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Value based pricing

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https://www.readbyqxmd.com/read/29147089/multiple-regression-analysis-to-estimate-the-unit-price-of-hanwoo-bos-taurus-coreanae-beef
#1
Seung-Hoon Eum, Hu-Rak Park, Jakyeom Seo, Seong-Keun Cho, Sun-Jin Hur, Byeong-Woo Kim
This study were estimated the contribution of carcass traits to unit price, to analyze the marbling score as a categorical variable rather than a numerical variable, and to develop an optimal model that also includes the holiday effect and the raising period. The data for this study were acquired from the Quality Evaluation of the Korea Institute for Animal Products, and consisted of the trading records of 1,613,699 heads at 12 wholesale markets from 2010 to 2014. The unit price of a cow was estimated from the following parameters: -52...
2017: Korean Journal for Food Science of Animal Resources
https://www.readbyqxmd.com/read/29143620/optimising-diagnosis-of-viraemic-hepatitis-c-infection-the-development-of-a-target-product-profile
#2
Elena Ivanova Reipold, Philippa Easterbrook, Alessandra Trianni, Nivedha Panneer, Douglas Krakower, Stefano Ongarello, Teri Roberts, Veronica Miller, Claudia Denkinger
BACKGROUND: The current low access to virological testing to confirm chronic viraemic HCV infection in low- and middle-income countries (LMIC) is limiting the rollout of hepatitis C (HCV) care. Existing tests are complex, costly and require sophisticated laboratory infrastructure. Diagnostic manufacturers need guidance on the optimal characteristics a virological test needs to have to ensure the greatest impact on HCV diagnosis and treatment in LMIC. Our objective was to develop a target product profile (TPP) for diagnosis of HCV viraemia using a global stakeholder consensus-based approach...
November 1, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29136172/assessing-the-contraceptive-supply-environment-in-kinshasa-drc-trend-data-from-pma2020
#3
S Babazadeh, S Lea, P Kayembe, P Akilimali, L Eitmann, P Anglewicz, J Bertrand
Performance Monitoring and Accountability 2020 (PMA2020) is a population-based and facility-based survey program conducted in 11 countries to track contraceptive use dynamics and the supply environment. Annual data collection provides trend data unavailable from any other source. Two-stage cluster sampling was used to select 58 enumeration areas in Kinshasa; data were collected in 2014, 2015 and 2016 from three to six service delivery points (SDPs) per EA. Of the 228-248 SDPs surveyed each year, only two-thirds reported to offer family planning (FP) services...
November 10, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/29135615/diffusion-of-bevacizumab-across-oncology-practices-an-observational-study
#4
Nancy L Keating, Haiden A Huskamp, Deborah Schrag, John M McWilliams, Barbara J McNeil, Bruce E Landon, Michael E Chernew, Sharon-Lise T Normand
BACKGROUND: Technological advances can improve care and outcomes but are a primary driver of health care spending growth. Understanding diffusion and use of new oncology therapies is important, given substantial increases in prices and spending on such treatments. OBJECTIVES: Examine diffusion of bevacizumab, a novel (in 2004) and high-priced biologic cancer therapy, among US oncology practices during 2005-2012 and assess variation in use across practices. RESEARCH DESIGN: Population-based observational study...
November 10, 2017: Medical Care
https://www.readbyqxmd.com/read/29115686/inner-volume-echo-volumar-imaging-ivevi-for-robust-fetal-brain-imaging
#5
Rita G Nunes, Giulio Ferrazzi, Anthony N Price, Jana Hutter, Andreia S Gaspar, Mary A Rutherford, Joseph V Hajnal
PURPOSE: Fetal functional MRI studies using conventional 2-dimensional single-shot echo-planar imaging sequences may require discarding a large data fraction as a result of fetal and maternal motion. Increasing the temporal resolution using echo volumar imaging (EVI) could provide an effective alternative strategy. Echo volumar imaging was combined with inner volume (IV) imaging (IVEVI) to locally excite the fetal brain and acquire full 3-dimensional images, fast enough to freeze most fetal head motion...
November 8, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29083973/amcp-partnership-forum-advancing-value-based-contracting
#6
(no author information available yet)
During the past decade, payment models for the delivery of health care have undergone a dramatic shift from focusing on volume to focusing on value. This shift began with the Affordable Care Act and was reinforced by the Medicare Access and CHIP Reauthorization Act of 2015 (MACRA), which increased the emphasis on payment for delivery of quality care. Today, value-based care is a primary strategy for improving patient care while managing costs. This shift in payment models is expanding beyond the delivery of health care services to encompass models of compensation between payers and biopharmaceutical manufacturers...
November 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/29070761/price-adjustment-for-traditional-chinese-medicine-procedures-based-on-a-standardized-value-parity-model
#7
Haiyin Wang, Chunlin Jin, Qingwu Jiang
Traditional Chinese medicine (TCM) is an important part of China's medical system. Due to the prolonged low price of TCM procedures and the lack of an effective mechanism for dynamic price adjustment, the development of TCM has markedly lagged behind Western medicine. The World Health Organization (WHO) has emphasized the need to enhance the development of alternative and traditional medicine when creating national health care systems. The establishment of scientific and appropriate mechanisms to adjust the price of medical procedures in TCM is crucial to promoting the development of TCM...
