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https://www.readbyqxmd.com/read/28760034/complete-anatomic-reduction-and-monosegmental-fusion-for-lumbar-spondylolisthesis-of-grade-ii-and-higher-use-of-the-minimally-invasive-rocking-technique
#1
Deshpande V Rajakumar, Akshay Hari, Murali Krishna, Ankit Sharma, Manjunatha Reddy
OBJECTIVE Different surgical approaches have been described for treatment of spondylolisthesis, including in situ fusions, reductions of various degrees, and inclusion of healthy adjacent segments into the fusion construct. To the authors' knowledge, there are only sparse reports describing consistent complete reduction and monosegmental transforaminal lumbar interbody fusion for spondylolisthesis using a minimally invasive technique. The authors assess the efficacy of this technique in the reduction of local deformity and correction of overall sagittal profile in single-level spondylolisthesis...
August 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28760032/minimally-invasive-transforaminal-lumbar-interbody-fusion-with-expandable-versus-static-interbody-devices-radiographic-assessment-of-sagittal-segmental-and-pelvic-parameters
#2
Ammar H Hawasli, Jawad M Khalifeh, Ajay Chatrath, Chester K Yarbrough, Wilson Z Ray
OBJECTIVE Minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) has been adopted as an alternative technique to hasten recovery and minimize postoperative morbidity. Advances in instrumentation technologies and operative techniques have evolved to maximize patient outcomes as well as radiographic results. The development of expandable interbody devices allows a surgeon to perform MIS-TLIF with minimal tissue disruption. However, sagittal segmental and pelvic radiographic outcomes after MIS-TLIF with expandable interbody devices are not well characterized...
August 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28750894/patient-acceptability-of-3d-printed-medicines
#3
Alvaro Goyanes, Mariagiovanna Scarpa, Michael Kamlow, Simon Gaisford, Abdul W Basit, Mine Orlu
Patient-centric medicine is a derivative term for personalised medicine, whereby the pharmaceutical product provides the best overall benefit by meeting the comprehensive needs of the individual; considering the end-user from the beginning of the formulation design process right through development to an end product is a must. One way in which to obtain personalised medicines, on-site and on-demand is by three-dimensional printing (3DP). The aim of this study was to investigate the influence of the shape, size and colour of different placebo 3D printed tablets (Printlets™) manufactured by fused deposition modelling (FDM) 3DP on end-user acceptability regarding picking and swallowing...
July 24, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28742160/sub-classification-of-myopic-glaucomatous-eyes-according-to-optic-disc-and-peripapillary-features
#4
Seungbong Han, Kyung Rim Sung, Jimin Park, Joo Young Yoon, Joong Won Shin
PURPOSE: To investigate the sub-classification of myopic glaucomatous eyes by optic disc and peripapillary features. METHODS: Optic disc tilt and torsion were determined from retinal nerve fiber layer photographs. Based on the location of the Bruch's membrane (BM) opening within the β-zone of the peripapillary atrophy (PPA) area, the widths of β-zone PPA (PPA1W), PPA+BM (PPA2W), and PPA-BM (PPA3W) were measured with enhanced depth imaging spectral-domain optical coherence tomography...
2017: PloS One
https://www.readbyqxmd.com/read/28731059/optical-coherence-tomography-detection-of-characteristic-retinal-nerve-fiber-layer-thinning-in-nasal-hypoplasia-of-the-optic-disc
#5
M Haruta, R Kodama, R Yamakawa
PurposeTo determine the clinical usefulness of optical coherence tomography (OCT) for detecting thinning of the retinal nerve fiber layer (RNFL) in eyes with nasal hypoplasia of the optic discs (NHOD).Patients and methodsThe medical records of five patients (eight eyes) with NHOD were reviewed. The ratio of the disc-macula distance to the disc diameter (DM/DD) and the disc ovality ratio of the minimal to maximal DD were assessed using fundus photographs. The RNFL thicknesses of the temporal, superior, nasal, and inferior quadrants were evaluated using OCT quadrant maps...
