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https://www.readbyqxmd.com/read/29678849/effects-of-adenovirus-mediated-vegf165-gene-therapy-on-myocardial-infarction
#1
Chao Wang, Boya Zhang, Yu Lin, Yang Dong
AIM: To evaluate the role of adenovirus-mediated transduction human VEGF isoform 165 via direct myocardial injection in rats with an occluded circumflex coronary artery, and the possible underlying mechanism. METHODS: Sprague-Dawley rats were induced myocardial infarction (MI) with ligation of the left coronary artery. Rats were randomly divided into 4 groups: 1) the sham group; 2) the MI group; 3) the NS (normal saline) group and 4) the VEGF group. Direct myocardial injection of 0...
March 2018: Annals of Clinical and Laboratory Science
https://www.readbyqxmd.com/read/29674733/the-use-of-dental-implants-cast-bars-and-sleeve-overdentures-in-oral-cancer-patients
#2
R Ali, A Al-Khayatt, C Barclay
Surgical resection of an oral tumour (and the associated free flap reconstruction) can significantly alter the oral anatomy. The lack of sulcus depth, alveolar ridge, presence of a mobile flap and limited tongue movement can make it impossible for patients to control a removable prosthesis. To help this cohort of patients, dental implants can be invaluable. The Oral Rehabilitation Team at Central Manchester University Dental Hospital have used dental implants to rehabilitate oral cancer patients for over thirty years...
April 20, 2018: British Dental Journal
https://www.readbyqxmd.com/read/29671237/acute-torrential-mitral-regurgitation-during-transcatheter-aortic-valve-replacement-a-case-report
#3
Yoshiyuki Yamashita, Hiromichi Sonoda, Tomoki Ushijima, Akira Shiose
BACKGROUND: Transcatheter aortic valve replacement (TAVR) is a minimally invasive approach to aortic valve replacement. However, critical cardiovascular collapse can occur during the procedure for various reasons. CASE PRESENTATION: A 90-year-old man with severe aortic stenosis and left circumflex artery stenosis developed acute torrential mitral regurgitation (MR) during TAVR. The valve deployment process induced left ventricular dyssynchrony due to left bundle-branch block and myocardial ischemia in the left circumflex artery region with torrential MR...
April 18, 2018: Surgical Case Reports
https://www.readbyqxmd.com/read/29670772/left-circumflex-artery-rupture-with-left-atrial-tamponade-and-functional-mitral-stenosis
#4
Weiting Huang, Khaled Mohamed Emadeldin Moheb Hammad, Victor Tar Toong Chao, Khung Keong Yeo
The growth in percutaneous transluminal devices has enabled operators to tackle more complex, native, and post-bypass surgery anatomy. However, complications such as coronary artery dissection, coronary perforation, retrograde aortic dissection, arrhythmias, and acute coronary syndrome still occur with resulting mortality rates of up to 4.2% in complex interventions. Perforation of the circumflex artery is of particular interest in view of its position and relation to the surrounding cardiac structures. This is a site of potential fluid collection, and as the left atrium is fixed to the parietal pericardium at the entry of the pulmonary veins, fluid in the oblique sinus can accumulate enough pressure to compress the left atrium and the coronary sinus...
2018: Case Reports in Cardiology
https://www.readbyqxmd.com/read/29668509/a-description-of-the-vascular-anatomy-of-the-tensor-fascia-lata-perforator-flap-using-computed-tomography-angiography
#5
Jeremy M Powers, Mariana Martinez, Shuhao Zhang, Santosh S Kale
BACKGROUND: The perforator anatomy of the tensor fascia lata (TFL) flap has been studied using cadaver dissection; however, exact descriptions of location, size, and origin of perforator vessels using preoperative imaging modalities remain limited. The aims of this study are to describe TFL perforator anatomy using high-resolution computed tomography angiography (CTA) and to correlate these findings with landmarks for the anterolateral thigh flap to facilitate flap planning. METHODS: We identified 33 patients who previously underwent bilateral lower extremity CTAs for preoperative planning of free-flap reconstruction...
