keyword
MENU ▼
Read by QxMD icon Read
search

Ameloblastoma

keyword
https://www.readbyqxmd.com/read/28797453/oncogenic-signalling-pathways-in-benign-odontogenic-cysts-and-tumours
#1
REVIEW
Marina Gonçalves Diniz, Carolina Cavalieri Gomes, Sílvia Ferreira de Sousa, Guilherme Machado Xavier, Ricardo Santiago Gomez
The first step towards the prevention of cancer is to develop an in-depth understanding of tumourigenesis and the molecular basis of malignant transformation. What drives tumour initiation? Why do most benign tumours fail to metastasize? Oncogenic mutations, previously considered to be the hallmark drivers of cancers, are reported in benign cysts and tumours, including those that have an odontogenic origin. Despite the presence of such alterations, the vast majority of odontogenic lesions are benign and never progress to the stage of malignant transformation...
September 2017: Oral Oncology
https://www.readbyqxmd.com/read/28795546/-unicystic-ameloblastoma-presenting-in-delleman-s-syndrome
#2
Y Gilon, F Thonnart
Ameloblastoma is an odontogenic tumour that represents 1 % of oral tumours but 10 % of odontogenic tumours. Ameloblastoma is characterized by low and noiseless growth, that explains a lot of advanced forms. The tumour is known as benign with local malignity due to its locally invasive behaviour and its recurrence. The treatment choice remains complicated because of recurring nature and large resection in vital anatomical areas. The therapeutic approach will be based on size, anatomical localisation, histologic variants and anatomical complications...
July 2017: Revue Médicale de Liège
https://www.readbyqxmd.com/read/28764951/reconstruction-of-the-bony-chin-using-sagittal-split-osteotomies-of-the-remaining-mandible-a-new-technique-for-a-special-indication-case-report
#3
Berthold H Hell
There are several indications for resecting the bony chin, such as squamous cell carcinoma, sarcoma, or benign tumors of the jaw such as ameloblastoma. Several techniques for reconstruction of the bony chin, such as the use of metal plates and also revascularized free bone grafts of the iliac crest, fibula, or scapula, are common. In the case of poor vascular supply, however, alternative techniques may be necessary. In this report, a new technique is described using pedicled bone flaps from both sagittally split mandibular stumps following chin resection...
June 16, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28764292/focal-adhesion-kinase-expression-in-ameloblastoma-a-preliminary-observational-study
#4
Snehal Patil, Gargi Sachin Sarode, Sachin C Sarode, Rahul Anand, Shankargouda Patil
INTRODUCTION: Focal Adhesion Kinase (FAK) is a membrane-associated molecule, which plays a major role in tumourigenesis by promoting cell survival, proliferation, migration, and invasion. Hence, FAK is a well known molecule that has been targeted therapeutically for the treatment of various malignancies. Ameloblastoma (AB) is a locally invasive, destructive and recurrent benign odontogenic lesion. Based on these properties, we have hypothesized that odontogenic epithelium of AB could show increased expression of FAK...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28761644/an-extensive-swelling-in-the-anterior-mandible-a-case-report
#5
Nikhil M Kurien, L K Surej Kumar, P B Uma, V Vivek, Anna P Joseph
INTRODUCTION: Glandular odontogenic cyst is a rare developmental odontogenic cyst, which often pose a challenge to diagnose it clinically. PRESENTATION OF A CASE: A 32 year old female patient was referred to the oral and maxillofacial surgery department with a chief complaint of a painless swelling in the anterior mandible, extending from mandibular left premolar to right first molar region, with fluctuancy and egg shell crackling at right premolar region. The associated teeth were firm...
September 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28749026/maxillary-unicystic-ameloblastoma-in-a-6-week-old-filly-evaluated-with-computed-tomography
#6
H L Smith, A J Rosenblatt, W W Suen, H Owen, B J Ahern
CASE REPORT: A 6-week-old Thoroughbred filly was presented for evaluation of an expansile mass overlying the right nasal passage and causing respiratory stertor. On skull radiographs, there was a loculated, soft tissue-opaque mass identified dorsal to the right upper premolars and effacing the right nasal cavity. Computed tomography (CT) revealed a locally extensive mass with relatively benign characteristics located centrally on the tooth root apices of the deciduous second premolar (506)...