July 21, 2017: Eye
https://www.readbyqxmd.com/read/28729947/associations-between-optic-nerve-head-related-anatomical-parameters-and-refractive-error-over-the-full-range-of-glaucoma-severity
#6
Neda Baniasadi, Mengyu Wang, Hui Wang, Mufeed Mahd, Tobias Elze
PURPOSE: To evaluate the associations between optic disc (OD)-related anatomical parameters (interartery angle [IAA] between superior and inferior temporal retinal arteries, OD tilt [TL], rotation [ROT], and torsion [TO], OD surface curvature [CUR], and central retinal vessel trunk entry point location [CRVTL] on OD) and the spherical equivalent of refractive error (SE), and to assess the impact of glaucoma severity on these relationships. METHODS: Cirrus optical coherence tomography (OCT) fundus images and 24-2 visual fields of 438 patients were included...
July 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/28725046/the-location-of-the-deepest-point-of-the-eyeball-determines-the-optic-disc-configuration
#7
Yong Chan Kim, Younhea Jung, Hae-Young Lopilly Park, Chan Kee Park
Tilted and rotated appearances are hallmarks of the myopic optic disc. As the eyeball grows axially, the posterior pole elongates not only globally but in a localized manner as well. In this process, the optic disc is pulled towards the deepest point of the elongated eyeball, which might result in a change in optic disc configuration. Thus, we hypothesized that analyzing the variation of posterior pole contour can play a major role in understanding optic disc configuration in myopic subjects. By analyzing consecutive images of swept source OCT coronal sections at the posterior pole, the deepest interface between Bruch's membrane and the choroid could be identified as the deepest point of the eyeball (DPE)...
July 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28689392/preservation-of-motion-at-the-surgical-level-after-minimally-invasive-posterior-cervical-foraminotomy
#8
Young-Seok Lee, Young-Baeg Kim, Seung-Won Park, Dong-Ho Kang
OBJECTIVE: Although minimally invasive posterior cervical foraminotomy (MI-PCF) is an established approach for motion preservation, the outcomes are variable among patients. The objective of this study was to identify significant factors that influence motion preservation after MI-PCF. METHODS: Forty-eight patients who had undergone MI-PCF between 2004 and 2012 on a total of 70 levels were studied. Cervical parameters measured using plain radiography included C2-7 plumb line, C2-7 Cobb angle, T1 slope, thoracic outlet angle, neck tilt, and disc height before and 24 months after surgery...
July 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/28654981/optic-nerve-tilt-crescent-ovality-and-torsion-in-a-multi-ethnic-cohort-of-young-adults-with-and-without-myopia
#9
Wendy L Marsh-Tootle, Elise Harb, Wei Hou, Qinghua Zhang, Heather A Anderson, Katherine Weise, Thomas T Norton, Jane Gwiazda, Leslie Hyman
Purpose: The purpose of this article is to evaluate optic nerve head (ONH) characteristics in an ethnically diverse cohort of young U.S. adults. Methods: In this study, 409 myopes and 206 nonmyopes (median age 22 years) completed measures including biometry and spectral domain optical coherence tomography from enface (ovality and torsion) and cross-sectional (tilt and crescent width) scans. Associated factors were evaluated using multivariable models. Results: In myopic versus nonmyopic right eyes, median tilt (6...
June 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28646704/location-and-characterization-of-lignin-in-tracheid-cell-walls-of-radiata-pine-pinus-radiata-d-don-compression-woods
#10
Miao Zhang, Catherine Lapierre, Noor Liyana Nouxman, Michel K Nieuwoudt, Bronwen G Smith, Ramesh R Chavan, Brian H McArdle, Philip J Harris
Tilted stems of softwoods form compression wood (CW) and opposite wood (OW) on their lower and upper sides, respectively. More is known about the most severe form of CW, severe CW (SCW), but mild CWs (MCWs) also occur widely. Two grades of MCWs, MCW1 and MCW2, as well as SCW and OW were identified in the stems of radiata pine (Pinus radiata) that had been slightly tilted. The four wood types were identified by the distribution of lignin in the tracheid walls determined by fluorescence microscopy. A solution of the fluorescent dye acridine orange (AO) (0...
