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https://www.readbyqxmd.com/read/29676256/-the-smile-a-challenge-in-the-treatment-of-class-iii
#1
Laure De Launay, Sarah Gebeile-Chauty
INTRODUCTION: The smile poses a challenge in the treatment of class III. Untreated, the class III patient presents excessive maxillary torque and a predominant display of the mandibular incisors, a sign that becomes more visible with age. Functional orthopedics restores the aesthetic appearance of the smile by maxillary protraction (sometimes temporarily because 20% of cases will still need surgery). Depending on the initial severity of the case (-4.5 mm AoBo would be the threshold value), the options are compensation or surgical correction...
March 2018: L' Orthodontie Française
https://www.readbyqxmd.com/read/29675673/systematic-review-of-the-complications-associated-with-magnetically-controlled-growing-rods-for-the-treatment-of-early-onset-scoliosis
#2
REVIEW
Chrishan Thakar, David Christopher Kieser, Mihai Mardare, Shahnawaz Haleem, Jeremy Fairbank, Colin Nnadi
PURPOSE: To analyse the complication profile of magnetically controlled growing rods (MCGRs) in early onset scoliosis (EOS). METHODS: This is a systematic review using PUBMED, Medline, Embase, Google Scholar and the Cochrane Library (keywords: MAGEC, Magnetically controlled growing rods and EOS) of all studies written in English with a minimum of five patients and a 1-year follow-up. We evaluated coronal correction, growth progression (T1-S1, T1-T12) and complications...
April 19, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29675508/are-trabecular-metal-cones-a-valid-option-to-treat-metaphyseal-bone-defects-in-complex-primary-and-revision-knee-arthroplasty
#3
REVIEW
Tommaso Bonanzinga, Thorsten Gehrke, Akos Zahar, Stefano Zaffagnini, Maurilio Marcacci, Carl Haasper
Purpose  Metaphyseal bone defects are a challenge in complex primary and revision total knee arthroplasty (TKA). Recently, several studies have been published with promising results about the use of Trabecular Metal (TM) cones to address bone defects. The aim of this study is to review the literature to assess the efficacy of TM cones to address metaphyseal bone loss. Methods  A comprehensive search was performed on PubMed, Medline, CINAHL, Cochrane, Embase, and Google Scholar databases using various combinations of the following keywords: "metaphyseal," "cones," "tantalum," "knee," and "revision...
March 2018: Joints
https://www.readbyqxmd.com/read/29675045/paediatric-autoimmune-neuropsychiatric-disorder-associated-with-group-a-beta-haemolytic-streptococcal-infection-an-indication-for-tonsillectomy-a-review-of-the-literature
#4
REVIEW
Amarkumar Dhirajlal Rajgor, Navid Akhtar Hakim, Sanah Ali, Adnan Darr
Background. Paediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infection (PANDAS) is the acute onset of neuropsychiatric symptoms following group A beta-haemolytic streptococcal infection. The aetiology remains elusive. However, with group A streptococcus being the most common bacterial cause of tonsillitis, surgical intervention in the form of tonsillectomy has often been considered as a potential therapy. Methods. A MEDLINE® search was undertaken using keywords "PANDAS" or "paediatric autoimmune neuropsychiatric disorders associated with streptococcus" combined with "tonsillectomy"...
2018: International Journal of Otolaryngology
https://www.readbyqxmd.com/read/29673035/climate-change-and-the-health-of-older-people-in-australia-a-scoping-review-on-the-role-of-mobile-applications-apps-in-ameliorating-impact
#5
REVIEW
Deborah A Black, Kate O'Loughlin, Leigh A Wilson
OBJECTIVES: Due to the impact of climate change, mobile applications (apps) providing information about the external environment have the potential to improve the health of older people. The purpose of this research was to undertake a scoping review of the evidence on the usability, feasibility and effectiveness of mobile apps to encourage access to activities outside the home in older people. METHODS: A search of databases was undertaken with relevant keywords...
April 19, 2018: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/29672874/review-article-novel-oral-targeted-therapies-in-inflammatory-bowel-disease
#6
REVIEW
J R White, F Phillips, T Monaghan, W Fateen, S Samuel, S Ghosh, G W Moran
BACKGROUND: There is a great unmet clinical need for efficacious, tolerable, economical and orally administrated drugs for the treatment of inflammatory bowel disease (IBD). New therapeutic avenues have become possible including the development of medications that target specific genetic pathways found to be relevant in other immune mediated diseases. AIMS: To provide an overview of recent clinical trials for new generation oral targeted medications that may have a future role in IBD management...
April 19, 2018: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29672851/human-hepatocellular-carcinoma-protection-by-melatonin
#7
REVIEW
Keywan Mortezaee
Despite great scientific breakthroughs toward understanding the identity of human hepatocellular carcinoma (HCC) mechanistically, there are still no clinically efficient therapeutic methods for this cancer. Melatonin (N-acetyl-5-methoxytryptamine) is a multi-tasking hormone that has long been known for its anti-cancer activity against various human cancers including HCC, which is a focus of this review. PubMed database was searched for relevant articles with the keywords: hepatocellular carcinoma (HCC), melatonin, apoptosis, proliferation, invasion, angiogenesis, autophagy, oxidative stress, tumor immunity, and mitogen-activated protein kinase (MAPK) focusing on just human cell lines and English language articles...
