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https://www.readbyqxmd.com/read/28329427/what-drives-perceived-work-intensity-in-neonatal-intensive-care-units-empirical-evidence-from-a-longitudinal-study
#1
Sandra Sülz, Kristina Langhammer, Michael Becker-Peth, Bernhard Roth
AIM: To investigate the drivers of perceived work intensity among neonatal intensive care unit nurses. BACKGROUND: The consequences of high work intensity have been studied extensively, yet setting-specific drivers have received less attention. DESIGN: Prospective, longitudinal and monocentric study design. METHODS: The study combined data from standardized diary surveys and passive observations of study nurses. Data were collected over a period of six months in 2015...
March 22, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28327235/is-there-an-alternative-explanation-to-the-evolutionary-account-for-financial-and-prosocial-biases-in-favor-of-attractive-individuals
#2
Junhua Dang
All three critical points of the evolutionary explanation proposed by Maestripieri et al. may not withstand close scrutiny. Instead, there should be an alternative explanation that has nothing to do with genetic continuity, but stresses the rewarding property of attractiveness that results mainly from sociocultural value assignment and sexual experience pursuit.
January 2017: Behavioral and Brain Sciences
https://www.readbyqxmd.com/read/28324743/visual-tracking-hot-pursuit-with-tiny-eyes
#3
Eric J Warrant
Flying insect predators intercept their aerial prey with deadly precision. New research reveals that a tiny robber fly, with a brain smaller than a pinhead, achieves this using the same visual mechanism that we ourselves employ to catch a passing ball.
March 20, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28324167/efficacy-and-safety-of-golimumab-52-week-maintenance-therapy-in-japanese-patients-with-moderate-to-severely-active-ulcerative-colitis-a-phase-3-double-blind-randomized-placebo-controlled-study-pursuit-j-study
#4
Toshifumi Hibi, Yuya Imai, Asako Senoo, Kentaro Ohta, Yoshifumi Ukyo
BACKGROUND: The global phase 3 studies of golimumab [PURSUIT-SC and PURSUIT-maintenance (M)], an anti-tumor necrosis factor-α (anti-TNFα) antibody, have demonstrated clinical efficacy and safety as induction and maintenance therapies in patients with moderate to severely active ulcerative colitis (UC). This study aimed to evaluate the efficacy and safety of golimumab as maintenance therapy in the Japanese population. METHODS: In this phase 3, double-blind (DB), placebo-controlled, parallel group, randomized withdrawal study, 144 Japanese patients with moderately to severely active UC received golimumab doses of 200 mg (at week 0) and 100 mg (at week 2) subcutaneously during the 6-week open-label induction phase...
March 21, 2017: Journal of Gastroenterology
https://www.readbyqxmd.com/read/28322981/imaging-genetics-in-autism-spectrum-disorders-linking-genetics-and-brain-imaging-in-the-pursuit-of-the-underlying-neurobiological-mechanisms
#5
REVIEW
Marc Fakhoury
Autism spectrum disorders (ASD) include a wide range of heterogeneous neurodevelopmental conditions that affect an individual in several aspects of social communication and behavior. Recent advances in molecular genetic technologies have dramatically increased our understanding of ASD etiology through the identification of several autism risk genes, most of which serve important functions in synaptic plasticity and protein synthesis. However, despite significant progress in this field of research, the characterization of the neurobiological mechanisms by which common genetic risk variants might operate to give rise to ASD symptomatology has proven to be far more difficult than expected...
March 16, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28322886/high-gamma-oscillations-in-the-motor-cortex-during-visuo-motor-coordination-a-tacs-interferential-study
#6
E Santarnecchi, A Biasella, E Tatti, A Rossi, D Prattichizzo, S Rossi
BACKGROUND: While the role of beta (∼20Hz), theta (∼5Hz) and alpha (∼10Hz) oscillations in the motor areas have been repeatedly associated with defined properties of motor performance, the investigation of gamma (∼40-90Hz) oscillatory activity is a more recent and still not fully understood component of motor control physiology, despite its potential clinical relevance for motor disorders. OBJECTIVE/HYPOTHESIS: we have implemented an online neuromodulation paradigm based on transcranial alternating current stimulation (tACS) of the dominant motor cortex during a visuo-motor coordination task...
March 17, 2017: Brain Research Bulletin
https://www.readbyqxmd.com/read/28322324/high-temperature-near-field-nanothermomechanical-rectification
#7
Mahmoud Elzouka, Sidy Ndao
Limited performance and reliability of electronic devices at extreme temperatures, intensive electromagnetic fields, and radiation found in space exploration missions (i.e., Venus &Jupiter planetary exploration, and heliophysics missions) and earth-based applications requires the development of alternative computing technologies. In the pursuit of alternative technologies, research efforts have looked into developing thermal memory and logic devices that use heat instead of electricity to perform computations...
