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Prinzmetal angina

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https://www.readbyqxmd.com/read/28990946/stent-and-implantable-cardioverter-defibrillator-implantation-in-medically-resistant-vasospastic-angina-patient
#1
Nil Özyüncü, Hüseyin Göksülük, Veysel Kutay Vurgun, Onur Yıldırım, Türkan Seda Tan Kürklü
Vasospastic angina, also known as Prinzmetal's angina, is thought to occur due to vascular hyper-reactivity to various stimuli. Response to medical therapy is usually good; however, 1 out of 5 patients has resistant symptoms. Rarely, potentially lethal arrhythmias can occur due to vasospasm, and those patients are reported to have a poorer prognosis. Presently described is a case of resistant vasospastic angina with persistent symptoms under calcium channel blocker and nitrate treatment. The patient presented with hemodynamically unstable rapid-rate ventricular tachycardia, which was quite resistant to recurrent cardioversion...
October 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28877324/t786c-mutation-in-the-endothelial-nitric-oxide-synthase-gene-in-patients-with-primary-osteonecrosis
#2
Amir M Khan, Joshua Choi, Richard A Freiberg, Charles J Glueck, Naila Goldenberg, Ping Wang
Mutations in the T786C endothelial nitric oxide synthase gene (eNOS) are associated with osteonecrosis and Prinzmetal's angina. Nitric oxide is necessary for bone health and ameliorates Prinzmetal's angina. This study compared mutations of T786C eNOS in 146 patients with primary osteonecrosis, 114 patients with Prinzmetal's angina, and 83 normal control subjects. Patients with osteonecrosis had more mutant eNOS alleles than control subjects (42% vs 22%, respectively; P<.0001) but had the same number of mutant alleles as patients with Prinzmetal's angina (42% vs 41%, respectively; P=...
September 1, 2017: Orthopedics
https://www.readbyqxmd.com/read/28819899/significance-of-intravascular-ultrasound-and-exercise-stress-echocardiography-in-diagnosis-of-exercise-induced-vasospastic-angina-at-the-site-of-moderate-stenosis
#3
Makio Muraishi, Kentaro Shibayama, Masahiko Noguchi, Hiroyuki Watanabe, Kotaro Obunai
Recently, exercise-induced spastic coronary artery occlusion at the site of moderate stenosis, which Prinzmetal's angina or cardiac syndrome X does not cover, was reported. Multi-modality imaging is important for the diagnosis of coronary artery disease with a complex ischemic mechanism. However, the previous report did not include findings from intracoronary imaging at the site of moderate coronary stenosis. We report a case of exercise-induced vasospastic angina at the site of moderate stenosis, where multi-modality imaging, including exercise stress echocardiography and intravascular ultrasound, was utilized to make a definitive diagnosis and investigate underlying causes...
August 17, 2017: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/28434625/prinzmetals-angina-presenting-with-non-critical-lesion-with-normal-ffr-to-stent-or-not-to-stent
#4
EDITORIAL
Deepak Kadeli, Keshava R, Magesh B, Krishnaprasath V
Variant angina also called Prinzmetals angina is an enigma characterized by transient circadian symptoms of chest pain associated with ECG changes. The patient is symptom free with normal ECG and echo during symptom free periods. We present a case associated with transient ST-segment elevation with non critical lesion with normal FFR.
April 4, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28283339/prinzmetal-angina-coronary-vasospasm-associated-with-5-fluorouracil-chemotherapy
#5
Maxim Ben-Yakov, Amal Mattu, William J Brady, Sarah B Dubbs
Several chemotherapeutic agents are known to be cardiotoxic. One of them, 5-fluorouracil (5-FU), has been associated with coronary ischemia and reversible vasospasm. In this report, we describe a 54-year-old man with rectal cancer who developed chest pain during 5-FU infusion. His initial electrocardiogram (ECG), obtained while he was experiencing chest pain, showed hyperacute T waves in the anterolateral leads. Those waves disappeared along with the chest pain after administration of sublingual nitroglycerine...
July 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28273995/prinzmetals-angina-masquerading-as-acute-pericarditis
#6
Ashwal Adamane Jayaram, Mugula Sudhakar Rao, R Padmakumar, Uk Abdul Razak
Coronary artery spasm is an intense vasoconstriction of the coronary arteries and may be responsible for the myocardial ischemia, myocardial infarction as well as sudden deaths. Coronary angiography is generally needed to identify the cause. Coronary artery spasm is a multifactorial disease with underlying mechanism still poorly understood. Here, we present case of a 48-year-old male with no significant past history who presented with acute episodic onset chest pain. Clinical, Electrocardiography (ECG) and echocardiographic findings suggested pericarditis but a diagnostic coronary angiography revealed significant coronary vasospasm...
January 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27933173/a-rare-case-of-gestational-thyrotoxicosis-as-a-cause-of-acute-myocardial-infarction
#7
Varalaxmi Bhavani Nannaka, Dmitry Lvovsky
Angina pectoris in pregnancy is unusual and Prinzmetal's angina is much rarer. It accounts for 2% of all cases of angina. It is caused by vasospasm, but the mechanism of spasm is unknown but has been linked with hyperthyroidism in some studies. Patients with thyrotoxicosis-induced acute myocardial infarction are unusual and almost all reported cases have been associated with Graves' disease. Human chorionic gonadotropin hormone-induced hyperthyroidism occurs in about 1.4% of pregnant women, mostly when hCG levels are above 70-80 000 IU/L...
