keyword
https://read.qxmd.com/read/38497388/radiofrequency-ablation-for-papillary-thyroid-microcarcinoma-close-to-the-thyroid-capsule-versus-far-from-the-thyroid-capsule-a-retrospective-study
#1
JOURNAL ARTICLE
Jieli Luo, Tianchen Hui, Peile Jin, Yang Sun, Yajun Chen, Zimei Lin, Pintong Huang
INTRODUCTION: The aim of this study was to evaluate the safety and efficacy of ultrasound-guided radiofrequency ablation (RFA) for the management of papillary thyroid microcarcinoma (PTMC) close to the thyroid capsule. MATERIAL AND METHODS: This was a retrospective study of 202 patients with PTMC who underwent RFA close to the thyroid capsule and 80 patients with PTMC who underwent RFA far from the thyroid capsule between June 2015 and December 2022. The follow-up time after RFA, change in size of tumour, location, thyroid function, the rates of PTMC disappearance, and complications were evaluated...
2024: Endokrynologia Polska
https://read.qxmd.com/read/38495395/an-unlikely-source-of-iodine-uptake-a-bronchogenic-cyst-masquerading-as-metastatic-thyroid-cancer
#2
Martha Dillon, Rachel Zielinski, Jennifer Worth, Melinda Sanders, Omar Ibrahim, Tarunya Vedere
Radioactive iodine therapy and posttreatment scanning are essential components of differentiated thyroid carcinoma treatment and detection of metastatic disease. False-positive results can be seen on an I-131 scan and are important for clinicians to be aware of. Here, we present a case of a 33-year-old female with follicular thyroid carcinoma who was noted to have an area of moderate uptake in the chest on a whole-body scan following remnant ablation with 30 mCi of I-131 (1.11GBq) concerning for a metastatic hilar lymph node...
March 2024: JCEM Case Rep
https://read.qxmd.com/read/38490098/uncommon-diagnosis-of-multinodular-goiter-isolated-extrapulmonary-manifestation-of-sarcoidosis-in-thyroid-gland-scientific-case-reports
#3
Marcel Neumann, Frank Meyer, Tatiana Oksentyuk Polyakova, Udo Barth, Dörthe Jechorek, Roland S Croner, Manuela Petersen
AIM: By means of the scientific description of two uncommon cases who underwent. surgical resection of multinodous goiter and following histopathological investigation revealing isolated extrapulmonary manifestation of sarcoidosis, this uncommon diagnosis including symptomatology, clinical findings, diagnostic and therapeutic management is to be illustrated. CASE DESCRIPTIONS: Diagnostics: Scintigraphy of the thyroid gland with a left-thyroid cold node; ultrasound-guided puncture (cytological investigation, non-suspicious)...
March 8, 2024: Pathology, Research and Practice
https://read.qxmd.com/read/38481630/retrospective-analysis-of-the-efficacy-and-safety-of-ultrasound-guided-radiofrequency-ablation-in-the-treatment-of-papillary-thyroid-microcarcinoma-a-follow-up-study-of-continuous-postoperative-surveillance-and-large-sample-data
#4
JOURNAL ARTICLE
Gongli Zhou, Xuefeng Zhang, Ke Xu, Beibei Zhang, Ruiqing Su, Tingting Cai, Wei Zhao, Feng Li
OBJECTIVE: To retrospectively evaluate the efficacy and safety of ultrasound-guided radiofrequency ablation (RFA) in the treatment of papillary thyroid microcarcinoma (PTMC) through a follow-up study of continuous postoperative surveillance and large-sample data. METHODS: The efficacy of ultrasound-guided RFA was evaluated by measuring the tumor volume reduction rate (VRR), tumor disappearance rate, and disease progression in 358 patients with low-risk unifocal PTMC who underwent ultrasound-guided RFA at Hangzhou Weja Hospital, while the safety was evaluated by measuring their complications...
2024: International Journal of Endocrinology
https://read.qxmd.com/read/38461585/highly-differentiated-follicular-carcinoma-of-the-ovary-with-omental-and-peritoneal-spread-in-a-22-year-old-girl-a-diagnostic-and-counseling-challenge
#5
Omar Hamdy, Abdullah N Nassar, Ahmed Hassan, Amany Hassan, Rehab T Eldesoky, Gehad Saleh
INTRODUCTION AND IMPORTANCE: Highly differentiated follicular carcinoma of the ovary (HDFCO) is a rare type of thyroid carcinoma originating from struma ovarii, consisting of benign-appearing thyroid follicles spread outside the ovarian tissue. CASE PRESENTATION: We present a 22-year-old girl who underwent left salpingo-oophorectomy, omental, and peritoneal biopsies for a complex left ovarian mass. Microscopic examination and Immunohistochemical staining led to the diagnosis of HDFCO with tumor deposits affecting the omental and peritoneal biopsies...
