keyword
https://read.qxmd.com/read/38521154/eight-years-and-beyond-longitudinal-changes-of-peripapillary-structures-on-oct-in-adult-myopia
#1
JOURNAL ARTICLE
Yi Dai Md PhD, Li Wang Md PhD, Jie Hong Ms, Xinghuai Sun Md PhD
PURPOSE: To investigate the long-term changes of peripapillary structures detected by enhanced depth imaging of OCT in adult myopia. DESIGN: Observational case series. METHODS: Myopic participants who had undergone a full baseline ophthalmologic examination and followed up with a minimum of 8 years were included. Using enhanced depth imaging of OCT, scans around the optic disc in the follow-up mode which enabled capturing of the same positions were performed in 65 eyes...
March 21, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38517389/viral-anterior-uveitis-differences-in-retinal-vessel-area-density-between-the-affected-and-non-affected-eye-using-optical-coherence-tomography-angiography
#2
JOURNAL ARTICLE
Anna-Karina B Maier, Daniel Mandrossa, Emanuel Reitemeyer, Sibylle Winterhalter, Anne Rübsam, Uwe Pleyer
PURPOSE: To investigate differences in the retinal vessel area density (VAD) on optical coherence tomography angiography (OCTA) between eyes with unilateral herpetic viral anterior uveitis (VAU) (herpes-simplex virus (HSV) and varicella-zoster virus (VZV)) and the non-affected fellow eye. METHODS: In this monocentric, observational, prospective case series we analyzed the VAD of the macula, optic disc, and peripapillary region in affected and non-affected eyes of 22 patients with HSV-positive and 22 patients with VZV-positive VAU using OCTA...
March 22, 2024: Ocular Immunology and Inflammation
https://read.qxmd.com/read/38480784/morphological-differences-of-the-neuroretinal-rim-between-temporally-tilted-and-non-tilted-optic-discs-in-healthy-eyes
#3
JOURNAL ARTICLE
Chan Woong Joo, Youn Joo Choi, Han Ul Kim, Sung Pyo Park, Kyeong Ik Na
This study aimed to compare morphological differences of the neuroretinal rim between the temporally tilted and non-tilted optic discs in healthy eyes. We prospectively enrolled participants aged 20-40 years with temporally tilted or non-tilted optic discs. The optic nerve head parameters were analyzed using spectral domain-optical coherence tomography. The angle between the Bruch's membrane opening (BMO) plane and BMO-minimum rim width (BMO-MRW) was termed "BMO-MRW angle". Peripapillary retinal nerve fiber layer thickness (pRNFLT) and BMO-based parameters were compared between the temporally tilted and non-tilted disc groups...
March 13, 2024: Scientific Reports
https://read.qxmd.com/read/38240777/accuracy-of-bruch-s-membrane-opening-minimum-rim-width-and-retinal-nerve-fiber-layer-thickness-in-glaucoma-diagnosis-depending-on-optic-disc-size
#4
JOURNAL ARTICLE
Verena Anna Englmaier, Jens Julian Storp, Martin Dominik Leclaire, Larissa Lahme, Viktoria Constanze Brücher, Julia Biermann, Raphael Diener, Nicole Eter
BACKGROUND/AIM: The aim of this paper is to compare retinal nerve fiber layer thickness (RNFL) and Bruch's membrane opening-based minimum rim width (BMO-MRW) in terms of their performance in detecting early and moderate/advanced glaucoma using receiver operating characteristics (ROC) analysis and the classification using the 5th percentile as a cut-off. METHODS: One hundred eyes from 100 patients with early glaucoma (mean deviation (MD): < -5.0 dB) and 100 eyes from 100 patients with moderate/advanced glaucoma (MD: > -5...
January 19, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38104770/optical-coherence-tomography-segmentation-errors-with-basement-membrane-opening-minimum-rim-width-as-compared-to-retinal-nerve-fiber-layer-thickness
#5
JOURNAL ARTICLE
Hongli Yang, Jack P Rees, Facundo G Sanchez, Stuart K Gardiner, Steven L Mansberger
OBJECTIVE: To compare the magnitude and location of automated segmentation errors of the Bruch's membrane opening-minimum rim width (BMO-MRW) and retinal nerve fiber layer thickness (RNFLT). DESIGN: Cross-sectional study PARTICIPANTS: We included 162 glaucoma suspect or open-angle glaucoma eyes from 162 participants. METHODS: We used a spectral-domain optic coherence tomography (Spectralis 870 nm, Heidelberg Engineering, Heidelberg, Germany) to image the optic nerve with 24 radial optic nerve head B-scans and a 12-degree peripapillary circle scan, and exported the native 'automated segmentation only' results for BMO-MRW and RNFLT...
