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Hyperprolactinemia

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https://www.readbyqxmd.com/read/29140989/joint-approach-based-on-clinical-and-imaging-features-to-distinguish-non-neoplastic-from-neoplastic-pituitary-stalk-lesions
#1
Ji Ye Lee, Ji Eun Park, Woo Hyun Shim, Seung Chai Jung, Choong Gon Choi, Sang Joon Kim, Jeong Hoon Kim, Ho Sung Kim
PURPOSE: Distinguishing non-neoplastic pituitary stalk lesions (non-NPSLs) from neoplastic pituitary stalk lesions (NPSLs) is a major concern in guiding treatment for a thickened pituitary stalk. Our study aimed to aid provide preoperative diagnostic assistance by combining clinical and magnetic resonance imaging (MRI) findings to distinguish non-NPSLs from NPSLs. MATERIALS AND METHODS: We recruited 158 patients with thickened pituitary stalk lesions visible on MRI...
2017: PloS One
https://www.readbyqxmd.com/read/29124662/dopamine-agonist-withdrawal-in-hyperprolactinemia-when-and-how
#2
EDITORIAL
Roberto Salvatori
No abstract text is available yet for this article.
November 9, 2017: Endocrine
https://www.readbyqxmd.com/read/29122047/antipsychotic-polypharmacy-in-older-australians
#3
Lisa M Kalisch Ellett, Nicole L Pratt, Mhairi Kerr, Elizabeth E Roughead
BACKGROUND: Antipsychotics are commonly used, and the rate of use is highest, among those aged 65 years or over, where the risk of adverse events is also high. Up to 20% of younger adults use more than one antipsychotic concurrently; however there are few studies on the prevalence of antipsychotic polypharmacy in older people. We aimed to analyze antipsychotic use in elderly Australians, focusing on the prevalence of antipsychotic polypharmacy and the use of medicines to manage adverse events associated with antipsychotics...
November 10, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/29120651/-valvular-heart-disease-in-relation-to-the-treatment-of-hyperprolactinemia-with-dopamine-agonists
#4
Filip Gabalec, Jan Čáp, Jakub Radocha
Adverse effect of dopamine agonists on the heart valves aroused much attention some time ago. Gradually, as data accumulated, the approach to the problem was rationalised and further examinations were only recommended in indicated cases. The paper reviews the current knowledge about the treatment of hyperprolactinemia with dopamine agonists and the risk of valvular disease.Key words: dopamine agonists - ergolines/adverse effects - heart valve diseases - hyperprolactinemia - pituitary neoplasms - prolactinoma...
2017: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/29118523/three-cases-of-hair-loss-analyzed-by-the-point-of-view-of-the-analytical-psychology
#5
Ademir Carvalho Leite Júnior, Tatiele Katzer, Denise Gimenez Ramos
Psychotrichology is the science, which covers the psychosomatics applied to hair problems, i.e., body-psyche phenomena involving scalp and hair disorders. The approaches involving psychotricology are varied and may include psychiatric,[1] psychoanalytical,[23] and those involving knowledge related to analytical psychology.[4] An analysis from the analytical psychology point of view, a theory developed by the physician Carl Gustav Jung, favors a symbolic view to the disease, providing it attributions and meanings that go beyond those related to physical body signs and symptoms only...
October 2017: International Journal of Trichology
https://www.readbyqxmd.com/read/29112461/calcium-and-vitamin-d-supplementation-in-boys-with-risperidone-induced-hyperprolactinemia-a-randomized-placebo-controlled-pilot-study
#6
Chadi A Calarge, James A Mills, Ekhard E Ziegler, Janet A Schlechte
BACKGROUND: The chronic use of antipsychotics has been associated with impaired bone mineralization, partially mediated by hyperprolactinemia. We examined if calcium and vitamin D supplementation promote bone mineral accrual in boys with risperidone-induced hyperprolactinemia. METHODS: Between February 2009 and November 2013, medically healthy, 5- to 17-year-old boys were enrolled in a 36-week double-blind, placebo-controlled study, examining the skeletal effects of supplementation with 1250 mg calcium carbonate and 400 IU of vitamin D3 in risperidone-induced hyperprolactinemia...
