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https://www.readbyqxmd.com/read/28231507/the-phytochelatin-synthase-gene-in-date-palm-phoenix-dactylifera-l-phylogeny-evolution-and-expression
#1
Chaâbene Zayneb, Rekik Hakim Imen, Kriaa Walid, C Douglas Grubb, Khemakhem Bassem, Vandenbulcke Franck, Mejdoub Hafedh, Elleuch Amine
We studied date palm phytochelatin synthase type I (PdPCS1), which catalyzes the cytosolic synthesis of phytochelatins (PCs), a heavy metal binding protein, in plant cells. The gene encoding PdPCS1 (Pdpcs) consists of 8 exons and 7 introns and encodes a protein of 528 amino acids. PCs gene history was studied using Notung phylogeny. During evolution, gene loss from several lineages was predicted including Proteobacteria, Bilateria and Brassicaceae. In addition, eleven gene duplication events appeared toward interior nodes of the reconciled tree and four gene duplication events appeared toward the external nodes...
February 20, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28222973/nationwide-multi-institutional-retrospective-analysis-of-high-dose-rate-brachytherapy-combined-with-external-beam-radiotherapy-for-localized-prostate-cancer-an-asian-prostate-hdr-bt-consortium
#2
Hiromichi Ishiyama, Nobuhiko Kamitani, Hidemasa Kawamura, Shingo Kato, Manabu Aoki, Shinji Kariya, Taisei Matsumura, Motoki Kaidu, Ken Yoshida, Yaichiro Hashimoto, Yasutaka Noda, Keith H C Lim, Takatsugu Kawase, Takeo Takahashi, Koji Inaba, Motoyasu Kumano, Nobuhiko Yoshikawa, Yasuo Yoshioka, Katsumasa Nakamura, Junichi Hiratsuka, Jun Itami, Kazushige Hayakawa
PURPOSE: To report outcomes and risk factors of high-dose-rate (HDR) brachytherapy combined with external beam radiotherapy with or without androgen deprivation therapy (ADT) in prostate cancer patients. MATERIALS AND METHODS: This multi-institutional retrospective analysis comprised 3424 patients with localized prostate cancer at 16 Asian hospitals. One-thirds (27.7%) of patients received only neoadjuvant ADT, whereas almost half (49.5%) of patients received both neoadjuvant and adjuvant ADT...
February 17, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28210041/underwater-treadmill-training-and-gait-ability-in-the-normal-adult
#3
Myoung-Kwon Kim, Si-A Lee
[Purpose] Our working hypothesis is that underwater treadmill training improves normal people's gait ability. [Subjects and Methods] Twenty-five healthy subjects with no orthopedic history of lower extremity were recruited. Gait training is performed using an underwater treadmill (HydroTrack(®) Underwater Treadmill System, Conray, Inc., Phoenix, AZ, USA), for twenty minutes per session, five sessions a week for four weeks. The water temperature was set at about 33 °C and the depth was fixed to reach between the subjects' xiphoid process and the navel...
January 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28209912/detection-efficacy-of-hybrid-68-ga-psma-ligand-pet-ct-in-prostate-cancer-patients-with-biochemical-recurrence-after-primary-radiation-therapy-defined-by-phoenix-criteria
#4
Ingo Einspieler, Isabel Rauscher, Charlotte Düwel, Markus Krönke, Christoph Rischpler, Gregor Habl, Sabrina Dewes, Armin Ott, Hans-Jürgen Wester, Markus Schwaiger, Tobias Maurer, Matthias Eiber
The aim of this retrospective study was to evaluate the detection rate of Glu-NH-CO-NH-Lys-(Ahx)-[(68)Ga(HBED-CC)] ((68)Ga-PSMA ligand) positron emission tomography/computed tomography (PET/CT) in patients with biochemical recurrent prostate cancer (PC) defined by Phoenix criteria after external beam radiotherapy (EBRT) or brachytherapy as primary treatment. Methods: 118 patients were finally eligible for this retrospective analysis with a median prostate-specific antigen (PSA) of 6.4 ng/mL (range: 2.2-158...
