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Urinary symptoms and depression

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https://www.readbyqxmd.com/read/29317663/trpv1-enhances-the-afferent-response-to-p2x-receptor-activation-in-the-mouse-urinary-bladder
#1
Luke Grundy, Donna M Daly, Christopher Chapple, David Grundy, Russ Chess-Williams
Both TRPV1 and P2X receptors present on bladder sensory nerve fibres have been implicated in mechanosensation during bladder filling. The aim of this study was to determine possible interactions between these receptors in modulating afferent nerve activity. In wildtype (TRPV1+/+) and TRPV1 knockout (TRPV1-/-) mice, bladder afferent nerve activity, intravesical pressure, and luminal ATP and acetylcholine levels were determined and also intracellular calcium responses of dissociated pelvic DRG neurones and primary mouse urothelial cells (PMUCs)...
January 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29273095/acupuncture-for-chronic-prostatitis-chronic-pelvic-pain-syndrome-study-protocol-for-a-randomized-controlled-trial
#2
Zongshi Qin, Yan Liu, Kehua Zhou, Jiani Wu, Ran Pang, Ning Li, Chang Xu, Joey S W Kwong, Zhishun Liu
BACKGROUND: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common condition affecting men of all ages. Acupuncture may be an effective treatment option for CP/CPPS, but evidence is limited. We propose to evaluate the effectiveness of acupuncture in a rigorously conducted trial. METHODS: Ten hospitals will recruit 440 participants with CP/CPPS in China from October 2017 to December 2019. Participants will be randomly allocated to acupuncture or sham acupuncture with a 1:1 ratio using computerized simple random sampling...
December 22, 2017: Trials
https://www.readbyqxmd.com/read/29230385/urinary-microbiome-and-psychological-factors-in-women-with-overactive-bladder
#3
Peng Wu, Yang Chen, Jie Zhao, Guihao Zhang, Jiawei Chen, Junpeng Wang, Huijian Zhang
Objectives: Emerging evidence indicates that alterations to the urinary microbiome are related to lower urinary tract symptoms. Overactive bladder (OAB) is a common disorder with complex etiologies and usually accompanied by psychological diseases. More information concerning the urinary microbiome and psychological factors in OAB is required. The aim of this study was to characterize the female urinary microbiome associated with OAB and investigate the relationships between urinary microbiome and psychological factors...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/29229409/postpartum-depression-screening-and-pelvic-floor-symptoms-among-women-referred-to-a-specialty-postpartum-perineal-clinic
#4
Carolyn W Swenson, Julia A DePorre, Jessica K Haefner, Mitchell B Berger, Dee E Fenner
BACKGROUND: Postpartum depression (PPD) and pelvic floor disorders are both common conditions that affect women; however, the association between the two has yet to be determined. OBJECTIVE: The aims of our study are to: 1) determine the prevalence of a positive postpartum depression screen (PPD) in a specialty postpartum perineal clinic, and 2) identify risk factors for postpartum depression in this population. STUDY DESIGN: A retrospective chart review was performed of 294 women referred to a specialty postpartum perineal clinic at the University of Michigan between March 30, 2012 and May 3, 2016...
December 8, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29175130/urinary-incontinence-is-strongly-associated-with-depression-in-middle-aged-and-older-korean-women-data-from-the-korean-longitudinal-study-of-ageing
#5
Young-Mee Lim, Sa Ra Lee, Eun Ji Choi, Kyungah Jeong, Hye Won Chung
OBJECTIVE: To investigate the relationship between urinary incontinence (UI) and depression in middle-aged and older Korean women. STUDY DESIGN: A total of 1116 participants diagnosed with UI among 7486 respondents were included in this study, using data from a well-established survey that investigated a nationally representative population: the Korean Longitudinal Study of Ageing (KLoSA). Computer-assisted personal interviewing was used to assess the status of UI and depression...