March 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28320684/the-overcomplete-dictionary-based-directional-estimation-model-and-nonconvex-reconstruction-methods
#8
Leping Lin, Fang Liu, Licheng Jiao, Shuyuan Yang, Hongxia Hao
In this paper, it is proposed the directional estimation model on the overcomplete dictionary, which bridges the compressed measurements of the image blocks and the directional structures of the dictionary. In the model, it is established the analytical method to estimate the structure type of a block as either smooth, single-oriented, or multioriented. Furthermore, the structures of each type of blocks are described by the structured subdictionaries. Then based on the obtained estimations and the constrains on the sparse dictionaries, the original image will be estimated...
March 10, 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/28320678/reinforced-robust-principal-component-pursuit
#9
Pratik Prabhanjan Brahma, Yiyuan She, Shijie Li, Jiade Li, Dapeng Wu
High-dimensional data present in the real world is often corrupted by noise and gross outliers. Principal component analysis (PCA) fails to learn the true low-dimensional subspace in such cases. This is the reason why robust versions of PCA, which put a penalty on arbitrarily large outlying entries, are preferred to perform dimension reduction. In this paper, we argue that it is necessary to study the presence of outliers not only in the observed data matrix but also in the orthogonal complement subspace of the authentic principal subspace...
March 14, 2017: IEEE Transactions on Neural Networks and Learning Systems
https://www.readbyqxmd.com/read/28319111/volumetric-two-photon-imaging-of-neurons-using-stereoscopy-vtwins
#10
Alexander Song, Adam S Charles, Sue Ann Koay, Jeff L Gauthier, Stephan Y Thiberge, Jonathan W Pillow, David W Tank
Two-photon laser scanning microscopy of calcium dynamics using fluorescent indicators is a widely used imaging method for large-scale recording of neural activity in vivo. Here, we introduce volumetric two-photon imaging of neurons using stereoscopy (vTwINS), a volumetric calcium imaging method that uses an elongated, V-shaped point spread function to image a 3D brain volume. Single neurons project to spatially displaced 'image pairs' in the resulting 2D image, and the separation distance between projections is proportional to depth in the volume...
March 20, 2017: Nature Methods
https://www.readbyqxmd.com/read/28318840/self-reported-sleep-disturbances-associated-with-procedural-learning-impairment-in-adolescents-at-ultra-high-risk-for-psychosis
#11
Jessica R Lunsford-Avery, Derek J Dean, Vijay A Mittal
Sleep disturbance contributes to impaired procedural learning in schizophrenia, yet little is known about this relationship prior to psychosis onset. Adolescents at ultra high-risk (UHR; N=62) for psychosis completed the Pittsburgh Sleep Quality Index (PSQI) and a procedural learning task (Pursuit Rotor). Increased self-reported problems with sleep latency, efficiency, and quality were associated with impaired procedural learning rate. Further, within-sample comparisons revealed that UHR youth reporting better sleep displayed a steeper learning curve than those with poorer sleep...
March 16, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28318431/the-pursuit-of-romantic-alternatives-online-social-media-friends-as-potential-romantic-alternatives
#12
Irum Saeed Abbasi, Nawal G Alghamdi
What causes some marriages to stand the test of time while others fail? Marital commitment is the key force underlying the stability, quality, and longevity of the romantic relationship. Commitment is strengthened in the presence of marital satisfaction, the absence of alternative attractions, and steady investments made in the relationship. Commitment is also a consequence of increasing dependence such that when partners are emotionally engaged with their virtual connections, their dependence on their significant other weakens resulting in low commitment...
March 20, 2017: Journal of Sex & Marital Therapy
https://www.readbyqxmd.com/read/28318305/on-demand-driver-vigilance-enhancement-without-explicit-drowsiness-detection-further-analysis-of-the-pilot-study-results
#13
R Michael Van Auken, Brad K Hagoski, Dean P Chiang, Shane Chang
OBJECTIVE: A new active safety concept that engages the driver's psychosensory pain-processing mechanism to automatically trigger vigilance enhancement on-demand was proposed in Chang ( 2012 ). This concept is based on the hypothesis that a human's pain threshold will decline as he/she becomes drowsy, consequently triggering the vigilance enhancer. The objective of this pilot study was to develop methods to test this hypothesis, the results of which could lead to further refinement of the hypothesis and methods, with the ultimate goal of developing new active safety concepts that exploit the driver's endogenous psychosensory pain-processing mechanisms...
March 20, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28317390/failing-to-protect-humanitarian-workers-lessons-from-britain-and-voluntary-aid-detachments-in-the-second-world-war
#14
Amol A Verma
This paper draws on official records of international and British organizations, newspaper reports, and volunteer memoirs to study the failure to protect humanitarian workers in the Second World War. The Second World War saw a significant expansion in the use of air warfare and flying missiles and these technological advances posed a grave threat to civilians and humanitarian workers. In this context, the International Committee of the Red Cross advocated unsuccessfully to restrict air warfare and create safe hospital zones...
