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https://www.readbyqxmd.com/read/29769766/fenugreek-diabetes-and-periodontal-disease-a-cross-link-of-sorts
#1
Gopalakrishnan Sundaram, Theyagarajan Ramakrishnan, Harinath Parthasarathy, Manoj Raja, Samuel Raj
Aims: The aim of this study was to observe the sequelae of fenugreek adjunctive to nonsurgical periodontal therapy and its comparison to a group treated with scaling and root planing (SRP) and metformin alone by assessing their respective effects on periodontal parameters, glycemic status, and serum lipid levels. Materials and Methods: The study comprised eighty patients who were further divided into two groups. Each group consisted of 40 patients. Group 1 consisted of uncontrolled noninsulin-dependent diabetes mellitus (NIDDM) patients with chronic generalized periodontitis, who received SRP and treatment with metformin...
March 2018: Journal of Indian Society of Periodontology
https://www.readbyqxmd.com/read/29749534/comparative-whole-genome-transcriptome-analysis-and-fenugreek-leaf-extract-modulation-on-cadmium%C3%A2-induced-toxicity-in-liver-cells
#2
Caroline Odewumi, Lekan M Latinwo, Roy Leonard Lyles, Veera L D Badisa, Cobb-Abdullah Ahkinyala, Marijo Kent-First
Cadmium (Cd), an economically valuable metal, is widely used in various industrial processes. Although it is of economic value, it is hazardous to human health. Cd accumulates in vital organs where it causes various diseases. Natural compounds with chelating or antioxidant properties have been tested to reduce the toxic effect of Cd. The anti‑oxidant, anti‑diabetic and hypocholesterolemic properties of fenugreek (Trigonella foenum-graecum) leaves make it a candidate for investigation as protective agent against Cd‑induced toxicity...
May 10, 2018: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29743896/investigating-the-effectiveness-of-the-trigonella-foenum-graecum-l-fenugreek-seeds-in-mild-asthma-a-randomized-controlled-trial
#3
Majid Emtiazy, Laleh Oveidzadeh, Minoo Habibi, Leila Molaeipour, Daryush Talei, Zahra Jafari, Mahmoud Parvin, Mohammad Kamalinejad
Background: Asthma is one of the important chronic diseases. The asthma prevalence is increasing in last decades. Despite the presence of good controller drugs like corticosteroids, about 60% of asthmatic patients use alternative medicine. This study was done to determine the effectiveness of Tregonella foenum graceum (fenugreek) seeds in mild asthma. Methods: It is a double blind trial with placebo effect. One of the ancient prescriptions from Persian Medicine was selected...
2018: Allergy, Asthma, and Clinical Immunology
https://www.readbyqxmd.com/read/29673957/carboxymethyl-fenugreek-gum-rheological-characterization-and-as-a-novel-binder-for-silicon-anode-of-lithium-ion-batteries
#4
Liewei Qiu, Yiding Shen, Huabo Fan, Xiaowu Yang, Chen Wang
The rheology of carboxymethyl fenugreek gum (CFG) is characterized and applied it as a binder for the silicon anode of lithium-ion batteries (LIBs). First, a series of carboxymethyl fenugreek gum (namely CFG-1, CFG-2 and CFG-3) was prepared and characterized by Fourier transform infrared spectrophotometer and hydrogen nuclear magnetic resonance spectrometry studies. In rheological measurements, the CFG solutions show higher flowability, weaker viscoelastic behavior and better thixotropy than that of fenugreek gum (FG) solution...
April 16, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29666544/efficiency-of-selected-food-ingredients-on-protein-efficiency-ratio-glycemic-index-and-in-vitro-digestive-properties
#5
M B Anusha, Naveen Shivanna, G Phani Kumar, K R Anilakumar
The human body on exposure to high-altitude, undergoes many physiological challenges. The cardiopulmonary reserves are favoured against the digestive system. Hence, the efficiency of digestion is compromised to a great extent, which leads to anorexia, hypophagia, epigastralgia, dyspepsia, nausea, and peptic ulcers. The present study was focused on in vitro digestive influence of selected food ingredients viz. cardamom, carom, cumin, coriander, fennel, fenugreek, ginger, pepper, star anise, turmeric, papaya, orange, pineapple, liquorice, valerian, and tarragon on the activities of digestive enzymes of rat pancreas, duodenum, and small intestine...
