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https://www.readbyqxmd.com/read/27902866/bacterial-community-collapse-a-meta-analysis-of-the-sinonasal-microbiota-in-chronic-rhinosinusitis
#1
Brett Wagner Mackenzie, David W Waite, Michael Hoggard, Richard G Douglas, Michael W Taylor, Kristi Biswas
Chronic rhinosinusitis (CRS) is a common, debilitating condition characterized by long-term inflammation of the nasal cavity and paranasal sinuses. The role of the sinonasal bacteria in CRS is unclear. We conducted a meta-analysis combining and reanalyzing published bacterial 16S rRNA sequence data to explore differences in sinonasal bacterial community composition and predicted function between healthy and CRS affected subjects. The results identify the most abundant bacteria across all subjects as Staphylococcus, Propionibacterium, Corynebacterium, Streptococcus, and an unclassified lineage of Actinobacteria...
November 30, 2016: Environmental Microbiology
https://www.readbyqxmd.com/read/27902761/tlr-2-recognizes-propionibacterium-acnes-camp-factor-1-from-highly-inflammatory-strains
#2
Coralie Lheure, Philippe Alain Grange, Guillaume Ollagnier, Philippe Morand, Nathalie Désiré, Sophie Sayon, Stéphane Corvec, Jöel Raingeaud, Anne-Geneviève Marcelin, Vincent Calvez, Amir Khammari, Frédéric Batteux, Brigitte Dréno, Nicolas Dupin
BACKGROUND: Propionibacterium acnes (P. acnes) is an anaerobic, Gram-positive bacteria encountered in inflammatory acne lesions, particularly in the pilosebaceous follicle. P. acnes triggers a strong immune response involving keratinocytes, sebocytes and monocytes, the target cells during acne development. Lipoteicoic acid and peptidoglycan induce the inflammatory reaction, but no P. acnes surface protein interacting with Toll-like receptors has been identified. P. acnes surface proteins have been extracted by lithium stripping and shown to induce CXCL8 production by keratinocytes...
2016: PloS One
https://www.readbyqxmd.com/read/27902675/infected-congenital-epicardial-cyst-presenting-as-acute-abdomen
#3
Timothy Dribin, Matthew D Files, Erin R Rudzinski, Ron Kaplan, Kimberly P Stone
A previously healthy 3-year-old boy presented to the emergency department with abdominal pain, fever, and emesis. Laboratory and radiologic evaluation for causes of acute abdomen were negative; however, review of the abdominal x-ray demonstrated cardiomegaly with the subsequent diagnosis of pericardial cyst by echocardiogram and computed tomography. The patient underwent surgical decompression and attempted removal of the cystic structure revealing that the cyst originated from the epicardium. His abdominal pain and fever resolved postoperatively and he completed a 3-week course of ceftriaxone for treatment of Propionibacterium acnes infected congenital epicardial cyst...
December 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27896620/antimicrobial-activity-of-topical-agents-against-propionibacterium-acnes-an-in-vitro-study-of-clinical-isolates-from-a-hospital-in-shanghai-china
#4
Ying Ma, Nanxue Zhang, Shi Wu, Haihui Huang, Yanpei Cao
This study aimed to compare the antimicrobial activities of topical agents against Propionibacterium acnes isolated from patients admitted to a hospital in Shanghai, China. The minimal inhibitory concentrations of the cultured P. acnes were determined in accordance with the Clinical and Laboratory Standards Institute. Susceptibilities to clindamycin and erythromycin were compared in terms of gender, age, disease duration, previous treatment, and disease severity. A total of 69 P. acnes strains were isolated from 98 patients (70...
November 28, 2016: Frontiers of Medicine
https://www.readbyqxmd.com/read/27894280/is-there-any-association-between-sarcoidosis-and-infectious-agents-a-systematic-review-and-meta-analysis
#5
Tiago Esteves, Gloria Aparicio, Vicente Garcia-Patos
BACKGROUND: During the last few years, investigators have debated the role that infectious agents may have in sarcoidosis pathogenesis. With the emergence of new molecular biology techniques, several studies have been conducted; therefore, we performed a meta-analysis in order to better explain this possible association. METHODS: This review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement from the Cochrane collaboration guidelines...
