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magnesium citrate

Alejandro Gabriel G Gonzalez Garay, Daniel Molano Franco, Víctor H Nieto Estrada, Arturo J Martí-Carvajal, Ingrid Arevalo-Rodriguez
BACKGROUND: High altitude illness (HAI) is a term used to describe a group of mainly cerebral and pulmonary syndromes that can occur during travel to elevations above 2500 metres (˜ 8200 feet). Acute mountain sickness (AMS), high altitude cerebral oedema (HACE) and high altitude pulmonary oedema (HAPE) are reported as potential medical problems associated with high altitude ascent. In this second review, in a series of three about preventive strategies for HAI, we assessed the effectiveness of five of the less commonly used classes of pharmacological interventions...
March 12, 2018: Cochrane Database of Systematic Reviews
Mohammad A Shafiee, Mehdi Aarabi, Pouyan Shaker, Amir M Ghafarian, Pouyan Chamanian, Mitchell L Halperin
PURPOSE: Intermittent fasting and curtailing water intake for extended periods of time was likely to be common in Paleolithic times. Nowadays, it occurs for religious and dietary reasons. This restriction in intake should cause a decrease in urine flow rate (UFR), while raising the concentrations of certain substances in the urine to the point of precipitation. In this study, we measured the risk of calcium phosphate (CaHPO4) precipitation following 18 hours of food and water deprivation...
March 1, 2018: Journal of Urology
Seung In Seo, Jin Gu Kang, Hyoung Su Kim, Myoung Kuk Jang, Hak Yang Kim, Woon Geon Shin
BACKGROUND/AIM: Previous studies comparing 2-L polyethylene glycol (PEG)-based solution with ascorbic acid (PEG/Asc) with sodium picosulfate/magnesium citrate (SP/MC) drew inconclusive results. This study aimed to compare a 2-L-PEG/Asc with SP/MC by split method in bowel cleansing efficacy, tolerability, and safety and to identify factors influencing inadequate bowel preparation. METHOD: We performed a prospective randomized, endoscopist-blinded, single-center, controlled trial...
March 1, 2018: International Journal of Colorectal Disease
Qing Wang, Weijie Hu, Yuchao Lu, Henglong Hu, Jiaqiao Zhang, Shaogang Wang
To study the impact of body mass index (BMI) on quantitative 24-h urine chemistries in stone forming patients and to explore how overweight and obesity contribute to urolithiasis. A systematic search of PubMed, EMBASE, Cochrane Library, and Web of Science was performed in July 2017 and updated in October 2017 to detect relevant studies. After that, we screened all the relevant articles in accordance with the predetermined inclusion and exclusion criteria. Data of eligible studies were extracted, and then, a meta-analysis was conducted via RevMan 5...
February 8, 2018: Urolithiasis
Elisabeth M H Mathus-Vliegen, Karin van der Vliet, Inge J Wignand-van der Storm, John S Stadwijk
BACKGROUND: Because of its volume, adequate bowel preparation remains problematic in physically unfit patients. OBJECTIVE: This study aimed to compare a small-volume sodium picosulfate/magnesium citrate preparation with a 2-L ascorbic acid-enriched polyethylene glycol solution plus bisacodyl. DESIGN: This study has a noninferiority design, assuming that ascorbic acid-enriched polyethylene glycol solution plus bisacodyl is 70% efficacious in achieving an Ottawa score ≤7 and accepting a difference in success rate of <15% with a target enrollment of 146 patients per group...
February 2018: Diseases of the Colon and Rectum
Juliana Moura Costa, João Bruno Soares
INTRODUCTION: Bowel preparation for colonoscopy and/or colorectal surgery can cause electrolyte imbalances. The risk of electrolyte imbalances seems to be related to the type of bowel cleansing solution, age of patients and comorbidities. CASE REPORT: We report two cases of symptomatic hyponatremia (focal neurological signs and coma) after bowel preparation with sodium picosulfate/magnesium citrate for colonoscopy. In both cases, symptoms related to hyponatremia rapidly disappeared after sodium level correction with intravenous administration of hypertonic saline (3% NaCl)...
November 29, 2017: Acta Médica Portuguesa
Katie M Groom, Anna L David
Fetal growth restriction and related placental pathologies such as preeclampsia, stillbirth, and placental abruption are believed to arise in early pregnancy when inadequate remodeling of the maternal spiral arteries leads to persistent high-resistance and low-flow uteroplacental circulation. The consequent placental ischaemia, reperfusion injury, and oxidative stress are associated with an imbalance in angiogenic/antiangiogenic factors. Many interventions have centered on the prevention and/or treatment of preeclampsia with results pertaining to fetal growth restriction and small-for-gestational-age pregnancy often included as secondary outcomes because of the common pathophysiology...
