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https://www.readbyqxmd.com/read/28732047/in-vivo-analysis-of-glaucoma-related-features-within-the-optic-nerve-head-using-enhanced-depth-imaging-optical-coherence-tomography
#1
Tiago S Prata, Flavio S Lopes, Vitor G Prado, Izabela Almeida, Igor Matsubara, Syril Dorairaj, Rafael L Furlanetto, Roberto M Vessani, Augusto Paranhos
Structural differences between optic nerve head (ONH) parameters in glaucomatous and non-glaucomatous eyes has been documented, however the association between such parameters in patients with different disease stages is yet to be elucidated. We investigated the relationship between different laminar and prelaminar ONH structures using enhanced depth imaging spectral-domain optical coherence tomography (EDI OCT) in a population with and without glaucoma. In this observational case-control study, we prospectively enrolled healthy individuals and glaucomatous patients with different disease stages...
2017: PloS One
https://www.readbyqxmd.com/read/28730092/parameters-of-ocular-fundus-on-spectral-domain-optical-coherence-tomography-for-glaucoma-diagnosis
#2
REVIEW
Yu-Lin Tao, Li-Ming Tao, Zheng-Xuan Jiang, He-Ting Liu, Kun Liang, Mo-Han Li, Xuan-Sheng Zhu, Yan-Lin Ren, Bing-Jie Cui
In this review, we summarize the progression of several parameters assessed by spectral-domain optical coherence tomography (SD-OCT) in recent years for the detection of glaucoma. Monitoring the progression of defects in the retinal nerve fiber layer (RNFL) thickness is essential. Imaging and analysis of retinal ganglion cells (RGCs) and inner plexiform layer (IPL), respectively, have been of great importance. Optic nerve head (ONH) topography obtained from 3D SD-OCT images is another crucial step. Other important assessments involve locating the Bruch's membrane opening (BMO), estimating the optic disc size and rim area, and measuring the lamina cribrosa displacement...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28700597/differentially-expressed-micrornas-in-diapausing-versus-hcl-treated-bombyx-embryos
#3
Wentao Fan, Yangsheng Zhong, Mingyue Qin, Bimin Lin, Fangyan Chen, Huichao Yan, Wenchu Li, Jianrong Lin
Differentially expressed microRNAs were detected to explore the molecular mechanisms of diapause termination. The total small RNA of diapause-destined silkworm eggs and HCl-treated eggs was extracted and then sequenced using HiSeq high-throughput method. 44 novel miRNAs were discovered. Compared to those in the diapause-destined eggs, 61 miRNAs showed significant changes in the acid-treated eggs, with 23 being up-regulated and 38 being down-regulated. The potential target genes of differentially expressed miRNAs were predicted by miRanda...
2017: PloS One
https://www.readbyqxmd.com/read/28672071/enzymatic-process-enhances-the-flavour-profile-and-increases-the-proportion-of-esters-in-citrus-essential-oils
#4
Kun Zhang, Ying Lin, Zhou-Jian Diao, Wei-Hua Zhang, Sui-Ping Zheng, Shu-Li Liang, Shuang-Yan Han
Citrus essential oils (CEOs) are important flavors in the food and confectionary industries. A lipase process was proposed for enhancing the flavor profiles and increasing the proportions of esters in CEOs. The effects of the enzymatic process were explored by detecting the constituents of the CEOs of American sweet orange oil (ASO) and Brazil mandarin oil (BMO) through GC-MS and sensory evaluation by a trained panel, and positive effects were confirmed by both methods. A further 11 kinds of CEOs were treated via the lipase process and increments of 10% to 1170% were achieved in the proportions of esters, which were mostly ethyl esters...
