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Sexuality and Aging

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https://www.readbyqxmd.com/read/28938423/igfbp4-is-required-for-adipogenesis-and-influences-the-distribution-of-adipose-depots
#1
David E Maridas, Victoria E DeMambro, Phuong T Le, Subburaman Mohan, Clifford J Rosen
Insulin-like Growth Factor I (IGF-I) induces adipogenesis in vitro. IGF Binding Protein 4 (IGFBP4) is highly expressed in adipocytes and osteoblasts and is inhibitory of IGFs in vitro. We previously reported that Igfbp4 null mice (Igfbp4-/-) had decreased fat proportions at 8 and 16 weeks of age. However, the mechanism leading to the reduced adiposity remains unknown. The purpose of this study was to elucidate how IGFBP4 mediates adipose tissue development in vivo. Our results showed that inguinal (iWAT) and gonadal (gWAT) white adipose tissues from Igfbp4-/- mice had decreased weights and Pparγ expression...
July 27, 2017: Endocrinology
https://www.readbyqxmd.com/read/28938422/prepubertal-development-of-gonadotropin-releasing-hormone-gnrh-neuron-activity-is-altered-by-sex-age-and-prenatal-androgen-exposure
#2
Eden A Dulka, Suzanne M Moenter
Gonadotropin-releasing hormone (GnRH) neurons regulate reproduction though pulsatile hormone release. Disruption of GnRH release as measured via LH pulses occurs in polycystic ovary syndrome (PCOS), and in young hyperandrogenemic girls. In adult prenatally androgenized (PNA) mice, which exhibit many aspects of PCOS, increased LH is associated with increased GnRH neuron action potential firing. How GnRH neuron activity develops over the prepubertal period and whether or not this is altered by sex or prenatal androgen treatment are unknown...
September 15, 2017: Endocrinology
https://www.readbyqxmd.com/read/28938228/sex-determination-from-chest-measurements-in-a-sample-of-egyptian-adults-using-multislice-computed-tomography
#3
Ragaa T Darwish, Manal H Abdel-Aziz, Abdel-Aziz M El Nekiedy, Zahraa K Sobh
BACKGROUND: In forensic sciences to determine one's sex is quite important during the identity defining stage. The reliability of sex determination depends on the completeness of the remains and the degree of sexual dimorphism inherent in the population. Computed Tomography is the imaging modality of choice for two- and three-dimensional documentation and analysis of many autopsy findings. OBJECTIVE: The aim of the present work was to assess the reliability of Three-dimensional Multislice Computed Tomography (3D MSCT) to determine sexual dimorphism from certain chest measurements; sternum and fourth rib using the 3D MSCT and to develop equations for sex determination from these bones among adult Egyptians sample...
September 11, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28937851/hpv-vaccine-acceptability-in-high-risk-greek-men
#4
Lea Hoefer, Savas Tsikis, George Bethimoutis, Electra Nicolaidou, Vassilios Paparizos, Christina Antoniou, Antonios Kanelleas, Leonidas Chardalias, Georgios-Emmanouil Stavropoulos, John Schneider, Angella Charnot-Katsikas
BACKGROUND: HPV is associated with malignancy in men, yet there is a lack of data on HPV knowledge, vaccine acceptability, and factors affecting vaccine acceptability in Greek men. This study aims to identify determinants of knowledge and willingness to vaccinate against HPV among high-risk Greek men. METHODS: Men (n = 298) between the ages of 18 and 55 were enrolled from the STI and HIV clinics at "Andreas Syggros" Hospital in Athens, Greece from July-October 2015...
September 22, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28935660/childhood-adversities-and-post-traumatic-stress-disorder-evidence-for-stress-sensitisation-in-the-world-mental-health-surveys
#5
Katie A McLaughlin, Karestan C Koenen, Evelyn J Bromet, Elie G Karam, Howard Liu, Maria Petukhova, Ayelet Meron Ruscio, Nancy A Sampson, Dan J Stein, Sergio Aguilar-Gaxiola, Jordi Alonso, Guilherme Borges, Koen Demyttenaere, Rumyana V Dinolova, Finola Ferry, Silvia Florescu, Giovanni de Girolamo, Oye Gureje, Norito Kawakami, Sing Lee, Fernando Navarro-Mateu, Marina Piazza, Beth-Ellen Pennell, José Posada-Villa, Margreet Ten Have, Maria Carmen Viana, Ronald C Kessler
BackgroundAlthough childhood adversities are known to predict increased risk of post-traumatic stress disorder (PTSD) after traumatic experiences, it is unclear whether this association varies by childhood adversity or traumatic experience types or by age.AimsTo examine variation in associations of childhood adversities with PTSD according to childhood adversity types, traumatic experience types and life-course stage.MethodEpidemiological data were analysed from the World Mental Health Surveys (n = 27 017)...