February 2018: American Journal of Obstetrics and Gynecology
Peng Guo, Qiang Li, Yi-Ping Qi, Lin-Tong Yang, Xin Ye, Huan-Huan Chen, Li-Song Chen
Limited data are available on the sulfur (S)-mediated-alleviation of aluminum (Al)-toxicity in higher plants. Citrus grandis seedlings were irrigated for 18 weeks with 0.5 mM MgSO₄ or 0.5 mM MgSO₄ + 0.5 mM Na₂SO₄, and 0 (-Al) or 1 mM AlCl₃·6H₂O (+Al, Al-toxicity). Under Al-toxicity, S decreased the level of Al in leaves; increased the relative water content (RWC) of roots and leaves, the contents of phosphorus (P), calcium (Ca) and magnesium (Mg) per plant, the dry weights (DW) of roots and shoots, the ratios of root DW/shoot DW, and the Al-induced secretion of citrate from root; and alleviated the Al-induced inhibition of photosynthesis via mitigating the Al-induced decrease of electron transport capacity resulting from the impaired photosynthetic electron transport chain...
December 3, 2017: International Journal of Molecular Sciences
Mustafa Zafer Temiz, Emrah Yuruk, Kasim Ertas, Oguzhan Zengi, Atilla Semercioz
PURPOSE: To investigate whether atorvastatin has favorable effects on urinary metabolic risk factors associated with urolithiasis. METHODS: Sixteen male Sprague-Dawley rats were randomly divided into two groups, and baseline spot and 24-h urine samples were collected. Distilled water and atorvastatin were administered to rats during 4 weeks in the control and atorvastatin groups, respectively. At the end of the experimental procedure, spot and 24-h urine samples were collected again...
February 2018: International Urology and Nephrology
Mahboubeh Yousefi Ghale-Salimi, Maryam Eidi, Nasser Ghaemi, Ramezan Ali Khavari-Nejad
Taraxasterol is one of the important constituents of Taraxacum officinale L. (Compositae) with antioxidant potential. The present study was designed to evaluate and compare the antiurolithiatic effects of taraxasterol and potassium citrate in the ethylene glycol induced urolithiatic rat. Urolithiasis was induced by ammonium chloride and ethylene glycol in adult male rats. Taraxasterol (2, 4 and 8 mg/kg) and potassium citrate (2.5 g/kg) were treated for 33 days by gavage. Then, the animals were anesthetized and weighted and blood, urine, liver and kidney sampling were done...
November 30, 2017: Urolithiasis
Brandon J Teng, Shawn H Song, Jelena N Svircev, Jason A Dominitz, Stephen P Burns
STUDY DESIGN: Retrospective chart audit. OBJECTIVES: To compare adequacy of colonoscopy bowel preparation and diagnostic findings between persons with SCI receiving an extended inpatient bowel preparation and the general population. SETTING: Veterans Affairs Puget Sound Healthcare System, Seattle, WA, USA. METHODS: We reviewed an electronic database of all colonoscopies performed at a tertiary Veterans Affairs medical center between 7/12/13 and 15/10/15...
November 24, 2017: Spinal Cord
Ilvy van Lieshout, Isabelle D Munsterman, Anne M Eskes, Jolanda M Maaskant, René van der Hulst
Background: An effective and tolerable bowel preparation is important to secure quality of colonoscopies. It remains unclear if sodium picosulphate with magnesium citrate (SPMC), which is considered a tolerable bowel preparation agent, is also an effective alternative for polyethylene glycol (PEG) and sodium phosphate (NaP). Aim: The aim of this article is to compare effectiveness of SPMC to PEG and NaP through assessment of quality of bowel cleansing measured by validated tools...
November 2017: United European Gastroenterology Journal
Chandrashekhar Thukral, Sumeet K Tewani, Adam J Lake, Aaron J Shiels, Kathy Geissler, Sara Popejoy, Megan Stafford, Joseph J Vicari
BACKGROUND: Current bowel preparations for colonoscopy include a clear liquid diet (CLD) along with consumption of a laxative. This dietary restriction along with large volume bowel preparations are barriers to compliance and willingness among patients in scheduling screening examinations. The aim of our study was to compare the efficacy and tolerability of a low-volume split dose magnesium citrate bowel preparation in patients on a low-residue diet (LRD) with those on a CLD. METHODS: In this single center, single blinded, randomized controlled trial, patients scheduled for outpatient colonoscopies were assigned to either a CLD or a LRD 1 day before the examination...
November 3, 2017: Journal of Clinical Gastroenterology
Vladimir Kojecky, Jan Matous, Radan Keil, Milan Dastych, Zdena Zadorova, Michal Varga, Radek Kroupa, Jiri Dolina, Miroslav Misurec, Ales Hep, Martin Griva
BACKGROUND & AIMS: The optimal duration of bowel preparation has only been assessed for polyethylene glycol (PEG). The aim of the study was to determine the intervals for achieving a satisfactory quality/tolerability of the preparation using PEG/ascorbic acid (PEGA) and sodium picosulphate/magnesium citrate (SPMC), and to compare them with 4L of PEG. METHODS: A randomized, endoscopist-blinded, multicentre study. The 612 outpatients referred to a colonoscopy, were prepared using PEG, SPMC, PEGA...
