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https://www.readbyqxmd.com/read/29025123/comparative-epidemiology-of-clostridium-difficile-infection-england-and-the-usa
#1
Alice King, Benjamin H Mullish, Horace R T Williams, Paul Aylin
Objective: To examine whether there is an epidemiological difference between Clostridium difficile infection (CDI) inpatient populations in England and the United States. Design: A cross-sectional study. Setting: National administrative inpatient discharge data from England (Hospital Episode Statistics) and the USA (National Inpatient Sample) in 2012. Participants: De-identifiable non-obstetric inpatient discharges from the national datasets were used to estimate national CDI incidence in the United States and England using ICD9-CM(008...
September 11, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28992379/association-between-anti-citrullinated-fibrinogen-antibodies-and-coronary-artery-disease-in-rheumatoid-arthritis
#2
Boris P Hejblum, Jing Cui, Lauren J Lahey, Andrew Cagan, Jeffrey A Sparks, Jeremy Sokolove, Tianxi Cai, Katherine P Liao
OBJECTIVE: Antibodies against citrullinated fibrinogen (anti-cit-fibrinogen) have been implicated in both rheumatoid arthritis (RA) and cardiovascular (CV) risk in RA. The objective of this study was to examine the association between anti-cit-fibrinogens and coronary artery disease (CAD) outcomes. METHODS: We performed the study in an RA cohort based in a large academic institution linked with electronic medical record data (EMR) containing data on CAD outcomes from medical record review...
October 9, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28989837/trends-costs-and-complications-of-anterior-cervical-discectomy-and-fusion-with-and-without-bone-morphogenetic-protein-in-the-united-states-medicare-population
#3
REVIEW
Elizabeth L Lord, Jeremiah R Cohen, Zorica Buser, Hans-Joerg Meisel, Darrel S Brodke, S Tim Yoon, Jim A Youssef, Jeffrey C Wang, Jong-Beom Park
STUDY DESIGN: Retrospective database review. OBJECTIVES: After the Food and Drug Administration approved bone morphogenetic protein-2 (BMP) in 2002, BMP was used off-label in the cervical spine to increase bone growth and bony fusion. Since then, concerns have been raised regarding complication rates and safety. This study was conducted to examine the use of BMP in anterior cervical discectomy and fusion (ACDF) in the Medicare population and to determine risk of complications and associated costs within 90 days of surgery...
October 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28914274/influenza-season-hospitalization-trends-in-israel-a-multi-year-comparative-analysis-2005-2006-through-2012-2013
#4
Aharona Glatman-Freedman, Zalman Kaufman, Yaniv Stein, Hanna Sefty, Hilla Zadka, Barak Gordon, Jill Meron, Ethel-Sherry Gordon, Rita Dichtiar, Ziona Haklai, Arnon Afek, Tamy Shohat
BACKGROUND: Influenza-related morbidity impacts healthcare systems, including hospitals. OBJECTIVE: To obtain a quantitative assessment of hospitalization burden in pediatric and internal medicine departments during influenza seasons compared with the summer months in Israel. METHODS: Data on pediatric and internal medicine hospitalized patients in general hospitals in Israel during the influenza seasons between 2005 and 2013 were analyzed for rate of hospitalizations, rate of hospitalization days, hospital length of stay (LOS), and bed occupancy and compared with the summer months...
September 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/28830083/metoprolol-increases-uric-acid-and-risk-of-gout-in-african-americans-with-chronic-kidney-disease-attributed-to-hypertension
#5
Stephen P Juraschek, Lawrence J Appel, Edgar R Miller
BACKGROUND: There is little evidence guiding selection of nondiuretic, antihypertensive agents with a goal of lowering uric acid (SUA) and minimizing gout risk. METHODS: In the African American Study of Kidney Disease and Hypertension (AASK) trial, African Americans with chronic kidney disease were randomly assigned to metoprolol (a beta-blocker), ramipril (an angiotensin-converting enzyme inhibitors [ACEi]), or amlodipine (a dihydropyridine calcium-channel blocker)...
September 1, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28814278/epidemiology-and-outcomes-of-endophthalmitis-in-chronic-dialysis-patients-a-13-year-experience-in-a-tertiary-referral-center-in-taiwan
#6
George Kuo, Yueh-An Lu, Wei-Chiao Sun, Chao-Yu Chen, Huang-Kai Kao, YuJr Lin, Chia-Hui Lee, Cheng-Chieh Hung, Ya-Chung Tian, Hsiang-Hao Hsu
BACKGROUND: Endophthalmitis is a severe eye infection leading to disabling outcome. Because there were only a few case report illustrating endophthalmitis in chronic dialysis patient, we would like to investigate the epidemiology and clinical features of endophthalmitis in chronic dialysis patient in a tertiary referral center. METHODS: We searched the health information system in the study hospital with ICD9 encoding endophthalmitis during Jan. 2002 to Dec. 2015...
