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https://www.readbyqxmd.com/read/29679621/the-global-burden-of-hyperglycemia-in-pregnancy-trends-from-studies-in-the-last-decade
#1
REVIEW
Bhuvan Martin, David A Sacks
Concurrent with the rise in obesity, global rates of diabetes are increasing at alarming rates in both developed and developing nations. As these conditions become more prevalent among women of reproductive age, rates of hyperglycemia in pregnancy (HIP) are also increasing. HIP is associated with many immediate perinatal complications which affect both maternal and fetal/neonatal health, as well as with more long term complications. Long term complications include an increase in chronic non-communicable diseases in both mother and offspring, therefore affecting future generations...
April 18, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29678978/community-based-diagnosis-of-non-communicable-diseases-and-their-risk-factors-in-rural-and-urban-haiti-a-cross-sectional-prevalence-study
#2
Vincent DeGennaro, Stuart Malcolm, Lindsay Crompton, Krishna Vaddiparti, Lazarus K Mramba, Catherine Striley, Linda Cottler, Kellee Taylor, Robert Leverence
OBJECTIVE: To estimate the prevalence of hypertension, diabetes and chronic kidney disease and their risk factors in a rural and urban region of Haiti. SETTING AND PARTICIPANTS: Community health workers enumerated 2648 households (909 rural and 1739 urban) via a multistage cluster random sampling method from July 2015 to May 2016, completed 705 rural and 1419 urban assessments for adults aged 25-65 years. OUTCOME MEASURES: We performed a WHO STEPS based questionnaire, measured two blood pressure values, weight, height, abdominal circumference and point of care test finger stick blood sample for haemoglobin A1c, creatinine and cholesterol (total, high density lipoprotein (HDL) and triglycerides)...
April 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29678896/outcomes-for-patients-with-rheumatic-heart-disease-after-cardiac-surgery-followed-at-rural-district-hospitals-in-rwanda
#3
Emmanuel K Rusingiza, Ziad El-Khatib, Bethany Hedt-Gauthier, Gedeon Ngoga, Symaque Dusabeyezu, Neo Tapela, Cadet Mutumbira, Francis Mutabazi, Emmanuel Harelimana, Joseph Mucumbitsi, Gene F Kwan, Gene Bukhman
BACKGROUND: In sub-Saharan Africa, continued clinical follow-up, after cardiac surgery, is only available at urban referral centres. We implemented a decentralised, integrated care model to provide longitudinal care for patients with advanced rheumatic heart disease (RHD) at district hospitals in rural Rwanda before and after heart surgery. METHODS: We collected data from charts at non-communicable disease (NCD) clinics at three rural district hospitals in Rwanda to describe the outcomes of 54 patients with RHD who received cardiac valve surgery during 2007-2015...
April 20, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29678607/association-between-hypertension-and-metabolic-disorders-among-elderly-patients-in-north-jordan
#4
Nuha Alwardat, Laura Di Renzo, Renata Costa de Miranda, Sofian Alwardat, Paola Sinibaldi Salimei, Antonino De Lorenzo
BACKGROUND: Hypertension (HTN), dyslipidemia and hyperglycemia are major risk factors for cardiovascular disease, accounting for the highest morbidity and mortality among the elderly Jordanian population. This study aimed to evaluate serum lipid and glucose profiles of hypertensive patients and normotensive controls, and determine the risk factors for HTN among elderly population in Jordan. METHODS: A cross-sectional study was carried out among 200 participants, including 111 hypertensive patients and 89 normotensive controls from June to October 2017 in North Jordan...
April 12, 2018: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29678180/emerging-role-of-exosome-derived-long-non-coding-rnas-in-tumor-microenvironment
#5
REVIEW
Zhenqiang Sun, Shuaixi Yang, Quanbo Zhou, Guixian Wang, Junmin Song, Zhen Li, Zhiyong Zhang, Jizhong Xu, Kunkun Xia, Yuan Chang, Jinbo Liu, Weitang Yuan
Exosomes are extracellular vesicles released by many cell types and have been attributed for their roles in many diseases including cancer. Exosomes secreted by tumor cells and stromal cells are critical mediators of intercellular communication in tumor microenvironments. Long noncoding RNAs (lncRNAs) are selectively sorted into exosomes and can regulate cancer onset and progression in a variety of ways. In this review, we summarize the characteristics of exosomal lncRNAs and their dysregulation in multiple types of cancer...
