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Thyroid ablation

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https://www.readbyqxmd.com/read/28910916/-primary-tracheal-malignant-glomus-tumor-with-lung-metastasis-diagnosed-by-pathological-analysis-a-case-report-and-literature-review
#1
B Huang, F G Chen, J Zhuang, W C Zheng, W Y Zhu, Q C Zhang, S H Wang, C M Guo, C M Xie
Objective: To study the clinical manifestations, pathological features, diagnosis, differential diagnosis, treatment and prognosis of primary tracheobronchial or pulmonary malignant glomus tumor (MGT). Methods: A case of primary tracheal MGT with lung metastasis diagnosed by pathological analysis admitted to Affiliated Shantou Hospital of Sun Yat-sen University in May. 2015 was analyzed, and the related literatures were reviewed. We searched databases including PubMed, Embase, Ovid, Cochrane, Wanfang and Chinese National Knowledge infrastructure (CNKI), using the keyword "tracheal or bronchial or pulmonary malignant glomus tumor" from Jan...
September 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28894936/thermal-ablation-of-thyroid-nodules-are-radiofrequency-ablation-microwave-ablation-and-high-intensity-focused-ultrasound-equally-safe-and-effective-methods
#2
Yücel Korkusuz, Daniel Gröner, Natascha Raczynski, Oleg Relin, Yasmina Kingeter, Frank Grünwald, Christian Happel
OBJECTIVES: This study compares volume reduction of benign thyroid nodules three months after Radiofrequency Ablation (RFA), Microwave Ablation (MWA) or High Intensity Focused Ultrasound (HIFU) to evaluate which of these methods is the most effective and safe alternative to thyroidectomy or radioiodine therapy. MATERIAL AND METHODS: Ninety-four patients (39 male, 55 female) with a total of 118 benign, symptomatic thyroid nodules were divided into three subgroups...
September 11, 2017: European Radiology
https://www.readbyqxmd.com/read/28877833/effect-of-lymph-node-metastasis-on-change-of-positive-thyroglobulin-antibody-in-differentiated-thyroid-carcinoma-after-initial-treatment
#3
Teng Zhang, Li-Ping Song, Teng Zhao, Wen Gao, Yan-Song Lin
Objective To investigate the influence of lymph node metastasis on the change of positive thyroglobulin antibody(TgAb)in differentiated thyroid carcinoma after initial treatment.Methods We retrospectively analyzed the clinical data of 98 differentiated thyroid carcinoma patients with positive TgAb(≥115 IU/ml)before radioiodine(RAI)therapy.All of whom underwent total or near total thyroidectomy,neck lymph node dissection,and subsequent RAI therapy.Patients were divided into negative group(n=83)and non-negative group(n=15)according to the disappearance of positive TgAb or not after a mean follow-up of 21...
August 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/28868259/radioiodine-ablation-following-thyroidectomy-for-differentiated-thyroid-cancer-literature-review-of-utility-dose-and-toxicity
#4
REVIEW
Nicholas S Andresen, John M Buatti, Hamed H Tewfik, Nitin A Pagedar, Carryn M Anderson, John M Watkins
Management recommendations for differentiated thyroid cancer are evolving. Total thyroidectomy is the backbone of curative-intent therapy, with radioiodine ablation (RAI) of the thyroid remnant routinely performed, in order to facilitate serologic surveillance and reduce recurrence risk. Several single-institution series have identified patient subsets for whom recurrence risk is sufficiently low that RAI may not be indicated. Further, the appropriate dose of RAI specific to variable clinicopathologic presentations remains poorly defined...