2016: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/27908388/the-unknown-association-of-ppis-with-chest-pain-in-patients-with-known-treated-coronary-artery-disease-a-diagnostic-dilemma
#8
Fahad Javed, Stephen Ramee
Patients with coronary artery disease (CAD) are destined to lifelong antiplatelet therapy in form of aspirin (acetylsalicylic acid) alone, or in combination with other P2Y2 inhibitors. Proton pump inhibitors (PPIs) are the preferred agents for the treatment and prophylaxis of gastrointestinal injury associated with nonsteroidal anti-inflammatory drug or acetylsalicylic acid or both,(1) but recent data has raised questions about their association with negative cardiovascular events. We report 2 cases of patients with known CAD presented with chest pain mimicking angina pectoris that successfully resolved on discontinuation of the PPIs...
July 2016: Current Problems in Cardiology
https://www.readbyqxmd.com/read/27557062/-statins-potentially-improve-prognosis-of-prinzmetal-s-angina-patients
#9
Ulrich Tebbe
No abstract text is available yet for this article.
August 2016: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/26307648/an-atypical-case-of-vasospastic-angina-demonstrating-the-usefulness-of-holter-monitoring
#10
Naveen Chandra Ganiga Sanjeeva, Ranjan K Shetty, Sumit Agarwal
Prinzmetal variant angina or vasospastic angina is a clinical syndrome characterised by episodic chest pain and transient reversible ST segment changes in ECG. The aetiology and treatment of the condition are quite different compared to those of conventional coronary artery disease. The crux of the problem in variant angina patients remains the diagnosis, especially if coexisting coronary artery disease is present. Timely diagnosis not only helps relieve symptoms, it also prevents complications such as ventricular tachycardia...
August 25, 2015: BMJ Case Reports
https://www.readbyqxmd.com/read/26238940/the-usefulness-of-spinal-cord-stimulation-for-chronic-pain-due-to-combined-vasospastic-prinzmetal-angina-and-diabetic-neuropathic-pain-of-the-lower-limbs
#11
Thomas M Kinfe, Bogdan Pintea
OBJECTIVE: To describe an unusual case of combined neuropathic and ischemia-induced chronic pain in a patient who was treated with one high thoracic paddle lead. BACKGROUND: To the best of our knowledge, the use of spinal cord stimulation (SCS) utilizing a single lead as a treatment strategy for combined Prinzmetal angina, a cardiac ischemia-induced disturbance of nociceptive perception, and diabetic neuropathy of the lower limbs has rarely been described. CASE REPORT: The underlying pain conditions and SCS technique used to treat both types of pain-Prinzmetal angina and lower-limb diabetic neuropathy-in a 73-year-old patient experiencing medical or interventional refractory complex pain syndrome are described...
March 2016: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/26034323/recurrent-myocardial-infarction-secondary-to-prinzmetal-s-variant-angina
#12
Dale Murdoch, Priyanka Dhillon, Selvanayagam Niranjan
Prinzmetal's variant angina describes chest pain secondary to reversible coronary artery vasospasm in the context of both diseased and non-diseased coronary arteries. Symptoms typically occur when the patient is at rest and are associated with transient ST-segment elevation. Acute episodes respond to glyceryl trinitrate, but myocardial infarction and other potentially fatal complications can occur, and long-term management can be challenging. Although it is not well understood, the underlying mechanism appears to involve a combination of endothelial damage and vasoactive mediators...
May 2015: Singapore Medical Journal
https://www.readbyqxmd.com/read/26025204/double-hazards-of-ischemia-and-reperfusion-arrhythmias-in-a-patient-with-variant-angina-pectoris
#13
Mingzhu Xu, Xiangjun Yang
Variant angina pectoris, also called Prinzmetal's angina, is a syndrome caused by vasospasms of the coronary arteries. It can lead to myocardial infarction, ventricular arrhythmias, atrioventricular block and even sudden cardiac death. We report the case of a 53 year-old male patient with recurrent episodes of chest pain and arrhythmias in the course of related variant angina pectoris. It is likely that the reperfusion following myocardial ischemia was responsible for the ventricular fibrillation while the ST-segment returned to the baseline...
July 2015: Journal of Electrocardiology
https://www.readbyqxmd.com/read/25945908/-prinzmetal-angina-after-licorice-consumption
#14
Kathrin Machalke, Peter Bramlage, Karin Bramlage, Ulrich Tebbe
Medical history | We report on a 44-year-old patient with recurrent thoracic pain occurring 4 months apart. The patient complained about intense thoracic pain and acute dyspnoea in the morning. In the course of the second presentation the anamnesis revealed that the previous day the patient had consumed an entire bag of licorice (200 g). Investigations | The blood pressure was 90/65 mmHg, heart rate 68 beats / min. Neither the performed ECG nor the transthoracic echocardiography showed abnormalities...
