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https://www.readbyqxmd.com/read/29665643/evaluation-of-the-effects-of-iranian-propolis-on-the-severity-of-post-operational-induced-peritoneal-adhesion-in-rats
#1
Vahid Reza Askari, Vafa Baradaran Rahimi, Parvin Zamani, Narges Fereydouni, Pouria Rahmanian-Devin, Amir Hossein Sahebkar, Hassan Rakhshandeh
BACKGROUND: Peritoneal adhesion is a major complication of surgery that can lead to serious problems such as bowel obstruction, pain, infertility and even mortality. Propolis is a honey bee product with anti-inflammatory and anti-oxidant activities that could potentially protect against adhesive surgical complications. METHODS: Forty 8-weeks-old rats (275 ± 25 g) were divided into five groups: normal group without any surgical procedure, and experimental groups treated with normal saline, 50 mg/kg, 100 mg/kg and 200 mg/kg of propolis...
March 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29665628/effect-of-topical-propolis-on-wound-healing-process-after-tonsillectomy-randomized-controlled-study
#2
Jeong Hwan Moon, Min Young Lee, Young-Jun Chung, Chung-Ku Rhee, Sang Joon Lee
Objectives: The post-tonsillectomy pain and post-tonsillectomy hemorrhage are the two main problems after tonsillectomy. The aim of this study was to investigate the beneficial effects of water soluble ethanol extract propolis on post-tonsillectomy patient. Methods: One hundred and thirty patients who underwent tonsillectomy or adenotonsillectomy were randomly divided into the control and propolis groups, each including 65 patients. The propolis group was applied with propolis orally immediately after surgery and by gargle...
December 28, 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/29665415/antitrypanosomal-antileishmanial-and-cytotoxic-activities-of-brazilian-red-propolis-and-plant-resin-of-dalbergia-ecastophyllum-l-taub
#3
Marcos da Silveira Regueira-Neto, Saulo Relison Tintino, Miriam Rolón, Cathia Coronal, Maria C Vega, Valdir de Queiroz Balbino, Henrique Douglas de Melo Coutinho
The treatment for leishmaniasis and Chagas disease can be hard and painful, such that many patients give up on the treatment. In order to find an alternative path for the treatment of these diseases, researchers are using natural products to fight these parasites. The aim of this study was to evaluate the antiprotozoan and cytotoxic activities of red propolis samples collected from different Brazilian states and seasons whilst searching for possible activity differences. We also compared the red propolis results with the ones obtained for the plant resin extract collected from Dalbergia ecastophyllum trees...
April 14, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29665251/human-periodontal-fibroblasts-viability-stored-in-custodiol-%C3%A2-coconut-water-and-propolis-an-ex-vivo-study
#4
Lama Awawdeh, Rana Naman Haimour, Suhad Hussein Al-Jundi, Khaled Al-Qaoud
BACKGROUND/AIMS: Successful replantation of an avulsed tooth depends on the regeneration of periodontal ligament (PDL) attachment which is affected by the transport medium, dry time and storage time. Various storage media have been studied but the search for the optimum storage medium is still needed to determine the ideal material and storage time to maintain PDL cells. The aim of this study was to determine the ability of Custodiol® , coconut water from different stages of maturity and propolis as storage media for avulsed teeth by evaluating the viability of PDL cells for different time intervals...
April 17, 2018: Dental Traumatology: Official Publication of International Association for Dental Traumatology
https://www.readbyqxmd.com/read/29657421/expression-of-vascular-endothelial-growth-factor-and-matrix-metalloproteinase-9-in-apis-mellifera-lawang-propolis-extract-gel-treated-traumatic-ulcers-in-diabetic-rats
#5
Diah Savitri Ernawati, Ade Puspa
Aim: The aim of this study was to determine the effect of Apis mellifera propolis extract gel on vascular endothelial growth factor (VEGF) and matrix metalloproteinase-9 (MMP-9) expression in the traumatic ulcers of rats afflicted with diabetes mellitus (DM). Materials and Methods: The study was conducted on 24 male Wistar rats ( Rattus norvegicus ) induced with DM by injecting 50 mg/kg of Streptozotocin, intraperitoneally, and a traumatic ulcer on their lower lip mucosa...
