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https://www.readbyqxmd.com/read/28100981/isolated-left-subclavian-artery-complete-atrioventricular-block-and-tricuspid-atresia-in-a-neonate
#1
Kanupriya Chaturvedi, Deepa Prasad, Ravi Ashwath, James P Strainic, Christopher S Snyder
Isolated left subclavian artery is one of the rarer aortic arch anomalies. It has been associated with other congenital heart diseases, typically tetralogy of Fallot, double-outlet right ventricle, and atrial and ventricular septal defects. Its significant clinical implications include a left-to-right shunt from the vertebrobasilar system, which causes pulmonary overcirculation and subclavian steal. We present an unusual case of a premature infant who was diagnosed prenatally with congenital complete atrioventricular block and tricuspid atresia and was found to have an isolated left subclavian artery postnatally...
December 2016: Texas Heart Institute Journal
https://www.readbyqxmd.com/read/28097609/a-case-of-a-quadricuspid-aortic-valve-identified-preoperatively-using-transthoracic-echocardiography
#2
Takanori Kono, Takeshi Oda, Keiichi Akaiwa, Katsuhiko Nakamura, Hiroyuki Tanaka
Quadricuspid aortic valve is an extremely rare congenital heart anomaly that often causes valve incompetence, requiring surgical intervention. Care must be taken to avoid surgical complications in patients with quadricuspid aortic valve; thus, preoperative diagnosis is important. A 76-year-old man presented with exertional dyspnea due to aortic regurgitation. Transthoracic and transesophageal echocardiography revealed severe aortic regurgitation caused by quadricuspid aortic valve. To avoid interference with the cardiac conduction system, we performed aortic valve replacement using an ingenious technique, in which pledgeted sutures on the accessory leaflet were placed from outside the sinus of Valsalva to above the aortic annulus...
January 18, 2017: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/28086847/cardiac-sarcoidosis-resembling-panic-disorder-a-case-report
#3
Keita Tokumitsu, Jun Demachi, Yukichi Yamanoi, Shigeto Oyama, Junko Takeuchi, Koji Yachimori, Norio Yasui-Furukori
BACKGROUND: Sarcoidosis is a systemic disease of unknown etiology, in which granulomas develop in various organs, including the skin, lungs, eyes, or heart. It has been reported that patients with sarcoidosis are more likely to develop panic disorder than members of the general population. However, there are many unknown factors concerning the causal relationship between these conditions. CASE PRESENTATION: We present the case of a 57-year-old woman who appeared to have panic disorder, as she experienced repeated panic attacks induced by transient complete atrioventricular block, associated with cardiac sarcoidosis...
January 13, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28067707/dural-puncture-epidural-technique-improves-labor-analgesia-quality-with-fewer-side-effects-compared-with-epidural-and-combined-spinal-epidural-techniques-a-randomized-clinical-trial
#4
Anthony Chau, Carolina Bibbo, Chuan-Chin Huang, Kelly G Elterman, Eric C Cappiello, Julian N Robinson, Lawrence C Tsen
BACKGROUND: The dural puncture epidural (DPE) technique is a modification of the combined spinal epidural (CSE) technique, where a dural perforation is created from a spinal needle but intrathecal medication administration is withheld. The DPE technique has been shown to improve caudal spread of analgesia compared with epidural (EPL) technique without the side effects observed with the CSE technique. We hypothesized that the onset of labor analgesia would follow this order: CSE > DPE > EPL techniques...
February 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28051234/neonatal-lupus-erythematosus-with-congenital-heart-block-in-twins
#5
Lamia Gargouri, Faiza Safi, Bayen Maalej, Souad Mallek, Fatma Turki, Imen Majdoub, Malek Akrout, Dorra Abid, Samir Kamoun, Abdelmajid Mahfoudh
Background - Neonatal lupus erythematosus is an uncommon acquired autoimmune disease caused by transplacental passage of maternal antibodies SSA/Ro, SSB/La or U1 ribonucleoproteins. The most common clinical manifestations are skin rash, cardiac lesions, thrombocytopenia, anemia and hepatosplenomegaly. Complete congenital heart block is usually irreversible needing a pacemaker implantation in two-thirds of cases. Cases report - We report neonatal lupus erythematosus with complete congenital heart block in twins...
