keyword
https://read.qxmd.com/read/38642261/basal-insulinotherapy-in-patients-living-with-diabetes-in-france-the-ef-bi-study
#21
JOURNAL ARTICLE
Pierre Gourdy, Patrice Darmon, Isabelle Borget, Corinne Emery, Isabelle Bureau, Bruno Detournay, Amar Bahloul, Noemie Allali, Aymeric Mahieu, Alfred Penfornis
INTRODUCTION: Second-generation basal insulins like glargine 300 U/mL (Gla-300) have a longer duration of action and less daily fluctuation and interday variability than first-generation ones, such as glargine 100 U/mL (Gla-100). The EF-BI study, a nationwide observational, retrospective study, was designed to compare persistence, acute care complications, and healthcare costs associated with the initiation of such basal insulins (BI) in a real-life setting in France. METHODS: This study was conducted using the French healthcare claims database (SNDS)...
April 20, 2024: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://read.qxmd.com/read/38642248/clinical-impact-of-an-individualised-clinical-pharmacy-programme-into-the-memory-care-pathway-of-older-people-an-observational-study
#22
JOURNAL ARTICLE
Teddy Novais, Elsa Reallon, Julie Martin, Marine Barral, Pierre Krolak-Salmon, Marie-Hélène Coste, Hanane Zenagui, Antoine Garnier-Crussard, Delphine Hoegy, Christelle Mouchoux
BACKGROUND: In older patients, medication exposure [i.e. polypharmacy, potentially inappropriate medications (PIMs), medications with anticholinergic and/or sedative properties] is a modifiable risk factor associated with cognitive iatrogenic risk and dementia. AIM: To assess the potential clinical impact of the implementation of an individualised clinical pharmacy programme at the initiation of the Memory care pathway in older patients with a cognitive complaint...
April 20, 2024: International Journal of Clinical Pharmacy
https://read.qxmd.com/read/38641650/microbiological-features-of-drowning-associated-pneumonia-a-systematic-review-and-meta-analysis
#23
REVIEW
Vladimir L Cousin, Laure F Pittet
BACKGROUND: Drowning-associated pneumonia (DAP) is frequent in drowned patients, and possibly increases mortality. A better understanding of the microorganisms causing DAP could improve the adequacy of empirical antimicrobial therapy. We aimed to describe the pooled prevalence of DAP, the microorganisms involved, and the impact of DAP on drowned patients. METHODS: Systematic review and meta-analysis of studies published between 01/2000 and 07/2023 reporting on DAP occurrence and microorganisms involved...
April 20, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38641571/a-methodology-for-estimating-sars-cov-2-importation-risk-by-air-travel-into-canada-between-july-and-november-2021
#24
JOURNAL ARTICLE
Rachael M Milwid, Vanessa Gabriele-Rivet, Nicholas H Ogden, Patricia Turgeon, Aamir Fazil, David London, Simon de Montigny, Erin E Rees
BACKGROUND: Estimating rates of disease importation by travellers is a key activity to assess both the risk to a country from an infectious disease emerging elsewhere in the world and the effectiveness of border measures. We describe a model used to estimate the number of travellers infected with SARS-CoV-2 into Canadian airports in 2021, and assess the impact of pre-departure testing requirements on importation risk. METHODS: A mathematical model estimated the number of essential and non-essential air travellers infected with SARS-CoV-2, with the latter requiring a negative pre-departure test result...
April 19, 2024: BMC Public Health
https://read.qxmd.com/read/38640962/association-between-visual-acuity-and-prospective-fall-risk-in-generally-healthy-and-active-older-adults-the-3-year-do-health-study
#25
JOURNAL ARTICLE
Maud Wieczorek, Marlis Isler, Klara Landau, Matthias D Becker, Bess Dawson-Hughes, Reto W Kressig, Bruno Vellas, Endel John Orav, René Rizzoli, John A Kanis, Gabriele Armbrecht, José António P Da Silva, Andreas Egli, Gregor Freystätter, Heike A Bischoff-Ferrari
OBJECTIVE: Although aging has a strong impact on visual acuity (VA) and falls, their interaction is understudied in generally healthy older adults. This study aimed to examine if and to what extent baseline VA is associated with an increased risk of all and injurious falls over 3 years in generally healthy community-dwelling older adults. DESIGN: Observational analysis of DO-HEALTH, a double-blind, randomized controlled trial. SETTING AND PARTICIPANTS: Multicenter trial with 7 European centers: Zurich, Basel, Geneva (Switzerland), Berlin (Germany), Innsbruck (Austria), Toulouse (France), and Coimbra (Portugal), including 2157 community-dwelling adults aged 70 years and older without any major health events in the 5 years prior to enrollment, sufficient mobility, and good cognitive status...
