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https://www.readbyqxmd.com/read/28623590/integration-of-genome-wide-tf-binding-and-gene-expression-data-to-characterize-gene-regulatory-networks-in-plant-development
#1
Dijun Chen, Kerstin Kaufmann
Key transcription factors (TFs) controlling the morphogenesis of flowers and leaves have been identified in the model plant Arabidopsis thaliana. Recent genome-wide approaches based on chromatin immunoprecipitation (ChIP) followed by high-throughput DNA sequencing (ChIP-seq) enable systematic identification of genome-wide TF binding sites (TFBSs) of these regulators. Here, we describe a computational pipeline for analyzing ChIP-seq data to identify TFBSs and to characterize gene regulatory networks (GRNs) with applications to the regulatory studies of flower development...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28623001/a-concealed-observational-study-of-infection-control-and-safe-injection-practices-in-jordanian-governmental-hospitals
#2
Omar M Al-Rawajfah, Ahmad Tubaishat
BACKGROUND: The recognized international organizations on infection prevention recommend using an observational method as the gold standard procedure for assessing health care professional's compliance with standard infection control practices. However, observational studies are rarely used in Jordanian infection control studies. This study aimed to evaluate injection practices among nurses working in Jordanian governmental hospitals. METHODS: A cross-sectional concealed observational design is used for this study...
June 13, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28620876/english-orthographic-learning-in-chinese-l1-young-efl-beginners
#3
Yu-Lin Cheng
English orthographic learning, among Chinese-L1 children who were beginning to learn English as a foreign language, was documented when: (1) only visual memory was at their disposal, (2) visual memory and either some letter-sound knowledge or some semantic information was available, and (3) visual memory, some letter-sound knowledge and some semantic information were all available. When only visual memory was available, orthographic learning (measured via an orthographic choice test) was meagre. Orthographic learning was significant when either semantic information or letter-sound knowledge supplemented visual memory, with letter-sound knowledge generating greater significance...
June 15, 2017: Journal of Psycholinguistic Research
https://www.readbyqxmd.com/read/28619016/clinical-application-of-a-novel-endoscopic-mask-a-randomized-controlled-multi-center-trial-in-patients-undergoing-awake-fiberoptic-bronchoscopic-intubation
#4
Tianxiao Zou, Zhenling Huang, Xiaoxue Hu, Guangyu Cai, Miao He, Shanjuan Wang, Ping Huang, Bin Yu
BACKGROUND: Awake fiberoptic bronchoscopic tracheal intubation is usually regarded as an effective method in the management of predicted difficult airway. Hypoxia during awake nasal fiberoptic bronchoscopic intubation leads to discontinuation of the procedure, prolonged manipulation time and increased risk of severe complications. The main aim of the study was to test whether the novel endoscopic mask is helpful for hypoxia during the intubation. METHODS: This was a randomized, controlled, multi-center study...
June 15, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28615157/designing-prototyping-and-evaluating-digital-mindfulness-applications-a-case-study-of-mindful-breathing-for-stress-reduction
#5
Bin Zhu, Anders Hedman, Shuo Feng, Haibo Li, Walter Osika
BACKGROUND: During the past decade, there has been a rapid increase of interactive apps designed for health and well-being. Yet, little research has been published on developing frameworks for design and evaluation of digital mindfulness facilitating technologies. Moreover, many existing digital mindfulness applications are purely software based. There is room for further exploration and assessment of designs that make more use of physical qualities of artifacts. OBJECTIVE: The study aimed to develop and test a new physical digital mindfulness prototype designed for stress reduction...
June 14, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28606006/a-beginner-s-guide-to-the-literature-search-in-medical-education
#6
S Martin, Z Hussain, J G Boyle
Conducting a literature search can be a daunting prospect if you have not done it before. This article aims to provide a beginner's guide to searching the medical education literature, by describing how to construct an effective search strategy, the resources that are available and the basics of how searching works.
January 1, 2017: Scottish Medical Journal
https://www.readbyqxmd.com/read/28604579/how-to-avoid-a-learning-curve-in-stapedotomy-a-standardized-surgical-technique
#7
Pingling Kwok, Otto Gleich, Katharina Dalles, Elisabeth Mayr, Peter Jacob, Jürgen Strutz
OBJECTIVE: To evaluate, whether a learning curve for beginners in stapedotomy can be avoided by using a prosthesis with thermal memory-shape attachment in combination with a standardized laser-assisted surgical technique. STUDY DESIGN: Retrospective case review. SETTING: Tertiary referral center. PATIENTS: Fifty-eight ears were operated by three experienced surgeons and compared with a group of 12 cases operated by a beginner in stapedotomy...
