activities-and-comprehensive-metabolite-profiling-of-methanol-extract-and-its-fractions-from-clinacanthus-nutans
#12
Md Ariful Alam, I S M Zaidul, Kashif Ghafoor, F Sahena, M A Hakim, M Y Rafii, H M Abir, M F Bostanudin, V Perumal, A Khatib
BACKGROUND: This study was aimed to evaluate antioxidant and α-glucosidase inhibitory activity, with a subsequent analysis of total phenolic and total flavonoid content of methanol extract and its derived fractions from Clinacanthus nutans accompanied by comprehensive phytochemical profiling. METHODS: Liquid-liquid partition chromatography was used to separate methanolic extract to get hexane, ethyl acetate, butanol and residual aqueous fractions. The total antioxidant activity was determined by 2,2-diphenyl-1-picrylhydrazy (DPPH) radical scavenging and ferric reducing antioxidant power assay (FRAP)...
March 31, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28284781/diagnosis-course-and-management-of-angioedema-in-patients-with-acquired-c1-inhibitor-deficiency
#13
Andrea Zanichelli, Giulia Maria Azin, Maddalena Alessandra Wu, Chiara Suffritti, Lorena Maggioni, Sonia Caccia, Francesca Perego, Romualdo Vacchini, Marco Cicardi
BACKGROUND: Acquired angioedema due to C1-inhibitor deficiency (C1-INH-AAE) is a rare disease with no prevalence data or approved therapies. OBJECTIVE: To report data on patients with C1-INH-AAE followed at Angioedema Center, Milan (from 1976 to 2015). METHODS: Diagnostic criteria included history of recurrent angioedema without wheals; decreased C1-INH antigen levels and/or functional activity of C1-INH and C4 antigen less than 50% of normal; late symptom onset (>40 years); no family history of angioedema and C1-INH deficiency...
March 8, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28284114/spectral-dependence-of-aerosol-light-absorption-at-an-urban-and-a-remote-site-over-the-tibetan-plateau
#14
Chong-Shu Zhu, Jun-Ji Cao, Ta-Feng Hu, Zhen-Xing Shen, Xue-Xi Tie, Hong Huang, Qi-Yuan Wang, Ru-Jin Huang, Zhu-Zi Zhao, Griša Močnik, Anthony D A Hansen
We present a study of aerosol light absorption by using a 7-wavelength Aethalometer model AE33 at an urban site (Lhasa) and a remote site (Lulang) in the Tibetan Plateau. Approximately 5 times greater aerosol absorption values were observed at Lhasa (53±46Mm(-1) at 370nm and 20±18Mm(-1) at 950nm, respectively) in comparison to Lulang (15±19Mm(-1) at 370nm and 4±5Mm(-1) at 950nm, respectively). Black carbon (BC) was the dominant light absorbing aerosol component at all wavelengths. The brown carbon (BrC) absorption at 370nm is 32±15% of the total aerosol absorption at Lulang, whereas it is 8±6% at Lhasa...
March 8, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28284088/effect-of-the-micron-sized-silica-particles-mssp-on-biogas-conversion-of-sewage-sludge
#15
Xiaohu Dai, Ying Xu, Bin Dong
Micron-sized silica particles (MSSP), ranging from 3 μm to 50 μm, have been widely found in the sewage sludge. The inhibition of MSSP to biogas conversion of both excess sludge (ES) and model sludge (MS) are explored in this study. It is observed that with the effect of MSSP, the net cumulative methane production (NCMP) of ES and MS were decreased by 23.5% and 22.3%, respectively, and the apparent activation energy (AAE) of organic solubilisation of ES and MS were increased by 38.7% and 215%, respectively, which implies a crucial role for MSSP in anaerobic sludge digestion...