July 2016: La Tunisie Médicale
https://www.readbyqxmd.com/read/28042617/temporary-systemic-inhibition-of-the-wnt-%C3%AE-catenin-pathway-promotes-regenerative-cardiac-repair-following-myocardial-infarct
#6
Dikshya Bastakoty, Sarika Saraswati, Piyush Joshi, James Atkinson, Igor Feoktistov, Jun Liu, Jennifer L Harris, Pampee P Young
AIMS: The WNT/β-catenin pathway is temporarily activated in the heart following myocardial infarction (MI). Despite data from genetic models indicating both positive and negative roles for the WNT pathway depending on the model used, the effect of therapeutic inhibition of WNT pathway on post-injury outcome and the cellular mediators involved are not completely understood. Using a newly available, small molecule, GNF-6231, which averts WNT pathway activation by blocking secretion of all WNT ligands, we sought to investigate whether therapeutic inhibition of the WNT pathway temporarily after infarct can mitigate post injury cardiac dysfunction and fibrosis and the cellular mechanisms responsible for the effects...
November 2016: Cell Stem Cells Regen Med
https://www.readbyqxmd.com/read/28035645/reflex-arc-of-the-teeth-clenching-induced-pressor-response-in-rats
#7
Ichiro Shoji, Takehito Kemuriyama, Megumi Tandai-Hiruma, Satoshi Maruyama, Akimasa Tashiro, Hidetaka Yokoe, Yasuhiro Nishida
Although "teeth clenching" induces pressor response, the reflex tracts of the response are unknown. In this study, dantrolene administration inhibited teeth clenching generated by electrical stimulation of the masseter muscles and completely abolished the pressor response. In addition, trigeminal ganglion block or hexamethonium administration completely abolished the pressor response. Local anesthesia of molar regions significantly reduced the pressor response to 27 ± 10%. Gadolinium (mechanoreceptor blocker of group III muscle afferents) entrapment in masticatory muscles also significantly reduced the pressor response to 62 ± 7%...
December 29, 2016: Journal of Physiological Sciences: JPS
https://www.readbyqxmd.com/read/28034575/complete-right-bundle-branch-block-and-qrs-t-discordance-can-be-the-initial-clue-to-detect-s-icd-ineligibility
#8
Motomi Tachibana, Nobuhiro Nishii, Yoshimasa Morimoto, Satoshi Kawada, Akihito Miyoshi, Hiroyasu Sugiyama, Koji Nakagawa, Atsuyuki Watanabe, Kazufumi Nakamura, Hiroshi Morita, Hiroshi Ito
BACKGROUND: In order to minimize inappropriate shocks of subcutaneous implantable cardioverter-defibrillators (S-ICD), it is important to recognize who is suitable for S-ICD indication. This study aimed to clarify what types of cardiac disease are likely to fulfill the S-ICD screening criteria and ineligible factors for S-ICD in the standard 12-lead electrocardiogram (ECG). METHODS: A total of 348 patients with heart disease were enrolled. They were assessed by supine and standing ECG recording to simulate the 3 S-ICD sensing vectors and standard 12-lead ECG, simultaneously...
December 26, 2016: Journal of Cardiology
https://www.readbyqxmd.com/read/28034442/electrocardiographic-changes-induced-by-endurance-training-and-pubertal-development-in-male-children
#9
Flavio D'Ascenzi, Marco Solari, Francesca Anselmi, Francesca Valentini, Riccardo Barbati, Paola Palmitesta, Marta Focardi, Marco Bonifazi, Sergio Mondillo
Training-induced electrocardiographic changes are common in adult athletes. However, a few data are available on electrocardiogram (ECG) in preadolescent athletes and little is known about the potential changes induced by training on 12-lead electrocardiogram (ECG) at rest. Twelve-lead ECGs at rest and complete echocardiographic examinations were performed in 94 children (57 endurance athletes, 37 sedentary controls; mean age 10.8 ± 0.2 and 10.2 ± 0.2 years, respectively) at baseline and after 5 months of growth and training in athletes and of natural growth in controls...