September 21, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28935384/disparities-in-body-mass-index-trajectories-from-adolescence-to-early-adulthood-for-sexual-minority-women
#6
Sarah M Wood, Whitney Schott, Michael P Marshal, Aletha Y Akers
PURPOSE: We aimed to estimate group-based trajectories of body mass index (BMI) in a longitudinal cohort of young women and determine the association between sexual identity and BMI trajectory group, adjusting for obesity risk factors. METHODS: We analyzed data from females in waves I-IV of the National Longitudinal Study of Adolescent to Adult Health. Sexual identity was categorized as heterosexual, mostly heterosexual, bisexual, or lesbian (homosexual/mostly homosexual)...
September 18, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28935238/biphasic-aspect-of-sexually-dimorphic-ontogenetic-trajectory-of-gyrification-in-the-ferret-cerebral-cortex
#7
K Sawada, I Aoki
The present study characterized quantitatively sexual dimorphic development of gyrification by MRI-based morphometry. High spatial-resolution 3D MR images (using RARE sequence with short TR and minimum TE setting) were acquired from fixed brain of male and female ferrets at postnatal days (PDs) 4 to 90 using 7-tesla preclinical MRI system. The gyrification index was evaluated either throughout the cerebral cortex (global GI) or in representative primary sulci (sulcal GI). The global GI increased linearly from PD 4, and reached a peak at PD 42, marking 1...
September 18, 2017: Neuroscience
https://www.readbyqxmd.com/read/28934729/the-effect-of-perceived-stress-on-epstein-barr-virus-antibody-titers-in-appalachian-ohio-women
#8
Melissa J Brook, Lisa M Christian, Erinn M Hade, Mack T Ruffin
OBJECTIVE: The Appalachian population suffers a disparate burden of chronic stress leading to high perceived stress. The study aim was to determine the association between perceived stress and Epstein-Barr virus (EBV) antibody titers, along with the impact of perceived social support, Appalachian self-identify, and health behaviors. METHODS: Serum EBV VCA-IgG antibody titer levels from 169 female Appalachian residents (aged 18-26 years) were examined. Perceived stress, perceived social support, Appalachian self-identity, and health behaviors were assessed via self-administered questionnaires...
September 22, 2017: Neuroimmunomodulation
https://www.readbyqxmd.com/read/28934330/an-analysis-of-beak-shape-variation-in-two-ages-of-domestic-turkeys-meleagris-gallopavo-using-landmark-based-geometric-morphometrics
#9
Hillary A Dalton, Benjamin J Wood, Tina M Widowski, Michele T Guerin, Stephanie Torrey
The objective of this study was to assess beak shape variation in domestic turkeys (Meleagris gallopavo) and determine the effects of age, sex, and beak size on beak shape variation using geometric morphometrics. Dorsal and right lateral images were taken of 2442 turkeys at 6 and 18.5 weeks of age. Landmarks were digitized in tpsDig in three analyses of the dorsal upper mandible, lateral upper mandible, and lateral lower mandible shape of each turkey at both ages. The coordinate data were then subjected to a principal components analysis (PCA), multivariate regression, and a canonical variates analysis (CVA) with a Procrustes ANOVA in MorphoJ...
2017: PloS One
https://www.readbyqxmd.com/read/28934174/attitudes-beliefs-and-predictors-of-male-circumcision-promotion-among-medical-university-students-in-a-traditionally-non-circumcising-region
#10
Maria Ganczak, Marcin Korzeń, Maciej Olszewski
Objective: To evaluate the beliefs of medical university students regarding male circumcision (MC), as well as attitudes and the predictors of its promotion in the case of adults at risk of HIV. Methods: A cross-sectional survey was conducted between 2013-2016 at the Medical University in Szczecin, Poland, among final year Polish/foreign students from Northern Europe, using a standardized questionnaire. Results: There were 539 participants, median age 25 years, 40.8% males, and 66.8% were Polish nationals. The MC rate was 16...