July 3, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28660077/relationship-between-retinal-nerve-fiber-layer-thickness-and-hemoglobin-present-in-the-optic-nerve-head-in-glaucoma
#5
Marta Gonzalez-Hernandez, Jose Sigut Saavedra, Manuel Gonzalez de la Rosa
PURPOSE: To observe the relationship between topographic hemoglobin levels in the optic nerve head (ONH), the rim thickness (BMO-MRW), and retinal nerve fiber layer (RNFL) thickness. METHODS: 96 normal eyes and 82 glaucomas were examined using TOP strategy (Octopus 300 perimeter), SPECTRALIS OCT, and Laguna ONhE program which estimates hemoglobin from conventional color photographs (Horus Scope DEC 200 fundus camera). RESULTS: The correlation between Laguna ONhE glaucoma discriminant function (GDF) and SPECTRALIS BMO-MRW was R = 0...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28652648/role-of-ph-in-the-recovery-of-bovine-milk-oligosaccharides-from-colostrum-whey-permeate-by-nanofiltration
#6
Joshua L Cohen, Daniela Barile, Yan Liu, Juliana M L N de Moura Bell
Milk oligosaccharides are associated with improved health outcomes in infants. Nanofiltration (NF) is used for isolation of bovine milk oligosaccharides (BMO). The study aim was to improve the recovery of BMO from lactose-hydrolyzed colostrum whey permeate. The retention factors of carbohydrates at various pH and transmembrane pressures were determined for a nanofiltration membrane, which was used at pilot scale to purify BMO. Carbohydrates were quantified by liquid chromatography and characterized using nano-LC-Chip-QToF mass spectrometry...
March 2017: International Dairy Journal
https://www.readbyqxmd.com/read/28650590/intra-and-interobserver-reproducibility-of-bruch-s-membrane-opening-minimum-rim-width-measurements-with-spectral-domain-optical-coherence-tomography
#7
Alexandre S C Reis, Camila E S Zangalli, Ricardo Y Abe, André L Silva, Jayme R Vianna, José Paulo C Vasconcellos, Vital P Costa
PURPOSE: To investigate the reproducibility of Bruch's membrane opening minimum rim width (BMO-MRW) and retinal nerve fibre layer thickness (RNFLT) measurements using spectral domain optical coherence tomography (SD-OCT). Additionally, to investigate the reproducibility of BMO area measurements and fovea to BMO centre (FoBMO) angle. METHODS: Participants were healthy subjects (n = 30) and patients with glaucoma (n = 26). One eye of each participant was scanned to obtain optic nerve head (24 radial B-scans) and peripapillary (one circular B-scan) images by three independent examiners...
June 26, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28620481/tolerability-and-safety-of-the-intake-of-bovine-milk-oligosaccharides-extracted-from-cheese-whey-in-healthy-human-adults
#8
Jennifer T Smilowitz, Danielle G Lemay, Karen M Kalanetra, Elizabeth L Chin, Angela M Zivkovic, Melissa A Breck, J Bruce German, David A Mills, Carolyn Slupsky, Daniela Barile
Mechanistic research suggests a unique evolutionary relationship between complex milk oligosaccharides and cognate bifidobacteria enriched in breast-fed infants. Bovine milk oligosaccharides (BMO) were recently identified as structurally and functionally similar to human milk oligosaccharides. The present single-blind three-way crossover study is the first to determine the safety and tolerability of BMO consumption by healthy human participants (n 12) and its effects on faecal microbiota and microbial metabolism...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/28564701/the-impact-of-lens-opacity-on-sd-oct-retinal-nerve-fiber-layer-and-bruch-s-membrane-opening-measurements-using-the-anatomical-positioning-system-aps
#9
Matthias M Mauschitz, Felix Roth, Frank G Holz, Monique M B Breteler, Robert P Finger
Purpose: To evaluate the impact of lens opacity on retinal nerve fiber layer thickness (RNFLT) and Bruch's membrane opening (BMO) measurements. Methods: Fifty-nine randomly selected patients without any other relevant ocular pathology undergoing elective routine cataract surgery in two specialized eye clinics were enrolled. RNFLT, BMO area, and BMO minimum rim width (BMO-MRW) were assessed with the Heidelberg Engineering Spectralis OCT using the anatomical positioning system (APS) prior to and 1 day after cataract surgery using a ring scan at different eccentricities of the disc (3...
May 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28528295/a-machine-learning-graph-based-approach-for-3d-segmentation-of-bruch-s-membrane-opening-from-glaucomatous-sd-oct-volumes
#10
Mohammad Saleh Miri, Michael D Abràmoff, Young H Kwon, Milan Sonka, Mona K Garvin
Bruch's membrane opening-minimum rim width (BMO-MRW) is a recently proposed structural parameter which estimates the remaining nerve fiber bundles in the retina and is superior to other conventional structural parameters for diagnosing glaucoma. Measuring this structural parameter requires identification of BMO locations within spectral domain-optical coherence tomography (SD-OCT) volumes. While most automated approaches for segmentation of the BMO either segment the 2D projection of BMO points or identify BMO points in individual B-scans, in this work, we propose a machine-learning graph-based approach for true 3D segmentation of BMO from glaucomatous SD-OCT volumes...