April 16, 2024: Journal of the American Medical Directors Association
https://read.qxmd.com/read/38640772/atrial-fibrillation-and-preexisting-cognitive-impairment-in-ischemic-stroke-patients-dijon-stroke-registry
#26
JOURNAL ARTICLE
Thibaut Pommier, Gauthier Duloquin, Valentin Pinguet, Pierre-Olivier Comby, Charles Guenancia, Yannick Béjot
BACKGROUND: Atrial Fibrillation (AF) is a common cause of ischemic stroke (IS), and is associated with cognitive impairment in the general population. We aimed to compare the prevalence of preexisting cognitive impairment between IS patients with and without AF, and to assess whether prior brain damage could contribute to the observed differences. METHODS: Patients with acute IS were prospectively identified from the population-based Dijon Stroke Registry, France...
April 15, 2024: Archives of Gerontology and Geriatrics
https://read.qxmd.com/read/38640228/-the-review-of-the-monograph-ambroise-par%C3%A3-the-first-surgeon-of-the-kingdom-by-e-e-berger
#27
JOURNAL ARTICLE
P E Ratmanov
The review considers the approach placing famous French surgeon A. Paré into more general European context of European Renaissance of XVI century and into local context of intellectual life of Paris of this period. The refutation of widespread in history of medicine opinion about strict separation of university medicine from artisan surgery in Medieval Europe is discussed.
March 2024: Problemy Sot︠s︡ialʹnoĭ Gigieny, Zdravookhranenii︠a︡ i Istorii Medit︠s︡iny
https://read.qxmd.com/read/38640090/relying-on-the-french-territorial-offer-of-thermal-spa-therapies-to-build-a-care-pathway-for-long-covid-19-patients
#28
JOURNAL ARTICLE
Milhan Chaze, Laurent Mériade, Corinne Rochette, Mélina Bailly, Rea Bingula, Christelle Blavignac, Martine Duclos, Bertrand Evrard, Anne Cécile Fournier, Lena Pelissier, David Thivel
BACKGROUND: Work on long COVID-19 has mainly focused on clinical care in hospitals. Thermal spa therapies represent a therapeutic offer outside of health care institutions that are nationally or even internationally attractive. Unlike local care (hospital care, general medicine, para-medical care), their integration in the care pathways of long COVID-19 patients seems little studied. The aim of this article is to determine what place french thermal spa therapies can take in the care pathway of long COVID-19 patients...
2024: PloS One
https://read.qxmd.com/read/38639533/the-global-impact-of-sars-cov-2-variant-ba-2-86-a-comprehensive-analysis-with-the-latest-developments-and-transmission-trends-an-epidemiological-study
#29
JOURNAL ARTICLE
S A Meo, A S Meo, D M Halepoto
OBJECTIVE: The variant BA.2.86 of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing concern globally. The virus contains a large number of mutations, and transmission trends are rapidly changing globally. This study investigates the global epidemiological and transmission trends of SARS-CoV-2 new variant BA.2.86 in various continents and countries. MATERIALS AND METHODS: The data were recorded using key terms, including SARS-CoV-2, Omicron, BA...