December 3, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/28018021/exome-sequencing-identifies-compound-heterozygous-mutations-in-scn5a-associated-with-congenital-complete-heart-block-in-the-thai-population
#10
Chuphong Thongnak, Pornprot Limprasert, Duangkamol Tangviriyapaiboon, Suchaya Silvilairat, Apichaya Puangpetch, Ekawat Pasomsub, Chonlaphat Sukasem, Wasun Chantratita
Background. Congenital heart block is characterized by blockage of electrical impulses from the atrioventricular node (AV node) to the ventricles. This blockage can be caused by ion channel impairment that is the result of genetic variation. This study aimed to investigate the possible causative variants in a Thai family with complete heart block by using whole exome sequencing. Methods. Genomic DNA was collected from a family consisting of five family members in three generations in which one of three children in generation III had complete heart block...
2016: Disease Markers
https://www.readbyqxmd.com/read/28012774/-intermittent-left-bundle-branch-block-reversal-to-normal-conduction-during-general-anesthesia
#11
Ana Maria Oliveira Correia da Silva, Emília Alexandra Gaspar Lima da Silva
BACKGROUND AND OBJECTIVES: Transient changes in intraoperative cardiac conduction are uncommon. Rare cases of the development or remission of complete left bundle branch block under general and locoregional anesthesia associated with myocardial ischemia, hypertension, tachycardia, and drugs have been reported. Complete left bundle branch block is an important clinical manifestation in some chronic hypertensive patients, which may also be a sign of coronary artery disease, aortic valve disease, or underlying cardiomyopathy...
December 21, 2016: Revista Brasileira de Anestesiologia
https://www.readbyqxmd.com/read/28011836/new-insights-from-a-computational-model-on-the-relation-between-pacing-site-and-crt-response
#12
Marieke Pluijmert, Peter H M Bovendeerd, Joost Lumens, Kevin Vernooy, Frits W Prinzen, T Delhaas
AIMS: Cardiac resynchronization therapy (CRT) produces clinical benefits in chronic heart failure patients with left bundle-branch block (LBBB). The position of the pacing site on the left ventricle (LV) is considered an important determinant of CRT response, but the mechanism how the LV pacing site determines CRT response is not completely understood. The objective of this study is to investigate the relation between LV pacing site during biventricular (BiV) pacing and cardiac function...
December 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28000148/regadenoson-induced-complete-heart-block-and-asystole-a-real-possibility-nuclear-laboratories-should-be-aware-of
#13
Faraz Kureshi, Mouin S Abdallah, Timothy M Bateman
No abstract text is available yet for this article.
December 20, 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/27996100/complications-with-the-micra-tps-pacemaker-system-persistent-complete-heart-block-and-late-capture-failure
#14
Niels Holm, Andreas Müller, Rainer Zbinden
A Medtronic MICRA transcatheter pacing system (TPS) was implanted in an 86-year old patient with sick sinus syndrome and left bundle branch block after transfemoral aortic valve implantation. During implantation she developed a persistent complete heart block due to manipulation with the large bore delivery catheter. Two weeks later, acute pacemaker dysfunction occurred due to massive increase of pacing threshold and impedance without obvious pacemaker dislocation or myocardial perforation. Recurrent capture failure was seen with pacing output set at 5 V / 1...
December 20, 2016: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/27977016/heart-sounds-at-home-feasibility-of-an-ambulatory-fetal-heart-rhythm-surveillance-program-for-anti-ssa-positive-pregnancies
#15
B F Cuneo, A J Moon-Grady, S-E Sonesson, S Levasseur, L Hornberger, M T Donofrio, A Krishnan, A Szwast, L Howley, D W Benson, E Jaeggi
OBJECTIVE: Fetuses exposed to anti-SSA (Sjögren's) antibodies are at risk of developing irreversible complete atrioventricular block (CAVB), resulting in death or permanent cardiac pacing. Anti-inflammatory treatment during the transition period from normal heart rhythm (fetal heart rhythm (FHR)) to CAVB (emergent CAVB) can restore sinus rhythm, but detection of emergent CAVB is challenging, because it can develop in ⩽24 h. We tested the feasibility of a new technique that relies on home FHR monitoring by the mother, to surveil for emergent CAVB...
