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Value based pricing

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https://www.readbyqxmd.com/read/29337604/the-current-status-of-outcomes-based-contracting-for-manufacturers-and-payers-an-amcp-membership-survey
#1
Amy Duhig, Soumi Saha, Stacie Smith, Stew Kaufman, Janet Hughes
BACKGROUND: As the United States health care system shifts from traditional volume-based payments to value-based payments, outcomes-based contracts (OBCs) are gaining popularity among payers and manufacturers as a mechanism for the shift toward value. Under this model, stakeholders hope to align drug payment and value to real-world performance metrics (e.g., biomarkers and health care resource utilization). OBJECTIVE: To understand the experiences, perceptions, and needs of payers and manufacturers related to OBCs...
December 22, 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/29316935/estimating-the-returns-to-united-kingdom-publicly-funded-musculoskeletal-disease-research-in-terms-of-net-value-of-improved-health-outcomes
#2
Matthew Glover, Erin Montague, Alexandra Pollitt, Susan Guthrie, Stephen Hanney, Martin Buxton, Jonathan Grant
BACKGROUND: Building on an approach applied to cardiovascular and cancer research, we estimated the economic returns from United Kingdom public- and charitable-funded musculoskeletal disease (MSD) research that arise from the net value of the improved health outcomes in the United Kingdom. METHODS: To calculate the economic returns from MSD-related research in the United Kingdom, we estimated (1) the public and charitable expenditure on MSD-related research in the United Kingdom between 1970 and 2013; (2) the net monetary benefit (NMB), derived from the health benefit in quality adjusted life years (QALYs) valued in monetary terms (using a base-case value of a QALY of £25,000) minus the cost of delivering that benefit, for a prioritised list of interventions from 1994 to 2013; (3) the proportion of NMB attributable to United Kingdom research; and (4) the elapsed time between research funding and health gain...
January 10, 2018: Health Research Policy and Systems
https://www.readbyqxmd.com/read/29313250/adolescents-perceptions-of-the-economy-its-association-with-academic-engagement-and-the-role-of-school-based-and-parental-relationships
#3
Nancy E Hill, Belle Liang, Diamond Y Bravo, Maggi Price, Whitney Polk, John Perella, Mandy Savitz-Romer
In the context of widespread media coverage of economic problems, un- and under-employment, and overwhelming student loan debt, youth are making sense of the prospects of getting a job and value of education. Further, they are assessing the implications of the job market in curtailing or enhancing their future success. School-based and familial relationships may support students in making sense of the job market. The current study focuses on how youth view the economy, its association with academic engagement, and how parental and school-based relationships shape views of the job market and their impact on academic engagement...
January 8, 2018: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/29298337/evaluating-the-influential-priority-of-the-factors-on-insurance-loss-of-public-transit
#4
Wenhui Zhang, Yongmin Su, Ruimin Ke, Xinqiang Chen
Understanding correlation between influential factors and insurance losses is beneficial for insurers to accurately price and modify the bonus-malus system. Although there have been a certain number of achievements in insurance losses and claims modeling, limited efforts focus on exploring the relative role of accidents characteristics in insurance losses. The primary objective of this study is to evaluate the influential priority of transit accidents attributes, such as the time, location and type of accidents...
2018: PloS One
https://www.readbyqxmd.com/read/29297049/cost-effectiveness-of-the-adjuvanted-herpes-zoster-subunit-vaccine-in-older-adults
#5
Phuc Le, Michael B Rothberg
Importance: The live attenuated herpes zoster vaccine (ZVL) is recommended for immunocompetent adults 60 years or older, but the efficacy wanes with age and over time. A new adjuvanted herpes zoster subunit vaccine (HZ/su) has higher efficacy but might be more expensive. The choice of vaccines depends on their relative values. Objective: To assess the cost-effectiveness of HZ/su. Design, Setting, and Participants: Markov decision model with transition probabilities based on the US medical literature...