February 16, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28195685/stigmatization-among-people-living-with-hiv-in-hong-kong-a%C3%A2-qualitative-study
#5
Phoenix K H Mo, Charlson T Y Ng
BACKGROUND: HIV/AIDS is one of the most stigmatized medical conditions across the world. Self-stigma is prevalent among people living with HIV (PLHIV) and a major obstacle to HIV prevention and care. OBJECTIVE: This study aimed to describe the experiences of stigmatization and explore the possible factors that might be associated with stigmatization among PLHIV in Hong Kong. DESIGN: Qualitative in-depth interviews were conducted. SETTING AND PARTICIPANTS: 15 PLHIV were recruited from two local non-governmental organizations on HIV prevention...
February 14, 2017: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/28189062/batch-and-fixed-bed-adsorption-of-levofloxacin-on-granular-activated-carbon-from-date-phoenix-dactylifera-l-stones-by-koh-chemical-activation
#6
Teeba M Darweesh, Muthanna J Ahmed
Granular activated carbon (KAC) was prepared from abundant Phoenix dactylifera L. stones by microwave- assisted KOH activation. The characteristics of KAC were tested by pore analyses, scanning electron microscopy (SEM) and Fourier transforms infrared spectroscopy (FTIR). The adsorption behavior of levofloxacin (LEV) antibiotic on KAC with surface area of 817m(2)/g and pore volume of 0.638cm(3)/g were analyzed using batch and fixed bed systems. The equilibrium data collected by batch experiments were well fitted with Langmuir compared to Freundlich and Temkin isotherms...
February 5, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28167552/pharmacokinetic-of-benznidazole-in-healthy-volunteers-implications-in-future-clinical-trials
#7
I Molina, F Salvador, A Sánchez-Montalvá, M A Artaza, R Moreno, L Perin, A Esquisabel, L Pinto, J L Pedraz
BACKGROUND: Despite its toxicity and low efficacy in the chronic phase, benznidazole is the drug of choice in Chagas disease. Scarce information about pharmacokinetics and pharmacodynamics of benznidazole has been published. METHODS: We performed a phase I, open-label, non-randomized pharmacokinetic study of benznidazole (Abarax®) conducted in 8 healthy adult volunteers at the Infectious Diseases Department of the Vall d'Hebron University Hospital (Barcelona, Spain)...
February 6, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28167450/extraction-optimization-and-in-vitro-and-in-vivo-anti-postprandial-hyperglycemia-effects-of-inhibitor-from-phoenix-dactylifera-l-parthenocarpic-fruit
#8
Hanen El Abed, Mouna Chakroun, Imen Fendri, Mohamed Makni, Mohamed Bouaziz, Noureddine Drira, Hafedh Mejdoub, Bassem Khemakhem
Phoenix dactylifera L. plays an important role in social, economic, and ecological Tunisian sectors. Some date palms produce parthenocarpic fruit named Sish. The aqueous ethanolic extract from P. dactylifera parthenocarpic dates demonstrated a potent inhibition of the enzymes related to type II diabetes. In this work, extraction optimization of amylase inhibitors was carried out using Box-Behnken Design. Bioactivity-guided fractionation of the 70% aqueous ethanol extract was performed to identify the active compounds...
February 3, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28167440/application-of-optimized-large-surface-area-date-stone-phoenix-dactylifera-activated-carbon-for-rhodamin-b-removal-from-aqueous-solution-box-behnken-design-approach
#9
Mohammed Danish, Waheed Ahmad Khanday, Rokiah Hashim, Nurul Syuhada Binti Sulaiman, Mohammad Nishat Akhtar, Maniruddin Nizami
Box-Behnken model of response surface methodology was used to study the effect of adsorption process parameters for Rhodamine B (RhB) removal from aqueous solution through optimized large surface area date stone activated carbon. The set experiments with three input parameters such as time (10-600min), adsorbent dosage (0.5-10g/L) and temperature (25-50°C) were considered for statistical significance. The adequate relation was found between the input variables and response (removal percentage of RhB) and Fisher values (F- values) along with P-values suggesting the significance of various term coefficients...