May 2018: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29621421/role-of-bulk-and-nanosized-sio-2-to-overcome-salt-stress-during-fenugreek-germination-trigonella-foenum-graceum-l
#6
Reihane Ivani, Seyed Hossein Sanaei Nejad, Bijan Ghahraman, Ali Reza Astaraei, Hassan Feizi
The effects of bulk and Nanosized SiO2 on seed germination and seedling growth indices of fenugreek under salinity stress were studied in the College of Agriculture, Ferdowsi University of Mashhad, Iran, in 2013. The experimental treatments included four levels of salinity stress (0, 50, 100 and 150 mM), two concentrations of bulk (50 and 100 ppm), two concentrations of nanosized SiO2 (50 and 100 ppm), and control (without any SiO2 types). Seedling growth attributes significantly improved when bulk and nanosized SiO2 concentrations applied singly or with different levels of salt stress...
April 5, 2018: Plant Signaling & Behavior
https://www.readbyqxmd.com/read/29577753/purification-of-the-total-steroidal-saponins-from-fenugreek-seeds-trigonella-foenum-graecum-l-using-aqueous-two-phase-system-and-determination-of-diosgenin-content-using-micellar-electrokinetic-chromatography-method
#7
Na Wang, Famei He, Wenliang Li, Xu Fang, Hailing Li
The total steroidal saponins, particularly its major steroidal sapogenin (diosgenin), are the main active principles of fenugreek seed extract. In this study, an ethanol-salt aqueous two-phase system (ATPS) was explored for the purification of the total steroidal saponins, and the process conditions were optimized by response surface methodology (RSM). Under the optimized conditions, the RSM predicted recovery of the total steroidal saponins in the top phase of ATPS was 97.9%, which agreed with the average experimental recovery (98...
March 26, 2018: Natural Product Research
https://www.readbyqxmd.com/read/29556428/improving-changes-in-physical-sensory-and-texture-properties-of-cake-supplemented-with-purified-amylase-from-fenugreek-trigonella-foenum-graecum-seeds
#8
Bassem Khemakhem, Slim Smaoui, Hanen El Abed, Imen Fendri, Hajer Hammami, Mohamed Ali Ayadi
Three different concentrations of a purified maltogenic amylase (FSA) from fenugreek ( Trigonella foenum graecum ) seeds were incorporated into the cake formulation. The addition of FSA at 0.003, 0.005 and 0.01 U/g of cake increased the loaf volume, the number of holes (gas cells), and water absorption. Textural study revealed an improvement of the cake quality, resulting in the decrease of hardness and the increase of cohesion. Environmental scanning electron microscopy was performed on different cakes to evaluate the influence of amylase activity on microstructure...
March 2018: 3 Biotech
https://www.readbyqxmd.com/read/29543544/abundant-production-of-exopolysaccharide-by-eaec-strains-enhances-the-formation-of-bacterial-biofilms-in-contaminated-sprouts
#9
Quintin Borgersen, David T Bolick, Glynis L Kolling, Matthew Aijuka, Fernando Ruiz-Perez, Richard L Guerrant, James P Nataro, Araceli E Santiago
Enteroaggregative E. coli (EAEC) is associated with food-borne outbreaks of diarrhea and growth faltering among children in developing countries. A Shiga toxin-producing EAEC strain of serotype O104:H4 strain caused one of the largest outbreaks of a food-borne infection in Europe in 2011. The outbreak was traced to contaminated fenugreek sprouts, yet the mechanisms whereby such persistent contamination of sprouts could have occurred are not clear. We found that under ambient conditions of temperature and in minimal media, pathogenic Shiga toxin-producing EAEC O104:H4 227-11 and non-Shiga toxin-producing 042 strains both produce high levels of exopolysaccharide structures (EPS) that are released to the external milieu...
March 15, 2018: Gut Microbes
https://www.readbyqxmd.com/read/29534453/fenugreek-trigonella-foenum-graecum-seed-flour-and-diosgenin-preserve-endothelium-dependent-arterial-relaxation-in-a-rat-model-of-early-stage-metabolic-syndrome
#10
Katalin Szabó, Rudolf Gesztelyi, Nóra Lampé, Rita Kiss, Judit Remenyik, Georgina Pesti-Asbóth, Dániel Priksz, Zoltán Szilvássy, Béla Juhász
Fenugreek is a common herb possessing several bioactive components including diosgenin. Here, dietary fenugreek seed flour and diosgenin were evaluated on a model of endothelium-dependent vasorelaxation by abdominal aortas isolated from rats receiving high-fat, high-sugar diet (HFHSD). 60 male Wistar rats were randomized into six groups: (i) negative control getting conventional rat feed regimen; (ii) positive control receiving HFHSD; (iii) a test group fed 2 g/kg bw/day fenugreek seed flour (containing 10 mg/kg bw/day diosgenin) + HFHSD; (iv) three test groups fed 1, 10 and 50 mg/kg bw/day diosgenin + HFHSD...
