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Elderly and urinary symptoms

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https://www.readbyqxmd.com/read/29124245/thermo-expandable-prostatic-stents-for-bladder-outlet-obstruction-in-the-frail-and-elderly-population-an-underutilized-procedure
#1
Kapil Sethi, Michael Bozin, Tebogo Jabane, Richard McMullin, David Cook, Rob Forsyth, Lachlan Dodds, Lydia Johns Putra
Purpose: To report our outcomes with the use of a thermo-expandable metallic intraprostatic stent (Memokath) for patients with bladder outlet obstruction (BOO) secondary to prostatic obstruction, and to assess it is a feasible option for many frail and elderly men unsuitable for surgery. Materials and Methods: We reviewed patients who underwent insertion of a Memokath stent for BOO over 17 years (January 1999 to December 2015) at one regional center over a long follow-up period (median, 7 years)...
November 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/29113548/cognitive-functions-and-health-related-quality-of-life-in-men-with-benign-prostatic-hyperplasia-and-symptoms-of-overactive-bladder-when-treated-with-a-combination-of-tamsulosin-and-solifenacin-in-a-higher-dosage
#2
Kirill Kosilov, Irina Kuzina, Vladimir Kuznetsov, Yuliya Gainullina, Liliya Kosilova, Alexandra Prokofyeva, Sergey Loparev
AIM: To study the cognitive functions and health-related quality of life (HRQoL) in individuals taking a combination of tamsulosin and solifenacin in a higher dosage. METHODS: All patients (n = 262) were assigned to group A (N = 93, tamsulosin 0.4 mg + solifenacin 10 mg per day), group B (N = 83, tamsulosin 0.4 mg + solifenacin 20 mg), and control group C (N = 86; tamsulosin 0.4 mg + placebo). The lower urinary tract (LUT) condition was assessed on the scales International Prostate Symptom Score, Over Active Bladder Awareness Tool and uroflowmetry...
November 7, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29108511/effects-of-benign-prostate-hyperplasia-on-allografts-in-kidney-transplant
#3
Ali Murat Gokce, Mehmet Remzi Erdem, Ruhi Caglar, Cevdet Kaya, Leyla Ozel, Mesut Izzet Titiz
OBJECTIVES: Benign prostate hyperplasia is frequently diagnosed in elderly chronic renal failure patients. Although it is asymptomatic because urine flow declines in those with chronic renal failure, it may become symptomatic when urine flow increases after renal transplant. Untreated benign prostate hyperplasia may lead to several complications that adversely affect the kidney allograft. MATERIALS AND METHODS: Our retrospective study investigated data from 286 male transplant patients...
October 31, 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/29084282/qualitative-insights-into-the-experiences-of-living-with-moderate-to-severe-lower-urinary-tract-symptoms-among-community-dwelling-ageing-males
#4
Lorna Kwai Ping Suen, Hui Lin Cheng, Simon Kai Wang Yeung, Cypher Ho Au-Yeung, Jillianne Chi Yen Lee, Kathy Kit Ying Ho, Natalie Ming Yan Lau, Cristina Ka Fu Ng, Iris Wai Sze Chan
BACKGROUND: Lower urinary tract symptoms (LUTS) comprise a highly prevalent chronic condition among the aging male population. Existing literature on the experiences of men with LUTS is scarce given that only a few studies explored medical care-seeking behaviors and coping strategies. The current understanding of the experiences of elderly males with LUTS is considerably limited. Therefore, the present study aimed to identify the experiences of living with moderate-to-severe LUTS among community-dwelling Chinese ageing males and their coping strategies to facilitate the management of LUTS by healthcare providers...