December 15, 2023: Ophthalmology Glaucoma
https://read.qxmd.com/read/37939715/assessment-of-optic-disc-morphological-characteristics-and-related-factors-of-highly-myopic-eyes-in-chinese-school-aged-children
#6
JOURNAL ARTICLE
Hui Wang, Song-Guo Li, Shu-Dong Jing
CLINICAL RELEVANCE: The morphological characteristics of the optic nerve head (ONH) in myopic eyes are a clinically significant issue, especially for high myopia in school-aged children, and this can be monitored using optical coherence tomography. BACKGROUND: The purpose of this study is to investigate the morphological characteristics of ONH, and the factors associated with peripapillary choroidal thickness in Chinese school-aged high myopia children. METHODS: A total of 48 patients, possessing 48 high myopia eyes and 48 contralateral low myopia eyes were enrolled...
November 8, 2023: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://read.qxmd.com/read/37868142/clinical-findings-and-optical-coherence-tomography-measurements-of-pediatric-patients-with-papilledema-and-pseudopapilledema
#7
JOURNAL ARTICLE
Ayşin Tuba Kaplan, Sibel Öskan Yalçın, Safiye Güneş Sağer
OBJECTIVES: To compare the clinical findings and multimodal imaging of pediatric patients diagnosed with papilledema and pseudopapilledema with those of healthy individuals. MATERIALS AND METHODS: Ninety children (<18 years of age) referred for suspected papilledema were included in this study. All patients underwent optical coherence tomography (OCT) imaging and were compared with normal control subjects. RESULTS: Fifty-eight children diagnosed with pseudopapilledema, 32 children with mild-to-moderate papilledema, and 40 controls were evaluated...
October 19, 2023: Turkish Journal of Ophthalmology
https://read.qxmd.com/read/37796490/deep-optic-nerve-head-morphology-in-tilted-disc-syndrome-and-its-clinical-implication-on-visual-damage
#8
JOURNAL ARTICLE
Eun Jung Lee, Jong Chul Han, Changwon Kee
PURPOSE: To study deep optic nerve head (ONH) morphology in tilted disc syndrome (TDS) and identify factors associated with retinal nerve fiber layer (RNFL) defect. METHODS: In patients with TDS, we evaluated the optic disc shape using the Bruch's membrane opening (BMO)-anterior scleral canal opening (ASCO) offset and measured the border tissue (BT) length, depth, and angle in the direction of the tilt, using radial ONH optical coherence tomography (OCT). We compared the parameters between the TDS groups with and without RNFL defects...
October 3, 2023: Investigative Ophthalmology & Visual Science
https://read.qxmd.com/read/37543611/performance-of-neuroretinal-rim-thickness-measurement-by-cirrus-high-definition-optical-coherence-tomography-in-myopic-eyes
#9
JOURNAL ARTICLE
Andrew K C Lam, H C Lai, Y K Sung, W H Lam, C M Tiu
Neuroretinal rim (NRR) measurement can aid the diagnosis of glaucoma. A few studies reported that Cirrus optical coherence tomography (OCT) had NRR segmentation errors. The current study investigated segmentation success of NRR in myopic eyes using the Cirrus built-in software and to determine the number of acquisitions required to identify NRR thinning. Right eye of 87 healthy adult myopes had an optic disc scanned using Cirrus HD-OCT for five successive acquisitions. A masked examiner evaluated 36 radial line images of each scan to screen for segmentation errors using the built-in software at the Bruch's membrane opening (BMO) and/or internal limiting membrane (ILM)...
August 5, 2023: Scientific Reports
https://read.qxmd.com/read/37530273/comparison-of-glaucomatous-from-non-glaucomatous-optic-neuropathy-using-bruch-s-membrane-opening-minimum-rim-width-optical-coherence-tomography-measurements
#10
JOURNAL ARTICLE
Hirika Gosalia, Karthik M Kumar, A K Karan, Veerappan R Saravanan, Virna M Shah
PURPOSE: To compare glaucomatous from non-glaucomatous optic atrophy using optical coherence tomography (OCT) based on the measurement values of Bruch's membrane opening minimum rim width (BMO-MRW), which is a difficult task otherwise due to their varied course of disease progression, treatment protocols, and systemic association to visual impairment. METHODS: This study was conducted in 40 eyes, comprising 20 eyes with non-glaucomatous optic neuropathy (NGON) and 20 eyes with glaucomatous optic neuropathy (GON)...
