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post hysterectomy ovarian cancer

Juhua Luo, Michael Hendryx, JoAnn E Manson, XiaoYun Liang, Karen L Margolis
CONTEXT: Estrogen has been suggested as a risk factor for thyroid cancer. OBJECTIVE: The aim of this study is to examine the associations between hysterectomy, bilateral salpingo-oophorectomy (BSO), and incidence of thyroid cancer. DESIGN: This was a prospective cohort study. SETTING: The study was conducted at 40 clinical centers in the United States. PARTICIPANTS: A total of 127 566 women aged 50-79 were enrolled in the Women's Health Initiative during 1993-1998...
October 2016: Journal of Clinical Endocrinology and Metabolism
Anne Craveiro Brøchner, Søren Mikkelsen, Iørn Hegelund, Marianne Hokland, Ole Mogensen, Palle Toft
INTRODUCTION: The treatment of women with ovarian cancer in advanced stages consists of extensive surgery followed by chemotherapy initiated three weeks after surgery. In this study, selected immune parameters were investigated to elucidate when the immune system is normalised following the operation. METHODS: Ten women undergoing extensive surgery for ovarian cancer were compared with a control group of ten women undergoing abdominal hysterectomy for a benign diagnosis...
June 2016: Danish Medical Journal
Brandon T Sawyer, Christopher J LaFargue, Robert E Bristow
OBJECTIVE: The completeness of primary cytoreductive surgery for Stage IV epithelial ovarian cancer is associated with greater progression free survival and overall survival Winter et al. (2008) [1]. Cytoreduction to no gross residual disease in patients with bulky upper abdominal disease presents significant surgical challenges, highlighting the importance of specialized and comprehensive surgical training in the treatment of advanced ovarian cancers Zivanovic et al. (2008) [2]. Extensive upper abdominal surgical procedures have shown to improve the ability to achieve cytoreduction to no gross residual disease Chi et al...
August 2016: Gynecologic Oncology
Jason D Wright, Ling Chen, Soledad Jorge, William M Burke, Ana I Tergas, June Y Hou, Jim C Hu, Alfred I Neugut, Cande V Ananth, Dawn L Hershman
OBJECTIVE: Extended-duration thromboprophylaxis for 4weeks after discharge has been demonstrated to reduce venous thromboembolic events (VTE) in cancer patients undergoing abdominopelvic surgery and is recommended in national guidelines. We examined the utilization and effectiveness of extended-duration low molecular weight heparin prophylaxis in high-risk cancer patients. METHODS: We analyzed patients with colon, ovarian, and uterine cancer who underwent surgery from 2009 to 2013 and who were recorded in the MarketScan database...
June 2016: Gynecologic Oncology
Benito Chiofalo, Jacopo Di Giuseppe, Lara Alessandrini, Tiziana Perin, Giorgio Giorda, Vincenzo Canzonieri, Francesco Sopracordevole
BACKGROUND: Three primary synchronous cancers in the female genital tract are extremely rare. In the literature, only four studies have described three different invasive gynecologic cancers of epithelial origin identified simultaneously in the same patient. CASE PRESENTATION: This is the first case in the literature that reports on triple primary ovarian, endometrial and endocervical cancers in a 38-year-old woman with a history of previously treated malignant disease (acute lymphatic leukemia)...
June 2016: Pathology, Research and Practice
Salvatore Gueli Alletti, Carolina Bottoni, Francesco Fanfani, Valerio Gallotta, Vito Chiantera, Barbara Costantini, Francesco Cosentino, Alfredo Ercoli, Giovanni Scambia, Anna Fagotti
BACKGROUND: Laparoscopy has acquired an increasing role in the management of ovarian cancer. Laparoscopic cytoreduction could represent a new frontier for selected patients after neoadjuvant chemotherapy (NACT). OBJECTIVE: We sought to assess feasibility and early complication rate of minimally invasive (MI) interval debulking surgery (IDS) in stage III-IV epithelial ovarian cancer (EOC) patients after NACT. STUDY DESIGN: This is a phase II multicentric study in advanced EOC cases with clinical complete response after NACT, according to Gynecologic Cancer Intergroup and Response Evaluation Criteria In Solid Tumors criteria...
April 2016: American Journal of Obstetrics and Gynecology
L Cobellis, M A Castaldil, V Frega, L Mosca, F Corvino, S Cappabianca, N Colacurci
PURPOSE OF INVESTIGATION: Miillerian anomalies have not been implicated as a significant risk factor for the development of cervical, uterine, and ovarian cancers; in the present literature, there are only a few reports of endometrial cancer arising in patients with Miillerian abnormalities. To the best of the authors' knowledge, this is the first reported case of endometrial cancer arising in a patient with unicornuate uterus. CASE REPORT: A 69-year-old Caucasian woman underwent clinical examination and office hysteroscopy with endometrial biopsy because of abnormal post-menopausal bleeding...
