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Sexually transmitted infection

Derek T Dangerfield, Nina T Harawa, Laramie R Smith, William L Jeffries, Lourdes Baezconde-Garbanati, Ricky Bluthenthal
Black men who have sex with men and women (BMSMW) are at high risk for HIV and other sexually transmitted infections (STIs). Despite knowing that HIV/STI risk varies by sexual positioning practices, limited data have characterized the risk profiles of BSMW. This study utilized latent class analysis (LCA) to explore BMSMW's sexual risk profiles regarding condomless sexual positioning practices. Participants were BMSMW in intervention studies in Los Angeles, Chicago, and Philadelphia. LCA was used to characterize their sexual risk profiles...
March 14, 2018: Archives of Sexual Behavior
Nicole Stone, Cynthia Graham, Sydney Anstee, Katherine Brown, Katie Newby, Roger Ingham
Background: Condoms remain the main protection against sexually transmitted infections (STIs) when used correctly and consistently. Yet, there are many reported barriers to their use such as negative attitudes, reduced sexual pleasure, fit-and-feel problems and erection difficulties. The UK home-based intervention strategy (HIS-UK) is a behaviour change condom promotion intervention for use among young men (aged 16-25 years) designed to increase condom use by enhancing enjoyment of condom-protected intercourse...
2018: Pilot and Feasibility Studies
Guilherme Almeida Rosa da Silva, Heloisa Loureiro de Sá Neves Motta, Erik Friedrich Alex de Souza, Pedro Afonso Nogueira Moises Cardoso, José Henrique Pilotto, Walter Araujo Eyer-Silva, Luiz Cláudio Pereira Ribeiro, Mônica Soares Dos Santos, Marcelo Costa Velho Mendes de Azevedo, Jorge Francisco da Cunha Pinto, Rogerio Neves Motta, Fernando Raphael de Almeida Ferry
OBJECTIVES: The increase in HIV transmissibility in non-ulcerative sexually transmitted infection is already well-established. It is estimated that symptomatic carriers of N. gonorrhoeae and C. trachomatis have a relative risk of 4.8-fold and 3.6-fold, respectively, for the sexual acquisition of HIV. This type of evaluation for asymptomatic urethritis is necessary to reinforce strategies to combat HIV transmission. This study aims to assess the prevalence of patients with asymptomatic urethritis among men diagnosed with HIV-1 and determine the risk factors associated with this infection...
March 8, 2018: Revista do Instituto de Medicina Tropical de São Paulo
Laura H Bachmann, Bronwen Lichtenstein, Janet S St Lawrence, Margaret Murray, Gregory B Russell, Edward W Hook
OBJECTIVE: The aim of this study was to assess the general and sexual health of long-haul truck drivers in the United States. METHODS: Drivers were recruited from company sites and truck stops in North Carolina, Tennessee, and Mississippi. A sample of 266 drivers was assessed for lifestyle activities; body mass index and blood pressure were measured, and biologic samples were taken for cholesterol, diabetes, and sexually transmitted infection (STI)/HIV testing. RESULTS: The drivers in this study had higher levels of cholesterol and higher rates of smoking, obesity, and diabetes than the U...
March 13, 2018: Journal of Occupational and Environmental Medicine
Clarence S Yah, Geoffrey S Simate, Percy Hlangothi, Benesh M Somai
Objective: The human immunodeficiency virus (HIV) is among the utmost destructive viruses humankind has ever faced in almost four decades. It carries with it profound socioeconomic and public health implications. Unfortunately, there is, currently, no effective cure for HIV infections. This review discusses the various types of condoms, microbicides, and the potential use of nanoparticle-coated condoms as a means of diminishing the risk of HIV transmission and sexually transmitted infections (STIs) during sexual intercourse...
April 2018: Annals of African Medicine
Carmen H Logie, Candice L Lys, Nicole Schott, Lisa Dias, Makenzie R Zouboules, Kayley Mackay
Scant research has addressed health and well-being among lesbian, gay, bisexual, transgender, and queer (LGBTQ) persons in the Arctic. The Northwest Territories (NWT) has among Canada's highest rates of sexually transmitted infections (STIs). LGBTQ persons in NWT are at the nexus of LGBTQ and Arctic health disparities. Yet little is known of their sexual health needs. This qualitative study explored the sexual health needs of LGBTQ persons in the NWT. We conducted semi-structured, in-depth interviews with 51 participants, including 16 LGBTQ youth aged 15-24, 21 LGBTQ adults aged 25 and above, and 14 key informants who worked with LGBTQ persons...
