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https://www.readbyqxmd.com/read/28216134/spatial-distribution-and-composition-of-aliphatic-hydrocarbons-polycyclic-aromatic-hydrocarbons-and-hopanes-in-superficial-sediments-of-the-coral-reefs-of-the-persian-gulf-iran
#1
Ranjbar Jafarabadi Ali, Riyahi Bakhtiari Alireza, Aliabadian Mansour, Shadmehri Toosi Amirhossein
This study is the first quantitative report on petroleum biomarkers from the coral reefs systems of the Persian Gulf. 120 reef surface sediment samples from ten fragile coral reef ecosystems were collected and analyzed for grain size, biogenic elements, elemental ratios, and petroleum biomarkers (n-alkanes, PAHs(1) and Hopanes) to assess the sources and early diagenesis of sedimentary organic matter. The mean grain size of the reef sediments ranged from 13.56 to 37.11% (Clay), 26.92 to 51.73% (Sand) and 35...
February 16, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28152751/identifying-avoidable-terminal-oncology-icu-hospitalizations
#2
Andrew Hantel, Blase N Polite
: 56 Background: Eight percent of cancer patients expire in the ICU. There is no association between spending on aggressive end of life (EOL) care and survival outcomes. This aggressive care is also associated with reduced quality of life for patients and families. The National Quality Forum endorses the number of patients admitted to the ICU in the last 30 days of life as a quality of care measure. Our hypothesis is that a significant number of oncology patients suffer avoidable terminal ICU hospitalizations...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28143631/automatic-biological-cell-counting-using-a-modified-gradient-hough-transform
#3
Emmanuel Denimal, Ambroise Marin, Stéphane Guyot, Ludovic Journaux, Paul Molin
We present a computational method for pseudo-circular object detection and quantitative characterization in digital images, using the gradient accumulation matrix as a basic tool. This Gradient Accumulation Transform (GAT) was first introduced in 1992 by Kierkegaard and recently used by Kaytanli & Valentine. In the present article, we modify the approach by using the phase coding studied by Cicconet, and by adding a "local contributor list" (LCL) as well as a "used contributor matrix" (UCM), which allow for accurate peak detection and exploitation...
February 1, 2017: Microscopy and Microanalysis
https://www.readbyqxmd.com/read/28140544/h%C3%A3-ufigkeit-und-muster-der-tumorerkennung-nach-selbstuntersuchung-bei-mittel-bis-hochrisiko-melanompatienten
#4
Anca Sindrilaru, Vera Neckermann, Thomas Eigentler, Panagiotis Kampilafkos, Diana Crisan, Nicolai Treiber, Karin Scharffetter-Kochanek, Lars Alexander Schneider
HINTERGRUND UND ZIELSETZUNG: Die Frage, wie oft Melanompatienten mit Mittel- bis Hochrisikomelanomen den Tumor bemerken und welche Eigenerkennungsmuster existieren ist bislang nicht beantwortet. PATIENTEN UND METHODEN: Wir haben eine retrospektive Studie an Melanompatienten durchgeführt, die sich zwischen 2004 und 2008 einer Sentinellymphknotenbiopsie unterzogen haben,. Der Fragebogen wurde von 127 der insgesamt 133 Patienten ausgefüllt. ERGEBNISSE: 25 % bemerkten den Tumor überhaupt nicht...
January 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/28140538/self-detection-frequency-and-recognition-patterns-in-medium-to-high-risk-cutaneous-melanoma-patients
#5
Anca Sindrilaru, Vera Neckermann, Thomas Eigentler, Panagiotis Kampilafkos, Diana Crisan, Nicolai Treiber, Karin Scharffetter-Kochanek, Lars Alexander Schneider
BACKGROUND AND OBJECTIVES: The question of how frequently patients with medium to high-risk melanomas become aware of their tumors and which self-detection patterns exist remains unanswered. PATIENTS AND METHODS: We conducted a retrospective survey of melanoma patients who had undergone sentinel node biopsy between 2004 and 2008. One hundred twenty-seven out of a total of 133 patients completed the questionnaire. RESULTS: Twenty-five percent of patients had not noticed their tumors at all...
