keyword
https://read.qxmd.com/read/38441289/reduced-self-harm-on-acute-mental-health-wards-following-the-implementation-of-a-vision-based-patient-monitoring-system-evidence-from-five-nhs-trusts
#21
JOURNAL ARTICLE
Maria Kekic, Adam Rose, Cameron Baker, Daniel Bayley
WHAT IS KNOWN ON THE SUBJECT?: Inpatient mental health settings pose unique challenges for patient safety, in part because psychiatric disorders are well-known risk factors for self-harm and suicide. Ward staff follow protocols to try and keep patients safe including carrying out in-person safety checks, usually every 15 min, but patients unfortunately still find opportunities to harm themselves. A vision-based patient monitoring system (VBPMS) is a contact-free technology that can help mental health nurses to monitor patients in hospital more effectively...
March 5, 2024: Journal of Psychiatric and Mental Health Nursing
https://read.qxmd.com/read/38440198/experiences-barriers-and-expectations-regarding-current-patient-monitoring-systems-among-icu-nurses-in-a-university-hospital-in-lebanon-a-qualitative-study
#22
JOURNAL ARTICLE
Ahmad Rayan, Suhair H Al-Ghabeesh, Mirna Fawaz, Amal Behar, Amina Toumi
PURPOSE: The aim of the study is to assess the experiences, barriers, and expectations regarding current patient monitoring systems among intensive care unit nurses at one university hospital. METHODS: A qualitative exploratory study approach was adopted to test the research questions. RESULTS: Intensive care unit personnel placed a high value on practical criteria such as user friendliness and visualization while assessing the present monitoring system...
2024: Frontiers in digital health
https://read.qxmd.com/read/38438444/health-canada-advisory-impacts-on-the-prevalence-of-oral-codeine-use-in-the-pediatric-canadian-population-comparative-study-across-provinces
#23
JOURNAL ARTICLE
O Sheehy, S Eltonsy, S Hawken, M Walker, P Kaul, B Winquist, O Barrett, A Savu, R Dragan, M Pugliese, S Bernatsky, J Gorgui, A Bérard
Health Canada (HC) has, since 2013, issued safety alerts restricting the use of codeine-containing drugs among breastfeeding women and children/adolescents under 18 years of age. These products are linked to breathing problems among ultra-rapid CYP2D6 metabolizers and early use of opioid can lead to future opioid misuse. Using a multi-province population-based cohort study, we estimate the impact of federal safety alerts on annual rates of codeine use in the Canadian pediatric population. We analyzed data from 8,156,948 children/adolescents in five Canadian provinces between 1996 and 2021, using a common protocol...
March 4, 2024: Scientific Reports
https://read.qxmd.com/read/38431833/low-albumin-combined-with-low-molecular-weight-heparin-as-risk-factors-for-liver-injury-using-azvudine-evidence-from-an-analysis-of-covid-19-patients-in-a-national-prospective-pharmacovigilance-database
#24
JOURNAL ARTICLE
Hong Lu, Ying Zeng, Qun-Zhi Shi, Lin Liu, Yong-Qing Gong, Sen Li, Pan Yan
OBJECTIVE: Azvudine is an effective treatment for patients infected with common COVID-19. However, physicians have reported a series of adverse reactions, including multiple cases of liver injury, caused by azvudine in clinical practice. This study assessed the incidence, clinical features, and associated risk factors of liver injury induced by azvudine in real-world settings, offering guidance for safe clinical use. MATERIALS AND METHODS: This study utilized the Chinese Hospital Pharmacovigilance System (CHPS) to retrospectively analyze the treatment of COVID-19 patients with azvudine at Changsha Central Hospital from December 19, 2022, to June 6, 2023...
March 3, 2024: International Journal of Clinical Pharmacology and Therapeutics
https://read.qxmd.com/read/38429750/general-ward-nurses-detection-and-response-to-clinical-deterioration-in-three-hospitals-at-the-kenyan-coast-a-convergent-parallel-mixed-methods-study
#25
JOURNAL ARTICLE
Nickcy Mbuthia, Nancy Kagwanja, Moses Ngari, Mwanamvua Boga
BACKGROUND: In low and middle-income countries like Kenya, critical care facilities are limited, meaning acutely ill patients are managed in the general wards. Nurses in these wards are expected to detect and respond to patient deterioration to prevent cardiac arrest or death. This study examined nurses' vital signs documentation practices during clinical deterioration and explored factors influencing their ability to detect and respond to deterioration. METHODS: This convergent parallel mixed methods study was conducted in the general medical and surgical wards of three hospitals in Kenya's coastal region...
