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https://www.readbyqxmd.com/read/29168411/primary-healthcare-policy-implementation-in-the-eastern-mediterranean-region-experiences-of-six-countries
#1
Chris van Weel, Faisal Alnasir, Taghreed Farahat, Jinan Usta, Mona Osman, Mariam Abdulmalik, Nagwa Nashat, Wadeia Mohamed Alsharief, Salwa Sanousi, Hassan Saleh, Mohammed Tarawneh, Felicity Goodyear-Smith, Amanda Howe, Ryuki Kassai
BACKGROUND: Primary healthcare (PHC) is essential for equitable access and cost-effective healthcare. This makes PHC a key factor in the global strategy for universal health coverage (UHC). Implementing PHC requires an understanding of the health system under prevailing circumstances, but for most countries, no data are available. OBJECTIVES: This paper describes and analyses the health systems of Bahrain, Egypt, Lebanon, Qatar, Sudan and the United Arab Emirates, in relation to PHC...
November 23, 2017: European Journal of General Practice
https://www.readbyqxmd.com/read/29167666/first-year-of-israeli-newborn-screening-for-severe-combined-immunodeficiency-clinical-achievements-and-insights
#2
Erez Rechavi, Atar Lev, Amos J Simon, Tali Stauber, Suha Daas, Talia Saraf-Levy, Arnon Broides, Amit Nahum, Nufar Marcus, Suhair Hanna, Polina Stepensky, Ori Toker, Ilan Dalal, Amos Etzioni, Shlomo Almashanu, Raz Somech
Severe combined immunodeficiency (SCID), the most severe form of T cell immunodeficiency, is detectable through quantification of T cell receptor excision circles (TRECs) in dried blood spots obtained at birth. Herein, we describe the results of the first year of the Israeli SCID newborn screening (NBS) program. This important, life-saving screening test is available at no cost for every newborn in Israel. Eight SCID patients were diagnosed through the NBS program in its first year, revealing an incidence of 1:22,500 births in the Israeli population...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29157658/continuous-ambulatory-hand-force-monitoring-during-manual-materials-handling-using-instrumented-force-shoes-and-an-inertial-motion-capture-suit
#3
G S Faber, A S Koopman, I Kingma, C C Chang, J T Dennerlein, J H van Dieën
Hand forces (HFs) are commonly measured during biomechanical assessment of manual materials handling; however, it is often a challenge to directly measure HFs in field studies. Therefore, in a previous study we proposed a HF estimation method based on ground reaction forces (GRFs) and body segment accelerations and tested it with laboratory equipment: GFRs were measured with force plates (FPs) and segment accelerations were measured using optical motion capture (OMC). In the current study, we evaluated the HF estimation method based on an ambulatory measurement system, consisting of inertial motion capture (IMC) and instrumented force shoes (FSs)...
October 25, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29154755/ribosome-surface-properties-may-impose-limits-on-the-nature-of-the-cytoplasmic-proteome
#4
Paul E Schavemaker, Wojciech M Śmigiel, Bert Poolman
Much of the molecular motion in the cytoplasm is diffusive, which possibly limits the tempo of processes. We studied the dependence of protein mobility on protein surface properties and ionic strength. We used surface-modified fluorescent proteins (FPs) and determined their translational diffusion coefficients (D) in the cytoplasm of Escherichia coli, Lactococcus lactis and Haloferax volcanii. We find that in E. coliD depends on the net charge and its distribution over the protein, with positive proteins diffusing up to 100-fold slower than negative ones...
November 20, 2017: ELife
https://www.readbyqxmd.com/read/29152534/automated-mediastinal-lymph-node-detection-from-ct-volumes-based-on-intensity-targeted-radial-structure-tensor-analysis
#5
Hirohisa Oda, Kanwal K Bhatia, Masahiro Oda, Takayuki Kitasaka, Shingo Iwano, Hirotoshi Homma, Hirotsugu Takabatake, Masaki Mori, Hiroshi Natori, Julia A Schnabel, Kensaku Mori
This paper presents a local intensity structure analysis based on an intensity targeted radial structure tensor (ITRST) and the blob-like structure enhancement filter based on it (ITRST filter) for the mediastinal lymph node detection algorithm from chest computed tomography (CT) volumes. Although the filter based on radial structure tensor analysis (RST filter) based on conventional RST analysis can be utilized to detect lymph nodes, some lymph nodes adjacent to regions with extremely high or low intensities cannot be detected...
