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https://www.readbyqxmd.com/read/29355439/design-and-clinical-evaluation-of-a-novel-low-glucose-prediction-algorithm-with-mini-dose-stable-glucagon-delivery-in-post-bariatric-hypoglycemia
#1
Alejandro J Laguna Sanz, Christopher M Mulla, Kristen M Fowler, Emilie Cloutier, Allison B Goldfine, Brett Newswanger, Martin Cummins, Sunil Deshpande, Steven J Prestrelski, Poul Strange, Howard Zisser, Francis J Doyle, Eyal Dassau, Mary-Elizabeth Patti
BACKGROUND: Postbariatric hypoglycemia (PBH) is a complication of bariatric surgery with limited therapeutic options. We developed an event-based system to predict and detect hypoglycemia based on continuous glucose monitor (CGM) data and recommend delivery of minidose liquid glucagon. METHODS: We performed an iterative development clinical study employing a novel glucagon delivery system: a Dexcom CGM connected to a Windows tablet running a hypoglycemia prediction algorithm and an Omnipod pump filled with an investigational stable liquid glucagon formulation...
February 2018: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/29351893/a-clinical-decision-support-engine-based-on-a-national-medication-repository-for-the-detection-of-potential-duplicate-medications-design-and-evaluation
#2
Cheng-Yi Yang, Yu-Sheng Lo, Ray-Jade Chen, Chien-Tsai Liu
BACKGROUND: A computerized physician order entry (CPOE) system combined with a clinical decision support system can reduce duplication of medications and thus adverse drug reactions. However, without infrastructure that supports patients' integrated medication history across health care facilities nationwide, duplication of medication can still occur. In Taiwan, the National Health Insurance Administration has implemented a national medication repository and Web-based query system known as the PharmaCloud, which allows physicians to access their patients' medication records prescribed by different health care facilities across Taiwan...
January 19, 2018: JMIR Medical Informatics
https://www.readbyqxmd.com/read/29324794/real-time-positioning-in-logging-effects-of-forest-stand-characteristics-topography-and-line-of-sight-obstructions-on-gnss-rf-transponder-accuracy-and-radio-signal-propagation
#3
Eloise G Zimbelman, Robert F Keefe
Real-time positioning on mobile devices using global navigation satellite system (GNSS) technology paired with radio frequency (RF) transmission (GNSS-RF) may help to improve safety on logging operations by increasing situational awareness. However, GNSS positional accuracy for ground workers in motion may be reduced by multipath error, satellite signal obstruction, or other factors. Radio propagation of GNSS locations may also be impacted due to line-of-sight (LOS) obstruction in remote, forested areas. The objective of this study was to characterize the effects of forest stand characteristics, topography, and other LOS obstructions on the GNSS accuracy and radio signal propagation quality of multiple Raveon Atlas PT GNSS-RF transponders functioning as a network in a range of forest conditions...
2018: PloS One
https://www.readbyqxmd.com/read/29324083/effects-of-napping-during-shift-work-on-sleepiness-and-performance-in-emergency-medical-services-personnel-and-similar-shift-workers-a-systematic-review-and-meta-analysis
#4
Christian Martin-Gill, Laura K Barger, Charity G Moore, J Stephen Higgins, Ellen M Teasley, Patricia M Weiss, Joseph P Condle, Katharyn L Flickinger, Patrick J Coppler, Denisse J Sequeira, Ayushi A Divecha, Margaret E Matthews, Eddy S Lang, P Daniel Patterson
BACKGROUND: Scheduled napping during work shifts may be an effective way to mitigate fatigue-related risk. This study aimed to critically review and synthesize existing literature on the impact of scheduled naps on fatigue-related outcomes for EMS personnel and similar shift worker groups. METHODS: A systematic literature review was performed of the impact of a scheduled nap during shift work on EMS personnel or similar shift workers. The primary (critical) outcome of interest was EMS personnel safety...