April 2024: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/38639017/a-roadmap-for-therapeutic-discovery-in-pulmonary-hypertension-associated-with-left-heart-failure-a-scientific-statement-of-the-heart-failure-association-hfa-of-the-esc-and-the-esc-working-group-on-pulmonary-circulation-right-ventricular-function
#30
JOURNAL ARTICLE
Pietro Ameri, Valentina Mercurio, Piero Pollesello, Markus S Anker, Johannes Backs, Antoni Bayes-Genis, Barry A Borlaug, Daniel Burkhoff, Sergio Caravita, Stephen Y Chan, Frances de Man, George Giannakoulas, Aránzazu González, Marco Guazzi, Paul M Hassoun, Anna R Hemnes, Cristoph Maack, Brendan Madden, Vojtech Melenovsky, Oliver J Müller, Zoltan Papp, Soni Savai Pullamsetti, Peter P Rainer, Margaret M Redfield, Stuart Rich, Gabriele G Schiattarella, Hall Skaara, Kostantinos Stellos, Ryan J Tedford, Thomas Thum, Jean Luc Vachiery, Peter van der Meer, Sophie Van Linthout, Piotr Pruszczyk, Petar Seferovic, Andrew J S Coats, Marco Metra, Giuseppe Rosano, Stephan Rosenkranz, Carlo Gabriele Tocchetti
Pulmonary hypertension (PH) associated with left heart failure (LHF) (PH-LHF) is one of the most common causes of PH. It directly contributes to symptoms and reduced functional capacity and negatively affects right heart function, ultimately leading to a poor prognosis. There are no specific treatments for PH-LHF, despite the high number of drugs tested so far. This scientific document addresses the main knowledge gaps in PH-LHF with emphasis on pathophysiology and clinical trials. Key identified issues include better understanding of the role of pulmonary venous versus arteriolar remodelling, multidimensional phenotyping to recognize patient subgroups positioned to respond to different therapies, and conduct of rigorous pre-clinical studies combining small and large animal models...
April 19, 2024: European Journal of Heart Failure
https://read.qxmd.com/read/38638947/reinforcement-during-the-covid-19-pandemic-perception-of-nursing-students-and-impact-on-intention-to-drop-out-of-nursing-education
#31
JOURNAL ARTICLE
Maxime Thorigny, Pascal Didelot, Leïla Bouazzi, Bach-Nga Pham, Coralie Barbe
BACKGROUND: Although the COVID-19 pandemic's impact on students has already been studied, its impact on nursing students' perception of their training and their conception of their future profession is unknown. AIMS: To describe nursing students' perception of their involvement in reinforcement during the COVID-19 pandemic and the impact of working as reinforcement staff during the COVID-19 pandemic on nursing students. DESIGN: Cross-sectional, comparative case/non-case study...
April 30, 2024: Heliyon
https://read.qxmd.com/read/38638716/to-evaluate-different-endodontic-instrumentation-systems-regarding-post-operative-pain-after-endodontic-therapy-a-clinical-study
#32
JOURNAL ARTICLE
Bharath Gowda Govindiah Chandra Mohan, Disha Shivakumar, Sravana Laxmi Penumaka, Shaik Althaf, Garima Garg, Savadamoorthi Kamatchi Subramani
BACKGROUND: Despite substantial breakthroughs in instrumentation systems and pharmaceutical interventions, pain following endodontic therapy remains a serious concern. The effect of the type of endodontic instrumentation system in post-operative pain after endodontic therapy has been a matter of debate. AIM: To evaluate different endodontic instrumentation systems, namely Reciproc (GmbH, Munich), OneShape® (MicroMega, France), Protaper Gold (Dentsply Sirona, USA), and Hyflex® EDM (Coltène/Whaledent Inc...
