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https://www.readbyqxmd.com/read/29137905/emergency-department-chest-radiography-for-children-with-asthma-exacerbation-is-infrequently-associated-with-change-of-management
#1
Evan H Allie, Henry E Dingle, William N Johnson, Jeffrey R Birnbaum, Melissa A Hilmes, Sudha P Singh, Donald H Arnold
BACKGROUND: Acute asthma exacerbations (AAE) account for many Pediatric Emergency Department (PED) visits. Chest radiography (CXR) is often performed in these patients to identify practice-changing findings such as pneumonia (PNA). Limited knowledge exists to balance the cost and radiation dose of CXR with expected yield of clinically meaningful information. OBJECTIVE: To determine in children with AAE with CXR, whether patient characteristics are associated with radiographic PNA; and significant practice change by initiation of antibiotic...
October 6, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29128878/microfracture-is-more-cost-effective-than-autologous-chondrocyte-implantation-a-review-of-level-1-and-level-2-studies-with-5%C3%A2-year-follow-up
#2
Tommy Frøseth Aae, Per-Henrik Randsborg, Hilde Lurås, Asbjørn Årøen, Øystein Bjerkestrand Lian
PURPOSE: Focal cartilage defects in the knee may have devastating effect on the knee joint, where two of the main surgical treatment options are microfracture and autologous chondrocyte implantation. Comparative studies have failed to establish which method yields the best clinical results. A cost-effectiveness analysis of microfracture and autologous chondrocyte implantation would contribute to the clinical decision process. METHODS: A PubMed search identifying level I and level II studies with 5 year follow-up was performed...
November 11, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29046012/root-aneurysm-following-aortic-valve-replacement-20-years-after-an-arterial-switch-operation
#3
Hikaru Ishii, Shigeyuki Aomi, Hideyuki Tomioka, Etsuji Umeda, Rihito Higashi, Kenji Yamazaki
Late development of annuloaortic ectasia (AAE) and progression of aortic regurgitation (AR) are widely recognized outcomes following an arterial switch operation (ASO). We treated a 29-year-old male with AAE and rapid aortic root expansion, who underwent ASO as a neonate and aortic valve replacement (AVR) as an adult. He was diagnosed as having dextro-(D-loop) transposition of the great arteries after birth and underwent ASO at the age of 13 months. At the age of 19 years, AVR was performed for progressive AR...
October 18, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/29039037/amaranth-seeds-amaranthus-palmeri-l-as-novel-feedstock-for-biodiesel-production-by-oleaginous-yeast
#4
Farha Deeba, Alok Patel, Neha Arora, Vikas Pruthi, Parul A Pruthi, Yuvraj S Negi
The potential of lipid accumulation by oleaginous yeast Cryptococcus vishniaccii grown on amaranth seed aqueous extract (AAE) media was assessed. Maximum cell biomass productivity of 104 mg/L/h, lipid productivity of 54 mg/L/h, and lipid content of 52.31% were recorded on AAE when carbon to nitrogen (C:N) ratio increased from 134 to 147 after removal of ammonia nitrogen. The lipid droplet (LD) size (2.32 ± 0.38 μm) was visualized by fluorescence microscopy using Nile red stain indicating maximum accumulated triacylglycerol (TAG) at C:N 147...
October 16, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29034570/efficacy-of-different-carriers-for-the-triple-antibiotic-powder-during-regenerative-endodontic-procedures
#5
David Hwang, Hanson Fong, James D Johnson, Avina Paranjpe
Chemical debridement during Regenerative Endodontic procedures is important. Previous research studies have evaluated various antibiotics and their concentrations but none have addressed the concern of delivering these materials. Hence, the purpose of this study was to determine what carrier could be used effectively in a clinical setting. Sixty caries-free maxillary incisors were used and inoculated with Enterococcus faecalis and divided into positive and irrigation controls and experimental groups that had triple antibiotic powder (1:1:1 ciprofloxacin:metronidazole:minocycline) delivered using various carriers: saline, cotton, sponge and methylcellulose...