August 16, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28813166/are-inner-city-children-with-asthma-receiving-specialty-care-as-recommended-in-national-asthma-guidelines
#7
Karen L Warman, Ellen J Silver
OBJECTIVE: To examine whether children with asthma in an urban health care network are receiving asthma specialty care, and which factors, if any, are associated with the receipt of this care, including child's racial/ethnic group, age, socio-economic status (SES), insurance, and/or acute care utilization. METHODS: This study is a retrospective cohort study of children aged 7-17 years who received primary care at an urban medical center in 2012 and had a primary or secondary ICD9 code for asthma...
August 16, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28796094/patulous-eustachian-tube-dysfunction-patient-demographics-and-comorbidities
#8
Bryan K Ward, Yehia Ashry, Dennis S Poe
OBJECTIVE: The objective is to describe a large cohort of patients presenting with patulous Eustachian tube (pET) dysfunction. STUDY DESIGN: Retrospective patient series. SETTING: Tertiary referral center. PATIENTS: All outpatient visits (2004-2016) that were assigned ICD9 code (381.7-Patulous Eustachian tube) were screened. Only patients with observed tympanic membrane movements during ipsilateral nasal breathing or acoustic reflex decay testing demonstrating transmitted nasal breathing were included (n = 190, n = 239 ears)...
October 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28725879/using-closure-tables-to-enable-cross-querying-of-ontologies-in-database-driven-applications
#9
Daniel R Harris, Darren W Henderson, Jeffery C Talbert
We demonstrate that closure tables are an effective data structure for developing database-driven applications that query biomedical ontologies and that require cross-querying between multiple ontologies. A closure table stores all available paths within a tree, even those without a direct parent-child relationship; additionally, a node can have multiple ancestors which gives the foundation for supporting linkages between controlled ontologies. We augment the meta-data structure of the ICD9 and ICD10 ontologies included in i2b2, an open source query tool for identifying patient cohorts, to utilize a closure table...
February 2017: IEEE-EMBS International Conference on Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28715497/risk-of-gestational-hypertension-preeclampsia-in-women-with-preceding-endometriosis-a-nationwide-population-based-study
#10
Mei-Lien Pan, Li-Ru Chen, Hsiao-Mei Tsao, Kuo-Hu Chen
OBJECTIVE: To investigate the association between preceding endometriosis and gestational hypertension-preeclampsia (GH-PE). METHODS: In this nationwide population-based longitudinal study, data from 1998-2012 Taiwan National Health Insurance Research Database were used. We used ICD9-CM codes 617.X and 642.X respectively for the diagnoses of endometriosis and GH-PE, which were further confirmed by examining medical records of surgeries, blood pressure and urine protein to ensure the accuracy of the diagnoses...
2017: PloS One
https://www.readbyqxmd.com/read/28713293/predicting-future-high-cost-schizophrenia-patients-using-high-dimensional-administrative-data
#11
Yajuan Wang, Vijay Iyengar, Jianying Hu, David Kho, Erin Falconer, John P Docherty, Gigi Y Yuen
BACKGROUND: The burden of serious and persistent mental illness such as schizophrenia is substantial and requires health-care organizations to have adequate risk adjustment models to effectively allocate their resources to managing patients who are at the greatest risk. Currently available models underestimate health-care costs for those with mental or behavioral health conditions. OBJECTIVES: The study aimed to develop and evaluate predictive models for identification of future high-cost schizophrenia patients using advanced supervised machine learning methods...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28682317/a-management-strategy-that-reduces-nicu-admissions-and-decreases-charges-from-the-front-line-of-the-neonatal-abstinence-syndrome-epidemic
#12
S Loudin, J Werthammer, L Prunty, S Murray, J I Shapiro, T H Davies
OBJECTIVE: The purpose of this study was to test a specialized needs-based management model for a high volume of babies born with neonatal abstinence syndrome (NAS) while controlling costs and reducing neonatal intensive care unit (NICU) bed usage. STUDY DESIGN: Data were analyzed from inborn neonates >35 weeks' gestational age with the diagnosis of NAS (ICD9-CM 779.5), requiring pharmacologic treatment and discharged from 2010 through 2015. Significance was determined using Kruskal-Wallis and Mann-Whitney as well as χ(2) for trend...
October 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28664428/routine-versus-selective-upper-gastrointestinal-contrast-series-after-omental-patch-repair-for-gastric-or-duodenal-perforation
#13
Stephenie Poris, Andrew Fontaine, Julie Glener, Stacey Kubovec, Paula Veldhuis, Yuan Du, Julie Pepe, Steve Eubanks
BACKGROUND: There are no guidelines on the routine or selective use of contrast upper gastrointestinal series (UGI) after omental patch repair (OPR) of a gastric (GP) or duodenal perforation (DP). This study aims to elucidate whether the use of selective versus routine contrast study will lead to worse clinical outcomes. METHODS: A retrospective analysis of 115 (n = 115) patients with OPR of GP or DP was performed. Data were obtained from seven Florida Hospital campuses...