October 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/29140924/the-association-between-pain-and-frailty-among-chinese-community-dwelling-older-adults-depression-as-a-mediator-and-its-interaction-with-pain
#6
Xiaoyu Tian, Cuili Wang, Xiaoxia Qiao, Na Liu, Lijuan Dong, Mary Butler, Huaxin Si, Yaru Jin
Pain and frailty are both prevalent and have severe health impacts among older adults. We conducted a cross-sectional observational study to examine the association between pain and frailty, and depression as a mediator and its interaction with pain on frailty among 1788 Chinese community-dwelling older adults. Physical frailty, pain intensity and depressive symptoms were assessed using the Frailty Phenotype, the revised Faces Pain Scale (FPS-R), and the 5-item Geriatric Depression Scale (GDS-5), respectively...
November 13, 2017: Pain
https://www.readbyqxmd.com/read/29139264/-construction-of-cell-factories-for-high-production-of-nerolidol-in-saccharomyces-cerevisiae
#7
Li-Li Zhang, Xiao-Lin Ma, Dong Wang, Peng Yu, Lu-Qi Huang, Xue-Li Zhang, Zhu-Bo Dai
Nerolidol is an important constituent of terpenoid essential oil and has excellent anti-tumor, anti-bacterial, and anti-oxidative properties. For realizing heterogenous production of nerolidol, our research firstly integrated the codon-optimized Actinidia sinensis nerolidol synthase gene (NES) into the terpenoid chassis strain FPP-001, and obtained NES-001 that could produce 2.71 mg•L⁻¹ nerolidol. Then, the N-terminal of the NES was fused with FPS by linker peptide GGGS. With this strategy, nerolidol production improved by 59...
August 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29135450/influence-of-acquisition-frame-rate-and-video-compression-techniques-on-pulse-rate-variability-estimation-from-vppg-signal
#8
Luca Cerina, Luca Iozzia, Luca Mainardi
In this paper, common time- and frequency-domain variability indexes obtained by pulse rate variability (PRV) series extracted from video-photoplethysmographic signal (vPPG) were compared with heart rate variability (HRV) parameters calculated from synchronized ECG signals. The dual focus of this study was to analyze the effect of different video acquisition frame-rates starting from 60 frames-per-second (fps) down to 7.5 fps and different video compression techniques using both lossless and lossy codecs on PRV parameters estimation...
November 14, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/29129866/determination-of-trace-fission-products-associated-with-thorium-and-hcl-matrix-by-inductively-coupled-plasma-mass-spectrometry-after-anion-exchange-separation
#9
Shuhua He, Mumei Chen, Zheng Li, Haixia Cong, Lan Zhang, Qinnuan Li
For the determination of μg-mg L(-1) of FPs in 100 g L(-1) of thorium matrix with HCl medium, a method, including anion-exchange pre-separation, evaporation and inductively coupled plasma mass spectrometry (ICP-MS) measurement, was developed. The procedure parameters, such as the matrix effect of thorium, the acidity of separation, the elution curve of thorium and FPs and the temperature of evaporation were optimized by batch equilibration, column elution and evaporation experiments. It was found that the average recovery of the FPs was in the range 80 - 110%, and the RSD values were in the range 2 - 15% utilizing prior anion exchange separation of FPs from thorium samples...
2017: Analytical Sciences: the International Journal of the Japan Society for Analytical Chemistry
https://www.readbyqxmd.com/read/29129121/the-validity-and-intra-tester-reliability-of-markerless-motion-capture-to-analyse-kinematics-of-the-bmx-supercross-gate-start
#10
Josephine Grigg, Eric Haakonssen, Evelyne Rathbone, Robin Orr, Justin W L Keogh
The aim of this study was to quantify the validity and intra-tester reliability of a novel method of kinematic measurement. The measurement target was the joint angles of an athlete performing a BMX Supercross (SX) gate start action through the first 1.2 s of movement in situ on a BMX SX ramp using a standard gate start procedure. The method employed GoPro® Hero 4 Silver (GoPro Inc., USA) cameras capturing data at 120 fps 720 p on a 'normal' lens setting. Kinovea 0.8.15 (Kinovea.org, France) was used for analysis...
