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https://www.readbyqxmd.com/read/28822042/implementation-of-a-big-data-accessing-and-processing-platform-for-medical-records-in-cloud
#1
Chao-Tung Yang, Jung-Chun Liu, Shuo-Tsung Chen, Hsin-Wen Lu
Big Data analysis has become a key factor of being innovative and competitive. Along with population growth worldwide and the trend aging of population in developed countries, the rate of the national medical care usage has been increasing. Due to the fact that individual medical data are usually scattered in different institutions and their data formats are varied, to integrate those data that continue increasing is challenging. In order to have scalable load capacity for these data platforms, we must build them in good platform architecture...
August 18, 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28821817/high-mrna-expression-level-of-il-6r-was-associated-with-better-prognosis-for-patients-with-ovarian-cancer-a-pooled-meta-analysis
#2
Qu Chen, Bin Xu, Lei Lan, Da Yang, Min Yang, Jingting Jiang, Binfeng Lu, Yueping Shen
Interleukin-6 acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. IL-6/IL-6R signaling pathway, in particular, has been proposed to be a pivotal cytokine promoting ovarian cancer progression. This study aimed to elucidate potential clinical and biological function of IL-6R mRNA expression in ovarian cancer. We used the keywords "ovarian cancer" and searched through GEO database and finally a total of 7 studies together with TCGA database were incorporated in this analysis. We used Cutoff Finder to determine a cutoff point and stratified patients into two groups and found that high-expression of IL-6R mRNA in tumor tissues was a positive prognostic factor for overall survival...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821194/primary-benign-and-malignant-thyroid-neoplasms-with-signet-ring-cells-cytologic-histologic-and-molecular-features
#3
Nada A Farhat, Ayse M Onenerk, Jeffrey F Krane, Dora Dias-Santagata, Peter M Sadow, William C Faquin
Objectives: Signet ring cells (SRCs) can be seen in a variety of thyroid tumors and can pose a diagnostic pitfall on cytology. This study describes the cytologic, histomorphologic, and molecular aspects of a cohort of primary thyroid tumors with SRCs. Methods: A search was performed of the Massachusetts General Hospital and Brigham and Women's Hospital (Boston, MA) pathology archives for the keywords thyroid, signet, and signet ring features between 2000 and 2014...
September 1, 2017: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28819339/depression-after-stroke-in-sub-saharan-africa-a-systematic-review-and-meta-analysis
#4
REVIEW
Akin Ojagbemi, Onoja Akpa, Fisayo Elugbadebo, Mayowa Owolabi, Bruce Ovbiagele
OBJECTIVE: We aimed to conduct a systematic review and meta-analysis of prevalence and characteristics of poststroke depression (PSD) in sub-Saharan Africa (SSA). METHODS: We searched Medline, PsycINFO, and African Journals OnLine using keywords for stroke and depression and the .mp. operator for all 54 SSA countries/regions. Further information was retrieved through a manual search of references from relevant published and unpublished articles. We included only peer-reviewed original studies with epidemiological or experimental designs, conducted random-effect meta-analysis, and identified the most commonly associated factors by weight (inverse of variance method)...
2017: Behavioural Neurology
https://www.readbyqxmd.com/read/28817378/health-policy-making-for-street-children-challenges-and-strategies
#5
Fatemeh Abdi, Sara Esmaelzadeh Saeieh, Nasibeh Roozbeh, Mansoureh Yazdkhasti
Background The phenomenon of street children is a bio-psychological and social issue that not only harms children, but also endangers the health of a society. In line with the national programs for the development and promotion of street children's health in Iran, health policy making and essential strategies for this group of children will be presented in this paper. This paper will discuss the main issues and challenges of street children's health and, also, health policy and guidelines for this population...
August 17, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28815224/a-picture-is-worth-a-thousand-words-electronic-cigarette-content-on-instagram-and-pinterest
#6
Alexander S Lee, Joy L Hart, Clara G Sears, Kandi L Walker, Allison Siu, Courteney Smith
INTRODUCTION: This study examined electronic cigarette (e-cig) content in visual materials posted on the social-media platforms Instagram and Pinterest. Both platforms allow users to upload pictures to the internet and share them globally. Users can search for pictures tagged with specific keywords and phrases. METHODS: Using content analysis, this study identified themes in image postings of e-cigs on social media. During five weeks of data collection, keywords were used to identify pictures related to e-cigs...
