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https://www.readbyqxmd.com/read/28538949/the-follicular-skin-microbiome-in-patients-with-hidradenitis-suppurativa-and-healthy-controls
#1
Hans Christian Ring, Jonathan Thorsen, Ditte M Saunte, Berit Lilje, Lene Bay, Peter Theut Riis, Niels Larsen, Lee O'Brien Andersen, Henrik V Nielsen, Iben M Miller, Thomas Bjarnsholt, Kurt Fuursted, Gregor Borut Jemec
Importance: Although the pathogenesis of hidradenitis suppurativa (HS) remains enigmatic, several factors point to potential involvement of the cutaneous microbiome. Insight into the cutaneous microbiome in HS using next-generation sequencing may provide novel data on the microbiological diversity of the skin. Objective: To investigate the follicular skin microbiome in patients with HS and in healthy controls. Design, Setting, and Participants: This case-control study obtained punch biopsy specimens from patients with HS (lesional and nonlesional) and healthy controls between October 1, 2014, and August 1, 2016...
May 24, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28538881/efficacy-and-safety-of-superficial-chemical-peeling-in-treatment-of-active-acne-vulgaris
#2
Hassanain Al-Talib, Alyaa Al-Khateeb, Ayad Hameed, Chandrika Murugaiah
Acne vulgaris is an extremely common condition affecting the pilosebaceous unit of the skin and characterized by presence of comedones, papules, pustules, nodules, cysts, which might result in permanent scars. Acne vulgaris commonly involve adolescents and young age groups. Active acne vulgaris is usually associated with several complications like hyper or hypopigmentation, scar formation and skin disfigurement. Previous studies have targeted the efficiency and safety of local and systemic agents in the treatment of active acne vulgaris...
March 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28538877/effects-of-isotretinoin-on-the-olfactory-function-in-patients-with-acne
#3
Demet Kartal, Mehmet Yaşar, Levent Kartal, Ibrahim Özcan, Murat Borlu
Background: Isotretinoin is a synthetic analog of vitamin A. Recent studies support a role for retinoic acid in the recovery of olfactory function following injury in mice. Objective: This study aimed at determining the effect of isotretinoin on olfactory function in patients who have acne and are otherwise healthy. Methods: Forty-five patients (aged 25-40 years) with acne were included in the study. All patients underwent a rhinological examination...
March 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28537864/laboratory-tests-in-patients-treated-with-isotretinoin-occurrence-of-liver-and-muscle-abnormalities-and-failure-of-ast-and-alt-to-predict-liver-abnormality
#4
Guy F Webster, Timothy G Webster, Lorraine R Grimes
Current laboratory monitoring may not be optimal. A retrospective chart review was performed on thelaboratory results of 246 patients who were treated with isotretinoin for acne over a 9-year period. Tests obtained were CBC, lipid panel, AST, ALT, CK, GGT,and C-reactive protein. Thirty-five patients had an elevated AST and 35 of these had an elevated CK; 32 had an elevated ALT and 11 of these had an elevated CK. Thirteen patients had an elevated GGT; in 5 this was the only abnormality, whereas 8 had a GGT elevation accompanied by an elevated AST or ALT...
May 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28537860/global-skin-diseases-on-instagram-hashtags
#5
Taylor Braunberger, Jessica Mounessa, Kyle Rudningen, Cory A Dunnick, Robert P Dellavalle
Recently named one of the most influential phone applications, Instagram continues to grow in popularity [1]. Instagram consists of images and video posts, making it ideal for education and communication within the visual field of dermatology. In this study, we seek to determine the presence of dermatology-related content with regard to the most common cutaneous diseases of the world. We searched the account types and hashtags associated with the eight most common skin diseases globally as identified by the Global Burden of Disease (GBD) study by Hollenstein et al...
May 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28537857/cost-effectiveness-analysis-of-using-dermatologists-versus-pediatricians-to-treat-mild-to-moderate-acne
#6
Scott A Davis, Sebastian Himmler, Steven R Feldman
OBJECTIVE: To assess the cost-effectiveness from the payer perspective of using dermatologists versus pediatricians to treat acne in adolescents ages 10-18. METHODS: A Markov model was constructed to explore outcomes over a 2-year period from the US private payer perspective. Patients ages 10-18 with acne entered the model under the "dermatologist"and "pediatrician" conditions. In each 3-month cycle,each modeled patient received topical retinoids,benzoyl peroxide (BP), antibiotics, or no treatment,and could progress to an acne-free state or remain in an acne state...
