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https://www.readbyqxmd.com/read/28212193/the-elusive-pursuit-of-work-life-balance
#1
Cindy Peternelj-Taylor
No abstract text is available yet for this article.
January 2017: Journal of Forensic Nursing
https://www.readbyqxmd.com/read/28212175/advances-in-epilepsy-gene-discovery-and-implications-for-epilepsy-diagnosis-and-treatment
#2
Joseph D Symonds, Sameer M Zuberi, Michael R Johnson
PURPOSE OF REVIEW: Epilepsy genetics is shifting from the academic pursuit of gene discovery to a clinical discipline based on molecular diagnosis and stratified medicine. We consider the latest developments in epilepsy genetics and review how gene discovery in epilepsy is influencing the clinical classification of epilepsy and informing new therapeutic approaches and drug discovery. RECENT FINDINGS: Recent studies highlighting the importance of mutation in GABA receptors, NMDA receptors, potassium channels, G-protein coupled receptors, mammalian target of rapamycin pathway and chromatin remodeling are discussed...
February 15, 2017: Current Opinion in Neurology
https://www.readbyqxmd.com/read/28210790/factors-influencing-the-success-of-anterior-cruciate-ligament-repair-with-dynamic-intraligamentary-stabilisation
#3
Anna M Krismer, Lampros Gousopoulos, Sandro Kohl, Atesch Ateschrang, Hendrik Kohlhof, Sufian S Ahmad
PURPOSE: Primary repair of the anterior cruciate ligament (ACL) has regained interest of clinicians with recent development of novel repair techniques. Dynamic intraligamentary stabilisation was introduced in an attempt to promote healing by shielding cyclic loads acting upon the ACL during the healing phase. The aim of this study was to identify negative factors likely to influence success of this procedure. METHODS: Between 2009 and 2014, 264 patients with an acute ACL rupture undergoing dynamic intraligamentary stabilisation were included in this study...
February 17, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28209236/epithelial-downgrowth-report-of-2-cases-diagnosed-by-ocular-biopsy
#4
REVIEW
Hershel R Patel, Curtis E Margo
Epithelial downgrowth is an uncommon complication of ocular surgery or adverse consequence of accidental trauma, caused by surface squamous epithelium that has gained access to the inner compartments of the eye. Once embedded in the eye, squamous epithelium spreads over contiguous structures, interfering with normal aqueous outflow and vision. The pursuit of improved therapies is ongoing, but the greatest chance of preventing blindness is with early recognition. Two cases of epithelial downgrowth diagnosed from a corneal button and an iris biopsy are presented to familiarize pathologists with this disorder...
February 2017: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/28208834/in%C3%A2-pursuit%C3%A2-of%C3%A2-vitamin%C3%A2-d%C3%A2-in%C3%A2-plants
#5
Lucinda J Black, Robyn M Lucas, Jill L Sherriff, Lars Olof Björn, Janet F Bornman
Vitamin D deficiency is a global concern. Much research has concentrated on the endogenous synthesis of vitamin D in human skin following exposure to ultraviolet-B radiation (UV-B, 280-315 nm). In many regions of the world there is insufficient UV-B radiation during winter months for adequate vitamin D production, and even when there is sufficient UV-B radiation, lifestyles and concerns about the risks of sun exposure may lead to insufficient exposure and to vitamin D deficiency. In these situations, dietary intake of vitamin D from foods or supplements is important for maintaining optimal vitamin D status...
February 13, 2017: Nutrients
https://www.readbyqxmd.com/read/28202571/temporal-dynamics-of-retinal-and-extraretinal-signals-in-the-fefsem-during-smooth-pursuit-eye-movements
#6
Leah Bakst, Jerome Fleuriet, Michael J Mustari
Neurons in the smooth eye movement subregion of the Frontal Eye Field (FEFsem) are known to play an important role in voluntary smooth pursuit eye movements. Underlying this function are projections to parietal and prefrontal visual association areas and subcortical structures, all known to play vital, but differing roles in the execution of smooth pursuit. Additionally, the FEFsem has been shown to carry a diverse array of signals (e.g. eye velocity, acceleration, gain control). We hypothesized that distinct subpopulations of FEFsem neurons subserve these diverse functions and projections, and that the relative weights of retinal and extraretinal signals could form the basis for categorization of units...
