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https://www.readbyqxmd.com/read/28319671/amelioration-of-oxidative-stress-by-dietary-fenugreek-trigonella-foenum-graecum-l-seeds-is-potentiated-by-onion-allium-cepa-l-in-streptozotocin-induced-diabetic-rats
#1
Seetur R Pradeep, Krishnapura Srinivasan
Oxidative stress has a crucial role in the progression of diabetes and its complications. Soluble fibre-rich fenugreek seeds (Trigonella foenum-graecum L.) are understood to have a beneficial effect in the management of diabetes. Previously, we have shown that the amelioration of diabetic hyperglycemia and related metabolic abnormalities was potentiated by onion (Allium cepa L.) in experimental rats. The present study evaluated the additive beneficial effect of dietary fenugreek seeds (10%) and onion (3%) on oxidative stress in diabetic rats...
March 20, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28300729/comparison-of-silicon-nanoparticles-and-silicate-treatments-in-fenugreek
#2
Sanam Nazaralian, Ahmad Majd, Saeed Irian, Farzaneh Najafi, Farrokh Ghahremaninejad, Tommy Landberg, Maria Greger
Silicon (Si) fertilization improves crop cultivation and is commonly added in the form of soluble silicates. However, most natural plant-available Si originates from plant formed amorphous SiO2 particles, phytoliths, similar to SiO2-nanoparticles (SiNP). In this work we, therefore, compared the effect by sodium silicate and that of SiNP on Si accumulation, activity of antioxidative stress enzymes catalase, peroxidase, superoxide dismutase, lignification of xylem cell walls and activity of phenylalanine ammonia-lyase (PAL) as well as expression of genes for the putative silicon transporter (PST), defensive (Tfgd 1) and phosphoenolpyruvate carboxykinase (PEPCK) and protein in fenugreek (Trigonella foenum-graecum L...
March 14, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28283164/case-reports-of-peanut-fenugreek-and-cashew-sumac-cross-reactivity
#3
Chun T Che, Lindsay Douglas, Joel Liem
No abstract text is available yet for this article.
March 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28269780/fenugreek-seed-powder-attenuated-aluminum-chloride-induced-tau-pathology-oxidative-stress-and-inflammation-in-a-rat-model-of-alzheimer-s-disease
#4
Asokan Prema, Arokiasamy Justin Thenmozhi, Thamilarasan Manivasagam, Musthafa Mohamed Essa, Gilles J Guillemin
Alzheimer's disease (AD) is a common neurodegenerative disorder that mainly affects the aged population and is characterized by the progressive loss of the hippocampal and cortical neurons, which results in memory and cognitive impairments. Trigonella foenum-graecum (fenugreek) has been reported to have hypoglycemic, hypocholesterolemic, hyperinsulinemic and anti-diabetic properties. Traditionally, it was used as a galactagogue and to treat anorexia, fever gastritis, gastric ulcers, and various nervous disorders...
February 25, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28266134/a-small-plant-with-big-benefits-fenugreek-trigonella-foenum-graecum-linn-for-disease-prevention-and-health-promotion
#5
REVIEW
Kalyan C Nagulapalli Venkata, Debasis Bagchi, Anupam Bishayee
Plant-derived natural products have long-standing utility towards treating degenerative diseases. It is estimated that about two-third of world population depend on traditional medicine for primary medical needs. Fenugreek (Trigonella foenum-graecum Linn.), a short-living annual medicinal plant belonging to Fabaceae family, is used extensively in various parts of the world as herb, food, spice and traditional medicine. Fenugreek is considered as one of the oldest medicinal plants and its health-promoting effects have been cited in Ayurveda and traditional Chinese medicine...
March 7, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28229130/traits-affecting-early-season-nitrogen-uptake-in-nine-legume-species
#6
Elana Dayoub, Christophe Naudin, Guillaume Piva, Steven J Shirtliffe, Joëlle Fustec, Guénaëlle Corre-Hellou
Legume crops are known to have low soil N uptake early in their life cycle, which can weaken their ability to compete with other species, such as weeds or other crops in intercropping systems. However, there is limited knowledge on the main traits involved in soil N uptake during early growth and for a range of species. The objective of this research was to identify the main traits explaining the variability among legume species in soil N uptake and to study the effect of the soil mineral N supply on the legume strategy for the use of available N sources during early growth...
