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Pericardial FAT

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https://www.readbyqxmd.com/read/27856485/ectopic-fat-depots-and-coronary-artery-calcium-in-south-asians-compared-with-other-racial-ethnic-groups
#1
Sachin K Garg, Feng Lin, Namratha Kandula, Jingzhong Ding, Jeffrey Carr, Matthew Allison, Kiang Liu, David Herrington, Dhananjay Vaidya, Eric Vittinghoff, Alka M Kanaya
BACKGROUND: South Asians have a low body mass index and high prevalence of cardiovascular disease (CVD) relative to other racial/ethnic groups. Radiographically detected ectopic fat distribution is better associated with CVD than body mass index. We assessed whether differences in ectopic fat depots explained differences in the prevalence/severity of coronary artery calcium (CAC), a predictor of incident CVD events, among South Asians compared with other racial/ethnic groups. METHODS AND RESULTS: We examined the associations of radiographically detected visceral, intermuscular, intrahepatic, and pericardial fat with CAC among adults without baseline CVD...
November 17, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27806176/abrupt-onset-of-refractory-heart-failure-associated-with-light-chain-amyloidosis-in-hypertrophic-cardiomyopathy
#2
Benedetta Tomberli, Francesco Cappelli, Federico Perfetto, Iacopo Olivotto
Importance: The natural history of hypertrophic cardiomyopathy (HCM) is complex and may include progressive heart failure and severe left ventricular dysfunction. When disease progression is abrupt, however, other coexisting diseases should be ruled out. This may be difficult in the case of amyloidosis, which classically mimics HCM. Results: We present an example of severe clinical deterioration in a patient with HCM due to superimposed amyloid light-chain amyloidosis...
November 2, 2016: JAMA Cardiology
https://www.readbyqxmd.com/read/27790354/assosiation-of-epicardial-and-pericardial-fat-thickness-with-coronary-artery-disease
#3
Fereshteh Ghaderi, Ali Eshraghi, Alireza Sepehri Shamloo, Sareh Mousavi
INTRODUCTION: Visceral adipose tissue is a known important risk factor for coronary artery disease (CAD). While some studies have suggested relationship between epicardial fat thickness (EFT) and CAD, there are no adequate studies for pericardial fat thickness (PFT). The aim of this study was to determine the association of EFT and PFT with CAD. METHODS: This cross-sectional study was conducted on patients who were candidates for elective coronary artery angiography, referred to Emam Reza Hospital, Mashhad, Iran during Jan 2014-2016...
September 2016: Electronic Physician
https://www.readbyqxmd.com/read/27783380/common-pitfalls-in-point-of-care-ultrasound-a-practical-guide-for-emergency-and-critical-care-physicians
#4
REVIEW
Pablo Blanco, Giovanni Volpicelli
BACKGROUND: Point-of-care ultrasonography (POCUS) is a widely used tool in emergency and critical care settings, useful in the decision-making process as well as in interventional guidance. While having an impressive diagnostic accuracy in the hands of highly skilled operators, inexperienced practitioners must be aware of some common misinterpretations that may lead to wrong decisions at the bedside. OBJECTIVES: This article provides a revision list of common POCUS misdiagnoses usually found in practice and offers useful tips to recognize and avoid them...
December 2016: Critical Ultrasound Journal
https://www.readbyqxmd.com/read/27699898/adipose-tissue-regulates-insulin-sensitivity-role-of-adipogenesis-de-novo-lipogenesis-and-novel-lipids
#5
U Smith, B B Kahn
Obesity, the major cause of the current global epidemic of type 2 diabetes (T2D), induces insulin resistance in peripheral insulin target tissues. Several mechanisms have been identified related to cross-talk between adipose tissue, skeletal muscle and liver. These mechanisms involve both increased free fatty acid release and altered secretion of adipokines from adipose tissue. A major determinant of metabolic health is the ability of subcutaneous adipose tissue (SAT) to store excess fat rather than allowing it to accumulate in ectopic depots including liver (i...
