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plant-based diet

Pankajini Mallick, Pranav Shah, Michael M Ittmann, Meghna Trivedi, Ming Hu, Song Gao, Romi Ghose
Irinotecan is highly effective in the treatment of metastatic colorectal cancer as well as many other cancers. However, irinotecan is known to cause severe diarrhea, which pose significant problems in patients undergoing irinotecan based chemotherapy. Dietary and herbal components have shown promise in improving gastrointestinal health. Therefore, we compared the effect of grain-based chow diet containing phytoestrogens and corn/alfalfa as fat source to purified diets containing either animal-derived fat source (lard) or plant-derived fat source (soybean oil) on irinotecan-induced toxicities in mice...
June 15, 2018: Chemico-biological Interactions
Marie-Pierre St-Onge, Allison Crawford, Brooke Aggarwal
Purpose of review: The goal of this review is to evaluate recent research related to the effects of plant-based diets on sleep patterns. We discuss plausible mechanisms for the link between plant-based diets and sleep, and provide suggestions for future research in this area. Recent findings: Short sleep duration and poor sleep quality have been shown to negatively affect individual dietary habits, through enhanced appetite, increased overall caloric intake, as well as lower diet quality...
March 2018: Current Sleep Medicine Reports
Gabriele Romano, Serena Reggi, Barbara Kutryb-Zajac, Amanda Facoetti, Elisa Chisci, Mariateresa Pettinato, Maria Rita Giuffrè, Federica Vecchio, Silvia Leoni, Marco De Giorgi, Federica Avezza, Massimiliano Cadamuro, Luca Crippa, Biagio Eugenio Leone, Marialuisa Lavitrano, Ilaria Rivolta, Donatella Barisani, Ryszard Tomasz Smolenski, Roberto Giovannoni
BACKGROUND: Atherosclerosis is a slowly progressing, chronic multifactorial disease characterized by the accumulation of lipids, inflammatory cells, and fibrous tissue that drives to the formation of asymmetric focal thickenings in the tunica intima of large and mid-sized arteries. Despite the high therapeutic potential of ApoA-1 proteins, the purification and delivery into the disordered organisms of these drugs is still limited by low efficiency in these processes. METHODS AND RESULTS: We report here a novel production and delivery system of anti-atherogenic APOA-1Milano muteins (APOA-1M) by means of genetically modified rice plants...
June 11, 2018: International Journal of Cardiology
Judilee C Marrow, Sara Hallager, Samantha J Sander, William Sander, Rhea Hanselmann, Suzan Murray
  The kori bustard ( Ardeotis kori) is one of the largest extant flighted birds and is displayed in zoos primarily in North America and Europe. In captivity, kori bustard diets are primarily based on animal proteins, whereas in the wild these birds eat a wide variety of plants, insects, and small vertebrate prey. The purpose of this study was to compare circulating iron, total iron binding capacity, and percent transferrin saturation levels in apparently healthy wild and captive kori bustards. Adult captive kori bustards had slightly higher percent transferrin saturation levels than juvenile captive birds, although this finding was not statistically significant...
June 2018: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
Sören Meyer, Mariya Markova, Gabriele Pohl, Talke A Marschall, Olga Pivovarova, Andreas F H Pfeiffer, Tanja Schwerdtle
Multi-element determination in human samples is very challenging. Especially in human intervention studies sample volumes are often limited to a few microliters and due to the high number of samples a high-throughput is indispensable. Here, we present a state-of-the-art ICP-MS/MS-based method for the analysis of essential (trace) elements, namely Mg, Ca, Fe, Cu, Zn, Mo, Se and I, as well as food-relevant toxic elements such as As and Cd. The developed method was validated regarding linearity of the calibration curves, method LODs and LOQs, selectivity and trueness as well as precision...
September 2018: Journal of Trace Elements in Medicine and Biology
Shilpa N Bhupathiraju, Marta Guasch-Ferré, Meghana D Gadgil, Christopher B Newgard, James R Bain, Michael J Muehlbauer, Olga R Ilkayeva, Denise M Scholtens, Frank B Hu, Alka M Kanaya, Namratha R Kandula
Background: Recent studies, primarily in non-Hispanic whites, suggest that dietary patterns have distinct metabolomic signatures that may influence disease risk. However, evidence in South Asians, a group with unique dietary patterns and a high prevalence of cardiometabolic risk, is lacking. Objective: We investigated the metabolomic profiles associated with 2 distinct dietary patterns among a sample of Asian Indians living in the United States. We also examined the cross-sectional associations between metabolomic profiles and cardiometabolic risk markers...
June 10, 2018: Journal of Nutrition
Conor P Kerley
Evidence supporting the role of nutrition in heart failure (HF) incidence and severity is growing. A comprehensive search of online databases was conducted using relevant keywords to identify human studies including diet and HF. Several plant-based diets have consistently been associated with decreased HF incidence and severity, notably the Dietary Approaches to Stop Hypertension (DASH) and Mediterranean diets. Several other plant-based dietary patterns, including low-fat diets and the rice diet, also show promise...