October 16, 2017: Australian Endodontic Journal: the Journal of the Australian Society of Endodontology Inc
https://www.readbyqxmd.com/read/29034198/phenolic-constituents-and-modulatory-effects-of-raffia-palm-leaf-raphia-hookeri-extract-on-carbohydrate-hydrolyzing-enzymes-linked-to-type-2-diabetes
#6
Felix A Dada, Sunday I Oyeleye, Opeyemi B Ogunsuyi, Tosin A Olasehinde, Stephen A Adefegha, Ganiyu Oboh, Aline A Boligon
This study sought to investigate the effects of Raffia palm (Raphia hookeri) leaf extract on enzymes linked to type-2 diabetes mellitus (T2DM) and pro-oxidant induced oxidative stress in rat pancreas. The extract was prepared and its α-amylase and α-glucosidase inhibitory effects were determined. Radical [2,2-diphenyl-1-picrylhydrazyl (DPPH)] scavenging and Fe(2+)-chelating abilities, and inhibition of Fe(2+)-induced lipid peroxidation in rat pancreas homogenate were assessed. Furthermore, total phenol and flavonoid contents, reducing property, and high performance liquid chromatography diode array detector (HPLC-DAD) fingerprint of the extract were also determined...
October 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29027225/necroptotic-cell-death-in-anti-cancer-therapy
#7
REVIEW
Olga Krysko, Tania Løve Aaes, Valerian E Kagan, Katharina D'Herde, Claus Bachert, Luc Leybaert, Peter Vandenabeele, Dmitri V Krysko
Necroptosis is one the best-characterized forms of regulated necrosis. Necroptosis is mediated by the kinase activities of receptor interacting protein kinase-1 and receptor interacting protein kinase-3, which eventually lead to the activation of mixed lineage kinase domain-like. Necroptosis is characterized by rapid permeabilization of the plasma membrane, which is associated with the release of the cell content and subsequent exposure of damage-associated molecular patterns (DAMPs) and cytokines/chemokines...
November 2017: Immunological Reviews
https://www.readbyqxmd.com/read/28986069/accuracy-and-usefulness-of-aortic-annular-measurement-using-real-time-three-dimensional-transesophageal-echocardiography-comparison-with-direct-surgical-sizing
#8
Tomoko Nishi, Kentaro Shibayama, Minoru Tabata, Nahoko Kato, Masahiko Noguchi, Hiroshi Okumura, Yuji Kawano, Daisuke Nakatsuka, Kotaro Obunai, Yoshio Kobayashi, Hiroyuki Watanabe
BACKGROUND: There is a paucity of data that demonstrates a clinical impact of anatomical measurements of the aortic annulus by three-dimensional (3D) transesophageal echocardiography (TEE) on surgical aortic valve replacement (AVR). The aim of this study is to validate the accuracy of 3D TEE measurements compared with the direct intraoperative annular diameter and to investigate an impact of 3D TEE on a prediction of AVR with aortic annular enlargement (AAE). METHODS AND RESULTS: We retrospectively enrolled 61 patients who underwent both two-dimension (2D) and 3D TEE and transthoracic echocardiography (TTE) before AVR...
October 3, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28973102/how-african-american-english-speaking-first-graders-segment-and-rhyme-words-and-nonwords-with-final-consonant-clusters
#9
Amy J Shollenbarger, Gregory C Robinson, Valentina Taran, Seo-Eun Choi
Purpose: This study explored how typically developing 1st grade African American English (AAE) speakers differ from mainstream American English (MAE) speakers in the completion of 2 common phonological awareness tasks (rhyming and phoneme segmentation) when the stimulus items were consonant-vowel-consonant-consonant (CVCC) words and nonwords. Method: Forty-nine 1st graders met criteria for 2 dialect groups: AAE and MAE. Three conditions were tested in each rhyme and segmentation task: Real Words No Model, Real Words With a Model, and Nonwords With a Model...