April 2015: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/25782126/-ventriculer-fibrillation-due-to-prinzmetal-angina-in-a-pregnant-patient
#15
Ahmet Gündeş, Ahmet Çelik, İsmail Türkay Özcan, Ahmet Çamsarı
Variant angina, which is also referred to as prinzmetal or coronary vasospastic angina, is a clinical entity characterized by episodes of angina pectoris, usually at rest and often between midnight and early morning, in association with ST-segment elevation on the electrocardiogram. Angina is usually caused by focal spasm of a major coronary artery resulting in a high-grade obstruction, and myocardial infarction may develop in some cases. We report a prinzmetal angina which caused ventricular fibrillation and cardiac arrest in an 18-week pregnant woman...
March 2015: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/25262663/prinzmetal-angina-ecg-changes-and-clinical-considerations-a-consensus-paper
#16
REVIEW
Antonio Bayés de Luna, Iwona Cygankiewicz, Adrian Baranchuk, Miquel Fiol, Yochai Birnbaum, Kjell Nikus, Diego Goldwasser, Javier Garcia-Niebla, Samuel Sclarovsky, Hein Wellens, Günter Breithardt
BACKGROUND: We will focus our attention in this article in the ECG changes of classical Prinzmetal angina that occur during occlusive proximal coronary spasm usually in patients with normal or noncritical coronary stenosis. RESULTS: The most important ECG change during a focal proximal coronary spasm is in around 50% of cases the appearance of peaked and symmetrical T wave that is followed, if the spasm persist, by progressive ST-segment elevation that last for a few minutes, and later progressively resolve...
September 2014: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/25222381/a-rare-case-of-prinzmetal-angina-3-days-after-coronary-artery-stenting-with-a-second-generation-drug-eluting-stent
#17
Vincenzo Sucato, Angela Sansone, Salvatore Evola, Giuseppina Novo, Giuseppe Coppola, Egle Corrado, Antonino Rotolo, Giuseppe Andolina, Salvatore Novo, Pasquale Assennato
No abstract text is available yet for this article.
January 2015: Coronary Artery Disease
https://www.readbyqxmd.com/read/25129838/diurnal-and-twenty-four-hour-patterning-of-human-diseases-cardiac-vascular-and-respiratory-diseases-conditions-and-syndromes
#18
REVIEW
Michael H Smolensky, Francesco Portaluppi, Roberto Manfredini, Ramon C Hermida, Ruana Tiseo, Linda L Sackett-Lundeen, Erhard L Haus
Various medical conditions, disorders, and syndromes exhibit predictable-in-time diurnal and 24 h patterning in the signs, symptoms, and grave nonfatal and fatal events, e.g., respiratory ones of viral and allergic rhinorrhea, reversible (asthma) and non-reversible (bronchitis and emphysema) chronic obstructive pulmonary disease, cystic fibrosis, high altitude pulmonary edema, and decompression sickness; cardiac ones of atrial premature beats and tachycardia, paroxysmal atrial fibrillation, 3rd degree atrial-ventricular block, paroxysmal supraventricular tachycardia, ventricular premature beats, ventricular tachyarrhythmia, symptomatic and non-symptomatic angina pectoris, Prinzmetal vasospastic variant angina, acute (non-fatal and fatal) incidents of myocardial infarction, sudden cardiac arrest, in-bed sudden death syndrome of type-1 diabetes, acute cardiogenic pulmonary edema, and heart failure; vascular and circulatory system ones of hypertension, acute orthostatic postprandial, micturition, and defecation hypotension/syncope, intermittent claudication, venous insufficiency, standing occupation leg edema, arterial and venous branch occlusion of the eye, menopausal hot flash, sickle cell syndrome, abdominal, aortic, and thoracic dissections, pulmonary thromboembolism, and deep venous thrombosis, and cerebrovascular transient ischemic attack and hemorrhagic and ischemic stroke...
June 2015: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/25029716/ask-the-doctor-what-is-prinzmetal-s-angina-a-doctor-recently-told-my-wife-that-she-might-have-prinzmetal-s-angina-what-is-this-condition-and-how-is-it-treated
#19
Deepak L Bhatt
No abstract text is available yet for this article.
June 2014: Harvard Heart Letter: From Harvard Medical School
https://www.readbyqxmd.com/read/24826293/a-series-of-unfortunate-events-prinzmetal-angina-culminating-in-transmural-infarction-in-the-setting-of-acute-gastrointestinal-hemorrhage
#20
Michael Ruisi, Phillip Ruisi, Hugo Rosero, Paul Schweitzer
Prinzmetal angina or vasospastic angina is a clinical phenomenon that is often transient and self-resolving. Clinically it is associated with ST elevations on the electrocardiogram, and initially it may be difficult to differentiate from an acute myocardial infarction. The vasospasm induced in this setting occurs in normal or mildly to moderately diseased vessels and can be triggered by a number of etiologies including smoking, changes in autonomic activity, or drug ingestion. While the ischemia induced is usually transient, myocardial infarction and life-threatening arrhythmias can occur in 25% of cases...
2013: Case Reports in Cardiology
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