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https://www.readbyqxmd.com/read/27920493/a-retrospective-analysis-of-intraocular-pressure-changes-after-cataract-surgery-with-the-use-of-prednisolone-acetate-1-versus-difluprednate-0-05
#1
Yael Kusne, Paul Kang, Robert E Fintelmann
PURPOSE: To compare the effect of topical prednisolone acetate 1% (PA) used after routine cataract surgery to the effect of difluprednate 0.05% (DFBA) used for the same indication on intraocular pressure (IOP). METHODS: An electronic query was created to gather information from all cataract surgeries between January 2010 and January 2015 within the electronic health record database at Barnet Dulaney Perkins, a multicenter, multiphysician private practice in Phoenix, Arizona...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27920137/oncogenic-met-as-an-effective-therapeutic-target-in-non-small-cell-lung-cancer-resistant-to-egfr-inhibitors-the-rise-of-the-phoenix
#2
Livio Trusolino
Anecdotal reports have shown that concomitant inhibition of EGFR and MET can be clinically effective in patients with non-small cell lung cancer carrying EGFR mutations and MET amplification, but large phase III trials in genetically unselected individuals have failed to confirm the benefit of this combination therapy. A new study corroborates the evidence that lung cancer susceptibility to EGFR and MET blockade is sustained by genetically based activation of both targets and identifies a mutation in MET that confers acquired resistance to standard MET inhibitors hitting the active kinase, yet is vulnerable to other MET-directed compounds with a different binding mode...
December 2016: Cancer Discovery
https://www.readbyqxmd.com/read/27919982/clinical-significance-of-the-apparent-diffusion-coefficient-ratio-in-prostate-cancer-treatment-with-intensity-modulated-radiotherapy
#3
Hiroko Yamaguchi, Masatoshi Hori, Osamu Suzuki, Yuji Seo, Fumiaki Isohashi, Yasuo Yoshioka, Iori Sumida, Motohide Uemura, Kazutoshi Fujita, Akira Nagahara, Takeshi Ujike, Atsunari Kawashima, Norio Nonomura, Noriyuki Tomiyama, Kazuhiko Ogawa
AIM: We aimed to investigate the correlation between biochemical recurrence (BCR) and the pretreatment apparent diffusion coefficient (ADC) ratio of tumor to normal prostate tissue in patients with prostate cancer who underwent intensity-modulated radiotherapy (IMRT). PATIENTS AND METHODS: Retrospective analyses were performed for 101 patients diagnosed with localized prostate cancer who underwent IMRT at a dose of 70-78 Gy to the prostate gland and medial part of the seminal vesicles...
December 2016: Anticancer Research
https://www.readbyqxmd.com/read/27912028/formation-and-persistence-of-brine-on-mars-experimental-simulations-throughout-the-diurnal-cycle-at-the-phoenix-landing-site
#4
E Fischer, G M Martínez, N O Rennó
In the last few years, water ice and salts capable of melting this ice and producing liquid saline water (brine) have been detected on Mars. Moreover, indirect evidence for brine has been found in multiple areas of the planet. Here, we simulate full diurnal cycles of temperature and atmospheric water vapor content at the Phoenix landing site for the first time and show experimentally that, in spite of the low Mars-like chamber temperature, brine forms minutes after the ground temperature exceeds the eutectic temperature of salts in contact with water ice...
December 2, 2016: Astrobiology
https://www.readbyqxmd.com/read/27910524/spatially-resolved-thomson-scattering-measurements-of-the-transition-from-the-collective-to-the-non-collective-regime-in-a-laser-produced-plasma
#5
D B Schaeffer, C G Constantin, A S Bondarenko, E T Everson, C Niemann
We present optical Thomson scattering results that image for the first time in a single measurement the spatial transition from collective to non-collective scattering. Data were taken in the Phoenix laser laboratory at the University of California, Los Angeles. The Raptor laser was used to ablate a carbon plasma, which was diagnosed with the frequency-doubled Phoenix laser serving as a Thomson scattering probe. Scattered light was collected from the laser plasma up to 10 cm from the target surface and up to 10 us after ablation, and imaged with high spatial and spectral resolutions...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910108/a-day-in-the-life-of-a-m%C3%A3-ni%C3%A3-re-s-patient-understanding-the-lived-experiences-and-mental-health-impacts-of-m%C3%A3-ni%C3%A3-re-s-disease
#6
Sarah L Bell, Jessica Tyrrell, Cassandra Phoenix
Concepts of social practice are increasingly being used to understand experiences of everyday life, particularly in relation to consumption and healthy lifestyles. This article builds on this in the context of lives disrupted and reshaped by chronic illness. It uses social practice theory to examine the lived experiences of individuals with Ménière's disease; a long-term progressive vestibular disorder, defined by episodes of severe and debilitating vertigo, aural fullness, tinnitus and sensorineural hearing loss...