January 11, 2018: Prehospital Emergency Care
https://www.readbyqxmd.com/read/29323437/parenteral-nutrition-safety-the-story-continues
#5
REVIEW
Phil Ayers, Joseph Boullata, Gordon Sacks
Parenteral nutrition (PN) is an important therapeutic modality used for a variety of indications in adults, children, and infants. PN is a complex, high-alert medication that requires appropriate education and ongoing competency assessment to ensure a safe process. PN is not recognized by many organizations as a medication, which leads to underreporting of errors. This article will provide important insight and recommendations to promote a safe PN process.
January 11, 2018: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/29319338/vigilance-and-sentinels-in-global-health-security
#6
Chris Lyttleton
Global health security is increasingly reliant on vigilance to provide early warning of transnational health threats. In theory, this approach requires that sentinels, based in communities most affected by new or re-emerging infectious diseases, deliver timely alerts of incipient risk. Medicalizing global safety also implies there are particular forms of insecurity that must be remedied to pre-empt disease spread. I examine vigilance in the context of spreading drug resistant malaria in Southeast Asian border zones and argue that to act as sentinels, marginal groups vulnerable to infection must be able to articulate what social and behavioral factors prompt proliferating disease risks...
January 10, 2018: Medical Anthropology
https://www.readbyqxmd.com/read/29301226/impact-of-pharmacist-conducted-comprehensive-medication-reviews-for-older-adult-patients-to-reduce-medication-related-problems
#7
Whitney J Kiel, Shaun W Phillips
Older adults are demanding increased healthcare attention with regards to prescription use due in large part to highly complex medication regimens. As patients age, medications often have a more pronounced effect on older adults, negatively impacting patient safety and increasing healthcare costs. Comprehensive medication reviews (CMRs) optimize medications for elderly patients and help to avoid inappropriate medication use. Previous literature has shown that such CMRs can successfully identify and reduce the number of medication-related problems and improve acute healthcare utilization...
December 31, 2017: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/29297761/an-improved-model-to-predict-performance-under-mental-fatigue
#8
Henry T Peng, Fethi Bouak, Wenbi Wang, Renee Chow, Oshin Vartanian
Fatigue has become an increasing problem in our modern society. Using MATLAB as a generic modelling tool, a fatigue model was developed based on an existing one and compared with a commercial fatigue software for prediction of cognitive performance under total and partial sleep deprivation. The flexibility of our fatigue model allowed additions of new algorithms and mechanisms for non-sleep factors and countermeasures and thus improved model predictions and usability for both civilian and military applications...
January 8, 2018: Ergonomics
https://www.readbyqxmd.com/read/29288903/environmental-and-human-health-risk-indicators-for-agricultural-pesticides-in-estuaries
#9
Elsa Teresa Rodrigues, Maria Fátima Alpendurada, Fernando Ramos, Miguel Ângelo Pardal
The present study aims to contribute to a better assessment of pesticide environmental and human health (here evaluated in the context of human exposure via food items) risks for the estuarine system by comprehensively studying the spatial and temporal occurrence of the pesticides atrazine, azoxystrobin, bentazon, λ-cyhalothrin, penoxsulam and terbuthylazine in the River Mondego estuary (Portugal). Pesticide quantification was performed in surface water, sediment, macroalgae (Ulva spp., Gracilaria gracilis, Fucus vesiculosus), aquatic plants (Zostera noltii, Spartina maritime, Scirpus maritimus) and bivalves (Scrobicularia plana)...
December 27, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29277384/effectiveness-of-visual-warnings-on-young-drivers-hazard-anticipation-and-hazard-mitigation-abilities
#10
Foroogh Hajiseyedjavadi, Tingru Zhang, Ravi Agrawal, Michael Knodler, Donald Fisher, Siby Samuel
Previous studies have demonstrated that young drivers fail both to scan for and mitigate latent hazards mostly due to their cluelessness. This study aims to investigate whether these skills could be improved by providing young drivers with alerts in advance of the upcoming threat using a driving simulator experiment. In particular, the warning was presented on the head-up displays (HUD) either 2 s, 3 s or 4 s in advance of a latent threat. The hazard anticipation, hazard mitigation and attention maintenance performance of forty-eight young drivers aged 18-25 was evaluated across eight unique scenarios either in the presence or in the absence of latent threat alerts displayed on a HUD...