November 28, 2016: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/27891094/anti-acne-activity-of-italian-medicinal-plants-used-for-skin-infection
#6
Kate Nelson, James T Lyles, Tracy Li, Alessandro Saitta, Eugenia Addie-Noye, Paula Tyler, Cassandra L Quave
Propionibacterium acnes is implicated in the pathogenesis of acne vulgaris, which impacts >85% of teenagers. Novel therapies are in high demand and an ethnopharmacological approach to discovering new plant sources of anti-acne therapeutics could contribute to filling this void in effective therapies. The aims of our study were two-fold: (1) To determine if species identified in ethnopharmacological field studies as having traditional uses for skin and soft tissue infection (SSTI) exhibit significantly more activity against P...
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27890724/clinical-characteristics-and-antimicrobial-susceptibilities-of-anaerobic-bacteremia-in-an-acute-care-hospital
#7
Thean Yen Tan, Lily Siew Yong Ng, Lee Ling Kwang, Suma Rao, Li Ching Eng
: This study investigated the clinical features of anaerobic bacteraemia in an acute-care hospital, and evaluated the antimicrobial susceptibility of these isolates to commonly available antibiotics. MATERIALS & METHODS: Microbiological and epidemiological data from 2009-2011were extracted from the laboratory information system and electronic medical records. One hundred and eleven unique patient episodes consisting of 116 anaerobic isolates were selected for clinical review and antibiotic susceptibility testing...
November 24, 2016: Anaerobe
https://www.readbyqxmd.com/read/27889246/risk-factors-for-propionibacterium-acnes-infection-after-neurosurgery-a-case-control-study
#8
Yuto Haruki, Hideharu Hagiya, Yu Takahashi, Hideyuki Yoshida, Kazuki Kobayashi, Tadato Yukiue, Nobushige Tsuboi, Tetsuhiro Sugiyama
Propionibacterium acnes is increasingly known as a causative organism for post-neurosurgical infection; however, no clinical studies have examined the risk factors associated with P. acnes infections. Clinical data obtained from 14 cases of P. acnes infection and 28 controls infected with other pathogens were analyzed. Craniotomy, malignancy, and prolonged duration of operation were significantly associated with the onset of P. acnes infection. No fatal cases were reported.
November 23, 2016: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/27887875/two-stage-revision-for-infected-shoulder-arthroplasty
#9
Daniel B Buchalter, Siddharth A Mahure, Brent Mollon, Stephen Yu, Young W Kwon, Joseph D Zuckerman
BACKGROUND: Periprosthetic shoulder infections (PSIs) are challenging to treat and often result in significant patient morbidity. Without a standardized treatment protocol, PSIs are often managed similarly to periprosthetic hip and knee infections. Because 2-stage revision is the gold standard for treating periprosthetic hip and knee infections, we performed a case series and literature review to determine its effectiveness in PSIs. METHODS: We identified 19 patients (14 men) from our institution who were treated with a 2-stage revision after presenting with a PSI...
November 22, 2016: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/27887873/a-rapid-method-for-detecting-propionibacterium-acnes-in-surgical-biopsy-specimens-from-the-shoulder
#10
Scott Holmes, Ana M Pena Diaz, George S Athwal, Kenneth J Faber, David B O'Gorman
BACKGROUND: Propionibacterium (P) acnes infection of the shoulder after arthroplasty is a common and serious complication. Current detection methods for P acnes involve anaerobic cultures that require prolonged incubation periods (typically 7-14 days). We have developed a polymerase chain reaction (PCR)-restriction fragment length polymorphism (RFLP) approach that sensitively and specifically identifies P acnes in tissue specimens within a 24-hour period. METHODS: Primers were designed to amplify a unique region of the 16S rRNA gene in P acnes that contained a unique HaeIII restriction enzyme site...