July 2017: Tobacco Prevention & Cessation
https://www.readbyqxmd.com/read/28815020/advances-on-minimally-invasive-approach-for-benign-total-hysterectomy-a-systematic-review
#7
REVIEW
Marina de Paula Andres, Giuliano Moysés Borrelli, Mauricio Simões Abrão
Hysterectomy is one of the most commonly performed gynecologic surgeries, mainly for uterine myomas, abnormal uterine bleeding, and prolapses. It can be performed through several routes, each of which has its advantages and disadvantages. We conducted this systematic review to evaluate recent advances in surgical outcomes of benign total hysterectomies by any route: vaginal (VH), laparoscopic (LH), laparoscopically assisted vaginal (LAVH), single-port (SP), and robotic-assisted laparoscopy (RH). The search was applied to the PubMed electronic database by using keywords "hysterectomy" and "uterine benign disease", "adenomyosis", and "myoma"...
2017: F1000Research
https://www.readbyqxmd.com/read/28814548/chorioamnionitis-in-the-development-of-cerebral-palsy-a-meta-analysis-and-systematic-review
#8
REVIEW
Zhongjie Shi, Lin Ma, Kehuan Luo, Monika Bajaj, Sanjay Chawla, Girija Natarajan, Henrik Hagberg, Sidhartha Tan
CONTEXT: Chorioamnionitis (CA) has often been linked etiologically to cerebral palsy (CP). OBJECTIVES: To differentiate association from risk of CA in the development of CP. DATA SOURCES: PubMed, Cochrane Library, Embase, and bibliographies of original studies were searched by using the keywords (chorioamnionitis) AND ((cerebral palsy) OR brain). STUDY SELECTION: Included studies had to have: (1) controls, (2) criteria for diagnoses, and (3) neurologic follow-up...
June 2017: Pediatrics
https://www.readbyqxmd.com/read/28814245/benefits-of-sglt2-inhibitors-beyond-glycemic-control-a-focus-on-metabolic-cardiovascular-and-renal-outcomes
#9
Molly G Minze, Kayley Will, Brian T Terrell, Robin L Black, Brian K Irons
BACKGROUND: Sodium-glucose co-transporter 2 (SGLT2) inhibitors are a new pharmacotherapeutic class for the treatment of type 2 diabetes mellitus (T2DM). OBJECTIVE: To evaluate beneficial effects of the SGLT2 inhibitors on metabolic, cardiovascular, and renal outcomes. METHODS: A Pub-Med search (1966 to July 2017) was performed of published English articles using keywords sodium-glucose co-transporter 2 inhibitors, canagliflozin, dapagliflozin, and empagliflozin...
August 16, 2017: Current Diabetes Reviews
https://www.readbyqxmd.com/read/28811831/potent-phosphodiesterase-inhibition-and-nitric-oxide-release-stimulation-of-anti-impotence-thai-medicinal-plants-from-manosroi-iii-database
#10
Aranya Manosroi, Theeraphong Tangjai, Charinya Chankhampan, Worapaka Manosroi, Yaravee Najarut, Worapong Kitdamrongtham, Jiradej Manosroi
Seven plants in the top rank were selected from the "MANOSROI III" database using the two Thai keywords which meant impotence and sexual tonic. Boesenbergia rotunda (L.) Mansf. extract [EDP1-001(1)] gave the highest PDE inhibition activity of 4.36-fold sildenafil, a standard anti-impotence drug. Plumbago indica Linn. extract [EDP2-001(1)] exhibited the highest NO release stimulation activity of 666.85% which was 1.50-fold acetylcholine, a standard drug. Most selected plant extracts were nontoxic to EA.hy926 cells at 1...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28810937/tweets-gangs-and-guns-a-snapshot-of-gang-communications-in-detroit
#11
Desmond Patton, Sadiq Patel, Jun Sung Hong, Megan Ranney, Marie Crandall, Lyle Dungy
The aim of this study is to determine the frequency of violent and criminal Twitter communications among gang-affiliated individuals in Detroit, Michigan. We analyzed 8.5 million Detroit gang members' tweets from January 2013 to March 2014 to assess whether they contained Internet banging-related keywords. We found that 4.7% of gangaffiliated user tweets consisted of terms related to violence and crime. Violence and crime-related communications fell into 4 main categories: (a) beefing (267,221 tweets), (b) grief (79,971 tweets), (c) guns (3,551 tweets), and (d) substance use and distribution (47,638 tweets)...
