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https://www.readbyqxmd.com/read/27911100/mitochondria-and-iron-current-questions
#1
Bibbin T Paul, David H Manz, Frank M Torti, Suzy V Torti
Mitochondria are cellular organelles that perform numerous bioenergetic, biosynthetic, and regulatory functions and play a central role in iron metabolism. Extracellular iron is taken up by cells and transported to the mitochondria, where it is utilized for synthesis of cofactors essential to the function of enzymes involved in oxidation-reduction reactions, DNA synthesis and repair, and a variety of other cellular processes. Areas Covered: This article reviews the trafficking of iron to the mitochondria and normal mitochondrial iron metabolism, including heme synthesis and iron-sulfur cluster biogenesis...
December 2, 2016: Expert Review of Hematology
https://www.readbyqxmd.com/read/27911069/-urological-pathology-of-lymphatic-origin
#2
A Domènech, A Serrano, I Forner-Cordero, F Gómez, D Maldonado, C Domínguez
OBJECTIVES: Lymphatic disease is a rarely cause of some very unspecific genitourinary manifestations, assuming a diagnostic challenge in most cases. The aim of this paper is to warn about the possible etiology of these urological lymphatic presentations and discuss its management. METHODS: Retrospective review of clinical data in pediatric patients with urological pathology of lymphatic origin between 2008-2014. Three patients, two boys and a girl, were included...
January 25, 2016: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://www.readbyqxmd.com/read/27904839/noncardiac-thoracic-surgery-in-abidjan-from-1977-to-2015
#3
Yves Tanauh, Flavien Kendja, Hervé Yangni-Angate, Blaise Demine, Raphaël Ouédé, Maurice Kouacou
BACKGROUND: To report and analyze noncardiac thoracic operations performed at the Cardiology Institute of Abidjan (Institut de Cardiologie d'Abidjan) from 1977 to 2015. METHODS: This is a retrospective and descriptive study covering 39 years, from 1977 to 2015. This study period was divided into three periods of 13 years each: P1 from 1977 to 1989, P2 from 1990 to 2002 and P3 from 2003 to 2015. Medical records of 2014 operated patients were analyzed: 414 patients for P1, 464 patients for P2, 1,136 patients for P3...
October 2016: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/27869429/-topical-corticosteroids-as-a-therapeutic-alternative-in-linear-immunoglobulin-a-bullous-dermatosis-in-childhood-case-report
#4
Francisco José Gil Sáenz, Gabriel Durán Urdániz, Marta Fernández Galar, Juan Gimeno Ballester, Ana Herrero Varasa, Rosa Garcés Bordege
Linear immunoglobulin A dermatosis of childhood is a rare autoimmune disorder. Its etiology remains unknown, although it has been linked to drugs, infections, immunological diseases and lymphoproliferative processes. We report the case of a 6 year old girl who consulted for perioral bullous lesions without other symptoms. Neither treatment with mupirocin nor methylprednisolone therapy achieved remission of cutaneous lesions. Skin biopsy showed a linear immunoglobulin A dermatosis. It was not possible to start treatment with dapsone because of a partial glucose-6-phosphate dehydrogenase deficiency, so topical treatment was maintained with good evolution of lesions...
December 1, 2016: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/27866335/ophthalmic-pathology-yanoff-m-and-sassani-jw-2015-print-version-with-expert-consult-online-access-of-e-content-or-kindle-e-book-format-isbn-978-1-4557-2874-9-elsevier
#5
Zélia M Corrêa
No abstract text is available yet for this article.
December 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27865578/comparison-of-the-carlsson-dent-and-gerd-q-questionnaires-for-gastroesophageal-reflux-disease-symptom-detection-in-a-general-population
#6
R Contreras-Omaña, O Sánchez-Reyes, E Ángeles-Granados
INTRODUCTION: Gastroesophageal reflux disease (GERD) is an extremely common pathology in the general population and one of the main reasons for consultation in gastroenterology. There are different instruments for detecting its symptoms, but few studies comparing one tool with another have been conducted in Mexico. AIMS: To compare the effectiveness of the Carlsson-Dent questionnaire (CDQ) and the GERD-Q questionnaire (GQQ) in detecting GERD symptoms in a general population...
November 16, 2016: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/27863016/appropriateness-and-diagnostic-yield-of-inpatient-pediatric-echocardiograms
#7
Sean M Lang, Elijah Bolin, Joshua A Daily, Xinyu Tang, R Thomas Collins
OBJECTIVE: Multiple reports have shown echocardiograms for certain indications are neither cost-effective nor of high diagnostic yield. Given the ease with which tests can be obtained at a tertiary academic children's hospital, our aims were to: (1) determine the diagnostic yield of inpatient studies by in-hospital location; (2) evaluate inpatient echocardiograms to determine indications and level of appropriateness; and (3) evaluate the frequency of cardiology involvement prior to those echocardiograms...
