Pierrick Godin, Francois P Duhoux, Filomena Mazzeo, Michel Rojas, Emmanuel Bollue, Aline François, Christine Galant, Julien Coulie, Maude Coyette, Audrey Lentini, Yannick Deswisen, Vasiliki Perlepe, Latifa Fellah, Isabelle Leconte, Martine Berlière
Epidemiological studies suggest that around 10% of breast cancers are due to hereditary predisposition. The risk of cancer is exponentially increased in patients harboring BRCA1 or BRCA2 mutations. Cumulative breast cancer risk by age 80 is estimated to 72% for BRCA1 mutation carriers and 69% for BRCA2 . The cumulative risk estimates for developing ovarian cancer by age 80 are 44% for BRCA1 mutation carriers and 17% for BRCA2 . We present here the case of a 59-year-old woman who developed a left breast cancer in 2014 treated by conservative surgery, radiotherapy, and endocrine therapy with letrozole...
January 2022: Case Reports in Oncology