May 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28533848/dermatology-in-ghana-a-retrospective-review-of-skin-disease-at-the-korle-bu-teaching-hospital-dermatology-clinic
#7
Brooke E Rosenbaum, Rebecca Klein, Paa Gyasi Hagan, Mark-Young Seadey, Naa Larteley Quarcoo, Rachel Hoffmann, Maria Robinson, Margaret Lartey, Marie C Leger
INTRODUCTION: Ghana is currently developing its provision of dermatology services. Epidemiologic studies of the skin diseases seen by Ghanaian dermatologists are needed to guide these efforts. We aimed to describe the skin conditions seen by and management practices of Ghanaian dermatologists in a specialized clinic. METHODS: We conducted a chart review of new patients presenting to the Korle Bu Teaching Hospital dermatology clinic during 2014. RESULTS: Among the 529 patients studied, 700 discrete diagnoses were made...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28528603/a-retrospective-study-of-multiple-sequential-light-and-laser-sources-to-activate-aminolevulinic-acid-in-the-treatment-of-acne-vulgaris
#8
Daniel P Friedmann, Mitchel P Goldman, Sabrina G Fabi, Isabella Guiha
Reports of the sequential use of multiple light and laser sources for topical 5-aminolevulinic acid (ALA) activation in photodynamic therapy (PDT) of inflammatory acne vulgaris are lacking. The authors sought to retrospectively compare field-directed ALA-PDT with blue light only, blue light + pulsed dye laser (PDL), blue light + intense pulsed light (IPL), blue light + PDL + IPL, or blue light + red light + PDL + IPL for inflammatory acne of the face or upper trunk. Results showed a trend toward greater patient-reported improvement with comparable tolerability using multiple, sequential light sources in ALA-PDT for acne vulgaris, albeit not statistically significant...
2017: Skinmed
https://www.readbyqxmd.com/read/28526023/high-incidence-of-periprosthetic-joint-infection-with-propionibacterium-acnes-after-the-use-of-a-stemless-shoulder-prosthesis-with-metaphyseal-screw-fixation-a-retrospective-cohort-study-of-241-patients-propionibacter-infections-after-eclipse-tsa
#9
Lisa Johansson, Nils P Hailer, Hans Rahme
BACKGROUND: A stemless shoulder prosthesis with humeral metaphyseal screw fixation was introduced in order to save bone-stock and to facilitate reconstruction of biomechanics (Eclipse®). The aim of this study was to analyze whether the risk of infection is different with this implant compared to conventional shoulder prosthesis. METHODS: Two hundred and forty-one patients (54.8% females) were operated with a shoulder arthroplasty and followed for median 2.0 (0...
May 19, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28525823/development-and-validation-of-a-reversed-phase-hplc-method-for-analysis-of-radiochemical-purity-in-123-i-ibzm
#10
Shiou-Shiow Farn, Yuen-Han Yeh, Chang-Chin Li, Ching-Shiuann Yang, Jenn-Tzong Chen, Chung-Shan Yu, Wuu-Jyh Lin
[(123)I]IBZM is used widely for in vivo imaging of D2 receptors in human brain and shows relatively fast kinetics and a greater susceptibility to synaptic dopamine release than other single-photon emission computed tomography (SPECT) radioligands. A reliable and reversed-phase HPLC method using UV/VIS and radiometric detectors has been developed for qualitative analysis of BZM and IBZM and radiochemical purity in [(123)I]IBZM preparations. The method uses gradient elution on a Zorbax XDB C-18 column with a mobile phase that consists of 10mM 3,3-dimethylglutaric acid (DMGA), pH 7...
April 15, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28524046/acne-conglobata-induced-by-adalimumab
#11
Galina Balakirski, Mark M Neis, Mosaad Megahed
No abstract text is available yet for this article.
May 19, 2017: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/28522046/generic-twice-daily-minocycline-versus-branded-extended-release-minocycline-for-acne-a-retrospective-comparison-of-treatment-escalation
#12
Preeta Gupta, Timothy Shin, Jennifer Sopkovich, Susan Massick, Benjamin H Kaffenberger
No abstract text is available yet for this article.
June 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28516256/-skin-diseases-associated-with-environmental-factors
#13
REVIEW
Vera Mahler
BACKGROUND: Multiple environmental exposures may derange the regulatory and repair mechanisms of the skin and lead to dermatological disease. OBJECTIVES: Provide an overview of non-allergic skin diseases associated with environmental factors. MATERIALS AND METHODS: Review of current scientific evidence for associations of non-allergic skin diseases with environmental exposures: irritation, chemicals, infection, UV-radiation, temperature. RESULTS: Predisposition (constitution e...
May 17, 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/28513546/edible-plants-and-their-influence-on-the-gut-microbiome-and-acne
#14
REVIEW
Ashley K Clark, Kelly N Haas, Raja K Sivamani
Acne vulgaris affects most people at some point in their lives. Due to unclear etiology, likely with multiple factors, targeted and low-risk treatments have yet to be developed. In this review, we explore the multiple causes of acne and how plant-based foods and supplements can control these. The proposed causative factors include insulin resistance, sex hormone imbalances, inflammation and microbial dysbiosis. There is an emerging body of work on the human gut microbiome and how it mediates feedback between the foods we eat and our bodies...