2017: PloS One
https://www.readbyqxmd.com/read/29056536/predicting-risk-of-pelvic-floor-disorders-12-and-20-years-after-delivery
#5
J Eric Jelovsek, Kevin Chagin, Maria Gyhagen, Suzanne Hagen, Don Wilson, Michael W Kattan, Andrew Elders, Matthew D Barber, Björn Areskoug, Christine MacArthur, Ian Milsom
BACKGROUND: Little progress has been made in the prevention of pelvic floor disorders, despite their significant health and economic impact. The identification of women who are at risk remains a key element in targeting prevention and planning health resource allocation strategies. Although events around the time of childbirth are recognized clinically as important predictors, it is difficult to counsel women and to intervene around the time of childbirth because of an inability to convey a patient's risk accurately in the presence of multiple risk factors and the long time lapse, which is often decades, between obstetric events and the onset of pelvic floor disorders later in life...
October 19, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29042390/effect-of-point-of-care-susceptibility-testing-in-general-practice-on-appropriate-prescription-of-antibiotics-for-patients-with-uncomplicated-urinary-tract-infection-a-diagnostic-randomised-controlled-trial
#6
Anne Holm, Gloria Cordoba, Tina Møller Sørensen, Lisbeth Rem Jessen, Niels Frimodt-Møller, Volkert Siersma, Lars Bjerrum
OBJECTIVES: To investigate the effect of adding point-of-care (POC) susceptibility testing to POC culture on appropriate use of antibiotics as well as clinical and microbiological cure for patients with suspected uncomplicated urinary tract infection (UTI) in general practice. DESIGN: Open, individually randomised controlled trial. SETTING: General practice. PARTICIPANTS: Women with suspected uncomplicated UTI, including elderly patients above 65, patients with recurrent UTI and patients with diabetes...
October 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29032116/mechanisms-of-action-for-%C3%AE-1-adrenoceptor-blockers-in-storage-symptoms-with-new-insights-into-the-micturition-reflex
#7
REVIEW
Tsuyoshi Hattori, Kimio Sugaya
Elderly patients suffering from lower urinary tract symptoms with benign prostatic hyperplasia (BPH) are widely prescribed α1-adrenoceptor blockers (α1-blockers) to improve voiding and storage symptoms. The mechanism of action for improvements in voiding symptoms is well understood; tonus of the urethra and prostate are decreased and urinary flow rate is increased by α1-blockers. However, the mechanisms underlying storage symptoms have remained unclear, although detrusor hyperactivity has been identified as a significant factor...
October 11, 2017: Life Sciences
https://www.readbyqxmd.com/read/28954467/afferent-pathway-mediated-effect-of-%C3%AE-1-adrenergic-antagonist-tamsulosin-on-the-neurogenic-bladder-after-spinal-cord-injury
#8
Jin-Hee Han, Sung-Eun Kim, Il-Gyu Ko, Jayoung Kim, Khae Hawn Kim
PURPOSE: The functions of the lower urinary tract (LUT), such as voiding and storing urine, are dependent on complex central neural networks located in the brain, spinal cord, and peripheral ganglia. Thus, the functions of the LUT are susceptible to various neurologic disorders including spinal cord injury (SCI). SCI at the cervical or thoracic levels disrupts voluntary control of voiding and the normal reflex pathways coordinating bladder and sphincter functions. In this context, it is noteworthy that α1-adrenoceptor blockers have been reported to relieve voiding symptoms and storage symptoms in elderly men with benign prostatic hyperplasia (BPH)...
September 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28923679/inguinal-hernia-containing-urinary-bladder-a-case-report
#9
Milena Taskovska, Jurij Janež
INTRODUCTION: Inguinal bladder hernia is rare condition found in about 1-5% of inguinal hernias. The condition is usually diagnosed intraoperatively. Patients rarely have symptoms regarding urinary tract. The best management is surgical, open surgical technique is preferred over laparoscopic. Possible urinary tract damage during surgery should be recognized and resolved. CASE PRESENTATION: The following paper presents case of inguinal bladder hernia in 82-year old Caucasian male...