March 7, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38441255/accurate-preoperative-prediction-of-nodal-metastasis-in-papillary-thyroid-microcarcinoma-towards-optimal-management-of-patients
#6
JOURNAL ARTICLE
Si-Ying Lin, Meng-Yao Li, Chi-Peng Zhou, Wei Ao, Wen-Yu Huang, Si-Si Wang, Jia-Fan Yu, Zi-Han Tang, Amr H Abdelhamid Ahmed, Ting-Yi Wang, Zhi-Hong Wang, Surong Hua, Gregory W Randolph, Wen-Xin Zhao, Bo Wang
OBJECTIVE: To enhance the accuracy in predicting lymph node metastasis (LNM) preoperatively in patients with papillary thyroid microcarcinoma (PTMC), refining the "low-risk" classification for tailored treatment strategies. METHODS: This study involves the development and validation of a predictive model using a cohort of 1004 patients with PTMC undergoing thyroidectomy along with central neck dissection. The data was divided into a training cohort (n = 702) and a validation cohort (n = 302)...
March 5, 2024: Head & Neck
https://read.qxmd.com/read/38434608/primary-intrathoracic-ectopic-papillary-thyroid-carcinoma-presenting-with-thoracic-spine-metastasis-a-case-presentation-and-literature-review
#7
Rodhan Khthir, Nash B Binegar
Thyroid cancer in ectopic thyroid tissue is a very rare entity. We report a patient with papillary thyroid cancer arising from upper mediastinal ectopic thyroid tissue. The patient presented with thoracic spine metastasis with cord compression. The patient was a 67-year-old woman, who presented with upper back pain. Magnetic resonance imaging (MRI) showed suspected metastatic disease in the second and third thoracic vertebrae (T2 and T3). She underwent laminectomy and decompression surgery at the T1-T3 level...
March 2024: Curēus
https://read.qxmd.com/read/38430698/tshr-signaling-promotes-hippocampal-dependent-memory-formation-through-modulating-wnt5a-%C3%AE-catenin-mediated-neurogenesis
#8
JOURNAL ARTICLE
Yuchen Li, Sisi Luan, Cairong Ruan, Weihao Li, Xinyu Zhang, Zijing Ran, Wenkai Bi, Yuelin Tong, Ling Gao, Jiajun Zhao, Yuan Li, Zhao He
Subclinical hyperthyroidism is defined biochemically as a low or undetectable thyroid-stimulating hormone (TSH) with normal thyroid hormone levels. Low TSHR signaling is considered to associate with cognitive impairment. However, the underlying molecular mechanism by which TSHR signaling modulates memory is poorly understood. In this study, we found that Tshr-deficient in the hippocampal neurons impairs the learning and memory abilities of mice, accompanying by a decline in the number of newborn neurons. Notably, Tshr ablation in the hippocampus decreases the expression of Wnt5a, thereby inactivating the β-catenin signaling pathway to reduce the neurogenesis...
February 28, 2024: Biochemical and Biophysical Research Communications
https://read.qxmd.com/read/38424177/combined-clinical-variable-and-radiomics-of-post-treatment-total-body-scan-for-prediction-of-successful-i-131-ablation-in-low-risk-papillary-thyroid-carcinoma-patients
#9
JOURNAL ARTICLE
Maythinee Chantadisai, Jirarot Wongwijitsook, Napat Ritlumlert, Yothin Rakvongthai
To explore the feasibility of combined radiomics of post-treatment I-131 total body scan (TBS) and clinical parameter to predict successful ablation in low-risk papillary thyroid carcinoma (PTC) patients. Data of low-risk PTC patients who underwent total/near total thyroidectomy and I-131 ablation 30 mCi between April 2015 and July 2021 were retrospectively reviewed. The clinical factors studied included age, sex, and pre-ablative serum thyroglobulin (Tg). Radiomic features were extracted via PyRadiomics, and radiomic feature selection was performed...
February 29, 2024: Scientific Reports
https://read.qxmd.com/read/38421515/nuclear-medicine-practice-in-japan-a-report-of-the-ninth-nationwide-survey-in-2022
#10
JOURNAL ARTICLE
Atsutaka Okizaki, Yoshihiro Nishiyama, Yoshitaka Inui, Hideki Otsuka, Kentaro Takanami, Masatoyo Nakajo, Koya Nakatani, Munenobu Nogami, Kenji Hirata, Yukito Maeda, Mana Yoshimura, Hiroshi Wakabayashi
Subcommittee on Survey of Nuclear Medicine Practice in Japan has performed a nationwide survey of nuclear medicine practice every 5 years since 1982 to survey contemporary nuclear medicine practice and its changes over the years. The subcommittee sent questionnaires, including the number and category of examinations as well as the kind of the radiopharmaceuticals during the 30 days of June 2022 to all nuclear medicine institutes in Japan. The total numbers of them for the year 2022 were estimated depends on the 1-month data...