January 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/28124782/azohydromonas-riparia-sp-nov-and-azohydromonas-ureilytica-sp-nov-isolated-from-a-riverside-soil-in-south-korea
#6
Tuan Manh Nguyen, Jaisoo Kim
White and pale yellow coloured bacteria were isolated from the riverside soil, Daejeon, South Korea, and were designated UCM-11(T), UCM-F25, and UCM-80(T). We found that all strains were able to reduce nitrate, and the cells were aerobic and motile. The DNA G+C contents of UCM-11(T), UCM-F25, and UCM-80(T) were between 68.9 to 71.2 mol% and the main ubiquinone was observed as Q-8. Based on16S rRNA gene sequences, strains UCM-11(T) and UCM-F25 were found to closely match with Azohydromonas australica IAM 12664(T) (98...
January 26, 2017: Journal of Microbiology / the Microbiological Society of Korea
https://www.readbyqxmd.com/read/28122790/cytokine-profiles-in-malawian-children-presenting-with-uncomplicated-malaria-severe-malarial-anemia-and-cerebral-malaria
#7
Wilson L Mandala, Chisomo L Msefula, Esther N Gondwe, Mark T Drayson, Malcolm E Molyneux, Calman A MacLennan
Pro-inflammatory cytokines are involved in clearance of Plasmodium falciparum, and very high levels of these cytokines have been implicated in the pathogenesis of severe malaria. In order to determine how cytokines vary with disease severity and syndrome, we enrolled Malawian children presenting with cerebral malaria (CM), severe malarial anaemia (SMA) and uncomplicated malaria (UCM), and healthy controls. We analysed serum cytokine concentrations in acute infection, and in convalescence. With the exception of IL-5, cytokine concentrations were highest in acute CM, followed by SMA, and were only mildly elevated in UCM...
January 25, 2017: Clinical and Vaccine Immunology: CVI
https://www.readbyqxmd.com/read/28074874/modeling-confirmation-bias-and-polarization
#8
Michela Del Vicario, Antonio Scala, Guido Caldarelli, H Eugene Stanley, Walter Quattrociocchi
Online users tend to select claims that adhere to their system of beliefs and to ignore dissenting information. Confirmation bias, indeed, plays a pivotal role in viral phenomena. Furthermore, the wide availability of content on the web fosters the aggregation of likeminded people where debates tend to enforce group polarization. Such a configuration might alter the public debate and thus the formation of the public opinion. In this paper we provide a mathematical model to study online social debates and the related polarization dynamics...
January 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/27999535/dynamic-determinants-of-the-uncontrolled-manifold-during-human-quiet-stance
#9
Yasuyuki Suzuki, Hiroki Morimoto, Ken Kiyono, Pietro G Morasso, Taishin Nomura
Human postural sway during stance arises from coordinated multi-joint movements. Thus, a sway trajectory represented by a time-varying postural vector in the multiple-joint-angle-space tends to be constrained to a low-dimensional subspace. It has been proposed that the subspace corresponds to a manifold defined by a kinematic constraint, such that the position of the center of mass (CoM) of the whole body is constant in time, referred to as the kinematic uncontrolled manifold (kinematic-UCM). A control strategy related to this hypothesis (CoM-control-strategy) claims that the central nervous system (CNS) aims to keep the posture close to the kinematic-UCM using a continuous feedback controller, leading to sway patterns that mostly occur within the kinematic-UCM, where no corrective control is exerted...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27940042/interrelationship-among-steroid-hormones-energetics-and-vocalisation-in-the-bombay-night-frog-nyctibatrachus-humayuni
#10
A M Joshi, E J Narayan, N P Gramapurohit
In vertebrates, the increase in plasma androgens and corticosteroids is essential for the expression of reproductive behaviour. In male anurans, the interaction between hypothalamus-pituitary-gonadal and hypothalamus-pituitary-interrenal axes plays a pivotal role in calling behaviour and energy mobilisation through the secretion of testosterone and corticosterone respectively. To explain the association among body condition, testosterone, corticosterone and calling behaviour the energetic-hormone-vocalisation (EHV) model has been proposed...
