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Fibromyalgia vitamin d

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https://www.readbyqxmd.com/read/29123619/vitamin-d-and-fibromyalgia-a-meta-analysis
#1
REVIEW
Atekeh Hadinezhad Makrani, Mahdi Afshari, Marayam Ghajar, Zahra Forooghi, Mahmood Moosazadeh
Vitamin D is a cofactor responsible for autoimmune disorders. There is no agreement in the studies investigating the association between vitamin D and fibromyalgia. This study aims to combine the conflicting results of the primary studies which compared these patients with control groups regarding the serum concentration of vitamin D. This meta-analysis has been designed based on PRISMA guidelines. Relevant keywords were searched in PubMed, Science direct, Scopus, Cochrane, and Google scholar and primary studies were selected...
October 2017: Korean Journal of Pain
https://www.readbyqxmd.com/read/28812209/effect-of-vitamin-d-supplementation-in-chronic-widespread-pain-a-systematic-review-and-meta-analysis
#2
Wai Chung Yong, Anawin Sanguankeo, Sikarin Upala
Chronic non-specific widespread pain (CWP) including fibromyalgia (FMS) is characterized by widespread pain, reduced pain threshold, and multiple tender points on examination, causing disability and decreased quality of life. Vitamin D has been proposed as an associated factor in CWP. This meta-analysis aimed to explore the benefit of vitamin D supplementation in the management of CWP. A comprehensive search of the CENTRAL, MEDLINE, and Embase databases was performed from inception through January 2017. The inclusion criterion was the randomized clinical trials' evaluating the effects of vitamin D treatment in adult subjects with CWP or FMS...
December 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28638253/effects-of-vitamin-d-therapy-on-quality-of-life-in-patients-with-fibromyalgia
#3
Atalay Dogru, Ayse Balkarli, Veli Cobankara, Sevket Ercan Tunc, Mehmet Sahin
OBJECTIVE: The role of vitamin D in the etiopathogenesis of fibromyalgia and non-specific musculoskeletal pain is controversial. In our study, we aimed to investigate the effect of vitamin D therapy on quality of life in patients with fibromyalgia. MATERIALS AND METHODS: Seventy patients diagnosed with fibromyalgia and 65 age- and sex-matched controls were included in the study. Patients were grouped as deficient (<20 ng/mL), inadequate (20-30 ng/mL), and sufficient (>30 ng/mL) according to the levels of vitamin D...
June 2017: Eurasian Journal of Medicine
https://www.readbyqxmd.com/read/28627205/a-low-fermentable-oligo-di-mono-saccharides-and-polyols-fodmap-diet-is-a-balanced-therapy-for-fibromyalgia-with-nutritional-and-symptomatic-benefits
#4
Ana Paula Marum, Cátia Moreira, Pablo Tomas-Carus, Fernando Saraiva, Catarina Sousa Guerreiro
INTRODUCTION: Fibromyalgia is a chronic rheumatic disease producing widespread pain, associated to a major comorbidity -irritable bowel syndrome. Low FODMAPS diet (low fermentable oligo-di-mono-saccharides and polyols diet) has been effective in controlling irritable bowel syndrome symptoms. Overweight is an aggravating factor for fibromyalgia. We studied effects of low fermentable oligo-di-mono-saccharides and polyols diets on fibromyalgia symptoms and weight status. METHODS: A longitudinal study was performed on 38 fibromyalgia patients using a four-week, repeated assessment as follow: M1 = first assessments/presentation of individual low fermentable oligo-di-mono-saccharides and polyols diet; M2 = second assessments/reintroduction of FODMAPs; M3 = final assessments/nutritional counselling...
June 5, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28536294/the-interfaces-between-vitamin-d-sleep-and-pain
#5
REVIEW
Daniela Leite de Oliveira, Camila Hirotsu, Sergio Tufik, Monica Levy Andersen
The role of vitamin D in osteomineral metabolism is well known. Several studies have suggested its action on different biological mechanisms, such as nociceptive sensitivity and sleep-wake cycle modulation. Sleep is an important biological process regulated by different regions of the central nervous system, mainly the hypothalamus, in combination with several neurotransmitters. Pain, which can be classified as nociceptive, neuropathic and psychological, is regulated by both the central and peripheral nervous systems...
