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Elderly and urinary symptoms

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https://www.readbyqxmd.com/read/27889830/urinary-retention-in-female-oab-after-intravesical-botox-injection-who-is-really-at-risk
#1
Pawel Miotla, Rufus Cartwright, Katarzyna Skorupska, Michal Bogusiewicz, Ewa Markut-Miotla, Konrad Futyma, Tomasz Rechberger
INTRODUCTION AND HYPOTHESIS: Intravesical onabotulinumtoxinA (Botox) injections are effective for the treatment of idiopathic overactive bladder (OAB) symptoms. The aim of our study was to assess the predisposing factors for urinary retention in women with OAB after intravesical Botox injection. METHODS: All participants were women of European descent with idiopathic OAB. OnabotulinumtoxinA (100 U) was administered in 20 intra-detrusor injections. Analysis was performed based on the results of safety assessments made during follow-up (FU) visits on weeks 2, 4 and 12, in 208 women who were treated with Botox injections for refractory OAB and who completed all FU visits...
November 26, 2016: International Urogynecology Journal
https://www.readbyqxmd.com/read/27867329/caffeine-as-a-probable-factor-for-increased-risk-of-oab-development-in-elderly-people
#2
Kirill V Kosilov, Sergay A Loparev, Marina A Ivanovskaya, Liliya V Kosilova
OBJECTIVE: This study was conducted to compare overactive bladder (OAB) prevalence among people greater than 60 years of age who intake various doses of caffeine, as well as those who abstain from caffeine. PATIENTS AND METHODS: A randomized observational study was carried out in Vladivostok Gerontological Hospital. A total of 1,098 retired people greater than 60 years of age (659 women and 439 men, average age 67.1 years) took part in the study. They were admitted to the in-patient department with the purpose of annual physical examination performed in accordance with the order of the Ministry of Public Health of the Russian Federation...
October 2016: Current Urology
https://www.readbyqxmd.com/read/27845122/re-severity-of-lower-urinary-tract-symptoms-among-middle-aged-and-elderly-nigerian-men-impact-on-quality-of-life
#3
Tomas L Griebling
No abstract text is available yet for this article.
December 2016: Journal of Urology
https://www.readbyqxmd.com/read/27845121/re-the-efficacy-of-mirabegron-additional-therapy-for-lower-urinary-tract-symptoms-after-treatment-with-%C3%AE-1-adrenergic-receptor-blocker-monotherapy-prospective-analysis-of-elderly-men
#4
https://www.readbyqxmd.com/read/27824068/sulforaphane-improves-ischemia-induced-detrusor-overactivity-by-downregulating-the-enhancement-of-associated-endoplasmic-reticulum-stress-autophagy-and-apoptosis-in-rat-bladder
#5
Huai-Ching Tai, Shiu-Dong Chung, Chiang-Ting Chien, Hong-Jeng Yu
Atherosclerosis-associated pelvic ischemia has been reported to be a risk factor for bladder dysfunction and subsequent lower urinary tract symptoms (LUTS) in the elderly population. However, the molecular mechanisms of this association remain unclear. We hypothesized that stress-induced cellular responses might play a role in the pathogenesis of ischemia-induced bladder dysfunction. In the present study, the animal model of bladder ischemia was induced by bilateral partial arterial occlusion (BPAO) in rats...
November 8, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27805334/nocturia-symptom-or-a-disease
#6
REVIEW
Vyas Narayana Rao, Ganesh Gopalakrishnan, Ajit Saxena, Hemant Pathak, Divakar Dalela, Shailesh Shah, Mallikarjuna Reddy, Prasanna Kumar Mishra, Harshad Malve
Waking at night to void is known as nocturia and it is a common condition experienced by both men and women with profound impact on patient's health, quality of life, and economic condition. It is often perceived as a symptom of an organic disease, but the pathophysiology of nocturia is now well-understood, and it is considered as a disease itself. It is classified based on four different pathophysiologic mechanisms (24-hour polyuria, nocturnal polyuria, reduced bladder capacity, and sleep disorders). The association of nocturia with impaired quality of life, cardiovascular morbidity and all-cause mortality is well established...