March 10, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29530808/biogenic-synthesis-of-copper-nanoparticles-by-natural-polysaccharides-and-pleurotus-ostreatus-fermented-fenugreek-using-gamma-rays-with-antioxidant-and-antimicrobial-potential-towards-some-wound-pathogens
#11
Ahmed I El-Batal, Nawal E Al-Hazmi, Farag M Mosallam, Gharieb S El-Sayyad
Mono-dispersed copper nanoparticles (CuNPs) were constructed using cheap polysaccharides (citrus pectin, chitosan, and sodium alginate), and by appropriating aqueous fermented fenugreek powder (FFP) under the action of Pleurotus ostreatus (as reducing and preserving means), through the influence of gamma irradiation. The created CuNPs are described by UV-Vis. spectroscopy TEM, DLS, XRD, and FT-IR. XRD study of the CuNPs confirmed the generation of metallic CuNPs. The nucleation and the production mechanism of CuNPs are moreover explained...
March 9, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29526086/flavonoid-glycosides-from-fenugreek-seeds-regulate-glycolipid-metabolism-by-improving-mitochondrial-function-in-3t3-l1-adipocytes-in-vitro
#12
Guangxiang Luan, Yuwei Wang, Zhenhua Wang, Wenna Zhou, Na Hu, Gang Li, Honglun Wang
Fenugreek is a well known annual herb widely used in both medicine and food. Four flavonoid glycosides have been separated from fenugreek seeds in our previous study. In this study, the effects of the four flavonoid glycosides on regulating glycolipid metabolism and improving mitochondrial function were investigated. Isoorientin showed a very significant activity among these flavonoid glycosides. First, isoorientin decreased the accumulation of lipid droplets in 3T3-L1 preadipocytes by reducing the expression of adipokines including PPARγ, C/EBPα, and FAS...
March 28, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29518003/insulin-sensitizer-effects-of-fenugreek-seeds-in-parallel-with-changes-in-plasma-mch-levels-in-healthy-volunteers
#13
Rita Kiss, Katalin Szabó, Rudolf Gesztelyi, Sándor Somodi, Péter Kovács, Zoltán Szabó, József Németh, Dániel Priksz, Andrea Kurucz, Béla Juhász, Zoltán Szilvássy
In developed, developing and low-income countries alike, type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases, the severity of which is substantially a consequence of multiple organ complications that occur due to long-term progression of the disease before diagnosis and treatment. Despite enormous investment into the characterization of the disease, its long-term management remains problematic, with those afflicted enduring significant degradation in quality-of-life. Current research efforts into the etiology and pathogenesis of T2DM, are focused on defining aberrations in cellular physiology that result in development of insulin resistance and strategies for increasing insulin sensitivity, along with downstream effects on T2DM pathogenesis...
March 8, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29512786/dioscin-prevents-lps%C3%A2-induced-acute-lung-injury-through-inhibiting-the-tlr4-myd88-signaling-pathway-via-upregulation-of-hsp70
#14
Huiqing Zeng, Lijuan Yang, Xiaobin Zhang, Yan Chen, Jianghang Cai
Dioscin, as a type of important natural steroidal saponin, has widespread sources, primarily from the fenugreek plant, which is an important raw material in the production of synthetic steroid hormone drugs. Dioscin has anti‑tumor, anti‑inflammatory, antioxidant and other significant pharmacological effects with high medicinal value. The present work aimed to research the protective effect and underlying mechanisms by which dioscin prevents acute lung injury (ALI). Mice were injected with 5 mg/kg LPS to induce lung injury...
May 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29485633/effects-of-fermented-ginger-rhizome-zingiber-officinale-and-fenu-greek-trigonella-foenum-graceum-supplements-on-oxidative-stress-and-lipid-peroxidation-biomarkers-in-poloxamer-407-induced-hyperlipidemic-wistar-rats
#15
Y Tanko, A Kabiru, A Abdulrasak, K A Mohammed, A I Salisu, A Jimoh, N M Gidado, N M Sada
This research was aimed at investigating the Effects of Fermented Ginger Rhizome (Zingiber officinale) and Fenu Greek (Trigonella foenum-graceum) on Oxidative stress and Lipid Peroxidation Biomarkers in Poloxamer 407Induced-Hyperlipidemic Wistar Rats. Hyperlipidaemia was induced with poloxamer P407 (1.5 g/kg   b.w. i.p.) The Animals were grouped into six of five animals each group. Group 1 normal control, Group 2 served as the hyperlipidemic control, Group 3 administered 0.26 g/kg cholestyramine, Group 4 fed on Fenugreek 25% supplement...