December 8, 2016: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/27936996/a-review-of-benefits-of-cord-milking-over-delayed-cord-clamping-in-the-preterm-infant-and-future-directions-of-research
#11
Azif Safarulla
PURPOSE OF REVIEW: The recommended method of handling the umbilical cord has undergone a complete 360 degree turn over the years and current knowledge and research has led the direction to delayed clamping and cord milking. This practice has also been supported by American College of Obstetrics and Gynecology [ACOG] in 2012. This review is a summary of current evidence on delayed cord clamping [DCC], umbilical cord milking [UCM], and comparison between the two and future directions. RECENT FINDINGS: Multiple studies have been published establishing the safety of umbilical cord milking...
December 11, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27920723/sex-dependent-anti-stress-effect-of-an-%C3%AE-5-subunit-containing-gabaa-receptor-positive-allosteric-modulator
#12
Sean C Piantadosi, Beverly J French, Michael M Poe, Tamara Timić, Bojan D Marković, Mohan Pabba, Marianne L Seney, Hyunjung Oh, Beverley A Orser, Miroslav M Savić, James M Cook, Etienne Sibille
Rationale: Current first-line treatments for stress-related disorders such as major depressive disorder (MDD) act on monoaminergic systems and take weeks to achieve a therapeutic effect with poor response and low remission rates. Recent research has implicated the GABAergic system in the pathophysiology of depression, including deficits in interneurons targeting the dendritic compartment of cortical pyramidal cells. Objectives: The present study evaluates whether SH-053-2'F-R-CH3 (denoted "α5-PAM"), a positive allosteric modulator selective for α5-subunit containing GABAA receptors found predominantly on cortical pyramidal cell dendrites, has anti-stress effects...
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27917785/dipyrone-ameliorates-behavioural-changes-induced-by-unpredictable-chronic-mild-stress-gender-differences
#13
Olcay E Kiroğlu, Kübra E Demirkol, Fatih Berktaş, Arash A Yegani, Ayşegül Kirpik, Erkan Maytalman, Mahmut Ünverdi, Fazilet Aksu
PURPOSE: Antidepressant effects of analgesics have been investigate in both clinical and experimental studies. The purpose of this study was to investigate if the analgesic-antipyretic drug, dipyrone, also had antidepressant-like effects. METHODS: Depression-like effects were investigated in an unpredictable chronic mild stress (UCMS) model in both male and female mice. Cage changes, light-dark cycle reversal, cage tilting, wet floor, empty cage, foreign material on the floor and predator sounds were used to induce light stress at different times for six weeks...
December 1, 2016: Clinical and Investigative Medicine. Médecine Clinique et Experimentale
https://www.readbyqxmd.com/read/27904425/association-of-thyroid-profile-and-prolactin-level-in-patient-with-secondary-amenorrhea
#14
Sujata Shrestha, Sunita Neupane, Narayan Gautam, Raju Kumar Dubey, Amit Chandra Jha, Nilesh Raj Doshi, Archana Jayan
BACKGROUND: Amenorrhea is the absence of menstrual periods. It has multiple social consequences as it may leads to infertility. This case control study was conducted for determining the association of thyroid hormones with hyperprolactinemia in patient with amenorrhea. METHODS: We investigated 50 women with diagnosed cases of secondary amenorrhoea, who attended UCMS hospital, for hormonal evaluations. Fifty two healthy women were taken as the controls. The thyroid dysfunction and serum prolactin level were reviewed in cases and in the controls...
September 2016: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/27904147/penile-constitutive-nitric-oxide-synthase-expression-in-rats-exposed-to-unpredictable-chronic-mild-stress-role-of-inflammation
#15
T D Şahin, Y Yazır, T Utkan, S S Göçmez, D Bayramgürler
Chronic psychological stress cause erectile dysfunction (ED). Considering recent evidence that tumor necrosis factor-α (TNF-α) levels are increased in serum of patients with ED, the present study investigated the effects of infliximab (a TNF-α blocker) on endothelial nitric oxide synthase (eNOS) and neuronal NOS (nNOS) immunoreactivity of rat penile corpus cavernosum in unpredictable chronic mild stress (UCMS). Male adult rats were randomly divided into three groups (n=8 per group): Control, UCMS and UCMS+infliximab...