November 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27788499/assessment-of-fosfomycin-for-complicated-or-multidrug-resistant-urinary-tract-infections-patient-characteristics-and-outcomes
#7
Stephanie E Giancola, Monica V Mahoney, Michael D Hogan, Brian R Raux, Christopher McCoy, Elizabeth B Hirsch
BACKGROUND: Bacterial resistance among uropathogens is on the rise and has led to a decreased effectiveness of oral therapies. Fosfomycin tromethamine (fosfomycin) is indicated for uncomplicated urinary tract infections (UTIs) and displays in vitro activity against multidrug-resistant (MDR) isolates; however, clinical data assessing fosfomycin for the treatment of complicated or MDR UTIs are limited. METHODS: We conducted a retrospective evaluation of patients who received ≥1 dose of fosfomycin between January 2009 and September 2015 for treatment of a UTI...
October 28, 2016: Chemotherapy
https://www.readbyqxmd.com/read/27784873/atp-release-from-bladder-urothelium-and-serosa-in-a-rat-model-of-partial-bladder-outlet-obstruction
#8
Kazuhiro Shiina, Ken-Ichiro Hayashida, Kazuo Ishikawa, Masahito Kawatani
Overactive bladder is one of the major health problem especially in elderly people. Adenosine triphosphate (ATP) is released from urinary bladder cells and acts as a smooth muscle contraction and sensory signal in micturition but little is known about the role of ATP release in the pathophysiology of overactive bladder. To assess the relationship between ATP and overactive bladder, we used a partial bladder outlet obstruction (pBOO) model in rats. The bladder caused several changes by pBOO: An increase in bladder weight, hypertrophy of sub-urothelium and sub-serosal area, and frequent non-voiding bladder contraction during urine storage...
2016: Biomedical Research
https://www.readbyqxmd.com/read/27751476/re-investigation-on-lower-urinary-tract-symptoms-luts-in%C3%A2-elderly-patients-with-prostate-cancer-pc-received-endocrine%C3%A2-therapy
#9
Tomas L Griebling
No abstract text is available yet for this article.
November 2016: Journal of Urology
https://www.readbyqxmd.com/read/27744668/the-association-between-oxidative-stress-and-depressive-symptom-scores-in-elderly-population-a-repeated-panel-study
#10
Changwoo Han, Youn-Hee Lim, Yun-Chul Hong
OBJECTIVES: Previous epidemiological studies about oxidative stress and depression are limited by hospital-based case-control design, single-time measurements of oxidative stress biomarkers, and the small number of study participants. Therefore, in this study, we analyzed the association between biomarker of oxidative stress and depressive symptom scores using repeatedly measured panel data from a community-dwelling elderly population. METHODS: From 2008 to 2010, a total of 478 elderly participants residing in Seoul, Korea, were evaluated three times...
September 2016: Journal of Preventive Medicine and Public Health, Yebang Ŭihakhoe Chi
https://www.readbyqxmd.com/read/27609058/two-parallel-pragmatic-uk-multicentre-randomised-controlled-trials-comparing-surgical-options-for-upper-compartment-vault-or-uterine-pelvic-organ-prolapse-the-vue-study-study-protocol-for-a-randomised-controlled-trial
#11
Cathryn Glazener, Lynda Constable, Christine Hemming, Suzanne Breeman, Andrew Elders, Kevin Cooper, Robert Freeman, Anthony R B Smith, Suzanne Hagen, Alison McDonald, Gladys McPherson, Isobel Montgomery, Mary Kilonzo, Dwayne Boyers, Beatriz Goulao, John Norrie
BACKGROUND: One in three women who have a prolapse operation will go on to have another operation, though not necessarily in the same compartment. Surgery can result in greater impairment of quality of life than the original prolapse itself (such as the development of new-onset urinary incontinence, or prolapse at a different site). Anterior and posterior prolapse surgery is most common (90 % of operations), but around 43 % of women also have a uterine (34 %) or vault (9 %) procedure at the same time...