December 22, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29239662/the-effect-of-electronic-health-records-on-patient-safety-a-qualitative-exploratory-study
#11
Ahmad Tubaishat
BACKGROUND: Electronic health records (EHRs) are increasingly used in healthcare settings and it is believed that they have brought benefits to patients and healthcare services alike. Few previous studies, however, have explored the impact of these records on patient safety. AIM: The overall purpose of this study was to explore the effect of EHRs on patient safety, as perceived by nurses. METHODS: This qualitative exploratory study was conducted using semi-structured interviews with staff nurses working in hospitals that employed the same EHR system in Jordan...
December 14, 2017: Informatics for Health & Social Care
https://www.readbyqxmd.com/read/29232260/high-alert-medication-stratification-tool-revised-an-exploratory-study-of-an-objective-standardized-medication-safety-tool
#12
Natalie C Washburn, Heather A Dossett, Andrew C Fritschle, Kerri E Degenkolb, Monica R Macik, Todd A Walroth
OBJECTIVE: To develop an objective tool designed to standardize the identification of high-alert medications (HAMs) according to patient safety risk. METHODS: Medications were evaluated using the High-Alert Medication Stratification Tool (HAMST). Tool revision occurred through assessing medications on an organization-approved HAM list and comparing scores with control medications not included on the list. Because of variations in HAMST interpretation by end users in interdisciplinary committees, a revision of the scoring tool was completed to create the High-Alert Medication Stratification Tool-Revised (HAMST-R), and the assessment was repeated...
December 12, 2017: Journal of Patient Safety
https://www.readbyqxmd.com/read/29218304/from-invention-to-innovation-risk-analysis-to-integrate-one-health-technology-in-the-dairy-farm
#13
Andrea Lombardo, Carlo Boselli, Simonetta Amatiste, Simone Ninci, Chiara Frazzoli, Roberto Dragone, Alberto De Rossi, Gerardo Grasso, Alberto Mantovani, Giovanni Brajon
Current Hazard Analysis Critical Control Points (HACCP) approaches mainly fit for food industry, while their application in primary food production is still rudimentary. The European food safety framework calls for science-based support to the primary producers' mandate for legal, scientific, and ethical responsibility in food supply. The multidisciplinary and interdisciplinary project ALERT pivots on the development of the technological invention (BEST platform) and application of its measurable (bio)markers-as well as scientific advances in risk analysis-at strategic points of the milk chain for time and cost-effective early identification of unwanted and/or unexpected events of both microbiological and toxicological nature...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/29212486/emerging-concepts-and-spectrum-of-renal-injury-following-intravesical-bcg-for-non-muscle-invasive-bladder-cancer
#14
Azharuddin Mohammed, Zubair Arastu
BACKGROUND: Intravesical Bacilli Calmette-Guerin (IVBCG) therapy for non-muscle invasive bladder cancer (NMIBC) has long been in use successfully. Albeit rarely, we still face with its safety concerns more than 25 years on since its approval by US Food and Drug Agency in 1990. Local and systemic infection following intravesical BCG is widely reported as compared to immune mediated local or systemic hypersensitivity reactions involving kidneys; acute kidney injury (AKI) and other renal manifestations are well reported but not of chronic kidney disease (CKD)...