November 22, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29162085/association-of-lower-urinary-tract-symptoms-and-oab-severity-with-quality-of-life-and-mental-health-in-china-taiwan-and-south-korea-results-from-a-cross-sectional-population-based-study
#6
Kyu-Sung Lee, Tag Keun Yoo, Limin Liao, Jianye Wang, Yao-Chi Chuang, Shih-Ping Liu, Romeo Chu, Budiwan Sumarsono
BACKGROUND: Lower urinary tract symptoms (LUTS) and overactive bladder (OAB) symptoms have a substantial effect on quality of life (QoL). We report QoL and mental health results from a LUTS prevalence study in three Asian countries. METHODS: A cross-sectional, population-representative, internet-based study among individuals aged ≥40 years in China, Taiwan and South Korea. Instruments included: Overactive Bladder Symptom Score (OABSS); International Prostate Symptom Score (IPSS); other International Continence Society (ICS) symptom questions; health-related QoL 12-item short-form (HRQoL-SF12v2); Work Limitations Questionnaire (WLQ); Hospital Anxiety and Depression Scale (HADS)...
November 21, 2017: BMC Urology
https://www.readbyqxmd.com/read/29141805/treating-depression-in-multiple-sclerosis-with-antidepressants-a-brief-review-of-clinical-trials-and-exploration-of-clinical-symptoms-to-guide-treatment-decisions
#7
REVIEW
Nabeela Nathoo, Aaron Mackie
Depression is a common comorbidity in patients with multiple sclerosis (MS). Those with MS and concurrent depression have poorer quality of life and are also less likely to be compliant with disease-modifying treatment, which may ultimately affect their MS disease course. Treating depression in MS with pharmacological agents can improve not only depression, but may also impact the MS disease course. However, no guidelines exist around treating depression in MS. Few randomized-controlled trials using antidepressants in MS exist...
November 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29120894/advances-in-pharmacotherapies-for-movement-disorders-in-children-current-limitations-and-future-progress
#8
Jean-Pierre Lin
PURPOSE OF REVIEW: In childhood, movement disorders are generated by a very large number of disorders of the nervous system, and the very different developmental ages at which these occur make studies of pharmacotherapy efficacy extremely difficult. In most clinical practices, medication used in management is by trial and error, and limited by lack of efficacy and/or adverse drug reactions leading to drug intolerance. Nevertheless, symptom reduction using polypharmacy must be balanced against any accompanying comorbidities such as poor attention and concentration, constipation, ileus, urinary retention, blurred vision sedation and respiratory depression...
December 2017: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/29110958/low-level-arsenic-exposure-during-pregnancy-and-its-association-with-postpartum-depression-a-cohort-study-of-women-from-arica-chile
#9
M Valdés, A Hanchey, M P Muñoz, B Baumert, V Iglesias
BACKGROUND: While the relationship between inorganic arsenic exposure and psychological impairment has been studied previously, the association between low-level arsenic exposure during pregnancy and postpartum depression has not yet been examined. The objective is to estimate the association between low-level arsenic exposure during pregnancy and the Edinburgh score. METHODS: A sample of 223 women was collected from five public health services in Arica, Chile. Participation was voluntary and written consent was mandatory...
November 2017: Revue D'épidémiologie et de Santé Publique
https://www.readbyqxmd.com/read/29107131/the-impact-of-stress-urinary-incontinence-on-individual-components-of-quality-of-life-in-malaysian-women
#10
Renly Lim, Men Long Liong, Wing Seng Leong, Yong Khee Lau, Nurzalina Abdul Karim Khan, Kah Hay Yuen
OBJECTIVE: To assess the impact of stress urinary incontinence (SUI) on individual components of quality of life (QoL) using both condition-specific and generic questionnaires, and to compare the results of the two instruments with a control group. METHODS: Women with or without SUI aged ≥21 years old were recruited. Subjects completed the International Consultation of Incontinence-Urinary Incontinence Short Form (ICIQ-UI-SF), International Consultation of Incontinence-Lower Urinary Tract Symptoms Quality of Life (ICIQ-LUTSqol) and EQ-5D questionnaires...
