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Urolithiasis

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https://www.readbyqxmd.com/read/29449591/familial-risks-between-urolithiasis-and-cancer
#1
Kari Hemminki, Otto Hemminki, Asta Försti, Jan Sundquist, Kristina Sundquist, Xinjun Li
Urolithiasis (UL, urinary tract stone disease) has been reported to increase subsequent cancers in the urinary tract. Recently, we showed data that surveillance bias may be an important confounder in the reported associations. In the present approach we want to address the question of possible cancer risk posed by UL mechanistically. Both UL and cancer have strong genetic components and we hypothesize that familial association between UL and cancer may be plausible. We thus assess familial risks between UL and cancer, hoping to find an explanation why UL may pose a risk of cancer...
February 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29444590/-stone-trees-metabolic-evaluation-and-medical-treatment-of-the-urolithiasis-patient-made-easy
#2
Ralph V Clayman, Roshan M Patel, Margaret S Pearle
In this review, a simplified straightforward algorithmic approach to the metabolic evaluation and treatment of the at-risk or recurrent urolithiasis patient is provided. Eight diagnoses and eight therapies are provided which cover over 95% of renal stone disease.
February 14, 2018: Journal of Endourology
https://www.readbyqxmd.com/read/29443696/intravenous-lidocaine-for-intractable-renal-colic-unresponsive-to-standard-therapy
#3
Billy Sin, John Cao, David Yang, Karen Ambert, Sheena Punnapuzha
CLINICAL FEATURES: Renal colic is defined as a flank pain radiating to the groin caused by kidney stones in the ureter (urolithiasis). Renal colic is a frequent cause of Emergency Department visits. Most renal colic cases present as acute distress and severe back and/or abdominal pain that require prompt treatment with analgesics. THERAPEUTIC CHALLENGE: Nonsteroidal anti-inflammatory drugs and opioids are traditionally used for renal colic in the Emergency Department...
February 13, 2018: American Journal of Therapeutics
https://www.readbyqxmd.com/read/29432040/protective-roles-of-flavonoids-and-flavonoid-rich-plant-extracts-against-urolithiasis-a-review
#4
Xiangquan Zeng, Yu Xi, Weibo Jiang
In the urinary system, urolithiasis is the third prevalent disorder which causes severe pain in individuals. Urinary stones are composed of calcium oxalate (CaOx) and calcium phosphate in approximately 80% of patients. Although various drugs and surgery operations are used to treat the disease, side effects of drugs and the high recurrence after therapy in patients cannot be ignored. Flavonoids are a large group of plant polyphenols with presumed beneficial effects on several common diseases. Whereas, a very few have reached clinical use...
February 12, 2018: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/29424333/pathogenesis-of-proteus-mirabilis-infection
#5
Chelsie E Armbruster, Harry L T Mobley, Melanie M Pearson
Proteus mirabilis , a Gram-negative rod-shaped bacterium most noted for its swarming motility and urease activity, frequently causes catheter-associated urinary tract infections (CAUTIs) that are often polymicrobial. These infections may be accompanied by urolithiasis, the development of bladder or kidney stones due to alkalinization of urine from urease-catalyzed urea hydrolysis. Adherence of the bacterium to epithelial and catheter surfaces is mediated by 17 different fimbriae, most notably MR/P fimbriae...
February 2018: EcoSal Plus
https://www.readbyqxmd.com/read/29423725/the-impact-of-body-mass-index-on-quantitative-24-h-urine-chemistries-in-stone-forming-patients-a-systematic-review-and-meta-analysis
#6
Qing Wang, Weijie Hu, Yuchao Lu, Henglong Hu, Jiaqiao Zhang, Shaogang Wang
To study the impact of body mass index (BMI) on quantitative 24-h urine chemistries in stone forming patients and to explore how overweight and obesity contribute to urolithiasis. A systematic search of PubMed, EMBASE, Cochrane Library, and Web of Science was performed in July 2017 and updated in October 2017 to detect relevant studies. After that, we screened all the relevant articles in accordance with the predetermined inclusion and exclusion criteria. Data of eligible studies were extracted, and then, a meta-analysis was conducted via RevMan 5...
February 8, 2018: Urolithiasis
https://www.readbyqxmd.com/read/29421299/impact-of-statin-intake-on-kidney-stone-formation
#7
Andrew J Cohen, Melanie A Adamsky, Charles U Nottingham, Jaclyn Pruitt, Brittany Lapin, Chi H Wang, Sangtae Park
OBJECTIVES: To determine whether statin intake affects nephrolithiasis risk, and whether higher lipid levels correlate with stone risk. Dyslipidemia is a known independent risk factor for urolithiasis, and emerging evidence suggests common biological pathways. Previous work has suggested that statins protect against new stone formation, but these findings have not been verified by other investigators. METHODS: We queried our Institution's Electronic Data Warehouse for all patients who were newly diagnosed with hyperlipidemia between 2009 and 2011, and had never taken a statin drug...
