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https://www.readbyqxmd.com/read/28749241/considerations-for-adhd-in-the-child-with-epilepsy-and-the-child-with-migraine
#1
David W Dunn, Jennifer Downs, Julianne Giust
Attention Deficit Hyperactivity Disorder (ADHD) is a common comorbid condition in children with epilepsy and migraine. Treatment of ADHD in children with epilepsy or migraine is essential but clinicians may overlook symptoms of ADHD and avoid appropriate use of medications that may reduce symptoms of ADHD without compromising treatment of epilepsy or migraine. Areas covered: PubMed was searched for articles on ADHD and epilepsy or migraine. Key papers were reviewed for additional articles. Areas of interest were: epidemiology, etiological factors, and treatment with emphasis on therapy...
July 27, 2017: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/28748680/factors-associated-with-favorable-outcome-of-topiramate-migraine-prophylaxis-in-pediatric-patients
#2
Il Han Yoo, WooJoong Kim, Hunmin Kim, Byung Chan Lim, Hee Hwang, Jong Hee Chae, Jieun Choi, Ki Joong Kim
BACKGROUND AND PURPOSE: There are few studies that have investigated predictive factors related to migraine prophylaxis of which produced inconsistent results. The aim of this study was to identify factors that can predict the treatment response to topiramate prophylaxis in pediatric patients with migraine. METHODS: One hundred and thirteen patients who were older than 7 years and received topiramate for at least 3 months were recruited from the Seoul National University Bundang Hospital outpatient clinic from 2005 to 2014...
July 2017: Journal of Clinical Neurology
https://www.readbyqxmd.com/read/28748672/is-there-an-association-between-migraine-and-gastrointestinal-disorders
#3
REVIEW
Michael Doulberis, Christian Saleh, Stefan Beyenburg
Migraine is a primary episodic headache disorder that represents a substantial burden and disability worldwide. Its pathogenesis is multifactorial and remains hitherto poorly elucidated. An interesting but less-well-known association is that between migraine and gastrointestinal disorders. We have reviewed the literature for relevant papers reporting on the clinical association between migraine and gastrointestinal symptoms. Several studies have shown different gastrointestinal diseases to be associated with migraine, but the underlining pathophysiology remains elusive...
July 2017: Journal of Clinical Neurology
https://www.readbyqxmd.com/read/28748412/pharmacokinetics-of-dfn-15-a-novel-oral-solution-of-celecoxib-versus-celecoxib-400-mg-capsules-a-randomized-crossover-study-in-fasting-healthy-volunteers
#4
Arindam Pal, Srinivas Shenoy, Anirudh Gautam, Sagar Munjal, Jing Niu, Mathangi Gopalakrishnan, Joga Gobburru
BACKGROUND: COX-2 inhibitors can be effective for acute migraine, but none is supplied in a rapidly absorbed, ready-to-use oral liquid formulation. DFN-15, a novel oral liquid formulation of celecoxib, is being developed for the acute treatment of migraine with or without aura. Clinical studies with this formulation are ongoing. OBJECTIVES: The objectives of the present study were to compare the bioavailability of DFN-15 with that of the commercial formulation of celecoxib 400-mg oral capsules (Celebrex(®)) and to determine the dose proportionality of DFN-15 in healthy fasted volunteers...
July 26, 2017: Clinical Drug Investigation
https://www.readbyqxmd.com/read/28748384/the-more-vivid-the-imagination-the-better-the-role-of-the-vividness-of-imagination-in-vasoconstriction-training-and-vasodilatation-training
#5
Julia E Graef, Winfried Rief, Yvonne Nestoriuc, Cornelia Weise
Blood volume pulse biofeedback represents an effective non-pharmacological treatment for migraine. However, the underlying mechanisms of blood volume pulse biofeedback are still unclear. This study investigated the influence of vividness of imagination, private body consciousness, perfectionism, and general self-efficacy on physiological (blood volume pulse amplitude) and psychological (session performance rated by participants and by trainers) success. Changes in skin conductance and skin temperature indicating habituation to training context were examined...
July 26, 2017: Applied Psychophysiology and Biofeedback
https://www.readbyqxmd.com/read/28747203/migraine-and-percutaneous-patent-foramen-ovale-closure-a-systematic-review-and-meta-analysis
#6
Yu-Jie Shi, Jun Lv, Xing-Ting Han, Guo-Gang Luo
BACKGROUND: The association between patent foramen ovale (PFO) and migraine with aura (MA) is well established. However, the benefits of PFO closure are less certain in patients with migraine without aura (MwoA). METHODS: We systematically searched Pubmed for pertinent clinical studies published from January 2000 to July 2015. The primary end-point was the elimination or significant improvement of migraine symptoms after PFO closure. RESULTS: Upon screening an initial list of 315 publications, we identified eight studies that included 546 patients...
