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https://www.readbyqxmd.com/read/28342956/disparities-in-telephone-cpr-access-and-timing-during-out-of-hospital-cardiac-arrest
#1
Tomas Nuño, Bentley J Bobrow, Karen A Rogge-Miller, Micah Panczyk, Terry Mullins, Wayne Tormala, Antonio Estrada, Samuel M Keim, Daniel W Spaite
AIM: Spanish-only speaking residents in the United States face barriers to receiving potentially life-saving 911 interventions such as Telephone -cardiopulmonary resuscitation (TCPR) instructions. Since 2015, 911 dispatchers have placed an increased emphasis on rapid identification of potential cardiac arrest. The purpose of this study was to describe the utilization and timing of the 911 system during suspected OHCA by Spanish-speaking callers in Metropolitan Phoenix, Arizona. METHODS: The dataset consisted of suspected OHCA from 911 centers from October 10, 2010 through December 31, 2013...
March 22, 2017: Resuscitation
https://www.readbyqxmd.com/read/28340405/population-pharmacokinetic-modeling-of-furosemide-in-patients-with-hypertension-and-fluid-overload-conditions
#2
Devender Kodati, Narsimhareddy Yellu
BACKGROUND: Furosemide is a loop diuretic drug frequently indicated in hypertension and fluid overload conditions such as congestive heart failure and hepatic cirrhosis. OBJECTIVE: The purpose of the study was to establish a population pharmacokinetic model for furosemide in Indian hypertensive and fluid overload patients, and to evaluate effects of covariates on the volume of distribution (V/F) and oral clearance (CL/F) of furosemide. METHODS: A total of 188 furosemide plasma sample concentrations from 63 patients with hypertension or fluid overload conditions were collected in this study...
January 15, 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/28330456/genome-wide-expression-profiling-in-leaves-and-roots-of-date-palm-phoenix-dactylifera-l-exposed-to-salinity
#3
Mahmoud W Yaish, Himanshu V Patankar, Dekoum V M Assaha, Yun Zheng, Rashid Al-Yahyai, Ramanjulu Sunkar
BACKGROUND: Date palm, as one of the most important fruit crops in North African and West Asian countries including Oman, is facing serious growth problems due to salinity, arising from persistent use of saline water for irrigation. Although date palm is a relatively salt-tolerant plant species, its adaptive mechanisms to salt stress are largely unknown. RESULTS: In order to get an insight into molecular mechanisms of salt tolerance, RNA was profiled in leaves and roots of date palm seedlings subjected to NaCl for 10 days...
March 22, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28330400/academic-responses-to-fukushima-disaster
#4
Kiyotaka Yasui, Yuko Kimura, Kenji Kamiya, Rie Miyatani, Naohiro Tsuyama, Akira Sakai, Koji Yoshida, Shunichi Yamashita, Rethy Chhem, May Abdel-Wahab, Akira Ohtsuru
Since radiation accidents, particularly nuclear disasters, are rarer than other types of disasters, a comprehensive radiation disaster medical curriculum for them is currently unavailable. The Fukushima compound disaster has urged the establishment of a new medical curriculum in preparation for any future complex disaster. The medical education will aim to aid decision making on various health risks for workers, vulnerable people, and residents addressing each phase in the disaster. Herein, we introduce 3 novel educational programs that have been initiated to provide students, professionals, and leaders with the knowledge of and skills to elude the social consequences of complex nuclear disasters...
March 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/28330181/optimization-of-medium-composition-for-in-vitro-shoot-proliferation-and-growth-of-date-palm-cv-mejhoul
#5
Mouaad Amine Mazri, Reda Meziani, Jamal El Fadile, Az-Eddine Ezzinbi
The effects of major mineral salts, L-glutamine, myo-inositol and carbon source on shoot bud proliferation of date palm (Phoenix dactylifera L.) cv. Mejhoul were evaluated. Different concentrations of ammonium nitrate (NH4NO3; 550, 825 or 1650 mg/L), potassium nitrate (KNO3; 633.3, 950 or 1900 mg/L), calcium chloride dehydrate (CaCl2·2H2O; 147, 220 or 440 mg/L), potassium dihydrogen phosphate (KH2PO4; 57, 85 or 170 mg/L), magnesium sulfate heptahydrate (MgSO4·7H2O; 123, 185 or 370 mg/L), L-glutamine and myo-inositol (0...