February 29, 2024: Annals of Nuclear Medicine
https://read.qxmd.com/read/38418029/srt-swin-residual-transformer-for-benign-and-malignant-nodules-classification-in-thyroid-ultrasound-images
#11
JOURNAL ARTICLE
Long Huang, Yanran Xu, Shuhuan Wang, Liang Sang, He Ma
With the advancement of deep learning technology, computer-aided diagnosis (CAD) is playing an increasing role in the field of medical diagnosis. In particular, the emergence of Transformer-based models has led to a wider application of computer vision technology in the field of medical image processing. In the diagnosis of thyroid diseases, the diagnosis of benign and malignant thyroid nodules based on the TI-RADS classification is greatly influenced by the subjective judgment of ultrasonographers, and at the same time, it also brings an extremely heavy workload to ultrasonographers...
February 2024: Medical Engineering & Physics
https://read.qxmd.com/read/38413114/comparative-efficacy-and-safety-of-radiofrequency-ablation-and-microwave-ablation-in-the-treatment-of-benign-thyroid-nodules-a-systematic-review-and-meta-analysis
#12
JOURNAL ARTICLE
Hendra Zufry, Timotius Ivan Hariyanto
OBJECTIVE: The current body of evidence lacks clarity regarding the comparative efficacy and safety of radiofrequency ablation (RFA) and microwave ablation (MWA) as minimally invasive treatments for benign thyroid nodules. The primary objective of this study is to clarify these concerns. MATERIALS AND METHODS: A comprehensive search was conducted using the Cochrane Library, Scopus, Europe PMC, and Medline databases until October 10th, 2023, using a combination of relevant keywords...
March 2024: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://read.qxmd.com/read/38412750/perimenopausal-abnormal-uterine-bleeding
#13
REVIEW
Eva Dreisler, Christian Seerup Frandsen, Lian Ulrich
Abnormal uterine bleeding is a frequent symptom in the perimenopause. Causes are numerous, ranging from physiological reactions due to decreasing/unstable ovarian function to premalignant and malignant conditions. Benign findings such as endometrial polyps and myomas increase with age, leading to more abnormal uterine bleeding in the perimenopause. Cervical and vaginal causes of abnormal uterine bleeding should be excluded by speculum examination. Sexually transmitted diseases or pregnancy should be ruled out...
February 22, 2024: Maturitas
https://read.qxmd.com/read/38408985/protect-the-recurrent-laryngeal-nerves-in-us-guided-microwave-ablation-of-thyroid-nodules-at-zuckerkandl-tubercle-a-pilot-study
#14
JOURNAL ARTICLE
Ziyue Hu, Lu Wang, Man Lu, Wei Yang, Xiaobo Wu, Jinshun Xu, Min Zhuang, Shishi Wang
BACKGROUND: To evaluate the safety and efficacy of US-guided microwave ablation in patients with thyroid nodules at Zuckerkandl tubercle. METHODS: 103 consecutive patients with thyroid nodules at Zuckerkandl tubercle (ZTTN) were enrolled in this study from November 2017 to August 2021. Prior to the surgery or US-guided microwave ablation (MWA), preoperative ultrasound visualization of the recurrent laryngeal nerve (RLN) and ZTTN was performed, the size and the position relationship between them were observed...
February 26, 2024: BMC Cancer
https://read.qxmd.com/read/38397952/minimal-extrathyroid-extension-mete-as-the-only-risk-factor-in-patients-with-papillary-thyroid-carcinoma-pc-its-clinical-impact-on-recurrence-and-outcome-during-long-term-follow-up
#15
JOURNAL ARTICLE
Andrea Marongiu, Susanna Nuvoli, Andrea De Vito, Sonia Vargiu, Angela Spanu, Giuseppe Madeddu
Minimal extrathyroid extension (mETE) effect on papillary thyroid carcinoma (PC) prognosis is still debated even more so now that this factor has been removed in the 8th AJCC Edition, supporting the hypothesis that mETE is not associated with aggressive tumors. We retrospectively enrolled 91 PC patients (Group 1) submitted to total thyroidectomy and radioiodine ablation. At the time of the primary tumor surgery, mETE was ascertained in all patients with no other risk factors, such as multifocality, vascular invasion, neck and distant metastases, and aggressive histological variants...
