Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#1
JOURNAL ARTICLE
Soroush Mirkiani, Carly L O'Sullivan, David A Roszko, Pouria Faridi, David S Hu, Dirk G Everaert, Amirali Toossi, Ryan Kang, Tongzhou Fang, Neil Tyreman, Ashley N Dalrymple, Kevin Robinson, Richard R E Uwiera, Hamid Shah, Richard Fox, Peter E Konrad, Vivian K Mushahwar
OBJECTIVE: The goal of this study was to assess the safety of mapping spinal cord locomotor networks using penetrating stimulation microelectrodes in Yucatan minipigs (YMPs) as a clinically translational animal model. METHODS: Eleven YMPs were trained to walk up and down a straight line. Motion capture was performed, and electromyographic (EMG) activity of hindlimb muscles was recorded during overground walking. The YMPs underwent a laminectomy and durotomy to expose the lumbar spinal cord...
May 10, 2024: Journal of Neurosurgery. Spine
#2
JOURNAL ARTICLE
Z Y Zhang, L T Yang, Q Yue, K J Kang, Y J Li, H P An, Greeshma C, J P Chang, Y H Chen, J P Cheng, W H Dai, Z Deng, C H Fang, X P Geng, H Gong, Q J Guo, T Guo, X Y Guo, L He, S M He, J W Hu, H X Huang, T C Huang, L Jiang, S Karmakar, H B Li, H Y Li, J M Li, J Li, Q Y Li, R M J Li, X Q Li, Y L Li, Y F Liang, B Liao, F K Lin, S T Lin, J X Liu, S K Liu, Y D Liu, Y Liu, Y Y Liu, H Ma, Y C Mao, Q Y Nie, J H Ning, H Pan, N C Qi, J Ren, X C Ruan, M K Singh, T X Sun, C J Tang, Y Tian, G F Wang, J Z Wang, L Wang, Q Wang, Y F Wang, Y X Wang, H T Wong, S Y Wu, Y C Wu, H Y Xing, R Xu, Y Xu, T Xue, Y L Yan, N Yi, C X Yu, H J Yu, J F Yue, M Zeng, Z Zeng, B T Zhang, F S Zhang, L Zhang, Z H Zhang, J Z Zhao, K K Zhao, M G Zhao, J F Zhou, Z Y Zhou, J J Zhu
Recently a dark matter-electron (DM-electron) paradigm has drawn much attention. Models beyond the standard halo model describing DM accelerated by high energy celestial bodies are under intense examination as well. In this Letter, a velocity components analysis (VCA) method dedicated to swift analysis of accelerated DM-electron interactions via semiconductor detectors is proposed and the first HPGe detector-based accelerated DM-electron analysis is realized. Utilizing the method, the first germanium based constraint on sub-GeV solar reflected DM-electron interaction is presented with the 205...
April 26, 2024: Physical Review Letters
#3
JOURNAL ARTICLE
Charles De Guzman, Chloe A Thomas, Lynn Wiwanto, Dier Hu, Jose Henriquez-Rivera, Lily Gage, Jaclyn C Perreault, Emily Harris, Charlotte Rastas, Danny McCormick, Adam Gaffney
BACKGROUND: Although federal legislation made COVID-19 vaccines free, inequities in access to medical care may affect vaccine uptake. OBJECTIVE: To assess whether health care access was associated with uptake and timeliness of COVID-19 vaccination in the United States. DESIGN: A cross-sectional study. SETTING: 2021 National Health Interview Survey (Q2-Q4). SUBJECTS: In all, 21,532 adults aged≥18 were included in the study...
June 1, 2024: Medical Care
#4
JOURNAL ARTICLE
Chunjing Hu, Xiaobing Lou, Xiang Wu, Jingxin Li, Zhenhuang Su, Nian Zhang, Jiong Li, Bingwen Hu, Chao Li
Integrating anion-redox capacity with orthodox cation-redox capacity is deemed as a promising solution for high-energy-density battery cathodes surmounting the present technical bottlenecks. However, the evolution of oxidized oxygen species during the electrochemical or chemical process easily jeopardizes the reversibility of oxygen redox and remains poorly understood. Herein, we showcase the gradual conversion of the π-interacting oxygen (localized hole states on O) to the σ-interacting oxygen upon resting at a high voltage for P3-type Na0...
