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Thyroid ablation

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https://www.readbyqxmd.com/read/29331885/autonomously-hyperfunctioning-cystic-nodule-harbouring-thyroid-carcinoma-case-report-and-literature-review
#1
Maria João Lima, Virgínia Soares, Pedro Koch, Artur Silva, António Taveira-Gomes
INTRODUCTION: Hyperthyroidism is rarely associated with malignancy, but it cannot rule out thyroid cancer. Although there is published data describing this coexistence, thyroid carcinomas inside autonomously functioning nodules are uncommon. PRESENTATION OF CASE: A 49-year-old woman presented with a cervical mass, unexplained weight loss and anxiousness, sweating and insomnia. On physical examination, she had a palpable left thyroid nodule. Thyroid function tests showed suppressed TSH (<0,1 uUI/mL), thyroxine 1,44 ng/dL (normal range 0,70-1,48) and triiodothyronine 4,33 pg/mL (normal range 1,71-3,71)...
January 8, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29330630/evaluation-of-pain-during-high-intensity-focused-ultrasound-ablation-of-benign-thyroid-nodules
#2
Brian H H Lang, Yu-Cho Woo, Keith Wan-Hang Chiu
OBJECTIVE: To assess severity and factors of pain during high-intensity focused ultrasound (HIFU) ablation of benign thyroid nodules. METHODS: 128 patients who underwent a HIFU ablation for a benign thyroid nodule were analysed. All patients received a bolus of intravenous pethidine and diazepam before treatment. After treatment, patients were asked to rate their overall pain experience on a visual analogue scale (0-100) (0 = no pain; 100 = worse possible pain) during treatment, 2 h after treatment and the following morning...
January 12, 2018: European Radiology
https://www.readbyqxmd.com/read/29325506/clinical-impact-of-detectable-antithyroglobulin-antibodies-below-the-reference-limit-borderline-in-patients-with-papillary-thyroid-carcinoma-with-negative-serum-thyroglobulin-and-neck-ultrasonography-after-ablation-a-prospective-study
#3
Marina Carvalho, Pedro Weslley Rosario, Gabriela Franco Mourão, Luis Fernando Faria Oliveira, Maria Regina Calsolari
BACKGROUND: Interference of antithyroglobulin antibodies (TgAb) with serum thyroglobulin (Tg) can occur even at detectable TgAb concentrations below the reference limit (borderline TgAb). Thus, borderline TgAb is considered positive TgAb in patients with thyroid cancer. This prospective study evaluated patients with papillary thyroid carcinoma with negative Tg and neck ultrasonography (US) after initial therapy and compared tumor persistence/recurrence and long-term Tg and TgAb behavior in those with borderline versus undetectable TgAb...
January 12, 2018: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29324909/effect-of-hypoparathyroid-on-bone-mineral-density-of-lumber-spine-in-postmenopausal-women-with-differentiated-thyroid-cancinoma
#4
Yongli Bai, Yanlei Huo, Fei Yu, Danyang Wang, Chao Ma
OBJECTIVE: To investigate the effect of hypoparathyroid on bone mineral density in postmenopausal women with differentiated thyroid carcinoma (DTC). SUBJECT AND METHODS: Postmenopausal women with postoperative DTC, and undergoing thyroid residual ablation or for metastases treatment were collected and followed for two years. They were divided into hypoparathyroid group (PTH<15pg/mL) and a normal cognitive group (PTH>15pg/mL). Bone mineral density (BMD) at the lumbar spine was analyzed using dual-energy X-ray absorptiometry (DXA) at baseline, 6, 12 and 24 months...
September 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/29323252/clinical-value-of-99mtc-3prgd2-spect-ct-in-differentiated-thyroid-carcinoma-with-negative-131i-whole-body-scan-and-elevated-thyroglobulin-level
#5
Rui Gao, Guang-Jian Zhang, Yuan-Bo Wang, Yan Liu, Fan Wang, Xi Jia, Yi-Qian Liang, Ai-Min Yang
The aim of this study was to assess the usefulness of integrin imaging with 99mTc-PEG4-E[PEG4-c(RGDfK)]2 (99mTc-3PRGD2) single photon emission computed tomography (SPECT)/computed tomography (CT) in detecting recurrent disease in patients with differentiated thyroid cancer (DTC), negative radioiodine whole-body scan (WBS) and high serum thyroglobulin (Tg). Thirty-seven patients who underwent total thyroidectomy followed by radioactive iodine ablation and had negative radioiodine WBS but elevated Tg levels were included...