February 15, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28199307/arrays-of-horizontal-carbon-nanotubes-of-controlled-chirality-grown-using-designed-catalysts
#7
Shuchen Zhang, Lixing Kang, Xiao Wang, Lianming Tong, Liangwei Yang, Zequn Wang, Kuo Qi, Shibin Deng, Qingwen Li, Xuedong Bai, Feng Ding, Jin Zhang
The semiconductor industry is increasingly of the view that Moore's law-which predicts the biennial doubling of the number of transistors per microprocessor chip-is nearing its end. Consequently, the pursuit of alternative semiconducting materials for nanoelectronic devices, including single-walled carbon nanotubes (SWNTs), continues. Arrays of horizontal nanotubes are particularly appealing for technological applications because they optimize current output. However, the direct growth of horizontal SWNT arrays with controlled chirality, that would enable the arrays to be adapted for a wider range of applications and ensure the uniformity of the fabricated devices, has not yet been achieved...
February 15, 2017: Nature
https://www.readbyqxmd.com/read/28199101/fungal-identification-using-molecular-tools-a-primer-for-the-natural-products-research-community
#8
Huzefa A Raja, Andrew N Miller, Cedric J Pearce, Nicholas H Oberlies
Fungi are morphologically, ecologically, metabolically, and phylogenetically diverse. They are known to produce numerous bioactive molecules, which makes them very useful for natural products researchers in their pursuit of discovering new chemical diversity with agricultural, industrial, and pharmaceutical applications. Despite their importance in natural products chemistry, identification of fungi remains a daunting task for chemists, especially those who do not work with a trained mycologist. The purpose of this review is to update natural products researchers about the tools available for molecular identification of fungi...
February 15, 2017: Journal of Natural Products
https://www.readbyqxmd.com/read/28198465/fatigue-related-impairments-in-oculomotor-control-are-prevented-by-norepinephrine-dopamine-reuptake-inhibition
#9
Charlotte J W Connell, Benjamin Thompson, Jason Turuwhenua, Alexa Srzich, Nicholas Gant
Fatigue-induced reductions in saccade velocity have been reported following acute, prolonged exercise. Interestingly, the detrimental impact of fatigue on oculomotor control can be prevented by a moderate dose of caffeine. This effect may be related to central catecholamine upregulation via caffeine's action as an adenosine antagonist. To test this hypothesis, we compared the protective effect of caffeine on oculomotor control post-exercise to that of a norepinephrine-dopamine reuptake inhibitor. Within a placebo-controlled crossover design, 12 cyclists consumed placebo, caffeine or a norepinephrine-dopamine reuptake inhibitor (bupropion) during 180 minutes of stationary cycling...
February 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28195951/assessment-of-oculomotor-function-in-patients-with-postconcussion-syndrome-a-systematic-review
#10
Foad Taghdiri, Brenda Varriano, Maria Carmela Tartaglia
BACKGROUND: Concussion and its associated sequel, postconcussion syndrome (PCS), have a debilitating impact on the lives of concussed patients. However, a diagnostic biomarker for this condition is lacking. Recently, there has been a surge of interest in using oculomotor function testing as an objective assessment of patients with PCS. OBJECTIVES: To systematically synthesize, appraise, and summarize all published empirical studies that have assessed alteration of oculomotor functions in patients with PCS...