July 2017: Journal of Endocrinology
https://www.readbyqxmd.com/read/28478843/respiratory-alkalosis-may-impair-the-production-of-vitamin-d-and-lead-to-significant-morbidity-including-the-fibromyalgia-syndrome
#6
John M Lewis, Toinette H Fontrier, J Lynn Coley
Hyperventilation caused by physical and/or psychological stress may lead to significant respiratory alkalosis and an elevated systemic pH. The alkalotic pH may in turn suppress the normal renal release of phosphate into the urine, thereby interrupting the endogenous production of 1,25-dihydroxyvitamin D (calcitriol). This could cause a shortfall in its normal production, leading to a variety of adverse consequences. It might partially explain the pathogenesis of acute mountain sickness, a treatable disease characterized by severe hyperventilation secondary to the hypoxia of high altitude exposure...
May 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28075425/management-of-fibromyalgia-practical-guides-from-recent-evidence-based-guidelines
#7
REVIEW
Winfried Häuser, Jacob Ablin, Serge Perrot, Mary-Ann Fitzcharles
Fibromyalgia (FM) is a prevalent and costly condition worldwide, affecting approximately 2% of the general population. Recent evidence- and consensus‑based guidelines from Canada, Germany, Israel, and the European League Against Rheumatism aim to support physicians in achieving a comprehensive diagnostic workup of patients with chronic widespread (generalized) pain (CWP) and to assist patients and physicians in shared decision making on treatment options. Every patient with CWP requires, at the first medical evaluation, a complete history, medical examination, and some laboratory tests (complete blood count, measurement of C‑reactive protein, serum calcium, creatine phosphokinase, thyroid‑stimulating hormone, and 25‑hydroxyvitamin D levels) to screen for metabolic or inflammatory causes of CWP...
January 4, 2017: Polish Archives of Internal Medicine
https://www.readbyqxmd.com/read/27860257/efficacy-of-vitamin-d-replacement-therapy-on-patients-with-chronic-nonspecific-widespread-musculoskeletal-pain-with-vitamin-d-deficiency
#8
Ramazan Yilmaz, Ali Salli, Havva Turac Cingoz, Sami Kucuksen, Hatice Ugurlu
AIM: The objective of this study is the evaluation of the effect of vitamin D replacement treatment on musculoskeletal symptoms and quality of life in patients with chronic widespread musculoskeletal pain (CWP) including fibromyalgia (FM) and vitamin D deficiency. METHOD: Patients with nonspecific CWP and vitamin D deficiency (25-OH D3 < 25 ng/mL) were included into the study. Replacement treatments of 50 000 IU/week oral vitamin D3 for 3 months were given to the patients...
December 2016: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/27846770/the-relationship-between-balance-and-vitamin-25-oh-d-in-fibromyalgia-patients
#9
Meliha Kasapoğlu Aksoy, Lale Altan, Burcu Ökmen Metin
INTRODUCTION: Fibromyalgia syndrome (FMS) is a chronic disease characterized by diffuse pain of unknown cause, fatigue, sleep disorders, cognitive dysfunction, and sensitivity. Fibromyalgia was shown to be associated with balance problems and increased incidence of falls. There are many theoretical mechanisms related to the impact of vitamin D on postural control. The aim of the current study was to investigate the relationship between vitamin 25(OH)D levels and pain, balance and daily activities in patients with FMS...
December 9, 2016: Modern Rheumatology
https://www.readbyqxmd.com/read/27413482/serum-vitamin-d-status-in-iranian-fibromyalgia-patients-according-to-the-symptom-severity-and-illness-invalidation
#10
Alireza Amir Maafi, Banafsheh Ghavidel-Parsa, Afrooz Haghdoost, Yasaman Aarabi, Asghar Hajiabbasi, Irandokht Shenavar Masooleh, Habib Zayeni, Babak Ghalebaghi, Amir Hassankhani, Ali Bidari
BACKGROUND: This study was designed to assess serum vitamin D status (25-OHD) in the fibromyalgia (FM) patients and to compare it with a healthy control group. It also aimed to investigate the correlation of serum vitamin D level with FM symptom severity and invalidation experiences. METHODS: A total of 74 consecutive patients with FM and 68 healthy control participants were enrolled. The eligible FM patients completed the Illness Invalidation Inventory (3(*)I), the Revised Fibromyalgia Impact Questionnaire (FIQR) and a short-form health survey (SF-12)...