June 9, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28604375/retained-upper-third-molars-during-le-fort-i-osteotomy-with-downfracture
#8
Marco Friscia, Marzia Petrocelli, Carolina Sbordone, Raffaele Corvino, Fabio Maglitto, Francesco Maria Cassandro, Giorgio Iaconetta, Luigi Califano
AIM: The aim of our study is to demonstrate that the presence of upper wisdom teeth must be evaluated before and during Le Fort I osteotomy because attention must be focused to the disadvantages or facilitations of surgery depending on molar presence. MATERIALS OF STUDY: Our study has analyzed two groups, each one including 20 patients, 10 males and 10 females, with an age between 16-30 years. The first group was treated with le Fort I osteotomy leaving in situ the wisdom upper third molars...
2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28603585/international-scientific-communications-in-the-field-of-colorectal-tumour-markers
#9
Krasimir Ivanov, Ivan Donev
AIM: To analyze scientometrically the dynamic science internationalization on colorectal tumour markers as reflected in five information portals and to outline the significant journals, scientists and institutions. METHODS: A retrospective problem-oriented search was performed in Web of Science Core Collection (WoS), MEDLINE, BIOSIS Citation Index (BIOSIS) and Scopus for 1986-2015 as well as in Dervent Innovations Index (Derwent) for 1995-2015. Several specific scientometric parameters of the publication output and citation activity were comparatively analyzed...
May 27, 2017: World Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28594724/the-american-society-of-colon-and-rectal-surgeons-assessment-tool-for-performance-of-laparoscopic-colectomy
#10
Bradley J Champagne, Scott R Steele, Samantha K Hendren, Paul M Bakaki, Patricia L Roberts, Conor P Delaney, Justin T Brady, Helen M MacRae
BACKGROUND: The lack of consensus for performance assessment of laparoscopic colorectal resection is a major impediment to quality improvement. OBJECTIVE: The purpose of this study was to develop and assess the validity of an evaluation tool for laparoscopic colectomy that is feasible for wide implementation. DESIGN: During the pilot phase, a small group of experts modified previous assessment tools by watching videos for laparoscopic right colectomy with the following categories of experience: novice (less than 20 cases), intermediate (50-100 cases), and expert (more than 500 cases)...
July 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28578849/effectiveness-of-training-final-year-undergraduate-nutritionists-in-motivational-interviewing
#11
Trevor N Simper, Jeff D Breckon, Karen Kilner
OBJECTIVES: To assess the efficacy of a motivational interviewing (MI) training programme on trainee nutritionists. METHODS: A repeated measures design was applied to assess clinician behaviours in a 'helping' conversation. Participants were 32 nutrition students, assessed at baseline and one-month follow-up. RESULTS: The training significantly reduced the use of closed questions and MI non-adherent behaviours (MINA) (P for both=<0.001)...
May 13, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28578115/2d-hd-versus-3d-endoscopy-in-endonasal-skull-base-surgery-a-comparative-pre-clinical-study
#12
Vittorio Rampinelli, Francesco Doglietto, Davide Mattavelli, Jimmy Qiu, Elena Raffetti, Alberto Schreiber, Andrea Bolzoni Villaret, Walter Kucharczyk, Francesco Donato, Marco Maria Fontanella, Piero Nicolai
BACKGROUND: Three-dimensional (3D) endoscopy has been recently introduced in endonasal skull base surgery. Only a relatively limited number of studies have compared it to two-dimensional, high definition (2D-HD) technology. OBJECTIVE: To analyze, in a preclinical setting for endonasal endoscopic surgery, surgical maneuverability comparing 2D-HD and 3D endoscopy. METHODS: A group of 68 volunteers, both novice and experienced surgeons, were asked to perform two tasks, namely simulating grasping and dissection surgical maneuvers, in a model of the nasal cavities...
May 31, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28575143/seeing-the-wood-for-the-trees-a-forest-of-methods-for-optimization-and-omic-network-integration-in-metabolic-modelling
#13
Supreeta Vijayakumar, Max Conway, Pietro Lió, Claudio Angione
Metabolic modelling has entered a mature phase with dozens of methods and software implementations available to the practitioner and the theoretician. It is not easy for a modeller to be able to see the wood (or the forest) for the trees. Driven by this analogy, we here present a 'forest' of principal methods used for constraint-based modelling in systems biology. This provides a tree-based view of methods available to prospective modellers, also available in interactive version at http://modellingmetabolism...
May 30, 2017: Briefings in Bioinformatics
https://www.readbyqxmd.com/read/28573966/learning-navigation-learning-with-navigation-a-review
#14
Jean-Yves Jenny, Frederic Picard
The goal of this review paper is to retrieve from the existing literature relevant information (1) about the learning curve of the currently existing navigation systems and (2) about the use of navigation system for teaching orthopaedic procedures. All studies reporting on the learning curve of navigation systems support the hypothesis that computer-navigated total knee arthroplasty (TKA) involves only a short learning curve and that beginners can obtain good results from the beginning of their experience, as navigation provides continuous feedback during all phases of the knee replacement surgery and allows for correcting any bone cut errors...