January 2, 2018: JAMA Internal Medicine
https://www.readbyqxmd.com/read/29278823/the-relationship-between-cross-sectional-shapes-and-ftir-profiles-in-synthetic-wig-fibers-and-their-discriminating-abilities-an-evidential-value-perspective
#6
Theresa A Joslin Yogi, Michael Penrod, Melinda Holt, Patrick Buzzini
Wig fragments or fibers may occasionally be recognized as potential physical evidence during criminal investigations. While analytical methods traditionally adopted for the examination of textile fibers are utilized for the characterizations and comparisons of wig specimens, it is essential to understand in deeper detail the valuable contribution of features of these non-routine evidentiary materials as well as the relationship of the gathered analytical data. This study explores the dependence between the microscopic features of cross-sectional shapes and the polymer type gathered by Fourier transform infrared (FTIR) spectroscopy...
December 15, 2017: Forensic Science International
https://www.readbyqxmd.com/read/29274520/managing-imperfect-competition-by-pay-for-performance-and-reference-pricing
#7
Henry Y Mak
I study a managed health service market where differentiated providers compete for consumers by choosing multiple service qualities, and where copayments that consumers pay and payments that providers receive for services are set by a payer. The optimal regulation scheme is two-sided. On the demand side, it justifies and clarifies value-based reference pricing. On the supply side, it prescribes pay for performance when consumers misperceive service benefits or providers have intrinsic quality incentives. The optimal bonuses are expressed in terms of demand elasticities, service technology, and provider characteristics...
November 5, 2017: Journal of Health Economics
https://www.readbyqxmd.com/read/29261699/sugary-drinks-taxation-projected-consumption-and-fiscal-revenues-in-colombia-evidence-from-a-quaids-model
#8
Juan Carlos Caro, Shu Wen Ng, Ricardo Bonilla, Jorge Tovar, Barry M Popkin
The global shift towards diets high in sugar-sweetened beverages (SSBs) is linked to higher prevalence of obesity, diabetes and most other non-communicable diseases. In Colombia, one out of every two people was overweight or obese by 2010. This study estimates price-elasticities from a Quadratic Almost Ideal Demand System model, using the 2006-2007 Colombian Income and Expenditure survey. The food groups that were jointly considered were: unsweetened unflavored milks; coffee and tea; sugar sweetened beverages (SSBs); sweets and candies (including sugar); dairy products; meats and animal-based products; grains based staples; fruits and vegetables; and condiments and snacks...
2017: PloS One
https://www.readbyqxmd.com/read/29261249/real-world-economic-value-of-a-21-gene-assay-in-early-stage-breast-cancer
#9
Stanley E Waintraub, Donna McNamara, Deena Mary Atieh Graham, Andrew L Pecora, John Min, Tommy Wu, Hyun Gi Noh, Jacqueline Connors, Ruth Pe Benito, Kelly Choi, Eric Schultz, Stuart L Goldberg
OBJECTIVES: Value-based payment reforms shift cost-containment responsibilities to the physician. Although gene expression profiling (GEP) utilizing a 21-gene panel among patients with early-stage, axillary lymph node-negative, hormone receptor-positive, HER2/neu oncogene-negative breast cancer is able to identify a cohort that may achieve excellent outcomes without adjuvant chemotherapy, high up-front costs (list price, $4175) could dissuade usage. STUDY DESIGN: Retrospective review of consecutive patients with breast cancer treated at a single cancer center...
December 1, 2017: American Journal of Managed Care
https://www.readbyqxmd.com/read/29248864/examination-of-approach-and-avoidance-inclinations-on-the-reinforcing-value-of-alcohol
#10
Emily T Noyes, Robert C Schlauch
Although behavioral economics tends to focus on environmental factors (i.e., price, availability) that act to influence valuation of alcohol, recent research has begun to address how motivational and cognitive factors influence an individual's demand for alcohol. Motivational states, including craving, are one possible mechanism underlying the value based decision making that demand represents. Using a multidimensional model of craving (Ambivalence Model of Craving), the current study examined the relationships between indices of alcohol demand (i...