July 2016: Korean Journal of Pain
https://www.readbyqxmd.com/read/27271665/vitamin-d-in-fibromyalgia-a-causative-or-confounding-biological-interplay
#11
REVIEW
Spyridon Karras, Eleni Rapti, Stauros Matsoukas, Kalliopi Kotsa
Fibromyalgia (FM) is a chronic syndrome with an increasing prevalence, characterized by widespread musculoskeletal pain in combination with a variety of cognitive symptoms and fatigue. A plethora of scientific evidence that has accumulated during the last decades, resulted in a significant improvement of the understanding of the pathophysiology of the disease. However, current therapeutic approaches in patients with FM remains a multidimensional approach including patient education, behavioral therapy, exercise, pain management, and relief of chronic symptoms, rather than the use drug therapies, based on the mechanisms of disease development...
June 4, 2016: Nutrients
https://www.readbyqxmd.com/read/27267522/food-intake-assessment-and-quality-of-life-in-women-with-fibromyalgia
#12
Emmanuelle Dias Batista, Aline Andretta, Renata Costa de Miranda, Jéssica Nehring, Eduardo Dos Santos Paiva, Maria Eliana Madalozzo Schieferdecker
OBJECTIVE: To compare the food intake of women with and without fibromyalgia and verify if the food intake of patients with fibromyalgia interferes with the pain and quality of life. METHODS: Study participants were women with fibromyalgia (FM) seen in Fibromyalgia Outpatient Clinic, Hospital das Clínicas/UFPR and a control group (CT) with healthy women. Data collection was conducted from March to October 2012. For the assessment of food intake we used the Food Registration and the analyzed items were total calories, carbohydrates, proteins, lipids, vitamins (A, C, B12, D and E) and minerals (folate, selenium, zinc, iron, calcium and magnesium)...
March 2016: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/27135653/relationship-between-foki-polymorphism-in-the-vitamin-d-receptor-gene-and-fibromyalgia-syndrome
#13
Erdem Maraslı, Senay Ozdolap, Selda Sarıkaya
AIM: The aim of this study was to evaluate the vitamin D receptor (VDR) gene FokI polymorphism frequencies distribution in subjects with fibromyalgia syndrome (FMS) compared to healthy controls. METHOD: Using a case-control design, 100 female patients, who were diagnosed with FMS according to the American College of Rheumatology criteria and 100 healthy female subjects were enrolled in this study. FokI polymorphisms of the VDR gene were analyzed by restriction fragment length polymorphisms (RFLP) in both groups...
November 2016: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/26774507/low-vitamin-d-and-the-risk-of-developing-chronic-widespread-pain-results-from-the-european-male-ageing-study
#14
MULTICENTER STUDY
Paul S McCabe, Stephen R Pye, John Mc Beth, David M Lee, Abdelouahid Tajar, Gyorgy Bartfai, Steven Boonen, Roger Bouillon, Felipe Casanueva, Joseph D Finn, Gianni Forti, Aleksander Giwercman, Ilpo T Huhtaniemi, Krzysztof Kula, Neil Pendleton, Margus Punab, Dirk Vanderschueren, Frederick C Wu, Terence W O'Neill
BACKGROUND: The association between low levels of vitamin D and the occurrence of chronic widespread pain (CWP) remains unclear. The aim of our analysis was to determine the relationship between low vitamin D levels and the risk of developing CWP in a population sample of middle age and elderly men. METHODS: Three thousand three hundred sixty nine men aged 40-79 were recruited from 8 European centres for a longitudinal study of male ageing, the European Male Ageing Study...
January 16, 2016: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/26315451/prevalence-and-clinical-impact-of-fibromyalgia-in-patients-with-primary-sj%C3%A3-gren-s-syndrome
#15
Byoong Yong Choi, Hye Jin Oh, Yun Jong Lee, Yeong Wook Song
OBJECTIVES: Clinical features of primary Sjögren's syndrome (pSS) overlap with those of fibromyalgia (FM). This cross-sectional study was conducted to investigate the prevalence of FM in pSS patients and to compare the clinical features of pSS patients with FM to those without FM. METHODS: One hundred pSS patients were consecutively assessed to identify the presence of FM according to the American College of Rheumatology (ACR) 2010 criteria. Clinical and laboratory data were collected from all patients...
