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https://www.readbyqxmd.com/read/28545325/mandibular-odontoameloblastoma-in-a-rat-and-a-horse
#1
Brian Murphy, Cynthia Bell, Amanda Koehne, Richard R Dubielzig
Odontoameloblastoma (OA) is a mixed odontogenic tumor that is an ameloblastoma with concurrent histologic evidence of odontoma differentiation. As a mixed tumor, OA is a tripartite lesion comprised of neoplastic odontogenic epithelium, induced dental ectomesenchyme (dental pulp), and mineralized dental matrix. Although rare, OA represents a diagnostic conundrum, as it is histologically closely related to 2 other mixed odontogenic tumors: odontoma (complex and compound) and ameloblastic fibro-odontoma. Herein we describe an OA arising from the mandible of a 4-mo-old Fischer 344 rat that had been exposed in utero to the mutagen ENU (N-ethyl-N-nitrosourea), and a naturally occurring lesion in a 2-y-old Appaloosa horse...
May 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/28512274/glucose-transporter-1-expression-in-odontogenic-keratocyst-dentigerous-cyst-and-ameloblastoma-an-immunohistochemical-study
#2
Alokenath Bandyopadhyay, Abikshyeet Panda, Shyam S Behura, Sujatha Ramachandra, Kailash C Dash, Pallavi Mishra
INTRODUCTION: An array of odontogenic lesions manifest in the maxillofacial region with variable presentations. The biological behavior of lesions, such as odontogenic keratocyst (OKC), dentigerous cyst (DC), and ameloblastoma (AM) always invite debate. Glucose transporter 1 (GLUT-1) is proven to be an indicator of metabolic behavior of several benign and malignant neoplasms. AIM: The purpose of this study was to evaluate the expression of GLUT-1 in OKC, DC, and AM to understand their metabolic behavior...
May 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28503263/spontaneous-peripheral-ameloblastic-odontoma-in-a-male-sprague-dawley-rat
#3
Yinghua Li, Han-Ik Bae, Hak-Soo Kim, Min-Soo Kang, Bo-Ho Gong, Won-Hee Jung, Sranna Lee, Jin-Sook Bae, Kap-Ho Kim, Si-Whan Song, Jae-Hyun Lee, Boo-Hyon Kang
Peripheral ameloblastic odontoma is a rare variant of odontogenic tumor occurring in the extraosseous region. The present report describes a spontaneous tumor in male Sprague-Dawley (SD) rats. The clinically confirmed nodule in the right mandibular region was first observed when the rat was 42 weeks and remained until the terminal sacrifice date when the animal was 48 weeks of age. At necropsy, a well demarcated nodule, approximately 2.5 × 2.0 × 2.0 cm, protruded from the ventral area of the right mandible...
April 2017: Toxicological Research
https://www.readbyqxmd.com/read/28499501/potential-involvement-of-chondroitin-sulfate-a-in-the-pathogenesis-of-ameloblastoma
#4
Xiangjun Li, Hiroshi Kurita, Tiepeng Xiao, Kyou Iijima, Kenji Kurashina, Jun Nakayama
Ameloblastoma is classified as a benign odontogenic tumor characterized by locally invasive behavior and high risk of recurrence. Here, we evaluate a potential role for glycosaminoglycan, a structural component of cell membranes and extracellular matrix, in ameloblstoma pathogenesis. We subjected formalin-fixed, paraffin-embedded tissue sections of 34 cases of ameloblastoma, 10 of odontogenic keratocyst, and 17 of dentigerous cyst to immunohistochemistry using monoclonal antibodies recognizing chondroitin sulfate A (CS-A), heparan sulfate (HS), and keratan sulfate (KS)...
May 9, 2017: Acta Histochemica
https://www.readbyqxmd.com/read/28485021/pattern-of-distribution-of-odontogenic-tumours-in-sub-saharan-africa
#5
Oladunni M Ogundana, Olajumoke Ajibola Effiom, Onatolu Odukoya
OBJECTIVE: To analyse documented reports on odontogenic tumours (OTs) in sub-Saharan Black Africa and to create awareness of the need for more reports on this topic. METHODS: There were 2,186 African cases of OTs presented at the International Association of Oral and Maxillofacial Pathologists (IAOP) Congress (Cape Town, South Africa) in 1998 that were added to 2,198 cases derived from reports published in the scientific literature from 1998 to date. The analysis undertaken included frequency distribution of available data on OTs that was listed in the 2005 World Health Organization (WHO) classification...
May 8, 2017: International Dental Journal
https://www.readbyqxmd.com/read/28479717/granular-cell-ameloblastoma
#6
Yakob Martin, M Sathyakumar, Jeyanthi Premkumar, K T Magesh
A 42-year-female patient presented with a swelling on the left side of the face for the past 10 years. The radiograph shows multilocular radiolucency with evidence of root resorption. Histopathology reveals fibrous connective tissue exhibiting numerous odontogenic epithelial islands with peripheral tall columnar cells showing a reversal of polarity. The center of the island shows stellate reticulum like cells. The connective tissue also shows the presence of extensive coarse granular eosinophilic cells distributed throughout the section...
