keyword
https://read.qxmd.com/read/38365301/development-and-validation-of-new-multimorbidity-weighted-index-for-icd-10-coded-electronic-health-record-and-claims-data-an-observational-study
#21
JOURNAL ARTICLE
Melissa Y Wei, Aleda M Leis, Arseniy Vasilyev, Ashley J Kang
OBJECTIVE: Map multimorbidity-weighted index (MWI) conditions to International Classification of Diseases, 10th Revision (ICD-10), expand the conditions and codes to develop a new ICD-10-coded MWI (MWI-ICD10) and updated MWI-ICD9, and assess their consistency. DESIGN: Population-based retrospective cohort. SETTING: Large medical centre between 2013 and 2017. PARTICIPANTS: Adults ≥18 years old with encounters in each of 4 years (2013, 2014, 2016, 2017)...
February 15, 2024: BMJ Open
https://read.qxmd.com/read/38361485/updated-eurocat-guidelines-for-classification-of-cases-with-congenital-anomalies
#22
JOURNAL ARTICLE
Jorieke E H Bergman, Annie Perraud, Ingeborg Barišić, Agnieszka Kinsner-Ovaskainen, Joan K Morris, David Tucker, Diana Wellesley, Ester Garne
BACKGROUND: Precise and correct classification of congenital anomalies is important in epidemiological studies, not only to classify according to etiology but also to group similar congenital anomalies together, to create homogeneous subgroups for surveillance and research. This paper presents the updated EUROCAT (European surveillance of congenital anomalies) subgroups of congenital anomalies and the updated multiple congenital anomaly (MCA) algorithm and provides the underlying arguments for the revisions...
February 2024: Birth Defects Research
https://read.qxmd.com/read/38360600/repeated-hospital-admission-for-intentional-poisonings-among-older-adults-a-swedish-national-register-based-study
#23
JOURNAL ARTICLE
L Laflamme, E Lindholm, Jette Möller
BACKGROUND: Poisoning injuries is an increasing concern among older people, and so is the repetition of intentional poisonings. To date, few studies have documented the pattern and individual risk factors for repeated poisonings. This national study aims to shed light on the burden, pattern, and health-related risk factors of repeated intentional poisoning leading to hospitalization or death among older Swedish adults (50 years and older), with a focus on the year following a first event...
February 15, 2024: BMC Geriatrics
https://read.qxmd.com/read/38359475/racial-disparities-in-hospitalization-characteristics-among-native-hawaiians-pacific-islanders-and-asian-american-subgroups-with-parkinson-s-disease
#24
JOURNAL ARTICLE
Michiko Kimura Bruno, Masako Matsunaga, Emma Krening, Kazuma Nakagawa, John J Chen, Todd Seto, Fay Gao, Caroline Tanner, G Webster Ross
BACKGROUND: Differences among Native Hawaiians/Pacific Islanders (NHPI) and Asian American (AA) subgroups have not been adequately studied in Parkinson's disease (PD). OBJECTIVE: To determine differences in demographics, comorbidities, and healthcare utilization among NHPI, AA subgroups, and White hospitalized PD patients. METHODS: We conducted a retrospective cross-sectional analysis of Hawai'is statewide registry (2016-2020). Patients with PD were identified using ICD10 code G20 and categorized as White, Japanese, Filipino, Chinese, NHPI, or Other...
February 2, 2024: Parkinsonism & related Disorders
https://read.qxmd.com/read/38357394/a-wide-landscape-of-morbidity-and-mortality-risk-associated-with-marital-status-in-0-5-million-chinese-men-and-women-a-prospective-cohort-study
#25
JOURNAL ARTICLE
Meng Xiao, Aolin Li, Yueqing Wang, Canqing Yu, Yuanjie Pang, Pei Pei, Ling Yang, Yiping Chen, Huaidong Du, Dan Schmidt, Daniel Avery, Qiang Sun, Junshi Chen, Zhengming Chen, Liming Li, Jun Lv, Dianjianyi Sun
BACKGROUND: A comprehensive depiction of long-term health impacts of marital status is lacking. METHODS: Sex-stratified phenome-wide association analyses (PheWAS) of marital status (living with vs. without a spouse) were performed using baseline (2004-2008) and follow-up information (ICD10-coded events till Dec 31, 2017) from the China Kadoorie Biobank (CKB). We estimated adjusted hazard ratios (aHRs) to evaluate the associations of marital status with morbidity risks of phenome-wide significant diseases or sex-specific top-10 death causes in China documented in 2017...