February 5, 2018: Urology
https://www.readbyqxmd.com/read/29416283/metabolic-evaluation-of-children-with-urolithiasis
#8
Vijayabhaskar Reddy Gouru, Vedamurthy Reddy Pogula, Surya Prakash Vaddi, Venu Manne, Ranadheer Byram, Lalith Sagar Kadiyala
Aim: The aim of the study is to identify the prevalence of metabolic abnormalities in children with urolithiasis. Materials and Methods: This is a prospective study; all children below 15 years who are found to have urolithiasis were prospectively evaluated with relevant history, clinical examination, and urine and serum testing. Metabolic workup includes complete urine examination, urine culture and sensitivity, and 24-h urinary analysis (lithorisk profile). Results: A total of 55 patients are included in the study...
January 2018: Urology Annals
https://www.readbyqxmd.com/read/29411942/libs-raman-an-effective-complementary-approach-to-analyze-renal-calculi
#9
K M Muhammed Shameem, Arun Chawla, Madhukar Mallya, Bijay Kumar Barik, V K Unnikrishnan, V B Kartha, C Santhosh
Presence of renal calculi (kidney stones) in human urethra is being increasingly diagnosed over the last decade and is considered as one of the most painful urological disorders. Accurate analysis of such stones plays a vital role in the evaluation of urolithiasis patients and in turn helps the clinicians toward exact etiologies. Two highly complementary laser-based analytical techniques; Laser Induced Breakdown Spectroscopy (LIBS) and micro-Raman spectroscopy have been used to identify the chemical composition of different types of renal calculi...
February 7, 2018: Journal of Biophotonics
https://www.readbyqxmd.com/read/29406799/management-of-pediatric-urolithiasis-using-a-combination-of-laparoscopic-lithotomy-and-pyeloscopy
#10
Sergio Landa-Juárez, Bárbara M Rivera-Pereira, Ana M Castillo-Fernández
BACKGROUND: Minimally invasive procedures have become the standard option for treatment of urinary stones; the use of more invasive techniques is not a common practice currently. This emergent technology is not always available and laparoscopy is the alternative option. There are few reports of laparoscopic management for urinary lithiasis in pediatric patients. This study is about the use of laparoscopic surgery combined with pyeloscopy as a feasible first-line treatment for pediatric urolithiasis in renal and proximal ureteral locations...
February 6, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29406057/urinary-stone-disease-diagnosis-medical-therapy-and-surgical-management
#11
REVIEW
Wesley W Ludwig, Brian R Matlaga
Clinical suspicion of urolithiasis should be evaluated with low-dose computed tomography as the first-line imaging modality for nonpregnant, adult patients. A period of observation may be appropriate for ureteral stones less than 10 mm, and medical expulsive therapy may be beneficial for facilitating passage of distal ureteral stones. Regardless of stone type, patients should adhere to a low-sodium diet and attempt to achieve a urine volume of more than 2.5 L daily. Individuals with calcium stones should maintain a normal calcium diet, and if stones persist, citrate therapy or thiazide diuretics in the setting of hypercalciuria may be indicated...
March 2018: Medical Clinics of North America
https://www.readbyqxmd.com/read/29400579/occult-urolithiasis-in-asymptomatic-primary-hyperparathyroidism
#12
Yu-Kwang Donovan Tay, Minghao Liu, Leonardo Bandeira, Mariana Bucovsky, James A Lee, Shonni J Silverberg, Marcella D Walker
OBJECTIVE: Recent international guidelines suggest renal imaging to detect occult urolithiasis in all patients with asymptomatic primary hyperparathyroidism (PHPT), but data regarding their prevalence and associated risk factors are limited. We evaluated the prevalence and risk factors for occult urolithiasis. METHODS: Cross-sectional analysis of 96 asymptomatic PHPT patients from a university hospital in the United States with and without occult nephrolithiasis...
February 5, 2018: Endocrine Research
https://www.readbyqxmd.com/read/29399302/laser-application-in-iran-urology-a-narrative-review
#13
REVIEW
Mohammad Reza Razzaghi, Morteza Fallah Karkan, Saleh Ghiasy, Babak Javanmard
The usage of laser in medicine is not recent, and its history in urology goes back to 40 years ago. For the last 2 decades, common uses of laser have been treatments of subjects with urolithiasis, bladder tumors, benign prostatic enlargement, lesions of the genitalia and urinary tract strictures. To evaluate laser application in urology in Iran, we reviewed all of the Iranian literature on the topic. This study was designed to retrieve all studies on laser application in urology in Iran, regardless of publication status or language, covering years 1990-2017...
2018: Journal of Lasers in Medical Sciences
https://www.readbyqxmd.com/read/29389928/review-of-acute-symptomatic-urolithiasis-in-auckland
#14
Stephanie Loeff, Manmeet Saluja, Michael Rice
AIM: To evaluate the incidence of acute symptomatic urolithiasis in the Auckland region. Associated epidemiological factors and stone characteristics were also studied and compared to previous research conducted in order to analyse trends. METHOD: All patients that presented acutely with symptomatic urolithiasis to the Auckland District Health Board (AHDB) between July 2014 and June 2015 were studied. Clinical data was obtained from medical records and population data was based on estimates provided by the Ministry of Health...