March 13, 2018: Global Public Health
Xiaojing Zheng, Catherine M O'Connell, Wujuan Zhong, Uma M Nagarajan, Manoj Tripathy, De'Ashia Lee, Ali N Russell, Harold Wiesenfeld, Sharon Hillier, Toni Darville
Sexually transmitted infections with Chlamydia trachomatis and/or Neisseria gonorrhoeae and rates of pelvic inflammatory disease (PID) in women continue to rise, with reinfection being common because of poor adaptive immunity. Diagnosis remains imprecise, and pathogenesis data are derived primarily from monoinfection of mice with C. trachomatis or N. gonorrhoeae By comparing blood mRNA responses of women with C. trachomatis - and/or N. gonorrhoeae -induced PID and histologic endometritis with those from women with C...
March 12, 2018: Journal of Immunology: Official Journal of the American Association of Immunologists
Susanne Paukner, Astrid Gruss, Jørgen Skov Jensen
The pleuromutilin antibiotic lefamulin demonstrated in vitro activity against the most relevant bacterial pathogens causing sexually transmitted infections (STI) including Chlamydia trachomatis (MIC50/90 of 0.02/0.04 mg/L, n =15), susceptible and multidrug-resistant Mycoplasma genitalium (MIC range 0.002-0.063 mg/L, n =6) and susceptible and resistant Neisseria gonorrhoeae (MIC50/90 , 0.12/0.5 mg/L, n =25). The results suggest that lefamulin could be a promising first-line antibiotic for the treatment of STI, particularly in populations with high resistance rates to standard of care antibiotics...
March 12, 2018: Antimicrobial Agents and Chemotherapy
Patrick O'Byrne, Paul MacPherson, Lauren Orser
We trialed a nurse-led HIV postexposure prophylaxis (PEP) program in two sexually transmitted infection clinics in Ottawa, Canada. From September 5, 2013 to September 4, 2015, 112 persons sought PEP: 103 were male, of whom 84 were men who have sex with men (MSM). Seventy-two patients (59 MSM) initiated PEP; 11 were diagnosed with HIV: 6 diagnoses occurred during initial assessment (all MSM; 1 also shared injection equipment); 5 MSM were diagnosed with HIV within 1 year of seeking PEP. This level of positivity indicated that, when access is facilitated, individuals at high risk of HIV seek PEP...
February 17, 2018: Journal of the Association of Nurses in AIDS Care: JANAC
Andreas Brandt Gormsen, Jon Erik-Fraes Diernæs, Jørgen Skov Jensen, Uffe Koppelhus
This is a case report of lymphogranuloma venereum (LGV) manifesting as haemorrhagic proctocolitis in a homosexual HIV-positive male. The primary symptom was a rectal abscess, which was initially surgically treated and subsequently insufficiently treated with single-dose tablet azithromycin. The patient's symptoms were successfully treated after a 21-day doxycycline regime. LGV is a sexually transmitted infection with a rising incidence among persons with risk behaviour. This case report underlines the importance, that all positive rectal screenings for Chlamydia trachomatis should be routinely serotyped...
March 12, 2018: Ugeskrift for Laeger
Sally B Rose, Susan M Garrett, Susan R H Pullon
INTRODUCTION Sexual health guidelines recommend that partner notification and testing for reinfection are undertaken when individuals are diagnosed with bacterial sexually transmitted infections (STIs). AIM To understand factors influencing the effective delivery of partner notification and follow up after diagnosis of STIs in primary care, and to identify strategies that might facilitate these processes. METHODS A postal survey was sent to 216 primary care doctors and nurses working in 72 Wellington primary care settings...
June 2017: Journal of Primary Health Care
(no author information available yet)
No abstract text is available yet for this article.
April 2018: Sexually Transmitted Diseases
Charlotte A Gaydos
No abstract text is available yet for this article.
April 2018: Sexually Transmitted Diseases
Melissa A Habel, Kathryn A Brookmeyer, Robin Oliver-Veronesi, Michelle M Haffner
BACKGROUND: National-level data suggest that sexually transmitted infection (STI) testing rates among young adults are low. The purpose of this study was to evaluate the acceptability of an STI self-testing program at a university health center. Few evaluations on the acceptability of collegiate self-testing programs and their effect on testing uptake have been conducted. METHODS: To assess acceptability and uptake of self-testing (urine and self-collected vaginal swab), we conducted a brief self-administered survey of students accessing a large US-based university health center from January to December 2015...