March 1, 2024: BMC Nursing
https://read.qxmd.com/read/38423993/safety-of-pre-hospital-peripheral-vasopressors-the-spotless-study-safety-of-prehospital-peripheral-vasopressors
#26
JOURNAL ARTICLE
Robbie Ley Greaves, Renee Bolot, Andrew Holgate, Clinton Gibbs
OBJECTIVE: To assess the safety and effectiveness of peripheral vasoactive drugs initiated during pre-hospital care and retrieval missions, in Queensland, Australia. METHODS: Three years of retrospective data was gathered from two sources. Medical notes were reviewed using a search for any patient having 'inotrope' recorded on an electronic medical record. Each case was reviewed to include only peripheral infusions of adrenaline or noradrenaline. Clinical Governance records were searched for adverse events related to vasoactive drugs, alerted for review to ensure complete capture...
February 29, 2024: Emergency Medicine Australasia: EMA
https://read.qxmd.com/read/38417230/the-effects-of-various-auditory-takeover-requests-a-simulated-driving-study-considering-the-modality-of-non-driving-related-tasks
#27
JOURNAL ARTICLE
Chunlei Chai, Yu Lei, Haoran Wei, Changxu Wu, Wei Zhang, Preben Hansen, Hao Fan, Jinlei Shi
With the era of automated driving approaching, designing an effective auditory takeover request (TOR) is critical to ensure automated driving safety. The present study investigated the effects of speech-based (speech and spearcon) and non-speech-based (earcon and auditory icon) TORs on takeover performance and subjective preferences. The potential impact of the non-driving-related task (NDRT) modality on auditory TORs was considered. Thirty-two participants were recruited in the present study and assigned to two groups, with one group performing the visual N-back task and another performing the auditory N-back task during automated driving...
February 27, 2024: Applied Ergonomics
https://read.qxmd.com/read/38407372/oral-intake-of-solid-medications-in-patients-with-post-stroke-dysphagia-a-challenge-for-nurses
#28
JOURNAL ARTICLE
Michaela Trapl-Grundschober, Steffen Schulz, Simon Sollereder, Lea Schneider, Yvonne Teuschl, Jürgen Osterbrink
AIM: To provide a comprehensive overview of how stroke nurses manage solid medication (SM) delivery to patients with post-stroke dysphagia. DESIGN: Cross-sectional study. METHODS: A self-administered online survey was carried out among nurses in German-speaking countries between September and December 2021. RESULTS: Out of a total of 754 responses, analysis was conducted on 195 nurses who reported working on a stroke unit...
February 26, 2024: Journal of Clinical Nursing
https://read.qxmd.com/read/38402518/let-s-settle-the-controversy-gelfoam-is-a-safe-intravascular-embolic-agent
#29
JOURNAL ARTICLE
Warren Clements, Matthew Lukies, Adil Zia, Mark Fitzgerald, Helen Kavnoudias
OBJECTIVES: A 2021 safety alert restricted endovascular gelfoam use in Australia and resulted in an embargo on gelfoam sales to IR departments. This study aimed to show that gelfoam is safe in a population of trauma patients with pelvic injury, and discuss the basis of the recent controversies. METHODS: Retrospective cohort study between 1 January 2010 and 21 May 2021 of patients who underwent gelfoam embolisation for pelvic arterial haemorrhage. Primary outcome was the rate of adverse events related to intravascular gelfoam administration...
February 24, 2024: British Journal of Radiology
https://read.qxmd.com/read/38402104/a-double-blind-randomised-four-way-crossover-study-to-compare-the-effects-of-fesoterodine-4-and-8-mg-once-daily-and-qxybutynin-5-mg-twice-daily-after-steady-state-dosing-versus-placebo-on-cognitive-function-in-overactive-bladder-wet-patients-over-the-age-of
#30
JOURNAL ARTICLE
Saima Rajabali, Prosper Asaana, Sahar Nazari, Adrian Wagg
BACKGROUND AND OBJECTIVE: There is a reported association between overactive bladder (OAB) treated with antimuscarinic drugs and an increased risk of a dementia diagnosis, although short-term data suggest that newer OAB antimuscarinics are cognitively safe. This study examined the cognitive safety of fesoterodine in older adults with mild cognitive impairment (MCI) and OAB. METHODS: This four-way randomised crossover study examined the cognitive effects of fesoterodine 4 and 8 mg and oxybutynin 5 mg b...