April 20, 2018: Molecular Cancer
https://www.readbyqxmd.com/read/29678160/the-increasing-burden-and-complexity-of-multi-morbidity-and-polypharmacy-in-geriatric-hiv-patients-a-cross-sectional-study-of-people-aged-65-74-years-and-more-than-75-years
#6
G Guaraldi, A Malagoli, A Calcagno, C Mussi, B M Celesia, F Carli, S Piconi, G V De Socio, A M Cattelan, G Orofino, A Riva, E Focà, S Nozza, G Di Perri
BACKGROUND: Geriatric Patients Living with HIV/AIDS (GEPPO) is a new prospective observational multicentre cohort consisting of all the HIV-positive geriatric patients being treated at 10 clinics in Italy, and HIV-negative controls attending a single geriatric clinic. The aim of this analysis of the GEPPO cohort was to compare prevalence and risk factors of individual non-communicable diseases (NCD), multi-morbidity (MM) and polypharmacy (PP) amongst HIV positive and HIV negative controls at enrolment into the GEPPO cohort...
April 20, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29678132/neck-circumference-may-be-a-valuable-tool-for-screening-individuals-with-obesity-findings-from-a-young-chinese-population-and-a-meta-analysis
#7
Xiaoting Pei, Li Liu, Mustapha Umar Imam, Ming Lu, Yanzi Chen, Panpan Sun, Yaxin Guo, Yiping Xu, Zhiguang Ping, Xiaoli Fu
BACKGROUND: Central obesity and overweight/obesity can result in various chronic non-communicable diseases, such as cardiovascular disease, metabolic syndrome, and diabetes mellitus. Waist circumference (WC) and body mass index (BMI) are widely used to measure obesity despite their limitations. For example, WC and BMI cannot be measured in pregnant women and subjects with abdominal ascites or masses. Therefore, this study aims to determine the efficacy of neck circumference (NC) as a tool for screening central obesity and overweight/obesity...
April 20, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29677219/the-association-of-adult-height-with-the-risk-of-cardiovascular-disease-and-cancer-in-the-population-of-sardinia
#8
Giovanni Mario Pes, Antonello Ganau, Eugenia Tognotti, Alessandra Errigo, Chiara Rocchi, Maria Pina Dore
The relationship between body height and the risk of non‒communicable diseases such as cardiovascular disease and cancer has been the subject of much debate in the epidemiological literature. Concerns have recently arisen over spurious associations due to confounding factors like birth cohort, especially in the context of epidemiological transition. The population of Sardinia represents an interesting case study, as the average physical stature of inhabitants was the lowest recorded in Europe until a few decades ago...
2018: PloS One
https://www.readbyqxmd.com/read/29674487/metals-in-urine-in-relation-to-the-prevalence-of-pre-diabetes-diabetes-and-atherosclerosis-in-rural-india
#9
Ganesan Velmurugan, Krishnan Swaminathan, Ganesh Veerasekar, Jonathan Q Purnell, Sundaresan Mohanraj, Mani Dhivakar, Anil Kumar Avula, Mathew Cherian, Nalla G Palaniswami, Thomas Alexander, Thalappil Pradeep
OBJECTIVE: Diabetes and cardiovascular diseases are growing burdens in rural communities worldwide. We have observed a high prevalence of diabetes among rural farming communities in India and sought to evaluate the association of non-traditional risk factors, such as metals, with diabetes and other cardiometabolic risk factors in this community. METHODS: Anthropometric measurements, chemistries and carotid intima-media thickness were determined in 865 participants of the Kovai Medical Center and Hospital-Nallampatti Non-Communicable Disease Study-I (KMCH-NNCD-I, 2015), a cross-sectional study conducted in a farming village in South India...