November 2016: Journal of Internal Medicine
https://www.readbyqxmd.com/read/27666172/relation-of-pericardial-fat-intrathoracic-fat-and-abdominal-visceral-fat-with-incident-atrial-fibrillation-from-the-framingham-heart-study
#6
Jane J Lee, Xiaoyan Yin, Udo Hoffmann, Caroline S Fox, Emelia J Benjamin
Obesity is associated with increased risk of developing atrial fibrillation (AF). Different fat depots may have differential associations with cardiac pathology. We examined the longitudinal associations between pericardial, intrathoracic, and visceral fat with incident AF. We studied Framingham Heart Study Offspring and Third-Generation Cohorts who participated in the multidetector computed tomography substudy examination 1. We constructed multivariable-adjusted Cox proportional hazard models for risk of incident AF...
November 15, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27621828/association-between-adiposity-and-systemic-atherosclerosis-a-protocol-of-a-cross-sectional-autopsy-study
#7
Aline Nishizawa, Claudia Kimie Suemoto, Daniela Souza Farias, Fernanda Marinho Campos, Karen Cristina Souza da Silva, Anderson Cuelho, Renata Elaine Paraízo Leite, Renata Eloah de Lucena Ferretti-Rebustini, Lea Tenenholz Grinberg, José Marcelo Farfel, Wilson Jacob-Filho, Carlos Augusto Pasqualucci
INTRODUCTION: Adiposity has been associated with atherosclerosis in clinical studies. However, few autopsy studies have investigated this association, and they had only examined the coronary artery disease. Moreover, most studies had small sample sizes and were limited to middle-aged or young adults. Our aim is to investigate the association between adiposity and systemic atherosclerosis in an autopsy study. METHODS AND ANALYSIS: A sample of 240 deceased with 30 years or more will be evaluated...
2016: Open Heart
https://www.readbyqxmd.com/read/27606110/impact-of-body-mass-index-on-vascular-calcification-and-pericardial-fat-volume-among-patients-with-suspected-coronary-artery-disease
#8
Hussein Nafakhi, Abdulameer Al-Mosawi, Hayder Elwali, Hasan Al-Nafakh, Raad Tawfeq, Ahmed Nafakhi
OBJECTIVES: This study aimed to assess the effect of body mass index (BMI) on the relationship between pericardial fat volume (PFV), aortic root calcification (ARC) and coronary artery calcification (CAC) among patients with suspected coronary artery disease (CAD). METHODS: This cross-sectional study took place between January and December 2014 at the Kufa University Teaching Hospital, Najaf, Iraq. A total of 130 consecutive patients with an intermediate pretest probability of ischaemic heart disease who underwent 64-slice multidetector computed tomography (CT) angiography during the study period were recruited...
August 2016: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/27582256/fat-associated-lymphoid-clusters-control-local-igm-secretion-during-pleural-infection-and-lung-inflammation
#9
Lucy H Jackson-Jones, Sheelagh M Duncan, Marlène S Magalhaes, Sharon M Campbell, Rick M Maizels, Henry J McSorley, Judith E Allen, Cécile Bénézech
Fat-associated lymphoid clusters (FALC) are inducible structures that support rapid innate-like B-cell immune responses in the serous cavities. Little is known about the physiological cues that activate FALCs in the pleural cavity and more generally the mechanisms controlling B-cell activation in FALCs. Here we show, using separate models of pleural nematode infection with Litomosoides sigmodontis and Altenaria alternata induced acute lung inflammation, that inflammation of the pleural cavity rapidly activates mediastinal and pericardial FALCs...
2016: Nature Communications
https://www.readbyqxmd.com/read/27528109/pericardial-adipose-tissue-and-the-metabolic-syndrome-is-increased-in-patients-with-chronic-major-depressive-disorder-compared-to-acute-depression-and-controls
#10
K G Kahl, J Herrmann, B Stubbs, T H C Krüger, J Cordes, M Deuschle, U Schweiger, K Hüper, S Helm, A Birkenstock, D Hartung
OBJECTIVE: Major depressive disorder (MDD) is associated with an estimated fourfold risk for premature death, largely attributed to cardiovascular disorders. Pericardial adipose tissue (PAT), a fat compartment surrounding the heart, has been implicated in the development of coronary artery disease. An unanswered question is whether people with chronic MDD are more likely to have elevated PAT volumes versus acute MDD and controls (CTRL). METHODS: The study group consists of sixteen patients with chronic MDD, thirty-four patients with acute MDD, and twenty-five CTRL...