June 15, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28641680/ophthalmological-evaluation-of-integrated-resistance-and-aerobic-training-during-70-day-bed-rest
#11
Giovanni Taibbi, Ronita L Cromwell, Susana B Zanello, Patrice O Yarbough, Robert J Ploutz-Snyder, Bernard F Godley, Gianmarco Vizzeri
INTRODUCTION: We evaluated ophthalmic changes in healthy individuals who underwent integrated resistance and aerobic training (iRAT) during 70-d 6° head-down tilt (HDT) bed rest (BR). METHODS: Participants were selected using NASA standard screening procedures. Standardized NASA BR conditions were implemented. Subjects were randomly assigned to the iRAT protocol or no exercise during HDTBR. Weekly ophthalmic examinations were performed in the sitting (pre/post-BR only) and HDT (BR only) positions...
July 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28611153/effects-of-short-term-mild-hypercapnia-during-head-down-tilt-on-intracranial-pressure-and-ocular-structures-in-healthy-human-subjects
#12
Steven S Laurie, Gianmarco Vizzeri, Giovanni Taibbi, Connor R Ferguson, Xiao Hu, Stuart M C Lee, Robert Ploutz-Snyder, Scott M Smith, Sara R Zwart, Michael B Stenger
Many astronauts experience ocular structural and functional changes during long-duration spaceflight, including choroidal folds, optic disc edema, globe flattening, optic nerve sheath diameter (ONSD) distension, retinal nerve fiber layer thickening, and decreased visual acuity. The leading hypothesis suggests that weightlessness-induced cephalad fluid shifts increase intracranial pressure (ICP), which contributes to the ocular structural changes, but elevated ambient CO2 levels on the International Space Station may also be a factor...
June 2017: Physiological Reports
https://www.readbyqxmd.com/read/28555457/-situs-inversus-of-the-optic-nerve-a-case-report
#13
I Lopez-Cuenca, R de Hoz, E Salobrar-Garcia, B Rojas, A I Ramirez, J J Salazar, A Trivino, J M Ramirez
INTRODUCTION: Situs inversus of the optic nerve is a congenital anomaly characterised by the emergence of the vessels in the retina towards the nose rather than in a temporal direction. It is caused by an anomalous insertion of the optic stalks into the optic vesicle that gives rise to dysversion of the head of the optic nerve. It is not an isolated condition and usually appears jointly with tilted disc syndrome and in patients with myopia. It is characterised by the presence of inferior conus atrophy, deficiencies in the temporal visual field, refraction defects and ambliopy...
June 1, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28551164/multiple-temporal-lamina-cribrosa-defects-in-myopic-eyes-with-glaucoma-and-their-association-with-visual-field-defects
#14
Yu Sawada, Makoto Araie, Makoto Ishikawa, Takeshi Yoshitomi
PURPOSE: To investigate characteristics of lamina cribrosa (LC) defects in myopic eyes with open-angle glaucoma (OAG) using spectral-domain (SD) optical coherence tomography (OCT). DESIGN: Cross-sectional study. PARTICIPANTS: One hundred thirty-three eyes with OAG and 83 eyes without OAG, with axial length of 24 mm or more. METHODS: Serial enhanced depth imaging SD OCT B-scans of the optic disc were acquired and reviewed for LC defects (diameter, ≥100 μm) and large pores (diameter, 60-100 μm)...
May 24, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28545560/influences-of-lumbar-disc-herniation-on-the-kinematics-in-multi-segmental-spine-pelvis-and-lower-extremities-during-five-activities-of-daily-living
#15
Shengzheng Kuai, Wenyu Zhou, Zhenhua Liao, Run Ji, Daiqi Guo, Rui Zhang, Weiqiang Liu
BACKGROUND: Low back pain (LBP) is a common problem that can contribute to motor dysfunction. Previous studies reporting the changes in kinematic characteristics caused by LBP present conflicting results. This study aimed to apply the multisegmental spinal model to investigate the kinematic changes in patients with lumbar disc herniation (LDH) during five activities of daily living (ADLs). METHODS: Twenty-six healthy subjects and 7 LDH patients participated in this study and performed level walking, stair climbing, trunk flexion, and ipsilateral and contralateral pickups...