January 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29322881/radiofrequency-ablation-of-primary-thyroid-carcinoma-efficacy-according-to-the-types-of-thyroid-carcinoma
#6
So Yeong Jeong, Jung Hwan Baek, Young Jun Choi, Sae Rom Chung, Tae Yon Sung, Won Gu Kim, Tae Yong Kim, Jeong Hyun Lee
OBJECTIVE: To evaluate the efficacy of ultrasound (US)-guided radiofrequency ablation (RFA) according to the types of thyroid carcinoma, particularly in patients with a high surgical risk. MATERIALS AND METHODS: Eight patients with nine tumors of pathologically proven papillary and anaplastic carcinoma were treated by US-guided RFA. Patients with primary thyroid carcinoma were divided into three groups; group 1: Anaplastic carcinoma, group 2: papillary macrocarcinoma, and group 3: papillary microcarcinoma...
January 11, 2018: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/29316865/effects-of-thyroid-stimulating-hormone-on-peripheral-thyroid-hormone-metabolism-and-serum-lipids
#7
Carolien M Beukhof, Elske Theresia Massolt, Theo J Visser, Tim Korevaar, Marco Medici, Wouter W de Herder, Jeanine Roeters van Lennep, Monique Mulder, Yolanda B de Rijke, Christoph Reiners, Frederik A Verburg, Robin Peeters
BACKGROUND: Subclinical hypothyroidism is associated with dyslipidemia and atherosclerosis. Whether part of these effects are mediated via direct effects of TSH on peripheral TH metabolism and/or concentrations of serum lipids is not clear. OBJECTIVE: To examine whether thyroid stimulating hormone (TSH) has direct effects on peripheral thyroid hormone (TH) metabolism and serum lipids. METHODS: We retrospectively analyzed 82 patients with differentiated thyroid cancer...
January 9, 2018: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29313120/significance-of-hyperechoic-marks-observed-during-high-intensity-focused-ultrasound-hifu-ablation-of-benign-thyroid-nodules
#8
Brian H H Lang, Yu-Cho Woo, Keith Wan-Hang Chiu
OBJECTIVE: To examine the association between the appearance of hyperechoic marks (HEMs) during high-intensity focused ultrasound (HIFU) ablation of benign thyroid nodules and nodule shrinkage at 6 months. METHODS: One hundred and thirty-six patients who underwent HIFU for benign thyroid nodule were analysed. An independent person carefully examined the B-mode ultrasonography screen for the appearance of HEMs after each pulse. The proportion of HEMs (%) was calculated by: [(Number of pulses that resulted in HEMs) / (Total number of pulses given per treatment) × 100] while the nodule shrinkage was measured by volume reduction ratio (VRR) = [Baseline volume-volume at 6 months]/[Baseline volume] * 100...
January 8, 2018: European Radiology
https://www.readbyqxmd.com/read/29310383/ectopic-papillary-thyroid-carcinoma-within-a-thyroglossal-duct-cyst-a-case-report
#9
Natascha Roehlen, Szilvia Takacs, Olaf Ebeling, Jochen Seufert, Katharina Laubner
RATIONALE: Ectopic thyroid carcinoma within a thyroglossal duct cyst (TGDCCa) is an extremely rare entity. Thus, there is no unified appropriate therapeutic strategy, and individual approaches are controversial. PATIENTS CONCERNS: We report the case of a 21-year old woman who underwent Sistrunk procedure for a thyroglossal duct cyst (TGDC). DIAGNOSES: During histological evaluation of the resected TGDC a papillary thyroid carcinoma was found...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29306930/management-of-thyrotoxicosis-in-children-and-adolescents-35-years-experience-in-304-patients
#10
Fereidoun Azizi, Atieh Amouzegar
BACKGROUND: Diffuse toxic goiter accounts for about 15% of all childhood thyroid diseases. There is great controversy over the management of Graves' disease in children and adolescents. This article reports our experience in 304 children and juvenile patients with Graves' disease. METHODS: Between 1981 and 2015, 304 patients aged 5-19 years with diffuse toxic goiter were studied, of whom 296 patients were treated with antithyroid drugs (ATD) for 18 months. Patients with persistent or relapsed hyperthyroidism who refused ablative therapy with surgery or radioiodine were managed with continuous methimazole (MMI) treatment...