May 10, 2024: ACS Nano
#5
JOURNAL ARTICLE
Xiehui Chen, Zhanke Wang, Jiaxuan Wang, Zhongzhen Zhu, Chunxin Li, Tian Hu
We proposed that the pharynx, as a common organ of the respiratory and digestive tracts, may be a respiratory and digestive tract cross cryptic transmission pathway for 2019-nCoV infection from the nasal cavities to the pharynx and lung, then to nasal cavities by aerosol (respiratory route) to the pharynx and the gastrointestinal tract, then to the oral cavity by feces (fecal-oral route) and to pharynx, lungs, or gastrointestinal tract.
April 30, 2024: Journal of Infection in Developing Countries
#6
JOURNAL ARTICLE
Xueyao Wang, Xuyang Hu, Zhengjun Qu, Ting Sun, Lihui Huang, Shimin Xu
Molybdenum disulfide (MoS2 )-based materials for piezocatalysis are unsatisfactory due to their low actual piezoelectric coefficient and poor electrical conductivity. Herein, 1T/3R phase MoS2 grown in situ on multiwalled carbon nanotubes (MWCNTs) was proposed. MoS2 @MWCNTs exhibited the interwoven morphology of thin nanoflowers and tubes, and the piezoelectric response of MoS2 @MWCNTs was 4.07 times higher than that of MoS2 via piezoresponse force microscopy (PFM) characterization. MoS2 @MWCNTs exhibited superior activity with a 91% degradation rate of norfloxacin (NOR) after actually working 24 min (as for rhodamine B, reached 100% within 18 min) by pulse-mode ultrasonic vibration-triggered piezocatalysis...
May 10, 2024: ACS Applied Materials & Interfaces
#7
JOURNAL ARTICLE
Mengmeng Xiong, Ying Zhang, Huan Zhang, Qiaoqiao Shao, Qifan Hu, Junjie Ma, Yiqun Wan, Lan Guo, Xin Wan, Haitao Sun, Zhongyi Yuan, Hao Wan
Aggressive nature of colon cancer and current imprecise therapeutic scenarios simulate the development of precise and effective treatment strategies. To achieve this, a tumor environment-activated photosensitized biomimetic nanoplatform (PEG2000 -SiNcTI-Ph/CpG-ZIF-8@CM) is fabricated by encapsulating metal-organic framework loaded with developed photosensitizer PEG2000 -SiNcTI-Ph and immunoadjuvant CpG oligodeoxynucleotide within fusion cell membrane expressing programmed death protein 1 (PD-1) and cluster of differentiation 47 (CD47)...
May 10, 2024: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
#8
JOURNAL ARTICLE
Yongjie Xiang, Xiaowen Xie, Huanran Zhong, Fei Xiao, Ruijie Xie, Biyuan Liu, Hao Guo, Di Hu, Pan Zhang, Haibao Huang
Advanced oxidation process (AOP) wet scrubber is a powerful and clean technology for organic pollutant treatment but still presents great challenges in removing the highly toxic and hydrophobic volatile organic compounds (VOCs). Herein, we elaborately designed a bifunctional cobalt sulfide (CoS2 )/activated carbon (AC) catalyst to activate peroxymonosulfate (PMS) for efficient toxic VOC removal in an AOP wet scrubber. By combining the excellent VOC adsorption capacity of AC with the highly efficient PMS activation activity of CoS2 , CoS2 /AC can rapidly capture VOCs from the gas phase to proceed with the SO4 •- and HO• radical-induced oxidation reaction...
May 10, 2024: Environmental Science & Technology
#9
JOURNAL ARTICLE
Di Zhu, Yu Lu, Zhanchao Yan, Qian Deng, Bo Hu, Yinsong Wang, Wenjing Wang, Yanming Wang, Yuji Wang
Triple-negative breast cancer is a highly aggressive and heterogeneous breast cancer subtype characterized by early metastasis, poor prognosis, and high recurrence. Targeting histone citrullination-mediated chromatin dysregulation to induce epigenetic alterations shows great promise in TNBC therapy. We report the synthesis, optimization, and evaluation of a novel series of β-carboline-derived peptidyl arginine deiminase 4 inhibitors that exhibited potent inhibition of TNBC cell proliferation. The most outstanding PAD4 inhibitor, compound 28 , hindered the PAD4-H3cit-NET signaling pathway and inhibited the growth of solid tumors and pulmonary metastatic nodules in the 4T1 in situ mouse model...