June 2016: 3 Biotech
https://www.readbyqxmd.com/read/28330092/development-of-molecular-method-for-sex-identification-in-date-palm-phoenix-dactylifera-l-plantlets-using-novel-sex-linked-microsatellite-markers
#6
Maryam, Muhammad Jafar Jaskani, Faisal Saeed Awan, Saeed Ahmad, Iqrar A Khan
Microsatellite markers containing simple sequence repeats (SSRs) are a valuable tool for genetic analysis. Date palm is a dioecious and slow flowering and is very difficult to identify the gender of the trees until it reaches the reproductive age (5-10 years). A total of 12 microsatellite primers were used with 30 date palm samples, 14 parents (8 male + 6 females) and 16 progeny (developed from parents breeding) which showed that microsatellites were highly polymorphic, having a great number of alleles. A total of 124 alleles were characterized in 12 SSR loci...
June 2016: 3 Biotech
https://www.readbyqxmd.com/read/28293229/fungal-root-microbiome-from-healthy-and-brittle-leaf-diseased-date-palm-trees-phoenix-dactylifera-l-reveals-a-hidden-untapped-arsenal-of-antibacterial-and-broad-spectrum-antifungal-secondary-metabolites
#7
Fedia B Mefteh, Amal Daoud, Ali Chenari Bouket, Faizah N Alenezi, Lenka Luptakova, Mostafa E Rateb, Adel Kadri, Neji Gharsallah, Lassaad Belbahri
In this study, we aimed to explore and compare the composition, metabolic diversity and antimicrobial potential of endophytic fungi colonizing internal tissues of healthy and brittle leaf diseased (BLD) date palm trees (Phoenix dactylifera L.) widely cultivated in arid zones of Tunisia. A total of 52 endophytic fungi were isolated from healthy and BLD roots of date palm trees, identified based on internal transcribed spacer-rDNA sequence analysis and shown to represent 13 species belonging to five genera. About 36...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28283988/nicotine-population-pharmacokinetics-in-healthy-adult-smokers-a-retrospective-analysis
#8
Mathilde Marchand, Patrick Brossard, Henri Merdjan, Nicola Lama, Rolf Weitkunat, Frank Lüdicke
BACKGROUND AND OBJECTIVE: Characterizing nicotine pharmacokinetics is challenging in the presence of background exposure. We performed a combined retrospective population pharmacokinetic analysis of 8 trials, including exposure to Tobacco Heating System and cigarettes (both inhaled), nicotine nasal spray and oral nicotine gum. METHOD: Data from 4 single product use trials were used to develop a population pharmacokinetic model with Phoenix(®) NLME™ and to derive exposure parameters...
March 10, 2017: European Journal of Drug Metabolism and Pharmacokinetics
https://www.readbyqxmd.com/read/28271717/low-sustainability-poor-governance-and-other-challenges-encountered-by-grassroots-non-governmental-organizations-targeting-hiv-prevention-for-men-who-have-sex-with-men-in-china-a-nation-wide-study
#9
Joseph T F Lau, Zixin Wang, Yoona Kim, Jinghua Li, Jing Gu, Phoenix K H Mo, Xiaodong Wang
Grassroots non-governmental organizations (NGOs) played pivotal roles in HIV prevention among men who have sex with men (MSM) in China. Their governance and sustainability issues were under-studied. This nation-wide study surveyed leaders of 202 of the HIV related NGOs in China.58.4% of the leaders believed that their NGO would last for ≤5 years; which was negatively associated with perceived good relationship with CDC. 65.3% mentioned ≥3 non-sustainability issues; associated factors included perceived inadequacies in prevention skills, management skills, policy support, technical support, operational support, and CDC's support; a reverse association was found for frequent collaboration with organizations in China...
March 8, 2017: AIDS Care
https://www.readbyqxmd.com/read/28258616/focal-salvage-hifu-in-radiorecurrent-prostate-cancer
#10
A Kanthabalan, M Peters, M Van Vulpen, N McCartan, R G Hindley, A Emara, M C Moore, M Arya, M Emberton, H U Ahmed
OBJECTIVE: To assess short to medium term cancer control rates and side effects of focal salvage High Intensity Focused Ultrasound (HIFU). MATERIALS AND METHODS: A retrospective registry analysis identified 150 men who underwent focal salvage HIFU (Sonablate 500) (November 2006-August 2015). Metastatic disease was excluded using the nodal assessment on the pelvic MRI, a radioisotope bone scan and PET imaging (choline-FDG-PET or Choline PET-CT). In our current clinical practice, metastatic disease must be ruled out by both Choline PET and bone scan...