January 8, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29303011/sonographic-measurement-of-thyroid-nodule-changes-after-microwave-ablation-relationship-between-multiple-parameters
#11
Ying Wei, Linxue Qian, Ji-Bin Liu, Yujiang Liu
OBJECTIVE: Microwave ablation (MWA) is an effective technique for the treatment of benign thyroid nodules. The aim of this study was to investigate whether it is necessary to study changes in variables other than the volume reduction between follow-up intervals. This study also introduced the index R (Ssurface/V) to explore whether it could reflect features of shape between follow-up intervals. MATERIALS AND METHODS: A total of 236 complex benign thyroid nodules in 230 patients who underwent MWA in our department from October 2013 to February 2017 were included...
January 5, 2018: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/29302874/anti-m%C3%A3-llerian-hormone-in-pre-menopausal-females-after-ablative-radioiodine-treatment-for-differentiated-thyroid-cancer
#12
Massimo Giusti, Miranda Mittica, Paola Comite, Claudia Campana, Stefano Gay, Michele Mussap
PURPOSE: In recent years, anti-Mullerian hormone (AMH) has been considered a reliable index of ovarian reserve. There are few data on AMH values in thyroid cancer. The aim of this study was to evaluate AMH levels in pre-menopausal women with a history of low-risk thyroid cancer. METHODS: Thirty-four women (aged 40.7 ± 6.7 years) were studied 7.1 ± 0.9 years after surgery and at least one RAI treatment. A group of 23 thyroid cancer women (41.6 ± 7...
January 4, 2018: Endocrine
https://www.readbyqxmd.com/read/29288262/rate-or-rhythm-control-of-atrial-fibrillation-pearls-for-the-internist
#13
Weiting Huang, Felix Yj Keng, Chi Keong Ching
Atrial fibrillation is an epidemic in Asia that is increasingly prevalent. Apart from stroke risk stratification and management of anticoagulation, physicians managing this group of patients also need to determine an optimal strategy in terms of rate or rhythm control. With new techniques of catheter ablation to maintain patients in sinus rhythm, patients with atrial fibrillation now have more options for treatment, on top of pharmacological methods. This paper aims to review the current evidence for rate and rhythm control in both general patients and subgroups of interest commonly encountered in clinical practices such as obesity, heart failure and thyroid disease...
November 2017: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/29262462/-progress-in-diagnosis-and-treatment-of-radioactive-iodine-refractory-differentiated-thyroid-carcinoma
#14
Z Zhao, G H Shen, Y H Li, K Zhou, H W Cai
The radioactive iodine-refractory differentiated thyroid carcinoma (RIR-DTC) is a complex process that involves multiple genetic changes and multiple signaling pathways.Radionuclide imaging, genomics and proteomics are effective to clarify the mechanism and helpful in clinical diagnosis and therapy.The treatment of RIR-DTC includes the removal of distant metastases, drug therapy, external radiotherapy and radiofrequency ablation.This review mainly focuses on the pathogenesis, diagnosis and treatment of RIR-DTC...
December 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/29242723/spect-ct-in-the-treatment-of-differentiated-thyroid-cancer
#15
REVIEW
Sang-Woo Lee
Single-photon emission computed tomography with integrated computed tomography (SPECT/CT) systems has been applied in a wide range of clinical circumstances, and differentiated thyroid cancer (DTC) is one of the most important indications of SPECT/CT imaging. In the treatment of DTC, SPECT/CT images have been reported to have many advantages over conventional planar whole-body scintigraphy based on its precise localization and characterization of abnormal foci of radioactive iodine (RAI) accumulation, influencing the staging, risk stratification, and clinical management as well as reader confidence...