February 23, 2024: European Urology Focus
https://read.qxmd.com/read/38401243/modeling-the-influence-of-connected-vehicles-on-driving-behaviors-and-safety-outcomes-in-highway-crash-scenarios-across-varied-weather-conditions-a-multigroup-structural-equation-modeling-analysis-using-a-driving-simulator-experiment
#31
JOURNAL ARTICLE
Abdalziz Alruwaili, Kun Xie
Equipped with advanced sensors and capable of relaying safety messages to drivers, connected vehicles (CVs) hold the potential to reduce crashes. The goal of this study is to assess the impacts of CV technologies on driving behaviors and safety outcomes in highway crash scenarios under diverse weather conditions, including clear and foggy weather. A driving simulator experiment was conducted and the multigroup structural equation modeling (SEM) was employed to explore the complex interrelationships between the propensity of traffic conflicts, utilization of CV alerts, weather, psychological factors, driving behaviors, and other relevant variables for two different crash locations, namely a straight section and a horizontal curve...
February 23, 2024: Accident; Analysis and Prevention
https://read.qxmd.com/read/38400784/using-name-overlap-analysis-to-understand-medication-name-search-safety
#32
JOURNAL ARTICLE
Allen Flynn, Katherine D Mieure, Conor Myers
DISCLAIMER: In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time. PURPOSE: To examine the degree of left-to-right character overlap in medication names as they appear in real-world computer systems...
February 24, 2024: American Journal of Health-system Pharmacy: AJHP
https://read.qxmd.com/read/38400361/modulating-driver-alertness-via-ambient-olfactory-stimulation-a-wearable-electroencephalography-study
#33
JOURNAL ARTICLE
Mengting Jiang, Oranatt Chaichanasittikarn, Manuel Seet, Desmond Ng, Rahul Vyas, Gaurav Saini, Andrei Dragomir
Poor alertness levels and related changes in cognitive efficiency are common when performing monotonous tasks such as extended driving. Recent studies have investigated driver alertness decrement and possible strategies for modulating alertness with the goal of improving reaction times to safety critical events. However, most studies rely on subjective measures in assessing alertness changes, while the use of olfactory stimuli, which are known to be strong modulators of cognitive states, has not been commensurately explored in driving alertness settings...
February 12, 2024: Sensors
https://read.qxmd.com/read/38400338/an-iot-real-time-potable-water-quality-monitoring-and-prediction-model-based-on-cloud-computing-architecture
#34
JOURNAL ARTICLE
Rita Wiryasaputra, Chin-Yin Huang, Yu-Ju Lin, Chao-Tung Yang
In order to achieve the Sustainable Development Goals (SDG), it is imperative to ensure the safety of drinking water. The characteristics of each drinkable water, encompassing taste, aroma, and appearance, are unique. Inadequate water infrastructure and treatment can affect these features and may also threaten public health. This study utilizes the Internet of Things (IoT) in developing a monitoring system, particularly for water quality, to reduce the risk of contracting diseases. Water quality components data, such as water temperature, alkalinity or acidity, and contaminants, were obtained through a series of linked sensors...
February 11, 2024: Sensors
https://read.qxmd.com/read/38399588/why-do-we-not-wear-masks-anymore-during-the-covid-19-wave-vaccination-precludes-the-adoption-of-personal-non-pharmaceutical-interventions-a-quantitative-study-of-taiwanese-residents
#35
JOURNAL ARTICLE
Lee-Xieng Yang, Chia-Yuan Lin, Wan-Zhen Zhan, Bo-An Chiang, En-Chi Chang
Background and Objectives : This study examined whether the decline in people's adoption of personal NPIs (e.g., mask wearing) results from the preclusion by vaccination. This study also incorporates the concepts of risk perception and the risk-as-feelings model to elucidate the possible mechanisms behind this preclusion. Materials and Methods : Two cross-sectional surveys (N = 462 in Survey 1 and N = 505 in Survey 2) were administered before and during the first outbreak of COVID-19 in Taiwan. The survey items were designed to measure participants' perceived severity of COVID-19, worry about COVID-19, intention to adopt personal NPIs, and attitudes toward COVID-19 vaccines...