April 19, 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29672647/mapping-the-knowledge-structure-of-frailty-in-journal-articles-by-text-network-analysis
#8
Youngji Kim, Soong-Nang Jang
BACKGROUNDS: This study was to understand the trends of frailty research and networking features of keywords from the academic articles focusing on frailty in the last four decades. METHOD: Keywords were extracted from articles (n = 6,424) retrieved from Web of Science, from 1981 to April 2016, using Bibexcel, and a social network analysis was conducted using Net Miner. RESULTS: The core-keywords of research on frailty are constantly changing over the last 40 years...
2018: PloS One
https://www.readbyqxmd.com/read/29671803/physical-activity-and-cognitive-functioning-of-children-a-systematic-review
#9
REVIEW
Ilona Bidzan-Bluma, Małgorzata Lipowska
Childhood is an important and sensitive period for cognitive development. There is limited published research regarding the relationship between sports and cognitive functions in children. We present studies that demonstrate the influence of physical activity on health, especially a positive correlation between sports and cognitive functions. The keywords “children, cognition, cognitive function, physical activity, and brain” were searched for using PsycInfo, Medline, and Google Scholar, with publication dates ranging from January 2000 to November 2017...
April 19, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29671089/porous-metal-cones-gold-standard-for-massive-bone-loss-in-complex-revision-knee-arthroplasty-a-systematic-review-of-current-literature
#10
Stefano Divano, Luca Cavagnaro, Andrea Zanirato, Marco Basso, Lamberto Felli, Matteo Formica
INTRODUCTION: Revision knee arthroplasty is increasing, and in that case, bone loss management is still a challenging problem. In the last years, the body of literature and interest surrounding porous metal cones has grown, but few systematic evaluations of the existing evidence have been performed. The aim of our systematic review is to collect and critically analyze the available evidence about metal cones in revision knee arthroplasty especially focusing our attention on indications, results, complications, and infection rate of these promising orthopaedic devices...
April 18, 2018: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29670648/stimulating-the-healthy-brain-to-investigate-neural-correlates-of-motor-preparation-a-systematic-review
#11
REVIEW
Cécilia Neige, Hugo Massé-Alarie, Catherine Mercier
Objective: Noninvasive brain stimulation techniques can be used to selectively increase or decrease the excitability of a cortical region, providing a unique opportunity to assess the causal contribution of that region to the process being assessed. The objective of this paper is to systematically examine studies investigating changes in reaction time induced by noninvasive brain stimulation in healthy participants during movement preparation. Methods: A systematic review of the literature was performed in the PubMed, MEDLINE, EMBASE, PsycINFO, and Web of science databases...
2018: Neural Plasticity
https://www.readbyqxmd.com/read/29669703/physical-activity-sedentary-behavior-and-diet-related-ehealth-and-mhealth-research-bibliometric-analysis
#12
REVIEW
Andre Matthias Müller, Carol A Maher, Corneel Vandelanotte, Melanie Hingle, Anouk Middelweerd, Michael L Lopez, Ann DeSmet, Camille E Short, Nicole Nathan, Melinda J Hutchesson, Louise Poppe, Catherine B Woods, Susan L Williams, Petra A Wark
BACKGROUND: Electronic health (eHealth) and mobile health (mHealth) approaches to address low physical activity levels, sedentary behavior, and unhealthy diets have received significant research attention. However, attempts to systematically map the entirety of the research field are lacking. This gap can be filled with a bibliometric study, where publication-specific data such as citations, journals, authors, and keywords are used to provide a systematic overview of a specific field...
April 18, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29669592/ggdonto-ontology-as-a-knowledge-base-for-genetic-diseases-and-disorders-of-glycan-metabolism-and-their-causative-genes
#13
Elena Solovieva, Toshihide Shikanai, Noriaki Fujita, Hisashi Narimatsu
BACKGROUND: Inherited mutations in glyco-related genes can affect the biosynthesis and degradation of glycans and result in severe genetic diseases and disorders. The Glyco-Disease Genes Database (GDGDB), which provides information about these diseases and disorders as well as their causative genes, has been developed by the Research Center for Medical Glycoscience (RCMG) and released in April 2010. GDGDB currently provides information on about 80 genetic diseases and disorders caused by single-gene mutations in glyco-related genes...
April 18, 2018: Journal of Biomedical Semantics
https://www.readbyqxmd.com/read/29669512/a-systematic-review-of-transmission-dynamic-studies-of-methicillin-resistant-staphylococcus-aureus-in-non-hospital-residential-facilities
#14
Kin On Kwok, Jonathan M Read, Arthur Tang, Hong Chen, Steven Riley, Kai Man Kam
BACKGROUND: Non-hospital residential facilities are important reservoirs for MRSA transmission. However, conclusions and public health implications drawn from the many mathematical models depicting nosocomial MRSA transmission may not be applicable to these settings. Therefore, we reviewed the MRSA transmission dynamics studies in defined non-hospital residential facilities to: (1) provide an overview of basic epidemiology which has been addressed; (2) identify future research direction; and (3) improve future model implementation...