February 2017: Heliyon
https://www.readbyqxmd.com/read/28199188/trigonella-seed-extract-ameliorates-inflammation-via-regulation-of-the-inflammasome-adaptor-protein-asc
#7
Nidhi Sharma, Samyuktha Suresh, Ananya Debnath, Sushmita Jha
Trigonella foenum-graecum (fenugreek) is an important medicinal plant, well known for its anti-inflammatory properties. However, the underlying cellular and molecular mechanisms of its action remain largely unknown. The apoptosis associated speck like protein containing a caspase recruitment domain (CARD) (ASC) is central to inflammatory and cell death pathways in innate and adaptive immunity. Here, we show that fenugreek seed extract provides cytoprotection to bacterial lipopolysaccharide (LPS) inflammed and nanosilica-treated fibroblasts via a reactive oxygen species independent pathway...
March 1, 2017: Frontiers in Bioscience (Elite Edition)
https://www.readbyqxmd.com/read/28161815/next-generation-sequencing-of-representational-difference-analysis-products-for-identification-of-genes-involved-in-diosgenin-biosynthesis-in-fenugreek-trigonella-foenum-graecum
#8
Joanna Ciura, Magdalena Szeliga, Michalina Grzesik, Mirosław Tyrka
Representational difference analysis of cDNA was performed and differential products were sequenced and annotated. Candidate genes involved in biosynthesis of diosgenin in fenugreek were identified. Detailed mechanism of diosgenin synthesis was proposed. Fenugreek (Trigonella foenum-graecum L.) is a valuable medicinal and crop plant. It belongs to Fabaceae family and has a unique potential to synthesize valuable steroidal saponins, e.g., diosgenin. Elicitation (methyl jasmonate) and precursor feeding (cholesterol and squalene) were used to enhance the content of sterols and steroidal sapogenins in in vitro grown plants for representational difference analysis of cDNA (cDNA-RDA)...
February 4, 2017: Planta
https://www.readbyqxmd.com/read/28157172/extraction-of-fenugreek-trigonella-foenum-graceum-l-seed-oil-using-subcritical-butane-characterization-and-process-optimization
#9
Ling-Biao Gu, Xiao-Ning Liu, Hua-Min Liu, Hui-Li Pang, Guang-Yong Qin
In this study, the subcritical butane extraction process of fenugreek seed oil was optimized using response surface methodology with a Box-Behnken design. The optimum conditions for extracted oil from fenugreek seed was as follows: extraction temperature of 43.24 °C , extraction time of 32.80 min, and particle size of 0.26 mm. No significant differences were found between the experimental and predicted values. The physical and chemical properties of the oil showed that the oil could be used as edible oil. Fatty acid composition of oils obtained by subcritical butane under the optimum conditions and by accelerated solvent extraction showed negligible difference...
February 2, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28156165/preclinical-safety-assessment-of-furostanol-glycoside-based-standardized-fenugreek-seed-extract-in-laboratory-rats
#10
Pallavi Deshpande, Vishwaraman Mohan, Dilip Ingavale, Jyoti Mane, Mukul Pore, Prasad Thakurdesai PhD
The present work is aimed at studying acute oral toxicity (AOT), subchronic oral toxicity, mutagenicity, and genotoxicity of furostanol glycosides-based standardized fenugreek seed extract (Fenu-FG) using the Organization for Economic Co-operation and Development (OECD) guidelines. The AOT and subchronic (90-day repeated dose) toxicity studies were performed on Wistar rats as per OECD 423 and OECD 408 guidelines, respectively. The mutagenicity (reverse mutation assay, Ames test) and genotoxicity (mammalian chromosome aberration test) were assessed in vitro using OECD 471 and OECD 473 guidelines, respectively...