November 8, 2016: Congenital Heart Disease
https://www.readbyqxmd.com/read/27862367/clinical-benefits-of-frozen-section-assessment-during-urological-surgery-does-it-contribute-to-improving-surgical-margin-status-and-patient-outcomes-as-previously-thought
#8
REVIEW
Hiroshi Miyamoto
Despite significant advances in patient selection as well as surgical technique over the past few decades, it is still not uncommon for patients with urological malignancy and positive surgical margins to be observed. Meanwhile, intraoperative pathology consultation with frozen section assessment, which generally provides useful information for the optimal procedure, has been widely utilized for the assessment of surgical margins during urological surgeries. Thus, it remains unanswered whether intraoperative frozen section assessment has an impact on final surgical margin status as well as long-term oncological outcomes...
November 8, 2016: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/27859801/a-prospective-evaluation-of-ultrasound-accuracy-in-the-prediction-of-rectosigmoid-infiltration-in-patients-with-epithelial-ovarian-cancer
#9
M Zikan, D Fischerova, I Semeradova, J Slama, P Dundr, V Weinberger, L Dusek, D Cibula
OBJECTIVES: The aim of this prospective study was to examine the accuracy of ultrasound in predicting the rectosigmoid tumor infiltration in patients with epithelial ovarian cancer. METHODS: Patients referred for suspicious pelvic mass underwent ultrasound examination within the standard protocol for the assessment of tumor infiltration. We prospectively examined 245 patients in total and included 191 patients with proven ovarian cancer who underwent primary surgery into analysis...
November 18, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27848903/-necrotising-soft-tissue-infection-of-orbital-area-and-hand-an-unusual-combination
#10
M P M Paridaans, J A Govaert, E H Scholten, D H de Lange
BACKGROUND: Necrotising soft tissue infection (NSTI) is an infection of the subcutaneous tissues and often follows a fulminant course if not recognised in time. CASE DESCRIPTION: A 78-year-old man was brought to our emergency department in septic shock. Physical examination revealed an erythematous and painful swelling of the right eyelids and to a lesser extent of the right hand. The infection progressed at both sites, and suspicion of NSTI arose. An emergency surgical debridement was performed...
2016: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/27843428/a-rare-case-of-gastric-variceal-hemorrhage-secondary-to-infiltrative-b-cell-lymphoma
#11
Adrienne Lenhart, Juan Fernandez-Castillo, Keith Mullins, Reena Salgia
Portal hypertension commonly arises in the setting of advanced liver cirrhosis and is the consequence of increased resistance within the portal vasculature. Less commonly, left-sided noncirrhotic portal hypertension can develop in a patient secondary to isolated obstruction of the splenic vein. We present a rare case of left-sided portal hypertension and isolated gastric varices in a patient with large B-cell lymphoma, who was treated with splenic artery embolization. The patient is a 73-year-old male with no previous history of liver disease, who presented with coffee ground emesis and melena...
September 2016: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/27833977/umbilical-hernia-masking-primary-umbilical-endometriosis-a-case-report
#12
Elvira Brătilă, Oana Maria Ionescu, Dumitru Cristinel Badiu, Costin Berceanu, Simona Vlădăreanu, Doina Mihaela Pop, Claudia MehedinŢu
Endometriosis is a gynecologic condition affecting mainly the pelvic organs. However, extrapelvic endometriosis has been reported in almost all parts of the body. Umbilical endometriosis, either primary or secondary, is uncommon and has a documented neoplastic risk. We present the case of a 46-year-old woman with a large umbilical hernia associating primary umbilical endometriosis discovered during surgery and confirmed later by pathological and immunohistochemical exams. The patient underwent omphalectomy and partial omentum resection, alongside with mesh abdominal wall repair...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/27833519/monocytopenia-induction-by-vinorelbine-cisplatin-and-doxorubicin-in-breast-non-small-cell-lung-and-cervix-cancer-patients
#13
Taha Nazir, Nida Taha, Azahrul Islam, Suraj Abraham, Adeel Mahmood, Mazhar Mustafa
BACKGROUND: The neoplasm is still a potential threat for breast, Non-Small Cell Lung (NSCL) and cervix cancer patients. Those gradually invade into other body organs, inducing complex pathological complications. Whereas, the anticancer drugs suppress the bone marrow, resulting serious hematological toxicities. Thus, the monocytic toxicity may the chance of infections, particularly in AID's patients. OBJECTIVE: We aimed this retrospective study to investigate the monocytopenia induced by vinorelbine following chemotherapy in cancer patients...
October 2016: International Journal of Health Sciences
https://www.readbyqxmd.com/read/27811476/factors-involved-in-vocal-fatigue-a-pilot-study
#14
Evelien D'haeseleer, Mara Behlau, Laura Bruneel, Iris Meerschman, Anke Luyten, Stien Lambrecht, Mauriceia Cassol, Paul Corthals, Maryna Kryshtopava, Floris L Wuyts, Sofie Claeys, Kristiane Van Lierde
OBJECTIVE: The purpose of this retrospective study was to determine the vocal characteristics of a treatment-seeking population with the primary complaint of vocal fatigue (VF). METHODS: Forty-three men (mean age 42 years, range 19-69) and 145 women (mean age 34 years, range 18-68) were included. None of the subjects had received voice therapy or previous laryngeal surgery. A questionnaire, laryngeal and perceptual evaluations, aerodynamic and acoustic parameters, and the Dysphonia Severity Index (DSI) were used to determine vocal characteristics...