November 7, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29061463/presentation-treatment-and-long-term-outcome-of-intrasellar-chordoma-a-pooled-analysis-of-institutional-seer-and-published-data
#7
Abdul-Kareem Ahmed, Hassan Y Dawood, Omar M Arnaout, Edward R Laws, Timothy R Smith
BACKGROUND: Chordoma that occurs primarily in the sella turcica is rare and presents unique treatment challenges. OBJECTIVE: The purpose of this study was to determine common features, treatment approaches and survival characteristics of intrasellar chordoma. METHODS: Institutional databases, the Surveillance, Epidemiology, and End Results (SEER) database, and PubMed/EMBASE were queried for chordoma with a primarily intrasellar component. The SEER database was also queried for adult skull base chordoma...
October 20, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29043560/optimal-timing-of-dopamine-agonist-withdrawal-in-patients-with-hyperprolactinemia-a-systematic-review-and-meta-analysis
#8
Miao Yun Xia, Xiao Hui Lou, Shao Jian Lin, Zhe Bao Wu
PURPOSE: Dopamine agonists (DAs) are recommended as first-line treatment for patients with hyperprolactinemia. Generally, it is accepted that patients with hyperprolactinemia do not need lifelong medication, but the optimal timing for DA withdrawal has not been determined. The aim of this systematic review and meta-analysis is to assess the impact of DA withdrawal on the clinical outcomes of patients with hyperprolactinemia, and to explore possible factors affecting successful DA withdrawal...
October 17, 2017: Endocrine
https://www.readbyqxmd.com/read/29039178/-potential-clinical-application-of-kisspeptin-in-reproductive-endocrinology
#9
Yanling Fu, Yimin Zhu
Gonadotropin-releasing hormone (GnRH) plays an important role in the process of reproduction. Studies have shown that a family of peptides Kisspeptin can act on GnRH-related neurons, stimulating the secretion of GnRH, and activating the hypothalamic-pituitary-gonadal axis. Both animal experiments and clinical studies have shown that exogenous administration of Kisspeptin is able to induce physiological GnRH release in healthy individuals and those with endocrine-disorders, which brings great hope for treatment of reproductive endocrine diseases...
May 25, 2017: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
https://www.readbyqxmd.com/read/29038733/mining-comorbidity-patterns-using-retrospective-analysis-of-big-collection-of-outpatient-records
#10
Svetla Boytcheva, Galia Angelova, Zhivko Angelov, Dimitar Tcharaktchiev
BACKGROUND: Studying comorbidities of disorders is important for detection and prevention. For discovering frequent patterns of diseases we can use retrospective analysis of population data, by filtering events with common properties and similar significance. Most frequent pattern mining methods do not consider contextual information about extracted patterns. Further data mining developments might enable more efficient applications in specific tasks like comorbidities identification. METHODS: We propose a cascade data mining approach for frequent pattern mining enriched with context information, including a new algorithm MIxCO for maximal frequent patterns mining...
December 2017: Health Information Science and Systems
https://www.readbyqxmd.com/read/29019716/subclinical-impairment-of-the-left-ventricular-longitudinal-function-in-patients-with-prolactinomas
#11
Xiao-Bing Jiang, Jing Zhang, Cui-Ling Li, Zhi-Gang Mao, Bin Hu, Zhe Zhu, Yong-Hong Zhu, Hai-Jun Wang
Purpose Hyperprolactinemia has been associated with endothelial dysfunction and a wide range of cardiovascular risk factors, thus it can potentially lead to cardiac dysfunction. The present study was designed to interrogate our hypothesis that hyperprolactinemia can contribute to preclinical impaired left ventricular function. Patients and Methods Thirty-one prolactinoma patients and sixty healthy volunteers were prospectively recruited. Left ventricular function was evaluated using conventional two dimensions and M-mode echocardiography, as well as Doppler tissues imaging (DTI)...