January 2024: The Lancet Regional Health. Western Pacific
https://read.qxmd.com/read/38352405/a-vagal-influence-on-schizophrenia-a-nationwide-retrospective-cohort-of-vagotomized-individuals
#26
Cornelia F Richter, Karolina P Skibicka, Urs Meyer, Sabine Rohrmann, Jean-Philippe Krieger
Emerging preclinical evidence suggests that vagal signals contribute to the development of schizophrenia-related abnormalities in brain and behavior. Whether vagal communication in general, and its impairment in particular, is a risk factor for schizophrenia in humans remains, however, unclear. Vagotomy, the surgical lesion of the vagus nerve, was routinely performed as a treatment for peptic ulcer before modern treatment options were available. Hence, the primary aim of this study was to investigate whether vagotomy modulates the subsequent risk of developing schizophrenia...
January 30, 2024: medRxiv
https://read.qxmd.com/read/38346485/short-term-impact-of-air-pollution-noise-and-temperature-on-emergency-hospital-admissions-in-madrid-spain-due-to-liver-and-gallbladder-diseases
#27
JOURNAL ARTICLE
J A López-Bueno, A Padrón-Monedero, J Díaz, M A Navas-Martín, C Linares
BACKGROUND: Very few epidemiological studies have explored the environmental and meteorological risk factors that influence liver diseases and gallbladder disorders, and no studies have addressed the specific case of Spain. METHODS: This is a retrospective ecological study conducted during 2013-2018. We analysed emergency admissions in the central area of the Region of Madrid for the following causes: Liver and gallbladder diseases (L&GB) (ICD-10: K70-K81); disorders of gallbladder (DGB) (ICD 10: K80-K81); liver disease (LD) (ICD 10: K70-K77); alcoholic liver disease (ALD) (ICD-10: K70); viral hepatitis (VH) (ICD10:B15-B19); and hepatic failure, not elsewhere classified (HFNS) (ICD-10: K72)...
February 10, 2024: Environmental Research
https://read.qxmd.com/read/38325557/superior-labrum-anterior-to-posterior-slap-repair-is-associated-with-increased-rate-of-subsequent-rotator-cuff-diagnoses-and-revision-surgery-a-propensity-matched-comparison
#28
JOURNAL ARTICLE
Laura J Linscheid, Sterling J DeShazo, Sabrina M Pescatore, Jeremy S Somerson
BACKGROUND: Surgical management of superior labrum anterior to posterior (SLAP) tears remains controversial. Current management utilizes 2 well-established procedures: biceps tenodesis and SLAP repair. This study evaluates the complications associated with arthroscopic SLAP repair versus an open or arthroscopic biceps tenodesis to further elucidate optimal surgical management. METHODS: In this retrospective cohort study, the TriNetX database was utilized to evaluate patients who underwent repair of SLAP lesions (ICD10:S43...
February 5, 2024: Journal of Shoulder and Elbow Surgery
https://read.qxmd.com/read/38276108/time-trend-analysis-of-comorbidities-in-ankylosing-spondylitis-a-population-based-study-from-53-142-hospitalizations-in-poland
#29
JOURNAL ARTICLE
Katarzyna Helon, Małgorzata Wisłowska, Krzysztof Kanecki, Paweł Goryński, Aneta Nitsch-Osuch, Krzysztof Bonek
BACKGROUND: (1) Influence of comorbidities on life expectancy and treatment outcomes is one of the main concerns of modern rheumatology, due to their rising prevalence and increasing impact on mortality and disability. The main objective of our study was to analyze the time trends and shifts in the comorbidity profile and mortality over 10 years in the Polish population with ankylosing spondylitis (AS). (2) Data from 2011-2020 years were acquired from the General Hospital Morbidity Study in the National Institute of Public Health-National Institute of Hygiene (NIH-PIB) as ICD-10 codes...
January 21, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38254127/the-15-year-national-trends-of-urinary-cancers-incidence-among-iranian-men-and-women-2005-2020
#30
JOURNAL ARTICLE
Amir-Hossein Mousavian, Gita Shafiee, Ali Sheidaei, Narges Zargar Balajam, Mehdi Ebrahimi, Fatemeh Khatami, Kimiya Gohari, Alisam Aryan, Ali Ghanbari-Motlagh, Afshin Ostovar, Seyed Mohammad Kazem Aghamir, Ramin Heshmat
BACKGROUND: Urinary tract cancers including bladder, kidney, ureter, and pelvis are a common malignancy worldwide with high mortality ratio. Aimed to investigate the prevalence of these cancers, we conducted this study. METHODS: In this study, all the information related to ICD10 codes, gender, age and province of residence of individuals were obtained from the data of Iran's cancer registry by the Ministry of Health, Medicine and Medical Education and demographic evidence for each sub-country from the reports of Statistics Center of Iran (SCI)...
