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https://www.readbyqxmd.com/read/28431236/unicystic-ameloblastoma-revisited-comparison-of-massachusetts-general-hospital-outcomes-with-original-robinson-and-martinez-report
#1
Anne-Frédérique Chouinard, Zachary S Peacock, William C Faquin, Leonard B Kaban
PURPOSE: Robinson and Martinez established unicystic ameloblastoma (UA) as a distinct pathologic entity in 1977. By use of their original description, the aim of this study was to compare the clinical presentation and outcomes of UA treated at Massachusetts General Hospital (MGH) with outcomes reported in the original article. PATIENTS AND METHODS: This was a retrospective cohort study of MGH patients treated for UA during a 15-year period. Patients were included if they had a confirmed clinical and histologic diagnosis of UA...
March 27, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28390135/comparative-histological-and-immunohistochemical-study-of-ameloblastomas-and-ameloblastic-carcinomas
#2
M Martínez-Martínez, A Mosqueda-Taylor, R Carlos-Bregni, F Ramoa-Pires, W Delgado-Azanero, R Neves-Silva, B Aldape-Barrios, O Paes-de Almeida
BACKGROUND: This study aimed to compare the histological and immunohistochemical characteristics of ameloblastomas (AM) and ameloblastic carcinomas (AC). MATERIAL AND METHODS: Fifteen cases of AM and 9 AC were submitted to hematoxilin and eosin (H&E) and immunohistochemical analysis with the following antibodies: cytokeratins 5,7,8,14 and 19, Ki-67, p53, p63 and the cellular adhesion molecules CD138 (Syndecan-1), E-cadherin and β-catenin. The mean score of the expression of Ki-67 and p53 labelling index (LIs) were compared between the groups using the t test...
April 8, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/28384994/a-rare-case-of-adenomatoid-odontogenic-tumour-with-unicystic-ameloblastoma
#3
Vidya Karnam Sathyanarayana, Huldah Srigiri, Mounija Cheemalavagupalli, Sairam Vankadara, Geetha Malika
No abstract text is available yet for this article.
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28340422/the-clinicopathologic-relevance-of-reck-gene-polymorphisms-in-ameloblastoma
#4
Xudong Zhang, Jie Wang, Huijuan Liu, Yanning Zhang, Fusheng Dong
OBJECTIVE: To investigate the relationship between RECK gene polymorphisms and the clinicopathologic features of ameloblastoma. DESIGN: Normal gingival mucosa specimens were obtained from 10 healthy volunteers. Ameloblastomas were surgically removed from 30 patients and part of the tumor specimens were used to detect RECK gene polymorphisms by using PCR-single-strand conformation polymorphism (PCR-SSCP) and DNA sequencing analysis. Expression of RECK and MMP-9 protein was measured using western blot...
March 16, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28316917/a-comparative-study-of-syndecan-1-expression-in-different-odontogenic-tumors
#5
Shahroo Etemad-Moghadam, Mojgan Alaeddini
BACKGROUND: Expression of various cellular/molecular factors change during the course of tumor formation from odontogenic tissues of the tooth germ. Evaluation of these factors can help provide a better perception of the tumorigenesis and biologic behavior of odontogenic tumors (OTs). Syndecan-1 is a heparan sulfate proteoglycan which has not been extensively investigated in these lesions. The objective of the present study was to assess the immunohistochemical expression of CD138 in adenomatoid odontogenic tumor (AOT), ameloblastic fibroma (AF) and odontogenic myxoma (OM) and to compare it with ameloblastoma and keratocystic odontogenic tumor (KCOT)...
January 2017: Journal of Oral Biology and Craniofacial Research
https://www.readbyqxmd.com/read/28292394/intramural-unicystic-ameloblastoma
#6
Manas Bajpai, Nilesh Pardhe
No abstract text is available yet for this article.
February 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28292369/premolar-cystic-ameloblastoma-in-a-child
#7
Sanyog Pathak, Wanjari Ghate Sonalika, Vanishree Hs, Anand S Tegginammani
Mandibular swellings may occur as a result of many benign lesions of odontogenic or non-odontogenic origin. Ameloblastomas are benign tumours of odontogenic origin, whose importance lies in its potential to grow into enormous size with resulting bone deformity, it is a slow-growing, persistent, and locally aggressive neoplasm. The unicystic ameloblastoma (UA) represents an ameloblastoma variant, presenting as a cyst clinically and radiographically, but showing typical ameloblastomatous epithelium lining histologically...