March 4, 2017: BJU International
https://www.readbyqxmd.com/read/28258334/the-occupy-central-umbrella-movement-and-mental-health-distress-in-the-hong-kong-general-public-political-movements-and-concerns-as-potential-structural-risk-factors-of-population-mental-health
#11
Joseph T F Lau, Yoona Kim, Anise M S Wu, Zixin Wang, Bishan Huang, Phoenix K H Mo
PURPOSE: Political tension, as expressed by mass movements such as the Occupy Central movement (2014) in Hong Kong, is a potential but understudied structural factor of population mental health. METHODS: A random population-based telephone survey anonymously interviewed 344 Hong Kong Chinese adults aged 18-65 years during the 2 weeks since the termination date of the 2-month-long Occupy Central movement (15/12/2014). Linear regression models were fit using mental distress (depression, anxiety and negative mood) and self-perceived changes in mood/sleeping quality as dependent variables...
March 3, 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/28257091/tentative-characterization-of-polyphenolic-compounds-in-the-male-flowers-of-phoenix-dactylifera-by-liquid-chromatography-coupled-with-mass-spectrometry-and-dft
#12
Ridha Ben Said, Arafa I Hamed, Usam A Mahalel, Abdullah Sulaiman Al-Ayed, Mariusz Kowalczyk, Jaroslaw Moldoch, Wieslaw Oleszek, Anna Stochmal
Phoenix dacylifera is an ancient palm species rich in (poly)phenols. These phenolic compounds were tentatively identified by using liquid chromatography coupled with ion spray mass spectrometry in tandem mode (LC/MS/MS) with negative ion detection. Negative identification of the compounds was based on their retention times and mass spectra in full scan mode (MS), and in different MS/MS modes. For the first time, complete hypothesis, and routs for both p-coumaroylshikimic acids (CoSA) and caffeoylshikimic acids (CSA) were suggested and confirmed by Density Fonctional Theory (DFT) study...
March 2, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28254367/endophytic-fungi-associated-with-roots-of-date-palm-phoenix-dactylifera-in-coastal-dunes
#13
Fadila Mohamed Mahmoud, Zoulikha Krimi, Jose G Maciá-Vicente, Mohamed Brahim Errahmani, Luis V Lopez-Llorca
BACKGROUND: Symbiotic interactions with fungal endophytes are argued to be responsible for the tolerance of plants to some stresses and for their adaptation to natural conditions. AIMS: In this study we aimed to examine the endophytic fungal diversity associated with roots of date palms growing in coastal dune systems, and to screen this collection of endophytes for potential use as biocontrol agents, for antagonistic activity and mycoparasitism, and as producers of antifungal compounds with potential efficacy against root diseases of date palm...
February 26, 2017: Revista Iberoamericana de Micología
https://www.readbyqxmd.com/read/28254068/phxnlme-an-r-package-that-facilitates-pharmacometric-workflow-of-phoenix-nlme-analyses
#14
Chay Ngee Lim, Shuang Liang, Kevin Feng, Jason Chittenden, Ana Henry, Samer Mouksassi, Angela K Birnbaum
BACKGROUND AND OBJECTIVE: Pharmacometric analyses are integral components of the drug development process, and Phoenix NLME is one of the popular software used to conduct such analyses. To address current limitations with model diagnostic graphics and efficiency of the workflow for this software, we developed an R package, Phxnlme, to facilitate its workflow and provide improved graphical diagnostics. METHODS: Phxnlme was designed to provide functionality for the major tasks that are usually performed in pharmacometric analyses (i...
March 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28250657/short-term-effects-of-date-palm-extract-phoenix-dactylifera-on-ischemia-reperfusion-injury-induced-by-testicular-torsion-detorsion-in-rats
#15
Alireza Raayat Jahromi, Rokhsana Rasooli, Younes Kamali, Nasrollah Ahmadi, Ehsan Sattari
BACKGROUND: Antioxidants are potent scavengers of free radicals and have beneficial effects on human health. OBJECTIVE: The aim of this study was to investigate the potential protective antioxidant activity of the edible portion of date fruit extract in an experimental testicular torsion/detorsion (T/D) model in rats. MATERIALS AND METHODS: To investigate the potential protective effects of date palm (DP), 30 male Spraque-Dawley rats were divided into three groups: sham-operated, T/D, and T/D + DP-treated (500 mg/kg, PO) groups...