December 1, 2016: International Journal of Impotence Research
https://www.readbyqxmd.com/read/27828964/chronic-treatment-with-the-ido1-inhibitor-1-methyl-d-tryptophan-minimizes-the-behavioural-and-biochemical-abnormalities-induced-by-unpredictable-chronic-mild-stress-in-mice-comparison-with-fluoxetine
#16
Anthony Laugeray, Jean-Marie Launay, Jacques Callebert, Oguz Mutlu, Gilles J Guillemin, Catherine Belzung, Pascal R Barone
We demonstrated that confronting mice to the Unpredictable Chronic Mild Stress (UCMS) procedure-a validated model of stress-induced depression-results in behavioural alterations and biochemical changes in the kynurenine pathway (KP), suspected to modify the glutamatergic neurotransmission through the imbalance between downstream metabolites such as 3-hydroxykynurenine, quinolinic and kynurenic acids. We showed that daily treatment with the IDO1 inhibitor 1-methyl-D-tryptophan partially rescues UCMS-induced KP alterations as does the antidepressant fluoxetine...
2016: PloS One
https://www.readbyqxmd.com/read/27818278/effect-of-amitriptyline-treatment-on-neurofilament-h-protein-in-an-experimental-model-of-depression
#17
Maria Domenica Sanna, Carla Ghelardini, Nicoletta Galeotti
It has been proposed that depression is associated with dysfunction of hippocampal plasticity. Novel hypotheses suggest that antidepressants induce neuronal structural plasticity, although the underlying mechanisms still remain unclear. Therefore, the aim of this study was to investigate the effects of amitriptyline on levels of phosphorylated heavy neurofilament subunit (NF-H) in the hippocampus of mice exposed to acute and chronic behavioral despair paradigms. Immunoblotting experiments showed that animals exposed to the tail suspension test (TST) displayed diminished levels of pNF-H 24h after testing...
January 2017: Brain Research Bulletin
https://www.readbyqxmd.com/read/27781466/network-complement-transitions-symmetries-and-cluster-synchronization
#18
Takashi Nishikawa, Adilson E Motter
Synchronization in networks of coupled oscillators is known to be largely determined by the spectral and symmetry properties of the interaction network. Here, we leverage this relation to study a class of networks for which the threshold coupling strength for global synchronization is the lowest among all networks with the same number of nodes and links. These networks, defined as being uniform, complete, and multi-partite (UCM), appear at each of an infinite sequence of network-complement transitions in a larger class of networks characterized by having near-optimal thresholds for global synchronization...
September 2016: Chaos
https://www.readbyqxmd.com/read/27778048/optimality-and-stability-of-intentional-and-unintentional-actions-ii-motor-equivalence-and-structure-of-variance
#19
Behnoosh Parsa, Vladimir M Zatsiorsky, Mark L Latash
We address the nature of unintentional changes in performance in two papers. This second paper tested hypotheses related to stability of task-specific performance variables estimated using the framework of the uncontrolled manifold (UCM) hypothesis. Our first hypothesis was that selective stability of performance variables would be observed even when the magnitudes of those variables drifted unintentionally because of the lack of visual feedback. Our second hypothesis was that stability of a variable would depend on the number of explicit task constraints...
February 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/27756096/protective-effect-of-irbesartan-an-angiotensin-at1-receptor-antagonist-in-unpredictable-chronic-mild-stress-induced-depression-in-mice
#20
M Ayyub, A K Najmi, M Akhtar
Objective: Oxidative stress and alternation of renin-angiotensin system has been implicated in the pathophysiology of various cardio vascular, endocrine including mood and anxiety disorders. The present study evaluated the role of irbesartan in stress induced different models of depression. Materials and method: Mice were treated with irbesartan (40 mg/kg), fluoxetine (25 mg/kg) alone in combination orally. Drugs treatment started after 2 weeks from the beginning of the unpredictable mild stress (UCMS) protocol...
January 2017: Drug Research
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