January 2017: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/28479707/oral-pulse-granuloma-associated-with-ameloblastoma-report-of-a-case-and-review-of-literature
#7
Uma Vasant Datar, Rahul B Patil, Aarti M Mahajan, Sachin Dahivelkar
Oral pulse granuloma (PG) is a rare lesion that presents as a foreign body granulomatous reaction to implanted food particles of plant or vegetable origin. It is classified as a central or a peripheral lesion depending on the location. Rarely, a central oral PG may be associated with a cyst or tumor, thus leading to a deceptive histopathological picture. This is exemplified in the present case of 27-year-old female patient who reported with a swelling on the left posterior region of mandible which was diagnosed as ameloblastoma...
January 2017: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/28479706/disorganized-histomorphology-dentinogenic-ghost-cell-tumor
#8
Cheshta Walia, Bina Kashyap, Sudip Roy
Calcifying odontogenic cyst (COC) is a term used broadly to define lesions which were either cystic/solid in nature. However, a new term defining dentinogenic ghost cell tumor (DGCT), as its neoplastic counterpart, histopathologically showed the presence of dentinoid-like areas, ghost cells and ameloblastomatous-like odontogenic epithelium. This possesses a great challenge to an oral pathologist in diagnosing and differentiating it from solid multicystic ameloblastoma or COCs so as to ensure the biological behavior and pathogenesis behind its multifaceted nature...
January 2017: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/28479687/comparative-immunohistochemical-study-of-bcl-x-in-ameloblastoma-keratocystic-odontogenic-tumor-and-adenomatoid-odontogenic-tumor
#9
Payal Shukla, Sudeendra Prabhu, Maji Jose, B H Sripathi Rao
OBJECTIVES: Since its recognition as a physiologic process associated with tumor, among molecular mechanisms involved in tumor progression, defects in regulation of apoptosis have generated an accelerating volume of research that has sought to elucidate the role of programed cell death in pathogenesis and treatment of various tumors. Therefore, this study was performed to understand better the diverse biological profile of epithelial odontogenic tumors with the help of immunohistochemical expression of Bcl-X protein...
January 2017: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/28472562/prevalence-of-odontogenic-lesions-among-the-kanpur-population-an-institutional-study
#10
Amrita Raj, Gayathri Ramesh, Ramesh Nagarajappa, Amit Pandey, Ankita Raj
BACKGROUND: The frequency and incidence of odontogenic cysts and tumors are controversial and depends in the geographic location. These lesions have great clinical and histopathological diversity, and reflect a need for epidemiological profile to be considered when these lesions are studied. AIM: The purpose of this study was to determine the prevalence of odontogenic cysts and tumors over a period of 10 years and to compare with other data reported around the world...
May 2017: Journal of Experimental Therapeutics & Oncology
https://www.readbyqxmd.com/read/28469123/acanthomatous-ameloblastoma-in-anterior-mandibular-region-of-a-young-patient-a-rare-case-report
#11
Sridevi Ugrappa, Ajay Jain, Neeraj Kumar Fuloria, Shivkanya Fuloria
Ameloblastoma is the most known of the epithelial odontogenic benign tumor. It is slow growing and locally aggressive in nature and most commonly seen in the posterior mandible. Various histopathological variants exist, among which acanthomatous type of ameloblastoma is one of the rarest types. Acanthomatous ameloblastoma is usually seen in older aged human population and most commonly reported in canine region of dogs in literature. Here, we report a rare case of acanthomatous ameloblastoma in a young male patient involving mandibular anterior region crossing the midline with recurrence over a period of 2 years of follow-up after surgical resection...
April 2017: Annals of African Medicine
https://www.readbyqxmd.com/read/28468204/ameloblastoma-in-a-patient-with-williams-syndrome-and-use-of-fibular-flap
#12
Fatma Betul Tuncer, Bulent Sacak, Zeynep Deniz Akdeniz, Ozhan Celebiler
No abstract text is available yet for this article.
May 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28462196/aggressive-unicystic-ameloblastoma-affecting-the-posterior-mandible-late-diagnosis-during-orthodontic-treatment
#13
Sérgio Lúcio Pereira de Castro Lopes, Isadora Luana Flores, Thiago de Oliveira Gamba, Rivea Ines Ferreira-Santos, Mari Eli Leonelli de Moraes, Aline Alvarez Cabello, Paula Nascimento Moutinho
Maxillofacial images must be examined to find pathologies not identified during clinical examination. Unicystic ameloblastoma (UA) extending to the mandibular body and ramus was neglected on initial panoramic radiographic examination. After orthodontic therapy, a huge lesion was observed clinically and through imaging exams. After the conservative surgery, no recurrence was observed during five years of follow-up. This case emphasized the need for careful evaluation of patient images focusing on the oral diagnosis before any dental treatment planning, including orthodontic therapy...
