keyword
https://read.qxmd.com/read/38528998/correction-carcinoma-ex-ameloblastoma-of-the-mandible-a-rare-case-report
#1
Prachurya Dakshinakabat, Abikshyeet Panda, Pallavi Mishra, Monalisha Mahapatra, Lipsa Bhuyan
[This corrects the article DOI: 10.7759/cureus.49536.].
March 2024: Curēus
https://read.qxmd.com/read/38519948/curettage-combined-with-decompression-for-the-treatment-of-ameloblastoma-in-children-report-of-two-cases
#2
JOURNAL ARTICLE
Chen Xu, Yuhua Hu, Yuhuan Sun, Qiang Shao, Yonghai Song, Jie He
BACKGROUND: Ameloblastoma (AM) is the most common benign odontogenic tumor, which is more often detected in the mandible than maxilla, especially the mandibular body and mandibular angle. Pediatric AM is a rare disease, especially in patients aged 10 and younger. Compared with the mainstream osteotomy and reconstructive surgery for adult ameloblastoma, there is more room for discussion in the treatment of pediatric ameloblastoma. The postoperative functional and psychological influence can not be ignored...
March 22, 2024: BMC Oral Health
https://read.qxmd.com/read/38516497/cholesterol-granuloma-from-a-developmental-odontogenic-cyst-a-report-of-a-rare-case-and-a-literature-review
#3
Ashwin Pattabhi, Sneha Pendem, Dharini S, Monal Yuwanati, Murugesan Krishnan
Dentigerous cysts are the second most common developmental odontogenic cysts that develop around the crown of unerrupted teeth with the maxillary canine region being one of the common sites of occurrence. The cystic lining of this lesion has been shown to develop into ameloblastoma, Muco epidermoid carcinoma, and squamous cell carcinomas. However, the development of cholesterol granuloma (CG) in the cystic lining of a dentigerous cyst is extremely rare. CG is a histological observation distinguished by the presence of a conglomeration of connective tissue and granulation tissue...
February 2024: Curēus
https://read.qxmd.com/read/38504671/maxillary-ameloblastoma-with-local-recurrence-orbital-invasion-and-systemic-metastases-a-case-report-and-review-of-the-literature
#4
Taylor J Linaburg, Javiera Araya, César A Briceño
INTRODUCTION: Maxillary ameloblastoma is a rare, slow-growing odontogenic tumor that can recur after surgical excision, be locally aggressive, and rarely develop systemic metastases. We describe the course and management of a patient with recurrent maxillary ameloblastoma with orbital invasion and systemic metastases, the fourth case of its kind to be described in the literature. CASE PRESENTATION: A 50-year-old female presented with left hyperglobus. A diagnosis of maxillary ameloblastoma was made based on biopsy and neuroimaging with MRI and CT...
2024: Case Reports in Ophthalmology
https://read.qxmd.com/read/38504068/braf-p-v600e-mutational-status-does-not-correlate-with-biological-behavior-in-conventional-ameloblastomas-a-disease-free-survival-analysis
#5
JOURNAL ARTICLE
Allan Vinícius Martins-de-Barros, Fábio Andrey da Costa Araújo, Tatiane Fonseca Faro, Arthur Alves Thomaz de Aquino, Adauto Gomes Barbosa Neto, Helker Albuquerque Macedo da Silva, Elker Lene Santos de Lima, Maria Tereza Cartaxo Muniz, Emanuel Dias de Oliveira E Silva, Marianne de Vasconcelos Carvalho
BACKGROUND: Dysregulation of the MAPK pathway appears to exert a pivotal role in the pathogenesis of ameloblastomas, since BRAF p.V600E has been reported in over 65% of the tumors. Therefore, the purpose of this study was to investigate whether the BRAF p.V600E is related to biological behavior and disease-free survival in patients with conventional ameloblastomas. METHODS: This is a retrospective cohort study based on the STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) recommendations...