December 2, 2016: Sociology of Health & Illness
https://www.readbyqxmd.com/read/27902833/evaluation-of-ischemic-and-bleeding-risks-associated-with-2-parenteral-antiplatelet-strategies-comparing-cangrelor-with-glycoprotein-iib-iiia-inhibitors-an-exploratory-analysis-from-the-champion-trials
#7
Muthiah Vaduganathan, Robert A Harrington, Gregg W Stone, Efthymios N Deliargyris, Ph Gabriel Steg, C Michael Gibson, Christian W Hamm, Matthew J Price, Alberto Menozzi, Jayne Prats, Steven Elkin, Kenneth W Mahaffey, Harvey D White, Deepak L Bhatt
Importance: In the context of contemporary pharmacotherapy, optimal antiplatelet management with percutaneous coronary intervention (PCI) has not been well established. Objective: To compare the ischemic and bleeding risks associated with glycoprotein IIb/IIIa inhibitors (GPIs) and a potent P2Y12 antagonist, cangrelor, in patients undergoing PCI. Design, Setting, and Participants: An exploratory analysis of pooled patient-level data from the 3 phase 3 Cangrelor vs Standard Therapy to Achieve Optimal Management of Platelet Inhibition (CHAMPION PCI, CHAMPION PLATFORM, and CHAMPION PHOENIX) trials of patients undergoing elective or nonelective PCI...
November 30, 2016: JAMA Cardiology
https://www.readbyqxmd.com/read/27900104/prostate-specific-antigen-nadir-concentration-hypertension-and-diabetes-as-risk-factors-for-biochemical-failure-after-permanent-125-i-seed-brachytherapy-for-prostate-cancer
#8
Essi Kovalainen, Markku H Vaarala
The aim of this study was to evaluate risk factors for biochemical failure (BF) following permanent prostate seed (125)I brachytherapy for prostate cancer. The study reviewed the medical records of 607 patients with biopsy-proven prostate adenocarcinoma who were treated at Oulu University Hospital between 2001 and 2014. Clinical characteristics at diagnosis, treatment-related data and follow-up data were collected to identify potential risk factors for BF, which was defined using the Phoenix criteria [prostate-specific antigen (PSA) increase >2 µg/l from the PSA nadir concentration, which defined as the lowest PSA concentration observed after BT]...
November 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/27889878/same-day-identification-and-antibiotic-susceptibility-testing-on-positive-blood-cultures-a-simple-and-inexpensive-procedure
#9
K Maelegheer, E Nulens
Fast diagnostic tools are becoming a hot topic in microbiology, especially in the case of septic patients. Therefore, we attempted to develop a fast, inexpensive, accurate and easy method to identify bacteria and perform an antibiotic susceptibility test directly on positive blood cultures that could be used in a routine laboratory. A procedure based on centrifugation and washing steps was performed on 110 non-duplicated (including nine seeded) positive blood culture bottles. Direct identification (DID) and antimicrobial susceptibility testing (AST) was conducted on the pellet with the MALDI Biotyper and Phoenix, respectively...
November 26, 2016: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/27883359/the-contributions-of-dr-alfred-gysi
#10
Rodney D Phoenix, Robert L Engelmeier
This article is a historical overview of Dr. Alfred Gysi's contributions to the profession in the areas of denture tooth and articulator design. His understanding of occlusion and mandibular movement resulted in denture tooth designs and occlusal concepts still in widespread use.