April 2017: Journal of the Korean Association of Oral and Maxillofacial Surgeons
https://www.readbyqxmd.com/read/28454892/dna-damage-response-activation-and-cell-cycle-dysregulation-in-infiltrative-ameloblastomas-a-proposed-model-for-ameloblastoma-tumor-evolution
#14
Marina Gonçalves Diniz, Bruna Viana Antonini Guimarães, Núbia Braga Pereira, Grazielle Helena Ferreira de Menezes, Carolina Cavalieri Gomes, Ricardo Santiago Gomez
No abstract text is available yet for this article.
April 25, 2017: Experimental and Molecular Pathology
https://www.readbyqxmd.com/read/28444096/off-label-use-of-rhbmp-2-as-bone-regeneration-strategies-in-mandibular-ameloblastoma-unicystic
#15
Henrique Celestino Lima E Silva, Adonai Peixoto Cheim, Roberto Moreno, Sérgio Luis de Miranda
Jawbone reconstruction after tumor resection is one of the most challenging clinical tasks for maxillofacial surgeons. Osteogenic, osteoinductive, osteoconductive and non-antigenic properties of autogenous bone place this bone as the gold standard for solving problems of bone availability. However, the need for a second surgical site to harvest the bone graft increases significantly both the cost and the morbidity associated with the reconstructive procedures. Bone grafting gained an important tool with the discovery of bone morphogenetic proteins in 1960...
January 2017: Einstein
https://www.readbyqxmd.com/read/28431236/unicystic-ameloblastoma-revisited-comparison-of-massachusetts-general-hospital-outcomes-with-original-robinson-and-martinez-report
#16
Anne-Frédérique Chouinard, Zachary S Peacock, William C Faquin, Leonard B Kaban
PURPOSE: Robinson and Martinez established unicystic ameloblastoma (UA) as a distinct pathologic entity in 1977. By use of their original description, the aim of this study was to compare the clinical presentation and outcomes of UA treated at Massachusetts General Hospital (MGH) with outcomes reported in the original article. PATIENTS AND METHODS: This was a retrospective cohort study of MGH patients treated for UA during a 15-year period. Patients were included if they had a confirmed clinical and histologic diagnosis of UA...
March 27, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28390135/comparative-histological-and-immunohistochemical-study-of-ameloblastomas-and-ameloblastic-carcinomas
#17
M Martínez-Martínez, A Mosqueda-Taylor, R Carlos-Bregni, F-R Pires, W Delgado-Azanero, R Neves-Silva, B Aldape-Barrios, O Paes-de Almeida
BACKGROUND: This study aimed to compare the histological and immunohistochemical characteristics of ameloblastomas (AM) and ameloblastic carcinomas (AC). MATERIAL AND METHODS: Fifteen cases of AM and 9 AC were submitted to hematoxilin and eosin (H&E) and immunohistochemical analysis with the following antibodies: cytokeratins 5,7,8,14 and 19, Ki-67, p53, p63 and the cellular adhesion molecules CD138 (Syndecan-1), E-cadherin and β-catenin. The mean score of the expression of Ki-67 and p53 labelling index (LIs) were compared between the groups using the t test...
May 1, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/28384994/a-rare-case-of-adenomatoid-odontogenic-tumour-with-unicystic-ameloblastoma
#18
Vidya Karnam Sathyanarayana, Huldah Srigiri, Mounija Cheemalavagupalli, Sairam Vankadara, Geetha Malika
No abstract text is available yet for this article.
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28340422/the-clinicopathologic-relevance-of-reck-gene-polymorphisms-in-ameloblastoma
#19
Xudong Zhang, Jie Wang, Huijuan Liu, Yanning Zhang, Fusheng Dong
OBJECTIVE: To investigate the relationship between RECK gene polymorphisms and the clinicopathologic features of ameloblastoma. DESIGN: Normal gingival mucosa specimens were obtained from 10 healthy volunteers. Ameloblastomas were surgically removed from 30 patients and part of the tumor specimens were used to detect RECK gene polymorphisms by using PCR-single-strand conformation polymorphism (PCR-SSCP) and DNA sequencing analysis. Expression of RECK and MMP-9 protein was measured using western blot...
July 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28316917/a-comparative-study-of-syndecan-1-expression-in-different-odontogenic-tumors
#20
Shahroo Etemad-Moghadam, Mojgan Alaeddini
BACKGROUND: Expression of various cellular/molecular factors change during the course of tumor formation from odontogenic tissues of the tooth germ. Evaluation of these factors can help provide a better perception of the tumorigenesis and biologic behavior of odontogenic tumors (OTs). Syndecan-1 is a heparan sulfate proteoglycan which has not been extensively investigated in these lesions. The objective of the present study was to assess the immunohistochemical expression of CD138 in adenomatoid odontogenic tumor (AOT), ameloblastic fibroma (AF) and odontogenic myxoma (OM) and to compare it with ameloblastoma and keratocystic odontogenic tumor (KCOT)...
January 2017: Journal of Oral Biology and Craniofacial Research
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