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https://www.readbyqxmd.com/read/27915361/neuroscience-literacy-brain-tells-as-signals-of-brain-dysfunction-affecting-daily-life
#1
Charlotte B Royeen, James R Brašić, Leah Dvorak, Casey Provoziak-O'Brien, Chetna Sethi, S Omar Ahmad
The structures and circuits of the central and the peripheral nervous systems provide the basis for thinking, speaking, experiencing sensations, and performing perceptual and motor activities in daily life. Healthy people experience normal functioning without giving brain functions a second thought, while dysfunction of the neural circuits may lead to marked impairments in cognition, communication, sensory awareness, and performing perceptual and motor tasks. Neuroscience literacy provides the knowledge to associate the deficits observed in patients with the underlying deficits in the structures and circuits of the nervous system...
2016: Journal of Allied Health
https://www.readbyqxmd.com/read/27908833/pilot-evaluation-of-a-method-to-assess-prescribers-information-processing-of-medication-alerts
#2
Alissa L Russ, Brittany L Melton, Joanne K Daggy, Jason J Saleem
BACKGROUND: Prescribers commonly receive alerts during medication ordering. Prescribers work in a complex, time-pressured environment; to enhance the effectiveness of safety alerts, the effort needed to cognitively process these alerts should be minimized. Methods to evaluate the extent to which computerized alerts support prescribers' information processing are lacking. OBJECTIVE: To develop a methodological protocol to assess the extent to which alerts support prescribers' information processing at-a-glance; specifically, the incorporation of information into working memory...
November 28, 2016: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/27904631/the-effect-of-clinical-supervision-model-on-high-alert-medication-safety-in-intensive-care-units-nurses
#3
Asghar Khalifehzadeh Esfahani, Fatemeh Ramezany Varzaneh, Tahereh Changiz
BACKGROUND: Medication errors and adverse drug events of high alert medication are one of the major problems in therapeutic system. The purpose of the present study was to investigate ύthe effect of clinical supervision model on high alert medication safety in intensive care units nurses. MATERIALS AND METHODS: This was a quasi-experimental study conducted on 32 nurses of intensive care units. The researcher observed the administration of high alert drugs including heparin, warfarin, norepinephrine, dobutamine, and dopamine by nurses and recorded the scores of the work in preventing medication errors, the work in preventing adverse drug events, and medication safety...
September 2016: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/27896144/clinical-decision-support-for-drug-related-events-moving-towards-better-prevention
#4
REVIEW
Sandra L Kane-Gill, Archita Achanta, John A Kellum, Steven M Handler
Clinical decision support (CDS) systems with automated alerts integrated into electronic medical records demonstrate efficacy for detecting medication errors (ME) and adverse drug events (ADEs). Critically ill patients are at increased risk for ME, ADEs and serious negative outcomes related to these events. Capitalizing on CDS to detect ME and prevent adverse drug related events has the potential to improve patient outcomes. The key to an effective medication safety surveillance system incorporating CDS is advancing the signals for alerts by using trajectory analyses to predict clinical events, instead of waiting for these events to occur...
November 4, 2016: World Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/27872407/fatigue-work-schedules-and-perceived-performance-in-bedside-care-nurses
#5
Knar Sagherian, Michael E Clinton, Huda Abu-Saad Huijer, Jeanne Geiger-Brown
Hospital nurses are expected to maintain optimal work performance; yet, fatigue can threaten safe practice and result in unfavorable patient outcomes. This descriptive cross-sectional study explored the association between fatigue, work schedules, and perceived work performance among nurses. The study sample included 77 bedside nurses who were mostly female, single, and between 20 and 29 years of age. The majority worked 8-hour shifts and overtime. Nurses who worked during off days reported significantly higher chronic fatigue compared with those nurses who took time off...