November 24, 2016: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/27865047/carbon-lost-and-carbon-gained-a-study-of-vegetation-and-carbon-tradeoffs-among-diverse-land-uses-in-the-phoenix-az
#11
Melissa R McHale, Sharon Hall, Anandamayee Majumdar, Nancy B Grimm
Human modification and management of urban landscapes drastically alters vegetation and soils, thereby altering carbon (C) storage and rates of net primary productivity (NPP). Complex social and ecological processes drive vegetation cover in cities, leading to heterogeneity in C dynamics depending on regional climate, land use, and land cover. Recent work has demonstrated homogenization in ecological processes within human-dominated landscapes (the urban convergence hypothesis) in soils and biotic communities...
November 19, 2016: Ecological Applications: a Publication of the Ecological Society of America
https://www.readbyqxmd.com/read/27864102/a-health-sciences-student-run-smoking-cessation-clinic-experience-within-a-homeless-population
#12
Kelsey Buckley, Laura Tsu, Sabrina Hormann, Kevin Giang, April Bills, Nicole Early, Rebekah Jackowski
OBJECTIVE: The primary objective is to describe a professional and graduate student-run approach to smoking cessation education combined with motivational interviewing and pharmacotherapy in regard to the frequency of follow-up with a smoking cessation quitline program in the homeless population. The secondary objective is to assess participants' self-reported level of confidence, knowledge, and willingness to quit before and after participation in the student-run smoking cessation clinic...
November 15, 2016: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/27857368/simplified-modeling-and-optimization-of-silicon-modulators-based-on-free-carrier-plasma-dispersion-effect
#13
D Pérez-Galacho, D Marris-Morini, R Stoffer, E Cassan, C Baudot, T Korthorst, F Boeuf, L Vivien
In this paper, a simplified model of silicon phase modulators is presented that enables favorable accuracy together with a substantial reduction in computational effort and without the requirement of semiconductor TCAD device simulation software. This permits fast optimization of the different parameters of a modulator. The model was successfully implemented in Phoenix Optodesigner optical software allowing the optimization of silicon phase shifters for different applications. Moreover, this model presents a great potential for the simulation of modulators based on PN interdigitated junctions, which normally require complex and time consuming 3D simulations...
November 14, 2016: Optics Express
https://www.readbyqxmd.com/read/27855704/feeding-preferences-of-the-asian-elephant-elephas-maximus-in-nepal
#14
Raj Kumar Koirala, David Raubenheimer, Achyut Aryal, Mitra Lal Pathak, Weihong Ji
BACKGROUND: Nepal provides habitat for approximately 100-125 wild Asian elephants (Elephas maximus). Although a small proportion of the world population of this species, this group is important for maintaining the genetic diversity of elephants and conservation of biodiversity in this region. Knowledge of foraging patterns of these animals, which is important for understanding their habitat requirements and for assessing their habitat condition, is lacking for the main areas populated by elephants in Nepal...
November 17, 2016: BMC Ecology
https://www.readbyqxmd.com/read/27847237/compositional-and-structural-changes-in-phoenix-canariensis-and-opuntia-ficus-indica-with-pretreatment-effects-on-enzymatic-hydrolysis-and-second-generation-ethanol-production
#15
Benard Anayo Udeh, Emrah Ahmet Erkurt
Two different plants namely Phoenix canariensis and Opuntia ficus-indica were used as substrate for reducing sugar generation and ethanol production. Dilute acid, alkaline and steam explosion were used as pretreatment methods in order to depolymerize lignin and/or hemicellulose and recover cellulose. By using alkaline pretreatment with 2.5% NaOH 71.08% for P. canariensis and 74.61% for O. ficus-indica lignin removal and 81.84% for P. canariensis and 72.66% for O. ficus-indica cellulose recovery yields were obtained...