March 2018: Veterinary World
https://www.readbyqxmd.com/read/29642950/melliferous-insects-and-the-uses-assigned-to-their-products-in-the-northern-yungas-of-salta-argentina
#6
Fabio Fernando Flores, Norma Inés Hilgert, Liliana Concepción Lupo
BACKGROUND: The order Hymenoptera comprises melliferous insects (bees, wasps and bumblebees); among them, stingless bees comprise a diverse group of eusocial insects present in tropical and subtropical areas. Of a total of approximately 500 species, 400 are found in the Neotropics. On the continent of America, before the introduction of Apis mellifera, these insects represented the main source of honey and wax. In Argentina, ethnobiological investigations had been carried out on this group of insects, principally in the Atlantic Forest and Chaco regions...
April 11, 2018: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/29642541/influence-of-dietary-supplementation-of-propolis-and-bee-pollen-on-liver-pathology-in-broiler-chickens
#7
Ivana Klaric, Mirela Pavic, Ivan Miskulin, Valerija Blazicevic, Albina Dumic, Maja Miskulin
One of the major problems in intensive breeding of chickens is liver damage. The objective of this study was to determine the influence of dietary supplementation with propolis and bee pollen on liver pathology in broiler chickens. The study was conducted on 200 Ross 308 chickens equally distributed by sex that were divided into five groups. Throughout the whole study, the control group of chickens was fed with a basal diet, while the experimental groups of chickens were fed with the same diet further supplemented with propolis and bee pollen, each supplement given separately or in combination in a certain proportion...
April 9, 2018: Animals: An Open Access Journal From MDPI
https://www.readbyqxmd.com/read/29642511/effect-of-pinocembrin-isolated-from-mexican-brown-propolis-on-diabetic-nephropathy
#8
Jessica Granados-Pineda, Norma Uribe-Uribe, Patricia García-López, María Del Pilar Ramos-Godinez, J Fausto Rivero-Cruz, Jazmin Marlen Pérez-Rojas
Propolis is a resinous beehive product that has been used worldwide in traditional medicine to prevent and treat colds, wounds, rheumatism, heart disease and diabetes. Diabetic nephropathy is the final stage of renal complications caused by diabetes and for its treatment there are few alternatives. The present study aimed to determine the chemical composition of three propolis samples collected in Chihuahua, Durango and Zacatecas and to evaluate the effect of pinocembrin in a model of diabetic nephropathy in vivo...
April 9, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29611326/inhibitory-effect-of-thai-propolis-on-human-osteoclastogenesis
#9
Nattaporn Wimolsantirungsri, Anupong Makeudom, Phumisak Louwakul, Thanapat Sastraruji, Pattama Chailertvanitkul, Chayarop Supanchart, Suttichai Krisanaprakornkit
BACKGROUND/AIM: Avulsed teeth should be immediately replanted into the socket or otherwise kept in a physiologic storage medium to maintain periodontal ligament cell viability. A previous study has demonstrated that Thai propolis extract can maintain viability of human periodontal ligament cells. However, root resorption by osteoclasts often occurs when the avulsed teeth are replanted. The aim of this study was to determine the inhibitory effect of Thai propolis extract on human osteoclastogenesis in vitro...
April 3, 2018: Dental Traumatology: Official Publication of International Association for Dental Traumatology
https://www.readbyqxmd.com/read/29607839/antibacterial-effect-of-propolis-derived-from-tribal-region-on-streptococcus-mutans-and-lactobacillus-acidophilus-an-in-vitro-study
#10
Bhuvnesh Airen, Priyanka Airen Sarkar, Urvashi Tomar, Kundendu Arya Bishen
Aim: The study aimed at investigating in vitro antimicrobial activity of ethanolic extract of propolis (EEP) and water extract of propolis against two main cariogenic oral pathogens: Streptococcus mutans and Lactobacillus acidophilus. Material and Methodology: Propolis was obtained from beehives in the Jhabua region of India. Ethanolic and water extracts were prepared at concentrations of 5% and 20% weight/volume (w/v). To support the results, a positive control (chlorhexidine 0...
