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https://www.readbyqxmd.com/read/28337138/motor-skill-learning-in-an-insect-inspired-neuro-computational-control-system
#1
Eleonora Arena, Paolo Arena, Roland Strauss, Luca Patané
In nature, insects show impressive adaptation and learning capabilities. The proposed computational model takes inspiration from specific structures of the insect brain: after proposing key hypotheses on the direct involvement of the mushroom bodies (MBs) and on their neural organization, we developed a new architecture for motor learning to be applied in insect-like walking robots. The proposed model is a nonlinear control system based on spiking neurons. MBs are modeled as a nonlinear recurrent spiking neural network (SNN) with novel characteristics, able to memorize time evolutions of key parameters of the neural motor controller, so that existing motor primitives can be improved...
2017: Frontiers in Neurorobotics
https://www.readbyqxmd.com/read/28336909/stair-climbing-test-predicts-postoperative-cardiopulmonary-complications-and-hospital-stay-in-patients-with-non-small-cell-lung-cancer
#2
Jingsi Dong, Yousheng Mao, Jiagen Li, Jie He
BACKGROUND There is currently no reliable method to predict major postoperative cardiopulmonary complications for patients with non-small cell lung cancer (NSCLC). In this study, we hypothesized that exercise oxygen desaturation (EOD) and heart rate change results in a stair-climbing test (SCT) would predict postoperative cardiopulmonary complications for patients with NSCLC. MATERIAL AND METHODS We examined 171 patients (41 females and 130 males) with NSCLC by preoperative SCT from January 2010 to July 2015...
March 24, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28334370/differences-in-climbing-ability-of-cimex-lectularius-and-cimex-hemipterus-hemiptera-cimicidae
#3
Dae-Yun Kim, Johan Billen, Stephen L Doggett, Chow-Yang Lee
The climbing abilities of two bed bug species, Cimex lectularius L. and Cimex hemipterus (F.), were determined by evaluating their escape rates from smooth surface pitfall traps using four commercial bed bug monitors (Verifi Bed Bug Detector, ClimbUp Insect Interceptor, BlackOut Bed Bug Detector, and SenSci Volcano Bed Bug Detector). All detectors were used in the absence of lures or attractants. Unlike C. lectularius, adult C. hemipterus were able to escape from all traps. On the other hand, no or a low number nymphs of both species escaped, depending on the evaluated traps...
March 15, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/28334119/climbing-the-yeast-cell-wall
#4
Enrico Cabib
Here is a life in three countries, with different cultures, different political structures and even different skies. The constant through all these changes is the addiction of the subject of this story to science and laboratory work. Perhaps the tale that unfolds here will show to some beginners in research that persistence, seasoned with a little luck, can bring results and satisfaction in the long run.
February 25, 2017: FEMS Yeast Research
https://www.readbyqxmd.com/read/28326013/molecular-chaperone-calnexin-regulates-the-function-of-drosophila-sodium-channel-paralytic
#5
Xi Xiao, Changyan Chen, Tian-Ming Yu, Jiayao Ou, Menglong Rui, Yuanfen Zhai, Yijing He, Lei Xue, Margaret S Ho
Neuronal activity mediated by voltage-gated channels provides the basis for higher-order behavioral tasks that orchestrate life. Chaperone-mediated regulation, one of the major means to control protein quality and function, is an essential route for controlling channel activity. Here we present evidence that Drosophila ER chaperone Calnexin colocalizes and interacts with the α subunit of sodium channel Paralytic. Co-immunoprecipitation analysis indicates that Calnexin interacts with Paralytic protein variants that contain glycosylation sites Asn313, 325, 343, 1463, and 1482...
