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https://www.readbyqxmd.com/read/28070244/assessment-of-fetus-during-second-trimester-ultrasonography-using-hdlive-software-what-is-its-real-application-in-the-obstetrics-clinical-practice
#1
Gabriele Tonni, Gianpaolo Grisolia, Eduardo Félix Santana, Edward Araujo Júnior
AIM: To show imaging results from application of four-dimensional (4D) ultrasound lightening technique (HDlive™) in clinical obstetrics practice. METHODS: Normal and abnormal fetuses at second and third trimester of pregnancy undergoing routine scan with 4D HDlive™ (5DUS) in the rendering mode are described. Realistic features of fetal structures were provided by 5DUS in the rendering mode. Normal anatomy as well as pathology like cleft lip, hypoplastic face, micrognathia, low-set ears, corpus callosum, arthrogryposis, aortic arch, left congenital diaphragmatic hernia are highlighted in this study...
December 28, 2016: World Journal of Radiology
https://www.readbyqxmd.com/read/28043851/negative-pressure-wound-therapy-in-orthopaedic-surgery
#2
REVIEW
N Robert
Negative pressure wound therapy (NPWT) consists in applying subatmospheric pressure to a wound that is sealed off by a specially designed dressing and connected by a tube to a suction pump and drainage collection system. Skin defects are extremely common in orthopaedic and trauma surgery. NPWT is valuable across a range of indications. Proven effects include an increase in blood flow, stimulation of angiogenesis, and a decrease in wound surface area. NPWT can be used to treat post-traumatic and surgical wounds, burns, and chronic wounds such as pressure sores and ulcers...
December 30, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28026947/biodegradable-kojic-acid-based-polymers-controlled-delivery-of-bioactives-for-melanogenesis-inhibition
#3
Jonathan J Faig, Alysha Moretti, Laurie B Joseph, Yingyue Zhang, Mary Joy Nova, Kervin Smith, Kathryn E Uhrich
Kojic acid (KA) is a naturally occurring fungal metabolite that is utilized as a skin-lightener and anti-browning agent owing to its potent tyrosinase inhibition activity. While efficacious, KA's inclination to undergo pH-mediated, thermal-, and photo-degradation reduces its efficacy, necessitating stabilizing vehicles. To minimize degradation, poly(carbonate-esters) and polyesters comprised of KA and natural diacids were prepared via solution polymerization methods. In vitro hydrolytic degradation analyses revealed KA release was drastically influenced by polymer backbone composition (e...
December 27, 2016: Biomacromolecules
https://www.readbyqxmd.com/read/28012391/energy-transfer-and-colour-tunability-in-uv-light-induced-tm-3-tb-3-eu-3-znb-glasses-generating-white-light-emission
#4
V Naresh, Kiran Gupta, C Parthasaradhi Reddy, Byoung S Ham
A promising energy transfer (Tm(3+)→Tb(3+)→Eu(3+)) approach is brought forward to generate white light emission under ultraviolet (UV) light excitation for solid state lightening. Tm(3+)/Tb(3+)/Eu(3+) ions are combinedly doped in zinc borate glass system in view of understanding energy transfer process resulting in white light emission. Zinc borate (host) glass displayed optical and luminescence properties due to formation of Zn(II)x-[O(-II)]y centres in the ZnB glass matrix. At 360nm (UV) excitation, triply doped Tm(3+)/Tb(3+)/Eu(3+): ZnB glasses simultaneously shown their characteristic emission bands in blue (454nm: (1)D2→(3)F4), green (547nm: (5)D4→(7)F5) and red (616nm: (5)D0→(7)F2) regions...