September 3, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/28143746/structure-functional-and-antioxidant-properties-in-tunisian-beef-sausage-of-a-novel-polysaccharide-from-trigonella-foenum-graecum-seeds
#11
Naourez Ktari, Amal Feki, Imen Trabelsi, Mehdi Triki, Hana Maalej, Sirine Ben Slima, Moncef Nasri, Ibtissem Ben Amara, Riadh Ben Salah
A novel polysaccharide named Fenugreek Water-Soluble Polysaccharide (FWSP), consisting of a gluconic acid polymer, was isolated from fenugreek seeds. It was structurally characterized by Fourier transformed infrared (FT-IR), X-ray diffraction (XRD), High performance liquid chromatograpy (HPLC), and Nuclear magnetic resonance (NMR) spectroscopies. FT-IR and NMR spectra showed the characteristic bands of polysaccharides. According to XRD spectrum, FWSP is a semi-crystalline polymer. Functional properties of FWSP were investigated based on Water Holding Capacity (WHC), Oil Holding Capacity (OHC), emulsification activity, and foaming ability...
January 29, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28138310/efficacy-of-furosap-tm-a-novel-trigonella-foenum-graecum-seed-extract-in-enhancing-testosterone-level-and-improving-sperm-profile-in-male-volunteers
#12
Anuj Maheshwari, Narsingh Verma, Anand Swaroop, Manashi Bagchi, Harry G Preuss, Kiran Tiwari, Debasis Bagchi
Background: Dietary fiber rich fenugreek (Trigonella foenum-graecum) seeds have exhibited cardioprotective, hypolipidemic and other health benefits. Furosap (FS), an innovative, patented, 20% protodioscin-enriched extract was developed in our laboratory from fenugreek seeds. This study examined the free and total testosterone levels, sperm profile and morphology, sexual health, mood and mental alertness, and broad spectrum safety parameters of FS in 50 male volunteers following supplementation over a period of 12 weeks...
2017: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/28130295/differential-attachment-of-salmonella-enterica-and-enterohemorrhagic-escherichia-coli-to-alfalfa-fenugreek-lettuce-and-tomato-seeds
#13
Yue Cui, Ronald Walcott, Jinru Chen
Vegetable seeds have the potential to disseminate and transmit foodborne bacterial pathogens. This study was undertaken to assess the abilities of selected Salmonella and enterohemorrhagic Escherichia coli (EHEC) strains to attach to fungicide-treated vs untreated, and intact vs mechanically-damaged seeds of alfalfa, fenugreek, lettuce, and tomato. Surface-sanitized seeds (2 g) were exposed to 4 individual strains of Salmonella or EHEC at 20°C for 5 h. Contaminated seeds were rinsed twice, each with 10 ml of sterilized water before being soaked overnight in 5 ml of phosphate buffered saline at 4 °C...
January 27, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28125204/fenugreek-incorporated-silk-fibroin-nanofibers-a-potential-antioxidant-scaffold-for-enhanced-wound-healing
#14
Sowmya Selvaraj, Nishter Nishad Fathima
Free radicals are generated by various biochemical pathways in the living system, causing severe oxidative damage to the biomolecules leading to adverse disease conditions. Hence, there is an increasing interest in antioxidant studies for preventing the effects of these free radicals. Herein, we propose a novel electrospun scaffold with antioxidant properties that can be used as wound healing material. Fenugreek, a natural antioxidant incorporated silk fibroin nanofiber, was prepared in four different ratios by the co-electrospinning method...
February 22, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28107731/natural-amelioration-of-zinc-oxide-nanoparticle-toxicity-in-fenugreek%C3%A2-trigonella-foenum-gracum-by-arbuscular-mycorrhizal-glomus-intraradices-secretion-of-glomalin
#15
Narges Ghasemi Siani, Seyfollah Fallah, Lok Raj Pokhrel, Ali Rostamnejadi
Owing to rising production and use of engineered nanoparticles (ENPs) in the myriad of consumer applications, ENPs are being released into the environment where their potential fate and effects have remained unclear. With naturally occurring arbuscular mycorrhizal fungus (AMF; Glomus intraradices) in soils, their influence (positive or negative) on ENPs toxicity in plants is not well documented. Herein, we investigated potential influence of AMF on the growth and development in fenugreek (Trigonella foenum-graecum) under varied Zinc oxide nanoparticles (ZnONPs) treatments (0, 125, 250, 375 and 500 μg g(-1))...