May 6, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/28497237/efficacy-of-long-term-nonsteroidal-antiinflammatory-drug-treatment-on-magnetic-resonance-imaging-determined-bone-marrow-oedema-in-early-active-axial-spondyloarthritis-patients
#11
Mei Tang, Leixi Xue, Yueping Shen, Lin Bo, Ru Yang, Jian Wen, Yi Zhang, Zhichun Liu, Jinxiang Fu
To assess the efficacy of long-term treatment with nonsteroidal antiinflammatory drugs (NSAIDs) on bone marrow oedema (BMO) of the sacroiliac joint in newly diagnosed axial spondyloarthritis (SpA) with a symptom duration of less than 4 years, a single-center, open-label study in a cohort of consecutive patients with newly diagnosed axial SpA was conducted. Eligible patients had magnetic resonance imaging (MRI)-determined BMO of the sacroiliac joint at baseline, had a symptom duration of less than 4 years, and were naïve to NSAIDs...
May 11, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28490427/effect-of-acute-intraocular-pressure-elevation-on-the-minimum-rim-width-in-normal-ocular-hypertensive-and-glaucoma-eyes
#12
Sourabh Sharma, Tin A Tun, Mani Baskaran, Eray Atalay, Sri Gowtham Thakku, Zhang Liang, Dan Milea, Nicholas G Strouthidis, Tin Aung, Michael Ja Girard
BACKGROUND: To estimate and compare changes in the Bruch's membrane opening-minimum rim width (BMO-MRW) and area in normal, ocular hypertensive and glaucoma eyes following acute elevations in intraocular pressure (IOP). METHODS: The optic nerve heads (ONHs) of 104 subjects (31 normals, 20 ocular hypertension (OHT) and 53 with primary glaucoma) were imaged using Spectral-domain optical coherence tomography (OCT; Spectralis, Heidelberg Engineering, Germany). IOP was raised twice by applying a force (0...
May 10, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28481929/horizontal-and-vertical-optic-disc-rotation-the-beijing-eye-study
#13
Yuan Yuan Fan, Jost B Jonas, Ya Xing Wang, Chang Xi Chen, Wen Bin Wei
PURPOSE: To measure the optic disc rotation around the vertical and horizontal disc axis and to evaluate associations with general and ocular parameters. DESIGN: Population-based study. METHODS: In the Beijing Eye Study, 3468 participants (mean age:64.6±9.8 years; range:50-93 years) underwent an ophthalmological examination which included spectral-domain optical coherence tomography (OCT) with enhanced depth imaging. Using the OCT images, we determined the amount of the rotation of the optic disc (defined as Bruch´s membrane opening (BMO)) around the vertical axis and horizontal axis...
2017: PloS One
https://www.readbyqxmd.com/read/28469352/riesz-potential-and-its-commutators-on-orlicz-spaces
#14
Vagif S Guliyev, Fatih Deringoz, Sabir G Hasanov
In the present paper, we shall give necessary and sufficient conditions for the strong and weak boundedness of the Riesz potential operator [Formula: see text] on Orlicz spaces. Cianchi (J. Lond. Math. Soc. 60(1):247-286, 2011) found necessary and sufficient conditions on general Young functions Φ and Ψ ensuring that this operator is of weak or strong type from [Formula: see text] into [Formula: see text]. Our characterizations for the boundedness of the above-mentioned operator are different from the ones in (Cianchi in J...
2017: Journal of Inequalities and Applications
https://www.readbyqxmd.com/read/28394809/structure-function-relationship-between-the-bruch-membrane-opening-based-minimum-rim-width-and-visual-field-defects-in-advanced-glaucoma
#15
Serhat Imamoglu, Nimet Burcu Celik, Mehmet S Sevim, Gokhan Pekel, Nimet Yesim Ercalik, Esra Turkseven Kumral, Handan Bardak
PURPOSE: To investigate the relationship between the Bruch membrane opening-minimum rim width (BMO-MRW) (global and temporal) parameters with spectral-domain optical coherence tomography (SD-OCT) and visual field (VF) sensitivity on the 10-2 test in patients with advanced glaucoma. MATERIALS AND METHODS: This cross-sectional, observational study included a total of 33 eyes of 29 patients. To evaluate VF sensitivity, automated white-on-white perimetry was performed using a Humphrey field analyzer...