January 2018: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/29603556/caffeic-acid-phenethyl-ester-guards-against-benign-prostate-hypertrophy-in-rats-role-of-igf-1r-protein-kinase-b-akt-%C3%AE-catenin-signaling
#11
Hany A Omar, Mai F Tolba
Benign prostate hypertrophy (BPH) is among the most common diseases with a huge impact on the quality of life of elderly men. There is a current need for the development of well-tolerated and effective preventive strategies to improve the clinical outcome. Caffeic acid phenethyl ester (CAPE) is an important active ingredient isolated from honey-bee propolis with potent anti-proliferative, anti-inflammatory and antioxidant effects. These properties promote CAPE as a promising candidate to be tested as an alternative therapy for BPH, which is still uninvestigated...
March 30, 2018: IUBMB Life
https://www.readbyqxmd.com/read/29599587/to-evaluate-the-efficacy-of-topical-propolis-in-the-management-of-symptomatic-oral-lichen-planus-a-randomized-controlled-trial
#12
Athira Joshy, Nagabhushana Doggalli, Karthikeya Patil, P K Kulkarni
Introduction: Lichen planus (LP) is a chronic inflammatory, autoimmune, mucocutaneous disease of unknown etiology. The first line of treatment for oral LP (OLP) has been corticosteroids, but because of their adverse effects, alternative therapeutic approaches are being carried out, of which the recent natural alternative is propolis. Aim: This study aims to evaluate the efficacy of topical propolis in the management of OLP. Materials and Methods: The research group consisted of 27 patients diagnosed with symptomatic OLP, among which 15 patients were in the control group and the rest 12 were in the study group...
January 2018: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/29597147/caffeic-acid-phenethyl-ester-down-regulates-claudin-2-expression-at-the-transcriptional-and-post-translational-levels-and-enhances-chemosensitivity-to-doxorubicin-in-lung-adenocarcinoma-a549-cells
#13
Hiroyuki Sonoki, Asami Tanimae, Takumi Furuta, Satoshi Endo, Toshiyuki Matsunaga, Kenji Ichihara, Akira Ikari
Claudin-2 is highly expressed in human lung adenocarcinoma cells and involved in the promotion of proliferation. Here, we searched for a compound, which can decrease claudin-2 expression using lung adenocarcinoma A549 cells. In the screening using compounds included in royal jelly and propolis, the protein level of claudin-2 was dose-dependently decreased by caffeic acid phenethyl ester (CAPE), whereas the mRNA level and promoter activity were only decreased by 50 μM CAPE. These results suggest that CAPE down-regulates claudin-2 expression mediated by two different mechanisms...
March 2, 2018: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/29579994/standardizing-the-analysis-of-phenolic-profile-in-propolis
#14
Isabel Escriche, Marisol Juan-Borrás
The analysis of propolis is controversial, hampering the comparison of its biological properties and estimation of its commercial value. This work evaluates the effectiveness of combining maceration and ultrasonication extraction techniques on the yield, total phenol content (Folin-Ciocalteau) and the specific phenolic compounds (HPLC-UV), on propolis from different origins. The extraction method was not significant in any case; therefore ultrasonication is recommended (time-saving) but only when a double extraction is performed...
April 2018: Food Research International
https://www.readbyqxmd.com/read/29579978/cytotoxic-proapoptotic-and-antioxidative-potential-of-flavonoids-isolated-from-propolis-against-colon-hct-116-and-breast-mda-mb-231-cancer-cell-lines
#15
Nenad L Vukovic, Ana D Obradovic, Milena D Vukic, Danijela Jovanovic, Predrag M Djurdjevic
Isolated and structurally confirmed, eleven flavonoids from propolis were examined for their cytotoxicity toward human colon cancer and human breast cancer cells. Their effect on induction of apoptosis and their antioxidative activities were also evaluated. Six flavonoids induced cytotoxic effects in both cell lines. Luteolin had a marked effect on both cell lines, especially on HCT-116 cells (IC50 72h, 66.86μM). Also, luteolin was observed to have the highest apoptotic potential after 72h treatment of examined cell lines (27...
