keyword
https://read.qxmd.com/read/38529348/copd-systemic-proteomic-profiles-in-frequent-and-infrequent-exacerbators
#21
JOURNAL ARTICLE
Cesar Jessé Enríquez-Rodríguez, Carme Casadevall, Rosa Faner, Ady Castro-Costa, Sergi Pascual-Guàrdia, Luis Seijó, José Luis López-Campos, Germán Peces-Barba, Eduard Monsó, Esther Barreiro, Borja G Cosío, Alvar Agustí, Joaquim Gea
BACKGROUND: Some patients with COPD suffer frequent exacerbations (FE). We hypothesised that their systemic proteomic profile would be different from that of non-frequent exacerbators (NFE). The objective of the present study was to contrast the systemic proteomic profile in FE versus NFE. As a reference, we also determined the systemic proteomic profile of healthy controls (HC) and COPD patients during an actual episode of exacerbation (AE). METHODS: In the analysis we included 40 clinically stable COPD patients (20 FE and 20 NFE), and 20 HC and 10 AE patients...
March 2024: ERJ Open Research
https://read.qxmd.com/read/38528860/a-mixture-of-mobility-and-meteorological-data-provides-a-high-correlation-with-covid-19-growth-in-an-infection-naive-population-a-study-for-spanish-provinces
#22
JOURNAL ARTICLE
David Conesa, Víctor López de Rioja, Tania Gullón, Adriá Tauste Campo, Clara Prats, Enrique Alvarez-Lacalle, Blas Echebarria
INTRODUCTION: We use Spanish data from August 2020 to March 2021 as a natural experiment to analyze how a standardized measure of COVID-19 growth correlates with asymmetric meteorological and mobility situations in 48 Spanish provinces. The period of time is selected prior to vaccination so that the level of susceptibility was high, and during geographically asymmetric implementation of non-pharmacological interventions. METHODS: We develop reliable aggregated mobility data from different public sources and also compute the average meteorological time series of temperature, dew point, and UV radiance in each Spanish province from satellite data...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38527854/connecting-dementia-risk-loci-to-the-csf-proteome-identifies-pathophysiological-leads-for-dementia
#23
JOURNAL ARTICLE
Lianne M Reus, Iris E Jansen, Betty M Tijms, Pieter Jelle Visser, Niccoló Tesi, Sven J van der Lee, Lisa Vermunt, Carel F W Peeters, Lisa A De Groot, Yanaika S Hok-A-Hin, Alice Chen-Plotkin, David J Irwin, William T Hu, Lieke H Meeter, John C van Swieten, Henne Holstege, Marc Hulsman, Afina W Lemstra, Yolande A L Pijnenburg, Wiesje M van der Flier, Charlotte E Teunissen, Marta Del Campo Milan
Genome-wide association studies have successfully identified many genetic risk loci for dementia, but exact biological mechanisms through which genetic risk factors contribute to dementia remains unclear. Integrating CSF proteomic data with dementia risk loci could reveal intermediate molecular pathways connecting genetic variance to the development of dementia. We tested to what extent effects of known dementia risk loci can be observed in CSF levels of 665 proteins (proximity extension-based (PEA) immunoassays) in a deeply-phenotyped mixed-memory clinic cohort (n=502, mean age (sd) = 64...
March 25, 2024: Brain
https://read.qxmd.com/read/38527232/predictive-model-for-estimating-the-risk-of-epilepsy-after-aneurysmal-subarachnoid-hemorrhage-the-rise-score
#24
JOURNAL ARTICLE
Daniel Campos-Fernandez, Marc Rodrigo-Gisbert, Laura Abraira, Manuel Quintana Luque, Manel Santafé, Sofia Lallana, Elena Fonseca, Manuel Toledo, Darío F Gándara, Fuat Arikan, Alejandro Tomasello, Jacint X Sala Padró, Merce Falip, Pablo López-Ojeda, Andreu Gabarrós, Anna Sánchez, Estevo Santamarina
BACKGROUND AND OBJECTIVES: The occurrence of seizures after aneurysmal subarachnoid hemorrhage (aSAH) is associated with a poorer functional and cognitive prognosis and less favorable quality of life. It would be of value to promptly identify patients at risk of epilepsy to optimize follow-up protocols and design preventive strategies. Our aim was to develop a predictive score to help stratify epilepsy risk in patients with aSAH. METHODS: This is a retrospective, longitudinal study of all adults with aSAH admitted to our center (2012-2021)...