May 17, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28512669/combined-fractional-treatment-of-acne-scars-involving-non-ablative-1-550-nm-erbium-glass-laser-and-micro-needling-radiofrequency-a-16-week-prospective-randomized-split-face-study
#15
Hyuck Hoon Kwon, Hae Young Park, Sun Chul Choi, Youin Bae, Chanhee Kang, Jae Yoon Jung, Gyeong-Hun Park
An optimized therapeutic regimen involving a non-ablative fractionated laser or radiofrequency therapy for acne scars has not yet been established. To evaluate whether the combination of a non-ablative fractional laser (NAF) and fractional micro-needling radiofrequency (FMR) has clinical advantages for the treatment of atrophic acne scars compared with NAF alone, a 16-week prospective, randomized split-face study was performed. Each facial side of a patient was treated with 3 sessions of either NAF with FMR or NAF alone, with a 4-week interval between each session...
May 17, 2017: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/28511829/suicidal-behaviors-in-the-dermatology-patient
#16
Madhulika A Gupta, Daiana R Pur, Branka Vujcic, Aditya K Gupta
An assessment of suicidal behaviors in the dermatology patient may be necessary in several situations: (1) in the presence of psychiatric comorbidity (major depressive disorder, body dysmorphic disorder, substance use disorder, posttraumatic stress disorder), encountered in up to 30% of dermatology patients; (2) when dermatologic symptoms ("dysmorphophobia," dermatitis artefacta) represent psychiatric pathologic conditions; (3) when psychosocial stressors (bereavement, interpersonal violence) increase the risk of suicidal behavior and exacerbate stress-reactive dermatoses (psoriasis, acne); (4) in the presence of high disease burden (chronicity, increased disease severity); (5) in instances of significant pruritus or chronic sleep disruption; (6) in the presence of facial lesions or facial scarring; (7) when social exclusion or feelings of alienation arise secondary to the skin disorder; (8) with use of medications (retinoids, biologics) for which suicidal behavior has been implicated as a possible side effect; and (9) when treating psychiatric patients experiencing a serious reaction to psychotropic medications (eg, Stevens-Johnson syndrome and anticonvulsants)...
May 2017: Clinics in Dermatology
https://www.readbyqxmd.com/read/28511823/dissociation-and-conversion-symptoms-in-dermatology
#17
Madhulika A Gupta, Branka Vujcic, Aditya K Gupta
Dissociation and conversion (defined as the somatic component of dissociation) can play an important mediating role in the exacerbation of the stress-reactive dermatoses (eg, psoriasis, idiopathic urticaria, atopic dermatitis), dermatoses that are exacerbated by excessive scratching (eg, lichen simplex chronicus, prurigo nodularis) and koebnerization, and the self-induced dermatoses (dermatitis artefacta, acne excoriée, skin picking disorder, trichotillomania, onychotillomania/onychophagia). Dissociative symptoms often coexist with obsessive-compulsive symptoms in the more severe cases of the self-induced dermatoses...
May 2017: Clinics in Dermatology
https://www.readbyqxmd.com/read/28511158/evolution-of-some-indicators-of-systemic-immunity-in-patients-with-acne-while-using-laser-therapy
#18
Marianna Dashko, Orysya Syzon, Iryna Voznyak
INTRODUCTION: One of the important problems in modern dermatology is to improve treatment efficiency of acne being a common cause for cicatricial skin changes, loss of performance capability and social activity and negatively affects the psycho-emotional state of patients and their quality of life. The topicality of the disease is due to the high degree of its proliferation, chronic and recurrent course, and resistance to existing therapies. Reducing the effectiveness of skin diseases treatment, including that of acne, at present, is associated with developing resistance to drugs, which causes the use of non-drug methods in dermatology nowadays, including low-intensity laser therapy...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28507783/periprosthetic-shoulder-infection-an-overview
#19
REVIEW
Nicolas Bonnevialle, Florence Dauzères, Julien Toulemonde, Fanny Elia, Jean-Michel Laffosse, Pierre Mansat
Periprosthetic shoulder infection (PSI) is rare but potentially devastating. The rate of PSI is increased in cases of revision procedures, reverse shoulder implants and co-morbidities. One specific type of PSI is the occurrence of low-grade infections caused by non-suppurative bacteria such as Propionibacterium acnes or Staphylococcus epidemermidis.Success of treatment depends on micro-organism identification, appropriate surgical procedures and antibiotic administration efficiency. Post-operative early PSI can be treated with simple debridement, while chronic PSI requires a one- or two-stage revision procedure...
April 2017: EFORT Open Rev
https://www.readbyqxmd.com/read/28504479/contribution-of-anthocyanin-rich-foods-in-obesity-control-through-gut-microbiota-interactions
#20
REVIEW
Giovana Jamar, Débora Estadella, Luciana Pellegrini Pisani
Obesity is characterized by low-grade inflammation and a number of metabolic disorders. Distal gut microbes' content (microbiota) is not yet fully understood but evidence shows that it is influenced by internal and external factors that modulate its composition and function. The evidence that gut microbiota composition can differ between healthy and obese individuals, as well as for those who maintain specific dietary habits, has led to the study of this environmental factor as a key link between the pathophysiology of obesity and gut microbiota...
May 15, 2017: BioFactors
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