April 17, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29666583/summation-and-cancellation-effects-on-qrs-and-st-segment-changes-induced-by-simultaneous-regional-myocardial-ischemia
#6
Miquel Vives-Borrás, Esther Jorge, Gerard Amorós-Figueras, Xavier Millán, Dabit Arzamendi, Juan Cinca
Simultaneous ischemia in two myocardial regions is a potentially lethal clinical condition often unrecognized whose corresponding electrocardiographic (ECG) patterns have not yet been characterized. Thus, this study aimed to determine the QRS complex and ST-segment changes induced by concurrent ischemia in different myocardial regions elicited by combined double occlusion of the three main coronary arteries. For this purpose, 12 swine were randomized to combination of 5-min single and double coronary artery occlusion: Group 1: left Circumflex (LCX) and right (RCA) coronary arteries ( n = 4); Group 2: left anterior descending artery (LAD) and LCX ( n = 4) and; Group 3: LAD and RCA ( n = 4)...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29664156/circumflex-aorta-with-double-aortic-arch-in-an-infant
#7
Ziyad M Binsalamah, Martin A Chacon-Portillo, Amy Sanyahumbi, Iki Adachi, Jeffrey S Heinle, Charles D Fraser, Carlos M Mery
Circumflex aorta and double aortic arch are two forms of rare vascular rings. We present a case of an infant who was diagnosed with circumflex aorta and double aortic arch, and describe the surgical management of this rare anomaly.
April 17, 2018: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/29659840/what-is-the-optimal-target-for-the-second-arterial-graft-in-patients-undergoing-coronary-bypass-surgery
#8
Dimos Karangelis, Amine Mazine, Apostolos Roubelakis, George Stavridis
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was whether the anterolateral or the inferior wall served as a better location for the 2nd arterial graft in a 3-system coronary artery bypass grafting procedure. In total, more than 1800 papers were found, of which 6 represented the best evidence to answer the clinical question. All papers demonstrated equivalent early postoperative mortality and morbidity. The 3 largest studies comparing bilateral internal thoracic arteries showed no difference in perioperative mortality and morbidity regardless of whether the 2nd internal thoracic artery was used to graft the left or right system...
April 5, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29657908/a-rare-case-of-coronary-artery-embolism-in-a-patient-with-d-transposition-of-the-great-arteries-with-prior-mustard-repair
#9
Prince Sethi, Udit Bhatnagar, Kelly Steffen, Edgard Bendaly, Adam Stys
The dextro-transposition of great arteries (d-TGA) is a rare, congenital, cyanotic heart disease and there is a paucity of data regarding long-term cardiovascular outcomes. We present a rare case of non-ST-elevation myocardial infarction (NSTEMI) in a patient with surgically repaired d-TGA. A 43-year-old male who had previously undergone a Mustard atrial switch palliative procedure presented with chest pain and diaphoresis and was diagnosed with NSTEMI. A coronary angiogram revealed a small, underdeveloped, left anterior descending and a large, left circumflex coronary artery with an acute embolic lesion...
February 12, 2018: Curēus
https://www.readbyqxmd.com/read/29651567/the-origin-of-the-medial-femoral-circumflex-artery-lateral-femoral-circumflex-artery-and-obturator-artery
#10
REVIEW
M Zlotorowicz, M Czubak-Wrzosek, P Wrzosek, J Czubak
INTRODUCTION: The most significant blood vessel supplying the hip joint is the medial femoral circumflex artery (MFCA). MFCA with lateral femoral circumflex artery (LFCA) are the first branches of the deep femoral artery (DFA) or they originate directly from the common femoral artery (CFA) or superficial femoral artery (SFA). PURPOSE AND METHODS: We analyzed 100 CT angiogram of the hip region [72 men, 28 women; mean age 46.4 (14-80)] to assess the frequency of each type of division of the MFCA and LFCA from either the DFA or directly from the CFA or SFA...
April 12, 2018: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/29651402/reconstruction-of-a-giant-wound-induced-by-advanced-penile-carcinoma-with-bilateral-anteromedial-thigh-flap-and-left-deep-circumflex-iliac-artery-flaps
#11
Chenyang Ji, Ruiting Li, Ganlin Zhang, Jinming Zhang, Weiqiang Liang, Yuhong Chen
A 39-year-old male patient presented with an extensive putrescent ulceration of abdominoperineal region infiltrated by advanced penile squamous cell carcinoma. To our knowledge, it is the largest defect after aggressive palliative resection of penile squamous cell carcinoma (pSCC) in the literature, which was 36×23 cm. The defect was divided into three sub-defects, and was repaired by bilateral anteromedial thigh (AMT) and left deep circumflex iliac artery (DCIA) flaps. The postoperative course was uneventful and no flap necrosis occurred...