November 13, 2017: Sports Biomechanics
https://www.readbyqxmd.com/read/29128296/sexual-and-reproductive-health-care-receipt-among-young-males-aged-15-24
#11
Arik V Marcell, Susannah E Gibbs, Nanlesta A Pilgrim, Kathleen R Page, Renata Arrington-Sanders, Jacky M Jennings, Penny S Loosier, Patricia J Dittus
PURPOSE: This study aimed to describe young men's sexual and reproductive health care (SRHC) receipt by sexual behavior and factors associated with greater SRHC receipt. METHODS: There were 427 male patients aged 15-24 who were recruited from 3 primary care and 2 sexually transmitted disease (STD) clinics in 1 urban city. Immediately after the visit, the survey assessed receipt of 18 recommended SRHC services across four domains: screening history (sexual health, STD/HIV test, family planning); laboratories (STDs/HIV); condom products (condoms/lubrication); and counseling (STD/HIV risk reduction, family planning, condoms); in addition, demographic, sexual behavior, and visit characteristics were examined...
November 8, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/29126910/impaired-oligodendrogenesis-and-myelination-by-elevated-s100b-levels-during-neurodevelopment
#12
Gisela Santos, Andreia Barateiro, Cláudio M Gomes, Dora Brites, Adelaide Fernandes
High levels of the inflammatory molecule S100B protein have been identified in sera from several perinatal inflammatory conditions involving myelin damage and associated with an adverse prognosis or the emergence of sequelea. S100B is essential for oligodendrocyte (OL) differentiation and maturation, but it remains to be established if excessive levels of released S100B upon early brain injury are deleterious in the neurodevelopmental period. Here, we investigated this possibility by evaluating how elevated S100B affects oligodendrogenesis during this period...
November 8, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/29121085/biomechanical-simulation-of-vocal-fold-dynamics-in-adults-based-on-laryngeal-high-speed-videoendoscopy
#13
Michael Döllinger, Pablo Gómez, Rita R Patel, Christoph Alexiou, Christopher Bohr, Anne Schützenberger
MOTIVATION: Human voice is generated in the larynx by the two oscillating vocal folds. Owing to the limited space and accessibility of the larynx, endoscopic investigation of the actual phonatory process in detail is challenging. Hence the biomechanics of the human phonatory process are still not yet fully understood. Therefore, we adapt a mathematical model of the vocal folds towards vocal fold oscillations to quantify gender and age related differences expressed by computed biomechanical model parameters...
2017: PloS One
https://www.readbyqxmd.com/read/29113428/visualization-of-multicolored-in-vivo-organelle-markers-for-co-localization-studies-in-oryza-sativa
#14
Sarmina Dangol, Raksha Singh, Yafei Chen, Nam-Soo Jwa
Eukaryotic cells consist of a complex network of thousands of proteins present in different organelles where organellespecific cellular processes occur. Identification of the subcellular localization of a protein is important for understanding its potential biochemical functions. In the post-genomic era, localization of unknown proteins is achieved using multiple tools including a fluorescent-tagged protein approach. Several fluorescent-tagged protein organelle markers have been introduced into dicot plants, but its use is still limited in monocot plants...
November 6, 2017: Molecules and Cells
https://www.readbyqxmd.com/read/29109385/motion-blur-free-high-speed-video-shooting-using-a-resonant-mirror
#15
Michiaki Inoue, Qingyi Gu, Mingjun Jiang, Takeshi Takaki, Idaku Ishii, Kenji Tajima
This study proposes a novel concept of actuator-driven frame-by-frame intermittent tracking for motion-blur-free video shooting of fast-moving objects. The camera frame and shutter timings are controlled for motion blur reduction in synchronization with a free-vibration-type actuator vibrating with a large amplitude at hundreds of hertz so that motion blur can be significantly reduced in free-viewpoint high-frame-rate video shooting for fast-moving objects by deriving the maximum performance of the actuator...
October 29, 2017: Sensors
https://www.readbyqxmd.com/read/29098171/the-mars-science-laboratory-msl-mast-cameras-and-descent-imager-investigation-and-instrument-descriptions
#16
Michal C Malin, Michael A Ravine, Michael A Caplinger, F Tony Ghaemi, Jacob A Schaffner, Justin N Maki, James F Bell, James F Cameron, William E Dietrich, Kenneth S Edgett, Laurence J Edwards, James B Garvin, Bernard Hallet, Kenneth E Herkenhoff, Ezat Heydari, Linda C Kah, Mark T Lemmon, Michelle E Minitti, Timothy S Olson, Timothy J Parker, Scott K Rowland, Juergen Schieber, Ron Sletten, Robert J Sullivan, Dawn Y Sumner, R Aileen Yingst, Brian M Duston, Sean McNair, Elsa H Jensen
The Mars Science Laboratory Mast camera and Descent Imager investigations were designed, built, and operated by Malin Space Science Systems of San Diego, CA. They share common electronics and focal plane designs but have different optics. There are two Mastcams of dissimilar focal length. The Mastcam-34 has an f/8, 34 mm focal length lens, and the M-100 an f/10, 100 mm focal length lens. The M-34 field of view is about 20° × 15° with an instantaneous field of view (IFOV) of 218 μrad; the M-100 field of view (FOV) is 6...