August 2023: Indian Journal of Ophthalmology
https://read.qxmd.com/read/37523634/optical-coherence-tomography-derived-measurements-of-the-optic-nerve-head-structure-of-aboriginal-and-torres-strait-islander-children
#11
JOURNAL ARTICLE
Rebecca A Cox, Scott A Read, Shelley Hopkins, David Alonso-Caneiro, Joanne M Wood
PURPOSE: To examine the optic nerve head (ONH) characteristics of visually normal Aboriginal and Torres Strait Islander children and non-Indigenous Australian children. PRCIS: This study demonstrated significant differences in optic nerve head characteristics in Aboriginal and Torres Strait Islander compared to non-Indigenous children which has implications for glaucoma risk and diagnosis in Aboriginal and Torres Strait Islander populations. PATIENTS AND METHODS: Spectral domain optical coherence tomography (OCT) imaging was performed on the right eye of 95 Aboriginal and Torres Strait Islander children and 149 non-Indigenous Australian children (5-18 years)...
July 25, 2023: Journal of Glaucoma
https://read.qxmd.com/read/37517426/impact-of-obesity-on-peripapillary-choroidal-thickness-macular-choroidal-thickness-and-lamina-cribrosa-morphology
#12
JOURNAL ARTICLE
Dr Sumeyra Koprubasi, Assist Prof Dr Erkan Bulut
BACKGROUND: Obesity is known to be a significant risk factor for many ocular diseases. In order to understand the mechanism of obesity-related ocular diseases, we examined the lamina cribrosa morphology, peripapillary choroidal thickness (PPCT), and macular choroidal thickness (MCT) in obese women using optical coherence tomography (OCT). METHODS: This comparative cross-sectional study included the right eyes of 72 obese women and 63 healthy women classified based on body mass index (BMI)...
July 28, 2023: Photodiagnosis and Photodynamic Therapy
https://read.qxmd.com/read/37146494/accurate-c-d-ratio-estimation-with-elliptical-fitting-for-oct-image-based-on-joint-segmentation-and-detection-network
#13
JOURNAL ARTICLE
Chenan Xu, Zhongyue Chen, Xiao Zhang, Yuanyuan Peng, Zhiwei Tan, Yu Fan, Xulong Liao, Haoyu Chen, Jiayan Shen, Xinjian Chen
Proper estimation of the cup-to-disc ratio (C/D ratio) plays a significant role in ophthalmic examinations, and it is urgent to improve the efficiency of C/D ratio automatic measurement. Therefore, we propose a new method for measuring the C/D ratio of OCTs in normal subjects. Firstly, the end-to-end deep convolution network is used to segment and detect the inner limiting membrane (ILM) and the two Bruch's membrane opening (BMO) terminations. Then, we introduce an ellipse fitting technique to post-process the edge of the optic disc...
April 20, 2023: Computers in Biology and Medicine
https://read.qxmd.com/read/37048556/evaluation-of-retinal-nerve-fiber-layer-and-macular-ganglion-cell-layer-thickness-in-relation-to-optic-disc-size
#14
JOURNAL ARTICLE
Jens Julian Storp, Nils Hendrik Storp, Moritz Fabian Danzer, Nicole Eter, Julia Biermann
To investigate whether optic nerve ganglion cell amount is dependent on optic disc size, this trial analyzes the correlation between Bruch's membrane opening area (BMOA) and retinal nerve fiber layer (RNFL) thickness as well as macular ganglion cell layer thickness (mGCLT). Additionally, differences in RNFL and mGCLT regarding various optic disc cohorts are evaluated. This retrospective, monocentric study included 501 healthy eyes of 287 patients from the University Hospital Münster, Germany, who received macular and optic disc optical coherence tomography (OCT) scans...
March 24, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/37022704/prevalence-and-characteristics-of-peripapillary-gamma-zone-in-children-with-different-refractive-status-the-hong-kong-children-eye-study
#15
JOURNAL ARTICLE
Xiu Juan Zhang, Duncan Ka Shun Chau, Yu Meng Wang, Cynthia Sze Hang Cheung, Hei-Nga Chan, Jian Shi, Ka Ming Nip, Shumin Tang, Ryan C F Chan, Alistair Lau, Sit Hui Kei, Ka Wai Kam, Alvin L Young, Li Jia Chen, Clement C Tham, Kyoko Ohno-Matsui, Chi Pui Pang, Jason C Yam
PURPOSE: This study aimed to assess the prevalence and characteristics of the peripapillary gamma zone in myopic, emmetropic, and hyperopic eyes of Chinese children. METHODS: Overall, 1274 children aged 6 to 8 years from the Hong Kong Children Eye Study underwent ocular examinations, including measurements of cycloplegic auto-refraction and axial length (AL). The optic disc was imaged using a Spectralis optical coherence tomography (OCT) unit and a protocol involving 24 equally spaced radial B-scans...