May 10, 2024: Journal of Medicinal Chemistry
#10
JOURNAL ARTICLE
Zequn Ma, Xiantong Hu, Xiangming Li, Qi An, Yi Zhang, Chunxian Guo, Yantao Zhao, Yihe Zhang
Guided bone regeneration (GBR) membranes that reside at the interface between the bone and soft tissues for bone repair attract increasing attention, but currently developed GBR membranes suffer from relatively poor osteogenic and antibacterial effects as well as limited mechanical property and biodegradability. We present here the design and fabrication of a bifunctional Janus GBR membrane based on a shear flow-driven layer by a layer self-assembly approach. The Janus GBR membrane comprises a calcium phosphate-collagen/polyethylene glycol (CaP@COL/PEG) layer and a chitosan/poly(acrylic acid) (CHI/PAA) layer on different sides of a collagen membrane to form a sandwich structure...
May 10, 2024: ACS Biomaterials Science & Engineering
#11
JOURNAL ARTICLE
Xiaoya Tong, Yan Ran, Jingjing Da, Ying Hu, Jing Yuan, Yan Rui
BACKGROUND: Arteriovenous fistula stenosis can directly lead to the formation of autologous arteriovenous fistula aneurysms (AVFAs), but the coexistence of true and pseudoaneurysms is relatively rare. The coexistence of true and pseudoaneurysms increases the risk of rupture of the arteriovenous fistula and complicates subsequent surgical intervention, potentially posing a threat to the patient's life, and thus requires significant attention. CASE PRESENTATION: The patient presented with arteriovenous fistula (AVF) after hemodialysis 6 years ago...
May 10, 2024: Medicine (Baltimore)
#12
JOURNAL ARTICLE
Chengxi Han, Shuo Liu, Yunfeng Ji, Yuhua Hu, Jingwen Zhang
CDCA3, a cell cycle regulator gene that plays a catalytic role in many tumors, was initially identified as a regulator of cell cycle progression, specifically facilitating the transition from the G2 phase to mitosis. However, its role in glioma remains unknown. In this study, bioinformatics analyses (TCGA, CGGA, Rembrandt) shed light on the upregulation and prognostic value of CDCA3 in gliomas. It can also be included in a column chart as a parameter predicting 3- and 5-year survival risk (C index = 0.86). According to Gene Set Enrichment Analysis and gene ontology analysis, the biological processes of CDCA3 are mainly concentrated in the biological activities related to cell cycle such as DNA replication and nuclear division...
May 10, 2024: Medicine (Baltimore)
#13
JOURNAL ARTICLE
Xiang Zhang, Chunzi Zhou, Jingwen Hu, Jingwen Hu, Yueping Ding, Shiqi Chen, Xu Wang, Lei Xu, Zhijun Gou, Shuqiao Zhang, Weiqun Shi
BACKGROUND: nonalcoholic fatty liver disease (NAFLD) is a common liver disease affecting the global population and its impact on human health will continue to increase. Genetic susceptibility is an important factor influencing its onset and progression, and there is a lack of reliable methods to predict the susceptibility of normal populations to NAFLD using appropriate genes. METHODS: RNA sequencing data relating to nonalcoholic fatty liver disease was analyzed using the "limma" package within the R software...
May 10, 2024: Medicine (Baltimore)
#14
REVIEW
Yi-Ling Dai, Ling Xiao, Zhen Pan, Guo-Qian He, Ju Gao, Xia Guo, Zhuo Huang
RATIONALE: Paraneoplastic neurological syndrome with anti-Hu antibody (Hu-PNS) is a neurological disorder that occur in patients with malignancy. The syndrome has a wide range of presentations and can present before diagnosis of primary malignancy. Familiarity with these paraneoplastic neurological syndromes can help early recognition and take appropriate regimens. PATIENTS CONCERNS: Diagnosis and treatment of Hu-PNS. DIAGNOSES: This is retrospective study that analyzed the clinical data of this case...