November 22, 2016: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/27885956/solitary-tentorial-sarcoid-granuloma-associated-with-propionibacterium-acnes-infection-case-report
#11
Jiro Akimoto, Kenta Nagai, Daisuke Ogasawara, Yujiro Tanaka, Hitoshi Izawa, Michihiro Kohno, Keisuke Uchida, Yoshinobu Eishi
Sarcoidosis is a systemic granulomatous disease with unknown cause, which very rarely occurs exclusively in the central nervous system. The authors performed biopsy sampling of a mass that developed in the left tentorium cerebelli that appeared to be a malignant tumor. The mass was diagnosed as a sarcoid granuloma, which was confirmed with the onset of antibody reaction product against Propionibacterium acnes. Findings suggesting sarcoidosis to be an immune response to P. acnes infection have recently been reported, and they give insight for diagnosis and treatment of this disease...
November 25, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27885471/modic-changes-in-the-adjacent-vertebrae-due-to-disc-material-infection-with-propionibacterium-acnes-in-patients-with-lumbar-disc-herniation
#12
Javad Aghazadeh, Firooz Salehpour, Ehsan Ziaeii, Naghme Javanshir, Afshin Samadi, Javid Sadeghi, Farhad Mirzaei, Seyed Ahmad Naseri Alavi
INTRODUCTION: Modic changes (MCs) in vertebral bones are induced by two mechanisms of mechanical factors and infection. As Propionibacterium acnes (P. acnes) have been reported to be associated with LBP. The aim of this study is to evaluate the MCs in patients with disc herniation and positive for P. acnes. METHODS AND MATERIAL: A total of 120 patients with disc herniation surgery were enrolled into the study. The samples were excised during discectomy and then cultured in both anaerobic and aerobic incubations...
November 24, 2016: European Spine Journal
https://www.readbyqxmd.com/read/27869623/contamination-of-the-surgical-field-with-propionibacterium-acnes-in-primary-shoulder-arthroplasty
#13
Travis M Falconer, Mohammed Baba, Lisa M Kruse, Oscar Dorrestijn, Matthew J Donaldson, Margaret M Smith, Melanie C Figtree, Bernard J Hudson, Benjamin Cass, Allan A Young
BACKGROUND: Propionibacterium acnes is a common pathogen identified in postoperative shoulder infection. It has been shown to be present in culture specimens during primary shoulder arthroplasty; however, recent work has suggested that it is most likely to be a contaminant. Our aim was to identify the potential sources of contamination in shoulder arthroplasty. METHODS: Tissue swabs were obtained for microbiological analysis from consecutive patients undergoing primary shoulder arthroplasty...
October 19, 2016: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/27863184/lipase-sensitive-transfersomes-based-on-photosensitizer-polymerizable-lipid-conjugate-for-selective-antimicrobial-photodynamic-therapy-of-acne
#14
Hyung Park, Jonghwan Lee, Songhee Jeong, Byeong Nam Im, Min-Kyoung Kim, Su-Geun Yang, Kun Na
Acne vulgaris is a common skin problem affecting nearly 90% of adolescents and its development is associated with a colonization of Propionibacterium acnes (P. acnes). Although antibiotics have commonly been used to treat acne, antibiotic resistance of P. acnes is an emerging issue to be solved. In this study, a new way of photodynamic acne therapy is developed using P. acnes lipase-sensitive transfersome (DSPE-PEG-Pheo A (DPP) transfersome). For enhanced selectivity and skin penetration efficiency, DPP transfersomes are prepared from 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000], pheophorbide A (Pheo A), cholesterol, and Tween-80...
November 10, 2016: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/27861948/propionibacterium-skull-base-osteomyelitis-complicated-by-internal-carotid-artery-pseudoaneurysm
#15
Kathryn L Kreicher, Jonathan L Hatch, Shivangi Lohia, Ted A Meyer
The microbiology of skull base osteomyelitis (SBO) is evolving. We present here the first case of SBO caused by Propionibacterium acnes leading to the development of a pseudoaneurysm of the internal carotid artery. Otolaryngologists should recognize this pathogen as a potential cause of invasive temporal bone infection to optimize prompt diagnosis and treatment. Laryngoscope, 2016.