August 15, 2017: Violence and Victims
https://www.readbyqxmd.com/read/28809453/a-meta-analysis-micrornas-prognostic-function-in-patients-with-nonsmall-cell-lung-cancer
#12
REVIEW
Na Yu, Qingjun Zhang, Qing Liu, Jiayu Yang, Sheng Zhang
Accumulating papers have demonstrated that microRNAs play an important role in the progression of lung cancer, mainly as oncogenic and tumor suppressive. Therefore, microRNAs may influence the survival of lung cancer patients. In this meta-analysis, we evaluated the role of microRNAs in affecting the overall survival in nonsmall cell lung cancer (NSCLC) patients, which may provide valuable information for the treatment of nonsmall cell lung cancer. We used keywords to retrieve literatures from online databases PUBMED, EMBASE and Web of Science and included 12 studies into our investigation according to pre-set criteria...
August 15, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/28809371/the-role-of-micrornas-in-oral-lichenoid-disorders-systematic-review
#13
A Setién-Olarra, M-L Gainza-Cirauqui, J-M Aguirre-Urizar, X Marichalar-Mendia
BACKGROUND: Certain changes in the microRNA expression are considered to be associated with chronic inflammatory processes and with the malignant transformation of oral potentially malignant disorders. The purpose of this systematic review is to update the existing data on the aberrant microRNA expression profiles identified in oral lichenoid disease (OLD). MATERIAL AND METHODS: A search in PubMed-Medline and Scopus was performed on the English literature published between 2010 and August 2016 using the following keywords: oral lichenoid disease, oral lichen planus and microRNA...
August 15, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/28808876/changes-of-cerebrospinal-fluid-a%C3%AE-42-t-tau-and-p-tau-in-parkinson-s-disease-patients-with-cognitive-impairment-relative-to-those-with-normal-cognition-a-meta-analysis
#14
Xiaohui Hu, Yan Yang, Daokai Gong
The cerebrospinal fluid (CSF) signature of reduced amyloid beta 1-42 (Aβ42), elevated total tau (t-tau), and phosphorylated tau181 (p-tau) is important for the early diagnosis of Alzheimer's disease (AD). Aβ42, t-tau, and p-tau have been reported in numerous studies to contribute to predicting cognitive impairment in Parkinson's disease (PDCI). However, no consistent conclusion can be drawn so far. Literatures regarding Aβ42, t-tau, and p-tau in CSF were systematically reviewed, and a meta-analysis was thus performed to evaluate the changes of these biomarkers in PDCI patients, including PD with mild cognitive impairment (PDMCI) and PD dementia (PDD) patients, relative to PD with normal cognition (PDNC) patients...
August 14, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28808792/using-natural-language-processing-of-free-text-radiology-reports-to-identify-type-1-modic-endplate-changes
#15
Hannu T Huhdanpaa, W Katherine Tan, Sean D Rundell, Pradeep Suri, Falgun H Chokshi, Bryan A Comstock, Patrick J Heagerty, Kathryn T James, Andrew L Avins, Srdjan S Nedeljkovic, David R Nerenz, David F Kallmes, Patrick H Luetmer, Karen J Sherman, Nancy L Organ, Brent Griffith, Curtis P Langlotz, David Carrell, Saeed Hassanpour, Jeffrey G Jarvik
Electronic medical record (EMR) systems provide easy access to radiology reports and offer great potential to support quality improvement efforts and clinical research. Harnessing the full potential of the EMR requires scalable approaches such as natural language processing (NLP) to convert text into variables used for evaluation or analysis. Our goal was to determine the feasibility of using NLP to identify patients with Type 1 Modic endplate changes using clinical reports of magnetic resonance (MR) imaging examinations of the spine...