February 10, 2017: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/28195652/identification-of-the-anti-mycobacterial-functional-properties-of-piperidinol-derivatives
#11
Collette S Guy, Esther Tichauer, Gemma L Kay, Daniel J Phillips, Trisha L Bailey, James Harrison, Christopher M Furze, Andrew D Millard, Matthew I Gibson, Mark J Pallen, Elizabeth Fullam
BACKGROUND AND PURPOSE: Tuberculosis (TB) remains a major global health threat and is now the leading cause of death from a single infectious agent worldwide. The current TB drug regimen is inadequate and new anti-tubercular agents are urgently required to be able to successfully combat the increasing prevalence of drug-resistant TB. The purpose of this study was to investigate a piperidinol compound derivative that is highly active against the Mycobacterium tuberculosis bacillus. EXPERIMENTAL APPROACH: The antibacterial properties of the piperidinol compound and its corresponding bis-Mannich base analogue were evaluated against Mycobacterium smegmatis and Gram-negative organisms...
February 14, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28195427/oculomotor-deficits-in-spinocerebellar-ataxia-type-3-potential-biomarkers-of-preclinical-detection-and-disease-progression
#12
Chao Wu, Ding-Bang Chen, Li Feng, Xiang-Xue Zhou, Ji-Wei Zhang, Hua-Jing You, Xiu-Ling Liang, Zhong Pei, Xun-Hua Li
AIMS: To detect specific oculomotor deficits in preclinical stage of spinocerebellar ataxia type 3 (SCA3) and evaluate whether these abnormalities prove useful as potential biomarkers of disease progression. METHODS: A Chinese cohort of 56 patients with SCA3, including 12 preclinical carriers of SCA3 (pre-SCA3) and 44 manifest SCA3, and 26 healthy control individuals were recruited. We performed a detailed investigation on central oculomotor performance including fixation, gaze, smooth pursuit, prosaccade, and antisaccade using video-oculography...
February 13, 2017: CNS Neuroscience & Therapeutics
https://www.readbyqxmd.com/read/28192642/theoretical-rationalization-for-reduced-charge-recombination-in-bulky-carbazole-based-sensitizers-in-solar-cells
#13
Yaowarat Surakhot, Viktor Laszlo, Chirawat Chitpakdee, Vinich Promarak, Taweesak Sudyoadsuk, Nawee Kungwan, Tim Kowalczyk, Stephan Irle, Siriporn Jungsuttiwong
The search for greater efficiency in organic dye-sensitized solar cells (DSCs) and in their perovskite cousins is greatly aided by a more complete understanding of the spectral and morphological properties of the photoactive layer. This investigation resolves a discrepancy in the observed photoconversion efficiency (PCE) of two closely related DSCs based on carbazole-containing D-π-A organic sensitizers. Detailed theoretical characterization of the absorption spectra, dye adsorption on TiO2 , and electronic couplings for charge separation and recombination permit a systematic determination of the origin of the difference in PCE...
February 13, 2017: Journal of Computational Chemistry
https://www.readbyqxmd.com/read/28191910/the-rhetorical-use-of-random-sampling-crafting-and-communicating-the-public-image-of-polls-as-a-science-1935-1948
#14
Dominic Lusinchi
The scientific pollsters (Archibald Crossley, George H. Gallup, and Elmo Roper) emerged onto the American news media scene in 1935. Much of what they did in the following years (1935-1948) was to promote both the political and scientific legitimacy of their enterprise. They sought to be recognized as the sole legitimate producers of public opinion. In this essay I examine the, mostly overlooked, rhetorical work deployed by the pollsters to publicize the scientific credentials of their polling activities, and the central role the concept of sampling has had in that pursuit...
February 13, 2017: Journal of the History of the Behavioral Sciences
https://www.readbyqxmd.com/read/28188201/a-day-of-immersive-physiology-experiments-increases-knowledge-and-excitement-towards-physiology-and-scientific-careers-in-native-american-students
#15
Bryan K Becker, Alicia M Schiller, Irving H Zucker, Eric A Eager, Liliana P Bronner, Maurice Godfrey
Underserved minority groups are disproportionately absent from the pursuit of careers in science, technology, engineering, and mathematics (STEM) fields. One such underserved population, Native Americans, are particularly underrepresented in STEM fields. Although recent advocacy and outreach designed toward increasing minority involvement in health care-related occupations have been mostly successful, little is known about the efficacy of outreach programs in increasing minority enthusiasm toward careers in traditional scientific professions...