May 10, 2024: Medicine (Baltimore)
#15
JOURNAL ARTICLE
Shi-Di Yang, Meng-Zong Chen, Deng-Feng Yang, Shao-Bo Hu, Dong-Dong Zheng
To screen immune-related prognostic biomarkers in low-grade glioma (LGG), and reveal the potential regulatory mechanism. The differential expressed genes (DEGs) between alive and dead patients were initially identified, then the key common genes between DEGs and immune-related genes were obtained. Regarding the key DEGs associated with the overall survival (OS), their clinical value was assessed by Kaplan-Meier, RCS, logistic regression, ROC, and decision curve analysis methods. We also assessed the role of immune infiltration on the association between key DEGs and OS...
May 10, 2024: Medicine (Baltimore)
#16
JOURNAL ARTICLE
Yongqiang Zhang, Shanshan Hu, Yiyao Deng, Zhi Yang, Jing Yuan
RATIONALE: Thrombotic thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathy caused by reduced activity of the von Willebrand factor-cleaving protease (ADAMTS13), which can be life-threatening. The patient reported in this case study also had concurrent Sjögren syndrome and renal impairment, presenting multiple symptoms and posing a great challenge in treatment. PATIENT CONCERNS: A 25-year-old woman in the postpartum period visited the hospital due to indifference in consciousness for more than 1 day following cesarean section 8 days prior...
May 10, 2024: Medicine (Baltimore)
#17
JOURNAL ARTICLE
Xun Li, Hui Hu, Tian Tan, Mengjing Sun, Yuwen Bao, Zhongbing Huang, Sohail Muhammad, Xiaohong Xia, Yun Gao
Detection of leaks of flammable methane (CH4 ) gas in a timely manner can mitigate health, safety, and environmental risks. Zinc oxide (ZnO), a polar semiconductor with controllable surface defects, is a promising material for gas sensing. In this study, Ag-Ru co-doped into self-assembled ZnO nanorod arrays (ZnO NRs) was prepared by a one-step hydrothermal method. The Ag-Ru co-doped sample shows a good hydrophobic property as a result of its particular microstructure, which results in high humidity resistance...
May 10, 2024: ACS Applied Materials & Interfaces
#18
JOURNAL ARTICLE
Min Zhang, Kangdi Hu, Lin Ma, Meihui Geng, Conghe Zhang, Gaifang Yao, Hua Zhang
Cysteine desulfhydrase (LCD) catalyzes the generation of the signaling molecule hydrogen sulfide (H2S) in plants. In this study, we found that H2S can inhibit tomato (Solanum lycopersicum) fruit ripening and SlWRKY6 undergoes differential protein persulfidation in SlLCD1-overexpressing leaves. Then, further study indicated that SlWRKY6 could be persulfidated by H2S at Cys396. By construction of slwrky6 mutants and SlWRKY6-OE lines, we found that SlWRKY6 positively regulates leaf senescence and fruit ripening by activating the transcription of ripening-related genes STAYGREEN 1 (SlSGR1) and Senescence-Associated Gene 12 (SlSAG12)...
May 10, 2024: Plant Physiology
#19
JOURNAL ARTICLE
Xinglei Yu, Xinzhi Zhao, Liangsheng Li, Xiao-Min Hu, Xiangmei Duan, Haidong Yuan, Chengjie Zhang
Non-Hermitian quantum metrology, an emerging field at the intersection of quantum estimation and non-Hermitian physics, holds promise for revolutionizing precision measurement. Here, we present a comprehensive investigation of non-Hermitian quantum parameter estimation in the quantum regime, with a special focus on achieving Heisenberg scaling. We introduce a concise expression for the quantum Fisher information (QFI) that applies to general non-Hermitian Hamiltonians, enabling the analysis of estimation precision in these systems...
May 10, 2024: Science Advances
#20
JOURNAL ARTICLE
Gai-Feng Hu, Ling-Bing Meng, Jianyi Li, Jiapei Xu, Hong-Xuan Xu, De-Ping Liu
RATIONALE: Myocardial fibrosis is an important pathological change that occurs during ventricular remodeling in patients with hypertension and is an important pathophysiological basis of cardiovascular disease. However, the molecular mechanism underlying this ventricular remodeling is unclear. METHODS: Bioinformatics analysis identified HLA-B and TIMP1 as hub genes in the process of myocardial fibrosis. Expression and correlation analyses of significant hub genes with ventricular remodeling were performed...
May 9, 2024: Aging
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