April 2018: Food Research International
https://www.readbyqxmd.com/read/29567247/antibacterial-activity-of-propolins-from-taiwanese-green-propolis
#16
Yue-Wen Chen, Siou-Ru Ye, Chieh Ting, Yu-Hsiang Yu
Taiwanese green propolis is a prenylated flavonoid rich honeybee product and propolins isolated from Taiwanese green propolis exert a broad spectrum of biological activities, such as anti-cancer and anti-oxidant. However, the anti-bacterial effects of Taiwanese green propolis or propolins are still poorly understood. In the current study, the antibacterial effects of Taiwanese green propolis and propolins were evaluated. Results show that the maximum dry matter yields of Taiwanese green propolis were observed in the 95% and 99...
April 2018: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/29562665/chemical-composition-and-antioxidant-activity-of-propolis-prepared-in-different-forms-and-in-different-solvents-useful-for-finished-products
#17
Fabio Galeotti, Francesca Maccari, Alfredo Fachini, Nicola Volpi
Different products from a unique propolis extract obtained by using various solvents such as hydroalcoholic, glycolic (98% propylene glycol), and glyceric solutions, and oil, as well as in powder form, named ESIT12, were prepared. The molecular composition of the different preparations was evaluated and their antioxidant activity determined. All the preparations showed a quite similar polyphenol composition and comparable percentage even if ESIT12 was found to be richer in phenolic acids (caffeic, coumaric, ferulic, and isoferulic)...
March 19, 2018: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/29554652/efficacy-of-a-propolis-based-syrup-faringel-in-preventing-radiation-induced-esophagitis-in-locally-advanced-lung-cancer
#18
Edy Ippolito, Barnaba Floreno, Carla Germana Rinaldi, Lucio Trodella, Federica Loretta Meroni, Aurelia Iurato, Rolando Maria D'Angelillo, Sara Ramella, Michele Fiore
AIM: To evaluate the efficacy of a propolis-based syrup, FARINGEL®, in preventing radiation-induced esophagitis in locally advanced lung cancer patients. METHODS: Patients were treated with concurrent chemoradiotherapy (CRT) using involved-field radiotherapy (RT). Every patient received FARINGEL at the beginning of CRT until the first follow-up. The data of the study group were compared with the data of a control group treated without the administration of the syrup...
March 19, 2018: Chemotherapy
https://www.readbyqxmd.com/read/29548452/microencapsulation-of-caffeic-acid-phenethyl-ester-and-caffeic-acid-phenethyl-amide-by-inclusion-in-hydroxypropyl-%C3%AE-cyclodextrin
#19
E Manuela P J Garrido, Ana S Cerqueira, Daniel Chavarria, Tiago Silva, Fernanda Borges, Jorge M P J Garrido
Caffeic acid phenethyl ester (CAPE) is a bioactive polyphenolic compound obtained from propolis extract. Although it has a broad therapeutic potential, the bioavailability of CAPE is limited, due to reduced solubility and poor plasmatic stability. Efforts to reduce these pharmacokinetic drawbacks resulted in the synthesis of caffeic acid phenethyl amide (CAPA). Cyclodextrins have been proved as promising excipients for the formulation of active ingredients. Herein, we report the inclusion complexation behavior and binding ability of CAPE and CAPA with hydroxypropyl-β-cyclodextrin (HP-β-CD)...
July 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29526202/inhibitory-activity-of-propolis-against-listeria-monocytogenes-in-milk-stored-under-refrigeration
#20
Ioannis-Angelos I Thamnopoulos, Georgios F Michailidis, Dimitrios J Fletouris, Anastasia Badeka, Michael G Kontominas, Apostolos S Angelidis
Propolis is a natural bee-product with documented antimicrobial properties in vitro. The objective of this study was to develop a protocol for adding propolis into milk and to determine whether the addition of propolis can confer anti-listerial activity during the storage of milk under optimal or improper refrigeration conditions. Upon dissolving propolis ethanolic extract (PEE) into glycerol, the PEE-glycerol mixture contained no visible insoluble particles and could be dispersed evenly into milk, without leaving any insoluble material...
August 2018: Food Microbiology
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