July 26, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28747114/prevalence-characteristics-and-management-of-headache-experienced-by-people-with-schizophrenia-and-schizoaffective-disorder-a-cross-sectional-cohort-study
#7
Joanne Connaughton, Benedict Wand
OBJECTIVES: Headache is the most common type of pain reported by people with schizophrenia. This study aimed to establish prevalence, characteristics and management of these headaches. METHODS: One hundred participants with schizophrenia/schizoaffective disorder completed a reliable and valid headache questionnaire. Two clinicians independently classified each headache as migraine, tension-type, cervicogenic or other. RESULTS: The 12-month prevalence of headache (57%) was higher than the general population (46%) with no evidence of a relationship between psychiatric clinical characteristics and presence of headache...
August 2017: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/28746431/id-migraine%C3%A2-questionnaire-and-accurate-diagnosis-of-migraine
#8
Ana Carolina Musser Tavares de Mattos, Jano Alves de Souza, Pedro Ferreira Moreira, Mauro Eduardo Jurno, Luis Guilhermo Coca Velarde
Objective: To analyze the applicability of the Portuguese version of ID-MigraineTM in a sample of Brazilian patients. Methods: Patients with headache were recruited from the neurology outpatient clinic of a tertiary hospital and submitted to the ID-MigraineTM questionnaire. The diagnosis of headache was made according to the ICHD-2 criteria. Results: Of the 232 patients, 86% had migraine. The questionnaire showed a sensitivity of 92% (95%CI, 88% to 95%), specificity of 60% (95%CI, 43% to 77%) and a positive predictive value of 93% (95%CI, 89% to 96%)...
July 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28745187/fresh-focus-on-stroke-care
#9
Catharine Sadler
When 36-year-old company director Nathan Ridgard went to the emergency department with an excruciating headache and neck pain he was told he had a severe migraine and was admitted for tests.
July 26, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28744704/subjective-cognitive-decline-in-patients-with-migraine-and-its-relationship-with-depression-anxiety-and-sleep-quality
#10
Sun Hwa Lee, Yeonwook Kang, Soo-Jin Cho
BACKGROUND: Cognitive decline is a major concern in patients with migraine. Depression, anxiety, and/or poor sleep quality are well-known comorbidities of migraine, but available evidence on the subjective cognitive decline (SCD) is limited. This study aimed to investigate the presence and frequency of SCD and its relationship with anxiety, depression and sleep quality in patients with migraine. METHODS: We enrolled patients with migraine who scored within the normal range of the Korean-Mini Mental State Examination and the Korean-Montreal Cognitive Assessment...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28743296/case-report-of-hypnic-headache-a-rare-headache-disorder-with-nocturnal-symptoms
#11
Kanishka P Dissanayake, Damindi P Wanniarachchi, Udaya K Ranawaka
BACKGROUND: Headache is one of the commonest complaints reported to physicians worldwide. Yet, arriving at the proper diagnosis can be a challenge in many patients. Although most headaches belong to common categories of migraine and tension-type headache, which are diagnosed and managed relatively easily, several uncommon headache disorders can lead to delays in diagnosis. Certain medications are more efficacious than others in managing these headache disorders, hence establishing the correct diagnosis is of paramount importance...
July 25, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28742261/the-clinical-characteristics-and-audiogram-in-103-meniere-disease-patients-with-and-without-vestibular-migraine
#12
Yixu Wang, Tongxiang Diao, Yixin Zhao, Lisheng Yu
1 There was a close relationship between MD and VM. 48 MD patients(46.6%) had VM, 18 MD patients (17.5%)were probable to have VM. 2 MD patients with VM have better hearing than those without VM at 500 Hz, 1000Hz, and 2000Hz. 3 Among MD patients with VM, the mean monthly frequency of vertigo attack was 7.1,which can differ significantly from those among MD patients with probable VM and those without VM.(P<0.01). 4 The female MD patients were 7.92 times to have VM than male MD patients(95% CI, 2.97 to 21.08; P=0...
July 25, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28742242/multidisciplinary-team-treatment-approaches-to-chronic-daily-headaches
#13
Soma Sahai-Srivastava, Erica Sigman, Ashley Uyeshiro Simon, Lyssa Cleary, Lori Ginoza
OBJECTIVE: In this review, we focus on nonmedication treatment approaches to chronic daily headaches and chronic migraine. We review the current scientific data on studies using multimodal treatments, especially physical therapy and occupational therapy, and provide recommendations on the formation of interdisciplinary headache teams. BACKGROUND: Chronic daily headache, which includes chronic migraine, is a particularly challenging clinical entity which often involves multiple headache types and comorbidities...
July 25, 2017: Headache
https://www.readbyqxmd.com/read/28742215/complementary-and-alternative-medicine-use-among-us-adults-with-headache-or-migraine-results-from-the-2012-national-health-interview-survey
#14
Yan Zhang, Jeff A Dennis, Matthew J Leach, Felicity L Bishop, Holger Cramer, Vincent C H Chung, Craig Moore, Romy Lauche, Ron Cook, David Sibbritt, Jon Adams
BACKGROUND: Given the safety concerns regarding pharmacological agents, and the considerable impact of headache and migraine on the sufferer's quality of life, many people seek other treatment options beyond conventional medication and care to address their symptoms; this includes complementary and alternative medicine (CAM). Some CAM interventions have shown promising results in clinical trials of headache and migraine management. Nonetheless, there has been little research exploring the reasons for using CAM, and the types of CAM used, among this population...