November 21, 2016: Workplace Health & Safety
https://www.readbyqxmd.com/read/27871098/traffic-accidents-involving-cyclists-identifying-causal-factors-using-questionnaire-survey-traffic-accident-data-and-real-world-observation
#6
Shoko Oikawa, Toshiya Hirose, Shigeru Aomura, Yasuhiro Matsui
The purpose of this study is to clarify the mechanism of traffic accidents involving cyclists. The focus is on the characteristics of cyclist accidents and scenarios, because the number of traffic accidents involving cyclists in Tokyo is the highest in Japan. First, dangerous situations in traffic incidents were investigated by collecting data from 304 cyclists in one city in Tokyo using a questionnaire survey. The survey indicated that cyclists used their bicycles generally while commuting to work or school in the morning...
November 2016: Stapp Car Crash Journal
https://www.readbyqxmd.com/read/27862933/patterns-in-response-to-chronic-terrorism-threats-a-construct-of-emotional-cognitive-and-behavioral-responses-among-israeli-citizens
#7
Keren Cohen-Louck, Yael Saka
Israeli citizens are exposed to unpredictable and chronic terrorism threats that significantly jeopardize their personal sense of safety. The purpose of the present study is to present how Israeli discourse is structured with regard to emotional, cognitive, and behavioral responses to chronic terrorism threats and to understand the range of responses as well as map the risk and protective factors of this existential threat. Semistructured in-depth interviews were conducted with 40 Israeli adults (22 women and 18 men)...
November 10, 2016: Stress and Health: Journal of the International Society for the Investigation of Stress
https://www.readbyqxmd.com/read/27859873/impact-of-an-intervention-on-the-prescription-of-aliskiren-after-new-evidence-on-safety-reported
#8
Isabel Rosich Martí, Alejandro Allepuz, Gemma Rodriguez Palomar, Francesca Ortin Font, Maria Soler Cera
PURPOSE: The purpose of the study is to analyze the impact of an intervention to disseminate safety alerts on the utilization of Aliskiren added to angiotensin converting enzyme inhibitor (ACEI) or an angiotensin-receptor blocker (ARB). METHODS: Quasi-experimental design (non-randomized intervention) comparing the utilization of Aliskiren + ACEI or ARB in a primary care area-intervention (PCA-I) with a primary care area-control (PCA-C) following a safety alert...
November 16, 2016: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/27851710/a-community-hospital-s-evaluation-of-alarm-management-safety-factors
#9
Emma Kurnat-Thoma, Kayuri Shah
BACKGROUND: The Joint Commission's 2014 National Patient Safety Goals required hospitals to evaluate alarm safety in 2014-2015 and implement alarm safety policies. OBJECTIVE: The aim of this study was to assess common alarm management safety factors in our 187-bed community hospital. METHODS: Two weeks' worth of IV pump report data was evaluated to characterize 33 IV pump alarm types. Hospital and IV pump noise was measured, and an alarm management nurse survey was conducted...
December 2016: Journal of Nursing Administration
https://www.readbyqxmd.com/read/27835722/effects-of-adjunctive-brexpiprazole-on-sleep-disturbances-in-patients-with-major-depressive-disorder-an-open-label-flexible-dose-exploratory-study
#10
Andrew D Krystal, Aurélia Mittoux, Peter Meisels, Ross A Baker
Background: Brexpiprazole is a serotonin-dopamine activity modulator. We evaluated the effects of adjunctive treatment with brexpiprazole on sleep disturbances in patients with DSM-IV-TR major depressive disorder (MDD) and inadequate response to antidepressant treatment. Methods: This study was conducted between September 27, 2013, and August 19, 2014. Patients with inadequate response to antidepressant treatment and sleep disturbances continued treatment with their current antidepressant for 2 weeks...
September 8, 2016: Primary Care Companion to CNS Disorders
https://www.readbyqxmd.com/read/27834964/a-review-of-145%C3%A2-234-ophthalmic-patient-episodes-lost-to-follow-up
#11
A Davis, A Baldwin, M Hingorani, A Dwyer, D Flanagan
PurposeLost to follow-up and delays in follow-up care are a major problem in chronic diseases, particularly when irreversible progression precedes symptoms. The NPSA Glaucoma Safety Alert in 2009 highlighted the risk and requirements for consistent robust review systems in ophthalmology. In response, Moorfields Eye Hospital reviewed the records of all patients in all subspecialties without review appointments booked. The purpose of this study was to determine whether ophthalmic patients lost to follow-up had come to harm and develop investigation techniques to optimise safety, which do not put excessive demands on clinical staff time...