December 15, 2016: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28006662/potent-anticancer-activity-of-a-new-bismuth-iii-complex-against-human-lung-cancer-cells
#5
Ruizhuo Ouyang, Yang Yang, Xiao Tong, Kai Feng, Yaoqin Yang, Huihong Tao, Xiaoshen Zhang, Tianyu Zong, Penghui Cao, Fei Xiong, Ning Guo, Yuhao Li, Yuqing Miao, Shuang Zhou
The aim of this work is experimental study of an interesting bismuth(III) complex derived from pentadentate 2,6-pyridinedicarboxaldehyde bis((4)N-methylthiosemicarbazone), [BiL(NO3)2]NO3 {L=2,6-pyridinedicarboxaldehyde bis((4)N-methylthiosemicarbazone)}. A series of in vitro biological studies indicate that the newly prepared [BiL(NO3)2]NO3 greatly suppressed colony formation, migration and significantly induced apoptosis of human lung cancer cells A549 and H460, but did not obviously decrease the cell viability of non-cancerous human lung fibroblast (HLF) cell line, showing much higher anticancer activities than its parent ligands, especially with half maximum inhibitory concentration (IC50) <3...
December 11, 2016: Journal of Inorganic Biochemistry
https://www.readbyqxmd.com/read/28002235/allergic-contact-dermatitis-due-to-3-o-ethyl-l-ascorbic-acid-contained-in-skin-lightening-cosmetics
#6
Ana M Victoria-Martínez, Pedro Mercader-García
No abstract text is available yet for this article.
December 20, 2016: Dermatitis
https://www.readbyqxmd.com/read/27943305/use-of-skin-lightening-products-among-selected-urban-communities-in-accra-ghana
#7
Margaret Lartey, Francis D Krampa, Mubarak Abdul-Rahman, Naa L Quarcoo, Phaedra Yamson, Paa G Hagan, Yao Tettey, Richard Gyasi, Andrew A Adjei
BACKGROUND: The practice of skin lightening has been reported from North America, Europe, Asia, and Africa. In literature, some prevalence rates exceed 50%, and both sexes are involved. Common agents used include hydroquinone, mercury, corticosteroids, and caustic agents. The agents are easily accessible and affordable with very little regulation. Cutaneous and systemic side effects occur but do not appear to be a deterrent, as the notion of light skin as a surrogate for beauty is strong...
January 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/27919275/rayyan-a-web-and-mobile-app-for-systematic-reviews
#8
Mourad Ouzzani, Hossam Hammady, Zbys Fedorowicz, Ahmed Elmagarmid
BACKGROUND: Synthesis of multiple randomized controlled trials (RCTs) in a systematic review can summarize the effects of individual outcomes and provide numerical answers about the effectiveness of interventions. Filtering of searches is time consuming, and no single method fulfills the principal requirements of speed with accuracy. Automation of systematic reviews is driven by a necessity to expedite the availability of current best evidence for policy and clinical decision-making. We developed Rayyan ( http://rayyan...
December 5, 2016: Systematic Reviews
https://www.readbyqxmd.com/read/27913685/novel-biomarkers-in-kidney-disease-roles-for-cilia-wnt-signalling-and-atmin-in-polycystic-kidney-disease
#9
REVIEW
Paraskevi Goggolidou, Patricia D Wilson
Biomarkers, the measurable indicators of biological conditions, are fast becoming a popular approach in providing information to track disease processes that could lead to novel therapeutic interventions for chronic conditions. Inherited, chronic kidney disease affects millions of people worldwide and although pharmacological treatments exist for some conditions, there are still patients whose only option is kidney dialysis and kidney transplantation. In the past 10 years, certain chronic kidney diseases have been reclassified as ciliopathies...
December 15, 2016: Biochemical Society Transactions
https://www.readbyqxmd.com/read/27911217/laser-toning-for-melasma-a-single-center-experience-with-38-970-cases
#10
Brian Tian
Melasma is a common pigmentation in Asian women. Lasers have been used to lighten melasma, although with variable outcomes and complications. In Asia, laser toning is a common technique used to safely lighten melasma. However, no large studies have been performed to validate efficacy. In our study, we demonstrate that in 38,970 Asian women, at least 35,890 patients (92.1%) had noticeable to excellent improvement in their melasma.