August 2017: Earth and Space Science (Hoboken, N.J.)
https://www.readbyqxmd.com/read/29095849/multimorbid-outpatients-a-high-frequency-of-fp-appointments-and-or-family-difficulties-should-alert-fps-to-the-possibility-of-death-or-acute-hospitalization-occurring-within-six-months-a-primary-care-feasibility-study
#17
Jean Yves Le Reste, Patrice Nabbe, Alice Billot Grasset, Bernard Le Floch, Pauline Grall, Jeremy Derriennic, Michele Odorico, Sophie Lalande, Delphine le Goff, Marie Barais, Benoit Chiron, Heidrun Lingner, Morgane Guillou, Pierre Barraine
BACKGROUND: The European General Practitioners Research Network (EGPRN) designed and validated a comprehensive definition of multimorbidity using a systematic literature review and qualitative research throughout Europe. This definition was tested as a model to assess death or acute hospitalization in multimorbid outpatients. OBJECTIVE: To assess which criteria in the EGPRN concept of multimorbidity could detect outpatients at risk of death or acute hospitalization in a primary care cohort at a 6-month follow-up and to assess whether a large scale cohort with FPs would be feasible...
2017: PloS One
https://www.readbyqxmd.com/read/29080824/prediction-of-arsenic-and-antimony-transporter-major-intrinsic-proteins-from-the-genomes-of-crop-plants
#18
Abul Kalam Azad, Jahed Ahmed, Md Asraful Alum, Md Mahbub Hasan, Takahiro Ishikawa, Yoshihiro Sawa
Major intrinsic proteins (MIPs), commonly known as aquaporins, transport water and non-polar small solutes. Comparing the 3D models and the primary selectivity-related motifs (two Asn-Pro-Ala (NPA) regions, the aromatic/arginine (ar/R) selectivity filter, and Froger's positions (FPs)) of all plant MIPs that have been experimentally proven to transport arsenic (As) and antimony (Sb), some substrate-specific signature sequences (SSSS) or specificity determining sites (SDPs) have been predicted. These SSSS or SDPs were determined in 543 MIPs found in the genomes of 12 crop plants; the As and Sb transporters were predicted to be distributed in noduline-26 like intrinsic proteins (NIPs), and every plant had one or several As and Sb transporter NIPs...
October 26, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29075411/effect-of-antibacterial-adhesive-approaches-on-bonding-durability-of-fiber-posts-cemented-with-self-etch-resin-cement
#19
Fereshteh Shafiei, Mahtab Memarpour, Narges Vafamand, Mahsa Mohammadi
BACKGROUND: Longevity of post-retained restoration is highly depended on bonding stability of fiber post (FP) to root dentin. This study evaluated the effect of different antibacterial/adhesive approaches on bonding durability of FPs luted into root canal with a self-etch cement. MATERIAL AND METHODS: Seventy-two human maxillary central incisor roots were divided into six groups after endodontic treatment, based on the antibacterial/adhesive treatments as follows: 1)ED primer II (ED, control); 2) Clearfil Protect Bond (PB); 3) 2% chlorhexidine (CH) pretreatment + ED primer II (CH+ED); 4) CH-incorporated into ED primer II (CH in ED); 5) CH pretreatment + Clearfil SE Bond (CH+SE); and 6)CH-incorporated into SE primer (CH in SE)...
September 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29074842/frequency-selection-rule-for-high-definition-and-high-frame-rate-lissajous-scanning
#20
Kyungmin Hwang, Yeong-Hyeon Seo, Jinhyo Ahn, Pilhan Kim, Ki-Hun Jeong
Lissajous microscanners are very attractive in compact laser scanning applications such as endomicroscopy or pro-projection display owing to high mechanical stability and low operating voltages. The scanning frequency serves as a critical factor for determining the scanning imaging quality. Here we report the selection rule of scanning frequencies that can realize high definition and high frame-rate (HDHF) full-repeated Lissajous scanning imaging. The fill factor (FF) monotonically increases with the total lobe number of a Lissajous curve, i...
October 26, 2017: Scientific Reports
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