July 2017: European Thyroid Journal
https://www.readbyqxmd.com/read/28860813/low-versus-high-radioiodine-activity-for-ablation-of-the-thyroid-remnant-after-thyroidectomy-in-han-chinese-with-low-risk-differentiated-thyroid-cancer
#5
Rong-Bin Lv, Qing-Gang Wang, Chao Liu, Fang Liu, Qing Zhao, Jian-Guo Han, Dao-Ling Ren, Bin Liu, Cheng-Li Li
AIM: The aim of this study was to compare the efficacy and adverse effects of radioiodine ((131)I) therapy between two groups of patients with low-risk differentiated thyroid cancer (DTC) who received 30 mCi or 100 mCi radioiodine for ablation of the thyroid remnant after total thyroidectomy. METHODS: The study cohort was 173 patients, 85 of whom were given 30 mCi of radioiodine and the others were given 100 mCi of radioiodine. Follow-up involved neck ultrasonography, measurement of serum levels of thyroglobulin and whole-body scans to evaluate the response of radioiodine treatment...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/28856610/use-of-low-dose-radioiodine-ablation-for-graves-orbitopathy-results-of-a-pilot-perspective-study-in-a-small-series-of-patients
#6
M Leo, E Sabini, I Ionni, A Sframeli, B Mazzi, F Menconi, E Molinaro, F Bianchi, F Brozzi, P Santini, R Elisei, M Nardi, P Vitti, C Marcocci, M Marinò
OBJECTIVE: Elimination of thyroid antigens by total thyroid ablation (TTA), namely, thyroidectomy followed by radioiodine, may be beneficial for Graves' Orbitopathy (GO). TTA is usually performed with a (131)I dose of 30 mCi. In Italy, this dose must be followed by a 24-h protected hospitalization, with increase in the waiting lists. In contrast, a 15 mCi dose can be given without hospitalization and with lower costs. Here, we investigated whether a lower dose of radioiodine can be used to ablate thyroid remnants in patients with GO, after thyroidectomy...
August 30, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28855431/us-guided-percutaneous-microwave-ablation-for-the-treatment-of-benign-thyroid-nodules
#7
Wenjun Wu, Xiaohua Gong, Qi Zhou, Xiong Chen, Xiaojun Chen, Bimin Shi
The aim of this study was to define the effectiveness and safety of ultrasound(US)-guided percutaneous microwave ablation(MWA) for benign thyroid nodules with one session treatment. A total 121 benign thyroid nodules in 100 euthyroid patients underwent MWA in one medical center between August 2014 and December 2015. MWA was performed with an internally cooled antenna under local anesthesia. The volume of the nodule, cosmetic score and symptom score were compared before and after the procedure. The volume reduction rate(VRR) was also evaluated...
August 29, 2017: Endocrine Journal
https://www.readbyqxmd.com/read/28844832/radiofrequency-ablation-in-the-treatment-of-benign-thyroid-nodules-an-efficient-and-safe-alternative-to-surgery
#8
Rosa Cervelli, Salvatore Mazzeo, Luigi De Napoli, Antonio Boccuzzi, Benedetta Pontillo-Contillo, Gabriele Materazzi, Paolo Miccoli, Roberto Cioni, Davide Caramella
PURPOSE: To evaluate the efficacy and safety of radiofrequency (RF) ablation in the treatment of benign thyroid nodules (BTNs) by applying a modification of the moving-shot technique. MATERIALS AND METHODS: Fifty-one BTNs in 46 patients for whom surgery was contraindicated or who refused surgery were treated with RF ablation: 31 had lesion volumes < 20 cm(3) (group A) and 20 had volumes ≥ 20 cm(3) (group B). The solid component percentage of each lesion was assessed, and any present fluid component was aspirated...
August 24, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28844602/further-investigation-on-high-intensity-focused-ultrasound-hifu-treatment-for-thyroid-nodules-effectiveness-related-to-baseline-volumes
#9
Michael Sennert, Christian Happel, Yücel Korkusuz, Frank Grünwald, Björn Polenz, Daniel Gröner
RATIONALE AND OBJECTIVES: Several minimally invasive thermal techniques have been developed for the treatment of benign thyroid nodules. A new technique for this indication is high-intensity focused ultrasound (HIFU). The aim of this study was to assess effectiveness in varying preablative nodule volumes and whether outcome patterns that were reported during studies with other thermal ablative procedures for thyroid nodule ablation would also apply to HIFU. MATERIALS AND METHODS: Over the last 2 years, 19 nodules in 15 patients (12 women) whose average age was 58...
August 23, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28842651/us-guided-percutaneous-radiofrequency-versus-microwave-ablation-for-benign-thyroid-nodules-a-prospective-multicenter-study
#10
Zhigang Cheng, Ying Che, Songyuan Yu, Shurong Wang, Dengke Teng, Huixiong Xu, Jianwei Li, Desheng Sun, Zhiyu Han, Ping Liang
Compared with microwave ablation (MWA), percutaneous radiofrequency ablation (RFA) and laser ablation (LA) have been recommended as minimally invasive treatments for patients with symptomatic benign thyroid nodules (BTNs) because of the large number of clinical applications. This prospective multicenter study sought to evaluate the clinical outcomes of RFA and MWA for BTNs. In eight participating institutions, the total number of 1252 patients treated by RFA and MWA were 649 ones with 687 BTNs and 603 ones with 664 BTNs, respectively...