November 15, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27847503/changes-of-the-bacterial-abundance-and-communities-in-shallow-ice-cores-from-dunde-and-muztagata-glaciers-western-china
#16
Yong Chen, Xiang-Kai Li, Jing Si, Guang-Jian Wu, Li-De Tian, Shu-Rong Xiang
In this study, six bacterial community structures were analyzed from the Dunde ice core (9.5-m-long) using 16S rRNA gene cloning library technology. Compared to the Muztagata mountain ice core (37-m-long), the Dunde ice core has different dominant community structures, with five genus-related groups Blastococcus sp./Propionibacterium, Cryobacterium-related., Flavobacterium sp., Pedobacter sp., and Polaromas sp. that are frequently found in the six tested ice layers from 1990 to 2000. Live and total microbial density patterns were examined and related to the dynamics of physical-chemical parameters, mineral particle concentrations, and stable isotopic ratios in the precipitations collected from both Muztagata and Dunde ice cores...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27834859/a-precision-microbiome-approach-using-sucrose-for-selective-augmentation-of-staphylococcus-epidermidis-fermentation-against-propionibacterium-acnes
#17
Yanhan Wang, Ming-Shan Kao, Jinghua Yu, Stephen Huang, Shinta Marito, Richard L Gallo, Chun-Ming Huang
Acne dysbiosis happens when there is a microbial imbalance of the over-growth of Propionibacterium acnes (P. acnes) in the acne microbiome. In our previous study, we demonstrated that Staphylococcus epidermidis (S. epidermidis, a probiotic skin bacterium) can exploit glycerol fermentation to produce short-chain fatty acids (SCFAs) which have antimicrobial activities to suppress the growth of P. acnes. Unlike glycerol, sucrose is chosen here as a selective fermentation initiator (SFI) that can specifically intensify the fermentation activity of S...
November 9, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27833861/maxillofacial-infections-of-odontogenic-origin-epidemiological-microbiological-and-therapeutic-factors-in-an-indian-population
#18
V Yuvaraj
Odontogenic fascial space infections are commonly encountered by the oral and maxillofacial surgeon. A retrospective study of the epidemiological characteristics, microbiological analysis and treatment response to odontogenic infections treated in the oral and maxillofacial unit of a Dental school is presented. A retrospective analysis of case records of all odontogenic infections that reported to the oral and maxillofacial surgery unit in a Dental school over a period of 2 years was performed. Epidemiological data, microbiological profile and treatment responses were analysed...
December 2016: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/27829959/propionibacterium-acnes-time-to-positivity-in-standard-bacterial-culture-from-different-anatomical-sites
#19
Rasha Abdulmassih, Jina Makadia, James Como, Michelle Paulson, Zaw Min, Nitin Bhanot
BACKGROUND: Propionibacterium acnes infections are likely under-recognized and underreported. This is partly because of low clinical suspicion, perceived non-pathogenicity, or lack of adequate culture incubation time. We conducted a study to assess the optimal incubation period to recover P. acnes from specimens acquired during the workup of suspected clinical infections. METHODS: A 5-year retrospective chart review was conducted between January 2010 and December 2014 at a single tertiary-care hospital...
December 2016: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/27829389/chronic-post-operative-iris-prosthesis-endophthalmitis-in-a-patient-with-traumatic-aniridia-a-case-report
#20
Kevin C Firl, Sandra R Montezuma
BACKGROUND: Post-operative endophthalmitis is a serious complication of intraocular surgery which may present acutely or chronically. Chronic post-operative endophthalmitis is characterized by decreased visual acuity, mild pain, and low-grade uveitis several weeks or months after intraocular surgery which may be responsive to corticosteroids, but recur upon tapering. Low virulence organisms such as Propionibacterium acnes are the most common culprit organisms, and treatment most often consists of both intravitreal antibiotic injections and surgery...
November 9, 2016: BMC Ophthalmology
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