October 24, 2017: Bioscience Trends
https://www.readbyqxmd.com/read/29056375/the-economic-impact-of-agricultural-pollutions-in-iran-spatial-distance-function-approach
#8
Hamed Najafi Alamdarlo
Pollution has increased in Iran in the last two decades due to agricultural activities. Pollutions are released into the atmosphere and thereafter pollute water and soil resources. Therefore, it is important to develop models that can estimate the economic value of these Pollutions. For this purpose, a Spatial Output Distance Function was used in the present study to estimate the shadow price of carbon dioxide emission and water salinity in spatial and temporal dimensions. This method can be used as a new method to estimate the value of externalities...
October 19, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29052259/molecular-switches-for-any-ph-a-systematic-study-of-the-versatile-coordination-behaviour-of-cyclam-scorpionands
#9
Yu Heng Lau, Jack K Clegg, Jason R Price, Rene B Marquart, Matthew H Todd, Peter J Rutledge
Molecular switches have many potential applications in nanoscience and biomedicine. Transition metal complexes that can be switched from an unreactive state to an active one by a simple change in conditions (e.g. pH shift) or by binding to a specific biomolecular target - so-called target-activated metal complexes (TAMCs) - hold particular allure as a means of harnessing the potent but at times indiscriminate reactivity of metal-based drugs. We have prepared a series of ten structurally related ligands each of which bears a different pendant side-arm functional group off a common macrocyclic core...
October 19, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29036734/benefit-cost-analysis-of-radiocesium-decorporation-by-a-prussian-blue-treatment-and-stockpiling
#10
Alexis Rump, Daniela Stricklin, Andreas Lamkowski, Stefan Eder, Matthias Port
In the case of an attack by a "dirty bomb" with cesium-137 there is a risk of internal contamination. The excretion of cesium-137 can be enhanced by Prussian Blue (PB), and thus the committed effective dose be reduced. We analyzed the benefit and costs of PB decorporation treatment. We simulated the reduction of the radiological dose by PB treatment after cesium-137 incorporation by inhalation. The saving of life time was quantified using the monetary "value of a statistical life" (VSL). Treatment costs were based on the market price of PB in Germany...
October 16, 2017: Drug Research
https://www.readbyqxmd.com/read/29032722/comparison-of-fermented-animal-feed-and-mushroom-growth-media-as-two-value-added-options-for-waste-cassava-pulp-management
#11
Sivalee Trakulvichean, Pawinee Chaiprasert, Julia Otmakhova, Warinthorn Songkasiri
Cassava is one of the main processed crops in Thailand, but this generates large amounts (7.3 million tons in 2015) of waste cassava pulp (WCP). The solid WCP is sold directly to farmers or pulp-drying companies at a low cost to reduce the burden of on-site waste storage. Using an integrated direct and environmental cost model, fermented animal feed and mushroom growth media were compared as added-value waste management alternatives for WCP to mitigate environmental problems. Primary and secondary data were collected from the literature, field data, and case studies...
October 1, 2017: Waste Management & Research
https://www.readbyqxmd.com/read/29028656/costs-and-benefits-of-on-demand-hiv-pre-exposure-prophylaxis-in-men-who-have-sex-with-men-analysis-of-the-anrs-ipergay-study-with-a-one-year-follow-up
#12
Isabelle Durand-Zaleski, Pierre Mutuon, Isabelle Charreau, Cecile Tremblay, Daniela Rojas, Gilles Pialoux, Christian Chidiac, Catherine Capitant, Bruno Spire, Laurent Cotte, Julie Chas, Laurence Meyer
OBJECTIVES: We undertook the economic evaluation of the double-blind randomized ANRS-IPERGAY trial which showed the efficacy of on-demand pre-exposure prophylaxis (PrEP) with tenofovir-disoproxil-fumarate (TDF-FTC) in preventing HIV infection among high risk men-who have-sex-with-men (MSM). DESIGN & METHODS: The economic evaluation was prospective. Counseling, drugs (TDF-FTC at &OV0556;500.88 for 30 tablets), tests, visits and hospital admissions were valued based on in-trial use...
October 12, 2017: AIDS
https://www.readbyqxmd.com/read/29021380/cost-effectiveness-of-nivolumab-in-recurrent-metastatic-head-and-neck-squamous-cell-carcinoma
#13
Mahdi Zargar, Thomas McFarlane, Kelvin K W Chan, William W L Wong
BACKGROUND: Treatment options for patients with platinum-refractory, recurrent, metastatic head and neck squamous cell carcinoma (r/m HNSCC) are limited and prognosis is poor. The recent CheckMate 141 clinical trial demonstrated that nivolumab, an anti-programmed cell death protein 1 monoclonal antibody, was efficacious in extending the median overall survival (OS) in this patient population compared with standard therapies. We conducted a cost-effectiveness analysis to determine whether nivolumab is a cost-effective treatment in this patient population and examined various subgroups to determine for which, if any, the treatment is more cost-effective...