April 19, 2018: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29674364/health-and-prevention-enhancement-h-peace-a-retrospective-population-based-cohort-study-conducted-at-the-seoul-national-university-hospital-gangnam-center-korea
#10
Changhyun Lee, Eun Kyung Choe, Ji Min Choi, Yunji Hwang, Young Lee, Boram Park, Su Jin Chung, Min-Sun Kwak, Jong-Eun Lee, Joo Sung Kim, Sue Kyung Park, Sang-Heon Cho
PURPOSE: The Health and Prevention Enhancement (H-PEACE) study was designed to investigate the association of diagnostic imaging results, biomarkers and the predisease stage of non-communicable diseases (NCDs), such as malignancies and metabolic diseases, in an average-risk population in Korea. PARTICIPANTS: This study enrolled a large-scale retrospective cohort at the Healthcare System Gangnam Center, Seoul National University Hospital, from October 2003 to December 2014...
April 19, 2018: BMJ Open
https://www.readbyqxmd.com/read/29673873/before-the-beginning-nutrition-and-lifestyle-in-the-preconception-period-and-its-importance-for-future-health
#11
REVIEW
Judith Stephenson, Nicola Heslehurst, Jennifer Hall, Danielle A J M Schoenaker, Jayne Hutchinson, Janet E Cade, Lucilla Poston, Geraldine Barrett, Sarah R Crozier, Mary Barker, Kalyanaraman Kumaran, Chittaranjan S Yajnik, Janis Baird, Gita D Mishra
A woman who is healthy at the time of conception is more likely to have a successful pregnancy and a healthy child. We reviewed published evidence and present new data from low-income, middle-income, and high-income countries on the timing and importance of preconception health for subsequent maternal and child health. We describe the extent to which pregnancy is planned, and whether planning is linked to preconception health behaviours. Observational studies show strong links between health before pregnancy and maternal and child health outcomes, with consequences that can extend across generations, but awareness of these links is not widespread...
April 16, 2018: Lancet
https://www.readbyqxmd.com/read/29673375/stages-of-behavioural-change-after-direct-to-consumer-disease-risk-profiling-study-protocol-of-two-integrated-controlled-pragmatic-trials
#12
Kelly F J Stewart, Anke Wesselius, Annemie M W J Schols, Maurice P Zeegers
BACKGROUND: The incidence and prevalence of chronic diseases have reached epidemic proportions during the last decades and are not expected to diminish. Chronic diseases increasingly affect younger individuals too, with over 40% of all deaths due to non-communicable diseases occurring before the age of 70. This has led to the development of information services aimed at preventive health care, such as Health Potential®. This counselling service estimates a personal disease risk of a carefully selected list of preventable common chronic diseases that have both a genetic and a lifestyle component of development...
April 19, 2018: Trials
https://www.readbyqxmd.com/read/29673041/the-causes-of-maternal-mortality-are-changing-and-preventable
#13
Mary J Stokes, Jeffrey P Wilkinson
McCaw-Binns' identified trends in maternal and late maternal mortality in Jamaica which mirror trends seen elsewhere. The WHO reported in 2016 that non-communicable diseases (NCD) were the leading cause of death for women (comprising 65% of deaths), with over 75% of these deaths occurring in low and middle-income countries (LMIC). (World Health Organization and UNICEF (2016) A systematic analysis of global causes of maternal deaths from 2003-2009 found one-quarter were due to indirect causes - primarily NCDs including heart disease, stroke, cancer, and chronic respiratory disease...
April 19, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29671872/cerebral-palsy-non-communicable-diseases-and-lifespan-care
#14
Kevin P Murphy
No abstract text is available yet for this article.
April 19, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/29669396/discordance-between-population-impact-of-musculoskeletal-disorders-and-scientific-interest-a-bibliometric-study
#15
Anthony V Perruccio, Calvin Yip, J Denise Power, Mayilee Canizares, Elizabeth M Badley
OBJECTIVE: Musculoskeletal disorders (MSDs) are a leading cause of healthy years lost due to premature mortality and disability. Our objective was to investigate whether MSDs were commensurably represented within the published health literature. METHODS: MEDLINE bibliometric data were retrieved for 2016 and 2011. The 25 disease branches, including MSDs, were ranked according to published paper counts, proportion of all publications, and increase in publications from 2011 to 2016...