March 2024: Curēus
https://read.qxmd.com/read/38638309/technical-success-procedural-safety-and-efficacy-of-the-silk-vista-baby-in-the-treatment-of-cerebral-aneurysms-over-a-mid-to-long-term-follow-up
#33
JOURNAL ARTICLE
Claudio Rodríguez-Fernández, Pedro Ruiz-Garcia, Maria Jesús Garcia-Sanchez, Martiel Manrique-Zegarra, Carlos Toledano-Illán, Jorge Escartin, Miguel Angel Vences, Luis Angel Rubio, Alex Luttich, José Manuel Pumar
BACKGROUND: Long-term follow-up of cerebral aneurysms treated with the Silk Vista Baby (SVB) flow diverter is lacking. This study aimed to assess the technical success, procedural safety, and efficacy of the SVB (Balt, Montmorency, France) for the treatment of intracranial aneurysms in small cerebral vessels over a mid-to long-term follow-up. METHODS: We retrospectively analyzed a prospectively maintained database of patients treated with the SVB between September 2018 and June 2021...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38638272/adieu-bias-debiasing-intuitions-among-french-speakers
#34
JOURNAL ARTICLE
Nina Franiatte, Esther Boissin, Alexandra Delmas, Wim De Neys
Recent debiasing studies have shown that a short, plain-English explanation of the correct solution strategy can improve reasoning performance. However, these studies have predominantly focused on English-speaking populations, who were tested with problem contents designed for an English-speaking test environment. Here we explore whether the key findings of previous debiasing studies can be extended to native French speakers living in continental Europe (France). We ran a training session with a battery of three reasoning tasks (i...
2024: Psychologica Belgica
https://read.qxmd.com/read/38638018/-motivational-factors-for-early-option-choice-by-laboratory-medicine-residents-in-france
#35
JOURNAL ARTICLE
Enagnon Kazali Alidjinou, Quentin Pomorski, Maxence Bauvais, Annabelle Dupont, Frédéric Grenouillet, Myriam Labalette, Boualem Sendid, Thierry Brousseau, Didier Hober, Olivier Nicolas
In France, both students from medicine and pharmacy background can have access to the residency in laboratory medicine (LM). The current curriculum of LM residency includes an early choice of option after the first two years of residency, which subsequently guides the rest of the training. This study aimed to analyze these choice and motivational factors, since its implementation in 2017. A national survey was conducted among LM residents and former residents who underwent the early option choice process. A questionnaire was developed and sent to residents via Google Forms...
April 19, 2024: Annales de Biologie Clinique
https://read.qxmd.com/read/38638016/-newborn-screening-in-france-news-and-perspectives
#36
JOURNAL ARTICLE
Emeline Gernez, Estelle Roland, Claire-Marie Dhaenens, Gilles Renom, Karine Mention
Newborn screening is a major public health concern. In France, it was established in 1972 with systematic screening for phenylketonuria. Subsequently, other screenings, including congenital hypothyroidism, congenital adrenal hyperplasia, cystic fibrosis, and sickle cell disease, were added. The introduction of tandem mass spectrometry in screening laboratories in 2020 enabled the inclusion of eight additional inherited metabolic diseases: aminoacidopathies (tyrosinemia type I, maple syrup urine disease, and homocystinuria), organic acidurias (isovaleric and glutaric type I acidurias), and disorders of fatty acid metabolism (MCADD, long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHADD), and primary carnitine deficiency)...
April 19, 2024: Annales de Biologie Clinique
https://read.qxmd.com/read/38637798/integrating-training-in-evidence-based-medicine-and-shared-decision-making-a-qualitative-study-of-junior-doctors-and-consultants
#37
JOURNAL ARTICLE
Mary Simons, Georgia Fisher, Samantha Spanos, Yvonne Zurynski, Andrew Davidson, Marcus Stoodley, Frances Rapport, Louise A Ellis
BACKGROUND: In the past, evidence-based medicine (EBM) and shared decision-making (SDM) have been taught separately in health sciences and medical education. However, recognition is increasing of the importance of EBM training that includes SDM, whereby practitioners incorporate all steps of EBM, including person-centered decision-making using SDM. However, there are few empirical investigations into the benefits of training that integrates EBM and SDM (EBM-SDM) for junior doctors, and their influencing factors...