December 6, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/29247179/iron-based-nanocatalyst-for-the-acceptorless-dehydrogenation-reactions
#11
Garima Jaiswal, Vinod G Landge, Dinesh Jagadeesan, Ekambaram Balaraman
Development of sustainable catalytic systems for fundamentally important synthetic transformations and energy storage applications is an intellectually stimulating challenge. Catalytic dehydrogenation of feedstock chemicals, such as alcohols and amines to value-added products with the concomitant generation of dihydrogen is of much interest in the context of hydrogen economy and is an effective alternative to the classical oxidation reactions. Despite a number of homogeneous catalysts being identified for the acceptorless dehydrogenation, the use of high price and limited availability of precious metals and poor recovery of the catalyst have spurred interest in catalysis with more earth-abundant alternatives, especially iron...
December 15, 2017: Nature Communications
https://www.readbyqxmd.com/read/29246917/acist-ffr-study-assessment-of-catheter-based-interrogation-and-standard-techniques-for-fractional-flow-reserve-measurement
#12
William F Fearon, Jeffrey W Chambers, Arnold H Seto, Ian J Sarembock, Ganesh Raveendran, Charlotte Sakarovitch, Lingyao Yang, Manisha Desai, Allen Jeremias, Matthew J Price
BACKGROUND: Measurement of fractional flow reserve (FFR) to guide coronary revascularization lags despite robust supportive data, partly because of the handling characteristics of traditional coronary pressure wires. An optical pressure-monitoring microcatheter, which can be advanced over a traditional coronary guidewire, facilitates FFR assessment but may underestimate pressure wire-derived FFR. METHODS AND RESULTS: In this prospective, multicenter trial, 169 patients underwent FFR assessment with a pressure wire alone and with a pressure microcatheter over the pressure wire...
December 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29242977/the-mechanism-in-junctional-failure-of-thoraco-lumbar-fusions-part-i-biomechanical-analysis-of-mechanisms-responsible-of-vertebral-overstress-and-description-of-the-cervical-inclination-angle-cia
#13
Jean-Charles Le Huec, Jonathon Richards, Andreas Tsoupras, Rachel Price, Amélie Léglise, Antonio A Faundez
PURPOSE: The purpose of the study is to describe the biomechanical theory explaining junctional breakdowns in thoraco-lumbar fusions, by taking the example of vertebral compression fractures. Also, a new angle, the cervical inclination angle (CIA), describing the relative position of the head at each vertebral level, is presented. METHODS: For the CIA, the data were collected from 137 asymptomatic subjects of a prospective database, containing clinical and radiologic informations...
December 14, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29238027/viscous-flow-behaviour-of-karanja-oil-based-biolubricant-base-oil
#14
Umesh Chandra Sharma, Sadhana Sachan, Rakesh Kumar Trivedi
Karanja oil (KO) is widely used for synthesis of bio-fuel karanja oil methyl ester (KOME) due to its competitive price, good energy values and environmentally friendly combustion properties. Bio-lubricant is another value added product that can be synthesized from KO via chemical modification. In this work karanja oil trimethylolpropane ester (KOTMPE) bio-lubricant was synthesized and evaluated for its viscous flow behaviour. A comparison of viscous flow behaviours of natural KO and synthesized bio-fuel KOME and bio-lubricant KOTMPE was also made...
December 14, 2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/29228339/thresholds-for-decision-making-informing-the-cost-effectiveness-and-affordability-of-rotavirus-vaccines-in-malaysia
#15
Tharani Loganathan, Chiu-Wan Ng, Way-Seah Lee, Raymond C W Hutubessy, Stéphane Verguet, Mark Jit
Cost-effectiveness thresholds (CETs) based on the Commission on Macroeconomics and Health (CMH) are extensively used in low- and middle-income countries (LMICs) lacking locally defined CETs. These thresholds were originally intended for global and regional prioritization, and do not reflect local context or affordability at the national level, so their value for informing resource allocation decisions has been questioned. Using these thresholds, rotavirus vaccines are widely regarded as cost-effective interventions in LMICs...