2015: European Journal of Gynaecological Oncology
Jessica L Chan, Joseph Letourneau, Wael Salem, Aylin Pelin Cil, Sai-Wing Chan, Lee-May Chen, Mitchell P Rosen
OBJECTIVE: To determine if sexual satisfaction and sexual quality of life (QOL) are different in survivors of localized cervical and ovarian cancers who undergo fertility-sparing surgery (FSS) as compared with standard surgery. METHODS: 470 survivors of localized cervical and ovarian cancers diagnosed between the ages of 18-40 were recruited from the California Cancer Registry to complete a cross-sectional survey. Validated questionnaires were used to assess sexual satisfaction and sexual QOL...
October 2015: Gynecologic Oncology
Xiaqin Zhu, Ming Wu, Xianjie Tan, Qi Yu
OBJECTIVE: To explore the clinicopathologic features, managements and outcomes of villoglandular adenocarcinoma (VA) of uterine cervix. METHODS: From June 2009 to January 2014, a total of 16 cases of VA were reviewed retrospectively. RESULTS: Their mean age was 41.4 (30-56) years. The major symptoms were post-coital hemorrhage or abnormal vaginal hemorrhage (10/16). And the International Federation of Gynecology and Obstetrics (FIGO) stages were Ia1 (n = 1),Ib1 (n = 12),Ib2 (n = 2) and IIa1 (n = 1)...
February 17, 2015: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Magali Robert, David Cenaiko, Jasmine Sepandj, Stanislaw Iwanicki
STUDY OBJECTIVES: To document the success rates and complications of salpingectomy performed at the time of vaginal hysterectomy to possibly reduce ovarian cancer rates. DESIGN: Retrospective cohort study (Canadian Task Force Classification II-2). SETTING: Community-based hospital with university affiliation in Calgary, Canada. INTERVENTION: All women undergoing hysterectomy for benign conditions were offered preferentially a vaginal approach with prophylactic salpingectomy...
July 2015: Journal of Minimally Invasive Gynecology
Katsunori Ami, Kentarou Gokita, Yousuke Kawai, Yutarou Matsunaga, Keiichi Fujiya, Nana Ohshima, Hidetoshi Amagasa, Hideaki Ganno, Kenichirou Imai, Akira Fukuda, Takeshi Nagahama, Masayuki Ando, Youichi Okada, Hidetaka Akita, Shikofumi Tei, Yousuke Yamada, Mariko Takagi, Fumi Kodaka, Kuniyoshi Arai
Stage IV gastric cancer has poor prognosis, and median survival time (MST) is reported to range from 6 to 13 months. We report a case of long-term survival in a Stage IV gastric cancer patient who was successfully treated with multi combination chemotherapy with S-1. A 73-year-old woman presenting with gastric cancer with pyloric stenosis and peritoneal dissemination at the sigmoid colon underwent distal gastrectomy with D2 lymphadenectomy and sigmoidectomy. She received adjuvant chemotherapy with S-1 and CDDP after surgery...
November 2014: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Avanish Kumar Saxena, Nitin Goyal, Juhi Singhal, Parveen Kumar
Axillary lymph node metastasis from primary ovarian cancer is rare. Here, we reporting a unique case of 45 years old who presented with axillary lymph node metastasis which was thought from breast carcinoma but it turned out to be due to ovarian serous adenocarcinoma confirmed by histopathology & immunohistochemistry. Staging laparotomy (IIIc) with hysterectomy with bilateral salpingo-oophorectomy was done. Post-operatively, the patient was given adjuvant chemotherapy. No local or systemic recurrence was noted during 1 year follow up period...
September 2014: Indian Journal of Surgical Oncology
Ramona Moldovan, Sianan Keating, Tara Clancy
Women with Lynch syndrome (LS) have a significantly increased lifetime risk of endometrial cancer (40-60 %) and ovarian cancer (7-12 %). Currently there is little evidence to support the efficacy of screening for the early detection of these cancers. Another option is risk-reducing hysterectomy and/or bilateral salpingo-oophorectomy (BSO). Research on the impact of BSO in premenopausal women with a non-LS associated family history cancer has generally shown that women have a high level of satisfaction about their decision to undergo surgery...