November 4, 2016: Folia Phoniatrica et Logopaedica
https://www.readbyqxmd.com/read/27806890/the-added-value-of-pretreatment-dw-mri-in-characterization-of-salivary-glands-pathologies
#15
Peter Milad, Marwa Elbegiermy, Tamer Shokry, Heba Mahmoud, Ihab Kamal, Mohamed Shehata Taha, Nermeen Keriakos
OBJECTIVE: To evaluate the added value of diffusion weighted magnetic resonance imaging (DW-MRI) in characterization of salivary gland lesions. STUDY DESIGN: A prospective study was carried out between January 2013, and March 2015. METHODS: The study included 46 patients. The consultant radiologist, who reviewed the scans to comment on the apparent diffusion coefficient (ADC) value and ADC histogram was blind to the suspected pathology. Radiological findings were then compared to clinical and histological findings...
September 7, 2016: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/27805927/management-of-gynecomastia-in-patients-with-different-body-types-considerations-on-312-consecutive-treated-cases
#16
Alessandro Innocenti, Dario Melita, Francesco Mori, Francesco Ciancio, Marco Innocenti
BACKGROUND: Gynecomastia is a common finding in male subjects which incidence varies widely in the world population. In adolescents, it is frequently temporary but, if it becomes persistent, it generates considerable embarrassment, inducing the patients to seek surgical consultation. Even in patients with good body contour, gynecomastia creates even greater distress considering the special attention given by these subjects to their physical appearance. The authors present their experience in the treatment of gynecomastia comparing different body types of patients with the aim to investigate dissimilar expectations, needs and surgical outcomes thus optimizing the management of the pathological condition, achieving high levels of agreement and reducing unsatisfied patients arising from cosmetic surgery...
November 1, 2016: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/27801954/the-who-2016-classification-of-testicular-non-germ-cell-tumours-a-review-and-update-from-the-international-society-of-urological-pathology-testis-consultation-panel
#17
REVIEW
Muhammad T Idrees, Thomas M Ulbright, Esther Oliva, Robert H Young, Rodolfo Montironi, Lars Egevad, Daniel Berney, John R Srigley, Jonathan I Epstein, Satish K Tickoo
The World Health Organization (WHO) released a new tumour classification for the genitourinary system in early 2016 after consensus by pathologists with expertise in these organs. It utilized the framework of the 2004 classification and incorporated the most up-to-date information concerning these tumours. In testicular tumours, the majority of the changes occurred in the nomenclature and classification of the germ cell tumours; however, several modifications were also initiated for the non-germ cell tumours...
November 1, 2016: Histopathology
https://www.readbyqxmd.com/read/27800074/-neonatal-surgical-emergencies-at-the-bukavu-provincial-general-reference-hospital-in-democratic-republic-of-congo
#18
Fabrice Cikomola Gulimwentuga, Alain Namugusha Kabakuli, Aline Bedha Ndechu, Georges Kuyigwa Toha, Yvette Lufungulo Bahati, Jeff Kabinda Maotela
INTRODUCTION: This study aims to determine the prevalence of neonatal surgical emergencies and their epidemiology. METHODS: This retrospective cohort study reports 30 cases whose data were collected in the Department of Surgery at the Bukavu Provincial General Reference Hospital over a period of 3 years, from January 2010 to December 2013. RESULTS: Neonatal surgical emergencies account for 1.31% of surgical pathologies in general. The most frequent age of patients during medical consultation was less than 8 days...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27798540/physician-assistant-management-of-pediatric-patients-in-a-general-community-emergency-department-a-real-world-analysis
#19
Daniel Pavlik, Alfred Sacchetti, Amanda Seymour, Bonnie Blass
PURPOSE: Multiple studies have documented the nonclinical characteristics of physician assistant (PA) practices in the emergency department (ED). This study examines the clinical care PAs provide to younger pediatric patients in a general community ED. METHODS: The electronic medical record database of an urban community general ED was queried to identify pediatric patients aged 6 years or younger. This age group was selected because it was considered to be representative of physiologic and pathologic conditions unique to children...
October 28, 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27797247/comparison-of-effectiveness-in-differentiating-benign-from-malignant-ovarian-masses-between-iota-simple-rules-and-subjective-sonographic-assessment
#20
Theera Tongsong, Dangcheewan Tinnangwattana, Linlada Vichak-Ururote, Paponrad Tontivuthikul, Cholaros Charoenratana, Thitikarn Lerthiranwong
BACKGROUND: To compare diagnostic performance in differentiating benign from malignant ovarian masses between IOTA (the International Ovarian Tumor Analysis) simple rules and subjective sonographic assessment. MATERIALS AND METHODS: Women scheduled for elective surgery because of ovarian masses were recruited into the study and underwent ultrasound examination within 24 hours of surgery to apply the IOTA simple rules by general gynecologists and to record video clips for subjective assessment by an experienced sonographer...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
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