November 5, 2016: Bioresource Technology
https://www.readbyqxmd.com/read/27834116/ethanol-based-proliposome-delivery-systems-of-paclitaxel-for-in-vitro-application-against-brain-cancer-cells
#16
Mohammad Najlah, Mohit Jain, Ka-Wai Wan, Waqar Ahmed, Mohamed Albed Alhnan, David A Phoenix, Kevin M G Taylor, Abdelbary Elhissi
In this study the anticancer activity of paclitaxel-loaded nano-liposomes on glioma cell lines was investigated. Soya phosphatidylcholine: cholesterol (SPC:Chol), hydrogenated soya phosphatidylcholine: cholesterol (HSPC:Chol) or dipalmitoylphosphatidylcholine: cholesterol (DPPC:Chol) in 1:1 mole ratio were used to prepare ethanol-based proliposomes. Following hydration of proliposomes, the size of resulting vesicles was subsequently reduced to nanometre scale via probe-sonication. The resulting formulations were characterised in terms of size, zeta potential and morphology of the vesicles, and entrapment efficiency of paclitaxel (PX) as well as the final pH of the preparations...
November 11, 2016: Journal of Liposome Research
https://www.readbyqxmd.com/read/27826307/genome-wide-identification-and-transferability-of-microsatellite-markers-between-palmae-species
#17
Yong Xiao, Wei Xia, Jianwei Ma, Annaliese S Mason, Haikuo Fan, Peng Shi, Xintao Lei, Zilong Ma, Ming Peng
The Palmae family contains 202 genera and approximately 2800 species. Except for Elaeis guineensis and Phoenix dactylifera, almost no genetic and genomic information is available for Palmae species. Therefore, this is an obstacle to the conservation and genetic assessment of Palmae species, especially those that are currently endangered. The study was performed to develop a large number of microsatellite markers which can be used for genetic analysis in different Palmae species. Based on the assembled genome of E...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27825278/resilience-associated-with-mental-health-problems-among-methadone-maintenance-treatment-patients-in-guangzhou-china
#18
Mingxu Jiao, Jing Gu, Huifang Xu, Chun Hao, Joseph T F Lau, Phoenix Mo, Di Liu, Yuteng Zhao, Xiao Zhang, Andrew Babbitt, Yuantao Hao
A considerable proportion of methadone maintenance treatment (MMT) clients have experienced mental health problems (e.g., depression and anxiety), and poor mental health status is associated with HIV-related risk behaviors and treatment drop-out. Resilience is known to be a protective factor for mental health problems but is not studied among MMT clients in China. This study aimed to explore the relationship between resilience and mental health problems (depression, anxiety and stress) among clients of community-based MMT clinics in China...
November 8, 2016: AIDS Care
https://www.readbyqxmd.com/read/27824922/identification-of-reference-genes-for-quantitative-real-time-pcr-in-date-palm-phoenix-dactylifera-l-subjected-to-drought-and-salinity
#19
Himanshu V Patankar, Dekoum V M Assaha, Rashid Al-Yahyai, Ramanjulu Sunkar, Mahmoud W Yaish
Date palm is an important crop plant in the arid and semi-arid regions supporting human population in the Middle East and North Africa. These areas have been largely affected by drought and salinity due to insufficient rainfall and improper irrigation practices. Date palm is a relatively salt- and drought-tolerant plant and more recently efforts have been directed to identifying genes and pathways that confer stress tolerance in this species. Quantitative real-time PCR (qPCR) is a promising technique for the analysis of stress-induced differential gene expression, which involves the use of stable reference genes for normalizing gene expression...
2016: PloS One
https://www.readbyqxmd.com/read/27823925/application-of-a-lc-ms-ms-method-for-evaluating-lung-penetration-of-tobramycin-in-rats-by-microdialysis
#20
P M Bernardi, F Barreto, T Dalla Costa
A bioanalytical LC-MS/MS method was developed and validated to determine tobramycin in plasma and lung microdialysate samples. Tobramycin was separated using a C18 column and a mobile phase consisting of water and acetonitrile, both with 10mM of heptafluorobutyric acid, eluted as gradient. Apramycin was used as internal standard (IS) for plasma samples. Drugs were monitored using electrospray ionization operating on positive mode (ESI+) monitoring the transitions 468.2>163.3 m/z for tobramycin and 540.3>217...
October 27, 2016: Journal of Pharmaceutical and Biomedical Analysis
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