April 18, 2024: BMC Medical Education
https://read.qxmd.com/read/38637119/magnitude-and-determinants-of-excess-total-age-specific-and-sex-specific-all-cause-mortality-in-24-countries-worldwide-during-2020-and-2021-results-on-the-impact-of-the-covid-19-pandemic-from-the-c-mor-project
#38
JOURNAL ARTICLE
Chryso Th Pallari, Souzana Achilleos, Annalisa Quattrocchi, John Gabel, Elena Critselis, Maria Athanasiadou, Mohammad Reza Rahmanian Haghighi, Stefania Papatheodorou, Tianyu Liu, Andreas Artemiou, Jose M Rodriguez-Llanes, Catherine M Bennett, Claudia Zimmermann, Eva Schernhammer, Natalia Bustos Sierra, Reindert Ekelson, Jackeline Lobato, Laylla Macedo, Laust Hvas Mortensen, Julia Critchley, Lucy Goldsmith, Gleb Denissov, Nolwenn Le Meur, Levan Kandelaki, Kostas Athanasakis, Binyamin Binyaminy, Tamar Maor, Fabrizio Stracci, Giuseppe Ambrosio, Kairat Davletov, Nataliya Glushkova, Cyndy Martial, Marie Chan Sun, Terje P Hagen, Mario Chong, Manuel Barron, Błażej Łyszczarz, Ivan Erzen, Pedro Arcos Gonzalez, Bo Burström, Nataliia Pidmurniak, Olesia Verstiuk, Qian Huang, Antonis Polemitis, Andreas Charalambous, Christiana A Demetriou
INTRODUCTION: To examine the impact of the COVID-19 pandemic on mortality, we estimated excess all-cause mortality in 24 countries for 2020 and 2021, overall and stratified by sex and age. METHODS: Total, age-specific and sex-specific weekly all-cause mortality was collected for 2015-2021 and excess mortality for 2020 and 2021 was calculated by comparing weekly 2020 and 2021 age-standardised mortality rates against expected mortality, estimated based on historical data (2015-2019), accounting for seasonality, and long-term and short-term trends...
April 18, 2024: BMJ Global Health
https://read.qxmd.com/read/38636983/respiratory-outcomes-and-survival-after-unplanned-extubation-in-the-nicu-a-prospective-cohort-study-from-the-sepreven-trial
#39
JOURNAL ARTICLE
Helene Yager, Manon Tauzin, Xavier Durrmeyer, Darina Todorova, Laurent Storme, Thierry Debillon, Florence Casagrande, Camille Jung, Etienne Audureau, Richard Layese, Laurence Caeymaex
OBJECTIVE: To compare reintubation rates after planned extubation and unplanned extubation (UE) in patients in neonatal intensive care units (NICUs), to analyse risk factors for reintubation after UE and to compare outcomes in patients with and without UE. DESIGN: Prospective, observational study nested in a randomised controlled trial (SEPREVEN/Study on Epidemiology and PRevention of adverse EVEnts in Neonates). Outcomes were expected to be independent of the intervention tested...
April 18, 2024: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://read.qxmd.com/read/38636708/a-multicentric-randomized-controlled-phase-iii-trial-of-adaptive-and-18f-fdg-pet-guided-dose-redistribution-in-locally-advanced-head-and-neck-squamous-cell-carcinoma-artforce
#40
JOURNAL ARTICLE
Anna Liza M P de Leeuw, Jordi Giralt, Yungan Tao, Sergi Benavente, Thanh-Vân France Nguyen, Frank J P Hoebers, Ann Hoeben, Chris H J Terhaard, Lip Wai Lee, Signe Friesland, Roel J H M Steenbakkers, Lisa Tans, Jolien Heukelom, Mutamba T Kayembe, Simon R van Kranen, Harry Bartelink, Coen R N Rasch, Jan-Jakob Sonke, Olga Hamming-Vrieze
BACKGROUND AND PURPOSE: This multicenter randomized phase III trial evaluated whether locoregional control of patients with LAHNSCC could be improved by fluorodeoxyglucose-positron emission tomography (FDG-PET)-guided dose-escalation while minimizing the risk of increasing toxicity using a dose-redistribution and scheduled adaptation strategy. MATERIALS AND METHODS: Patients with T3-4-N0-3-M0 LAHNSCC were randomly assigned (1:1) to either receive a dose distribution ranging from 64-84 Gy/35 fractions with adaptation at the 10thfraction (rRT) or conventional 70 Gy/35 fractions (cRT)...
April 16, 2024: Radiotherapy and Oncology
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