September 21, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28933951/a-developmentally-relevant-approach-to-classifying-nonconsensual-sexual-experiences-in-the-study-of-women-s-sexual-well-being
#11
Chelsea D Kilimnik, Cindy M Meston
In this article we propose a sexual developmental approach to classifying the onset of nonconsensual sexual experiences (NSEs) that differs from the traditional age cutoff approach. Online measures of sexual self-schemas, sexual response, and sexual functioning were administered to 797 women with and without NSE histories. Women were grouped based on when their NSEs first occurred in reference to their age of menarche and age of their first consensual sexual experience (i.e., premenarche onset, postmenarche preconsensual onset, postconsensual onset, and no NSEs)...
September 21, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/28933870/the-role-of-young-adult-social-bonds-substance-problems-and-sexual-risk-in-pathways-between-adolescent-substance-use-and-midlife-risky-sexual-behavior-among-urban-african-americans
#12
Katarzyna A Zebrak, Kerry M Green
African Americans are disproportionately affected by HIV/AIDS and other sexually transmitted infections relative to other racial groups. Although substance use has been linked to risky sexual behavior, the understanding of how these associations develop over the life course remains limited, particularly the role of social bonds. This study uses structural equation modeling to examine pathways from adolescent substance use to young adult sexual risk, substance problems, and social bonds and then to midlife risky sexual behavior among African American men and women, controlling for childhood confounders...
September 21, 2017: Psychology of Addictive Behaviors: Journal of the Society of Psychologists in Addictive Behaviors
https://www.readbyqxmd.com/read/28933037/effects-of-strain-sex-and-season-on-body-weight-development-of-cane-rat-thryonomys-swinderianus-in-the-humid-tropics
#13
Oluwatosin M A Jesuyon
The effects of strain (G), sex (H), and season (S) on live weight development of cane rats (Thryonomys swinderianus) reared in captive system were investigated during the dry (35.95 °C) and wet seasons (25.81 °C) from February to August of a tropical environment. The field experiment took place at the University of Ibadan. Seventy-nine cane rats spreading among three genotypes (Bamidele, FRIN, and Lawole) of different age and body weight groups were randomly distributed into cages using randomized complete block design in factorial...
September 20, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28931963/-when-you-re-a-baby-you-don-t-have-puberty-understanding-of-puberty-and-human-reproduction-in-late-childhood-and-early-adolescence
#14
Lisa B Hurwitz, Alexis R Lauricella, Brianna Hightower, Iris Sroka, Teresa K Woodruff, Ellen Wartella
Basic knowledge of human reproduction can help youth prepare for puberty and make later classes focused on advanced reproductive health topics manageable. With the intention of potentially informing the creation of learning materials, we conducted a needs assessment among children ages 7 to 12 in our suburban Chicago community to ascertain their current understanding of, and beliefs and misconceptions about, human reproduction, and to determine their needs for additional reproductive health education. We held qualitative focus group interviews with local children...
August 2017: Journal of Early Adolescence
https://www.readbyqxmd.com/read/28931221/modeling-of-us-human-papillomavirus-hpv-seroprevalence-by-age-and-sexual-behavior-indicates-an-increasing-trend-of-hpv-infection-following-the-sexual-revolution
#15
Marc D Ryser, Anne Rositch, Patti E Gravitt
Background: The United States has experienced an increase in the incidence of human papillomavirus (HPV)-related cancers that are not screen-detectable. It has been hypothesized, but not directly demonstrated, that this is due to increasing HPV prevalence in the unvaccinated population. Methods: Female self-reported numbers of lifetime sex partners and HPV serology from the National Health and Nutrition Examination Survey (NHANES) were used to develop mathematical models of sexual partner acquisition and antibody dynamics...