August 2017: Australian Veterinary Journal
https://www.readbyqxmd.com/read/28749023/in-this-issue-august-2017-urgent-action-needed-to-facilitate-insecticides-for-screwworm-infestation-%C3%A2-%C3%A2-%C3%A2-experimental-footrot-studies-in-sheep-%C3%A2-%C3%A2-%C3%A2-oestrus-synchronisation-programs-in-dairy-cattle-%C3%A2-%C3%A2-%C3%A2-neuroendodermal-cyst-in-a-dog-%C3%A2-%C3%A2-%C3%A2-stability-of-morphine
#7
EDITORIAL
https://www.readbyqxmd.com/read/28748232/conservative-vs-radical-approach-for-the-treatment-of-solid-multicystic-ameloblastoma-a-systematic-review-and-meta-analysis-of-the-last-decade
#8
Giuseppe Troiano, Mario Dioguardi, Armando Cocco, Luigi Laino, Gabriele Cervino, Marco Cicciu, Domenico Ciavarella, Lorenzo Lo Muzio
PURPOSE: To examine whether a difference exists in the relapse rate between the conservative and radical approaches after the treatment of solid/multicystic ameloblastoma (SMA), a systematic review of the literature based on evidence of the last decade was performed. MATERIALS AND METHODS: The search strategy incorporated examinations of electronic databases, supplemented by hand searches. A search of four electronic databases, including Ovid MEDLINE, PubMed, EMBASE and Web of Science, was carried out for relevant studies published in the English language from January 2005 to September 2015...
July 25, 2017: Oral Health & Preventive Dentistry
https://www.readbyqxmd.com/read/28734697/prognostic-significance-of-hmsh2-hmsh3-and-hmsh6-expression-in-ameloblastoma
#9
Gleyson Kleber do Amaral-Silva, Celeste Sánchez-Romero, Vivian Petersen Wagner, Manoela Domingues Martins, Hélder Antônio Rebelo Pontes, Eduardo Rodrigues Fregnani, Fernando Augusto Soares, Oslei Paes de Almeida, André Caroli Rocha, Alan Roger Santos-Silva, Felipe Paiva Fonseca, Pablo Agustin Vargas
OBJECTIVE: The aim of this study was to investigate hMutS proteins in developing human tooth, ameloblastomas, and ameloblastic carcinoma and to determine whether the expression of these proteins has any prognostic potential. STUDY DESIGN: Ten cases of developing human tooth, 39 ameloblastomas, and 2 ameloblastic carcinomas were used to determine the distribution of the proteins during the process of carcinogenesis. Simultaneously, another sample of 73 ameloblastomas was arranged in tissue microarray, and their clinical, microscopic, and radiographic features; treatment outcome; presence of BRAF-V600E mutation; and follow-up data were assessed to determine the prognostic relevance of the expression of hMutS (hMSH2, hMSH3, hMSH6) and Ki-67...
June 7, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28729769/recurrence-and-cancerization-of-ameloblastoma-multivariate-analysis-of-87-recurrent-craniofacial-ameloblastoma-to-assess-risk-factors-associated-with-early-recurrence-and-secondary-ameloblastic-carcinoma
#10
Rong Yang, Zheqi Liu, Sandhya Gokavarapu, Canbang Peng, Tong Ji, Wei Cao
OBJECTIVE: The recurrence and progression of ameloblastoma are unpredictable. Therefore, we examined the influence of clinical factors on recurrence time and analyzed the clinical factors associated with early recurrence and cancerization. We then developed a staging system to predict early recurrence and cancerization. METHODS: All of the primary craniofacial ameloblastoma patients treated in Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine were recorded...
June 2017: Chinese Journal of Cancer Research, Chung-kuo Yen Cheng Yen Chiu
https://www.readbyqxmd.com/read/28717292/conservative-management-of-unicystic-ameloblastoma-in-young-patients-a-prospective-single-center-trial-and-review-of-literature
#11
Mitsu Meshram, Lalit Sagarka, Jigar Dhuvad, Sonal Anchlia, Siddharth Vyas, Harsh Shah
AIMS: The study intends to evaluate the clinical outcome of treating young patients of unicystic ameloblastoma, by various conservative treatment modalities such as marsupialization, enucleation with bone curettage and aid in establishing sound treatment guidelines. MATERIALS AND METHODS: A case series of fifteen patients is presented of unicystic ameloblastoma, who presented to our Department over the past 6 years (2010-2015) and conservative method of treatment elected in all the patients...