February 2, 2018: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29386681/struvite-urolithiasis-with-eosinophilic-polypoid-cystitis-in-a-shih-tzu-dog
#15
Meagan A Walker
A 7-year-old female spayed shih tzu dog was presented with hematuria of 4 weeks' duration. Radiographs revealed 1 cystic calculus. A polypoid mass was found incidentally during cystotomy and was removed by partial cystectomy. Histopathology revealed eosinophilic polypoid cystitis and urolith analysis reported struvite. A urinary tract infection was treated.
February 2018: Canadian Veterinary Journal. la Revue Vétérinaire Canadienne
https://www.readbyqxmd.com/read/29376594/-clinical-and-biochemical-aspects-of-pathogenesis-of-urolithiasis
#16
Z A Kadyrov, S I Suleymanov, V Sh Ramishvili, V G Istratov
AIM: To investigate the role of infection in the pathogenesis of urolithiasis using chromatography mass spectrometry analysis. MATERIALS AND METHODS: The study analyzed clinical and laboratory data of 316 urolithiasis patients hospitalized between February 2005 and January 2015. All patients underwent a comprehensive clinical examination, including laboratory tests (hematological and biochemical blood tests, clinical and bacteriological tests of urine) and chromatography mass spectrometry analysis urine and blood...
December 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/29371637/cell-death-based-approaches-in-treatment-of-the-urinary-tract-associated-diseases-a-fight-for-survival-in-the-killing-fields
#17
REVIEW
Diego Martin-Sanchez, Miguel Fontecha-Barriuso, Maria Dolores Sanchez-Niño, Adrian M Ramos, Ramiro Cabello, Carmen Gonzalez-Enguita, Andreas Linkermann, Ana Belén Sanz, Alberto Ortiz
Urinary tract-associated diseases comprise a complex set of disorders with a variety of etiologic agents and therapeutic approaches and a huge global burden of disease, estimated at around 1 million deaths per year. These diseases include cancer (mainly prostate, renal, and bladder), urinary tract infections, and urolithiasis. Cell death plays a key role in the pathogenesis and therapy of these conditions. During urinary tract infections, invading bacteria may either promote or prevent host cell death by interfering with cell death pathways...
January 25, 2018: Cell Death & Disease
https://www.readbyqxmd.com/read/29368300/hyperuricosuric-calcium-urolithiasis
#18
REVIEW
Orson W Moe, Li Hao Richie Xu
Hyperuricosuric calcium urolithiasis is a condition of mixed calcium oxalate stones characterized by hyperuricosuria either in isolation or in conjunction with other risk factors for calcium oxalate stones such as hypercalciuria, hyperoxaluria, and hypocitraturia. There are three proposed physicochemical models of pathogenesis where urate in its crystalline phase via heterogeneous nucleation, in its colloidal phase via removal of crystallization inhibitors, and in solution via precipitation crystallization, can all increase propensity to calcium oxalate precipitation...
January 24, 2018: Journal of Nephrology
https://www.readbyqxmd.com/read/29364722/low-dose-ct-for-evaluation-of-suspected-urolithiasis-diagnostic-yield-for-assessment-of-alternative-diagnoses
#19
Julius Matthias Weinrich, Peter Bannas, Marc Regier, Sarah Keller, Luis Kluth, Gerhard Adam, Frank Oliver Henes
OBJECTIVE: The purpose of this study is to assess the diagnostic yield of low-dose (LD) CT for alternative diagnoses in patients with suspected urolithiasis. MATERIALS AND METHODS: In this retrospective study, we included 776 consecutive patients who underwent unenhanced abdominal CT for evaluation of suspected urolithiasis. All examinations were performed with an LD CT protocol; images were reconstructed using iterative reconstruction. The leading LD CT diagnosis was recorded for each patient and compared with the final clinical diagnosis, which served as the reference standard...
January 24, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29364405/-antiurolithic-activity-of-the-ethanolic-extract-of-ayacuchano-propolis-in-rats
#20
Rita López-Cabanillas, Ronal Huayanay-Conde, Cinthya Gonzales, Mahli Maguiña, Italo Granados, Mila Ccasani, Astrid Laguna, Ernesto León, Nuria Romero-Caballero, Jessenia Chacón
OBJECTIVES: To determine the antiurolytic activity of the ethanolic extract of Ayacuchan propolis in a preventive model of urolithiasis in rats. MATERIALS AND METHODS: A total of 45 male Sprague-Dawley albino rats were studied. The antiurolithic effect was analyzed in five groups of six animals each: blank, control (treated with 1 mL of 5% ethylene glycol and 1 mL of 5% ammonium chloride), and three experimental groups (treated with the ethanol extract of propolis at a daily dose of 250, 350, and 500 mg/kg, respectively)...
October 2017: Revista Peruana de Medicina Experimental y Salud Pública
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