2017: SICOT-J
https://www.readbyqxmd.com/read/28567413/healthebrain-an-innovative-smartphone-application-to-improve-cognitive-function-in-older-adults
#15
Erin M Shellington, Tina Felfeli, Ryosuke Shigematsu, Dawn P Gill, Robert J Petrella
BACKGROUND: Exercise-based interventions have shown promise in slowing cognitive decline, however there is limited evidence for scalability. Our previous research has linked a novel visuospatial memory exercise intervention, incorporating patterned walking or square-stepping exercise (SSE) with significant improvements in executive function and memory among older adults with normal cognition as well as those with subjective cognitive complaints (SCC) and mild cognitive impairment (MCI)...
2017: MHealth
https://www.readbyqxmd.com/read/28560125/learning-microvascular-anastomosis-in-low-socioeconomic-vascular-models-during-residency
#16
Karuna Tamrakar
Microvascular anastomosis procedure has become an essential practice for the management of most neurovascular diseases. Increasing use of neurosurgical techniques necessitates intensive laboratory training in microsurgery. Umbilical artery is used for quantifiable representation to set up microvascular anastomosis model for the beginners. These arteries are found to be between 4 and 5 mm in diameter. Chicken wings are set up as second anastomosis model. Five to six centimeter long brachial artery extracted from a chicken is measured approximately 1-2 mm in diameter...
April 27, 2017: Curēus
https://www.readbyqxmd.com/read/28558028/kidney-volume-measurement-methods-for-clinical-studies-on-autosomal-dominant-polycystic-kidney-disease
#17
Kanishka Sharma, Anna Caroli, Le Van Quach, Katja Petzold, Michela Bozzetto, Andreas L Serra, Giuseppe Remuzzi, Andrea Remuzzi
BACKGROUND: In autosomal dominant polycystic kidney disease (ADPKD), total kidney volume (TKV) is regarded as an important biomarker of disease progression and different methods are available to assess kidney volume. The purpose of this study was to identify the most efficient kidney volume computation method to be used in clinical studies evaluating the effectiveness of treatments on ADPKD progression. METHODS AND FINDINGS: We measured single kidney volume (SKV) on two series of MR and CT images from clinical studies on ADPKD (experimental dataset) by two independent operators (expert and beginner), twice, using all of the available methods: polyline manual tracing (reference method), free-hand manual tracing, semi-automatic tracing, Stereology, Mid-slice and Ellipsoid method...
2017: PloS One
https://www.readbyqxmd.com/read/28552698/a-novel-approach-for-percutaneous-vertebroplasty-based-on-preoperative-ct-based-3-dimensional-model-design-technical-note
#18
Jian Li, JiSheng Lin, JunChuan Xu, Hai Meng, Nan Su, ZiHan Fan, JinJun Li, Yong Yang, Dong Li, BingQiang Wang, Qi Fei
OBJECTIVE: To describe a new technique for the efficient use of preoperative planning based on preoperative CT-based 3-Dimensional model design for percutaneous vertebroplasty (PVP) in a patient with osteoporotic vertebral compression fracture (OVCF). METHODS: A 76-year-old woman with acute OVCF (L1 level) accepted a novel precise PVP. A 3D model of thoracolumbar vertebrae (T12-L2) based on preoperative CT scanning data and a simulative PVP (via bilateral transpedicular approach) were built in Materiaise's interactive medical image control system (MIMICS) software...
May 24, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28532508/is-it-possible-for-knowledge-based-planning-to-improve-intensity-modulated-radiation-therapy-plan-quality-for-planners-with-different-planning-experiences-in-left-sided-breast-cancer-patients
#19
Juanqi Wang, Weigang Hu, Zhaozhi Yang, Xiaohui Chen, Zhiqiang Wu, Xiaoli Yu, Xiaomao Guo, Saiquan Lu, Kaixuan Li, Gongyi Yu
BACKGROUND: Knowledge-based planning (KBP) is a promising technique that can improve plan quality and increase planning efficiency. However, no attempts have been made to extend the domain of KBP for planners with different planning experiences so far. The purpose of this study was to quantify the potential gains for planners with different planning experiences after implementing KBP in intensity modulated radiation therapy (IMRT) plans for left-sided breast cancer patients. METHODS: The model libraries were populated with 80 expert clinical plans from treated patients who previously received left-sided breast-conserving surgery and IMRT with simultaneously integrated boost...
May 22, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28531114/bodily-expression-support-for-creative-dance-education-by-grasping-type-musical-interface-with-embedded-motion-and-grasp-sensors
#20
Tomoyuki Yamaguchi, Hideki Kadone
Dance has been made mandatory as one of the physical education courses in Japan because it can cultivate capacities for expression and communication. Among several types of dance education, creative dance especially contributes to the cultivation of these capacities. However, creative dance requires some level of particular skills, as well as creativity, and it is difficult to presuppose these pre-requisites in beginner-level dancers without experience. We propose a novel supporting device for dance beginners to encourage creative dance performance by continuously generating musical sounds in real-time in accordance with their bodily movements...
May 20, 2017: Sensors
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