September 8, 2016: Trials
https://www.readbyqxmd.com/read/27595627/-colpocleisis-guidelines-for-clinical-practice
#12
X Deffieux, T Thubert, L Donon, J-F Hermieu, L Le Normand, C Trichot
OBJECTIVE: To provide clinical practice guidelines (CPGs) based on the best evidence available (level of evidence (LE)), concerning colpocleisis as a surgical treatment of pelvic organ prolapse. METHODS: This article concern a systematically review of the literature concerning colpocleisis (obliterative surgery). RESULTS: At short term follow-up, colpocleisis is associated with an anatomical success rate of 98 % (LE3) and a subjective success rate of 93% (LE3)...
July 2016: Progrès en Urologie
https://www.readbyqxmd.com/read/27582611/review-of-current-literature-for-prostatic-artery-embolization
#13
REVIEW
Hyeon Yu, Ari J Isaacson, Charles T Burke
Prostatic artery embolization (PAE) is an emerging, novel interventional technique in the management of patients with lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH). BPH is a common clinical condition in middle-aged and elderly men resulting in LUTS, including nocturia, urinary frequency, urgency, decreased urinary flow rates, hesitancy, and incomplete bladder emptying. Traditionally, LUTSs have been managed by medical or surgical therapies. Since the initial incidental discovery that selective PAE performed for uncontrolled bleeding secondary to BPH resulted in improved LUTS, the technique has continually evolved with a growing body of evidence supporting its safety and efficacy...
September 2016: Seminars in Interventional Radiology
https://www.readbyqxmd.com/read/27582609/medical-and-surgical-treatment-modalities-for-lower-urinary-tract-symptoms-in-the-male-patient-secondary-to-benign-prostatic-hyperplasia-a-review
#14
REVIEW
Matthew Ryan Macey, Mathew C Raynor
Benign prostatic hyperplasia (BPH) with lower urinary tract symptoms (LUTS) is one of the most common ailments affecting aging men. Symptoms typically associated with BPH include weak stream, hesitancy, urgency, frequency, and nocturia. More serious complications of BPH include urinary retention, gross hematuria, bladder calculi, recurrent urinary tract infection, obstructive uropathy, and renal failure. Evaluation of BPH includes a detailed history, objective assessment of urinary symptoms with validated questionnaires, and measurement of bladder function parameters, including uroflowmetry and postvoid residual...
September 2016: Seminars in Interventional Radiology
https://www.readbyqxmd.com/read/27581314/timing-of-surgical-treatment-for-idiopathic-normal-pressure-hydrocephalus-association-between-treatment-delay-and-reduced-short-term-benefit
#15
Sharif Vakili, Dane Moran, Alice Hung, Benjamin D Elder, Lee Jeon, Hugo Fialho, Eric W Sankey, Ignacio Jusué-Torres, C Rory Goodwin, Jennifer Lu, Jamie Robison, Daniele Rigamonti
OBJECTIVE A growing body of evidence suggests that longer durations of preoperative symptoms may correlate with worse postoperative outcomes following cerebrospinal fluid (CSF) diversion for treatment of idiopathic normal pressure hydrocephalus (iNPH). The aim of this study is to determine whether the duration of preoperative symptoms alters postoperative outcomes in patients treated for iNPH. METHODS The authors conducted a retrospective review of 393 cases of iNPH involving patients treated with ventriculoperitoneal (VP) shunting...
September 2016: Neurosurgical Focus
https://www.readbyqxmd.com/read/27561366/management-of-lower-urinary-tract-symptoms-associated-with-benign-prostatic-hyperplasia-in-elderly-patients-with-a-new-diagnostic-therapeutic-and-care-pathway
#16
Antonio Carbone, Andrea Fuschi, Samer Fathi Al Rawashdah, Yazan Al Salhi, Gennaro Velotti, Andrea Ripoli, Domenico Autieri, Giovanni Palleschi, Antonio Luigi Pastore
INTRODUCTION: Benign prostatic hyperplasia (BPH) resulting in lower urinary tract symptoms (LUTS) is a widespread disease that strongly interferes with the quality of life (QoL) of elderly males. It represents a real clinical and socio-economic problem may be due to the lack of a diagnostic, therapeutic and care pathway (DTCP) tool for LUTS/BPH that considers elderly people population in its whole complexity. The aim of this study was to evaluate the clinical effectiveness of the proposed DTCP LUTS/BPH tool...