August 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28834790/comparison-of-treatment-efficacy-1-and-2-years-after-thyroid-remnant-ablation-with-1110-versus-5550%C3%A2-mbq-of-iodine-131-in-patients-with-intermediate-risk-differentiated-thyroid-cancer
#11
Atena Aghaei, Narjess Ayati, Susan Shafiei, Bita Abbasi, S Rasoul Zakavi
BACKGROUND: Radioiodine ablation may be associated with improved survival in patients with intermediate-risk follicular cell differentiated thyroid cancer (FCDTC). The aim of this study was to compare ablation efficacy of 1110 versus 5500 MBq of iodine-131 (I) in FCDTC patients with intermediate risk. METHODS: Thirty-nine patients with intermediate-risk FCDTC (T3N0, T1-2N1b and T1-3N1a) were treated with 1110 MBq of I and compared with 43 age-matched and sex-matched patients who received 5550 MBq of I...
August 22, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28832376/low-dose-radioactive-iodine-ablation-is-sufficient-in-patients-with-small-papillary-thyroid-cancer-having-minor-extrathyroidal-extension-and-central-lymph-node-metastasis-t3-n1a
#12
Minjung Seo, Yon Seon Kim, Jong Cheol Lee, Myung Woul Han, Eun Sook Kim, Kyung Bin Kim, Seol Hoon Park
PURPOSE: The aim of this study was to evaluate the effectiveness of low-dose radioactive iodine (RAI) ablation in patients with small papillary thyroid cancer (PTC) exhibiting microscopic extrathyroidal extension (mETE) and central lymph node (CLN) metastasis. METHODS: Among patients who underwent RAI ablation between March 2007 and February 2014, those who had small PTCs (≤2 cm), as well as mETE and CLN metastasis (T3 N1a M0), were enrolled. Response to ablation and long-term outcomes were assessed and compared according to the administered RAI dose...
August 21, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28831826/factors-related-to-the-recurrence-of-benign-thyroid-nodules-after-thermal-ablation
#13
Jung Hwan Baek
No abstract text is available yet for this article.
August 23, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28816214/synchronous-malignancies-of-thyroglossal-duct-cyst-and-thyroid-gland
#14
Chinna Naik, Sandip Basu
Malignant involvement of thyroglossal duct cyst is rare, still rarer is the synchronous malignant involvement of the thyroid gland. Although the Sistrunk procedure is often regarded as adequate, controversy exists of the need for an additional total thyroidectomy and radioiodine ablative therapy, the decision of which depends upon the presence of (i) suspicious thyroid gland nodule; (ii) presence of lymphadenopathy; or (iii) a previous history of neck irradiation. We report a 47-year-old woman diagnosed with papillary carcinoma within a recurrent thyroglossal duct cyst with infiltration into surrounding soft tissues and a suspicious thyroid nodule of the left thyroid lobe with no regional lymph node involvement...
March 2017: National Medical Journal of India
https://www.readbyqxmd.com/read/28811719/refractory-hepatic-encephalopathy-in-a-patient-with-hypothyroidism-another-element-in-ammonia-metabolism
#15
Fernando Díaz-Fontenla, Marta Castillo-Pradillo, Arantxa Díaz-Gómez, Luis Ibañez-Samaniego, Pilar Gancedo, Juan Adan Guzmán-de-Villoria, Pilar Fernández-García, Rafael Bañares-Cañizares, Rita García-Martínez
Hepatic encephalopathy (HE) remains a diagnosis of exclusion due to the lack of specific signs and symptoms. Refractory HE is an uncommon but serious condition that requires the search of hidden precipitating events (i.e., portosystemic shunt) and alternative diagnosis. Hypothyroidism shares clinical manifestations with HE and is usually considered within the differential diagnosis of HE. Here, we describe a patient with refractory HE who presented a large portosystemic shunt and post-ablative hypothyroidism...