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28915942/development-of-a-validated-lc-ms-ms-method-for-the-quantification-of-19-endogenous-asthma-copd-potential-urinary-biomarkers
#10
Mona M Khamis, Darryl J Adamko, Anas El-Aneed
Obstructive airways inflammatory diseases sometimes show overlapping symptoms that hinder their early and correct diagnosis. Current clinical tests are tedious and are of inadequate specificity in special population such as the elderly and children. Therefore, we are developing tandem mass spectrometric (MS/MS) methods for targeted analysis of urine biomarkers. Recently, proton-nuclear magnetic resonance ((1)H-NMR) analysis proposed 50 urinary metabolites as potential diagnostic biomarkers among asthma and chronic obstructive pulmonary disease (COPD) patients...
October 9, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28903631/evaluation-of-overactive-bladder-and-nocturia-as-a-risk-factor-for-hip-fracture-in-climacteric-women-a-matched-pair-case-control-study
#11
Aysun Karabulut, Serap Simavlı, Ömer Demirtaş, Nusret Ök, Harun Reşit Güngör, Ali Zümrütbaş
The aim of this study was to investigate whether overactive bladder (OAB) influences hip fractures in climacteric women by comparing the frequency of OAB and nocturia symptoms in patients with hip fractures and their age-matched controls in pre-fracture period. A total of 30 climacteric patients with a history of hip fracture were compared to a control group of 51 women in terms of OAB, nocturia and nocturia-QoL. A questionnaire composed of structured questions and Turkish validated versions of the specific questionnaires for OAB, OAB-Quality of Life (OAB-q) and nocturia-QoL was directed to the two groups...
September 14, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28889761/safety-issues-associated-with-using-medication-to-treat-overactive-bladder
#12
REVIEW
George Araklitis, Linda Cardozo
The mainstay of overactive bladder treatment is the use of anticholinergic medication with its common side effects well known. This review focused on three less well-known safety issues when treating OAB. Areas covered: Patients with increased anticholinergic load are at risk of cognitive decline, dementia or even death. The elderly are particularly at risk due to polypharmacy. Botulinum toxin carries the risk of high urinary residuals, urinary tract infection and need to self catheterise. The use of vaginal oestrogens may improve OAB symptoms, but there is concern in those with a history of breast cancer...
November 2017: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/28828355/efficacy-and-safety-of-silodosin-in-the-treatment-of-lower-urinary-tract-symptoms-in-elderly-men-taking-antihypertensive-medications
#13
Woo Suk Choi, Min Chul Cho, Jeong Woo Lee, Sang Hoon Song, Jin Kyu Oh, Sang Wook Lee, Sung Yong Cho, Jae Young Park
BACKGROUND: Both hypertension and lower urinary tract symptoms (LUTS) are common conditions in the elderly population. This study investigated the efficacy and safety of silodosin in the treatment of LUTS in elderly men who were taking antihypertensive medications. METHODS: This is an observational study which collected the medical records of patients who started silodosin medication for their LUTS between April 2015 and December 2015. Inclusion criteria were age ≥ 65 years, currently taking antihypertensive medication, and International Prostate Symptom Score (IPSS) ≥ 8...
September 2017: Prostate International
https://www.readbyqxmd.com/read/28800482/targeting-phenotypic-heterogeneity-in-benign-prostatic-hyperplasia
#14
REVIEW
Douglas W Strand, Daniel N Costa, Franto Francis, William A Ricke, Claus G Roehrborn
Benign prostatic hyperplasia and associated lower urinary tract symptoms remain difficult to treat medically, resulting in hundreds of thousands of surgeries performed annually in elderly males. New therapies have not improved clinical outcomes since alpha blockers and 5 alpha reductase inhibitors were introduced in the 1990s. An underappreciated confounder to identifying novel targets is pathological heterogeneity. Individual patients display unique phenotypes, composed of distinct cell types. We have yet to develop a cellular or molecular understanding of these unique phenotypes, which has led to failure in developing targeted therapies for personalized medicine...
July 2017: Differentiation; Research in Biological Diversity
https://www.readbyqxmd.com/read/28791237/update-on-voiding-dysfunction-managed-with-suprapubic-catheterization
#15
REVIEW
Sharon F English
As the population ages the prevalence of long-term urinary catheters, especially in the elderly, is going to increase. Urinary catheters are usually placed to manage urinary retention or incontinence that cannot be managed any other way. There is significant morbidity associated with an indwelling catheter. The commonest problems are catheter blockages, infection and bladder stones. These will occur with a similar incidence with either a suprapubic or a urethral catheter. Urethral complications such as strictures, scrotal infection and erosion are less common with suprapubic catheterization (SPC)...