April 23, 2024: Neurology
https://read.qxmd.com/read/38526830/correction-anandamide-and-win-55212-2-afford-protection-in-rat-brain-mitochondria-in-a-toxic-model-induced-by-3-nitropropionic-acid-an-in-vitro-study
#25
Marisol Maya-López, Luis Angel Monsalvo-Maraver, Ana Laura Delgado-Arzate, Carolina I Olivera-Pérez, Mohammed El-Hafidi, Alejandro Silva-Palacios, Omar Medina-Campos, José Pedraza-Chaverri, Michael Aschner, Alexey A Tinkov, Isaac Túnez, Socorro Retana-Márquez, Cecilia Zazueta, Abel Santamaría
No abstract text is available yet for this article.
March 25, 2024: Molecular Neurobiology
https://read.qxmd.com/read/38526024/home-participation-and-personal-and-environmental-factors-in-children-and-adolescents-with-down-syndrome
#26
JOURNAL ARTICLE
Beatriz Helena Brugnaro, Gesica Fernandes, Ana Carolina De Campos, Silvia Letícia Pavão, Luzia Iara Pfeifer, Olaf Kraus de Camargo, Oksana Hlyva, Nelci Adriana Cicuto Ferreira Rocha
AIM: To describe current home participation (frequency, involvement) and caregiver's desire for change in home participation of children and adolescents with Down syndrome, as well as home environmental factors, and to explore the associations of personal and environmental factors with current participation and caregiver's desire for change. METHOD: Eighty-two caregivers (mean age = 45 years 10 months) of children and adolescents with Down syndrome (mean age = 10 years 7 months) were surveyed about the child's home participation and environmental factors using the Participation and Environment Measure-Children and Youth...
March 25, 2024: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/38525414/surgical-oncologic-and-obstetric-outcomes-of-radical-trachelectomy-in-early-stage-cervical-cancer-results-from-a-retrospective-cohort-study-at-brazil-national-cancer-institute
#27
JOURNAL ARTICLE
José Augusto Bellotti, Isabella Gonçalves Gutierres, Yara Lúcia Furtado, Patricia Patury, Juliana de Almeida Figueiredo, Gustavo Guitmann, Rossano Keppler Alvin Fiorelli, Fernanda Campos da Silva
OBJECTIVE: to analyze oncological, obstetrical, and surgical results of young early-stage cervical cancer patients who underwent radical trachelectomy (RT) surgery and wished to maintain their fertility. METHODOLOGY: a retrospective cohort study was carried out concerning cases attended at the Brazilian National Cancer Institute Gynecology Oncology Service. Patients who underwent RT between January 2005 and January 2021 were included. RESULTS: A total of 32 patients with median age of 32 years old, 62...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38524831/technical-and-tactical-evolution-of-the-offensive-team-sequences-in-laliga-between-2008-and-2021-is-spanish-football-now-a-more-associative-game
#28
JOURNAL ARTICLE
Joaquín González-Rodenas, Víctor Moreno-Pérez, Roberto López-Del Campo, Ricardo Resta, Juan Del Coso
The aim of this investigation was to study the technical and tactical evolution of the offensive team sequences in the Spanish football teams from 2008/09 to 2020/21. A comparative analysis including twelve variables related to the development of offensive sequences in 4940 matches was performed from 2008/09 to 2020/21 seasons of the Spanish professional football league (LaLiga). All match observations were recorded using a validated video tracking system. Multilevel linear mixed models were used to examine the differences across seasons, considering the effects of contextual variables...