February 9, 2024: Medicina
https://read.qxmd.com/read/38395721/audiovestibular-adverse-events-following-covid-19-vaccinations
#36
JOURNAL ARTICLE
Aishwarya N Shetty, Hannah J Morgan, Linny K Phuong, John Mallard, Diana Vlasenko, Christopher Pearce, Nigel W Crawford, Jim P Buttery, Hazel J Clothier
INTRODUCTION: Evidence regarding audiovestibular adverse events post COVID-19 vaccination to date has been inconclusive regarding a potential association. This study aimed to determine if there was an increase in audiovestibular events following COVID-19 vaccination in South-eastern Australia during January 2021-March 2023. METHODS: A multi-data source approach was applied. First, a retrospective observational analysis of spontaneous reports of audiovestibular events to a statewide vaccine safety surveillance service, SAEFVIC...
February 22, 2024: Vaccine
https://read.qxmd.com/read/38393157/pyrrolizidine-alkaloids-in-foods-herbal-drugs-and-food-supplements-chemistry-metabolism-toxicological-significance-analytical-methods-occurrence-and-challenges-for-future
#37
REVIEW
Bruna Tábuas, Sílvia Cruz Barros, Catarina Diogo, Carlos Cavaleiro, Ana Sanches Silva
Consumers are increasingly seeking natural alternatives to chemical compounds, including the use of dried aromatic plants as seasonings instead of salt. However, the presence of pyrrolizidine alkaloids (PAs) in food supplements and dried plants has become a concern because of their link to liver diseases and their classification as carcinogenic by the International Agency for Research on Cancer (IARC). Despite European Union (EU) Regulation (EU) 2023/915, non-compliance issues persist, as indicated by alerts on the Rapid Alert System for Food and Feed (RASFF) portal...
February 2, 2024: Toxins
https://read.qxmd.com/read/38388881/prevalence-risk-factors-and-psychological-consequences-of-workplace-violence-among-health-workers-in-the-greater-accra-region-ghana-a-cross-sectional-study
#38
JOURNAL ARTICLE
Philip Apraku Tawiah, Emmanuel Appiah-Brempong, Paul Okyere, Geoffrey Adu-Fosu, Mary Eyram Ashinyo
BACKGROUND: Globally, close to one-third of all workplace violence (WV) occurs in the health sector. Exposure to WV among healthcare professionals in Ghana has been widely speculated, but there is limited evidence on the problem. This study therefore investigated WV, its risk factors, and the psychological consequences experienced by health workers in Ghana. METHODS: An analytic cross-sectional study was conducted in the Greater Accra region from January 30 to May 31, 2023, involving selected health facilities...
February 22, 2024: BMC Public Health
https://read.qxmd.com/read/38388174/pillharmonics%C3%A2-an-orchestrated-pharmacogenetics-medication-clinical-decision-support-service
#39
JOURNAL ARTICLE
Robert H Dolin, Edna C Shenvi, Carla Alvarez, Randolph Barrows, Aziz Boxwala, Benson Lee, Brian Nathanson, Yelena Kleyner, Rachel Hagemann, Tonya Hongsermeier, Joan Kapusnik-Uner, Adnan Lakdawala, James Shalaby
OBJECTIVES: Pharmacogenetics (PGx) is increasingly important in individualizing therapeutic management plans, but is often implemented apart from other types of medication clinical decision support (CDS). The lack of integration of pharmacogenetics into existing CDS may result in incomplete interaction information, which may pose patient safety concerns. We sought to develop a cloud-based orchestrated medication CDS service that integrates PGx with a broad set of drug screening alerts and evaluate it through a clinician utility study...
February 22, 2024: Applied Clinical Informatics
https://read.qxmd.com/read/38380652/-in-silico-prediction-of-chemical-acute-dermal-toxicity-using-explainable-machine-learning-methods
#40
JOURNAL ARTICLE
Shang Lou, Zhuohang Yu, Zejun Huang, Haoqiang Wang, Fei Pan, Weihua Li, Guixia Liu, Yun Tang
The research on acute dermal toxicity has consistently been a crucial component in assessing the potential risks of human exposure to active ingredients in pesticides and related plant protection products. However, it is difficult to directly identify the acute dermal toxicity of potential compounds through animal experiments alone. In our study, we separately integrated 1735 experimental data based on rabbits and 1679 experimental data based on rats to construct acute dermal toxicity prediction models using machine learning and deep learning algorithms...
February 21, 2024: Chemical Research in Toxicology
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