Patricia L Valda Toro, Andrew Willmore, Nelson E Wu, Kevin L Delucchi, Alejandra Jauregui, Pratik Sinha, Kathleen D Liu, Carolyn M Hendrickson, Aartik Sarma, Lucile P A Neyton, Aleksandra Leligdowicz, Charles R Langelier, Hanjing Zhuo, Chayse Jones, Kirsten N Kangelaris, Antonio D Gomez, Michael A Matthay, Carolyn S Calfee
BACKGROUND: Rapidly improving acute respiratory distress syndrome (RIARDS) is an increasingly appreciated subgroup of ARDS in which hypoxemia improves within 24 h after initiation of mechanical ventilation. Detailed clinical and biological features of RIARDS have not been clearly defined, and it is unknown whether RIARDS is associated with the hypoinflammatory or hyperinflammatory phenotype of ARDS. The purpose of this study was to define the clinical and biological features of RIARDS and its association with inflammatory subphenotypes...
April 22, 2024: Critical Care: the Official Journal of the Critical Care Forum