March 19, 2024: Head and Neck Pathology
https://read.qxmd.com/read/38494972/-braf-v600e-expression-in-ameloblastomas-ameloblastic-carcinomas-and-cysts
#6
JOURNAL ARTICLE
Jing Pei, Lin Zhang, Yun-Xiang Jia, Wei-Hua Chen
PURPOSE: To investigate protein and genetic status of BRAF V600E in ameloblastomas, ameloblastic carcinomas and cysts, and to explore if recurrence and malignant transformation of ameloblastomas depends on BRAF status. METHODS: Twenty cysts, 25 primary ameloblastomas, 25 recurrent ameloblastomas and 8 ameloblastic carcinomas were analysed by immunohistochemistry, and 2 cysts, 5 primary ameloblatomas, 5 recurrent ameloblastomas, 3 atypical ameloblastomas and 6 ameloblastic carcinomas were analysed by quantitative real-time PCR(qPCR)...
December 2023: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://read.qxmd.com/read/38494749/it-was-not-possible-to-detect-braf-v600e-mutation-in-circulating-cell-free-dna-from-patients-with-ameloblastoma-a-diagnostic-accuracy-study
#7
JOURNAL ARTICLE
Allan Vinícius Martins-de-Barros, Fábio Andrey da Costa Araújo, Ana Maria Ipólito Barros, Elenisa Glaucia Ferreira Dos Santos, Adauto Gomes Barbosa Neto, Helker Albuquerque Macedo da Silva, Elker Lene Santos de Lima, Maria Tereza Cartaxo Muniz, Riedel Frota Sá Nogueira Neves, Rômulo Oliveira de Hollanda Valente, Emanuel Dias de Oliveira E Silva, Marianne de Vasconcelos Carvalho
BACKGROUND: The objective of this study is to evaluate the diagnostic accuracy of plasma-based liquid biopsy for the detection of the BRAF V600E mutation in circulating cell-free DNA from patients with ameloblastoma. METHODS: This is a prospective diagnostic accuracy study conducted based on the Standards for Reporting Diagnostic Accuracy recommendations. The index test was the plasma-based liquid biopsy, whereas the reference standard was the conventional tissue biopsy...
March 17, 2024: Journal of Oral Pathology & Medicine
https://read.qxmd.com/read/38486378/rare-case-of-recurrent-adamantinoma-of-the-tibia-limited-efficacy-of-pazopanib-as-a-standalone-treatment
#8
JOURNAL ARTICLE
Mahmoud Elshenawy, Sarah Khaled Aldahoul, Abduljalil Mohamed El-Sibai, Alaa Hamad, Tarek Ziad Arabi, Saleha Abdul Rab, Ahmed Badran, Tariq Alzaid, Belal Nedal Sabbah, Jean Paul Atallah
BACKGROUND Adamantinoma is a rare low-grade malignant bone tumor, usually found in the tibial diaphysis and metaphysis, with histological similarities to mandibular ameloblastoma. The most effective treatment of recurrent adamantinoma is not yet clear. This report is of a 22-year-old woman with recurrent tibial adamantinoma treated with the tyrosine kinase inhibitor pazopanib. CASE REPORT We report the case of a 22-year-old woman who was referred to our center for a suspicious bone lesion in the right tibia...
March 15, 2024: American Journal of Case Reports
https://read.qxmd.com/read/38476605/exploring-protein-profiles-and-hub-genes-in-ameloblastoma
#9
JOURNAL ARTICLE
Sirima Sanguansin, Sudaporn Kengkarn, Boworn Klongnoi, Suthipong Chujan, Sittirak Roytrakul, Nakarin Kitkumthorn
Ameloblastoma (AM) is a prominent benign odontogenic tumor characterized by aggressiveness, likely originating from tooth-generating tissue or the dental follicle (DF). However, proteomic distinctions between AM and DF remain unclear. In the present study, the aim was to identify the distinction between AM and DF in terms of their proteome and to determine the associated hub genes. Shotgun proteomics was used to compare the proteomes of seven fresh-frozen AM tissues and five DF tissues. Differentially expressed proteins (DEPs) were quantified and subsequently analyzed through Gene Ontology-based functional analysis, protein-protein interaction (PPI) analysis and hub gene identification...