December 2, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27888376/laser-flare-cell-photometer-principle-and-significance-in-clinical-and-basic-ophthalmology
#11
REVIEW
Mitsuru Sawa
A slit-lamp examination is an indispensable and essential clinical evaluation method in ophthalmology, but, it is qualitative subjective. To complement its weaknesses in making a quantitative evaluation of flare intensity and number of cells in the aqueous humor in the eye, we invented the laser flare-cell photometer in 1988. The instrument enables a non-invasive quantitative evaluation of flare intensity and number of cells in the aqueous with good accuracy and repeatability as well as maneuverability equal to slit-lamp microscopy...
November 25, 2016: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/27862009/development-and-validation-of-an-ultraviolet-visible-uv-vis-spectrophotometric-method-for-determination-of-phenylethyl-resorcinol-in-new-topical-nanoemulsions
#12
Liang Hong, Dan Han, Ming-Xin Li, Pei Zhang, Chen-Guang Liu
OBJECTIVE: To develop a rapid, simple and efficient Ultraviolet-visible (UV-Vis) spectrophotometric method for the quantification of phenylethyl resorcinol (PR), a potent skin-lightening agent, incorporated into new topical nanoemulsions, and to validate this method according to International Commission for Harmonization (ICH) guidelines. METHODS: UV-Vis spectrophotometric method for quantification of PR in new topical nanoemulsions was developed and validated in terms of specificity, linearity, sensitivity, precision, and accuracy...
November 9, 2016: International Journal of Cosmetic Science
https://www.readbyqxmd.com/read/27853546/adaptive-phenotypic-response-to-climate-enabled-by-epigenetics-in-a-k-strategy-species-the-fish-leucoraja-ocellata-rajidae
#13
Jackie Lighten, Danny Incarnato, Ben J Ward, Cock van Oosterhout, Ian Bradbury, Mark Hanson, Paul Bentzen
The relative importance of genetic versus epigenetic changes in adaptive evolution is a hotly debated topic, with studies showing that some species appear to be able to adapt rapidly without significant genetic change. Epigenetic mechanisms may be particularly important for the evolutionary potential of species with long maturation times and low reproductive potential ('K-strategists'), particularly when faced with rapidly changing environmental conditions. Here we study the transcriptome of two populations of the winter skate (Leucoraja ocellata), a typical 'K-strategist', in Atlantic Canada; an endemic population in the southern Gulf of St Lawrence and a large population on the Scotian Shelf...
October 2016: Royal Society Open Science
https://www.readbyqxmd.com/read/27851907/the-depigmenting-effect-of-natural-resorcinol-type-polyphenols-kuwanon-o-and-sanggenon-t-from-the-roots-of-morus-australis
#14
Shuting Hu, Zongping Zheng, Feng Chen, Mingfu Wang
ETHNOPHARMACOLOGICAL RELEVANCE: Morus australis, one of the major Morus species growing in East Asia, is rich in phenolic compounds. The extract of M. australis has been used as skin whitening components for a long period. The action mechanisms of its principal constituents are still unclear. This study aims to evaluate the skin lightening effects of phenolic compounds extracted from the root of M. australis in different melanocyte systems and artificial skin models. MATERIALS AND METHODS: The depigmenting effect of resorcinol type polyphenols (RTPs) from the root extract of M...
January 4, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27829416/tyrosinase-inhibition-and-antioxidant-properties-of-asphodelus-microcarpus-extracts
#15
Amalia Di Petrillo, Ana Maria González-Paramás, Benedetta Era, Rosaria Medda, Francesca Pintus, Celestino Santos-Buelga, Antonella Fais
BACKGROUND: Asphodelus microcarpus belongs to the family Liliaceae that include several medicinal plants. In the traditional medicine plants of the genus Asphodelus are used to treat skin disorders such as ectodermal parasites, psoriasis, microbial infection and for lightening freckles. In order to find novel skin depigmenting agents, the present work was carry out to evaluate antioxidant activity and tyrosinase inhibitory potential of leaves, flowers and tubers extracts of A. microcarpus...