February 3, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28152251/diffusion-weighted-mri-treatment-monitoring-of-primary-hypofractionated-proton-and-carbon-ion-prostate-cancer-irradiation-using-raster-scan-technique
#10
Maya B Wolf, Christopher Edler, Diana Tichy, Matthias C Röthke, Heinz-Peter Schlemmer, Klaus Herfarth, David Bonekamp
PURPOSE: To investigate parametric changes in the apparent diffusion coefficient (ADC) at multiple timepoints during and after completion of primary proton and carbon ion irradiation of prostate cancer (PCa) as compared with normal-appearing prostate parenchyma. MATERIALS AND METHODS: In all, 92 patients with histologically confirmed PCa received either proton or carbon ion hypofractionated radiotherapy (RT). All were prospectively evaluated with diffusion-weighted magnetic resonance imaging (DWI-MRI) at five timepoints: baseline, day 10 during therapy and 6 weeks, 6 months, and 18 months after treatment...
February 2, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28143764/prostate-specific-antigen-density-is-predictive-of-outcome-in-suboptimal-prostate-seed-brachytherapy
#11
David Benzaquen, Guila Delouya, Cynthia Ménard, Maroie Barkati, Daniel Taussky
PURPOSE: In prostate seed brachytherapy, a D90 of <130 Gy is an accepted predictive factor for biochemical failure (BF). We studied whether there is a subpopulation that does not need additional treatment after a suboptimal permanent seed brachytherapy implantation. METHODS AND MATERIALS: A total of 486 patients who had either BF or a minimum followup of 48 months without BF were identified. BF was defined according to the Phoenix definition (nadir prostate-specific antigen + 2)...
January 28, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28143437/synchronicity-of-influenza-activity-within-phoenix-az-during-the-2015-2016-seasonal-epidemic
#12
James Tamerius, Jhobe Steadman, John Tamerius
BACKGROUND: Variability in the timing of influenza epidemics has been observed across global and regional scales, but this variability has not been studied extensively at finer spatial scales. As such, the aim of this study was to test whether influenza cases were synchronized across sites and/or age-groups within a major city. METHODS: We used influenza cases identified by rapid influenza tests from a network of clinics across Phoenix, AZ during the 2015-2016 influenza A season...
January 31, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28134339/dietary-fatty-acid-metabolism-of-brown-adipose-tissue-in-cold-acclimated-men
#13
Denis P Blondin, Hans C Tingelstad, Christophe Noll, Frédérique Frisch, Serge Phoenix, Brigitte Guérin, Éric E Turcotte, Denis Richard, François Haman, André C Carpentier
In rodents, brown adipose tissue (BAT) plays an important role in producing heat to defend against the cold and can metabolize large amounts of dietary fatty acids (DFA). The role of BAT in DFA metabolism in humans is unknown. Here we show that mild cold stimulation (18 °C) results in a significantly greater fractional DFA extraction by BAT relative to skeletal muscle and white adipose tissue in non-cold-acclimated men given a standard liquid meal containing the long-chain fatty acid PET tracer, 14(R,S)-[(18)F]-fluoro-6-thia-heptadecanoic acid ((18)FTHA)...
January 30, 2017: Nature Communications
https://www.readbyqxmd.com/read/28133845/determination-of-cloxacillin-residues-in-dairy-cows-after-intramammary-administration
#14
A Burmańczuk, T Grabowski, M Osypiuk, B Polska, C Kowalski
The aim of this study was to perform a comparative analysis of the characteristics of cloxacillin (CLO) (MRL of withdrawal in bovine milk is 30 ng/g) after a single intramammary (IMM) dose in the dry period (DP) and lactation (LP), and to establish a high-performance liquid chromatography (HPLC) analytical method for CLO detection in milk. The research was conducted on a group of 10 cows in DP and 10 in LP. A single dose of 600 mg of CLO was administrated by the IMM route for a single quarter in DP and 500 mg for a single quarter in LP...