October 26, 2017: Urology
https://www.readbyqxmd.com/read/29104793/increased-risk-of-erectile-dysfunction-in-men-with-multiple-sclerosis-an-italian-cross-sectional-study
#11
Raffaele Balsamo, Davide Arcaniolo, Marco Stizzo, Ester Illiano, Riccardo Autorino, Franca Natale, Elisabetta Costantini, Rocco Damiano, Marco De Sio
Introduction: Sexual dysfunctions (SDs) are common, but often underestimated symptoms in men with multiple sclerosis (MS). The most common sexual complaint in a multiple sclerosis male is erectile dysfunction (ED). The aim of this observational, cross-sectional study was to assess the prevalence of erectile dysfunction (ED) and its relationship with neurological disability, depression, urodynamic findings and lower urinary tract symptoms (LUTS) in these patients. Material and methods: From January 2014 to January 2016, there were 101 consecutive male patients with a diagnosis of Multiple Sclerosis according to the McDonald revised criteria and stable sexual relationships were included...
2017: Central European Journal of Urology
https://www.readbyqxmd.com/read/29103164/incidence-of-and-factors-associated-with-anticholinergic-drug-use-among-norwegian-women-with-urinary-incontinence
#12
Siri A Mauseth, Svetlana Skurtveit, Arnulf Langhammer, Olav Spigset
INTRODUCTION AND HYPOTHESIS: The aims of this study were to investigate patterns of prescribing anticholinergic drugs among women with urinary incontinence (UI) and to identify factors associated with prescription of these drugs. METHODS: We analysed questionnaire data on UI from 21,735 women older than 20 years who participated in a cross-sectional population-based study in Nord-Trøndelag county, Norway (the HUNT study). These data were linked at the individual level to a national prescription database, and analysed using a multivariate logistic regression model...
November 4, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/29095515/increased-odds-of-bladder-and-bowel-symptoms-in-early-parkinson-s-disease
#13
Monica C Serra, Alexus Landry, Jorge L Juncos, Alayne D Markland, Kathryn L Burgio, Patricia S Goode, Theodore M Johnson, Camille P Vaughan
AIMS: To compare the prevalence of urinary and bowel symptoms in a sample of adults with early Parkinson's disease (PD) and healthy controls (HC). METHODS: Data were obtained from the Michael J. Fox Parkinson's Progression Markers Initiative (PPMI). Prevalent bladder (urinary incontinence (UI) and nighttime voiding) and bowel (constipation and fecal incontinence (FI)) symptoms were defined as occurring at least sometimes when queried using the Scale for Outcomes in PD for Autonomic Symptoms...
November 2, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29094914/testosterone-therapy-review-of-clinical-applications
#14
REVIEW
Ryan C Petering, Nathan A Brooks
Testosterone therapy is increasingly common in the United States, and many of these prescriptions are written by primary care physicians. There is conflicting evidence on the benefit of male testosterone therapy for age-related declines in testosterone. Physicians should not measure testosterone levels unless a patient has signs and symptoms of hypogonadism, such as loss of body hair, sexual dysfunction, hot flashes, or gynecomastia. Depressed mood, fatigue, decreased strength, and a decreased sense of vitality are less specific to male hypogonadism...
October 1, 2017: American Family Physician
https://www.readbyqxmd.com/read/29056175/examining-racial-and-ethnic-differences-in-nursing-home-quality
#15
Jennifer Gaudet Hefele, Grant A Ritter, Christine E Bishop, Andrea Acevedo, Candi Ramos, Laurie A Nsiah-Jefferson, Gabrielle Katz
BACKGROUND: Identifying racial/ethnic differences in quality is central to identifying, monitoring, and reducing disparities. Although disparities across all individual nursing home residents and disparities associated with between-nursing home differences have been established, little is known about the degree to which quality of care varies by race//ethnicity within nursing homes. A study was conducted to measure within-facility differences for a range of publicly reported nursing home quality measures...