September 22, 2017: Language, Speech, and Hearing Services in Schools
https://www.readbyqxmd.com/read/28901345/-acute-alcoholic-hepatitis
#10
Gianni Testino, Emanuele Scafato, Valentino Patussi
Chronic alcohol related liver disease is characterized by a cascade of events defined as follows: steatosis, steatohepatitis/steatofibrosi, cirrhosis and hepatocellular carcinoma. On one of these histologic patterns may overlap acute alcoholic hepatitis (AAE) (mild, moderate, severe). Severe AAE can cause a severe clinical picture: jaundice with a duration of less than three months, jaundice in the first decompensation event, serum bilirubin higher than 5 mg/dL, ratio AST/ALT >2:1, AST less than 500 IU/L ALT <300 IU/L, neutrophil leukocytosis and increased GGT...
September 2017: Recenti Progressi in Medicina
https://www.readbyqxmd.com/read/28873617/nutritional-and-bioactive-potential-of-myrtaceae-fruits-during-ripening
#11
Siluana Katia Tischer Seraglio, Mayara Schulz, Priscila Nehring, Fabiana Della Betta, Andressa Camargo Valese, Heitor Daguer, Luciano Valdemiro Gonzaga, Roseane Fett, Ana Carolina Oliveira Costa
This study aimed to characterize jabuticaba (Myrciaria cauliflora), guabiju (Myrcianthes pungens), and jambolan (Syzygium cumini) in relation to its individual phenolic compounds (LC-ESI-MS/MS), antioxidant capacity, total monomeric anthocyanin, sugars, and minerals during ripening (intermediate and ripe stages). In the three studied fruits, 22 phenolic compounds were quantified, especially phenolic acids and flavonoids, which presented a higher concentration in the intermediate ripening stage. In contrast, the total monomeric anthocyanin, fructose, glucose, Ca, Na values were higher in the ripe stage...
January 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/28870197/polarity-based-characterization-of-biologically-active-extracts-of-ajuga-bracteosa-wall-ex-benth-and-rp-hplc-analysis
#12
Syeda Saniya Zahra, Madiha Ahmed, Muhammad Qasim, Bilquees Gul, Muhammad Zia, Bushra Mirza, Ihsan-Ul Haq
BACKGROUND: The concept of botanical therapeutics has revitalized due to wide importance of plant derived pharmaceuticals. Therefore, the ameliorative characteristics of Ajuga bracteosa were studied. METHODS: Total phenolic content, flavonoid content, antioxidant capacity, reducing power and free-radical scavenging activity were determined colorimetrically. Specific polyphenols were quantified by RP-HPLC analysis. Preliminary cytotoxicity was tested using brine shrimp lethality assay while antiproliferative activity against THP-1 and Hep-G2 cell lines was determined by MTT and SRB protocols respectively...
September 5, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28867094/antioxidant-properties-of-selected-fruit-cultivars-grown-in-sri-lanka
#13
K D R R Silva, M S F Sirasa
Extracts of twenty locally available Sri Lankan fruits were analysed for 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity, ferrous reducing antioxidant power (FRAP), total phenolic content (TPC), total flavonoid content (TFC) and vitamin C content. The results showed that gooseberry (Phyllanthus emblica 'local') exhibited the highest DPPH scavenging activity (111.25mg ascorbic acid equivalent antioxidant capacity (AEAC)/g), FRAP (1022.05μmol FeSO4/g), TPC (915.7mg gallic acid equivalents (GAE)/100g), TFC (873...
January 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/28861213/idiopathic-non-histaminergic-acquired-angioedema-a-case-series-and-discussion-of-published-clinical-trials
#14
Martin Christian Bucher, Tatjana Petkovic, Arthur Helbling, Urs Christian Steiner
BACKGROUND: Idiopathic non-histaminergic acquired angioedema (InH-AAE) is a rare disease for which there are no available laboratory parameters to clearly define the disorder. Therapy is often difficult and various treatment options have been proposed. In this paper, we have evaluated the most effective therapies for InH-AAE on the basis of current literature and report the therapeutic effect of omalizumab in three patients with InH-AAE. METHODS: Literature was searched with a combination of MeSH/EMTREE terms and freetext search for angioedema and therapy/omalizumab in the databases Medline (Ovid), PubMed/Premedline, Embase, Cochrane library and Scopus with no time or language restrictions...