January 4, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/27456108/abnormal-peri-organ-or-intra-organ-fat-apifat-deposition-an-underestimated-predictor-of-vascular-risk
#11
Niki Katsiki, Vasilios G Athyros, Dimitri P Mikhailidis
Adipose tissue, a major endocrine organ, consists of brown and white adipocytes. Brown fatmay play a beneficialrole in cardiometabolic disordersBrown adipose tissue can also improve glucose and lipid metabolism. In contrast, the expansion of white adipose tissue has been related to obesity, type 2 diabetes mellitus and cardiovascular disease (CVD). Both the quantity and the quality of the white adipose tissue as well as its distribution may affect CVD risk. In this context, the link between adiposity and CVD risk is greater for visceral than subcutaneous fat...
July 22, 2016: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/27445520/acute-chest-pain-related-to-pericardial-fat-necrosis
#12
Gilbert R Ferretti, Dominique Rigaud
No abstract text is available yet for this article.
2016: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
https://www.readbyqxmd.com/read/27391045/the-associations-between-various-ectopic-visceral-adiposity-and-body-surface-electrocardiographic-alterations-potential-differences-between-local-and-remote-systemic-effects
#13
Po-Ching Chi, Shun-Chuan Chang, Chun-Ho Yun, Jen-Yuan Kuo, Chung-Lieh Hung, Charles Jia-Yin Hou, Chia-Yuan Liu, Fei-Shih Yang, Tung-Hsin Wu, Hiram G Bezerra, Hung-I Yeh
BACKGROUND: The associations between pericardial adiposity and altered atrial conduction had been demonstrated. However, data comparing differential effects of various body sites visceral adiposity on atrial and ventricular electrocardiographic alterations remains largely unknown. METHODS AND RESULTS: We assessed both peri-cardial fat (PCF) and peri-aortic visceral adiposity (TAT) using dedicated computed tomography (CT) software (Aquarius 3D Workstation, TeraRecon, San Mateo, CA, USA), with anthropometrics including body mass index (BMI) and biochemical data obtained...
2016: PloS One
https://www.readbyqxmd.com/read/27369846/pericardial-fat-volume-is-related-to-atherosclerotic-plaque-burden-rather-than-to-lesion-severity
#14
Gaston A Rodriguez-Granillo, Patricia Carrascosa, Alejandro Deviggiano, Carlos Capunay, Macarena C De Zan, Alejandro Goldsmit, Roxana Campisi
AIMS: We sought to explore the relationship between pericardial fat volume (PFV) and both coronary atherosclerosis (CA) extent and severity using coronary artery calcium score (CAC), computed tomography coronary angiography (CTCA), and invasive coronary angiography in patients at high to intermediate likelihood of coronary artery disease (CAD). METHODS AND RESULTS: Patients clinically referred to invasive angiography who underwent CTCA and CAC within 1 month before the procedure comprised the study population...
July 1, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/27338871/clinical-results-of-bronchial-stump-coverage-using-free-pericardial-fat-pad
#15
Katsunari Matsuoka, Naoko Imanishi, Tetsu Yamada, Takahisa Matsuoka, Shinjiro Nagai, Mitsuhiro Ueda, Yoshihiro Miyamoto
OBJECTIVES: Bronchial fistula is a severe complication after thoracic surgery. Although many methods of coverage using various autologous tissues including pedicled pericardial fat pad have been reported to be useful for the prevention of bronchial fistula, the ideal roles of these approaches and the coverage techniques yielding the best results still remain unclear. The clinical use of an autologous free fat graft has been reported in the various surgical fields including otolaryngology, orthopaedics and plastic surgery...
October 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/27336402/intramyocardial-adipose-derived-stem-cell-transplantation-increases-pericardial-fat-with-recovery-of-myocardial-function-after-acute-myocardial-infarction
#16
Jong-Ho Kim, Soon Jun Hong, Chi-Yeon Park, Jae Hyung Park, Seung-Cheol Choi, Sang-Keun Woo, Jung Woo Yu, Gi Jeong Cheon, Hyung Joon Joo, Do-Sun Lim
Intramyocardial injection of adipose-derived stem cells (ASC) with other cell types in acute myocardial infarction (AMI) animal models has consistently shown promising clinical regenerative capacities. We investigated the effects of intramyocardial injections of mouse ASC (mASC) with mouse endothelial cells (mEC) on left ventricular function and generation of pericardial fat in AMI rats. AMI rat models were created by ligating left anterior descending coronary artery and were randomly assigned into four groups: control (n = 10), mASC (n = 10), mEC (n = 10) and mASC+mEC (n = 10) via direct intramyocardial injections, and each rat received 1x106 cells around three peri-infarct areas...