March 2015: Familial Cancer
Tayfun Gungor, Nilufer Cetinkaya, Hakan Yalcin, Bulent Ozdal, Emre Ozgu, Eralp Baser, Dilek Uygur, Mete Caglar, Levent Sirvan, Salim Erkaya
PURPOSE: Borderline ovarian tumors (BOTs) constitute about a quarter of epithelial ovarian malignancies and require different treatment approaches. The present study aims to document the experience of a single center on the treatment outcome of women who had conservative or comprehensive surgery for BOTs. METHODS: One hundred eighty-three patients with BOTs, diagnosed and/or treated in our center between January of 2000 and March of 2013, were reviewed retrospectively...
January 2015: Archives of Gynecology and Obstetrics
Susan J Jordan, Christina M Nagle, Michael D Coory, Diane Maresco, Melinda M Protani, Neha A Pandeya, Kanchana D Balasubramaniam, Penelope M Webb
Until recently most studies suggested that hysterectomy with ovarian conservation was associated with a decreased risk of ovarian cancer. However, several recent studies have reported modestly increased risks of ovarian cancer following hysterectomy. Given that as many as 35% of women will have a hysterectomy, the nature of the association requires clarification. We conducted a systematic review and meta-analysis of the published literature on the relationship between hysterectomy and ovarian cancer to investigate whether there has been a temporal change in the association...
November 2013: European Journal of Cancer
Ayse Kubat Uzum, Cem Iyibozkurt, Bulent Canbaz, Sema Dogansen Ciftci, Nihat Aksakal, Yersu Kapran, Ferihan Aral, Nese Colak Ozbey
Thyroid cancer in ovarian teratoma is reported to be rare and experiences are limited. A 26-year-old woman had undergone bilateral cystectomy and omentectomy for bilateral cystic adnexial masses. Pathological examination showed 1.5 cm follicular variant papillary thyroid carcinoma on the basis of unilateral mature cystic teratoma. Increased CA-125 and CA19-9 levels decreased to normal reference ranges after surgery, but postoperative magnetic resonance imaging indicated multiple abdominal cystic loci. After total thyroidectomy, high dose I-131 was administered to ablate thyroid tissue...
July 2013: Gynecological Endocrinology
Anita J Merritt, Emma J Crosbie, Judith Charova, Josephine Achiampong, Ilze Zommere, Brett Winter-Roach, Richard J Slade
PURPOSE: The use of prophylactic pre-operative bilateral ureteric catheters for major gynaecological surgery is controversial. The aim of this study was to investigate the frequency of ureteric catheter-associated morbidity in our Unit, where systematic pre-operative ureteric catheterisation is performed. METHODS: We conducted a retrospective casenote review of 337 gynaecology patients undergoing laparotomy at Salford Royal Hospital between January 2007 and September 2010...
November 2013: Archives of Gynecology and Obstetrics
Firas Obeidat, Ayman Mismar, Maha Shomaf, Mohammad Yousef, Kamil Fram
INTRODUCTION: Metastasis from ovarian cancer occurs frequently through the peritoneal cavity in the form of peritoneal carcinomatosis; isolated gastric metastasis is rarely reported in literature. PRESENTATION OF CASE: We present a case of 43-year-old infertile lady, who developed a picture of acute abdomen four days post total abdominal hysterectomy and salpingoopherectomy for ovarian cancer. Further contrast-enhanced CT scan demonstrated massive free gas and fluid in the abdomen...
2013: International Journal of Surgery Case Reports
Michele Morelli, Roberta Venturella, Rita Mocciaro, Annalisa Di Cello, Erika Rania, Daniela Lico, Pietro D'Alessandro, Fulvio Zullo
OBJECTIVE: The objective of this study is to compare ovarian function and surgical outcomes between patients affected by benign uterine pathologies submitted to total laparoscopic hysterectomy (TLH) plus salpingectomy and women in which standard TLH with adnexal preservation was performed. METHODS: We retrospectively compared data of 79 patients who underwent TLH plus bilateral salpingectomy (group A), with those of 79 women treated by standard TLH without adnexectomy (sTLH) (group B)...
June 2013: Gynecologic Oncology
Pn Shakuntala, K Umadevi, A Usha, N Abhilasha, Ud Bafna
OBJECTIVE: Ovarian adenosarcoma is a very rare tumour for which treatment options vary. We will consider the option of optimal cytoreductive surgery followed by adjuvant chemotherapy consisting of ifosamide (mesna) and adriamycin to prevent systemic metastasis, and will observe the role of serial CA-125 levels as a follow-up marker. CASE REPORT: We report a case of ovarian adenosarcoma in a 38-year-old woman presenting with abdominal pain, distention due to massive ascites...
2012: Ecancermedicalscience
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