July 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28806348/radioprotective-effect-of-vitamin-e-on-salivary-glands-after-radioiodine-therapy-for-differentiated-thyroid-cancer-a-randomized-controlled-trial
#16
Arun Upadhyaya, Pingping Zhou, Zhaowei Meng, Peng Wang, Guizhi Zhang, Qiang Jia, Jian Tan, Xue Li, Tianpeng Hu, Na Liu, Sen Wang, Xiaoxia Liu, Huiying Wang, Chunmei Zhang, Fengxiao Zhao, Ziyu Yan, Xiaoran Wang, Xuemeng Zhang, Wan Zhang
OBJECTIVES: This study aimed to examine the radioprotective effect of vitamin E on salivary glands after radioactive iodine (I) therapy in patients with differentiated thyroid cancer. PATIENTS AND METHODS: Eighty-two patients with differentiated thyroid cancer were enrolled in this study. They were divided randomly into four groups (control group: 22 cases, group A: 23 cases, group B: 22 cases, and group C: 15 cases) before postsurgical ablation therapy with 100 mCi I...
August 11, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28797186/ethanol-and-thermal-ablation-for-malignant-thyroid-tumours
#17
So Yeong Jeong, Jung Hwan Baek, Young Jun Choi, Jeong Hyun Lee
Papillary thyroid carcinoma (PTC) is the most common subtype of thyroid malignancy and has a good prognosis and low mortality rate. Surgery is the standard treatment for patients with primary and recurrent thyroid cancer. Although patients with PTC usually exhibit excellent treatment outcome, the incidence of recurrence in the neck ranges from 20% to 59%. When a patient with thyroid cancer is contraindicated for surgery, ultrasound (US)-guided ablation techniques, including ethanol ablation (EA) and thermal ablations, are suggested alternatives...
August 11, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28793806/the-percentage-of-serum-thyroglobulin-rise-in-the-first-week-did-not-predict-the-eventual-success-of-high-intensity-focussed-ablation-hifu-for-benign-thyroid-nodules
#18
Brian H H Lang, Yu Cho Woo, Keith W H Chiu
BACKGROUND: Given that high-intensity focussed ultrasound (HIFU) of benign thyroid nodules often causes a massive release of thyroglobulin (Tg) into the circulation, we hypothesised a greater initial Tg rise may result in a greater nodule shrinkage 6 months after ablation. METHODS: One hundred and five patients who underwent HIFU for symptomatic benign thyroid nodule from 2015 to 2016 were analysed. Serum Tg and anti-Tg autoantibody were checked on treatment day (baseline) and 4 d after treatment...
August 10, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28791923/disease-severity-at-presentation-in-patients-with-disease-related-mortality-from-differentiated-thyroid-cancer-implications-for-the-2015-ata-guidelines
#19
Eyal Robenshtok, Yuval Nachalon, Carlos Benbassat, Dania Hirsch, Ilan Shimon, Alon Grossman, Talia Diker-Cohen, Amit Akirov, Aharon Popovtzer
BACKGROUND: The current trend of less aggressive treatment of low-risk differentiated thyroid cancer (DTC) patients was recently challenged by a study reporting >10% disease-related mortality (DRM) in low-risk patients ablated with radioiodine activities below 54 mCi. However, this study and others were limited by incomplete data on disease severity at presentation. Whether patients presenting with low-risk disease are at risk for disease-related mortality is crucial for planning current treatment strategies...
September 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28782127/crucial-parameters-in-thyroid-carcinoma-reporting-challenges-controversies-and-clinical-implications
#20
Bin Xu, Ronald Ghossein
In the modern era, a pathology report of thyroid carcinoma requires the inclusion of numerous prognostically relevant histopathologic features, e.g. the presence and extent of vascular and capsular invasion, extrathyroidal extension, the surgical margin status, and the characteristics of nodal metastasis. These pathologic features are crucial components of the initial risk stratification to determine the need for completion thyroidectomy and/or post-operative radioactive iodine ablation therapy. The current review aims to summarize the diagnostic criteria, the controversies, the prognostic impacts, and the challenges of these pathologic characteristics, focusing specifically on the parameters that are incorporated into the American Joint Committee on Cancer (AJCC) staging system, College of American Pathologists (CAP) reporting template, American Thyroid Association (ATA), and National Comprehensive Cancer Network (NCCN) guidelines...
August 7, 2017: Histopathology
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