January 2018: World Journal of Plastic Surgery
https://www.readbyqxmd.com/read/29649061/anatomical-consideration-for-the-safe-elevation-of-the-deep-circumflex-iliac-artery-in-the-flap-surgery
#12
Kang-Jae Shin, Shin-Hyo Lee, Ki-Seok Koh, Wu-Chul Song
BACKGROUND: Deep circumflex iliac artery (DCIA) osteocutaneous flap transfer was frequently applied to large defects in the maxillary and mandible regions, but the utilization rate has gradually decreased due to the complicated anatomy of the DCIA. This study investigated the comprehensive anatomy of the DCIA in relation to flap surgery with the aim of providing navigational guidelines for safe DCIA harvesting. METHODS: Sixty-two sides of the hemiabdominal wall were dissected in fixed Korean cadavers...
March 29, 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29644234/modelling-coronary-flow-after-the-norwood-operation-influence-of-a-suggested-novel-technique-for-coronary-transfer
#13
Mohammed K Al-Jughiman, Maryam A Al-Omair
Background: The dynamic behavior of the aortic sinuses has an important function in the specific characteristics of coronary blood flow. Several publications have confirmed suboptimal myocardial perfusion after the Norwood procedure. Our study was undertaken to confirm four hypotheses. First, we hypothesized that there is more resistance to coronary flow due to coronary attachments to hypoplastic aortic root and sinuses. Also, as the amalgamation of the ascending aorta with the pulmonary artery occurs above the aortic root, the coronary blood flow is not fully in antegrade pattern...
March 14, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29628407/posterior-circumflex-humeral-artery-pathology-and-digital-ischemia-in-elite-volleyball-symptoms-risk-factors-suggestions-for-clinical-management
#14
Daan van de Pol, P Paul F M Kuijer, Aart Terpstra, Marja Pannekoek-Hekman, Sena Alaeikhanehshir, Olivier Bouwmeester, R Nils Planken, Mario Maas
OBJECTIVES: To assess the association between posterior circumflex humeral artery (PCHA) pathology (PCHAP), symptoms and associated risk factors, in elite volleyball players, and to suggest profiles for clinical management and monitoring. DESIGN: Cross-sectional study. METHODS: A questionnaire assessed symptoms of digital ischemia (DI) in the dominant hand and risk factors among 278 elite indoor and beach volleyball players of whom 6.1% (17/278) was diagnosed with PCHAP using ultrasound...
March 28, 2018: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29627179/a-prostacyclin-agonist-and-an-omental-flap-increased-myocardial-blood-flow-in-a-porcine-chronic-ischemia-model
#15
Shin Yajima, Shigeru Miyagawa, Satsuki Fukushima, Yoshiki Sakai, Kayako Isohashi, Tadashi Watabe, Hayato Ikeda, Genki Horitsugi, Akima Harada, Ryoto Sakaniwa, Jun Hatazawa, Yoshiki Sawa
OBJECTIVE: We hypothesized that therapeutic efficacy may be augmented by a combination of placing a sheet immersed in ONO-1301SR, a slow-release synthetic prostacyclin agonist-inducing multiproangiogenic cytokines, over the left ventricle and a pedicled omental flap in a chronic myocardial infarct heart. METHODS: A minipig chronic myocardial infarction was generated by placing an ameroid constrictor ring around the left anterior descending artery for 4 weeks. The minipigs were then assigned into 4 groups of 6 each: sham, omental flap only, ONO-1301SR only, and ONO-1301SR combined with an omental flap (combined)...
March 11, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29618068/occipital-artery-to-posterior-cerebral-artery-bypass-using-descending-branch-of-the-lateral-circumflex-femoral-artery-graft-for-treatment-of-fusiform-unruptured-posterior-cerebral-artery-aneurysm-3-dimensional-operative-video
#16
Kristine Ravina, Ian A Buchanan, Robert C Rennert, Ben A Strickland, Joseph N Carey, Jonathan J Russin
Posterior cerebral artery (PCA) aneurysms can be technically challenging lesions due to the intricacy of perforating branches and the relationship to cranial nerves and the brainstem. Fusiform aneurysms of the perimesencephalic segment of the PCA are a rare finding which does not favor direct clip occlusion or reconstruction. In such cases, proximal parent vessel occlusion is an option for aneurysm treatment. Extracranial-intracranial (EC-IC) bypass can be used to revascularize beyond the lesion when considering proximal occlusion...