September 1, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28931217/prevalence-of-human-papillomavirus-among-females-after-vaccine-introduction-national-health-and-nutrition-examination-survey-united-states-2003-2014
#16
Sara E Oliver, Elizabeth R Unger, Rayleen Lewis, Darius McDaniel, Julia W Gargano, Martin Steinau, Lauri E Markowitz
Background: Human papillomavirus (HPV) vaccine was recommended in 2006 for routine vaccination of US females aged 11-12 years. Most vaccine used through 2014 was quadrivalent vaccine (4vHPV), which prevents HPV-6, -11, -16, and -18 infection. To evaluate vaccine impact, we measured HPV prevalence in the National Health and Nutrition Examination Survey (NHANES). Methods: We analyzed HPV DNA types detected in self-collected cervicovaginal specimens and demographic, sexual behavior, and self-reported vaccination data from females 14-34 years old...
September 1, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28931062/factors-associated-with-hepatitis-c-prevalence-differ-by-the-stage-of-liver-fibrosis-a-cross-sectional-study-in-the-general-population-in-poland-2012-2016
#17
Magdalena Rosińska, Natalia Parda, Agnieszka Kołakowska, Paulina Godzik, Karolina Zakrzewska, Kazimierz Madaliński, Andrzej Zieliński, Anna Boguradzka, Rafał Gierczyński, Małgorzata Stępień
BACKGROUND & AIMS: There is a considerable burden of hepatitis C in Europe related to the lack of prompt diagnosis. We aimed to estimate the prevalence and related risk factors of HCV infections by the stages of liver fibrosis, using non-invasive methods, to understand testing needs in Poland. METHODS: A cross-sectional study was conducted in 2012-2016 adopting a stratified random sampling of primary health care units followed by systematic sampling of patients within each unit...
2017: PloS One
https://www.readbyqxmd.com/read/28930668/aspects-of-sexual-precocity-and-morphometry-of-uterus-placenta-and-embryos-fetuses-in-piau-breed-and-commercial-line-gilts
#18
José Carlos Montes, Jurandy Mauro Penitente-Filho, Simone Eliza Facioni Guimarães, Paulo Sávio Lopes, Breno Soares Camilo, Hugo Hideki Shiomi, Daniel Araújo Lima, Rogério Oliveira Pinho, Jhonata Vieira Tavares do Nascimento Pereira, Denise Silva Okano, Karine Assis Costa, José Domingos Guimarães
In view of the importance of the genetic material of local breeds in the swine industry and the lack of information about reproductive performance of Piau females, two experiments were conducted to evaluate puberty and sexual maturity as well as the morphometry of embryos/fetuses, placenta and uterus during the first 90 days of gestation in Piau breed and Commercial line gilts. In experiment I, 37 Piau and 25 commercial line gilts were used. From the 120 days of age, detection of estrus was performed using mature boars from the first to third estrus of each gilt...
September 12, 2017: Theriogenology
https://www.readbyqxmd.com/read/28930068/risk-for-alcohol-exposed-pregnancies-among-women-at-drinking-venues-in-cape-town-south-africa
#19
Melissa H Watt, Brandon A Knettel, Karmel W Choi, Elizabeth T Knippler, Philip A May, Soraya Seedat
OBJECTIVE: South Africa's Western Cape Province has one of the highest rates of fetal alcohol spectrum disorder globally. Alcohol-serving venues are likely important sites to identify women at high risk of having a child with fetal alcohol spectrum disorder. The goal of this study was to examine the risk for alcohol-exposed pregnancies among women who drink in alcohol-serving venues. METHOD: Cross-sectional surveys were conducted with 200 women of reproductive age at seven drinking venues in a single Cape Town community...
September 2017: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/28929998/calcaneal-tendon-collagen-fiber-morphometry-and-aging
#20
Daniel Hadraba, Jiri Janacek, Eva Filova, Frantisek Lopot, Rik Paesen, Ondrej Fanta, Anneliese Jarman, Alois Necas, Marcel Ameloot, Karel Jelen
Fibrillar collagen in tendons and its natural development in rabbits are discussed in this paper. Achilles tendons from newborn (~7 days) to elderly (~38 months) rabbits were monitored in intact (n tendons=24) and microtome sectioned (n tendons=11) states with label-free second harmonic generation microscopy. After sectioning, the collagen fiber pattern was irregular for the younger animals and remained oriented parallel to the load axis of the tendon for the older animals. In contrast, the collagen fiber pattern in the intact samples followed the load axis for all the age groups...
September 20, 2017: Microscopy and Microanalysis
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