May 25, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28542289/structural-parameters-associated-with-location-of-peaks-of-peripapillary-retinal-nerve-fiber-layer-thickness-in-young-healthy-eyes
#16
Takehiro Yamashita, Ryo Asaoka, Yuya Kii, Hiroto Terasaki, Hiroshi Murata, Taiji Sakamoto
The location of the peaks of the circumpapillary retinal nerve fiber layer (cpRNFL) thickness is affected by several ocular parameters. In this study, we have generated equations that can determine the peaks of the cpRNFL. This study was a prospective, observational, cross sectional study of 118 healthy right eyes. The axial length, optic disc tilt, superiortemporal (ST)- and inferiortemporal (IT)-peaks of the cpRNFL thickness, and angles of the ST and IT retinal arteries (RA) and veins (RV) were determined...
2017: PloS One
https://www.readbyqxmd.com/read/28511802/-a-continuous-series-of-27-adult-patients-treated-for-l5-s1-isthmic-spondylolisthesis-by-combined-approach-clinical-and-radiological-outcomes-at-1-year-follow-up
#17
N Koné, E Freitas Olim, P Coloma, A Rusconi, L Chenin, O Sy, I S Souaré, C Barrey
Through this single-center consecutive prospective study, we evaluated the results of a combined approach for L5-S1 isthmic spondylolisthesis, using a polyetheretherketone (PEEK) interbody lordotic cage during anterior approach and pedicle screw-based posterior fixation. Between 2010 and 2014, 27 adult patients were treated for L5-S1 isthmic spondylolisthesis (high and low grades) by a combined approach with a minimum follow-up of one year. Clinical outcome was assessed before surgical treatment and at four months and one year after surgery by: VAS, Oswestry Index (ODI) and Rolland-Morris scores...
May 13, 2017: Neuro-Chirurgie
https://www.readbyqxmd.com/read/28501956/an-in-vitro-evaluation-of-sagittal-alignment-in-the-cervical-spine-after-insertion-of-supraphysiologic-lordotic-implants
#18
Donald J Blaskiewicz, Jeffrey E Harris, Patrick P Han, Alexander W Turner, Gregory M Mundis
PURPOSE: Cervical spine malalignment can develop as a consequence of degenerative disc disease or following spinal surgery. When normal sagittal alignment of the spine is disrupted, further degeneration may occur adjacent to the deformity. The purpose of this study was to investigate changes in lordosis and sagittal alignment in the cervical spine after insertion of supraphysiologic lordotic implants. METHODS: Eight cadaveric cervical spines (Occiput-T1) were tested...
May 13, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28495841/lower-body-negative-pressure-decreases-noninvasively-measured-intracranial-pressure-and-internal-jugular-vein-cross-sectional-area-during-head-down-tilt
#19
William Watkins, Alan R Hargens, Shannon Seidl, Erika Marie Clary, Brandon R Macias
Long-term spaceflight induces a near visual acuity change in ~50% of astronauts. In some crew members, postflight cerebrospinal fluid (CSF) opening pressures by lumbar puncture are as high as 20.9 mmHg; these members demonstrated optic disc edema. CSF communicates through the cochlear aqueduct to affect perilymphatic pressure and tympanic membrane motion. We hypothesized that 50 mmHg of lower-body negative pressure (LBNP) during 15° head-down tilt (HDT) would mitigate elevations in internal jugular vein cross-sectional area (IJV CSA) and intracranial pressure (ICP)...
July 1, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28486730/die-randunscharfe-papille-eine-diagnostische-herausforderung
#20
Julia Biermann, Wolf Alexander Lagrèze
Correct differential diagnosis in cases of blurred optic disc margins is a challenging task for ophthalmologists. The reliable differentiation of pseudopapilloedema and true papilloedema has significant implications for proper patient management. Conditions that give rise to pseudopapilloedema include small crowded discs, tilted discs and optic nerve head drusen. Conditions that cause bilateral true swelling of the optic nerve head with initially good visual acuity include those that are secondary to raised intracranial pressure (optic disc edema, ODE)...
June 2017: Klinische Monatsblätter Für Augenheilkunde
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