September 2017: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/28707772/clinicopathological-characteristics-of-desmoplastic-ameloblastoma-a-systematic-review
#12
REVIEW
Rahul Anand, Gargi S Sarode, Sachin C Sarode, Mamatha Reddy, Hemant V Unadkat, Shazia Mushtaq, Revati Deshmukh, Shakira Choudhary, Nitin Gupta, Anjali P Ganjre, Shankargouda Patil
The aim of the present review was to systematically present the clinicopathological data of desmoplastic ameloblastoma (DA) from articles published in the literature. A comprehensive search of the databases (PubMed, Medline, SCOPUS, Web of Science, and Google Scholar) for published articles on DA was conducted. A total of 238 cases were identified and analyzed from 76 published papers. DA showed a slight male predilection (male: female=1.07:1) with a predominance in the fourth and fifth decades of life. Mandibular involvement (52...
July 14, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28706783/the-anecdote-of-viral-etiopathogenia-in-ameloblastoma-and-odontogenic-keratocyst-why-don-t-we-let-it-go
#13
Bacem A E O Khalele
BACKGROUND: Ameloblastoma (AM) and odontogenic Keratocyst (OKC) are destructive odontogenic lesions of the gnathion. Although their exact pathogeneses are not yet totally understood, the viral etiopathogenesis in AM and KCOT has been proposed. True to syndromic keratocystic odontogenic tumor (sKCOT) and non-syndromic OKC is the high recurrence rate. OBJECTIVES: Given that shared pathways trailed by AM and by sKCOT/OKC have been suggested, this study, however, contrasts the expression of AM and OKC for viral antibodies...
May 2017: Journal of Oral Biology and Craniofacial Research
https://www.readbyqxmd.com/read/28706782/immunohistochemical-evaluation-of-podoplanin-in-odontogenic-tumours-cysts-using-anti-human-podoplanin-antibody
#14
Namrata Singhal, Nitin Khanduri, Deepak Kurup, Brijesh Gupta, Pranjan Mitra, Roshani Chawla
BACKGROUND: Odontogenic Cysts & tumors originate through some aberration from the normal pattern of odontogenesis. Ameloblastoma is one of the most frequent intraosseous odontogenic tumors. However it is no longer appropriate to use the diagnosis of ameloblastoma without specifying the type. Varied-clinical entities of ameloblastoma differ in their biologic behaviour. Odontogenic cysts like dentigerous and radicular cysts are less aggressive in nature than odontogenic tumors. Recently, podoplanin commonly used as a lymphatic endothelial marker in cancers has recently been found to play a possible role in odontogenic tumorigenesis also...
May 2017: Journal of Oral Biology and Craniofacial Research
https://www.readbyqxmd.com/read/28699252/mesenchymal-stromal-cell-derived-il-6-promotes-epithelial-mesenchymal-transition-and-acquisition-of-epithelial-stem-like-cell-properties-in-ameloblastoma-epithelial-cells
#15
Chunmiao Jiang, Qunzhou Zhang, Rabie M Shanti, Shihong Shi, Ting-Han Chang, Lee Carrasco, Faizan Alawi, Anh D Le
Epithelial-mesenchymal transition (EMT), a biological process associated with cancer stem-like or cancer-initiating cell (CSC) formation, contributes to the invasiveness, metastasis, drug resistance, and recurrence of the malignant tumors; it remains to be determined whether similar processes contribute to the pathogenesis and progression of ameloblastoma, a benign but locally invasive odontogenic neoplasm. Here, we demonstrated that EMT- and stem cell-related genes were expressed in the epithelial islands of the most common histologic variant subtype, the follicular ameloblastoma...