December 6, 2017: BMC Urology
https://www.readbyqxmd.com/read/29210766/tele-icu-and-patient-safety-considerations
#15
Erkan Hassan
The tele-ICU is designed to leverage, not replace, the need for bedside clinical expertise in the diagnosis, treatment, and assessment of various critical illnesses. Tele-ICUs are primarily decentralized or centralized models with differing advantages and disadvantages. The centralized model has sufficiently powered published data to be associated with improved mortality and ICU length of stay in a cost-effective manner. Factors associated with improved clinical outcomes include improved compliance with best practices; providing off-hours implementation of the bedside physician's care plan; and identification of and rapid response to physiological instability (initial clinical review within 1 hour) and rapid response to alerts, alarms, or direct notification by bedside clinicians...
January 2018: Critical Care Nursing Quarterly
https://www.readbyqxmd.com/read/29207564/obstacle-detection-as-a-safety-alert-in-augmented-reality-models-by-the-use-of-deep-learning-techniques
#16
Dawid Połap, Karolina Kęsik, Kamil Książek, Marcin Woźniak
Augmented reality (AR) is becoming increasingly popular due to its numerous applications. This is especially evident in games, medicine, education, and other areas that support our everyday activities. Moreover, this kind of computer system not only improves our vision and our perception of the world that surrounds us, but also adds additional elements, modifies existing ones, and gives additional guidance. In this article, we focus on interpreting a reality-based real-time environment evaluation for informing the user about impending obstacles...
December 4, 2017: Sensors
https://www.readbyqxmd.com/read/29203458/evaluating-in-car-movements-in-the-design-of-mindful-commute-interventions-exploratory-study
#17
Pablo Enrique Paredes, Nur Al-Huda Hamdan, Dav Clark, Carrie Cai, Wendy Ju, James A Landay
BACKGROUND: The daily commute could be a right moment to teach drivers to use movement or breath towards improving their mental health. Long commutes, the relevance of transitioning from home to work, and vice versa and the privacy of commuting by car make the commute an ideal scenario and time to perform mindful exercises safely. Whereas driving safety is paramount, mindful exercises might help commuters decrease their daily stress while staying alert. Increasing vehicle automation may present new opportunities but also new challenges...
December 4, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29203025/demographic-determinants-of-chemical-safety-information-recall-in-workers-and-consumers-in-south-africa-a-cross-sectional-study
#18
Farzana Sathar, Mohamed Aqiel Dalvie, Hanna-Andrea Rother, Leslie London
BACKGROUND: Chemical hazard communication is intended to alert users of the potential hazards of chemicals. Hazard information needs to be understood and recalled. Recall of hazard communication is critical when the written form of the information is not available at the time it is required. METHODS: A cross-sectional study investigating associations between recall of chemical safety information on labels amongst 402 participants including 315 workers and 87 consumers in two provinces of South Africa...
December 2017: Journal of Safety Research
https://www.readbyqxmd.com/read/29202907/challenges-and-path-forward-on-mandatory-allergen-labeling-and-voluntary-precautionary-allergen-labeling-for-a-global-company
#19
Jupiter Yeung, Marie-Claude Robert
For food manufacturers, the label on a food package is a tool meant to alert consumers to the presence of specific allergens, allowing consumers to make informed decisions and not unnecessarily limit their food choices. Mandatory allergen labeling is used when the allergen is an intentionally added ingredient, whereas voluntary allergen labeling is used when the presence of the allergen is unintentional and may be in the finished product as a result of cross-contact. In a globalized economy, ensuring food safety is a growing challenge for manufacturers...
December 5, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/29202489/-physician-pharmacist-communication-about-potentially-severe-drug-interactions
#20
Alexandra Pulst, Isabel Justus, Guido Schmiemann
Introduction Potentially serious drug interactions are often detected by pharmacists. In such cases fast communication with the General Practitioner (GP) is required. However, contacting physicians by telephone is often difficult. In a previous project a fax template was developed allowing fast communication of serious drug interactions to the GP. Utilization of the template and interactions detected were assessed in this observational study. Methods All pharmacists and GP in the city of Bremen were informed about the template...
December 4, 2017: Deutsche Medizinische Wochenschrift
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