June 29, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28664412/early-use-of-ceftaroline-fosamil-in-the-united-states-veterans-health-care-system
#14
Rachel S Britt, Kirk E Evoy, Grace C Lee, Kelly R Reveles, Kimberly M Sorensen, Xavier Jones, Mary Bollinger, Christopher R Frei
BACKGROUND: Ceftaroline fosamil is US Food and Drug Administration-approved for acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia, but it is not known how ceftaroline is being used in real-world settings or how adverse effects (AEs) and mortality compare to clinical trials. OBJECTIVE: This study describes ceftaroline use, AEs, and mortality in US Veterans Health Administration (VHA) hospital patients. METHODS: This phase IV, population-based, epidemiologic study analyzed patients ≥18 years old who received one or more ceftaroline doses within 14 days of admission to 69 VHA hospitals in 41 US states/territories from 1 October 2010 to 30 September 2014...
August 2017: Drugs
https://www.readbyqxmd.com/read/28651554/validation-of-an-international-classification-of-disease-ninth-revision-coding-algorithm-to-identify-decompressive-craniectomy-for-stroke
#15
Hormuzdiyar H Dasenbrock, David J Cote, Yuri Pompeu, Viren S Vasudeva, Timothy R Smith, William B Gormley
BACKGROUND: Although International Classification of Disease, Ninth Revision, Clinical Modification (ICD9-CM) coding is the basis of administrative claims data, no study has validated an ICD9-CM algorithm to identify patients undergoing decompressive craniectomy for space-occupying supratentorial infarction. METHODS: Patients who underwent decompressive craniectomy for stroke at our institution were retrospectively identified and their associated ICD9-CM codes were extracted from billing data...
June 26, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28641361/maternal-alcohol-use-disorder-and-risk-of-child-contact-with-the-justice-system-in-western-australia-a-population-cohort-record-linkage-study
#16
Katherine Hafekost, David Lawrence, Colleen O'Leary, Carol Bower, James Semmens, Stephen R Zubrick
BACKGROUND: Early contact with the justice system is associated with a multitude of negative outcomes across the life course. This includes an increased risk of ongoing justice contact, social disadvantage and marginalization, and mental health and substance use issues. Children whose mothers have an alcohol use disorder may be at risk of early justice system contact, and we sought to quantify this relationship in a Western Australian cohort. METHODS: This population cohort study made use of linked administrative data...
August 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28583812/cost-of-bariatric-surgery-and-factors-associated-with-increased-cost-an-analysis-of-national-inpatient-sample
#17
Zhamak Khorgami, Ali Aminian, Saeed Shoar, Amin Andalib, Alan A Saber, Philip R Schauer, Stacy A Brethauer, Guido M Sclabas
BACKGROUND: In the current healthcare environment, bariatric surgery centers need to be cost-effective while maintaining quality. OBJECTIVE: The aim of this study was to evaluate national cost of bariatric surgery to identify the factors associated with a higher cost. SETTING: A retrospective analysis of 2012-2013 Healthcare Cost and Utilization Project - Nationwide Inpatient Sample (HCUP-NIS). METHOD: We included all patients with a diagnosis of morbid obesity (ICD9 278...
August 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28529665/slipped-capital-femoral-epiphysis-a-spectrum-of-surgical-care-and-changes-over-time
#18
R T Loder
PURPOSE: To survey the spectrum of surgical care in children with slipped capital femoral epiphysis (SCFE). This information is valuable in counselling the patient about the future treatment course. METHODS: Data for this study were obtained from the Pediatric Hospital Information System (PHIS) between 2004 and 2015. For all patients with an ICD9 diagnosis of 732.2, gender, ethnicity, hospital, medical record number, date of birth/admission/discharge, type of admission, length of stay, disposition and treatment(s) rendered were collected...
April 2017: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/28488237/perioperative-bleeding-and-thrombotic-risks-in-patients-with-von-willebrand-disease
#19
Nathaniel R Smilowitz, Navdeep Gupta, Yu Guo, Sripal Bangalore, Jeffrey S Berger
Von Willebrand disease (VWD) is an inherited bleeding disorder that often manifests clinically with hemorrhage after invasive procedures. We investigated the association between a diagnosis of VWD and bleeding and thrombotic outcomes following major non-cardiac surgery in a large national database from the United States. Patients age ≥45 years requiring major non-cardiac surgery were identified from Healthcare Cost and Utilization Project's National Inpatient Sample data. Von Willebrand disease, perioperative major adverse cardiovascular events (MACE), thrombotic events, and hemorrhage were defined by ICD9 diagnosis codes...
July 2017: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/28469696/hospital-days-attributable-to-immune-reconstitution-inflammatory-syndrome-in-persons-living-with-hiv-before-and-after-the-2012-dhhs-hiv-guidelines
#20
Peter Liu, Rebecca Dillingham, Kathleen McManus
BACKGROUND: Immune reconstitution inflammatory syndrome (IRIS) can manifest with initiation or reintroduction of antiretroviral therapy (ART) in persons living with HIV (PLWH). In 2012, updated United States treatment guidelines recommended initiation of ART for all PLWH regardless of CD4 count. The objectives of this study were to quantify hospital usage attributable to IRIS and assess the reasons for hospitalization in PLWH before and after the guideline update. METHODS: Subjects were PLWH between 18-89 years of age who were hospitalized between November 1, 2009 and July 31, 2014...
2017: AIDS Research and Therapy
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