2016: PloS One
https://www.readbyqxmd.com/read/27311062/pericardial-fat-and-right-ventricular-morphology-the-multi-ethnic-study-of-atherosclerosis-right-ventricle-study-mesa-rv
#17
David S Wenger, Steven M Kawut, Jingzhong Ding, David A Bluemke, Catherine L Hough, Richard A Kronmal, Joao A Lima, Peter J Leary
BACKGROUND: Pericardial fat has been implicated in the pathogenesis of obesity-related cardiovascular disease. Proposed mechanisms may be relevant in right heart failure, but relationships between pericardial fat and right ventricular (RV) morphology have not been explored. METHODS: The Multi-Ethnic Study of Atherosclerosis is a prospective cohort that enrolled participants without clinical cardiovascular disease. Pericardial fat was measured using computed tomography and RV parameters using cardiac MRI...
2016: PloS One
https://www.readbyqxmd.com/read/27310996/an-observational-study-of-the-association-among-interatrial-adiposity-by-computed-tomography-measure-insulin-resistance-and-left-atrial-electromechanical-disturbances-in-heart-failure
#18
Chung-Lieh Hung, Chun-Ho Yun, Yau-Huei Lai, Kuo-Tzu Sung, Hiram G Bezerra, Jen-Yuan Kuo, Charles Jia-Yin Hou, Tze-Fan Chao, Bernard E Bulwer, Hung-I Yeh, Shou-Chuan Shih, Shing-Jong Lin, Ricardo C Cury
Excessive visceral adiposity, hypothesized to be a key mediator in metabolic derangements, has recently been shown to exert toxic effects on cardiac structure and function. Data regarding the mechanistic link between regional adiposity, left atrial (LA) electromechanical remodeling, and heart failure with preserved ejection fraction (HFpEF) have been lacking.Various visceral adiposity measures, including pericardial fat (PCF), thoracic periaortic (TAT) fat, regional inter-atrial fat (IAF), and atrioventricular groove fat (AV Groove Fat), were assessed by multidetector computed tomography in 2 study cohorts (an annual health survey cohort and an outpatient cohort)...
June 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27301329/pericardial-fat-is-associated-with-the-risk-of-ventricular-arrhythmia-in-asian-patients
#19
Weng-Chio Tam, Yung-Kuo Lin, Wing-Pong Chan, Jen-Hung Huang, Ming-Hsiung Hsieh, Shih-Ann Chen, Yi-Jen Chen
BACKGROUND: Pericardial fat is correlated with the occurrence of atrial fibrillation or coronary atherosclerosis. However, the role of pericardial fat in ventricular arrhythmia remains unclear. METHODS AND RESULTS: Patients who had undergone dual-source computed tomography and 24-h Holter ECG were retrospectively enrolled. Quantification of the volume of pericardial fat surrounding the ventricles was analyzed using threshold attenuation of dual-source CT. The volume of pericardial fat was significantly different among those without ventricular premature beats (VPBs) in 24 h (n=28), those with occasional VPBs (n=54) and those with frequent VPBs (n=34) (12...
July 25, 2016: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/27250975/the-floating-cardiac-fat-pad-sign-of-occult-pneumothorax
#20
Claire Kaufman, S A Jamal Bokhari
Pneumothoraces are a possible sequela of chest trauma with potential morbidity and mortality if not recognized and treated promptly. A portable supine chest radiograph is frequently the first radiologic study performed in the setting of trauma. While large pneumothoraces can be readily recognized on these radiographs, smaller pneumothoraces are missed in up to 15 % of trauma patients. There are many radiographic signs of occult pneumothoraces, and we are presenting a new radiographic sign of occult pneumothorax...
August 2016: Emergency Radiology
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