April 18, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29666210/regulation-and-mechanisms-of-extracellular-vesicle-biogenesis-and-secretion
#16
REVIEW
Crislyn D'Souza-Schorey, Jeffrey S Schorey
EV (extracellular vesicle) biology is a rapidly expanding field. These heterogeneous membrane vesicles, which are shed from virtually all cell types, collectively represent a new dimension of intercellular communication in normal physiology and disease. They have been shown to deliver infectious and pathogenic agents to non-infected cells whereas in cancers they are thought to condition the tumor microenvironment. Their presence in body fluids and inherent capacity for systemic delivery point to their clinical promise...
April 17, 2018: Essays in Biochemistry
https://www.readbyqxmd.com/read/29664035/out-of-pocket-expenditure-for-hospitalization-in-haryana-state-of-india-extent-determinants-financial-risk-protection
#17
Deepshikha Sharma, Shankar Prinja, Arun Kumar Aggarwal, Pankaj Bahuguna, Atul Sharma, Saroj Kumar Rana
Background & objectives: India aspires to achieve universal health coverage, which requires ensuring financial risk protection (FRP). This study was done to assess the extent of out-of-pocket (OOP) expenditure and FRP for hospitalization in Haryana State, India. Further, the determinants for FRP were also evaluated. Methods: Data collected as a part of a household level survey conducted in Haryana 'Concurrent Evaluation of National Rural Health Mission: Haryana Health Survey' were analyzed...
December 2017: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29663859/factors-contributing-to-and-strategies-to-combat-emerging-arboviruses
#18
David Michael Callender
Less than half a century ago infectious diseases appeared to be destined to be extinguished via as a culmination of medical triumphs. As focus turned towards combating non-communicable diseases, emerging and re-emerging diseases (EIDs) have bloomed from those ashes. Five epidemic mosquito-borne arboviruses (Yellow Fever virus (YFV), Dengue virus, West Nile virus, Chikungunya virus, and Zika virus) have emerged in the recent past. Arboviruses are of the utmost importance with respect to EIDs due to intensive growth of globalisation, arthropod urban fitness/adaption, and environmental changes...
April 17, 2018: Global Public Health
https://www.readbyqxmd.com/read/29662045/macronutrient-and-major-food-group-intake-in-a-cohort-of-southern-italian-adults
#19
Serena Mulè, Mariagiovanna Falla, Alessandra Conti, Dora Castiglione, Isabella Blanco, Armando Platania, Maurizio D'Urso, Marina Marranzano
BACKGROUND: Dietary intake of macronutrient and foods is considered crucial to decrease the risk of diet-related non-communicable diseases. METHODS: The aim of this study was to describe the intake of major food groups and macronutrients in a random sample of 1838 southern Italian adults. RESULTS: No significant differences of macronutrient consumption between sexes were found. By contrast, younger individuals had significantly higher intake of animal protein than older ones...
April 15, 2018: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/29661995/greater-glycaemic-response-to-an-oral-glucose-load-in-healthy-lean-active-and-young-chinese-adults-compared-to-matched-caucasians
#20
Trevor Simper, Caroline Dalton, David Broom, Waleed Ibrahim, Lingjin Li, Charles Bankole, Sisi Chen
There are ethnic differences recorded in glycaemic response and rates of type 2 diabetes mellitus (DM) between Chinese and Caucasian populations. Whether these differences are evident in matched healthy, lean, active, young adults is unclear. This study compares the postprandial glycaemic response of a group of Chinese participants ( n = 49) with a group of similar Caucasians, ( n = 48) aged 23.8 (±4.35 years), body mass index (BMI) 22.7 (±2.6) kg/m², healthy (free from non-communicable disease), and lean (body fat % 23...
April 14, 2018: Nutrients
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