January 22, 2024: International Journal for Equity in Health
https://read.qxmd.com/read/38242891/chek2-knockout-is-a-therapeutic-target-for-tp53-mutated-hepatocellular-carcinoma
#31
JOURNAL ARTICLE
Yuyan Chen, Zhengyi Zhu, Xingyu Wu, Hui Li, Wenxian Guan, Haozhen Ren
Currently, there is still a lack of novel and effective drug targets to improve the prognosis of hepatocellular carcinoma (HCC). Additionally, the role of CHEK2 in HCC has not been reported yet. The eQTLgen database and two HCC Genome-Wide Association Study (GWAS) datasets (ieu-b-4953, ICD10 C22.0) were used to find the drug target: CHEK2. Next, Colony, Edu, β-gal, and cell cycle analysis were facilitated to evaluate the role of CHEK2 knockout in HCC. In addition, Nultin-3 was added to evaluate the apoptosis of TP53-mutated HCC cells with CHEK2 knockout...
January 19, 2024: Cell Death Discovery
https://read.qxmd.com/read/38235170/types-predictors-and-consequences-of-medicines-related-problems-mrps-in-frail-older-adults-admitted-to-hospital-from-primary-care-a-retrospective-cohort-study
#32
JOURNAL ARTICLE
Rosetta Chinyere Ude-Okeleke, Zoe Aslanpour, Soraya Dhillon, Rachel Berry, Emma Bines, Nkiruka Umaru
INTRODUCTION: Medicines related problems (MRPs) can be common in frail older people due to age-compromised body systems and a propensity to be on multiple drugs concurrently. This group of people can also succumb to a rapid deterioration in health. Thus, it is important to investigate MRPs in frail older people. The objectives of the study were to evaluate prevalence of MRPs, types of MRPs, risk factors and deterioration that can be associated with MRPs in frail older people admitted to an English teaching hospital from primary care...
March 2024: Explor Res Clin Soc Pharm
https://read.qxmd.com/read/38223407/topic-modeling-on-clinical-social-work-notes-for-exploring-social-determinants-of-health-factors
#33
JOURNAL ARTICLE
Shenghuan Sun, Travis Zack, Christopher Y K Williams, Madhumita Sushil, Atul J Butte
OBJECTIVE: Existing research on social determinants of health (SDoH) predominantly focuses on physician notes and structured data within electronic medical records. This study posits that social work notes are an untapped, potentially rich source for SDoH information. We hypothesize that clinical notes recorded by social workers, whose role is to ameliorate social and economic factors, might provide a complementary information source of data on SDoH compared to physician notes, which primarily concentrate on medical diagnoses and treatments...
April 2024: JAMIA Open
https://read.qxmd.com/read/38197956/m%C3%A3-llerian-anomalies-in-girls-with-congenital-solitary-kidney
#34
JOURNAL ARTICLE
Laura Walawender, Natasha Santhanam, Benjamin Davies, Y Frances Fei, Daryl McLeod, Brian Becknell
BACKGROUND: The prevalence of Müllerian anomalies (MA) among patients with congenital solitary functioning kidney (SFK) is not well defined. A delay in diagnosis of obstructive MA can increase the risk of poor clinical outcomes. This study describes the prevalence of MA in patients with congenital SFK. METHODS: A retrospective review was performed of patients within the Nationwide Children's Hospital system with ICD9 or ICD10 diagnostic codes for congenital SFK defined as either unilateral renal agenesis (URA) or multicystic dysplastic kidney (MCDK) and confirmed by chart review...
January 10, 2024: Pediatric Nephrology
https://read.qxmd.com/read/38189678/robotic-care-outcomes-project-robocop-for-acute-gallbladder-pathology
#35
JOURNAL ARTICLE
Shannon Greenberg, Marc Abou Assali, Yanli Li, Hannah Bossie, Chris Neighorn, Esther Wu, Kaushik Mukherjee
BACKGROUND: Robotic cholecystectomy is being increasingly used for patients with acute gallbladder disease who present to emergency department, but clinical evidence is limited. We aimed to compare the outcomes of emergent laparoscopic and robotic cholecystectomies in a large real-world database. METHODS: Patients who received emergent laparoscopic or robotic cholecystectomies from 2020 to 2022 were identified from the Intuitive Custom Hospital Analytics database, based on de-identified extraction of electronic health record data from US hospitals...