January 30, 2017: Journal of Veterinary Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28124968/-accurate-diagnosis-of-pseudomonas-luteola-in-routine-microbiology-laboratory-on-the-occasion-of-two-isolates
#15
Muharrem Çiçek, Gülşen Hasçelik, H Kaan Müştak, K Serdar Diker, Burçin Şener
Pseudomonas luteola which was previously known as Chryseomonas luteola; is a gram-negative, non-fermentative, aerobic, motile, non-spore-forming bacillus. It is frequently found as a saprophyte in soil, water and other damp environments and is an opportunistic pathogen in patients with underlying medical disorders or with indwelling catheters. It has been reported as an uncommon cause of bacteremia, sepsis, septic arthritis, meningitis, endocarditis, and peritonitis. Thus, early and accurate identification of this rare species is important for the treatment and also to provide information about the epidemiology of P...
October 2016: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28121536/aca-phoenix-of-or-cooked-in-this-dumpster-fire-of-an-election
#16
Richard Mark Kirkner
Hillary Clinton and Donald Trump promise divergent approaches to the ACA if elected. Basically, Clinton wants to improve it; Trump promises to dismantle it. Of course, no president acts in a vacuum, and a lot will also depend on which party controls Congress.
October 2016: Managed Care
https://www.readbyqxmd.com/read/28107793/does-violence-in-adolescence-differentially-predict-offending-patterns-in-early-adulthood
#17
Stephanie M Cardwell, Alex R Piquero
Previous research is mixed on whether the commission of a violent offense in adolescence is predictive of criminal career characteristics. In the current study, we addressed the following: (a) What factors predict the commission of serious violence in mid-adolescence? and (b) Does involvement in serious violence in mid-adolescence lead to more chronic and/or more heterogeneous patterns of offending in early adulthood? Data were obtained from the Pathways to Desistance Study, a longitudinal study of serious adolescent offenders in Philadelphia, Pennsylvania, and Phoenix, Arizona...
January 1, 2017: International Journal of Offender Therapy and Comparative Criminology
https://www.readbyqxmd.com/read/28106678/the-influence-of-emerging-nursing-administrative-and-leadership-researchers-an-interview-with-dr-lesly-kelly
#18
Jeffrey M Adams
This department highlights emerging nursing leaders who have demonstrated leadership in advancing innovation and patient care in practice, policy, research, education, and theory. This interview profiles Lesly Kelly, PhD, RN, Assistant Professor at the Arizona State University College of Nursing and Health Innovation and Nursing and Clinical Research Program Director at Banner-University Medical Center Phoenix.
February 2017: Journal of Nursing Administration
https://www.readbyqxmd.com/read/28099675/a-newly-licensed-nurse-orientation-program-evaluation-focus-on-outcomes
#19
Nancy Phoenix Bittner, Gayle Gravlin, Claire MacDonald, Darlene Bourgeois
The aim of this project was to evaluate the effectiveness and outcomes of a redesigned newly licensed nurse orientation program. A unique aspect of this program was an end-of-orientation simulated four-patient assignment that was designed to assess five categories of critical thinking: prioritization and delegation, problem recognition, clinical decision making, clinical implementation, and reflection. Newly licensed nurses' critical thinking was measured by the Advisory Board's Critical Thinking Diagnostic tool at 10 weeks, 6 months, and 12 months...
January 1, 2017: Journal of Continuing Education in Nursing
https://www.readbyqxmd.com/read/28094903/evaluation-of-the-efficacy-of-insecticidal-coatings-based-on-teflutrin-and-chlorpyrifos-against-rhynchophorus-ferrugineus
#20
Massimo Pugliese, Alberto Rettori Andrea, Roberto Martinis, Khalid Al-Rohily, Velate Suresh, Moideen Mohamed Ashraf, Ali Al-Maashi
BACKGROUND: The date palm (Phoenix dactylifera L.) is an important economic resource for many nations worldwide, recently threatened by the presence of different insect pests, like the red palm weevil (RPW) Rhynchophorus ferrugineus. RESULTS: Two products, a glue (polyvinyl acetate) and an oil (raw linseed oil), have been used as coatings and applied together with a repellent and two insecticides (teflutrin and chlorpyrifos) at different dosages on 2 species of palm (Phoenix dactylifera and Phoenix canariensis)...
January 17, 2017: Pest Management Science
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