April 3, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29611602/understanding-and-modulating-the-high-energy-properties-of-noble-gas-hydrides-from-their-long-bonding-an-nbo-nrt-investigation-on-hngco-cs-osi-and-hngcn-nc-ng-he-ar-kr-xe-rn-molecules
#17
Guiqiu Zhang, Junjie Song, Lei Fu, Kongshuang Tang, Yue Su, Dezhan Chen
The noble-gas hydrides, HNgX (X is an electronegative atom or fragment), represent potential high-energy materials because their two-body decomposition process, HNgX → Ng + HX, is strongly exoergic. Our previous studies have shown that each member of the HNgX (X = halogen atom or CN/NC fragment) molecules is composed of three leading resonance structures: two ω-bonding structures (H-Ng+ :X- and H:- Ng+-X) and one long-bonding structure (H∧X). The last one paints a novel [small sigma, Greek, circumflex]-type long-bonding picture...
April 3, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29606324/comparison-of-outcomes-and-intervention-among-patients-with-non-st-segment-elevation-acute-myocardial-infarction-of-those-with-a-left-circumflex-versus-those-with-a-non-left-circumflex-related-coronary-artery-from-the-elisa-3-trial
#18
Erik A Badings, Renicus S Hermanides, Salem H K The, Jan-Henk E Dambrink, Saman Rasoul, Jan Van Wijngaarden, Esther Van 't Riet, Evelien Kolkman, Wouter S Remkes, Geert Tjeerdsma, Marloes L J Van Der Wielen, Dirk J A Lok, Harry Suryapranata, Arnoud W J Van 't Hof
Previous studies found that patients with an acute coronary syndrome (ACS) due to occlusion of the left circumflex (LC) coronary artery often present without ST-elevation, leading to a delay in diagnosis and revascularization, a larger infarct size, and a worse prognosis. In this subgroup analysis of the ELISA-3 study (early or late intervention in high-risk non-ST-segment elevation acute coronary syndromes [NSTE-ACS]) incidence, characteristics and prognosis of LC-related NSTE-ACS was investigated, and the outcome of early versus late invasive strategy was compared...
February 21, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29606297/ultra-rapid-progression-of-coronary-artery-disease-or-undiagnosed-unstable-plaque-a-brief-review-from-a-case-report
#19
REVIEW
Fernando Montenegro Sá, Catarina Ruivo, Luís Graça Santos, Alexandre Antunes, Francisco Campos Soares, José Baptista, João Morais
Coronary artery disease rarely manifests itself in the first decades of life, which explains why this population is underrepresented in clinical studies. The mechanisms and natural history of the disease seem to differ between this population and older patients. Recent studies suggest a more rapid disease progression in youth, presenting more unstable atherosclerotic plaques, although this correlation has yet to be proven. In this paper, we present the case of a 41-year-old man who presented with a non-ST elevation myocardial infarction, with percutaneous coronary intervention of the culprit lesion (70-90% lesion at bifurcation of the circumflex artery with the first marginal obtuse artery and a sub-occlusive lesion of the ramus intermedius)...
March 29, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29605952/is-the-oblique-branch-a-preferable-vascular-pedicle-for-anterolateral-thigh-free-flaps
#20
Chengliang Deng, Kaiyu Nie, Zairong Wei, Wenhu Jin, Hai Li, Shujun Li, Bihua Wu, Dali Wang
BACKGROUND:  The oblique branch of the lateral circumflex femoral artery is considered an alternative vascular pedicle of the anterolateral thigh (ALT) flap. However, the oblique branch has several advantages over the descending branch. METHODS:  A total of 61 consecutive ALT free flaps were harvested according to Yu's ABC system. Vascular pedicle dimensions and length, artery course, perforator origins, and flap harvest time with the oblique branch or the descending branch were recorded...
April 1, 2018: Journal of Reconstructive Microsurgery
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