January 9, 2024: Journal of Trauma and Acute Care Surgery
https://read.qxmd.com/read/38183827/multiple-sclerosis-and-seizures-a-retrospective-observational-study-in-a-multiple-sclerosis-autoimmunity-center-of-excellence
#36
JOURNAL ARTICLE
Emily R Nurre, Anna Shah, Craig J Hansen, Catherine Dowling, Smathorn Thakolwiboon, Yang Mao-Draayer, Temenuzhka G Mihaylova
PURPOSE: The prevalence of epilepsy in patients with multiple sclerosis (MS) is three to six times the prevalence in the general population. Mechanisms resulting in increased seizure risk are not fully understood. Our objective is to characterize patients with MS and epilepsy regarding timing of diagnoses, MS and seizure (SZ) type, EEG findings suggesting cortical dysfunction, frequency of status epilepticus (SE), and seizure freedom. METHODS: This was a single center retrospective study...
February 2024: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/38130443/determinants-of-cancer-incidence-and-mortality-among-people-with-vitamin-d-deficiency-an-epidemiology-study-using-a-real-world-population-database
#37
JOURNAL ARTICLE
Yi-Chen Lai, Yu-Han Chen, Fu-Wen Liang, Yu-Cih Wu, Jhi-Joung Wang, Sher-Wei Lim, Chung-Han Ho
INTRODUCTION: This study aimed to investigate the determinants of cancer incidence and mortality in patients with vitamin D deficiency using a real-world population database. METHODS: We utilized the International Diagnostic Classification Code (ICD9:268 / ICD10: E55) to define patients with vitamin D deficiency. Additionally, the Cox regression model was used to estimate overall mortality and identify potential factors contributing to mortality in cancer patients...
2023: Frontiers in Nutrition
https://read.qxmd.com/read/38128218/cannabis-use-disorders-and-outcome-of-admission-to-intensive-care-a-retrospective-multi-centre-cohort-study
#38
JOURNAL ARTICLE
Laura Renger, Jayesh Dhanani, Elissa Milford, Alexis Tabah, Kiran Shekar, Mahesh Ramanan, Kevin B Laupland
PURPOSE: To identify factors associated with cannabinoid use among patients admitted to ICU and its impact on survival. METHODS: A cohort of adult patients admitted to four public Australian ICUs was assembled. Individuals with mental and behavioural disorders related to cannabinoids were identified using ICD10-AM codes. RESULTS: Of a cohort of 34,680 admissions among 28,689 adults, 292 (0.8%) had an associated diagnosis related to cannabinoids, of which 66% were classified as harmful use, 26% as dependence syndrome/withdrawal state, 4% as psychosis/delirium, and 4% as acute intoxication...
December 20, 2023: Journal of Critical Care
https://read.qxmd.com/read/38065033/a-retrospective-analysis-of-neurogenic-orthostatic-hypotension-in-long-term-care-facility-residents-with-recurrent-falls
#39
JOURNAL ARTICLE
Mehdi Shadmand, Brian Elliott, Jacob Lautze, Ali Mehdirad
INTRODUCTION: Approximately 50 % of residents in long-term care facilities fall yearly and orthostatic hypotension accounts for a significant portion of them. Neurogenic orthostatic hypotension - a subtype of orthostatic hypotension - is important to be recognized as its management is far more complex; undertreatment of these older adults can lead to recurrent falls, high healthcare cost burden, and increased morbidity and mortality. The primary purpose of our study was to describe the rate of neurogenic orthostatic hypotension in older adults in a long-term care facility, with a secondary purpose to describe risk factors for neurogenic orthostatic hypotension in this population...
December 5, 2023: Autonomic Neuroscience: Basic & Clinical
https://read.qxmd.com/read/38055788/shift-work-and-evening-chronotype-are-associated-with-hepatic-fat-fraction-and-non-alcoholic-fatty-liver-disease-in-282-303-uk-biobank-participants
#40
JOURNAL ARTICLE
Robert Maidstone, Martin K Rutter, Thomas Marjot, David W Ray, Matthew Baxter
BACKGROUND AND AIMS: Non-alcoholic fatty liver disease (NAFLD) has rapidly become the most common liver disease world-wide. Modern lifestyles have been linked to this rise in prevalence with changes in rhythmic human behaviour emerging as a possible mechanism. We investigated how shift working patterns and chronotype were associated with hepatic fat fraction and NAFLD in 282,303 UK Biobank participants. METHODS: We stratified participants into day, irregular-shift, and permanent night-shift workers...
December 1, 2023: Endocrine Connections
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