May 15, 2017: Water Research
https://www.readbyqxmd.com/read/28274230/appraisal-of-phytochemical-and-in-vitro-biological-attributes-of-an-unexplored-folklore-rhus-punjabensis-stewart
#16
Saira Tabassum, Madiha Ahmed, Bushra Mirza, Muhammad Naeem, Muhammad Zia, Zabta Khan Shanwari, Gul Majid Khan
BACKGROUND: The role of plants for discovery of therapeutic potential accentuates the need to know their biological attributes. The present study aims to comprehend the biological attributes of Rhus punjabensis, an unexplored traditional medicinal plant. METHODS: Leaf and stem extracts of R. punjabensis prepared in 11 different organic solvents are evaluated for multimode antioxidant potential, total phenolic and flavonoid contents were determined through colorimetric assays, HPLC-DAD analysis was carried out for quantification of various polyphenols in extracts...
March 9, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28265368/bioactivities-of-coturnix-japonica-quail-egg-yolk-and-albumen-against-physiological-stress
#17
Gideon O Oladipo, Emmanuel O Ibukun
Cold and immobilization stressors can generate oxidative stress as well as skeletal muscle fatigue. Free radicals cause oxidative degradation of lipids, proteins, nucleic acids, and carbohydrates molecules thereby compromising cell integrity and function. Coturnix japonica (quail) egg had been described as being very functional biochemically, due to the essential biomolecules it contains in very regulated quantity. This study was designed to evaluate the in vitro antioxidant activity of extracts of quail egg yolk and the albumen...
March 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28245729/seasonal-gender-and-regional-variations-in-total-phenolic-flavonoid-and-condensed-tannins-contents-and-in-antioxidant-properties-from-pistacia-atlantica-ssp-leaves
#18
Ziyad Ben Ahmed, Mohamed Yousfi, Johan Viaene, Bieke Dejaegher, Kristiaan Demeyer, Debby Mangelings, Yvan Vander Heyden
CONTEXT: The widespread use of Pistacia atlantica Desf. ssp. (Anacardiaceae) in traditional medicine can be partly attributed to the content of its secondary metabolites, in particular, the phenolic compounds. OBJECTIVE: The effects of harvest period, growing region and gender on the phenolic compounds, flavonoids and condensed tannins contents were studied, as well as on the antioxidant activities of P. atlantica leaves in order to provide a scientific basis for optimal collection...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28242942/a-comparative-overview-of-antioxidative-properties-and-phenolic-profiles-of-different-fungal-origins-fruiting-bodies-and-submerged-cultures-of-coprinus-comatus-and-coprinellus-truncorum
#19
Kristina Tešanović, Boris Pejin, Filip Šibul, Milan Matavulj, Milena Rašeta, Ljiljana Janjušević, Maja Karaman
Bioactive properties of fungi considerably differ between the fruiting body (FB) and the submerged culture as regards mycelia (M) and the fermentation broth (F). Antioxidant properties of hot-water extracts obtained from three different fungal origins: FB, M and F of two autochthonous fungal species (Northern Serbia), Coprinus comatus and Coprinellus truncorum were investigated. Free radical scavenging capacity (RSC) was evaluated in vitro by the DPPH assay and reducing power ability (FRAP assay). Considering possible bioactive properties of different compounds present in fungal extracts, the content of total proteins (TP), phenols (TC) and flavonoids (TF) were investigated colorimetrically...
February 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28222436/recurrent-angioedema-occurrence-features-and-concomitant-diseases-in-an-italian-single-center-study
#20
Paola Triggianese, Maria Domenica Guarino, Chiara Pellicano, Mauro Borzi, Elisabetta Greco, Stella Modica, Caterina De Carolis, Roberto Perricone
BACKGROUND: Angioedema (AE) is a potentially life-threatening condition with hereditary (HAE), acquired (AAE), or iatrogenic causes. A careful workup allows for the identification of the etiology of attacks and the appropriate management. In this cohort study, based on a clinical practice setting, we aimed at investigating clinical and laboratory findings concerning different features of patients with recurrent AE who were referred to a single, tertiary-level center for HAE. METHODS: Clinical and laboratory data of patients fulfilling the criteria for C1-inhibitor-deficient HAE (C1-INH-HAE), C1-INH-AAE, angiotensin-converting enzyme inhibitor-related AE (ACEI-RA), and idiopathic AAE (I-AAE) were evaluated...
2017: International Archives of Allergy and Immunology
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