April 3, 2023: Investigative Ophthalmology & Visual Science
https://read.qxmd.com/read/36988950/ocular-deformations-in-spaceflight-associated-neuro-ocular-syndrome-and-idiopathic-intracranial-hypertension
#16
JOURNAL ARTICLE
Patrick A Sibony, Steven S Laurie, Connor R Ferguson, Laura P Pardon, Millennia Young, F James Rohlf, Brandon R Macias
PURPOSE: Spaceflight-associated neuro-ocular syndrome (SANS) shares several clinical features with idiopathic intracranial-hypertension (IIH), namely disc edema, globe-flattening, hyperopia, and choroidal folds. Globe-flattening is caused by increased intracranial pressure (ICP) in IIH, but the cause in SANS is uncertain. If increased ICP alone causes SANS, then the ocular deformations should be similar to IIH; if not, alternative mechanisms would be implicated. METHODS: Using optical coherence tomography (OCT) axial images of the optic nerve head, we compared "pre to post" ocular deformations in 22 patients with IIH to 25 crewmembers with SANS...
March 1, 2023: Investigative Ophthalmology & Visual Science
https://read.qxmd.com/read/36507529/deep-learning-classification-of-early-normal-tension-glaucoma-and-glaucoma-suspect-eyes-using-bruch-s-membrane-opening-based-disc-photography
#17
JOURNAL ARTICLE
Sat Byul Seo, Hyun-Kyung Cho
PURPOSE: We aimed to investigate the performance of a deep learning model to discriminate early normal-tension glaucoma (NTG) from glaucoma suspect (GS) eyes using Bruch's membrane opening (BMO)-based optic disc photography. METHODS: 501 subjects in total were included in this cross-sectional study, including 255 GS eyes and 246 eyes of early NTG patients. BMO-based optic disc photography (BMO overview) was obtained from spectral-domain optical coherence tomography (OCT)...
2022: Frontiers in Medicine
https://read.qxmd.com/read/36404967/diagnostic-evaluation-of-optical-coherence-tomography-parameters-in-normal-preperimetric-and-perimetric-glaucoma-patients
#18
JOURNAL ARTICLE
Aimy Mastura Zurairah Yusof, Othmaliza Othman, Seng Fai Tang, Mohd Rohaizat Hassan, Norshamsiah Md Din
AIM: To compare the diagnostic ability of glaucoma parameters measured by the optical coherence tomography (OCT) in normal, preperimetric glaucoma (PPG) and perimetric glaucoma (PG) patients. METHODS: This cross-sectional observational study includes 127 eyes of 127 subjects. Patients were divided into PPG (51 eyes), PG (46 eyes), and normal controls (30 eyes) based on clinical optic disc assessment and Humphrey visual field changes. The Heidelberg Spectralis OCT machine using Glaucoma Module Premium Edition software was used to measure the retinal nerve fiber layer (RNFL) and Bruch's membrane opening-minimum rim width (BMO-MRW) to assess the optic nerve head and ganglion cell layer (GCL) thickness in the macula...
2022: International Journal of Ophthalmology
https://read.qxmd.com/read/36292204/comparison-of-spectral-domain-oct-versus-swept-source-oct-for-the-detection-of-deep-optic-disc-drusen
#19
JOURNAL ARTICLE
Simon P Rothenbuehler, Lasse Malmqvist, Mohamed Belmouhand, Jakob Bjerager, Peter M Maloca, Michael Larsen, Steffen Hamann
Deep optic disc drusen (ODD) are located below Bruch's membrane opening (BMO) and may go undetected due to the challenges in imaging them. The purpose of this study is a head-to-head comparison of currently widely used imaging technologies: swept-source optical coherence tomography (SS-OCT; DRI OCT-1 Triton, Topcon) and enhanced depth imaging spectral-domain optical coherence tomography (EDI SD-OCT; Spectralis OCT, Heidelberg Engineering) for the detection of deep ODD and associated imaging features. The eyes included in this study had undergone high-resolution imaging via both EDI SD-OCT and SS-OCT volume scans, which showed at least one deep ODD or a hyperreflective line (HL)...
October 17, 2022: Diagnostics
https://read.qxmd.com/read/36246173/volumetric-measurement-of-peripapillary-hyperreflective-ovoid-masslike-structures-in-patients-with-optic-disc-drusen
#20
JOURNAL ARTICLE
Morten Jørgensen, Lasse Malmqvist, Alexander E Hansen, J Alexander Fraser, Steffen Hamann
Purpose: To develop a method to determine the volume of peripapillary hyperreflective ovoid masslike structures (PHOMS) and to examine the correlation between PHOMS and anatomic optic nerve head characteristics in a large cohort of patients with optic disc drusen (ODD). Design: Retrospective, observational study of patients with ODD. Participants: Patients with ODD seen in a 3-year period. Methods: We determined the prevalence of PHOMS...
March 2022: Ophthalmol Sci
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