December 8, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/29228154/comparative-transcriptomic-analysis-of-human-placentae-at-term-and-preterm-delivery
#16
Alison G Paquette, Heather M Brockway, Nathan D Price, Louis J Muglia
Purpose: Preterm birth affects 1 out of every 10 infants in the United States, resulting in substantial neonatal morbidity and mortality. Currently, there are few predictive markers and few treatment options to prevent preterm birth. A healthy, functioning placenta is essential to positive pregnancy outcomes. Previous studies have suggested that placental pathology may play a role in preterm birth etiology. Therefore, we tested the hypothesis that preterm placentae may exhibit unique transcriptomic signatures compared to term samples reflective of their abnormal biology leading to this adverse outcome...
December 4, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/29223847/funding-breakthrough-therapies-a-systematic-review-and-recommendation
#17
REVIEW
E Hanna, M Toumi, C Dussart, B Borissov, O Dabbous, K Badora, P Auquier
BACKGROUND: Advanced therapy medicinal products (ATMPs) are innovative therapies likely associated with high prices. Payers need guidance to create a balance between ensuring patient access to breakthrough therapies and maintaining the financial sustainability of the healthcare system. OBJECTIVE: The aims of this study were to identify, define, classify and compare the approaches to funding high-cost medicines proposed in the literature, to analyze their appropriateness for ATMP funding and to suggest an optimal funding model for ATMPs...
December 2, 2017: Health Policy
https://www.readbyqxmd.com/read/29223766/developing-a-value-proposition-for-high-sensitive-troponin-testing
#18
Andrew St John, Louise Cullen, Paul Jülicher, Christopher P Price
Laboratories are looking for ways that they can identify and deliver value through their service rather than just provide high quality test results. One way to demonstrate value has been described in the form of a value proposition where the application of a laboratory test is described explicitly in terms of the process of care and the patient outcomes. We have applied this concept to the use of high sensitive troponin assays for the assessment of patients with suspected acute coronary syndrome. From a previously described framework we use a checklist to describe the various steps in the complete intervention or clinical pathway, demonstrating how the test should be used, highlighting key evidence in the literature that supports the intervention and list some of the measures which can be used to assess how well the intervention is being adopted and implemented...
December 6, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29218306/adolescents-responses-to-a-school-based-prevention-program-promoting-healthy-eating-at-school
#19
Roel C J Hermans, Hanneke de Bruin, Junilla K Larsen, Fréderike Mensink, Annet C Hoek
Background: To improve the effectiveness of school-based programs that aim to promote adolescents' healthy food choices, it is essential to understand the views and behaviors of the target group. This study aimed to get a better understanding of adolescents' food and health perceptions and their willingness to be involved in a specific school-based prevention program, i.e., the Dutch "Healthy School Canteen Program." Methods: This study used a mixed-methods research design...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/29212509/incremental-cost-and-cost-effectiveness-of-low-dose-high-frequency-training-in-basic-emergency-obstetric-and-newborn-care-as-compared-to-status-quo-part-of-a-cluster-randomized-training-intervention-evaluation-in-ghana
#20
Michelle Willcox, Heather Harrison, Amos Asiedu, Allyson Nelson, Patricia Gomez, Amnesty LeFevre
BACKGROUND: Low-dose, high-frequency (LDHF) training is a new approach best practices to improve clinical knowledge, build and retain competency, and transfer skills into practice after training. LDHF training in Ghana is an opportunity to build health workforce capacity in critical areas of maternal and newborn health and translate improved capacity into better health outcomes. METHODS: This study examined the costs of an LDHF training approach for basic emergency obstetric and newborn care and calculates the incremental cost-effectiveness of the LDHF training program for health outcomes of newborn survival, compared to the status quo alternative of no training...
December 6, 2017: Globalization and Health
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