July 25, 2017: Headache
https://www.readbyqxmd.com/read/28741429/rapid-systemic-delivery-of-zolmitriptan-using-an-adhesive-dermally-applied-microarray
#15
Donald J Kellerman, Mahmoud Ameri, Stewart J Tepper
Adhesive Dermally-Applied Microarray (ADAM) is a device for intracutaneous drug administration consisting of a 3 cm(2) disposable array of drug-coated titanium microprojections on an adhesive backing. It is applied using a low cost, reusable, handheld applicator. Microprojections penetrate the stratum corneum, delivering drug proximal to capillaries with limited likelihood of pain. The pharmacokinetics of zolmitriptan delivery using ADAM was evaluated in 20 healthy volunteers. Median tmax was <20 min, comparable to subcutaneous sumatriptan...
July 25, 2017: Pain Management
https://www.readbyqxmd.com/read/28741118/strategies-to-decrease-injection-site-pain-in-botulinum-toxin-therapy
#16
Lejla Paracka, Katja Kollewe, Florian Wegner, Dirk Dressler
Botulinum toxin is now used for numerous indications including dystonias, spasticity, cerebral palsy, hyperhidrosis, cosmetics and chronic migraine. It has to be injected into its target tissues thus causing injection site pain. We wanted to compare the efficacy of various analgesic interventions suggested for reduction of injection site pain. In 13 healthy controls, pain thresholds in the fingertips II and III bilaterally were determined by the Mechanical Pain Threshold Test and the Repetitive Pain Stimulation Test at baseline and under nitrous oxide/oxygen, ice spray, local anaesthetic cream and forearm ischaemia...
July 24, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/28741060/efficacy-of-modified-wuzhuyu-decoction-granule-for-migraine-patients-with-cold-and-stasis-obstructing-meridian-syndrome-a-randomized-double-blind-placebo-controlled-trial
#17
Hong-Wei Liu, Yi-Huai Zou, Ke-Gang Cao, Li-Hua Yu, Yong Zhang, Cai-Hong Fu, Da-Yong Ma
OBJECTIVE: To study the efficacy of modified Wuzhuyu Decoction Granule (, MWDG) in the treatment of migraine patients with cold and stasis obstructing meridian syndrome. METHODS: This study was a randomized, double-blind, placebo-controlled trial. A total of 78 migraine patients with cold and stasis obstructing meridian syndrome were recruited and randomly assigned by a ratio of 2:1 into a treatment group (51 cases) and a placebo group (27 cases). Patients in the treatment group were treated with MWDG while placebo granules were applied in the control group...
July 25, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28740841/migrainous-infarction-a-rare-and-often-overlooked-diagnosis
#18
REVIEW
Gabriel Afonso Dutra Kreling, Neuro Rodrigues de Almeida, Pedro José Dos Santos
Migraine is a neurological entity and a well-known independent risk factor for cerebral infarction, which mostly afflicts the young female population. Researching focal neurological signs in this subset of the population with the diagnosis of a neurological ischemic event should always take into account the migraine as the etiology or as an associated factor. The etiology of central nervous system (CNS) ischemia is considerable. Migraine, although rare, also may be included in this vast etiological range, which is called migrainous infarction...
April 2017: Autopsy & case reports
https://www.readbyqxmd.com/read/28738691/selective-cephalic-upregulation-of-p-erk-camkii-and-p-creb-in-response-to-glyceryl-trinitrate-infusion
#19
Roshni Ramachandran, Sara Hougaard Pedersen, Dipak Vasantrao Amrutkar, Steffen Petersen, Julie Mie Jacobsen, Anders Hay-Schmidt, Jes Olesen, Inger Jansen-Olesen
Background A common characteristic of migraine-inducing substances is that they cause headache and no pain in other areas of the body. Few studies have compared pain mechanisms in the trigeminal and spinal systems and, so far, no major differences have been noted. We compared signalling molecules in the trigeminal and spinothalamic system after infusion of the migraine-provoking substance glyceryltrinitrate. Method A catheter was placed in the femoral vein of rats and one week later glyceryltrinitrate 4 µg/kg/min was infused for 20 min...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28738690/magnetic-resonance-imaging-in-children-presenting-migraine-with-aura-association-of-hypoperfusion-detected-by-arterial-spin-labelling-and-vasospasm-on-mr-angiography-findings
#20
Domitille Cadiot, Romain Longuet, Bertrand Bruneau, Catherine Treguier, Aline Carsin-Vu, Isabelle Corouge, Constantin Gomes, Maïa Proisy
Objective A child presenting with a first attack of migraine with aura usually undergoes magnetic resonance imaging (MRI) to rule out stroke. The purpose of this study was to report vascular and brain perfusion findings in children suffering from migraine with aura on time-of-flight MR angiography (TOF-MRA) and MR perfusion imaging using arterial spin labelling (ASL). Methods We retrospectively included all children who had undergone an emergency MRI examination with ASL and TOF-MRA sequences for acute neurological deficit and were given a final diagnosis of migraine with aura...
January 1, 2017: Cephalalgia: An International Journal of Headache
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