May 2018: Cardiac failure review
Adam van Casteren, Peter W Lucas, David S Strait, Shaji Michael, Nick Bierwisch, Norbert Schwarzer, Khaled J Al-Fadhalah, Abdulwahab S Almusallam, Lidia A Thai, Sreeja Saji, Ali Shekeban, Michael V Swain
Mammalian tooth wear research reveals contrasting patterns seemingly linked to diet: irregularly pitted enamel surfaces, possibly from consuming hard seeds, versus roughly aligned linearly grooved surfaces, associated with eating tough leaves. These patterns are important for assigning diet to fossils, including hominins. However, experiments establishing conditions necessary for such damage challenge this paradigm. Lucas et al . (Lucas et al . 2013 J. R. Soc. Interface 10 , 20120923. (doi:10.1098/rsif.2012...
May 2018: Royal Society Open Science
Yanling Wang, Elizabeth H Jeffery, Michael J Miller, Matthew A Wallig, Yuanfeng Wu
Dietary broccoli is anti-inflammatory. Past studies have typically investigated raw broccoli, even though most consumers prefer cooked broccoli, where the plant myrosinase is inactivated by heat, resulting in failure of formation of the anti-inflammatory bioactive compound sulforaphane (SF). This study compareed efficacy of lightly cooked broccoli (CB) containing greatly diminished myrosinase activity, with raw broccoli (RB), in mitigating colitis in dextran sulfate sodium (DSS)-treated mice. Male C57BL/6 mice were fed for two weeks on a 10% RB, 10% CB or control diet, all based on the AIN-93M diet...
June 8, 2018: Nutrients
Agustin Ramiro Miranda, Maria Cecilia Cittadini, Claudia Albrecht, Elio Andrés Soria
Polyphenols provide by diet may act as antioxidant in the Central Nervous System and exert a protective effect on metabolic diseases. The aim of this study was to establish tea extract effects on oxidative status and murine overweight in accordance with polyphenolic availability in different encephalic regions. METHODS: Balb/c mice (female, n>3) with overweight received for 15 days 100 mg/Kg/d of extract from Lantana grisebachii, Aspidosperma quebracho-blanco, or Ilex paraguariensis extracts and control group (received water without extract)...
September 8, 2017: Revista de la Facultad de Ciencias Médicas
Tracy Severson, Penny M Kris-Etherton, Jennifer G Robinson, John R Guyton
This roundtable discussion on dietary fats was inspired by a recent Presidential Advisory from the American Heart Association giving recommendations about dietary fats for prevention of atherosclerotic cardiovascular disease. The Advisory clarifies a long-held position that saturated fat should be reduced in the American diet. New studies and meta-analyses have questioned the adverse role of saturated fat. The Advisory adds a crucial clarification based primarily on 4 randomized controlled diet trials, each conducted over 4 to 8 years during the 1960s extending to the 1970s...
May 2018: Journal of Clinical Lipidology
Fredrick J Lee, Kayla I Miller, James B McKinlay, Irene L G Newton
The honey bee worker gut hosts a community of bacteria that comprises 8-10 core bacterial species, along with a set of more transient environmental microbes. Collectively, these microbes break down and ferment saccharides present in the host's diet, based on analyses of metagenomes, and metatranscriptomes from this environment. As part of this metabolism, the bacteria produce short-chain fatty acids that may serve as a food source for the host bee, stimulating biological processes that may contribute to host weight gain...
June 6, 2018: FEMS Microbiology Ecology
Guillem Estruch, Ana Tomás-Vidal, Asmaa M El Nokrashy, Raquel Monge-Ortiz, Sergio Godoy-Olmos, Miguel Jover Cerdá, Silvia Martínez-Llorens
The search for new sustainable aquafeeds for the species with greater economic importance, such as the gilthead sea bream in Europe, is one of the main challenges in the aquaculture sector. The present work tested fishmeal replacement by a mixture of plant meals at different levels, as well as the use of marine by-products with attractant properties and high-quality protein in high plant protein diets. In order to do that, effects on growth and biometric parameters, digestibility, amino acid retention, excreted ammonia and proteases and amylase activity were assessed, using six different diets: FM100 (100% of protein provided by fishmeal), FM50 (50% of replacement), FM25 (75% of replacement) and FM0 (100% of replacement), but also FM25+ (75% of replacement and 15% of squid and krill meal inclusion), and FM0+ (100% of replacement and 15% of squid and krill meal inclusion)...