November 11, 2016: Eye
https://www.readbyqxmd.com/read/27830233/health-informatics-in-developing-countries-a-review-of-unintended-consequences-of-it-implementations-as-they-affect-patient-safety-and-recommendations-on-how-to-address-them
#12
C Otero, A A Almerares, D Luna, A Marcelo, M Househ, H Mandirola
BACKGROUND: Patient safety concerns every healthcare organization. Adoption of Health information technology (HIT) appears to have the potential to address this issue, however unanticipated and undesirable consequences from implementing HIT could lead to new and more complex hazards. This could be particularly problematic in developing countries, where regulations, policies and implementations are few, less standandarized and in some cases almost non-existing. METHODS: Based on the available information and our own experience, we conducted a review of unintended consequences of HIT implementations, as they affect patient safety in developing countries...
November 10, 2016: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/27826189/behavioral-emergency-in-the-elderly-a-descriptive-study-of-patients-referred-to-an-aggression-response-team-in-an-acute-hospital
#13
Daniel Simpkins, Carmelle Peisah, Irene Boyatzis
AIM: The management of severely agitated elderly patients is not easy, and limited guidelines are available to assist practitioners. At a Sydney hospital, an Aggression Response Team (ART) comprising clinical and security staff can be alerted when a staff member has safety concerns. Our aims were to describe the patient population referred for ART calls, reasons for and interventions during ART calls, and complications following them. METHODS: Patients 65 years and older referred for ART calls in the emergency department or wards during 2014 were identified using the Incident Information Management System database and medical records were reviewed...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27826016/attention-and-driving-performance-modulations-due-to-anger-state-contribution-of-electroencephalographic-data
#14
Franck Techer, Christophe Jallais, Yves Corson, Fabien Moreau, Daniel Ndiaye, Bruno Piechnick, Alexandra Fort
Driver internal state, including emotion, can have negative impacts on road safety. Studies have shown that an anger state can provoke aggressive behavior and impair driving performance. Apart from driving, anger can also influence attentional processing and increase the benefits taken from auditory alerts. However, to our knowledge, no prior event-related potentials study assesses this impact on attention during simulated driving. Therefore, the aim of this study was to investigate the impact of anger on attentional processing and its consequences on driving performance...
November 4, 2016: Neuroscience Letters
https://www.readbyqxmd.com/read/27808392/retraction-retraction-of-efficacy-and-safety-of-nucleoside-analogues-in-preventing-vertical-transmission-of-the-hepatitis-b-virus-from-father-to-infant-by-l-h-cao-p-l-zhao-z-m-liu-s-c-sun-d-b-xu-j-d-zhang-and-z-h-shao-genet-mol-res-14-4-15539-15546-2015
#15
L-H Cao, P-L Zhao, Z-M Liu, S-C Sun, D-B Xu, J-D Zhang, Z-H Shao
The retracted article is: Cao L-H, Zhao P-L, Liu Z-M, Sun S-C, et al. (2015). Efficacy and safety of nucleoside analogues in preventing vertical transmission of the hepatitis B virus from father to infant. Genet. Mol. Res. 14: 15539-15546. The article published in Genetics and Molecular Research 14 (4): 15539-15546 (2015) is a very good paper, but it appears that the authors' group submitted this manuscript to multiple journals, which is ethical misconduct. This manuscript (similar language and identical data) was published in the Experimental and Therapeutic Medicine Journal prior to being submitted to GMR...