April 2024: Biomedical Reports
https://read.qxmd.com/read/38476514/virtual-surgical-planning-in-condyle-reconstruction-of-posterior-mandibulectomy-defects
#10
Katherine C Benedict, Ignacio Velasco Martinez, Benjamin McIntyre
BACKGROUND: Ameloblastoma is a rare odontogenic tumor most commonly located within the mandible. These tumors can grow to massive proportions and result in malocclusion. Segmental mandibulectomy and reconstruction with an osteocutaneous free flap are frequently required. Virtual surgical planning (VSP) aids the surgeon in creating precise anatomic reconstruction when there is preoperative malocclusion due to tumor size. In this study we seek to further examine reconstruction of posterior mandibulectomy defects inclusive of condylar resection...
2024: Eplasty
https://read.qxmd.com/read/38467107/maxillary-mass-in-a-1-year-old-feline
#11
JOURNAL ARTICLE
Allison M Groff, Peter J Welsh, Colleen M Lynch, Ryan Oliveira, Boel Fransson
No abstract text is available yet for this article.
March 8, 2024: Journal of the American Veterinary Medical Association
https://read.qxmd.com/read/38461076/proteomics-study-of-bone-tissue-around-ameloblastoma-and-the-potential-mechanism-of-cd36-in-bone-remodelling
#12
JOURNAL ARTICLE
Chen-Xi Zhang, Qi-Wen Man
Ameloblastoma (AM) is characterised by local aggressiveness and bone resorption. To our knowledge, the proteomic profile of bone adjacent to AM has not previously been explored. We therefore looked at the differential proteins in cancellous bone (CB) adjacent to AM and normal CB from the mandible. CB proteins were extracted, purified, quantified, and analysed by liquid chromatography-mass spectrometry (LC-MS) using samples from five patients with AM. These proteins were further investigated using gene ontology for additional functional annotation and enrichment...
January 4, 2024: British Journal of Oral & Maxillofacial Surgery
https://read.qxmd.com/read/38459319/ameloblastoma
#13
Paul Hellyer
No abstract text is available yet for this article.
March 2024: British Dental Journal
https://read.qxmd.com/read/38458909/which-devices-can-be-used-to-decompress-odontogenic-cystic-lesions-in-the-oral-cavity-a-systematic-review
#14
REVIEW
Vinícius Teixeira Silva, Wladimir Gushiken de Campos, Caroline Leone, Fábio de Abreu Alves, Celso Augusto Lemos
Odontogenic cysts are bony lesions in the jaws that can reach large sizes. Decompression, a technique that helps in their surgical treatment, aims to reduce their size. We aimed to conduct a systematic review of the main types of device used for the decompression of odontogenic cysts and to analyse the indications, types, advantages, and disadvantages of the devices used. We searched PubMed, Science Direct, LILACS, EMBASE, and Web of Science until February 2023, with no time restriction. We considered studies with a minimum of 10 patients published only in English, those that reported cases and case series, randomised clinical trials of the decompression of odontogenic cysts, and the types of devices used during the decompression period...
January 4, 2024: British Journal of Oral & Maxillofacial Surgery
https://read.qxmd.com/read/38454226/gorlin-syndrome-a-comprehensive-evaluation-of-skin-findings
#15
JOURNAL ARTICLE
Tuğba Atcı, Elizaveta Melnicova, Can Baykal
OBJECTIVE: Although Gorlin syndrome has rich skin findings, there is limited information about their subtypes, features specific to this genodermatosis, and relationships with each other. MATERIALS AND METHODS: The demographic characteristics as well as cutaneous and extracutaneous findings of consecutive Gorlin syndrome patients diagnosed during 23 years were evaluated retrospectively. The relationship between palmoplantar pitting and basal cell carcinoma (BCC) in this localization and the relationship between odontogenic keratocysts (OKCs) and epidermoid cysts were investigated...