August 14, 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/28808632/survival-rates-against-fracture-of-endodontically-treated-posterior-teeth-restored-with-full-coverage-crowns-or-resin-composite-restorations-a-systematic-review
#16
REVIEW
Warattama Suksaphar, Danuchit Banomyong, Titalee Jirathanyanatt, Yaowaluk Ngoenwiwatkul
This systematic review aims to summarize the current clinical studies that investigated survival rates against fracture of endodontically treated posterior teeth restored with crowns or resin composite restorations. Literature search were performed using keywords. Publications from 1980 to 2016 were searched in PubMed, ScienceDirect, Web of Science, MEDLINE, and SCOPUS. Included studies were selected based on inclusion and exclusion criteria. Three clinical studies were included: 1 randomized controlled trial and 1 prospective and 1 retrospective cohort studies...
August 2017: Restorative Dentistry & Endodontics
https://www.readbyqxmd.com/read/28808629/return-to-sport-following-tibial-plateau-fractures-a-systematic-review
#17
Greg A J Robertson, Seng J Wong, Alexander M Wood
AIM: To systemically review all studies reporting return to sport following tibial plateau fracture, in order to provide information on return rates and times to sport, and to assess variations in sporting outcome for different treatment methods. METHODS: A systematic search of CINAHAL, Cochrane, EMBASE, Google Scholar, MEDLINE, PEDro, Scopus, SPORTDiscus and Web of Science was performed in January 2017 using the keywords "tibial", "plateau", "fractures", "knee", "athletes", "sports", "non-operative", "conservative", "operative", "return to sport"...
July 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/28808609/optimizing-peripheral-blood-stem-cells-transplantation-outcome-through-amend-relapse-and-graft-failure-a-review-of-current-literature
#18
REVIEW
Saeed Mohammadi, Amir Hossein Norooznezhad, Ashraf Malek Mohammadi, Hajar Nasiri, Mohsen Nikbakht, Najmaldin Saki, Mohammad Vaezi, Kamran Alimoghaddam, Ardeshir Ghavamzadeh
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) has been considered as a valuable approach in treatment of numerous malignant and none malignant hematologic disorders. However, relapse and poor graft function (PGF) after allo-SCT remain to be controversial issues which may affect the transplantation outcome. Relevant articles were searched in MEDLINE database (2000-2016) using keywords and phrases: donor lymphocyte infusions, allogeneic stem cells transplantation, relapsed hematologic malignancies, booster schedules, cell dose, laboratory monitoring protocols and technical aspects of apheresis...
2017: Experimental Hematology & Oncology
https://www.readbyqxmd.com/read/28808449/efficacy-of-enamel-matrix-derivative-in-vital-pulp-therapy-a-review-of-literature
#19
REVIEW
Shariq Najeeb, Zohaib Khurshid, Muhammad Sohail Zafar, Sana Zohaib, Fahad Siddiqui
INTRODUCTION: Vital pulp therapy (VPT) aims to preserve the health and maintain life of the tooth pulp which has been compromised by caries, trauma or restorative procedures. Recently, enamel matrix derivative (EMD) has been introduced as a material for vital pulp therapy. The aim of this review is to critically analyze and summarize the available literature on EMD for VPT. METHODS AND MATERIALS: Online databases (PubMED/MEDLINE, Google Scholar, ISI Web of Science, and Wiley-Online) were searched by using the following keywords in various combinations: Enamel Matrix Derivative, Emdogain, 'Vital Pulp Therapy, 'Apexogenisis', Apexification, Pulp Capping, Endodontics, Dentine and Pulpotomy for studies indexed from January 1949 to April 2016...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28806822/-multiple-myeloma-current-status-in-diagnostic-testing-and-therapy
#20
Michael Kehrer, Sebastian Koob, Andreas Strauss, Dieter Christian Wirtz, Jan Schmolders
Background Multiple myeloma is a haematological blood cancer of the bone marrow and is classified by the World Health Organisation (WHO) as a plasma cell neoplasm. In multiple myeloma, normal plasma cells transform into malignant myeloma cells and produce large quantities of an abnormal immunoglobulin called monoclonal protein or M protein. This ultimately causes multiple myeloma symptoms such as bone damage or kidney problems. The annual worldwide incidence of multiple myeloma is estimated to be 6 - 7/100,000 and accounts for 1% of all cancer...
August 14, 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
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