January 3, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28092841/phytochemical-study-and-protective-effect-of-trigonella-foenum-graecum-fenugreek-seeds-against-carbon-tetrachloride-induced-toxicity-in-liver-and-kidney-of-male-rat
#16
Sakhria Mbarki, Hichem Alimi, Hafsia Bouzenna, Abdelfettah Elfeki, Najla Hfaiedh
Liver and kidney diseases are a global concern, therefore considerable efforts to obtain fine herbs useful as drugs from medicinal plants are currently in progress. The aim of this work was to study the antioxidant effects of previous supplementation with fenugreek seeds (FS) against carbon tetrachloride (CCl4) toxicity in the liver and kidney. CCl4 toxicity was induced by one dose (i.g. 5ml CCl4/kg of body weight, 50% CCl4 in olive oil) after 7 weeks of normal diet or diet rich in 10% of grinded fenugreek seeds (20g of pellet rat food/rat/day)...
April 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28063302/metabonomics-study-of-the-therapeutic-mechanism-of-fenugreek-galactomannan-on-diabetic-hyperglycemia-in-rats-by-ultra-performance-liquid-chromatography-coupled-with-quadrupole-time-of-flight-mass-spectrometry
#17
Wenyue Jiang, Lu Gao, Pengdong Li, Hong Kan, Jiale Qu, Lihui Men, Zhiqiang Liu, Zhongying Liu
Fenugreek is a traditional plant for the treatment of diabetes. Galactomannan, an active major component in fenugreek seeds, has shown hypoglycemic activity. The present study was performed to investigate the therapeutic mechanism underlying fenugreek galactomannan (F-GAL) in treating diabetes, using a metabonomics approach based on ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UPLC-QTOF/MS). The F-GAL used for study was highly purified, and its yield, purity, and galactose/mannose ratio were characterized by capillary zone electrophoresis (CZE) and a modified phenol-sulfuric acid method...
February 15, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28024532/-aerogels-of-enzymatically-oxidized-galactomannans-from-leguminous-plants-versatile-delivery-systems-of-antimicrobial-peptides-and-enzymes
#18
Paola Campia, Erika Ponzini, Bianca Rossi, Stefano Farris, Tiziana Silvetti, Luca Merlini, Milena Brasca, Rita Grandori, Yves M Galante
We describe aerogels obtained by laccase/TEMPO-oxidation and lyophilization of galactomannans (GM) from fenugreek, sesbania and guar. Enzymatic oxidation of GM in aqueous solution caused viscosity increase up to fifteen-fold, generating structured, elastic, stable hydrogels, presumably due to establishment of hemiacetalic bonds between newly formed carbonyl groups and free hydroxyl groups. Upon lyophilization, water-insoluble aerogels were obtained, whose mechanical properties and porosity were investigated...
February 20, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28012066/effects-of-pre-germinated-fenugreek-seeds-inclusion-in-low-fiber-diets-on-post-weaned-rabbits-health-status-growth-performances-carcass-characteristics-and-meat-chemical-composition
#19
Sabah Mabrouki, Raja Chalghoumi, Hedi Abdouli
Newly weaned rabbits frequently suffer from digestive disorders particularly when fed low-fiber diets. Fenugreek seeds are rich in dietary fiber and would be suited to moderate such disorders. This study investigated the effect of pre-germinated fenugreek seeds (PGFS) on rabbits' health, digestibility, growth performance, and carcass parameters. Fourteen weaned rabbits were fed one of the following diets: (1) low fiber as negative control (NC), (2) low fiber containing 5% PGFS (F5), (3) low fiber containing 10% PGFS (F10), and (4) adequate fiber as positive control (PC)...
March 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/27999511/a-review-of-herbal-and-pharmaceutical-galactagogues-for-breast-feeding
#20
REVIEW
Alessandra N Bazzano, Rebecca Hofer, Shelley Thibeau, Veronica Gillispie, Marni Jacobs, Katherine P Theall
BACKGROUND: Therapeutic approaches to addressing insufficient lactation are available but remain poorly understood. Current trends in maternal health, such as increasing rates of obesity, delayed age at childbearing, and high rates of cesarean section, may be associated with physiological challenges for lactation that cannot be managed by counseling alone. Women who have not had success with counseling alone, including adoptive mothers seeking to induce lactation, may use galactagogues (pharmaceutical and herbal compounds used to increase lactation)...
2016: Ochsner Journal
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