November 2017: Joint Commission Journal on Quality and Patient Safety
https://www.readbyqxmd.com/read/29045260/encopresis-plus
#16
DePorres Cormier, Marie Reilly, Amy Young, Marilyn Augustyn
Dexter is a 12-year-old boy who presents with his maternal grandmother for follow-up to primary care for secondary encopresis. Dexter presented, 18 months ago, with a 3-month history of secondary encopresis. At that time, a comprehensive assessment revealed functional constipation resulting in encopresis. Dexter's symptoms resolved with a combination of medication management and behavioral strategies; laxatives were discontinued 12 months ago.Dexter's grandmother reports that for the past 6 months, her grandson developed encopresis once again...
November 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/29040216/depressive-symptoms-screening-in-postmenopausal-women-with-symptomatic-pelvic-organ-prolapse
#17
Fangfang Ai, Mou Deng, Meng Mao, Tao Xu, Lan Zhu
OBJECTIVE: This study aimed to investigate the prevalence of depressive symptoms in postmenopausal women with symptomatic pelvic organ prolapse (POP) and to identify the factors associated with depressive symptoms in this population. METHODS: We conducted a cross-sectional study involving postmenopausal women with symptomatic POP who visited the Center of Obstetrics and Gynecology, Peking Union Medical College Hospital, Beijing, between July 2016 and March 2017...
October 16, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29017568/polychlorinated-biphenyls-and-depression-cross-sectional-and-longitudinal-investigation-of-a-dopamine-related-neurochemical-path-in-the-german-helpcb-surveillance-program
#18
Petra Maria Gaum, Monika Gube, Thomas Schettgen, Franziska Maria Putschögl, Thomas Kraus, Bruno Fimm, Jessica Lang
BACKGROUND: Exposure to polychlorinated biphenyls (PCBs) is associated with depressive symptomatology. A cause of depressive symptoms is a disturbance in the neurotransmitter system of dopamine (DA). Animal as well as human studies report that PCBs can influence the DA system. This study examined whether PCB-related depressive symptoms are affected by DA metabolites in humans with high PCB body burden. METHODS: This study is part of the German HELPcB surveillance program (Health Effects in high Level exposure to PCB) for occupationally exposed workers and their relatives...
October 10, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28988662/factors-associated-with-fatigue-in-prostate-cancer-pc-patients-undergoing-external-beam-radiation-therapy-ebrt
#19
Hann-Hsiang Chao, Abigail Doucette, David M Raizen, Neha Vapiwala
PURPOSE: Fatigue is a common adverse effect among cancer patients undergoing external beam radiation therapy (EBRT), yet the underlying disease- and treatment-related factors influencing its development are poorly understood. We hypothesized that clinical, demographic, and treatment-related factors differentially affect fatigue and aimed to better characterize variables related to fatigue development in prostate cancer (PC) patients during EBRT. METHODS AND MATERIALS: We identified a cohort of 681 patients with nonmetastatic PC undergoing a 6- to 9-week EBRT course...
September 8, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28954462/is-there-any-difference-between-depression-and-anxiety-in-overactive-bladder-according-to-sex-a-systematic-review-and-meta-analysis
#20
Iane Glauce R Melotti, Cássia Raquel Teatin Juliato, Suelene Costa de Albuquerque Coelho, Marcelo Lima, Cassio Luiz Zanettini Riccetto
PURPOSE: Overactive bladder (OAB) is characterized by urinary urgency with or without urge incontinence, accompanied by frequency and nocturia. It affects individuals of all ages and can predispose affected individuals to depression and anxiety. However, few studies have been conducted on this topic. The objective of this study was to perform a systematic review and meta-analysis assessing the symptoms of depression, anxiety, and OAB using validated instruments. METHODS: The search for articles was based on the following descriptors: overactive bladder, depression, and anxiety ("Urinary bladder, Overactive AND Depression and Anxiety") OR ("Urinary bladder, Overactive AND Depression" OR "Urinary bladder, Overactive AND Anxiety")...
September 2017: International Neurourology Journal
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