March 1, 2017: Advances in Physiology Education
https://www.readbyqxmd.com/read/28187894/improving-recovery-of-ecg-signal-with-deterministic-guarantees-using-split-signal-for-multiple-supports-of-matching-pursuit-ss-msmp-algorithm
#16
Israa Shaker Tawfic, Sema Koc Kayhan
Compressed sensing (CS) is a new field used for signal acquisition and design of sensor that made a large drooping in the cost of acquiring sparse signals. In this paper, new algorithms are developed to improve the performance of the greedy algorithms. In this paper, a new greedy pursuit algorithm, SS-MSMP (Split Signal for Multiple Support of Matching Pursuit), is introduced and theoretical analyses are given. The SS-MSMP is suggested for sparse data acquisition, in order to reconstruct analog and efficient signals via a small set of general measurements...
February 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28187157/distinct-eye-movement-patterns-enhance-dynamic-visual-acuity
#17
Dimitrios J Palidis, Pearson A Wyder-Hodge, Jolande Fooken, Miriam Spering
Dynamic visual acuity (DVA) is the ability to resolve fine spatial detail in dynamic objects during head fixation, or in static objects during head or body rotation. This ability is important for many activities such as ball sports, and a close relation has been shown between DVA and sports expertise. DVA tasks involve eye movements, yet, it is unclear which aspects of eye movements contribute to successful performance. Here we examined the relation between DVA and the kinematics of smooth pursuit and saccadic eye movements in a cohort of 23 varsity baseball players...
2017: PloS One
https://www.readbyqxmd.com/read/28183399/efficacy-of-a-randomized-controlled-self-regulation-based-physical-activity-intervention-for-chronic-fatigue-mediation-effects-of-physical-activity-progress-and-self-regulation-skills
#18
M M Marques, V de Gucht, I Leal, S Maes
OBJECTIVE: Examine the medium-term effects of a brief physical activity (PA) self-regulation (SR) based intervention (4-STEPS program) for chronic fatigue, and explore the mediating effects of PA related variables and SR skills. METHODS: A two-arm randomized controlled trial (Usual Care vs 4-STEPS) was carried out. The 4-STEPS program consisted of Motivational Interviewing and SR-skills training. Fatigue severity (primary outcome) and impact, PA, health-related quality of life (HrQoL), and somatic and psychological distress were assessed at baseline, post-treatment (12weeks) and 12months follow-up...
March 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28182482/the-attribution-of-navigational-and-goal-directed-agency-in-dogs-canis-familiaris-and-human-toddlers-homo-sapiens
#19
Tibor Tauzin, Andor Csík, Kata Lovas, György Gergely, József Topál
Both human infants and nonhuman primates can recognize unfamiliar entities as instrumental agents ascribing to them goals and efficiency of goal-pursuit. This competence relies on movement cues indicating distal sensitivity to the environment and choice of efficient goal-approach. Although dogs' evolved sensitivity to social cues allow them to recognize humans as communicative agents, it remains unclear whether they have also evolved a basic concept of instrumental agency. We used a preferential object-choice procedure to test whether adult pet dogs and human toddlers can identify unfamiliar entities as agents based on different types of movement cues that specify different levels of agency...
February 2017: Journal of Comparative Psychology
https://www.readbyqxmd.com/read/28180034/surrogate-gas-prediction-model-as-a-proxy-for-%C3%AE-14-c-based-measurements-of-fossil-fuel-co2
#20
Kevin J Coakley, John B Miller, Stephen A Montzka, Colm Sweeney, Ben R Miller
The measured (14)C:(12)C isotopic ratio of atmospheric CO2 (and its associated derived Δ(14)C value) is an ideal tracer for determination of the fossil fuel derived CO2 enhancement contributing to any atmospheric CO2 measurement (Cff ). Given enough such measurements, independent top-down estimation of US fossil fuel-CO2 emissions should be possible. However, the number of Δ(14)C measurements is presently constrained by cost, available sample volume, and availability of mass spectrometer measurement facilities...
June 27, 2016: Journal of Geophysical Research. Atmospheres: JGR
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