April 18, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29669506/mutations-and-common-polymorphisms-in-adamts13-and-vwf-genes-responsible-for-increasing-risk-of-thrombosis
#15
Habib Haybar, Elahe Khodadi, Maria Kavianpour, Najmaldin Saki
BACKGROUND AND OBJECTIVE: ADAMTS13 (A Disintegrin-like and Metalloproteases with Thrombospondin type-1 repeats, member-13) plays an important role in vascular hemostasis by cleaving the von Willebrand Factor (vWF). ADAMTS13 and vWF are involved in the development of ischemic heart disease. In this review paper, we examine the effects of single nucleotide polymorphisms (SNPs) and mutations in the vWF and ADAMTS13 genes and their contribution to the development of thrombosis. METHODS: Relevant English-language literature were searched and retrieved from PubMed search engine (2001-2017)...
April 18, 2018: Cardiovascular & Hematological Disorders Drug Targets
https://www.readbyqxmd.com/read/29668935/systematic-review-of-diagnostic-pathways-for-patients-presenting-with-acute-abdominal-pain
#16
Kirsten J de Burlet, Andrew J Ing, Peter D Larsen, Elizabeth R Dennett
Purpose: Abdominal pain is the most common reason for surgical referral. Imaging, aids early diagnosis and treatment. However unnecessary requests are associated with increased costs, radiation exposure and increased length of stay. Pathways can improve the quality of the diagnostic process. The aim of this systematic review was to identify the current evidence for diagnostic pathways and their use of imaging and effect on final outcomes. Data sources: A systematic search of Embase, Medline and Cochrane databases was performed using keywords and MeSH terms for abdominal pain...
April 13, 2018: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29668583/a-prisma-systematic-review-and-meta-analysis-on-chlamydia-trachomatis-infections-in-iranian-women-1986-2015
#17
Daem Roshani, Rashid Ramazanzadeh, Fariba Farhadifar, Amjad Ahmadi, Safoura Derakhshan, Samaneh Rouhi, Shamsi Zarea, Farnaz Zandvakili
BACKGROUND: Chlamydia trachomatis (CT) is the cause of genital tract infections in women. Some evidence has shown the role of this infection with CT in spontaneous abortions. The purpose of this study is to study the frequency of CT infection in Iranian women. METHODS: This study was performed based on PRISMA guidelines. A total of 75 articles published in Google Scholar, PubMed, ISI Web of Science, Biological abs, Iranmedex, SID, and Scopus databases were found (1986-2015) using the following keywords: CT in women, CT and Iranian women, CT and infection in Iran, CT and pregnancy in Iran, CT and preterm delivery in Iran, CT and preterm labor in Iran, CT and fertility in Iran, CT and infertility in Iran, and CT and abortion in Iran...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29668484/flexible-gas-sensor-based-on-graphene-ethyl-cellulose-nanocomposite-with-ultra-low-strain-response-for-volatile-organic-compounds-rapid-detection
#18
Qiankun Zhang, Chunhua An, Shuangqing Fan, Sigang Shi, Rongjie Zhang, Jing Zhang, Quanning Li, Daihua Zhang, Xiaodong Hu, Jing Liu
Minimizing the strain induced undesirable effects is one of the major efforts to be made for flexible electronics. This work reports a highly sensitive flexible gas sensor with ultra-low strain response, which is potentially suitable for wearable electronics applications. The gas sensing material is a free-standing and flexible thin film made of graphene/ethyl cellulose (EC) nanocomposite, which is then integrated with flexible substrate of polyethylene terephthalate. The sensor exhibits relative resistance change within 0...
April 18, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29667796/isotretinoin-the-ups-are-just-as-troubling-as-the-downs
#19
Jay M Truitt, Jason S Reichenberg, Kevin G Sharghi, Shirlene M Sampson, Randall K Roenigk, Michelle Magid
INTRODUCTION: Isotretinoin, previously marketed as Accutane®, is an oral retinoid medication that is used to treat acne and other cutaneous disorders. Although the data is conflicting, previous reports suggest a causal relationship between isotretinoin and depression. When reviewing these previous reports, many patients who were diagnosed as 'depressed' did not undergo a thorough psychiatric evaluation and/or were not diagnosed according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders (DSM)...
April 18, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29667145/ethical-challenges-faced-by-healthcare-professionals-who-care-for-suicidal-patients-a-scoping-review
#20
Victoria Saigle, Eric Racine
For each one of the approximately 800,000 people who die from suicide every year, an additional twenty people attempt suicide. Many of these attempts result in hospitalization or in contact with other healthcare services. However, many personal, educational, and institutional barriers make it difficult for healthcare professionals to care for suicidal individuals. We reviewed literature that discusses suicidal patients in healthcare settings in order to highlight common ethical issues and to identify knowledge gaps...
April 17, 2018: Monash Bioethics Review
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