March 19, 2017: Medicine, Conflict, and Survival
https://www.readbyqxmd.com/read/28317086/process-evaluation-of-a-randomized-controlled-trial-of-group-support-psychotherapy-for-depression-treatment-among-people-with-hiv-aids-in-northern-uganda
#15
Etheldreda Nakimuli-Mpungu, Kizito Wamala, James Okello, Sheila Ndyanabangi, Steve Kanters, Ramin Mojtabai, Jean B Nachega, Edward J Mills, Seggane Musisi
We describe the process evaluation for a randomized controlled trial that compared group support psychotherapy (GSP) with group HIV education for treatment of depression among people with HIV. Process data were obtained using mixed methods. Variables evaluated were indicators of feasibility and acceptability; causal mediating processes and contextual influences. GSP was feasible and acceptable. Potential mediating variables between GSP and reduction of depression were improved emotional and social support, better coping strategies, and pursuit of livelihoods...
March 19, 2017: Community Mental Health Journal
https://www.readbyqxmd.com/read/28316422/validation-of-romanowsky-staining-as-a-novel-screening-test-for-the-detection-of-faecal-cryptosporidial-oocysts
#16
A P S Brar, N K Sood, L D Singla, P Kaur, K Gupta, B S Sandhu
Cryptosporidiosis is an emerging waterborne protozoan disease and one of the major causes of neonatal diarrhea in humans and animals. But the disease remains under diagnosed due to lack of availability of special stains in majority of laboratories at primary health centers. Therefore, it requires a rapid screening test for routine diagnosis in conventional laboratory set up. In this pursuit, the present study was planned. During this study, fecal samples from 100 representative animals randomly selected from 17 out breaks of bovine calf diarrhea, were stained with modified Ziehl Neelsen staining (mZN) and Leishman's stain to demonstrate cryptosporidial oocysts and for routine fecal examination, respectively...
March 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/28315810/trappings-of-femininity-a-test-of-the-beauty-as-currency-hypothesis-in-shaping-college-women-s-gender-activism
#17
Rachel M Calogero, Tracy L Tylka, Lois C Donnelly, Amber McGetrick, Andrea Medrano Leger
This study investigated whether believing beauty is a primary currency for women operates as an antecedent force in the relation between self-objectification and gender activism. Ninety-four ethnically diverse women attending a small liberal arts college in the southeastern United States completed the study questionnaires online for course credit. Preliminary results demonstrated beauty as currency belief, self-objectification, and support for the gender status quo were negatively associated with gender activism...
March 15, 2017: Body Image
https://www.readbyqxmd.com/read/28315412/engineering-bacterial-translation-initiation-do-we-have-all-the-tools-we-need
#18
REVIEW
Justin Vigar, Hans-Joachim Wieden
BACKGROUND: Reliable tools that allow precise and predictable control over gene expression are critical for the success of nearly all bioengineering applications. Translation initiation is the most regulated phase during protein biosynthesis, and is therefore a promising target for exerting control over gene expression. At the translational level, the copy number of a protein can be fine-tuned by altering the interaction between the translation initiation region of an mRNA and the ribosome...
March 14, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28314630/experiences-of-being-parents-of-young-adults-living-with-recessive-limb-girdle-muscular-dystrophy-from-a-salutogenic-perspective
#19
Anna Carin Aho, Sally Hultsjö, Katarina Hjelm
Recessive limb-girdle muscular dystrophies (LGMD2) involve progressive muscle weakness. Parental support is important for young adults living with LGMD2, but no study has been identified focusing on the parents' experiences. The salutogenic perspective concentrates on how daily life is comprehended, managed and found meaningful, i.e. the person's sense of coherence. The aim of this study was to describe, from a salutogenic perspective, experiences of being parents of young adults living with LGMD2. Nineteen participants were included...
February 3, 2017: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/28303385/after-effects-of-cerebellar-continuous-theta-burst-stimulation-on-reflexive-saccades-and-smooth-pursuit-in-humans
#20
Silvia Colnaghi, P Colagiorgio, S Ramat, E D'Angelo, G Koch, M Versino
The use of cerebellar repetitive transcranial magnetic stimulation has been attempted for perturbing reflexive and voluntary eye movements, but discrepancies are seen between the results of distinct studies possibly due to the different stimulation sites, intensities, and paradigms. We describe the after effects of 20 and 40 s continuous Theta Burst Stimulation (cTBS) as compared to sham stimulation, applied over the lateral cerebellar vermis and paravermis on Reflexive Saccades (RS) and Smooth Pursuit (SP) eye movements, recorded in the 30 min following stimulation...
March 16, 2017: Cerebellum
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