January 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28290306/a-historical-case-of-an-ameloblastoma-from-southern-italy
#8
J Cilli, R D'Anastasio
Jawbones are susceptible to various tumours, some of which originate from dental structures. Here we describe a case of a tumour in a mandible of an old man that was discovered during an archaeological excavation in southern Italy (Torrecuso; 17th-19th centuries). The right mandibular branch presents an extended, multilocular lesion. X-ray analysis shows erosion of the cortical bone layers and the thin trabeculae that circumscribe the lobular areas. Macroscopic and radiological aspects of the mandibular lesion are consistent with an ameloblastoma...
March 2017: International Journal of Paleopathology
https://www.readbyqxmd.com/read/28286387/immunohistochemistry-of-five-molecular-markers-for-typing-and-management-of-ameloblastomas-a-retrospective-analysis-of-40-cases
#9
Thasvir Singh, Arun Chandu, John Clement, Christopher Angel
PURPOSE: The aims of this study are to elucidate if molecular markers can be used to differentiate between the two main types of ameloblastoma (unicystic and solid/multicystic), and to determine whether a biologically 'less-aggressive' subtype exists. METHODS: A retrospective analysis of 33 solid/multicystic ameloblastomas and six unicystic ameloblastomas was completed using immunohistochemistry for five molecular markers: P16, P53, MMP-9, Survivin, and Ki-67. Tumors were graded as either negative or positive (mild, moderate, strong), and the results were related to both ameloblastoma subtypes and outcomes following treatment...
March 2017: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/28284724/langerhans-cells-in-granular-cell-ameloblastoma
#10
Yu-Hsueh Wu, Julia Yu-Fong Chang, Yi-Ping Wang, Chun-Pin Chiang
No abstract text is available yet for this article.
March 8, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28274671/second-opinion-oral-pathology-referrals-in-new-zealand
#11
B Seo, H M Hussaini, A M Rich
Referral for a second opinion is an important aspect of pathology practice, which reduces the rate of diagnostic error and ensures consistency with diagnoses. The Oral Pathology Centre (OPC) is the only specialist oral diagnostic centre in New Zealand. OPC provides diagnostic services to dentists and dental specialists throughout New Zealand and acts as a referral centre for second opinions for oral pathology specimens that have been sent to anatomical pathologists. The aim of this study was to review second opinion referral cases sent to the OPC over a 15-year period and to assess the levels of concordance between the original and final diagnoses...
April 2017: Pathology
https://www.readbyqxmd.com/read/28274070/a-rare-case-report-of-spindle-cell-ameloblastic-carcinoma-involving-the-mandible
#12
Mohammad Asif Kiresur, Arunodaya Kunche, Anuradha Ananthaneni, Bhavana S Bagalad, Puneeth Horatti Kuberappa
Ameloblastic Carcinoma (AC) is uncommon malignant epithelial odontogenic tumour of jaw, with characteristic histologic features and behavior. Clinically, it has aggressive, infiltrative growth pattern with a distinct predilection for mandible. It exhibits histologic features of ameloblastoma and gets dedifferentiated overtime to culminate in carcinoma. Majority of the cases arise denovo (primary) and only few cases arise from a pre-existing ameloblastoma (secondary). Spindle-cell differentiation in ameloblastic carcinoma is rare; Salter described it as a separate entity "low-grade spindle cell ameloblastic carcinoma...
January 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28274056/analysis-of-prevalence-and-clinical-features-of-ameloblastoma-and-its-histopathological-subtypes-in-southeast-myanmar-and-lower-northern-thailand-populations-a-13-year-retrospective-study
#13
Chaidan Intapa
INTRODUCTION: Prevalence of ameloblastomas has been established worldwide but collective data of ameloblastoma in Southeast Asian countries has not been well analyzed. AIM: Aim of this study was to report analysis and comparison of the prevalence and demographic data of clinical features of ameloblastoma and its histopathological variants in Southeast Myanmar and lower Northern Thailand populations. MATERIALS AND METHODS: A retrospective study on ameloblastoma was performed based on the availability of oral biopsy specimens in Faculty of Dentistry, Naresuan University, Phitsanulok, Thailand, between January 2002 and August 2015...
January 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28272008/an-expansile-well-defined-radiolucency-in-anterior-mandible-case-presentation-with-treatment-approach-and-literature-update
#14
Shelly Arora, Aadithya B Urs, Zainab Choudhary
A 15-year-old Indian male patient presented with a history of pain and swelling in left mandible. Imaging studies revealed a well-defined unilocular radiolucency in the body of the mandible. Patient also gave the past history of the surgery of the jaws, which was histopathologically diagnosed as dentigerous cyst. Following this patient underwent incisional biopsy and later excisional biopsy. The histopathologic diagnosis for incisional biopsy was unicystic ameloblastoma but final diagnosis was dentinogenic ghost cell tumor for the excised tissue...