July 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28762621/repair-of-damaged-ligaments-with-tissue-fixation-system-minisling-is-sufficient-to-cure-major-prolapse-in-all-three-compartments-5-year-data
#16
Hiromi Inoue, Yutaka Kohata, Takanori Fukuda, Mika Monma, Yosie Uzawa, Yuina Kubo, Remi Watanabe, Takeshi Kusaka
AIM: The ageing population in Japan brings problems of pelvic organ prolapse (POP), bladder and bowel incontinence, and fragility as regards major pelvic surgery. Existing data from tissue fixation system (TFS) surgery show high cure rates for these conditions, but long-term data are lacking. We aimed to elucidate the usefulness of TFS by assessing 5-year postoperative outcomes. METHODS: A total of 68 patients, mean age 70 years, underwent total pelvic floor repair...
August 1, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28757770/recent-research-on-the-role-of-urodynamic-study-in-the-diagnosis-and-treatment-of-male-lower-urinary-tract-symptoms-and-urinary-incontinence
#17
REVIEW
Yuan-Hong Jiang, Hann-Chorng Kuo
Although evidence shows that urodynamic study may not improve outcomes, it can be used to evaluate men with lower urinary tract symptoms (LUTSs) which have not been adequately delineated and treated. In young men with LUTS not responding to treatment based on clinical examination, or elderly men with LUTS and incontinence, a complete urodynamic evaluation is mandatory to understand the pathophysiology underlying LUTS, such as bladder outlet obstruction (BOO), detrusor overactivity, and detrusor underactivity...
April 2017: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/28757756/current-consensus-and-controversy-on-the-treatment-of-male-lower-urinary-tract-symptoms-benign-prostatic-hyperplasia
#18
REVIEW
Chun-Hou Liao, Hann-Chorng Kuo
Lower urinary tract symptoms (LUTS) are highly prevalent in men and increase with age. Because LUTS are common among elderly men, they are usually considered synonymous with benign prostatic hyperplasia (BPH). Drugs should be the first-line treatment for BPH and surgical intervention should be performed only when there are complications or LUTS refractory to medical treatment. In addition to medical treatment, several minimally invasive therapies, such as thermal therapy, prostatic lift, laser evaporation, or laser enucleation techniques have been developed...
January 2017: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/28754533/benefits-and-harms-of-treatment-of-asymptomatic-bacteriuria-a-systematic-review-and-meta-analysis-by-the-european-association-of-urology-urological-infection-guidelines-panel
#19
Bela Köves, Tommaso Cai, Rajan Veeratterapillay, Robert Pickard, Thomas Seisen, Thomas B Lam, Cathy Yuhong Yuan, Franck Bruyere, Florian Wagenlehner, Riccardo Bartoletti, Suzanne E Geerlings, Adrian Pilatz, Benjamin Pradere, Fabian Hofmann, Gernot Bonkat, Björn Wullt
People with asymptomatic bacteriuria (ABU) are often unnecessarily treated with antibiotics risking adverse effects and antimicrobial resistance. We performed a systematic review to determine any benefits and harms of treating ABU in particular patient groups. Relevant databases were searched and eligible trials were assessed for risk-of-bias and Grading of Recommendations, Assessment, Development and Education quality. Where possible, a meta-analysis of extracted data was performed or a narrative synthesis of the evidence was presented...
July 25, 2017: European Urology
https://www.readbyqxmd.com/read/28753892/primary-treatment-for-prostate-cancer-in-an-elderly-man
#20
R Jeroen A van Moorselaar, Jan Hein T M van Waesberghe, André N Vis
Since the patient wanted both his lower urinary tract symptoms and his prostate cancer to be treated together, he decided to undergo robot-assisted radical prostatectomy.
July 19, 2017: European Urology Focus
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