October 7, 2016: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/27804174/monitoring-safety-in-a-phase-iii-real-world-effectiveness-trial-use-of-novel-methodology-in-the-salford-lung-study
#16
Sue Collier, Catherine Harvey, Jill Brewster, Nawar Diar Bakerly, Hanaa F Elkhenini, Roxana Stanciu, Claire Williams, Jacqui Brereton, John P New, John McCrae, Sheila McCorkindale, David Leather
BACKGROUND: The Salford Lung Study (SLS) programme, encompassing two phase III pragmatic randomised controlled trials, was designed to generate evidence on the effectiveness of a once-daily treatment for asthma and chronic obstructive pulmonary disease in routine primary care using electronic health records. OBJECTIVE: The objective of this study was to describe and discuss the safety monitoring methodology and the challenges associated with ensuring patient safety in the SLS...
November 1, 2016: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/27799149/dtb-select-11-november-2016
#17
(no author information available yet)
Impact of hepatic enzyme-inducing drugs on levonorgestrel EHC ● New clinical rule to improve antibiotic prescribing to children ● The impact of nursery sickness policies on the treatment of conjunctivitis ● Patient safety alert for acute kidney injury ● Do strategies to reduce polypharmacy improve patient-relevant outcomes? ● When is a health app a medical device? ● Automated feedback reduces high-risk prescribing in primary care ● Quantifying resting heart rate as a predictor of disease.
October 31, 2016: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/27787363/the-safety-and-efficacy-of-alfentanil-based-induction-in-bronchoscopy-sedation-a-randomized-double-blind-controlled-trial
#18
Chung-Hsing Hsieh, Ting-Yu Lin, Tsai-Yu Wang, Chih-Hsi Kuo, Shu-Min Lin, Han-Pin Kuo, Yu-Lun Lo
BACKGROUND: Alfentanil in combination with propofol produces a synergistic sedative effect in patients undergoing flexible bronchoscopy (FB). However, the use of this combination is controversial due to the risk of cardiopulmonary depression. The aim of this study was to evaluate the proper induction regimen of alfentanil in propofol target-controlled infusion for FB sedation. METHODS: One hundred seventy-three patients were assigned randomly into 5 regimens: Group 1 and 2, alfentanil 2...
October 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27786335/how-physician-perspectives-on-e-prescribing-evolve-over-time-a-case-study-following-the-transition-between-ehrs-in-an-outpatient-clinic
#19
Erika L Abramson, Vaishali Patel, Elizabeth R Pfoh, Rainu Kaushal
BACKGROUND: Physicians are expending tremendous resources transitioning to new electronic health records (EHRs), with electronic prescribing as a key functionality of most systems. Physician dissatisfaction post-transition can be quite marked, especially initially. However, little is known about how physicians' experiences using new EHRs for e-prescribing evolve over time. We previously published a qualitative case study about the early physician experience transitioning from an older to a newer, more robust EHR, in the outpatient setting, focusing on their perceptions of the electronic prescribing functionality...
October 26, 2016: Applied Clinical Informatics
https://www.readbyqxmd.com/read/27784751/switching-from-inadequate-adjunctive-or-combination-treatment-options-to-brexpiprazole-adjunctive-to-antidepressant-an-open-label-study-on-the-effects-on-depressive-symptoms-and-cognitive-and-physical-functioning
#20
Maurizio Fava, Takao Okame, Yuki Matsushima, Pamela Perry, Emmanuelle Weiller, Ross A Baker
BACKGROUND: Approximately 50% of patients with major depressive disorder (MDD) do not respond adequately to their antidepressant treatment (ADT), underscoring the need for more effective treatment options. The objective of this study was to investigate the effect of adjunctive brexpiprazole on depressive symptoms in patients with MDD who were not responding to adjunctive or combination therapy of their current ADTs with several different classes of agents (NCT02012218). METHODS: In this 6-week, open-label, phase 3b study, patients with MDD who had an inadequate response to ≥1 adjunctive or combination therapy, in addition to history of ≥1 failure to monotherapy ADT, were switched to adjunctive brexpiprazole...
October 26, 2016: International Journal of Neuropsychopharmacology
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