2017: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/28855038/-effect-of-scanning-and-reconstruction-parameters-on-three-dimensional-volume-and-ct-value-measurement-of-pulmonary-nodules-a-phantom-study
#15
Datong Su, Lei Feng, Yingjian Jiang, Ying Wang
BACKGROUND: The computed tomography (CT) follow-up of indeterminate pulmonary nodules aiming to evaluate the change of the volume and CT value is the common strategy in clinic. The CT dose needs to considered on serious CT scans in addition to the measurement accuracy. The purpose of this study is to quantify the precision of pulmonary nodule volumetric measurement and CT value measurement with various tube currents and reconstruction algorithms in a phantom study with dual-energy CT...
August 20, 2017: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
https://www.readbyqxmd.com/read/28844305/regenerative-endodontics-for-adult-patients
#16
Ling He, Sahng G Kim, Qimei Gong, Juan Zhong, Sainan Wang, Xuedong Zhou, Ling Ye, Junqi Ling, Jeremy J Mao
The goal of endodontics is to save teeth. Since inception, endodontic treatments are performed to obturate disinfected root canals with inert materials such as gutta-percha. Although teeth can be saved after successful endodontic treatments, they are devitalized and therefore susceptible to reinfections and fractures. The American Association of Endodontists (AAE) has made a tremendous effort to revitalize disinfected immature permanent teeth in children and adolescents with diagnoses including pulp necrosis or apical periodontitis...
September 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28844223/aae-position-statement-aae-guidance-on-the-use-of-systemic-antibiotics-in-endodontics
#17
EDITORIAL
(no author information available yet)
No abstract text is available yet for this article.
September 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28827984/ramalina-capitata-ach-nyl-acetone-extract-hplc-analysis-genotoxicity-cholinesterase-antioxidant-and-antibacterial-activity
#18
Ivana Zrnzevic, Miroslava Stankovic, Vesna Stankov Jovanovic, Violeta Mitic, Aleksandra Dordevic, Ivana Zlatanovic, Gordana Stojanovic
In the present investigation, effects of Ramalina capitata acetone extract on micronucleus distribution on human lymphocytes, on cholinesterase activity and antioxidant activity (by the CUPRAC method) were examined, for the first time as well as its HPLC profile. Additionally, total phenolic compounds (TPC), antioxidant properties (estimated via DPPH, ABTS and TRP assays) and antibacterial activity were determined. The predominant phenolic compounds in this extract were evernic, everninic and obtusatic acids...
2017: EXCLI journal
https://www.readbyqxmd.com/read/28774308/polarity-directed-optimization-of-phytochemical-and-in-vitro-biological-potential-of-an-indigenous-folklore-quercus-dilatata-lindl-ex-royle
#19
Madiha Ahmed, Humaira Fatima, Muhammad Qasim, Bilquees Gul, Ihsan-Ul-Haq
BACKGROUND: Plants have served either as a natural templates for the development of new chemicals or a phytomedicine since antiquity. Therefore, the present study was aimed to appraise the polarity directed antioxidant, cytotoxic, protein kinase inhibitory, antileishmanial and glucose modulatory attributes of a Himalayan medicinal plant- Quercus dilatata. METHODS: Total phenolic and flavonoid contents were determined colorimetrically and various polyphenols were identified by RP-HPLC analysis...
August 3, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28770462/predictive-value-of-18-f-fdg-pet-ct-in-patients-with-acute-type-b-aortic-intramural-hematoma
#20
Fan Yang, Jianfang Luo, Qingyi Hou, Nianjin Xie, Zhiqiang Nie, Wenhui Huang, Yuan Liu, Yingling Zhou, Jiyan Chen, Qingshan Geng
BACKGROUND: The clinical course and predictors of adverse aortic events (AAE) in patients with acute Stanford type B intramural hematoma (IMH) remain controversial. This study aimed to investigate whether (18)F-FDG PET/CT can predict risk in patients with acute type B IMH. METHODS AND RESULTS: This study included 34 patients with acute type B IMH who underwent PET/CT within 14 days from the onset of symptoms. The maximal standardized uptake values (SUVmax) of (18)F-FDG uptake was significantly different between patients with or without AAE (4...
August 2, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
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