2017: Frontiers in Molecular Neuroscience
https://www.readbyqxmd.com/read/28325033/user-intent-prediction-with-a-scaled-conjugate-gradient-trained-artificial-neural-network-for-lower-limb-amputees-using-a-powered-prosthesis
#6
Richard B Woodward, John A Spanias, Levi J Hargrove
Powered lower limb prostheses have the ability to provide greater mobility for amputee patients. Such prostheses often have pre-programmed modes which can allow activities such as climbing stairs and descending ramps, something which many amputees struggle with when using non-powered limbs. Previous literature has shown how pattern classification can allow seamless transitions between modes with a high accuracy and without any user interaction. Although accurate, training and testing each subject with their own dependent data is time consuming...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324764/enhancing-mitofusin-marf-ameliorates-neuromuscular-dysfunction-in-drosophila-models-of-tdp-43-proteinopathies
#7
Bilal Khalil, Marie-Jeanne Cabirol-Pol, Laetitia Miguel, Alexander J Whitworth, Magalie Lecourtois, Jean-Charles Liévens
Transactive response DNA-binding protein 43 kDa (TDP-43) is considered a major pathological protein in amyotrophic lateral sclerosis and frontotemporal lobar degeneration. The precise mechanisms by which TDP-43 dysregulation leads to toxicity in neurons are not fully understood. Using TDP-43-expressing Drosophila, we examined whether mitochondrial dysfunction is a central determinant in TDP-43 pathogenesis. Expression of human wild-type TDP-43 in Drosophila neurons results in abnormally small mitochondria...
February 27, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/28323761/effect-of-land-based-generic-physical-activity-interventions-on-pain-physical-function-and-physical-performance-in-hip-and-knee-osteoarthritis-a-systematic-review-and-meta-analysis
#8
Shanelle Fernandopulle, Meredith Perry, Donald Manlapaz, Prasath Jayakaran
OBJECTIVE: The aim of this study was to evaluate the effects of land-based generic physical activity interventions on pain, physical function, and physical performance in individuals with hip/knee osteoarthritis, when compared with a control group that received no intervention, minimal intervention, or usual care. METHODS: A systematic search for randomized controlled trials on 11 electronic databases (from their inception up until April 30, 2016) identified 27 relevant articles...
March 18, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28321690/quality-of-life-following-sentinel-node-biopsy-for-primary-cutaneous-melanoma-health-economic-implications
#9
Rachael L Morton, Anh Tran, Johan Yusof Vessey, Nick Rowbotham, Julie Winstanley, Kerwin Shannon, Andrew J Spillane, Jonathan Stretch, John F Thompson, Robyn P-M Saw
BACKGROUND: Sentinel node biopsy (SNB) is commonly performed in contemporary melanoma management, however there is a paucity of long-term quality of life (QoL) estimates required for economic evaluation of this treatment. METHODS: A single-center, prospective, cross-sectional study of adults with American Joint Committee on Cancer stage I/II/IIIA melanoma of the limbs, trunk, or neck who had undergone wide excision and SNB, but not complete regional node dissection, was undertaken...
March 20, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28317555/the-cervical-spine-of-australopithecus-sediba
#10
Marc R Meyer, Scott A Williams, Peter Schmid, Steven E Churchill, Lee R Berger
Cervical vertebrae are rare in the early hominin fossil record, presenting a challenge for understanding the evolution of the neck and head carriage in hominin evolution. Here, we examine the cervical vertebrae of Australopithecus sediba, which unlike other South African taxa is known from associated cervical vertebrae. The A. sediba cervical vertebrae exhibit human-like values for wedging, pedicle cross-sectional areas, and articular facet heights, indicating reduced ventral loading relative to African apes...
March 2017: Journal of Human Evolution
https://www.readbyqxmd.com/read/28317552/adaptation-to-suspensory-locomotion-in-australopithecus-sediba
#11
Thomas R Rein, Terry Harrison, Kristian J Carlson, Katerina Harvati
Australopithecus sediba is represented by well-preserved fossilized remains from the locality of Malapa, South Africa. Recent work has shown that the combination of features in the limb skeleton of A. sediba was distinct from that of earlier species of Australopithecus, perhaps indicating that this species moved differently. The bones of the arm and forearm indicate that A. sediba was adapted to suspensory and climbing behaviors. We used a geometric morphometric approach to examine ulnar shape, potentially identifying adaptations to forelimb suspensory locomotion in A...