March 2024: Biology of Sport
https://read.qxmd.com/read/38524806/tell-me-how-much-your-opponent-team-runs-and-i-will-tell-you-how-much-you-should-run-a-predictive-model-applied-to-spanish-high-level-football
#29
JOURNAL ARTICLE
Julen Castellano, Roberto López-Del Campo, Raúl Hileno
The aim of this study was to predict a team's accumulated distance (TotDisTea) and accumulated distance at > 21 km/h (TotDis21Tea) in the Spanish Football First Division. 2,946 team physical performances (out of 3040 possible) during four seasons (from 2016-17 to 2019-20) were analysed. The outcome variables were the TotDisTea and TotDis21Tea when the ball was in play. Eight predictor variables were used: the distance accumulated and accumulated at > 21 km/h by the opponent (TotDisOpp and TotDis21Opp) were registered in km, the effective playing (EffPlaTim) and possession (BalPos) time were recorded in min, match location (MatLoc) had two levels (home and away), match outcome (MatOut) had three levels (lost, drawn, and won), and the teams were grouped in four levels (Champions League, Europa League, remained, and relegation) distinguishing the observed team (TeaLev) and the opponent team (OppLev) in the match...
March 2024: Biology of Sport
https://read.qxmd.com/read/38524724/comparison-of-sociodemographic-and-radiographic-features-in-distal-radio-fracture-treatment-hand-surgeons-versus-non-specialists
#30
JOURNAL ARTICLE
Rafael Bulyk Veiga, Renê Hobi, Ricardo Pereira Marot, Gustavo Zeni Schuroff, Roberto Luiz Sobania, Ivan Killing Kuhn, Ana Lucia Campos Faccioni
Objective:  This study evaluated sociodemographic and radiographic features of patients with distal radial fractures treated at a trauma hospital in southern Brazil, comparing those treated by hand surgery specialists (group 1) and non-specialists (group 2). Methods:  This study consists of a retrospective cohort of 200 patients treated in 2020. After reviewing medical records and radiographs, the following parameters were analyzed: age, gender, trauma mechanism, laterality, associated comorbidities and fractures, fracture classification (AO), radial height, radial inclination, and volar inclination...
February 2024: Revista Brasileira de Ortopedia
https://read.qxmd.com/read/38523365/mucoadhesive-delivery-systems-for-oral-candidiasis-treatment-a-systematic-review-and-meta-analysis
#31
REVIEW
Carolina Yoshi Campos Sugio, Amanda Aparecida Maia Neves Garcia, Klaryssa Akemi de Araujo Kitamoto, Joel Ferreira Santiago Júnior, Simone Soares, Vinicius Carvalho Porto, Vanessa Migliorini Urban, Priscileila Colerato Ferrari, Maria Helena Fernandes, Karin Hermana Neppelenbroek
OBJECTIVES: This systematic review and meta-analysis aimed to evaluate the clinical and mycological effectiveness of mucoadhesives as vehicles for drugs or natural products in the treatment of oral candidiasis. MATERIALS AND METHODS: The search for articles was carried out in the Medline/PubMed, SCOPUS, EMBASE, Web of Science, Cochrane Library, and SciELO databases before August 2023. We selected the studies, extracted the data, evaluated the study quality, graded the evidence, performed the risk of bias, and carried out meta-analysis...
March 24, 2024: Oral Diseases
https://read.qxmd.com/read/38522541/analysis-of-environmental-factors-influence-on-endemic-cholera-risks-in-sub-saharan-africa
#32
JOURNAL ARTICLE
Cristiane D Girotto, Kourosh Behzadian, Anwar Musah, Albert S Chen, Slobodan Djordjevic, Gordon Nichols, Luiza C Campos
The recurring cholera outbreaks in sub-Saharan Africa are of growing concern, especially considering the potential acceleration in the global trend of larger and more lethal cholera outbreaks due to the impacts of climate change. However, there is a scarcity of evidence-based research addressing the environmental and infrastructure factors that sustain cholera recurrence in Africa. This study adopts a statistical approach to investigate over two decades of endemic cholera outbreaks and their relationship with five environmental factors: water provision, sanitation provision, raising temperatures, increased rainfall and GDP...