January 2017: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/28248452/dna-methylation-pattern-of-apoptosis-related-genes-in-ameloblastoma
#15
Sfs Costa, N B Pereira, Kma Pereira, K Campos, W H de Castro, M G Diniz, C C Gomes, R S Gomez
OBJECTIVES: DNA methylation is an important mechanism of gene control expression, and it has been poorly addressed in odontogenic tumours. On this basis, we aimed to assess the methylation pattern of 22 apoptosis-related genes in solid ameloblastomas. MATERIALS AND METHODS: Ameloblastoma fresh samples (n = 10) and dental follicles (n = 8) were included in the study. The percentage fraction of methylated and unmethylated DNA promoter of 22 apoptosis-related genes was determined using enzymatic restriction digestion and quantitative real-time PCR (qPCR) array...
March 1, 2017: Oral Diseases
https://www.readbyqxmd.com/read/28238093/role-of-hif-1%C3%AE-and-caspase-3-in-cystogenesis-of-odontogenic-cysts-and-tumors
#16
Natacha M M da Costa, Adriane S de Siqueira, André L R Ribeiro, Maria S da Silva Kataoka, Ruy G Jaeger, Sérgio M de Alves-Júnior, Andrew M Smith, João de Jesus Viana Pinheiro
OBJECTIVES: Odontogenic cysts and tumors are the most relevant lesions that affect the gnathic bones. These lesions have in common the formation of cystic areas and this common feature may suggest involvement of similar mechanisms. The hypoxia inducible factor 1 alpha (HIF-1α), a responsive protein to hypoxia and caspase-3, an irreversible apoptosis marker, may contribute to cyst formation. Thus, this study aimed to investigate the immunoexpression of these proteins in odontogenic cysts and tumors...
February 25, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28230919/maxillary-ameloblastoma-factors-associated-with-risk-of-recurrence
#17
Rong Yang, Zheqi Liu, Canbang Peng, Wei Cao, Tong Ji
BACKGROUND: Maxillary ameloblastomas are rare and associated with an aggressive course because of the anatomic composition of the maxilla and adjacent structures. The risk factors associated with recurrence were analyzed in this retrospective study. METHODS: Cases of maxillary ameloblastoma reported in a tertiary hospital from 2005 to 2015 were analyzed to identify clinicopathological and radiological factors associated with recurrence using univariate and multivariate Cox regression analyses...
February 23, 2017: Head & Neck
https://www.readbyqxmd.com/read/28222389/correlation-between-ploidy-status-using-flow-cytometry-and-nucleolar-organizer-regions-in-benign-and-malignant-epithelial-odontogenic-tumors
#18
Sarah Ahmed Mohamed Mahmoud, Dalia Hussein El-Rouby, Safa Fathy Abd El-Ghani, Omnia Mohamed Badawy
OBJECTIVE: Differentiation between the aggressive benign odontogenic tumors and their malignant counterparts is controversial and difficult. While flow cytometry (FCM) allowed DNA analysis in neoplasia, argyrophilic organizer regions (AgNORs) number and/or size in a nucleus are correlated with the ribosomal gene activity and therefore with cellular proliferation. The aim of this research was to study the diagnostic accuracy of FCM and AgNORs staining in differentiating between benign and malignant epithelial odontogenic tumors and to correlate between these two interventions...
February 14, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28212886/primary-ameloblastoma-of-the-temporal-bone
#19
Andro Košec, Jakov Ajduk, Mihael Ries, Robert Trotić
Ameloblastoma is a locally aggressive tumor derived from odontogenic epithelium. Although benign, its clinical behavior can often exhibit malignant characteristics. It is marked by slow and persistent growth with infiltration of adjacent tissues. Almost 70% occur in the mandible in patients older than 30 years. Recurrence of ameloblastoma from inadequate treatment is frequent. Because of its slow growth, recurrences can present decades after primary surgery. A primary ameloblastoma in an area outside the mandibular, maxillary, and infratemporal fossa regions has not been described in detail to date, with only 1 possible case mentioned in the literature...
January 24, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28191811/metastatic-ameloblastoma-to-brain-a-rare-entity
#20
Arif Sarmast, Khursheed Nayil-M, Rumana Makhdoomi, Azhar Butto, Altaf Ramzan
Ameloblastoma is a rare odontogenic tumor of the jaw. It is a benign neoplasm but local recurrence is common. Metastasis from this tumor is all the more rare. The commonest site for metastasis is lung. Brain is a very uncommon site of involvement. Overall prognosis is good. We hereby discuss ameloblastoma of lower jaw in a young adult which had metastasized to brain. Patient was operated for the metastatic lesion of brain and is doing well on follow-up.
September 2016: Gulf Journal of Oncology
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