October 11, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28966250/psychiatric-patients-with-antipsychotic-drug-induced-hyperprolactinemia-and-menstruation-disorders
#12
Kenshi Takechi, Yurika Yoshioka, Hitoshi Kawazoe, Mamoru Tanaka, Shingo Takatori, Miwako Kobayashi, Ichiro Matsuoka, Hiroaki Yanagawa, Yoshito Zamami, Masaki Imanishi, Keisuke Ishizawa, Akihiro Tanaka, Hiroaki Araki
Treatment with antipsychotic drugs has been associated with hyperprolactinemia. The same antipsychotic drugs have also been associated with side effects such as menstruation disorders. The aim of this study was to evaluate the prevalence of hyperprolactinemia and menstruation disorders in women undergoing antipsychotic treatment. We performed a retrospective chart review study of psychiatric patients who underwent laboratory testing for serum prolactin (PRL) level between March 2011 and March 2015 in Ehime University Hospital...
2017: Biological & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28946556/the-mechanism-of-selfheal-extract-in-treating-hyperprolactinemia
#13
Suxian Luan, Xiaomei Xu, Meiling Mu, Liangzhi Sun
OBJECTIVE: Selfheal has been used for many years in hyperprolactinemia induced galactorrhea, menstrual disorders, and dysgenesis with satisfactory curative effect. However, its mechanism is still unclear. This study intended to investigate the effect of selfheal extract on hyperprolactinemia in vivo and in vitro, in order to elucidate its mechanism of anti-hyperprolactinemia. PATIENTS AND METHODS: Hyperprolactinemia rat model was established. High dose (28.8 g/(kg⋅d)), middle dose (14...
September 15, 2017: Cancer Biomarkers: Section A of Disease Markers
https://www.readbyqxmd.com/read/28931779/the-efficacy-of-medical-treatment-in-patients-with-acromegaly-in-clinical-practice
#14
Seo Young Lee, Jung Hee Kim, Ji Hyun Lee, Yong Hwy Kim, Hyang Jin Cha, Sang Wan Kim, Sun Ha Paek, Chan Soo Shin
Although somatostatin analogues (SSAs) are recommended as the first-line medical therapy for acromegaly, dopamine agonists (DAs) are also a therapeutic option for treatment. We aimed to assess and compare the efficacies of DAs and SSAs in treating acromegaly in clinical practice. We included 89 patients with acromegaly who took DAs (bromocriptine [BCT], n = 63; cabergoline [CAB], n = 11) or SSAs (n = 15) as a primary medical therapy for more than 3 months in the Seoul National University Hospital. The CAB (45...
September 20, 2017: Endocrine Journal
https://www.readbyqxmd.com/read/28925774/resolution-of-dopamine-agonist-resistant-hyperprolactinemia-by-hysterectomy-a-case-report
#15
Hiroshi Sato, Yuna Asami, Reona Shiro, Miki Yasuda, Saeko Imai, Rie Sakai, Kenji Oida, Kanako Kawaharamura, Nao Taguchi, Takako Suzuki, Masaya Hirose
Prolactin-producing uterine leiomyomas are very rare. Although hyperprolactinemia rapidly improves after removal of such leiomyomas, no preoperative diagnostic test has been established for prolactin-producing uterine leiomyomas. A 45-year-old Japanese woman, gravida 3 para 3, was referred to our hospital for further examination of hyperprolactinemia resistant to a dopamine agonist. A pituitary prolactinoma was undetectable by brain magnetic resonance imaging. A bromocriptine loading test revealed an increased serum prolactin concentration after loading...