March 22, 2024: Science of the Total Environment
https://read.qxmd.com/read/38521782/potential-use-of-sludge-from-el-ferrol-bay-chimbote-peru-for-the-production-of-lipids-in-the-culture-of-scenedesmus-acutus-meyen-1829
#33
JOURNAL ARTICLE
Fernando Merino, Sorayda Mendoza, Juan Carhuapoma-Garay, Luis Campoverde-Vigo, Yolanda P Huamancondor-Paz, Yudith Choque-Quispe, Dianeth Buleje Campos, David Choque-Quispe, Liliana Rodriguez-Cardenas, Guillermo B Saldaña-Rojas, Rómulo E Loayza-Aguilar, Gustavo E Olivos-Ramirez
Despite the extensive development of microalgae biotechnology, it still requires new methodologies to lower production costs, especially in the field of biofuel production. Therefore, innovative methods that facilitate operations and enable cost-effective production are important in driving this industry. In this study, we propose a new low-cost and easy-to-use procedure, addressed to the generation of a culture medium for Scenedesmus acutus. The medium was obtained by thermal reduction of a sludge sample from El Ferrol Bay (Chimbote, Peru), whereby we obtained an aqueous medium...
March 23, 2024: Scientific Reports
https://read.qxmd.com/read/38521444/review-evidence-supporting-the-preparation-for-oxidative-stress-pos-strategy-in-animals-in-their-natural-environment
#34
REVIEW
Maximiliano Giraud-Billoud, Daniel C Moreira, Marina Minari, Aleksandra Andreyeva, Élida G Campos, Juan M Carvajalino-Fernández, Aleksandra Istomina, Basile Michaelidis, Cuijuan Niu, Yonggang Niu, Luciana Ondei, Marko Prokić, Georgina A Rivera-Ingraham, Debadas Sahoo, Alexandra Staikou, Janet M Storey, Kenneth B Storey, Israel A Vega, Marcelo Hermes-Lima
Hypometabolism is a common strategy employed by resilient species to withstand environmental stressors that would be life-threatening for other organisms. Under conditions such as hypoxia/anoxia, temperature and salinity stress, or seasonal changes (e.g. hibernation, estivation), stress-tolerant species down-regulate pathways to decrease energy expenditures until the return of less challenging conditions. However, it is with the return of these more favorable conditions and the reactivation of basal metabolic rates that a strong increase of reactive oxygen and nitrogen species (RONS) occurs, leading to oxidative stress...
March 21, 2024: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
https://read.qxmd.com/read/38520634/alcohol-drinking-impacts-on-adiposity-and-steatotic-liver-disease-concurrent-effects-on-metabolic-pathways-and-cardiovascular-risks
#35
REVIEW
Diego Martínez-Urbistondo, Nuria Perez-Diaz-Del-Campo, Manuel F Landecho, J Alfredo Martínez
PURPOSE OF REVIEW: This integrative search aimed to provide a scoping overview of the relationships between the benefits and harms of alcohol drinking with cardiovascular events as associated to body fat mass and fatty liver diseases, as well as offering critical insights for precision nutrition research and personalized medicine implementation concerning cardiovascular risk management associated to ethanol consumption. RECENT FINDINGS: Frequent alcohol intake could contribute to a sustained rise in adiposity over time...
March 23, 2024: Current Obesity Reports
https://read.qxmd.com/read/38520430/identifying-subgroups-of-youth-suicide-decedents-based-on-clinical-profiles-of-psychiatric-and-medical-diagnoses-a-latent-class-analysis
#36
JOURNAL ARTICLE
Amanda J Thompson, Christopher C Henrich, Danielle L Steelesmith, Jennifer Hughes, Donna Ruch, Jeffrey A Bridge, John V Campo, Cynthia A Fontanella
PURPOSE: To identify risk subgroups of youth suicide decedents using demographic and clinical psychiatric and medical diagnostic profiles to inform tailored youth suicide prevention efforts. METHODS: This study linked Ohio Medicaid and death certificate data for Medicaid enrolled youth aged 8-25 years who died by suicide between January 1, 2010, and December 31, 2020 (N = 511). Latent class analysis was used to identify distinct clinical risk subgroups. RESULTS: Three latent classes were identified...