December 15, 2016: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/27965025/cardiovascular-outcomes-in-patients-with-intraventricular-conduction-blocks-sixteen-year-follow-up-in-a-statewide-database
#16
John S Pantazopoulos, Alice David, William J Kostis, Nora M Cosgrove, John B Kostis
BACKGROUND: To assess the adverse clinical effects of left anterior hemiblock alove or in combination with right bundle branch block and of complete left bundle branch block in comparison with isolated right bundle branch block, and relate these effects to altered mechanoelectric factors resulting in left ventricular dysfunction. METHODS: In a 16-year follow-up of a statewide database, we studied the occurrence of mortal and morbid cardiovascular (CV) events among patients without apparent ischemic heart disease who had left anterior hemiblock (LAHB, n=4273, right bundle branch block (RBBB) with LAHB (BFBB, n=1857) and left bundle branch block (LBBB, n=9484 as compared to isolated RBBB (n=25288)...
December 10, 2016: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/27943134/cooling-dynamics-a-new-predictor-of-long-term-efficacy-of-atrioventricular-nodal-reentrant-tachycardia-cryoablation
#17
Mario Matta, Matteo Anselmino, Marco Scaglione, Marco Vitolo, Federico Ferraris, Paolo Di Donna, Domenico Caponi, Davide Castagno, Fiorenzo Gaita
PURPOSE: Catheter ablation of the slow pathway is the most effective treatment for atrioventricular nodal reentrant tachycardia (AVNRT). Cryoenergy, compared to radiofrequency, relates to lower heart block risk but higher incidence of AVNRT recurrences. The aims of this study are to confirm the safety and efficacy of AVNRT cryoablation and to identify predictors of long-term recurrences. METHODS: Among 241 patients undergoing AVNRT cryoablation, 239 (99.2%) experienced acute effective cryoablation of the slow pathway, and no procedure-related complications were reported...
December 10, 2016: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/27941748/congenital-complete-heart-block-presenting-in-pregnancy-a-case-report
#18
S Rouf, A W Chowdhury
Congenital complete heart block presenting for the first time in pregnancy is a rare occurrence posing a therapeutic challenge. We present a case of unpaced preexisting congenital complete heart block in pregnancy diagnosed for the first time during routine prenatal care at her early weeks of gestation. Our patient was asymptomatic and haemodynamically stable and was managed conservatively with a multidisciplinary term approach. Intrauterine growth retardation (IUGR) was present and she was delivered by ceasarean section at term for foetal distress with IUGR...
October 2016: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/27924873/cardiac-specific-overexpression-of-mitochondrial-omi-htra2-induces-myocardial-apoptosis-and-cardiac-dysfunction
#19
Ke Wang, Yuexing Yuan, Xin Liu, Wayne Bond Lau, Lin Zuo, Xiaoliang Wang, Lu Ma, Kun Jiao, Jianyu Shang, Wen Wang, Xinliang Ma, Huirong Liu
Myocardial apoptosis is a significant problem underlying ischemic heart disease. We previously reported significantly elevated expression of cytoplasmic Omi/HtrA2, triggers cardiomyocytes apoptosis. However, whether increased Omi/HtrA2 within mitochondria itself influences myocardial survival in vivo is unknown. We aim to observe the effects of mitochondria-specific, not cytoplasmic, Omi/HtrA2 on myocardial apoptosis and cardiac function. Transgenic mice overexpressing cardiac-specific mitochondrial Omi/HtrA2 were generated and they had increased myocardial apoptosis, decreased systolic and diastolic function, and decreased left ventricular remodeling...
December 7, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27923584/role-of-18f-fluorodeoxyglucose-positron-emission-tomography-imaging-to-demonstrate-resolution-of-acute-myocarditis
#20
Natasha Aleksova, Daniel Juneau, Alexander Dick, Martin Green, David Birnie, Rob S Beanlands, Pablo B Nery
A young woman experienced complete heart block, leading to Torsades de pointes. Cardiac 18F-fluorodeoxyglucose/positron emission tomography was used to confirm the resolution of her acute myocarditis and was critical to the decision-making process that prevented unnecessary pacemaker insertion.
August 20, 2016: Canadian Journal of Cardiology
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