June 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28391920/antimony-oxidation-and-adsorption-by-in-situ-formed-biogenic-mn-oxide-and-fe-mn-oxides
#16
Yaohui Bai, William A Jefferson, Jinsong Liang, Tingting Yang, Jiuhui Qu
Antimony (Sb), which can be toxic at relatively low concentrations, may co-exist with Mn(II) and/or Fe(II) in some groundwater and surface water bodies. Here we investigated the potential oxidation and adsorption pathways of Sb (III and V) species in the presence of Mn(II) and Mn-oxidizing bacteria, with or without Fe(II). Batch experiments were conducted to determine the oxidation and adsorption characteristics of Sb species in the presence of biogenic Mn oxides (BMOs), which were formed in-situ via the oxidation of Mn(II) by a Mn-oxidizing bacterium (Pseudomonas sp...
April 2017: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/28391369/relationship-between-lamina-cribrosa-displacement-and-trans-laminar-pressure-difference-in-papilledema
#17
Javier García-Montesinos, Francisco J Muñoz-Negrete, Victoria de Juan, Gema Rebolleda
PURPOSE: The purpose of this study was to describe morphological changes in lamina cribrosa (LC), prelaminar tissue thickness (PTT) and Bruch's membrane opening (BMO) in eyes affected by papilledema and correlate them with trans-LC-pressure difference (TLCD). METHODS: This was a prospective study, including twelve eyes newly diagnosed of papilledema. Eyes underwent scanning with Spectralis-OCT with enhanced depth imaging to compare BMO, anterior LC surface position (LC depth-LCD-) and PTT before and after oedema resolution...
April 8, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28387764/crowded-optic-nerve-head-evaluation-with-optical-coherence-tomography-in-anterior-ischemic-optic-neuropathy
#18
S Moghimi, M Afzali, M Akbari, K B Ebrahimi, A Khodabande, A R Yazdani-Abyaneh, S N H Ghafouri, P Coh, S Okhravi, M A Fard
PurposeTo characterize the optic nerve head (ONH) structure in patients with non-arteritic anterior ischemic optic neuropathy (NAION) compared to healthy control subjects using spectral domain optical coherence tomography (SD-OCT) via the enhanced depth imaging method.MethodsIn this prospective, cross-sectional, comparative study, we assessed 66 eyes of 33 patients with unilateral NAION and 31 eyes of 31 healthy normal subjects in an academic institution. The peripapillary nerve fiber layer thickness, disc area, and quantitative parameters of the ONH structures, including the Bruch's membrane opening (BMO) area, anterior laminar depth, and prelaminar thickness and depth were compared between the three groups...
April 7, 2017: Eye
https://www.readbyqxmd.com/read/28376900/an-integrated-strategy-of-biological-and-physical-constraints-in-biological-optimization-for-cervical-carcinoma
#19
Ziwei Feng, Cheng Tao, Jian Zhu, Jinhu Chen, Gang Yu, Shaohua Qin, Yong Yin, Dengwang Li
BACKGROUND: For cervical carcinoma cases, this study aimed to evaluate the quality of intensity-modulated radiation therapy (IMRT) plans optimized by biological constraints. Furthermore, a new integrated strategy in biological planning module was proposed and verified. METHODS: Twenty patients of advanced stage cervical carcinoma were enrolled in this study. For each patient, dose volume optimization (DVO), biological model optimization (BMO) and integrated strategy optimization (ISO) plans were created using same treatment parameters...
April 4, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28353690/impact-of-rates-of-change-of-lamina-cribrosa-and-optic-nerve-head-surface-depths-on-visual-field-progression-in-glaucoma
#20
Zhongheng Wu, Chen Lin, Michael Crowther, Heather Mak, Marco Yu, Christopher K-S Leung
Purpose: To investigate the impact of the rates of change of anterior lamina cribrosa surface depth (ALCSD) and optic nerve head surface depth (ONHSD) on visual field (VF) progression in glaucoma. Methods: One hundred forty-six eyes of 95 glaucoma patients had optical coherence tomography ONH imaging and VF testing at approximately 4-month intervals for greater than or equal to 5 years. Anterior lamina cribrosa surface depth and ONHSD were measured with reference to (1) Bruch's membrane opening (BMO), and (2) choroid-sclera interface (CSI)...
March 1, 2017: Investigative Ophthalmology & Visual Science
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