March 2016: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/26307663/-food-intake-assessment-and-quality-of-life-inwomen-with-fibromyalgia
#16
Emmanuelle Dias Batista, Aline Andretta, Renata Costa de Miranda, Jéssica Nehring, Eduardo Dos Santos Paiva, Maria Eliana Madalozzo Schieferdecker
OBJECTIVE: To compare the food intake of women with and without fibromyalgia and verify if the food intake of patients with fibromyalgia interferes with the pain and quality of life. METHODS: Study participants were women with fibromyalgia (FM) seen in Fibromyalgia Outpatient Clinic, Hospital das Clínicas/UFPR and a control group (CT) with healthy women. Data collection was conducted from March to October 2012. For the assessment of food intake we used the Food Registration and analyzed items were: total calories, carbohydrates, proteins, lipids, vitamins (A, C, B12, D and E) and minerals (folate, selenium, zinc, iron, calcium and magnesium)...
August 12, 2015: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/25291242/vitamin-d-status-in-rheumatoid-arthritis-patients-relation-to-clinical-manifestations-disease-activity-quality-of-life-and-fibromyalgia-syndrome
#17
Tamer A Gheita, Safaa Sayed, Heba A Gheita, Sanaa A Kenawy
AIM: To assess vitamin D levels in rheumatoid arthritis (RA) patients and to find their relation to clinical parameters, fibromyalgia syndrome (FMS), quality of life (QoL) and disease activity. METHODS: The study included 63 RA patients and 62 controls. Clinical examination and laboratory investigations were performed. For patients, the Disease Activity Score (DAS-28), QoL index, Health Assessment Questionnaire II (HAQ II) and Modified Larsen score were calculated...
March 2016: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/24985043/prevalence-of-primary-hyperparathyroidism-in-a-referred-sample-of-fibromyalgia-patients
#18
MULTICENTER STUDY
Robert Ferrari, Anthony Science Russell
The objective of this study is to determine the prevalence of primary hyperparathyroidism in a referred sample of fibromyalgia patients. Consecutively, referred patients with confirmed fibromyalgia (FM group) had measurements of serum levels of vitamin D, alkaline phosphatase, total calcium, magnesium, phosphate, creatinine, total protein, albumin, and parathyroid hormone. The same measurements were also conducted in a group of patients with widespread pain (WP group) who did not meet the 2010 Modified ACR criteria for fibromyalgia and a group with localized musculoskeletal pain (MSK group)...
July 2015: Clinical Rheumatology
https://www.readbyqxmd.com/read/24811356/-metabolic-bone-disease-osteomalacia
#19
REVIEW
M A Reuss-Borst
Osteomalacia is a rare disorder of bone metabolism leading to reduced bone mineralization. Underlying vitamin D deficiency and a disturbed phosphate metabolism (so-called hypophosphatemic osteomalacia) can cause the disease. Leading symptoms are dull localized or generalized bone pain, muscle weakness and cramps as well as increased incidence of falls. Rheumatic diseases, such as polymyalgia rheumatica, rheumatoid arthritis, myositis and fibromyalgia must be considered in the differential diagnosis. Alkaline phosphatase (AP) is typically elevated in osteomalacia while serum phosphate and/or 25-OH vitamin D3 levels are reduced...
May 2014: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/24760247/osteomalacia-mimicking-spondyloarthropathy-a-case-report
#20
Y Garip, M Dedeoglu, H Bodur
Osteomalacia is a metabolic bone disorder characterized by impaired mineralization of bone matrix. Symptoms of osteomalacia can be confused with other conditions such as spondyloarthropathy, polymyalgia rheumatica, polymyositis, and fibromyalgia. In this case, we report a patient with axial osteomalacia who developed low back pain, morning stiffness, and "grade 3 sacroiliitis" in pelvis X-ray, leading to the misdiagnosis as seronegative spondyloarthropathy. Serum biochemical studies revealed low serum phosphorus, low 25-hydroxy vitamin D3, normal calcium, elevated parathyroid hormone, and alkaline phosphatase levels...
July 2014: Osteoporosis International
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