September 19, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28924485/hypogonadotropic-hypogonadism-in-human-immunodeficiency-virus-infected-men-uncommonly-low-testosterone-levels
#16
Ana Coelho Gomes, José Maria Aragüés, Sílvia Guerra, Joana Fernandes, Mário Rui Mascarenhas
Hypogonadotropic hypogonadism (HH) is common and occurs prematurely in HIV-infected men. However, HH with very low testosterone has not been described. Three men with normal pubertal development and HIV1 diagnosis at the ages of 22, 34 and 35 years. All complained of decreased libido, anejaculation and erectile dysfunction thirteen years, six months and one year after HIV diagnosis, respectively. Two had depressive syndrome and two were treated with antiretroviral therapy. Laboratory tests revealed isolated HH in all...
2017: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/28904704/-prolactin-secreting-microadenoma-in-menopausal-women
#17
Ines Barka, Emna Dendana, Nesrine Chikhrouhou, Amel Maroufi, Maha Kacem, Molka Chadli, Koussay Ach
Prolactin-secreting adenoma is rare in elderly women. Patient's clinical picture may be confused with that of menopause, making diagnosis sometimes difficult. We report the case of a 57-year old woman with a 2-year history of secondary amenorrhea without hot flushes associated with galactorrhea in order to highlight the peculiarities of prolactin-secreting microadenomas. Physical examination confirmed the diagnosis of galactorrhoea and biology showed hyperprolactinemia at mIU/L, FSH = 15.1 IU/L and LH = 4,1 IU/L...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28889207/antipsychotic-induced-hyperprolactinemia-synthesis-of-world-wide-guidelines-and-integrated-recommendations-for-assessment-management-and-future-research
#18
REVIEW
Jasmin Grigg, Roisin Worsley, Caroline Thew, Caroline Gurvich, Natalie Thomas, Jayashri Kulkarni
RATIONALE: Hyperprolactinemia is a highly prevalent adverse effect of many antipsychotic agents, with potentially serious health consequences. Several guidelines have been developed for the management of this condition; yet, their concordance has not been evaluated. OBJECTIVES: The objectives of this paper were (1) to review current clinical guidelines; (2) to review key systematic evidence for management; and (3) based on our findings, to develop an integrated management recommendation specific to male and female patients who are otherwise clinically stabilised on antipsychotics...
November 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28881537/-the-relationship-between-autoimmune-thyroiditis-and-pregnancy-outcomes-of-patients-with-pcos-following-in-vitro-fertilization-and-embryo-transfer-ivf-et
#19
X F Li, H B Chi, J Qiao
Objective: To investigate the impact of autoimmune thyroiditis (AIT) on pregnancy outcomes in patients with polycystic ovary syndrome (PCOS) following the in vitro fertilization and embryo transfer (IVF-ET) by analyzing their pregnancy outcomes. Methods: The patients undergoing IVF-ET treatment diagnosed with PCOS in Peking University Third Hospital from May 2010 to December 2014 were investigated. According to the anti-thyroid antibodies (TPOAb or TGAb), patients were divided into AIT group and non-AIT group...
September 5, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28880406/incidental-neuronal-intermediate-filament-inclusion-pathology-unexpected-biopsy-findings-in-a-37-year-old-woman-with-epilepsy
#20
Ellen Gelpi, Cristina Carrato, Laia Grau-López, Juan Luis Becerra, Roser Garcia-Armengol, Anna Massuet, Laura Cervera, Jordi Clarimon, Katrin Beyer, Ramiro Álvarez
We present unexpected neuropathological findings in a 37 year old woman who underwent surgery for removal of an epidermoid cyst. A first brain MRI at the age of 27 years (due to hyperprolactinemia) showed a cystic lesion in the right prepontine region involving the cisterna ambiens with supratentorial extension. The lesion remained stable until she was 32 year, when it increased in size causing partial compression of the parahippocampal gyrus, midbrain peduncle and lateral pons (Fig. 1). One year later, the patient started to present weekly seizures in form of partial focal complex seizures...
September 7, 2017: Neuropathology and Applied Neurobiology
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