November 1, 2017: Digestive and Liver Disease
Zanlin Mai, Xiaoxia Li, Zelin Cui, Wenqi Wu, Yongda Liu, Lili Ou, Yueping Liang, Zhijian Zhao, Yang Liu, Xing Mai, Wei Zhu, Tao Zhang, Chao Cai, Houmeng Yang, Guohua Zeng
BACKGROUND: The aim of the study was to establish reference intervals for 24-h urinary stone risk factors in the healthy Chinese Han population. METHODS: From May 2013 to July 2014, we collected and analyzed 24-h urine samples from healthy adult Han population during a cross-sectional study across China. The protocol for analysis of 24-h urine included volume, pH, oxalate, citrate, sodium, potassium, chloride, calcium, phosphorous, creatinine, urate, magnesium, the ion activity products of calcium oxalate (AP(CaOx) indexs) and calcium phosphate (AP(CaP) indexs)...
November 2, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
Jiarong Zhang, Jian Wei, Dongxu Li, Xiangying Kong, Zed Rengel, Limei Chen, Ye Yang, Xiuming Cui, Qi Chen
Aluminum (Al) toxicity is a key factor limiting plant growth and crop production on acid soils. Increasing the plant Al-detoxification capacity and/or breeding Al-resistant cultivars are a cost-effective strategy to support crop growth on acidic soils. The plasma membrane H(+)-ATPase plays a central role in all plant physiological processes. Changes in the activity of the plasma membrane H(+)-ATPase through regulating the expression and phosphorylation of this enzyme are also involved in many plant responses to Al toxicity...
2017: Frontiers in Plant Science
Kang Chen, Dong Chen, Chuangxin Lan, Xiongfa Liang, Tao Zeng, Jian Huang, Xiaolu Duan, Zhenzhen Kong, Shujue Li, Hans-Göran Tiselius, Alberto Gurioli, Xiaogang Lu, Guohua Zeng, Wenqi Wu
OBJECTIVE: To investigate the impact of green tea on urinary oxalate excretion in healthy male volunteers. MATERIALS AND METHODS: The oxalate concentrations after different brewing times (2-60 min) of different qualities (2-8 g) of green tea were measured in in vitro experiment. In in vivo experiment, the effects on urine composition were assessed in 12 healthy men with an age of 24-29 years. Each subject was requested to collect two 24-h urine samples under normal dietary conditions...
January 2018: International Urology and Nephrology
J Santiago-Moreno, C Castaño, A Toledano-Díaz, M C Esteso, A López-Sebastián, S Villaverde-Morcillo, S G Dávila, M G Gil, E Blesbois
The fertilizing capacity of pure, fresh avian semen may disappear in just half an hour, hindering its successful use in artificial insemination (AI) projects. Longer storage requires the use of infra-physiological temperatures and of semen diluents that help preserve the spermatozoa but that do not interfere with their fertilizing capacity. This study examines the effect on sperm quality of storing red-legged partridge sperm for 3 h at 5°C with 2 different semen extenders: 1) a medium referred to as L&R-84, composed of sodium glutamate, glucose, magnesium acetate, potassium acetate, and polyvinylpyrrolidone, and 2) Lake 7...
September 1, 2017: Poultry Science
Elaine Vo, Nader N Massarweh, Christy Y Chai, Hop S Tran Cao, Nader Zamani, Sherry Abraham, Kafayat Adigun, Samir S Awad
Importance: Surgical site infections (SSIs) after colorectal surgery remain a significant complication, particularly for patients with cancer, because they can delay the administration of adjuvant therapy. A combination of oral antibiotics and mechanical bowel preparation (MBP) is a potential, yet controversial, SSI prevention strategy. Objective: To determine the association of the addition of oral antibiotics to MBP with preventing SSIs in left colon and rectal cancer resections and its association with the timely administration of adjuvant therapy...
February 1, 2018: JAMA Surgery
Poppy Das, Gaurav Gupta, Vinodhini Velu, Rajendra Awasthi, Kamal Dua, Himaja Malipeddi
BACKGROUND: Struvite is one of the most common urinary/kidney stones, composed of magnesium ammonium phosphate (MgNHPO4 ·H2 O). They are also termed as infection stones as these are associated with urinary tract infections. Numerous studies have been carried out to examine the growth and inhibition of struvite stones. OBJECTIVE: This review summarizes various reports on the factors responsible for inducing struvite stones in the kidney and gives a detailed account of studies on inhibition of growth of struvite crystals...
December 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
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