December 30, 2017: Nigerian Journal of Physiological Sciences: Official Publication of the Physiological Society of Nigeria
https://www.readbyqxmd.com/read/29462748/dietary-administration-effects-of-fenugreek-seeds-on-skin-mucosal-antioxidant-and-immunity-status-of-gilthead-seabream-sparus-aurata-l
#16
F A Guardiola, A Bahi, A M Jiménez-Monreal, M Martínez-Tomé, M A Murcia, M A Esteban
Improving fish defense through the preventive administration of immunostimulants has an important role in controlling the outbreak of the disease in aquaculture. As a continuity of our previous studies, this paper describes the effects of dietary fenugreek (Trigonella foenum graecum) seeds on the skin mucosal antioxidant status and immune response of gilthead seabream (Sparus aurata L.). Fish were fed with four experimental diets: one a basal diet (control) and three diets with powdered fenugreek seeds incorporated in the fish feed at 1%, 5%, and 10%...
April 2018: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29453912/hptlc-determination-of-diosgenin-in-fenugreek-seeds
#17
Barbara Król-Kogus, Khenifi Mohammed Lamine, Piotr Migas, Messaoud Boudjeniba, Mirosława Krauze-Baranowska
A new HPTLC-densitometric method for diosgenin determination in fenugreek seeds was established after optimization of the conditions for efficient saponin extraction and acid hydrolysis. Several procedures were tested, the best of which was a three-step Soxhlet extraction, followed by hydrolysis of the obtained methanolic extract with 2 mol L-1 H2SO4. Best diosgenin separation from other hydrolysis products was obtained on HPTLC Si60F254 plates u sing a mixture of n-heptane/ethyl acetate (7:3, V/V) and modified anisaldehyde as a spraying reagent...
March 1, 2018: Acta Pharmaceutica
https://www.readbyqxmd.com/read/29411062/aerogel-from-chemo-enzymatically-oxidized-fenugreek-gum-an-innovative-delivery-system-of-isothiazolinones-biocides
#18
Tiziana Silvetti, Luca Merlini, Milena Brasca, Yves M Galante
Aerogels of chemo-enzymatically oxidized, lyophilized fenugreek gum (EOLFG) were evaluated as "delivery system" (DS) of the microbiocide mix 5-chloro-2-methyl-4-isothiazolin-3-one (CIT) and 2-methyl-4-isothiazolin-3-one (MIT). These biocides have a broad activity spectrum and a low MIC (minimal inhibitory concentration) in the ppm range. They are approved under the EU Biocidal Product Directive for various applications, including cosmetics, are classified as skin sensitizers, and are under increasing scrutiny to limit or eliminate their use...
March 2018: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/29403626/a-review-of-effective-herbal-medicines-in-controlling-menopausal-symptoms
#19
REVIEW
Rahele Kargozar, Hoda Azizi, Roshanak Salari
Background: Acute menopausal syndrome especially hot flashes, is one of the most common gynecological problems during menopause. Due to the side effects of hormone therapy, herbal and complementary medicines are always of immense interest to people in the treatment and management of the symptoms and complications of menopause. Objective: The aim of this study was to investigate the mechanisms and effects of medicinal plants employed in the treatment of menopausal symptoms...
November 2017: Electronic Physician
https://www.readbyqxmd.com/read/29337247/effects-of-dietary-administration-of-fenugreek-seeds-on-metabolic-parameters-and-immune-status-of-gilthead-seabream-sparus-aurata-l
#20
F A Guardiola, A Bahi, M A Esteban
Medical plants could be used as a prophylactic method in aquaculture because they are considered safe and so very promising alternatives to the use of chemicals. The aim of the present work was to examine the effects of dietary fenugreek (Trigonella foenum graecum) seeds administered for 8 weeks on the metabolic and immune status of gilthead seabream (Sparus aurata L.). Four experimental groups were designated: one receiving a basal diet (control) and three fed powdered fenugreek seeds incorporated in the fish feed at 1%, 5% and 10%...
March 2018: Fish & Shellfish Immunology
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