March 2017: Journal of Human Evolution
https://www.readbyqxmd.com/read/28306154/protein-intake-and-mobility-limitation-in-community-dwelling-older-adults-the-health-abc-study
#12
Denise K Houston, Janet A Tooze, Katelyn Garcia, Marjolein Visser, Susan Rubin, Tamara B Harris, Anne B Newman, Stephen B Kritchevsky
OBJECTIVES: The current Recommended Dietary Allowance (RDA) for protein is based on short-term nitrogen balance studies in young adults and may underestimate the amount needed to optimally preserve physical function in older adults. We examined the association between protein intake and the onset of mobility limitation over 6 years of follow-up in older adults in the Health ABC study. DESIGN: Prospective cohort study. SETTING: Memphis, Tennessee and Pittsburgh, Pennsylvania...
March 17, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28303944/relationships-between-strength-and-endurance-parameters-and-air-depletion-rates-in-professional-firefighters
#13
Stephanie Windisch, Wolfgang Seiberl, Ansgar Schwirtz, Daniel Hahn
The aim of this study was to quantify the physical demands of a simulated firefighting circuit and to establish the relationship between job performance and endurance and strength fitness measurements. On four separate days 41 professional firefighters (39 ± 9 yr, 179.6 ± 2.3 cm, 84.4 ± 9.2 kg, BMI 26.1 ± 2.8 kg/m(2)) performed treadmill testing, fitness testing (strength, balance and flexibility) and a simulated firefighting exercise. The firefighting exercise included ladder climbing (20 m), treadmill walking (200 m), pulling a wire rope hoist (15 times) and crawling an orientation section (50 m)...
March 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28302377/stair-negotiation-as-a-rehabilitation-intervention-for-enhancing-recovery-following-total-hip-and-knee-replacement-surgery
#14
REVIEW
James P Gavin, Tikki Immins, Thomas Wainwright
BACKGROUND: Total hip replacement (THR) and total knee replacement (TKR) are common orthopaedic procedures. However, an optimal programme for post-operative rehabilitation has yet to be established. Stair negotiation is a challenging, habitual task, regularly used as a post-operative functional outcome measure; yet as a physical rehabilitation intervention it appears to be rarely used. AIM: The review purpose was to investigate the effectiveness of stair climbing as a rehabilitation intervention for THR and TKR patients...
October 20, 2016: International Journal of Orthopaedic and Trauma Nursing
https://www.readbyqxmd.com/read/28301444/hemodynamic-and-cardiorespiratory-predictors-of-sport-rock-climbing-performance
#15
Simon Fryer, David Giles, Inmaculada Garrido Palomino, Alejandro de la O Puerta, Vanesa España Romero
Rock climbing performance has been suggested to involve a notable contribution from the aerobic metabolism. Previously it has been shown that forearm oxygenation kinetics can be used to distinguish ability groups and predict red-point sport climbing performance. Currently it is not known if forearm oxygenation kinetics, or a sport specific assessment of cardiorespiratory fitness best predicts sport rock climbing performance. The aim of the study was to determine whether forearm oxidative capacity index, maximal de-oxygenation (Δ score) during a treadwall V[Combining Dot Above]O[SUBSCRIPT TWO]peak test, treadwall V[Combining Dot Above]O[SUBSCRIPT TWO]peak, or running V[Combining Dot Above]O[SUBSCRIPT TWO]max best predicts self-reported sport climbing performance...
March 13, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28300156/superconductivity-in-hfte5-across-weak-to-strong-topological-insulator-transition-induced-via-pressures
#16
Y Liu, Y J Long, L X Zhao, S M Nie, S J Zhang, Y X Weng, M L Jin, W M Li, Q Q Liu, Y W Long, R C Yu, C Z Gu, F Sun, W G Yang, H K Mao, X L Feng, Q Li, W T Zheng, H M Weng, X Dai, Z Fang, G F Chen, C Q Jin
Recently, theoretical studies show that layered HfTe5 is at the boundary of weak &strong topological insulator (TI) and might crossover to a Dirac semimetal state by changing lattice parameters. The topological properties of 3D stacked HfTe5 are expected hence to be sensitive to pressures tuning. Here, we report pressure induced phase evolution in both electronic &crystal structures for HfTe5 with a culmination of pressure induced superconductivity. Our experiments indicated that the temperature for anomaly resistance peak (Tp) due to Lifshitz transition decreases first before climbs up to a maximum with pressure while the Tp minimum corresponds to the transition from a weak TI to strong TI...