April 2018: Sexually Transmitted Diseases
Agnese Comelli, Ilaria Izzo, Salvatore Casari, Angiola Spinetti, Alberto Bergamasco, Francesco Castelli
Since June 2016, an outbreak of hepatitis A has been reported in Europe. Here we report the HAV outbreak in Brescia (Northern Italy) from July 2016 to July 2017. We actively recorded all HAV cases defined by detection of HAV IgM antibodies in serum. Data on sexual behaviour, travel attitudes, concomitant sexually transmitted diseases (STDs), clinical presentation and laboratory results were collected. Forty-two confirmed cases were recorded: 25 (60%) were MSM and reported sexual contact at risk of STDs. Compared to 2015 and the first half of 2016, when only three hepatitis A cases were recorded, in the 12 months in question the number of cases rose 14-fold...
March 1, 2018: Le Infezioni in Medicina
Fatemeh Jahanbakhsh, Fahimeh Bagheri Amiri, Abbas Sedaghat, Noushin Fahimfar, Ehsan Mostafavi
BACKGROUND: This study investigated the prevalence for hepatitis A virus (HAV), hepatitis E virus (HEV), herpes simplex virus type 2 (HSV2) and syphilis among homeless in the city of Tehran. METHODS: In this cross-sectional study, 596 homeless were recruited in Tehran. A researcher-designed questionnaire was used to study demographic data. Using enzyme-linked immunoassay, and rapid plasma reagin (RPR) test, we evaluated the seroprevalence of HAV anti-body, HEV IgG, herpes, HSV2 IgG, and syphilis among sheltered homeless in Tehran...
July 8, 2017: International Journal of Health Policy and Management
Ryan E Wiegand, Gretchen Cooley, Brook Goodhew, Natalie Banniettis, Stephan Kohlhoff, Sarah Gwyn, Diana L Martin
Latent class modeling can be used to combine the results of multiple tests to compare the sensitivity and specificity of those tests in the absence of a gold standard. Seroepidemiology for chlamydia infection may be useful for determining the cumulative risk of infection within a population. Initial studies using the Chlamydia trachomatis immunodominant antigen Pgp3 have shown utility for seroepidemiology of sexually transmitted chlamydia and the eye disease trachoma. We present our latent class modeling results for comparison of antibody data obtained from three different Pgp3-based platforms - multiplex bead array, ELISA, and lateral flow assay...
March 9, 2018: Scientific Reports
William H Palmer, Finny S Varghese, Ronald P van Rij
The power and ease of Drosophila genetics and the medical relevance of mosquito-transmitted viruses have made dipterans important model organisms in antiviral immunology. Studies of virus-host interactions at the molecular and population levels have illuminated determinants of resistance to virus infection. Here, we review the sources and nature of variation in antiviral immunity and virus susceptibility in model dipteran insects, specifically the fruit fly Drosophila melanogaster and vector mosquitoes of the genera Aedes and Culex ...
March 9, 2018: Viruses
Hersha Patel, Esther L Moss, Susan M Sherman
BACKGROUND: Primary HPV cervical screening is due to be implemented in England within the next 2years however, the acceptability of HPV testing as the primary screening test is unclear. This study explores women's awareness and attitudes towards HPV testing/screening. METHODS: Qualitative interviews (semi-structured and focus group) were conducted with forty-six women (aged 25-65years) from community and secondary care settings. Data was analysed using the inductive-framework method...
March 9, 2018: Psycho-oncology
Victoria Hall, William L Walker, Nicole P Lindsey, Jennifer A Lehman, Jonathan Kolsin, Kimberly Landry, Ingrid B Rabe, Susan L Hills, Marc Fischer, J Erin Staples, Carolyn V Gould, Stacey W Martin
Zika virus is a flavivirus primarily transmitted to humans by Aedes aegypti mosquitoes (1). Zika virus infections also have been documented through intrauterine transmission resulting in congenital infection; intrapartum transmission from a viremic mother to her newborn; sexual transmission; blood transfusion; and laboratory exposure (1-3). Most Zika virus infections are asymptomatic or result in mild clinical illness, characterized by acute onset of fever, maculopapular rash, arthralgia, or nonpurulent conjunctivitis; Guillain-Barré syndrome, meningoencephalitis, and severe thrombocytopenia rarely have been associated with Zika virus infection (1)...
March 9, 2018: MMWR. Morbidity and Mortality Weekly Report
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