September 2016: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/27506695/linkage-of-lower-urinary-tract-symptoms-to-sleep-quality-in-elderly-men-with-nocturia-a-community-based-study-using-home-measured-electroencephalogram-data
#17
Chie Matsushita, Kazumasa Torimoto, Daisuke Goto, Yosuke Morizawa, Keisuke Kiba, Masatake Shinohara, Akihide Hirayama, Norio Kurumatani, Kiyohide Fujimoto
PURPOSE: We objectively investigated the relationship between sleep quality/efficiency and factors associated with micturition using at-home electroencephalogram assessment. MATERIALS AND METHODS: Participants were recruited from among those enrolled in the Fujiwara-kyo Study, a community based longitudinal evaluation that began in Nara Prefecture, Japan, in 2007. Included participants were men at least 65 years old who woke up in the middle of the night/early morning at least 3 times per week with the urge to void...
August 6, 2016: Journal of Urology
https://www.readbyqxmd.com/read/27473059/the-efficacy-of-mirabegron-additional-therapy-for-lower-urinary-tract-symptoms-after-treatment-with-%C3%AE-1-adrenergic-receptor-blocker-monotherapy-prospective-analysis-of-elderly-men
#18
Tomohiro Matsuo, Yasuyoshi Miyata, Katsura Kakoki, Miki Yuzuriha, Akihiro Asai, Kojiro Ohba, Hideki Sakai
BACKGROUND: Mirabegron is a β3-adrenoreceptor agonist developed for treatment of overactive bladder (OAB). α1-Adrenergic receptor blockers are effective for lower urinary tract symptoms (LUTS) in male patients. However, the efficacy of mirabegron additional treatment in elderly male patients with persistent male LUTS, especially in OAB after monotherapy with α1-adrenergic blockers, is not fully understood. METHODS: This study was conducted in male LUTS patients who were ≥ 65 years of age and had persistent OAB symptoms, regardless of whether they took an α1-adrenergic receptor blocker orally...
2016: BMC Urology
https://www.readbyqxmd.com/read/27432378/the-impact-of-central-obesity-on-storage-luts-and-urinary-incontinence-after-prostatic-surgery
#19
REVIEW
Mauro Gacci, Arcangelo Sebastianelli, Matteo Salvi, Cosimo De Nunzio, Andrea Tubaro, Stavros Gravas, Ignacio Moncada, Sergio Serni, Mario Maggi, Linda Vignozzi
In the developed and developing countries, the overall prevalence of central obesity in the elderly men is growing. In addition, the progressive aging of male population increased the possibilities of coexisting morbidities associated with obesity such as lower urinary tract symptoms (LUTS) due to benign prostatic enlargement (BPE) or to prostate cancer (PCa) needing primary treatment, including radical prostatectomy (RP), which can further adversely affect the quality of life. Simple and radical prostatectomy are the most common surgical procedures in urologic unit all over the world for BPE and PCa, respectively...
September 2016: Current Urology Reports
https://www.readbyqxmd.com/read/27418814/the-effect-of-nocturia-on-sleep-quality-and-daytime-function-in-patients-with-lower-urinary-tract-symptoms-a-cross-sectional-study
#20
I-Hung Shao, Chia-Chen Wu, Hueih-Shing Hsu, Shyh-Chyi Chang, Hsu-Hsiang Wang, Heng-Chang Chuang, Yuan-Yun Tam
BACKGROUND: Nocturia has been proven to have a negative impact on the quality of life and sleep quality in general elderly population. However, there are limited studies on the quantitative effect of nocturia on sleep quality and daytime dysfunction, specifically in patients with lower urinary tract symptoms. PATIENTS AND METHODS: During March 1, 2015 to December 31, 2015, a total of 728 patients who visited our urology department due to voiding dysfunction and experienced nocturia at least once per night were enrolled...
2016: Clinical Interventions in Aging
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