October 11, 2017: Oncologist
https://www.readbyqxmd.com/read/28983220/similar-cost-savings-of-bundled-payment-initiatives-applied-to-lower-extremity-total-joint-arthroplasty-can-be-achieved-applying-both-models-2-and-3
#14
Allyson Alfonso, Lorraine Hutzler, Bill Robb, Chad Beste, André Blom, Joseph Bosco
BACKGROUND: In an effort to control cost and increase value, Medicare is transitioning from fee-for-service to value-based alternative payment models (APMs). The Bundled Payments for Care Improvement (BPCI) initiative represents one such voluntary APM. BPCI offers four different bundling options: model 1 covers all Diagnosis Related Groups (DRGs) and Models 2-4 cover 48 clinical episodes, including 186 separate DRGs. QUESTIONS/PURPOSES: The purpose of this investigation is to analyze and compare the cost savings achieved by two different BPCI program participants, provider A and provider B, enrolled in different models of BPCI (Models 2 and 3) for lower extremity joint replacements (LEJRs)...
October 2017: HSS Journal: the Musculoskeletal Journal of Hospital for Special Surgery
https://www.readbyqxmd.com/read/28982741/serving-a-la-car-t-value-based-pricing-and-gene-therapy
#15
Margaret Tempero
No abstract text is available yet for this article.
October 2017: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/28972020/innovative-contracting-for-pharmaceuticals-and-medicaid-s-best-price-rule
#16
Rachel Sachs, Nicholas Bagley, Darius N Lakdawalla
In recent years, drug manufacturers and private payers have expressed interest in novel pricing models that more closely link a drug's price to its value. Indication-based pricing, outcome-based pricing, drug licenses, and drug mortgages have all been discussed as alternatives to paying strictly for volume. Manufacturers and payers have complained, however, that Medicaid's "best-price rule" inhibits their ability to enter into these new pricing arrangements. This article examines the best-price rule and assesses to what extent, if any, it might frustrate the goal of paying for value...
September 28, 2017: Journal of Health Politics, Policy and Law
https://www.readbyqxmd.com/read/28955404/responsible-pricing-in-value-based-assessment-of-cancer-drugs-real-world-data-are-an-inevitable-addition-to-select-meaningful-new-cancer-treatments
#17
EDITORIAL
Wim van Harten, Maarten J IJzerman
Recently, NICE was given the task of governing the Cancer Drug Fund (CDF) in the UK as the latter was criticized for allowing too many insufficiently tested drugs to be covered [1, 2]. The CDF was initiated in 2012, but immediately received criticism from several health economists because of the rather strict coverage criteria that are commonly used by NICE for most other health services in the NHS. This led to questions about the use of different reimbursement criteria (why have a different fund otherwise?) for expensive cancer drugs...
2017: Ecancermedicalscience
https://www.readbyqxmd.com/read/28944729/using-performance-based-risk-sharing-arrangements-to-address-uncertainty-in-indication-based-pricing
#18
Kai Yeung, Meng Li, Josh J Carlson
BACKGROUND: The rise in pharmaceutical expenditures in recent years has increased health care payer interest in ensuring good value for the money. Indication-based pricing (IBP) sets separate, indication-specific prices paid to the manufacturer according to the expected efficacy of a drug in each of its indications. IBP allows payers to consistently pay for value across indications. While promising, a limitation of IBP as originally conceived is that efficacy estimates are typically based on clinical trial data, which may differ from real-world effectiveness...
October 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28933010/economic-evaluation-of-dupilumab-for-the-treatment-of-moderate-to-severe-atopic-dermatitis-in-adults
#19
Andreas Kuznik, Gaëlle Bégo-Le-Bagousse, Laurent Eckert, Abhijit Gadkari, Eric Simpson, Christopher N Graham, LaStella Miles, Vera Mastey, Puneet Mahajan, Sean D Sullivan
INTRODUCTION: Dupilumab significantly improves signs and symptoms of atopic dermatitis (AD), including pruritus, symptoms of anxiety and depression, and health-related quality of life versus placebo in adults with moderate-to-severe AD. Since the cost-effectiveness of dupilumab has not been evaluated, the objective of this analysis was to estimate a value-based price range in which dupilumab would be considered cost-effective compared with supportive care (SC) for treatment of moderate-to-severe AD in an adult population...
September 20, 2017: Dermatology and Therapy
https://www.readbyqxmd.com/read/28932740/tapping-the-vast-potential-of-the-data-deluge-in-small-scale-food-animal-production-businesses-challenges-to-near-real-time-data-analysis-and-interpretation
#20
Flavie Vial, Andrew Tedder
Food-animal production businesses are part of a data-driven ecosystem shaped by stringent requirements for traceability along the value chain and the expanding capabilities of connected products. Within this sector, the generation of animal health intelligence, in particular, in terms of antimicrobial usage, is hindered by the lack of a centralized framework for data storage and usage. In this Perspective, we delimit the 11 processes required for evidence-based decisions and explore processes 3 (digital data acquisition) to 10 (communication to decision-makers) in more depth...
2017: Frontiers in Veterinary Science
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