November 9, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27826660/-evaluation-of-the-decision-aid-entscheidungshilfe-prostatakrebs-from-the-patients-view-results-from-the-first-three-months
#16
C Groeben, A Ihrig, T Hölscher, T Krones, E Kessler, S Kliesch, C Wülfing, R Koch, M P Wirth, J Huber
BACKGROUND: The decision aid "Entscheidungshilfe Prostatakrebs" is available online free of charge since June 2016. It is designed to support patients with their treatment decision-making and to lighten the burden on their treating urologists. This study evaluates usage data from the first 3 months. MATERIALS AND METHODS: The ICHOM standard set was applied to allow a personalised presentation and to collect relevant data for subsequent counselling. Additionally, personal preferences and psychological burden were assessed amongst others...
December 2016: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/27801448/characterization-and-utilization-of-prussian-blue-and-its-pigments
#17
Fernande Grandjean, Louise Samain, Gary J Long
This review deals with our long-range goal of determining why the Prussian blue pigments, typically either the "soluble" KFe(III)[Fe(II)(CN)6]·xH2O or the alternative "insoluble" Fe[Fe(II)(CN)6]3·xH2O compounds, used by artists from shortly after the discovery of Prussian blue in 1704 and well into the early twentieth century, often fade when exposed to light. In order to achieve this goal it was decided that first, for comparison purposes, we had to prepare and fully characterize Prussian blues prepared by various, often commercially successful, synthetic methods...
November 1, 2016: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/27793866/dementia-epilepsy-and-polyneuropathy-in-a-mercury-exposed-patient-investigation-identification-of-an-obscure-source-and-treatment
#18
Tobias Zellner, Nicolas Zellner, Norbert Felgenhauer, Florian Eyer
We present a patient aged 54 years with early onset of dementia, epilepsy and peripheral polyneuropathy. A mercury intoxication was diagnosed in 2010, chelation therapy with 2,3-dimercaptopropane-1-sulfonate had failed. A source of exposure could not be identified. MRI showed unspecific hyperintense brain lesions in 2015. She was referred for diagnosis and treatment. Neuropsychological testing indicated severe memory loss and nerve conduction speed measurements showed chronic neurogenically changed potentials...
October 28, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27785083/overall-skin-tone-and-skin-lightening-improving-effects-with-oral-supplementation-of-lutein-and-zeaxanthin-isomers-a-double-blind-placebo-controlled-clinical-trial
#19
Vijaya Juturu, James P Bowman, Jayant Deshpande
PURPOSE: Carotenoids, especially lutein and zeaxanthin isomers (L/Zi), filter blue light and protect skin from environmental factors including high-energy sources. These carotenoids may be able to block the formation of melanin pathways, decrease cytokines, and increase antioxidants. SUBJECTS AND METHODS: This is a randomized, double-blind, placebo-controlled clinical trial over a 12-week supplementation period. Fifty healthy people (50 healthy subjects were recruited and 46 subjects completed the study) (males and females, age: 18-45 years) with mild-to-moderate dry skin were included in this study...
2016: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/27776184/deoxyarbutin-possesses-a-potent-skin-lightening-capacity-with-no-discernible-cytotoxicity-against-melanosomes
#20
Fang Miao, Ying Shi, Zhi-Feng Fan, Shan Jiang, Shi-Zheng Xu, Tie-Chi Lei
Safe and effective ingredients capable of removing undesired hyperpigmentation from facial skin are urgently needed for both pharmaceutical and cosmetic purposes. Deoxyarbutin (4-[(tetrahydro-2H-pyran-2-yl) oxy] phenol, D-Arb) is a glucoside derivative of hydroquinone. Here, we investigated the toxicity and efficacy of D-Arb at the sub-cellular level (directly on melanosomes) and skin pigmentation using in vivo and in vitro models to compare with its parent compound hydroquinone (1,4-benzenediol, HQ). At first, we examined the ultrastructural changes of melanosomes in hyperpigmented guinea pig skin induced by 308-nm monochromatic excimer lightand/or treated with HQ and D-Arb using transmission electron microscopy...
2016: PloS One
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