March 21, 2024: Journal of Adolescent Health
https://read.qxmd.com/read/38519918/the-oral-health-impact-profile-and-well-being-on-mothers-and-preschool-children
#37
JOURNAL ARTICLE
Bianca Núbia Souza Silva, Lucas Arrais de Campos, João Maroco, Juliana Alvares Duarte Bonini Campos
OBJECTIVES: to verify the contribution of mothers' oral health impact profile to their children's oral health profile and the contribution of mothers' well-being and the caries index (dmft) to children's well-being. METHODS: This is a cross-sectional observational study. Mothers and pre-school children enrolled in public schools in the municipality of Araraquara-SP took part. The Oral Health Impact Profile Questionnaire (OHIP-14), Satisfaction with Life Scale (SWLS), Early Childhood Oral Health Impact Scale (ECOHIS) and the Autoquestionnaire Qualité de Vie Enfant Imagé (AUQEI) were used...
March 22, 2024: BMC Oral Health
https://read.qxmd.com/read/38518867/clean-label-products-factors-affecting-liking-and-acceptability-by-portuguese-older-adults
#38
JOURNAL ARTICLE
Ana Campos Fernandes, Cecília Morais, Bela Franchini, Bárbara Pereira, Olívia Pinho, Luís Miguel Cunha
Consumers are preferring more "natural" foods, made of "healthier" and "familiar" components - the "clean-label" trend. As the population ages, understanding the older adult consumer segment becomes increasingly important. This study aims to identify the factors influencing the acceptability and liking of clean-label products in older adults living in the community. A convenience sample of 100 older adults was used for this cross-sectional study. Socio-demographic data, health status, independence level, lifestyle characteristics, nutritional status, and food and nutrient intake data were collected...
March 20, 2024: Appetite
https://read.qxmd.com/read/38518607/genipin-crosslinking-promotes-biomechanical-reinforcement-and-pro-regenerative-macrophage-polarization-in-bioartificial-tubular-substitutes
#39
JOURNAL ARTICLE
Jone Berasain, Paula Ávila-Fernández, Rocío Cárdenas-Pérez, Antoni Ignasi Cànaves-Llabrés, Miguel Etayo-Escanilla, Miguel Alaminos, Víctor Carriel, Óscar Darío García-García, Jesús Chato-Astrain, Fernando Campos
Traumatic nerve injuries are nowadays a significant clinical challenge and new substitutes with adequate biological and mechanical properties are in need. In this context, fibrin-agarose hydrogels (FA) have shown the possibility to generate tubular scaffolds with promising results for nerve repair. However, to be clinically viable, these scaffolds need to possess enhanced mechanical properties. In this line, genipin (GP) crosslinking has demonstrated to improve biomechanical properties with good biological properties compared to other crosslinkers...
March 20, 2024: Biomedicine & Pharmacotherapy
https://read.qxmd.com/read/38517597/analysis-of-26-str-loci-powerplex%C3%A2-fusion-6c-system-in-a-mestizo-population-from-mexico-city
#40
JOURNAL ARTICLE
Mauro López-Armenta, María Elizbeth Álvarez-Sánchez, Carolina León-Campos, Blanca Zoila Gonzalez-Sobrino, Héctor Rangel-Villalobos, José Francisco Muñoz-Valle, Astrid Desireé Sánchez-Méndez, José Alonso Aguilar-Velázquez
BACKGROUND: Short tandem repeats (STRs) are the most widely used genetic markers in forensic genetics. Therefore, it is essential to document genetic population data of new kits designed for human identification purposes to enable laboratories to use these genetic systems to interpret and solve forensic casework. However, in Mexico, there are no studies with the PowerPlex Fusion 6C System, which includes 26 STRs (23 autosomal STRs and 3 Y-STRs). METHODS AND RESULTS: 600 DNA samples from Mexico City were subjected to genotyping using the PowerPlex Fusion 6C System...
March 22, 2024: Molecular Biology Reports
keyword
keyword
37016
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.