December 2017: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29238849/video-assisted-thyroidectomy-for-papillary-thyroid-carcinoma-oncologic-outcome-in-patients-with-follow-up%C3%A2-%C3%A2-%C3%A2-10-years
#16
Rocco Bellantone, Marco Raffaelli, Carmela De Crea, Luca Sessa, Emanuela Traini, Pietro Princi, Celestino Pio Lombardi
BACKGROUND: Video-assisted thyroidectomy (VAT) arisen as a valid treatment for selected patients with papillary thyroid carcinoma (PTC), but no data concerning long-term oncologic outcome are available. The primary aim of the study was to evaluate the oncologic outcome of patients who underwent VAT for PTC with a follow-up ≥ 10 years. METHODS: The medical charts of all the patients who successfully underwent VAT for PTC were reviewed. The patients with a minimum follow-up period of 120-months were included...
December 13, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29230715/chronic-lymphocytic-thyroiditis-clt-has-a-positive-prognostic-value-in-papillary-thyroid-cancer-ptc-patients-the-potential-key-role-of-foxp3-%C3%A2-t-lymphocytes
#17
T Pilli, P Toti, R Occhini, M G Castagna, S Cantara, M Caselli, S Cardinale, L Barbagli, F Pacini
BACKGROUND: An impact of chronic lymphocytic thyroiditis (CLT) on papillary thyroid cancer (PTC) outcome has long been advocated but it is still controversial. PURPOSE: The aim of this study was to evaluate the prognostic value of CLT in a retrospective cohort of PTC patients and to characterize the lymphocytic subpopulations and infiltrate (LI). MATERIALS AND METHODS: We assessed 375 PTC patients, aged 45.2 ± 16.4 years, and treated with thyroidectomy and radioiodine remnant ablation, with a mean follow-up of 6...
December 11, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29228620/unfavorable-efficacy-to-131i-ablation-in-brafv600e-mutant-papillary-thyroid-carcinoma-with-positive-tgab
#18
Na Zhang, Jun Liang, Yan-Song Lin
The BRAFV600E mutation has shown a close relationship of aggressiveness in papillary thyroid carcinoma (PTC), while it remains unclear about its influence on the therapeutic response. As a common clinicopathologic risk factor, thyroglobulin antibody (TgAb) may have a correlation of prognosis in PTC. The objective was to investigate the relationship between BRAFV600E mutation and TgAb, and their combined effect on efficacy to radioiodine remnant ablation (RRA). This was a retrospective study including 298 PTC patients and they were divided into four groups according to the combined status...
November 14, 2017: Oncotarget
https://www.readbyqxmd.com/read/29224107/sex-dependent-role-of-estrogen-sulfotransferase-and-steroid-sulfatase-in-metabolic-homeostasis
#19
Wojciech G Garbacz, Mengxi Jiang, Wen Xie
Sulfonation and desulfation are two opposing processes that represent an important layer of regulation of estrogenic activity via ligand supplies. Enzymatic activities of families of enzymes, known as sulfotransferases and sulfatases, lead to structural and functional changes of the steroids, thyroids, xenobiotics, and neurotransmitters. Estrogen sulfotransferase (EST) and steroid sulfatase (STS) represent negative and positive regulation of the estrogen activity, respectively. This is because EST-mediated sulfation deactivates estrogens, whereas STS-mediated desulfation converts the inactive estrogen sulfates to active estrogens...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29214321/hemithyroidectomy-for-low-risk-follicular-carcinoma-of-thyroid-results-from-a-regional-hospital
#20
Tam-Lin Chow, Susanna Wai-Yin Tam, Chi-Yee Choi, Wilson Wai-Yin Kwan
INTRODUCTION: Excellent outcome after conservative thyroid surgery for low-risk follicular thyroid carcinoma (FTC) has been reported from highly specialised centres. However, it is uncertain whether similar treatment results can be achieved in low-volume hospitals. METHODS: At our institution, 49 patients with FTC were treated during 1991-2014. Patients with minimally invasive FTC (MIFTC) were usually treated with hemithyroidectomy. The demographic data, pathology, treatment modality and oncological outcomes of these patients were retrospectively evaluated...
December 7, 2017: Singapore Medical Journal
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