January 2017: Pharmacognosy Research
https://www.readbyqxmd.com/read/28249727/maximin-h5-is-an-anticancer-peptide
#16
Sarah R Dennison, Frederick Harris, David A Phoenix
Here we report the first major example of anionic amphibian host defence peptides (HDPs) with anticancer activity. Maximin H5 is a C-terminally amidated, anionic host defence peptide (MH5N) from toads of the Bombina genus, which was shown to possess activity against the glioma cell line, T98G (EC50 = 125 μM). The peptide adopted high levels of α-helical structure (57.3%) in the presence of model cancer membranes (DMPC:DMPS in a molar ratio of 10:1). MH5N also showed a strong ability to penetrate these model membranes (Π = 10...
February 26, 2017: Biochimie
https://www.readbyqxmd.com/read/28231507/the-phytochelatin-synthase-gene-in-date-palm-phoenix-dactylifera-l-phylogeny-evolution-and-expression
#17
Chaâbene Zayneb, Rekik Hakim Imen, Kriaa Walid, C Douglas Grubb, Khemakhem Bassem, Vandenbulcke Franck, Mejdoub Hafedh, Elleuch Amine
We studied date palm phytochelatin synthase type I (PdPCS1), which catalyzes the cytosolic synthesis of phytochelatins (PCs), a heavy metal binding protein, in plant cells. The gene encoding PdPCS1 (Pdpcs) consists of 8 exons and 7 introns and encodes a protein of 528 amino acids. PCs gene history was studied using Notung phylogeny. During evolution, gene loss from several lineages was predicted including Proteobacteria, Bilateria and Brassicaceae. In addition, eleven gene duplication events appeared toward interior nodes of the reconciled tree and four gene duplication events appeared toward the external nodes...
February 20, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28222973/nationwide-multi-institutional-retrospective-analysis-of-high-dose-rate-brachytherapy-combined-with-external-beam-radiotherapy-for-localized-prostate-cancer-an-asian-prostate-hdr-bt-consortium
#18
Hiromichi Ishiyama, Nobuhiko Kamitani, Hidemasa Kawamura, Shingo Kato, Manabu Aoki, Shinji Kariya, Taisei Matsumura, Motoki Kaidu, Ken Yoshida, Yaichiro Hashimoto, Yasutaka Noda, Keith H C Lim, Takatsugu Kawase, Takeo Takahashi, Koji Inaba, Motoyasu Kumano, Nobuhiko Yoshikawa, Yasuo Yoshioka, Katsumasa Nakamura, Junichi Hiratsuka, Jun Itami, Kazushige Hayakawa
PURPOSE: To report outcomes and risk factors of high-dose-rate (HDR) brachytherapy combined with external beam radiotherapy with or without androgen deprivation therapy (ADT) in prostate cancer patients. MATERIALS AND METHODS: This multi-institutional retrospective analysis comprised 3424 patients with localized prostate cancer at 16 Asian hospitals. One-thirds (27.7%) of patients received only neoadjuvant ADT, whereas almost half (49.5%) of patients received both neoadjuvant and adjuvant ADT...
February 17, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28210041/underwater-treadmill-training-and-gait-ability-in-the-normal-adult
#19
Myoung-Kwon Kim, Si-A Lee
[Purpose] Our working hypothesis is that underwater treadmill training improves normal people's gait ability. [Subjects and Methods] Twenty-five healthy subjects with no orthopedic history of lower extremity were recruited. Gait training is performed using an underwater treadmill (HydroTrack(®) Underwater Treadmill System, Conray, Inc., Phoenix, AZ, USA), for twenty minutes per session, five sessions a week for four weeks. The water temperature was set at about 33 °C and the depth was fixed to reach between the subjects' xiphoid process and the navel...
January 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28209912/detection-efficacy-of-hybrid-68-ga-psma-ligand-pet-ct-in-prostate-cancer-patients-with-biochemical-recurrence-after-primary-radiation-therapy-defined-by-phoenix-criteria
#20
Ingo Einspieler, Isabel Rauscher, Charlotte Düwel, Markus Krönke, Christoph Rischpler, Gregor Habl, Sabrina Dewes, Armin Ott, Hans-Jürgen Wester, Markus Schwaiger, Tobias Maurer, Matthias Eiber
The aim of this retrospective study was to evaluate the detection rate of Glu-NH-CO-NH-Lys-(Ahx)-[(68)Ga(HBED-CC)] ((68)Ga-PSMA ligand) positron emission tomography/computed tomography (PET/CT) in patients with biochemical recurrent prostate cancer (PC) defined by Phoenix criteria after external beam radiotherapy (EBRT) or brachytherapy as primary treatment. Methods: 118 patients were finally eligible for this retrospective analysis with a median prostate-specific antigen (PSA) of 6.4 ng/mL (range: 2.2-158...
February 16, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
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