June 7, 2018: Archives of Animal Nutrition
G Juckel, K Hoffmann
Ayurveda is a traditional Indian system of medicine that is more than 3000 years old, consisting mostly of a specific diet, oily infusions mainly in the area of the head, enemas, medicinal plants and yoga. It is based on a naturopathic and anthropological belief in association with the hinduistic religion. Ayurveda has been practiced very successfully in India but so far it has only been insufficiently appreciated by western medicine, especially psychiatry. An exception is Scharfetter from Zürich who wrote a review article on this topic in 1976...
June 6, 2018: Der Nervenarzt
Daniele Lettieri-Barbato, Katia Aquilano
The standard cancer treatments include chemotherapy, radiotherapy, or their combination, which are generally associated with a multitude of side effects ranging from discomfort to the development of secondary tumors and severe toxicity to multiple systems including immune system. Mounting evidence has highlighted that the fine-tuning of nutrients may selectively sensitize cancer cells to conventional cancer therapies, while simultaneously protecting normal cells from their side effects. Nutrient modulation through diet also improves cancer immunesurveillance in a way that severe immunosuppression could be avoided or even the immune response or immune-based cancer therapies be potentiated also through patient microbiota remodeling...
2018: Frontiers in Oncology
Mari C López-Pérez, Fabián Pérez-Labrada, Lino J Ramírez-Pérez, Antonio Juárez-Maldonado, América B Morales-Díaz, Susana González-Morales, Luis R García-Dávila, Jesús García-Mata, Adalberto Benavides-Mendoza
Silicon is an essential nutrient for humans, additionally is beneficial for terrestrial plants. In plants Si enhances tolerance to different types of stress; in humans, it improves the metabolism and increases the strength of skeletal and connective tissues as well as of the immune system. Most of the Si intake of humans come from edible plants creating a double benefit: first, because the absorption of Si increases the antioxidants and other phytochemicals in plants, thereby increasing its functional value, and second because the higher concentration of Si in plants increases intake in human consumers...
2018: Frontiers in Plant Science
Izaskun Garcia-Mantrana, Marta Selma-Royo, Cristina Alcantara, María C Collado
There is increasing evidence for the interaction between gut microbiome, diet, and health. It is known that dysbiosis is related to disease and that most of the times this imbalances in gut microbial populations can be promoted through diet. Western dietary habits, which are characterized by high intakes of calories, animal proteins, saturated fats, and simple sugars have been linked with higher risk of obesity, diabetes, cancer, and cardiovascular disease. However, little is known about the impact of dietary patterns, dietary components, and nutrients on gut microbiota in healthy people...
2018: Frontiers in Microbiology
Huan Li, Jiapeng Qu, Tongtong Li, Stephan Wirth, Yanming Zhang, Xinquan Zhao, Xiangzhen Li
The gut microbiota in mammals plays a key role in host metabolism and adaptation. However, relatively little is known regarding to how the animals adapts to extreme environments through regulating gut microbial diversity and function. Here, we investigated the diet, gut microbiota, short-chain fatty acid (SCFA) profiles, and cellulolytic activity from two common pika (Ochotona spp.) species in China, including Plateau pika (Ochotona curzoniae) from the Qinghai-Tibet Plateau and Daurian pika (Ochotona daurica) from the Inner Mongolia Grassland...
June 3, 2018: Applied Microbiology and Biotechnology
Marina Boix-Castejón, María Herranz-López, Alberto Pérez Gago, Mariló Olivares-Vicente, Nuria Caturla, Enrique Roche, Vicente Micol
TRIAL DESIGN: Plant-derived polyphenols have shown potential to alleviate obesity-related pathologies by a multi-targeted mechanism in animal models and human intervention studies. A dietary supplement based on a combination of Lippia citriodora (LC) and Hibiscus sabdariffa (HS) polyphenolic extracts was assayed in a double blind and placebo-controlled intervention study with 54 overweight subjects. METHODS: Blood pressure, body weight, height, triceps, biceps and abdominal skinfold thickness, and arm and abdominal circumferences were taken at the baseline, 30 and 60 days of the intervention period...
June 4, 2018: Food & Function
Laura Chiavaroli, Stephanie K Nishi, Tauseef A Khan, Catherine R Braunstein, Andrea J Glenn, Sonia Blanco Mejia, Dario Rahelić, Hana Kahleová, Jordi Salas-Salvadó, David J A Jenkins, Cyril W C Kendall, John L Sievenpiper
BACKGROUND: The evidence for the Portfolio dietary pattern, a plant-based dietary pattern that combines recognized cholesterol-lowering foods (nuts, plant protein, viscous fibre, plant sterols), has not been summarized. OBJECTIVE: To update the European Association for the Study of Diabetes clinical practice guidelines for nutrition therapy, we conducted a systematic review and meta-analysis of controlled trials using GRADE of the effect of the Portfolio dietary pattern on the primary therapeutic lipid target for cardiovascular disease prevention, low-density lipoprotein cholesterol (LDL-C), and other established cardiometabolic risk factors...
May 25, 2018: Progress in Cardiovascular Diseases
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