February 2, 2024: Biomedicines
https://read.qxmd.com/read/38394504/an-unusual-evolution-of-thyroid-function-after-therapeutic-plasma-exchange-in-graves-disease-with-cholestatic-jaundice-a-case-report
#16
JOURNAL ARTICLE
Yamei Jin, Xiaohong Feng, Haixiang Ni
RATIONALE: Methimazole (MMI) is the first-line agent in the treatment of hyperthyroidism. However, rare but severe cholestatic jaundice may occur. Therapeutic plasma exchange (TPE) may provide an alternative treatment for such patients and they received thyroidectomy/radioactive iodine ablation or continued oral anti hyperthyroidism medication immediately after TPE session in the reported literatures. The case reported here is, to our knowledge, the first to describe the long interval between anti hyperthyroidism therapy and TPE in such patients...
February 23, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38394093/sublethal-thermal-stress-promotes-migration-and-invasion-of-thyroid-cancer-cells
#17
JOURNAL ARTICLE
Chi-Yu Kuo, Chung-Hsin Tsai, Jun Kui Wu, Shih-Ping Cheng
OBJECTIVE: Radiofrequency ablation is a viable option in the treatment of benign thyroid nodules. Some reports suggest that thermal ablation may also be safe for the management of low-risk thyroid cancer. In this study, we applied transient heat treatment to thyroid cancer cells to mimic clinical scenarios in which insufficient ablation leads to incomplete eradication of thyroid cancer. METHODS: Differentiated thyroid cancer cell lines B-CPAP, TPC-1, and FTC-133 were subjected to heat treatment at different temperatures for 10 min...
2024: PloS One
https://read.qxmd.com/read/38392064/papillary-thyroid-microcarcinoma-differences-between-lesions-in-incidental-and-nonincidental-settings-considerations-on-these-clinical-entities-and-personal-experience
#18
JOURNAL ARTICLE
Giorgio Lucandri, Giulia Fiori, Francesco Falbo, Vito Pende, Massimo Farina, Paolo Mazzocchi, Assunta Santonati, Daniela Bosco, Antonio Spada, Emanuele Santoro
Papillary thyroid microcarcinoma (PTMC) represents 35-40% of all papillary cancers; it is defined as a nodule ≤ 10 mm at the time of histological diagnosis. The clinical significance of PTMC is still controversial, and it may be discovered in two settings: incidental PTMC (iPTMC), in which it is identified postoperatively upon histological examination of thyroid specimens following thyroid surgery for benign disease, and nonincidental PTMC (niPTMC), in which it is diagnosed before surgery. While iPTMC appears to be related to mild behavior and favorable clinical outcomes, niPTMC may exhibit markers of aggressiveness...
February 6, 2024: Current Oncology
https://read.qxmd.com/read/38376867/comparison-of-safety-efficacy-and-patient-satisfaction-with-thermal-ablation-versus-endoscopic-thyroidectomy-for-benign-thyroid-nodules-in-a-propensity-matched-cohort
#19
JOURNAL ARTICLE
Ting-Chun Kuo, Kuen-Yuan Chen, Chieh-Wen Lai, Yi-Chia Wang, Ming-Tsan Lin, Chin-Hao Chang, Ming-Hsun Wu
BACKGROUND: Thyroid nodules (TNs) often require intervention due to symptomatic or cosmetic concerns. Radiofrequency ablation (RFA) has shown promise as a treatment option, offering potential advantages without neck scars. Recently, the scarless treatment alternative of transoral endoscopic thyroidectomy vestibular approach (TOETVA) has emerged. When surgery can be performed in a scarless manner, it remains unclear whether ablation is still the preferred treatment choice. This study aims to compare the safety, efficacy, and patient satisfaction of RFA and TOETVA...
February 19, 2024: International Journal of Surgery
https://read.qxmd.com/read/38362180/the-safety-and-efficacy-of-radiofrequency-ablation-in-benign-pediatric-thyroid-disease-in-the-us-an-initial-case-series
#20
JOURNAL ARTICLE
Grace S Kim, Hilary Seeley, Julia Noel, Iram Ahmad, Kara Meister
OBJECTIVE: To evaluate the efficacy and safety of radiofrequency ablation (RFA) for benign nonfunctional thyroid nodules or functional lingual thyroid gland in a pediatric population. METHODS: Four pediatric patients (four female; mean age 13.50 ± 4.04, range 8-17 years) with either benign thyroid nodules or mildly obstructive lingual thyroid glands were treated with RFA from 2020 to 2021 were evaluated. The inclusion criteria for RFA therapy were (i) age < 18 years; (ii) benign cytopathological results on ultrasound guided fine needle aspiration; (iii) pressure or pain symptoms caused by the thyroid nodules; (iv) dysphagia or obstruction caused by the lingual thyroid tissue; (v) follow up for >6 months with otolaryngology or endocrinology...
February 2024: Laryngoscope Investigative Otolaryngology
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