March 2024: Turkish archives of pediatrics
https://read.qxmd.com/read/38445604/proceedings-of-the-2023-division-of-translational-toxicology-satellite-symposium
#16
JOURNAL ARTICLE
Erin M Quist, Ronnie Chamanza, Amanda J Martinot, Allison Boone, Gregory A Krane, Martha E Hensel, Shawn V Lennix
The 2023 annual Division of Translational Toxicology (DTT) Satellite Symposium, entitled "Pathology Potpourri," was held in Summerlin, Nevada, at the Society of Toxicologic Pathology's 41st annual meeting. The goal of this symposium was to present and discuss challenging diagnostic pathology and/or nomenclature issues. This article presents summaries of the speakers' talks along with select images that were used by the audience for voting and discussion. Various lesions and topics covered during the symposium included induced and spontaneous neoplastic and nonneoplastic lesions in the mouse liver, infectious and proliferative lesions in nonhuman primates, interesting presentations of mononuclear cell infiltrates in various animal models and a complex oral tumor in a rat...
March 6, 2024: Toxicologic Pathology
https://read.qxmd.com/read/38440659/clear-and-spindle-cell-dedifferentiation-in-ameloblastic-carcinoma-a-case-report-on-a-uncommon%C3%A2-phenomenon
#17
JOURNAL ARTICLE
Sharon John, S Ramya, Saloni Verma, Fahad M Samadi, Shalini Gupta
Ameloblastic carcinoma is a rare malignant neoplasm with characteristic histopathological features that are directed towards an aggressive surgical approach than benign odontogenic lesions. It affects people of all ages, mostly in the posterior mandible, without a preference for race or gender. De novo cancer is one of its primary types, while the second type is defined as a malignant change from an antecedent case of benign ameloblastoma. The rapid progression of molecular biology led to the revelation that ameloblastoma contains a BRAF-V600E genetic mutation over 60%...
February 2024: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/38440613/metamorphosis-of-dentigerous-cyst-a-case-series-with-insight-into-molecular-profiling
#18
JOURNAL ARTICLE
Sharon John, Ayushi Jain, Eram Khan, Shalini Gupta, Shaleen Chandra
The objective of this study was to review the clinical, radiologic, and histologic aspects of cases of dentigerous cysts metamorphosing into different entities along with comments on the molecular factors involved in the process. A series comprising 8 cases of dentigerous cysts was performed retrospectively along with a comprehensive literature review. Two cases of dentigerous cyst converting into mucous metaplasia were included, out of which one case was transformed into ameloblastoma after a year. The other two cases were reported as acanthomatous and unicystic ameloblastoma, whereas four transitioned to AOT...
February 2024: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/38440574/literature-review-case-presentation-and-management-of-non-ossifying-fibroma-of-right-angle-of-mandible-more-than-just-a-cortical-defect
#19
JOURNAL ARTICLE
Deepak Pandiar, P Anbumani, Reshma Poothakulath Krishnan
Non-ossifying fibroma (NOF) of jaw bones are rare. While NOF is the most common benign bone tumor of long bones with pathognomonic radiological features and bear a tendency for self-regression, gnathic NOF appears to be comparatively larger in size and behave more aggressively. A 16 years old female patient reported with painless swelling of the right side of the face of 4 months duration. Radiographic analysis showed a unilocular radiolucent lesion of right angle of the mandible with ill-defined margins, cortical perforation and thinning of inferior border...
February 2024: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/38440520/collision-tumour-comprising-desmoplastic-ameloblastoma-and-squamous-odontogenic-tumour-in-the-anterior-maxilla-a-case-report
#20
JOURNAL ARTICLE
Mayukh Misra, Chirantan Maity, Ankita Saraf, Sayani Shome, Rajarshi Banerjee, Arup Kumar Ghosh
Collision tumours, characterized by the simultaneous occurrence of two distinct neoplasms within the same anatomical site, are exceedingly rare in oral pathology. This case report presents an uncommon collision tumour involving desmoplastic ameloblastoma and squamous odontogenic tumour in the anterior maxilla of a 52-year-old male from the Indian population. Desmoplastic ameloblastoma is a variant of ameloblastoma known for its unique histopathological features, while squamous odontogenic tumour is a benign epithelial odontogenic tumour with distinctive clinical behaviour...
February 2024: Indian Journal of Otolaryngology and Head and Neck Surgery
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