March 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28297429/method-and-phantom-to-study-combined-effects-of-in-plane-x-y-and-z-axis-resolution-for-3d-ct-imaging
#17
David Goodenough, Josh Levy, Smari Kristinsson, Jesper Fredriksson, Hildur Olafsdottir, Austin Healy
Increasingly, the advent of multislice CT scanners, volume CT scanners, and total body spiral acquisition modes has led to the use of Multi Planar Reconstruction and 3D datasets. In considering 3D resolution properties of a CT system it is important to note that both the in-plane (x,y) and z-axis (slice thickness) influence the visualization and detection of objects within the scanned volume. This study investigates ways to consider both the in-plane resolution and the z-axis resolution in a single phantom wherein analytic or visualized analysis can yield information on these combined effects...
September 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28296942/co-ingestion-of-carbohydrate-and-whey-protein-increases-fasted-rates-of-muscle-protein-synthesis-immediately-after-resistance-exercise-in-rats
#18
Wanyi Wang, Zhenping Ding, Geoffrey J Solares, Soon-Mi Choi, Bo Wang, Aram Yoon, Roger P Farrar, John L Ivy
The objective of the study was to investigate whether co-ingestion of carbohydrate and protein as compared with protein alone augments muscle protein synthesis (MPS) during early exercise recovery. Two months old rats performed 10 repetitions of ladder climbing with 75% of body weight attached to their tails. Placebo (PLA), whey protein (WP), or whey protein plus carbohydrate (CP) was then given to rats by gavage. An additional group of sedentary rats (SED) was used as controls. Blood samples were collected immediately and at either 1 or 2 h after exercise...
2017: PloS One
https://www.readbyqxmd.com/read/28293172/ethanol-modulates-the-spontaneous-complex-spike-waveform-of-cerebellar-purkinje-cells-recorded-in-vivo-in-mice
#19
Guang-Jian Zhang, Mao-Cheng Wu, Jin-Di Shi, Yin-Hua Xu, Chun-Ping Chu, Song-Biao Cui, De-Lai Qiu
Cerebellar Purkinje cells (PCs) are sensitive to ethanol, but the effect of ethanol on spontaneous complex spike (CS) activity in these cells in vivo is currently unknown. Here, we investigated the effect of ethanol on spontaneous CS activity in PCs in urethane-anesthetized mice using in vivo patch-clamp recordings and pharmacological manipulation. Ethanol (300 mM) induced a decrease in the CS-evoked pause in simple spike (SS) firing and in the amplitude of the afterhyperpolarization (AHP) under current clamp conditions...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28289890/kinematic-analysis-of-stair-climbing-in-rotating-platform-cruciate-retaining-and-posterior-stabilized-mobile-bearing-total-knee-arthroplasties
#20
Koji Murakami, Satoshi Hamai, Ken Okazaki, Satoru Ikebe, Hiroyuki Nakahara, Hidehiko Higaki, Takeshi Shimoto, Hideki Mizu-Uchi, Umito Kuwashima, Yukihide Iwamoto
INTRODUCTION: The aim of our study was to compare and contrast the effects of two types of mobile-bearing total knee arthroplasties (TKA), namely, the cruciate-retaining (CR) and posterior-stabilized (PS) TKAs, on clinical outcomes and in vivo kinematics during stair climbing. MATERIALS AND METHODS: The Press-Fit Condylar Sigma rotating platform was used for both CR and PS TKAs. Patient-reported outcomes were assessed using the 2011 Knee Society Score. Quadriceps muscle strength was evaluated by isokinetic dynamometry...
March 13, 2017: Archives of Orthopaedic and Trauma Surgery
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