July 11, 2017: Stem Cells
https://www.readbyqxmd.com/read/28674562/-ameloblastoma-of-the-maxillary-sinus-treated-with-radiation-therapy
#16
Asmaa Chehal, Rosabel Lobo, Asmaa Naim, Ignacio Azinovic
Ameloblastoma is a benign aggressive odontogenic tumor which requires early diagnosis and appropriate treatment. It commonly affects the mandible and radical surgery is the gold standard treatment. We report the case of a patient with ameloblastoma in extremely advanced phase affecting the maxillary sinus who was treated with intensity modulated conformal radiation therapy. Patient's evolution was marked by complete remission maintained after 24 months follow-up. Maxillary ameloblastoma is not well documented in the literature...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28669443/i-125-brachytherapy-guided-by-individual-three-dimensional-printed-plates-for-recurrent-ameloblastoma-of-the-skull-base
#17
J-Y Liu, Q-W Man, Y-Q Ma, B Liu
Ameloblastoma is one of the most common benign odontogenic tumours of the mandible and the maxilla. Wide excision of the tumour is the first choice for treatment (except for unicystic ones). Patients with invaded margins or unresectable lesions may require radiotherapy. Today, permanent implantation of I(125) seeds is widely used in the treatment of cancer of the head and neck. We report a case of recurrent ameloblastoma of the base of the skull that was treated with I(125) brachytherapy. The outcome has been encouraging, with total disappearance of the tumour on positron emission tomography 18 months later...
June 29, 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/28658279/genetic-basis-of-calcifying-cystic-odontogenic-tumors
#18
Akane Yukimori, Yu Oikawa, Kei-Ichi Morita, Chi Thi Kim Nguyen, Hiroyuki Harada, Satoshi Yamaguchi, Kou Kayamori, Akira Yamaguchi, Tohru Ikeda, Kei Sakamoto
Calcifying cystic odontogenic tumors (CCOTs) are benign cystic tumors that form abnormally keratinized ghost cells. Mutations in CTNNB1, which encodes beta-catenin, have been implicated in the development of these tumors, but a causal relationship has not been definitively established. Thus, mutational hot spots in 50 cancer genes were examined by targeted next-generation sequencing in 11 samples of CCOT. Mutations in CTNNB1, but not in other genes, were observed in 10 of 11 cases. These mutations constitutively activate beta-catenin signaling by abolishing the phosphorylation sites Asp32, Ser33, or Ser37, and are similar to those reported in pilomatrixoma and adamantinomatous craniopharyngioma...
2017: PloS One
https://www.readbyqxmd.com/read/28650588/genetic-study-of-the-braf-gene-reveals-a-new-variants-and-high-frequency-of-the-v600e-mutation-among-iranian-ameloblastoma-patients
#19
Maryam Soltani, Mohammad Amin Tabatabaiefar, Zhaleh Mohsenifar, Mohammad Reza Pourreza, Abbas Moridnia, Laleh Shariati, Seyyed Mohammad Razavi
BACKGROUND: Ameloblastoma is a benign, slow-growing, locally invasive tumor. It is one of the most prevalent odontogenic tumors, with an incidence rate of 1% of all oral tumors and approximately 18% of odontogenic tumors. A group of genes has been investigated in patients with ameloblastoma. The BRAF V600E mutation has been implicated as the most common mutation in ameloblastoma. The presence or absence of this mutation has been associated with several clinopathological properties, including location, age at diagnosis, histology, and prognosis...
June 26, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/28639881/suspected-lateral-periodontal-cyst-presenting-concurrently-with-canine-acanthomatous-ameloblastoma-in-a-2-year-old-standard-poodle
#20
Jennifer Tjepkema, Cynthia Bell
Lateral periodontal cysts (LPCs) are odontogenic epithelial cysts composed of nonkeratinized epithelial cells that are in the category of developmental cysts, rather than inflammatory cysts. Lateral periodontal cysts are rare in both people and domestic animals; they are associated with vital teeth and located lateral to a tooth root. Lateral periodontal cysts are typically asymptomatic lesions that are characterized radiographically as a unilocular lucency with well-defined corticated borders. Canine acanthomatous ameloblastoma (CAA) is the most common odontogenic neoplasm in dogs and rarely presents as a cystic lesion...
January 1, 2017: Journal of Veterinary Dentistry
keyword
keyword
36983
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"